Artiss Duo Set Uses, Side Effects & Warnings - Drugs.com

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# Artiss Duo Set

Generic name: fibrin sealant topical [ FYE-brin-SEE-lant-TOP-i-kal ]
Brand names: Artiss, Artiss Duo Set, Artiss Duploject, Tisseel, Tisseel Duploject Kit, Tisseel Valupak Kit
Drug class: Miscellaneous coagulation modifiers

Medically reviewed by Drugs.com on Jan 24, 2022. Written by Cerner Multum.

## What is Artiss Duo Set?

Fibrin sealant is made of two substances from human plasma that work together to help your blood clot.

Artiss Duo Set is used to help control bleeding during surgery when other ways to close a wound or incision (such as stitches, bands, or heat) cannot be used. This medicine may also be used to prevent leaks from a wound left in stomach tissue after a colostomy is removed.

Artiss Duo Set is sometimes used to help skin tissues stick together during skin graft procedures or cosmetic surgery.

Artiss Duo Set may also be used for purposes not listed in this medication guide.

## Warnings

You should not be treated with Artiss Duo Set if you are allergic to cows or products made from cows.

## Before taking this medicine

You should not be treated with Artiss Duo Set if you are allergic to cows or products made from cows.

It is not known whether Artiss Duo Set will harm an unborn baby. Tell your doctor if you are pregnant.

It is not known whether fibrin sealant topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

## How should I use Artiss Duo Set?

Artiss Duo Set can be sprayed or dripped onto the affected skin or surgical area. Artiss Duo Set is applied by a healthcare professional in a surgical or clinical setting.

Artiss Duo Set is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

Some people develop symptoms of a viral infection after being treated with Artiss Duo Set. Call your doctor if you have flu-like symptoms such as fever, chills, drowsiness, or a runny nose. You may also have joint pain and a skin rash about 2 weeks after the start of your flu symptoms.

Detailed Artiss dosage information

## Related/similar drugs

thrombin topical, Tisseel, VistaSeal, fibrin sealant topical

## What happens if I miss a dose?

Because you will receive Artiss Duo Set in a clinical setting, you are not likely to miss a dose.

## What happens if I overdose?

Since Artiss Duo Set is applied by a healthcare professional in a medical setting, an overdose is unlikely to occur.

## What should I avoid after being treated with Artiss Duo Set?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

## Artiss Duo Set side effects

Get emergency medical help if you have signs of an allergic reaction: hives, itching, warmth, redness, numbness, tingly feeling; nausea, vomiting, feeling light-headed, fast or slow heartbeats; wheezing, chest tightness, trouble breathing; swelling of your face, lips, tongue, or throat.

Fibrin sealant is sometimes applied with a spray device that uses gas pressure. High pressure may cause the release of air or gas under the skin tissues, where it can then travel throughout the body. This may be more likely when high pressure settings are improperly used by a healthcare provider during the spray application of fibrin sealant. Air or gas trapped within the body can cause serious or life-threatening effects. Talk with your doctor about this risk.

Tell your caregivers at once if you have:

- chest pain, cough, trouble breathing, gasping for breath;

- confusion, agitation, panic, extreme fear;

- sudden numbness or weakness (especially on one side of the body);

- sudden severe headache, slurred speech, problems with vision or balance;

- blue-colored appearance of your skin or lips;

- nausea, dizziness or spinning sensation;

- a light-headed feeling, like you might pass out; or

- redness, itching, irritation, or slow healing of the skin wound or treated area;

Common side effects of Artiss Duo Set may include:

- itching; or

- swelling or bruising.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Artiss side effects (more detail)

## What other drugs will affect Artiss Duo Set?

It is not likely that other drugs you take orally or inject will have an effect on topically applied fibrin sealant. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

## Where can I get more information?

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

## More about Artiss (fibrin sealant topical)

- Pricing & coupons
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: miscellaneous coagulation modifiers

### Patient resources

- Drug Information
- Artiss Duploject

#### Other brands

Tisseel

### Related treatment guides

- Closure of Colostomy
- Hemostasis

## Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 3.03.