Deucravacitinib Uses, Side Effects & Warnings - Drugs.com

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# Deucravacitinib

Generic name: deucravacitinib (due krav a sye ti nib)
Brand name: Sotyktu
Dosage form: oral tablet (6 mg)
Drug class: Multikinase inhibitors

Medically reviewed by Drugs.com on Nov 29, 2022. Written by Cerner Multum.

## What is deucravacitinib?

Deucravacitinib is used to treat adults with moderate to severe plaque psoriasis.

Deucravacitinib may also be used for purposes not listed in this medication guide.

## Warnings

Serious infections may occur during treatment with deucravacitinib. Call your doctor right away if you have signs of infection such as: fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very tired, skin warmth or redness, painful skin sores, or coughing up blood.

Deucravacitinib can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.

## Before taking this medicine

You should not use deucravacitinib if you are allergic to it.

Tell your doctor if you have ever had:

- liver or kidney disease;

- hepatitis B or C;

- high blood levels of fat (triglycerides);

- any type of cancer;

- tuberculosis or have been exposed to tuberculosis;

- if you have an infection that keeps returning or does not go away;

- if you are being treated for an infection;

- if you have recently received or are scheduled to receive a vaccine; or

- if you have high blood pressure, high cholesterol, diabetes, menopause (women), family history of coronary artery disease, being overweight, or being over 50, or if you smoke.

Tell your doctor if you are pregnant or breastfeeding.

## How should I take deucravacitinib?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take deucravacitinib once every day, with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

You will need medical tests before you start taking deucravacitinib and while taking deucravacitinib.

Store at room temperature away from moisture and heat.

## What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

## What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

## What should I avoid while taking deucravacitinib?

Avoid receiving a "live" vaccine. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

## Deucravacitinib side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Deucravacitinib can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.

Also call your doctor at once if you have:

- signs of infection--fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very tired, skin warmth or redness, painful skin sores, or coughing up blood.

Common side effects of deucravacitinib may include:

- cold symptoms such as stuffy nose, sneezing, sore throat;

- cold sores, sores on your gums, tongue or mouth;

- folliculitis (redness or crusting around your hair follicles); or

- acne.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Deucravacitinib side effects (more detail)

## Deucravacitinib dosing information

Usual Adult Dose for Plaque Psoriasis:

6 mg orally once daily, with or without food
Comments:
-Evaluate patients for latent and active tuberculosis (TB) infection and initiate anti-TB therapy before administering this drug.
Use: Treatment of moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy

Detailed Deucravacitinib dosage information

## What other drugs will affect deucravacitinib?

Other drugs may affect deucravacitinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Deucravacitinib drug interactions (more detail)

## Where can I get more information?

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

## More about deucravacitinib

- Check interactions
- Side effects
- Dosage information
- During pregnancy
- Drug class: multikinase inhibitors
- En español

### Patient resources

- Advanced Reading

#### Other brands

Sotyktu

### Professional resources

- Prescribing Information

### Related treatment guides

- Plaque Psoriasis

## Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 1.01.