Nubia
It was the seat of one of the earliest civilizations of ancient Africa , the Kerma culture , which lasted from around 2500 BC until its conquest by the New Kingdom of Egypt under Pharaoh Thutmose I around 1500 BC , whose heirs ruled most of Nubia for the next 400 years . 
<triplet> Kerma culture <subj> Africa <obj> continent <triplet> Thutmose I <subj> New Kingdom of Egypt <obj> time period <subj> Pharaoh <obj> position held