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# Cobal (Intramuscular)

Generic name: cyanocobalamin (intramuscular route) [ sye-an-oh-koe-BAL-a-min ]
Drug class: Vitamins

Medically reviewed by Drugs.com. Last updated on Sep 26, 2022.

The Cobal 1000 brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

## Commonly used brand name(s)

In the U.S.

- Cobal
- LA-12
- Neuroforte-R
- Vita #12
- Vitabee 12

In Canada

- Bedoz

Available Dosage Forms:

- Solution

Therapeutic Class: Nutritive Agent

Pharmacologic Class: Vitamin B (class)

## Uses for Cobal

Cyanocobalamin injection is used to treat or prevent vitamin B12 deficiency caused by the following conditions:

- Addisonian (pernicious) anemia
- Stomach or bowel problems
- Worm infestation
- Pancreas or bowel cancer
- Folic acid deficiency.

This medicine is to be given only by or under the direct supervision of your doctor.

## Before using Cobal

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

### Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

### Pediatric

Normal daily requirements of vitamin B12 vary according to age.

### Geriatric

No information is available on the relationship of age to the effects of cyanocobalamin injection in geriatric patients.

### Breastfeeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

### Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

- Chloramphenicol

### Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

### Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

- Allergy to cobalt—Should not be used in patients with this condition.

- Kidney disease—Use with caution. May increase risk for more serious side effects.

- Megaloblastic anemia, severe—May increase risk for hypokalemia.

## Proper use of Cobal

This section provides information on the proper use of a number of products that contain cyanocobalamin. It may not be specific to Cobal. Please read with care.

A nurse or other trained health professional will give you this medicine. This medicine is given as a shot into a muscle.

If you are using this medicine to treat vitamin B12 deficiency caused by pernicious anemia, you will need to use the medicine for the rest of your life.

Tell your doctor if you are on a vegetarian diet.

Detailed Cobal 1000 dosage information

## Precautions while using Cobal

It is very important that your doctor check the progress of you or your child at regular visits. This will allow your doctor to see if the medicine is working properly. Blood and other laboratory tests may be needed to check for unwanted effects.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

## Cobal side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

- Abdominal or stomach pain
- bleeding from the gums or nose
- blue lips and fingernails
- chest pain
- cough
- coughing that sometimes produces a pink frothy sputum
- decreased urine output
- difficult, fast, noisy breathing, sometimes with wheezing
- difficulty with swallowing
- dilated neck veins
- dizziness
- extreme fatigue
- eye pain
- fast heartbeat
- headache
- hives, itching, or skin rash
- increased sweating
- irregular breathing
- irregular heartbeat
- pale skin
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- ringing in the ears
- swelling of the face, fingers, feet, or lower legs
- tightness in the chest
- unusual tiredness or weakness
- weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

- Diarrhea
- skin rash with a general disease

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Cobal 1000 side effects (more detail)

## More about Cobal 1000 (cyanocobalamin)

- Check interactions
- Side effects
- Dosage information
- During pregnancy
- Drug class: vitamins

### Patient resources

- Patient Information

#### Other brands

Vitamin B12, Nascobal, CaloMist, Neuroforte-R, ... +4 more

### Professional resources

- Prescribing Information

### Related treatment guides

- B12 Nutritional Deficiency
- Pernicious Anemia
- Schilling Test
- Vitamin B12 Deficiency

## Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer