Cruz Azul
Cruz Azul was also the first CONCACAF team to reach the final of the Copa Libertadores , the most prestigious club competition in South American football ( which invited top Liga MX clubs from 1998 to 2017 ) , losing on penalties to Argentine football giants Boca Juniors in 2001 . 
<triplet> 2001 <subj> Copa Libertadores <obj> sports season of league or competition <subj> Boca Juniors <obj> winner <subj> 2001 <obj> point in time