Fumarase deficiency
Fumarase deficiency ( or fumaric aciduria ) is an exceedingly rare autosomal recessive metabolic disorder in Krebs cycle characterized by a deficiency of the enzyme fumarate hydratase , which causes a buildup of fumaric acid in the urine , and a deficiency of malate . 
<triplet> Fumarase deficiency <subj> metabolic disorder <obj> subclass of <triplet> fumarate hydratase <subj> Krebs cycle <obj> biological process <triplet> fumaric acid <subj> Krebs cycle <obj> part of