Sodium phosphate dibasic and sodium phosphate monobasic Intravenous Advanced Patient Information - Drugs.com

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# Sodium phosphate dibasic and sodium phosphate monobasic (Intravenous)

Medically reviewed by Drugs.com. Last updated on Sep 17, 2022.

Available Dosage Forms:

- Solution

Therapeutic Class: Parenteral Electrolyte, Sodium

## Uses for sodium phosphate dibasic and sodium phosphate monobasic

Sodium phosphate dibasic and sodium phosphate monobasic combination injection is a phosphate replacement that is used to treat or prevent hypophosphatemia (low phosphorus in the blood). It is also used as an additive in the preparation of fluid formula injections. Sodium phosphate dibasic and sodium phosphate monobasic is given to patients who cannot receive a phosphate supplement by mouth.

Sodium phosphate dibasic and sodium phosphate monobasic is to be given only by or under the direct supervision of a doctor.

## Before using sodium phosphate dibasic and sodium phosphate monobasic

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For sodium phosphate dibasic and sodium phosphate monobasic, the following should be considered:

### Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to sodium phosphate dibasic and sodium phosphate monobasic or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

### Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of sodium phosphates injection in children. Safety and efficacy have been established.

### Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sodium phosphates injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving sodium phosphate dibasic and sodium phosphate monobasic.

### Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

### Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving sodium phosphate dibasic and sodium phosphate monobasic, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using sodium phosphate dibasic and sodium phosphate monobasic with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

- Bepridil
- Cisapride
- Dronedarone
- Levoketoconazole
- Mesoridazine
- Pimozide
- Piperaquine
- Saquinavir
- Sparfloxacin
- Terfenadine
- Thioridazine
- Ziprasidone

Using sodium phosphate dibasic and sodium phosphate monobasic with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

- Alfuzosin
- Amiodarone
- Amisulpride
- Amitriptyline
- Amoxapine
- Anagrelide
- Apomorphine
- Aripiprazole
- Aripiprazole Lauroxil
- Arsenic Trioxide
- Asenapine
- Astemizole
- Azithromycin
- Bedaquiline
- Buprenorphine
- Buserelin
- Ceritinib
- Chloroquine
- Chlorpromazine
- Ciprofloxacin
- Citalopram
- Clarithromycin
- Clofazimine
- Clomipramine
- Clothiapine
- Clozapine
- Crizotinib
- Dabrafenib
- Dasatinib
- Degarelix
- Delamanid
- Desipramine
- Deslorelin
- Deutetrabenazine
- Dexmedetomidine
- Disopyramide
- Dofetilide
- Dolasetron
- Domperidone
- Donepezil
- Droperidol
- Efavirenz
- Encorafenib
- Entrectinib
- Erdafitinib
- Erythromycin
- Escitalopram
- Fexinidazole
- Fingolimod
- Flecainide
- Fluconazole
- Fluoxetine
- Formoterol
- Foscarnet
- Fostemsavir
- Gatifloxacin
- Gemifloxacin
- Glasdegib
- Gonadorelin
- Goserelin
- Granisetron
- Halofantrine
- Haloperidol
- Histrelin
- Hydroxychloroquine
- Hydroxyzine
- Ibutilide
- Iloperidone
- Imipramine
- Inotuzumab Ozogamicin
- Ivabradine
- Ivosidenib
- Ketoconazole
- Lapatinib
- Lefamulin
- Lenvatinib
- Leuprolide
- Levofloxacin
- Lofexidine
- Lopinavir
- Lumefantrine
- Macimorelin
- Mefloquine
- Methadone
- Metronidazole
- Mifepristone
- Mirtazapine
- Mobocertinib
- Moxifloxacin
- Nafarelin
- Nilotinib
- Norfloxacin
- Nortriptyline
- Octreotide
- Ofloxacin
- Ondansetron
- Osilodrostat
- Osimertinib
- Oxaliplatin
- Ozanimod
- Pacritinib
- Paliperidone
- Panobinostat
- Pasireotide
- Pazopanib
- Pimavanserin
- Pitolisant
- Ponesimod
- Posaconazole
- Procainamide
- Prochlorperazine
- Promethazine
- Propafenone
- Protriptyline
- Quetiapine
- Quinidine
- Quinine
- Ranolazine
- Ribociclib
- Selpercatinib
- Sertraline
- Sevoflurane
- Siponimod
- Solifenacin
- Sorafenib
- Sotalol
- Sulpiride
- Sunitinib
- Tacrolimus
- Telavancin
- Telithromycin
- Tetrabenazine
- Trazodone
- Triclabendazole
- Trimipramine
- Triptorelin
- Vandetanib
- Vardenafil
- Vemurafenib
- Vilanterol
- Vinflunine
- Voclosporin
- Voriconazole
- Zuclopenthixol

### Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

### Other medical problems

The presence of other medical problems may affect the use of sodium phosphate dibasic and sodium phosphate monobasic. Make sure you tell your doctor if you have any other medical problems, especially:

- Heart failure or
- Kidney disease or
- Liver disease—Use with caution. May make these conditions worse.

- Hypernatremia (high sodium in the blood) or
- Hyperphosphatemia (high phosphorus in the blood) or
- Hypocalcemia (low calcium in the blood)—Should not be used in patients with these conditions.

## Related/similar drugs

MiraLAX, erythromycin, Colace, docusate, bisacodyl, senna, magnesium oxide

## Proper use of sodium phosphate dibasic and sodium phosphate monobasic

A nurse or other trained health professional will give you sodium phosphate dibasic and sodium phosphate monobasic in a medical facility. Sodium phosphate dibasic and sodium phosphate monobasic is given through a needle placed in a vein.

Detailed Sodium biphosphate / sodium phosphate dosage information

## Precautions while using sodium phosphate dibasic and sodium phosphate monobasic

Your doctor will check your progress closely while you are receiving sodium phosphate dibasic and sodium phosphate monobasic to see if the medicine is working properly and to decide if you should continue to receive it. Blood and urine tests may be needed to check for unwanted effects.

Sodium phosphate dibasic and sodium phosphate monobasic contains aluminum which can cause harm especially to premature babies. Talk to your doctor if you have concerns about this.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

## Sodium phosphate dibasic and sodium phosphate monobasic side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

- Confusion
- irregular heartbeats
- mood or mental changes
- muscle cramps in the hands, arms, feet, legs, or face
- numbness and tingling around the mouth, fingertips, or feet
- seizures
- stomach cramps
- tremor
- trouble breathing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Sodium biphosphate / sodium phosphate side effects (more detail)

## More about sodium biphosphate / sodium phosphate

- Check interactions
- Pricing & coupons
- Reviews (115)
- Side effects
- Dosage information
- During pregnancy
- Drug class: laxatives

### Patient resources

- Drug Information
- Sodium biphosphate and sodium phosphate rectal
- Sodium phosphate dibasic and sodium phosphate monobasic (Advanced Reading)
- Sodium phosphate dibasic and sodium phosphate monobasic Rectal (Advanced Reading)
- Sodium Phosphates Tablets

#### Other brands

Fleet Enema, OsmoPrep, Fleet Phospho Soda, Disposable Enema, Visicol

### Professional resources

- Prescribing Information

### Related treatment guides

- Bowel Preparation
- Constipation

## Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer