Triferic AVNU Advanced Patient Information - Drugs.com

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# Triferic AVNU (Intravenous)

Generic name: ferric pyrophosphate citrate (intravenous route) [ FER-ik-pye-roe-FOS-fate-SI-trate ]
Drug class: Iron products

Medically reviewed by Drugs.com. Last updated on Aug 27, 2022.

## Commonly used brand name(s)

In the U.S.

- Triferic AVNU

## Uses for Triferic AVNU

Ferric pyrophosphate citrate injection is an iron replacement product that is used to treat iron deficiency anemia (not enough iron in the blood) in patients with dialysis dependent chronic kidney disease (CKD).

Iron is a mineral that the body needs to produce red blood cells. When the body does not get enough iron, it cannot produce the number of normal red blood cells needed to keep you in good health. This condition is called iron deficiency (iron shortage) or iron deficiency anemia.

This medicine is to be given only by or under the direct supervision of a doctor.

## Before using Triferic AVNU

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

### Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

### Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of ferric pyrophosphate citrate injection in the pediatric population. Safety and efficacy have not been established.

### Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ferric pyrophosphate citrate injection in the elderly.

### Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

### Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

- Baloxavir Marboxil
- Bictegravir
- Dimercaprol
- Eltrombopag
- Erdafitinib
- Magnesium Sulfate
- Raltegravir

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

- Delafloxacin
- Minocycline
- Zinc

### Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

- Phytic Acid Containing Food

### Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

- Anemia that is not caused by iron deficiency or
- Iron overload—Use is not recommended in patients with these conditions.

## Proper use of Triferic AVNU

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins.

Detailed Triferic AVNU dosage information

## Precautions while using Triferic AVNU

It is very important that your doctor check you closely while you are receiving this medicine. Blood tests may be needed to check for unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, swelling of the face, tongue, and throat, trouble breathing, or chest pain after you receive the medicine.

Make sure your doctor knows if you are also using other iron supplements. Also, tell your doctor if you have had an allergic reaction to injectable iron products.

## Triferic AVNU side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

- Blurred vision
- confusion
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- sweating
- swelling of the hands, ankles, feet, or lower legs
- trouble breathing
- unusual tiredness or weakness

Less common

- Bladder pain
- bloody or cloudy urine
- difficult, burning, or painful urination
- fever
- frequent urge to urinate
- lower back or side pain

Rare

- Cough
- difficulty swallowing
- dizziness
- fast heartbeat
- hives, itching, or skin rash
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- tightness in the chest

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

- Back pain
- headache
- muscle spasm
- pain in the arms or legs

Incidence not known

- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Triferic AVNU side effects (more detail)

## More about Triferic AVNU (ferric pyrophosphate)

- Check interactions
- Side effects
- Dosage information
- During pregnancy
- Drug class: iron products
- Breastfeeding

### Patient resources

#### Other brands

Triferic

### Professional resources

- Prescribing Information

### Related treatment guides

- Anemia Associated with Chronic Renal Failure

## Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer