Macrophage migration inhibitory factor domain
The MIF homologue D-dopachrome tautomerase ( EC 4 . 1 . 1 . 84 ) is involved in detoxification through the conversion of dopaminechrome ( and possibly norepinephrinechrome ) , the toxic quinine product of the neurotransmitter dopamine ( and norepinephrine ) , to an indole derivative that can serve as a precursor to neuromelanin . 
<triplet> dopamine <subj> neurotransmitter <obj> instance of