Bio-Cef Advanced Patient Information - Drugs.com

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# Bio-Cef (Oral)

Generic name: cephalexin (oral route) [ sef-a-LEX-in ]
Drug class: First generation cephalosporins

Medically reviewed by Drugs.com. Last updated on Jan 3, 2023.

The Biocef brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

## Commonly used brand name(s)

In the U.S.

- Bio-Cef
- Keflex
- Panixine DisperDose

In Canada

- Novo-Lexin

Available Dosage Forms:

- Capsule
- Tablet
- Powder for Suspension

Therapeutic Class: Antibiotic

Pharmacologic Class: 1st Generation Cephalosporin

## Uses for Bio-Cef

Cephalexin is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

## Before using Bio-Cef

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

### Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

### Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of cephalexin in children.

### Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cephalexin in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cephalexin.

### Breastfeeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

### Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

- Dofetilide

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

- Cholera Vaccine, Live
- Probenecid
- Warfarin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

- Cholestyramine

### Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

### Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

- Colitis (inflammation in gut), history of or
- Diarrhea, severe, history of or
- Seizures, history of—Use with caution. May make these conditions worse.

- Kidney disease or
- Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

## Related/similar drugs

prednisone, amoxicillin, doxycycline, azithromycin, ciprofloxacin, metronidazole, cephalexin

## Proper use of Bio-Cef

This section provides information on the proper use of a number of products that contain cephalexin. It may not be specific to Bio-Cef. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Shake the oral liquid well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

### Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

- For oral dosage forms (capsules or suspension):
  - For infections:
    - Adults and children 15 years of age and older—1000 to 4000 milligrams (mg) per day, taken in divided doses.
    - Children 1 year of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 25 to 100 milligrams (mg) per kilogram (kg) per day, taken in divided doses.
    - Children younger than 1 year of age—Use and dose must be determined by your doctor.

### Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

### Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the oral liquid in the refrigerator. Throw away any unused medicine after 14 days.

Detailed Biocef dosage information

## Precautions while using Bio-Cef

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Serious allergic reactions can occur with this medicine. Check with your doctor right away if you have chest pain, blistering, peeling, or loose skin, red skin lesions, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, severe acne or skin rash, sores or ulcers on the skin, trouble breathing or swallowing, or fever or chills while you are using this medicine.

Cephalexin may cause diarrhea, and in some cases it can be severe. Do not take any medicine or give medicine to your child to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Before you or your child have any medical tests, tell the medical doctor in charge that you are using this medicine. The results of some tests may be affected by this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

## Bio-Cef side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

- Diarrhea

Rare

- Abdominal or stomach pain
- blistering, peeling, or loosening of the skin
- chills
- clay-colored stools
- cough
- dark urine
- diarrhea
- dizziness
- fever
- general tiredness and weakness
- headache
- itching or rash
- joint or muscle pain
- light-colored stools
- loss of appetite
- nausea and vomiting
- red skin lesions, often with a purple center
- red, irritated eyes
- sore throat
- sores, ulcers, or white spots in the mouth or on the lips
- unpleasant breath odor
- unusual tiredness or weakness
- upper right abdominal or stomach pain
- vomiting of blood
- yellow eyes or skin

Incidence not known

- Abdominal or stomach cramps or tenderness
- back or leg pains
- black, tarry stools
- bleeding gums
- bloating
- blood in the urine or stools
- chest pain
- coughing up blood
- diarrhea, watery and severe, which may also be bloody
- difficulty with breathing or swallowing
- fast heartbeat
- general body swelling
- hives
- increased menstrual flow or vaginal bleeding
- increased thirst
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- loss of appetite
- nosebleeds
- pain
- painful or difficult urination
- pale skin
- paralysis
- pinpoint red spots on the skin
- prolonged bleeding from cuts
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- red or black, tarry stools
- red or dark brown urine
- swollen or painful glands
- tightness in the chest
- unusual bleeding or bruising
- unusual weight loss
- watery or bloody diarrhea

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

- Acid or sour stomach
- anxiety
- belching
- burning feeling in the chest or stomach
- difficulty with moving
- dry mouth
- heartburn
- hyperventilation
- indigestion
- irregular heartbeats
- irritability
- itching of the vagina or genital area
- muscle pain or stiffness
- nervousness
- pain during sexual intercourse
- pain, swelling, or redness in the joints
- redness of the skin
- restlessness
- seeing, hearing, or feeling things that are not there
- shaking
- stomach upset
- trouble sleeping
- white or brownish vaginal discharge

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Biocef side effects (more detail)

## Frequently asked questions

- What are the best antibiotics for a tooth infection?
- What is the best antibiotic to treat strep throat?
- Cephalexin - can this be used to treat an abscess in the mouth or gum infection?
- If people are allergic to amoxicillin can they take cephalexin?
- Can you take cephalexin for a spider bite?
- Can you take antibiotics while pregnant?
- Cephalexin - is this a drug that can be abused by teens?

## More about Biocef (cephalexin)

- Check interactions
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: first generation cephalosporins
- Breastfeeding

### Patient resources

#### Other brands

Keflex

### Professional resources

- Prescribing Information

### Related treatment guides

- Acne
- Bacterial Endocarditis Prevention
- Bacterial Infection
- Bladder Infection

## Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer