Clocortolone Topical application Advanced Patient Information - Drugs.com

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# Clocortolone (Topical application)

Medically reviewed by Drugs.com. Last updated on Dec 4, 2022.

## Commonly used brand name(s)

In the U.S.

- Cloderm

Available Dosage Forms:

- Cream

Therapeutic Class: Corticosteroid, Weak

Pharmacologic Class: Clocortolone

## Uses for clocortolone

Clocortolone topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions (corticosteroid-responsive dermatoses). Clocortolone is a corticosteroid (cortisone-like medicine or steroid).

Clocortolone is available only with your doctor's prescription.

## Before using clocortolone

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For clocortolone, the following should be considered:

### Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to clocortolone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

### Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of clocortolone topical in children. However, because of clocortolone's toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using clocortolone, follow your doctor's instructions very carefully.

### Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of clocortolone topical in the elderly.

### Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

### Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

### Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

### Other medical problems

The presence of other medical problems may affect the use of clocortolone. Make sure you tell your doctor if you have any other medical problems, especially:

- Cushing's syndrome (adrenal gland problem) or
- Diabetes or
- Glucosuria (sugar in the urine) or
- Hyperglycemia (high blood sugar) or
- Intracranial hypertension (increased pressure in the head)—Use with caution. May make these conditions worse.

- Infection of the skin at or near the place of application—The chance of side effects may be increased.

## Related/similar drugs

Taltz, prednisone, methotrexate, Humira, cyclosporine, Dupixent, Remicade

## Proper use of clocortolone

It is very important that you use clocortolone only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

Clocortolone is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Rinse it off right away if it does get on these areas.

To use:

- Wash your hands with soap and water before and after using clocortolone.
- Apply a thin layer of clocortolone to the affected area of the skin. Rub it in gently.
- Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.
- If the medicine is applied to the diaper area of an infant, do not use tight-fitting diapers or plastic pants.
- If your doctor ordered an occlusive dressing (eg, bandage) or airtight covering to be applied over the medicine, make sure you know how to apply it. Occlusive dressings increase the amount of medicine absorbed through your skin, so use them only as directed. If you have any questions about this, check with your doctor.

Clocortolone should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. Clocortolone should not be used to treat certain kinds of skin infections or conditions.

### Dosing

The dose of clocortolone will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of clocortolone. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

- For corticosteroid-responsive dermatoses:
  - For topical dosage forms (cream):
    - Adults—Apply to the affected area of the skin 3 times a day.
    - Children—Use and dose must be determined by your doctor.

### Missed dose

If you miss a dose of clocortolone, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

### Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Clocortolone topical dosage information

## Precautions while using clocortolone

It is very important that your doctor check the progress of you or your child at regular visits to make sure that clocortolone is working properly. Blood and urine tests are needed to check for unwanted effects.

If your or your child's symptoms do not improve, or if they become worse, check with your doctor.

Using too much of clocortolone or using it for a long time may increase your risk of having adrenal or pituitary gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have blurred vision, darkening of the skin, diarrhea, dizziness or fainting, a fast, irregular, or pounding heartbeat, increased thirst or urination, irritability, loss of appetite, mental depression, nausea, skin rash, or unusual tiredness or weakness, or vomiting.

Clocortolone may cause serious skin reactions, which may occur if you cover the treated skin area or use the medicine for a long time. Check with your doctor right away if you or your child have thinning of the skin with easy bruising, reddish purple lines on the arms, face, legs, trunk, or groin areas, acne or pimples, darkening or lightening of skin color, blistering, burning, crusting, dryness, flaking of the skin, or itching, scaling, severe redness, soreness, swelling of the skin.

Check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin. Do not use cosmetics or other skin care products on the treated areas.

Clocortolone may delay growth in children. If you think your child is not growing properly while using clocortolone, talk with your doctor.

## Clocortolone side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

- Backache
- blistering, burning, crusting, dryness, or flaking of the skin
- blurred or changes in vision
- bulging soft spot on head of an infant
- burning, itching, and pain in the hairy areas, pus at the root of the hair
- burning and itching of the skin with pinhead-sized red blisters
- confusion
- facial hair growth in females
- fractures
- full or round face, neck, or trunk
- headache
- increased hair growth on the forehead, back, arms, and legs
- increased hunger or thirst
- increased pressure in the head
- increased urination
- irritability
- lightening of the normal skin color
- lightening of treated areas of the dark skin
- loss of sexual desire or ability
- menstrual irregularities
- muscle wasting
- severe nausea or vomiting
- severe redness, soreness, or swelling of the skin
- softening of the skin
- thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
- unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

- Acne, pimples

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Clocortolone topical side effects (more detail)

## More about clocortolone topical

- Check interactions
- Pricing & coupons
- Reviews (9)
- Side effects
- Dosage information
- During pregnancy
- Drug class: topical steroids
- Breastfeeding
- En español

### Patient resources

- Drug Information

#### Other brands

Cloderm

### Professional resources

- Prescribing Information

### Related treatment guides

- Atopic Dermatitis
- Dermatitis
- Eczema
- Psoriasis

## Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer