Mutamycin Uses, Side Effects & Warnings - Drugs.com

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# Mutamycin

Generic name: mitomycin [ MYE-toe-MYE-sin ]
Drug class: Antibiotics / antineoplastics

Medically reviewed by Drugs.com on Feb 3, 2021. Written by Cerner Multum.

## What is Mutamycin?

Mutamycin is used in combination with other cancer drugs to treat cancer of the stomach and pancreas.

Mutamycin may also be used for purposes not listed in this medication guide.

## Warnings

Mutamycin can damage red blood cells, which may cause irreversible kidney failure. Tell your doctor right away if you have unusual bruising or bleeding, pale skin, confusion, tiredness or irritability, stomach pain, bloody diarrhea, red or pink urine, swelling, rapid weight gain, and little or no urinating.

Mutamycin can also weaken (suppress) your immune system, and you may get an infection more easily. Call your doctor if you have signs of infection (fever, weakness, cold or flu symptoms, skin sores, frequent or recurring illness).

## Before taking this medicine

You should not be treated with Mutamycin if you are allergic to it, or if you have:

- low levels of platelets in your blood;

- bone marrow suppression; or

- active bleeding or any risk of bleeding.

Tell your doctor if you have ever had:

- kidney disease;

- heart disease; or

- asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder.

Mutamycin may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

You should not breastfeed while using Mutamycin.

## How is Mutamycin given?

Mutamycin is given as an infusion into a vein. A healthcare provider will give you Mutamycin.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Mutamycin is injected.

Some people receiving Mutamycin have developed ulcers on the skin where an injection was given, or on other areas of body. Skin changes may occur several weeks or months after a this medicine injection. Call your doctor if you notice any redness, sores, oozing, or other skin changes during or after your treatment with this medicine.

Mutamycin affects your immune system. You may get infections more easily. You will need frequent medical tests, and your next dose may be delayed based on the results.

Mutamycin can have long lasting effects on your body. You may also need medical tests for a short time after your last dose.

Detailed Mutamycin dosage information

## Related/similar drugs

cisplatin, fluorouracil, doxorubicin, nivolumab, Opdivo, gemcitabine, everolimus

## What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Mutamycin.

## What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

## What should I avoid while receiving Mutamycin?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

## Mutamycin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Mutamycin can damage red blood cells, which may cause irreversible kidney failure. Tell your doctor right away if you have unusual bruising or bleeding, pale skin, confusion, tiredness or irritability, stomach pain, bloody diarrhea, red or pink urine, swelling, rapid weight gain, and little or no urinating.

Mutamycin may cause serious side effects. Call your doctor at once if you have:

- signs of infection (fever, weakness, cold or flu symptoms, skin sores, frequent or recurring illness);

- wheezing, chest tightness, new or worsening cough, trouble breathing;

- blisters or ulcers in your mouth, red or swollen gums, trouble swallowing; or

- pain, burning, redness, swelling, irritation, or skin changes where the injection was given.

Common side effects of Mutamycin may include:

- fever or other signs of infection;

- nausea, vomiting, diarrhea, loss of appetite;

- mouth sores;

- drowsiness, headache;

- blurred vision; or

- temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Mutamycin side effects (more detail)

## What other drugs will affect Mutamycin?

Other drugs may affect Mutamycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Mutamycin drug interactions (more detail)

## Where can I get more information?

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

## More about Mutamycin (mitomycin)

- Check interactions
- Pricing & coupons
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: antibiotics/antineoplastics
- En español

### Patient resources

- Advanced Reading
- Mutamycin Injection (Advanced Reading)

#### Other brands

Jelmyto

### Professional resources

- Prescribing Information

### Related treatment guides

- Bladder Cancer
- Pancreatic Cancer
- Stomach Cancer

## Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 6.01.