Human interactions with microbes
Novelists have exploited the apocalyptic possibilities of pandemics from Mary Shelley's 1826 "The Last Man" and Jack London's 1912 "The Scarlet Plague" onwards . 
<triplet> Mary Shelley <subj> The Last Man <obj> notable work <triplet> The Last Man <subj> Mary Shelley <obj> author <subj> 1826 <obj> publication date <triplet> The Scarlet Plague <subj> Jack London <obj> author <subj> 1912 <obj> publication date