["My work is sending me on a business trip, but I'm really nervous about getting on the plane.", 'A little anxious?  Have you ever flown on a plane before?', 'I have. I fly a lot, actually. I just really really hate it. I get so worried and afraid. Hopefully the time will pass quickly.']
I'm sure you'll be fine. Statistically its safer than driving.
I'm going on a work trip this weekend, but I hate flying. I'm really nervous about the flight.