Triptodur Uses, Side Effects & Warnings - Drugs.com

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# Triptodur

Generic name: triptorelin [ TRIP-toe-REL-in ]
Brand names: Trelstar, Triptodur
Drug class: Gonadotropin releasing hormones

Medically reviewed by Drugs.com on Jun 22, 2022. Written by Cerner Multum.

## What is Triptodur?

Triptodur is a man-made form of a hormone that regulates many processes in the body.

The Trelstar brand of triptorelin is used in men to treat the symptoms of prostate cancer. Trelstar treats only the symptoms of prostate cancer and does not treat the cancer itself.

The Triptodur brand of triptorelin is used to treat precocious puberty in boys and girls who are at least 2 years old.

Triptodur may also be used for purposes not listed in this medication guide.

## Warnings

Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment.

Some people using Triptodur have had new or worsening mental problems or seizures (convulsions). Call your doctor right away if you have a seizure, or any unusual changes in mood or behavior (anger, aggression, crying, feeling restless or irritable).

Triptodur can cause a temporary increase in certain hormones, especially when you first start using Triptodur. This may cause side effects that are similar to the condition being treated.

## Before taking this medicine

You should not use this medication if you are allergic to Triptodur or similar drugs such as leuprolide (Lupron, Viadur, Eligard) or goserelin (Zoladex).

Do not use Triptodur if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine.

Tell your doctor if you have ever had:

- heart disease, long QT syndrome or other heart rhythm disorder;

- a heart attack or stroke;

- an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);

- diabetes;

- epilepsy or other seizure disorder;

- mental illness; or

- a tumor or blood vessel problem in your brain.

Ask a doctor if it is safe to breastfeed while using this medicine.

This medicine may affect fertility (ability to have children) in men.

## Related/similar drugs

tamoxifen, Lupron, leuprolide, triptorelin, Nolvadex, Soltamox

## How should I use Triptodur?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Triptodur is injected into a muscle. A healthcare provider can teach you how to properly use the medication by yourself.

Triptodur is usually given once every 4, 12, or 24 weeks. Your dose schedule will depend on the strength and brand of triptorelin you are using.

Triptodur must be mixed with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.

Triptodur can increase certain hormones when you first start using Triptodur or after each new injection. This may cause symptoms of prostate cancer or precocious puberty to get worse for a short time. These side effects should get better within 1 to 2 months. Call your doctor if your symptoms do not improve, or if they get worse while using this medicine.

You may need frequent medical tests.

Store at room temperature away from moisture and heat. Do not freeze.

Each vial (bottle) is for one use only. Throw it away after one use, even if there is still medicine left inside.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

Detailed Triptodur dosage information

## What happens if I miss a dose?

Call your doctor for instructions if you miss a dose, or if you miss an appointment for your Triptodur.

## What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

## What should I avoid while using Triptodur?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

## Triptodur side effects

Get emergency medical help if you have signs of an allergic reaction: hives, red skin rash, severe itching, sweating; dizziness, fast heartbeats; trouble breathing or swallowing; swelling of your face, lips, tongue, or throat.

Some people using Triptodur have had new or worsening mental problems or seizures (convulsions). Call your doctor right away if you have a seizure, or any unusual changes in mood or behavior (anger, aggression, crying, feeling restless or irritable).

Triptodur can cause a temporary increase in certain hormones, especially when you first start using Triptodur. This may cause side effects that are similar to the condition being treated. Call your doctor at once if you have:

- painful or difficult urination, burning when you urinate, blood in the urine;

- bone pain;

- (in children) new or worsening signs of puberty;

- a seizure;

- chest pain or pressure, pain spreading to your jaw or shoulder;

- sudden numbness or weakness, slurred speech;

- loss of movement in any part of your body;

- increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;

- high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor; or

- nerve problems--back pain, muscle weakness, problems with balance or coordination, severe numbness or tingling in your legs or feet, loss of bladder or bowel control.

Common side effects of Triptodur may include:

- pain, swelling, itching, or redness where an injection was given;

- hot flashes;

- decreased interest in sex, impotence, trouble having an orgasm;

- headache, bone pain, pain or swelling in your legs;

- nausea, vomiting, diarrhea, upset stomach;

- vaginal bleeding; or

- cold or flu symptoms (stuffy nose, sneezing, cough, sore throat, ear pain).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Triptodur side effects (more detail)

## What other drugs will affect Triptodur?

Other drugs may affect Triptodur, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Triptodur drug interactions (more detail)

## Where can I get more information?

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

## Popular FAQ

How long can I take Trelstar (triptorelin) for prostate cancer?

Trelstar (triptorelin) can be given for prostate cancer as long as it is tolerated and your doctor believes it is still safe and effective for you, which may be many years. Trelstar is intended as a long-term treatment, and despite the inevitable progression to castration-resistant prostate cancer (CRPC) in most patients receiving androgen deprivation therapies (ADT), such as Trelstar, there may still be benefits in continuing ADT in men in addition to introducing other treatment options for CRPC. Continue reading

Why is triptorelin used for prostate cancer?

Triptorelin may be used in advanced prostate cancer to lower levels of testosterone in men. Prostate cancer needs the hormone testosterone to grow. Almost all testosterone in men is made by the testicles. Triptorelin stops the testicles from making testosterone, reducing testosterone levels, and slowing or stopping the growth of cancer cells. This can help relieve symptoms such as painful or difficult urination. Continue reading

### More FAQ

- What is Triptodur used to treat?

## More about Triptodur (triptorelin)

- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: gonadotropin releasing hormones
- En español

### Patient resources

- Advanced Reading

#### Other brands

Trelstar

### Professional resources

- Prescribing Information

### Related treatment guides

- Precocious Puberty

## Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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