Glycoside hydrolase family 89
Alpha-N-acetylglucosaminidase is a lysosomal enzyme required for the stepwise degradation of heparan sulphate . Mutations on the alpha-N-acetylglucosaminidase ( NAGLU ) gene can lead to Mucopolysaccharidosis type IIIB ( MPS IIIB; or Sanfilippo syndrome type B ) characterised by neurological dysfunction but relatively mild somatic manifestations . 
<triplet> Sanfilippo syndrome <subj> Mucopolysaccharidosis <obj> subclass of