Inhibitors/ competitors of active renal elimination pathway Cimetidine reduced the renal clearance of pramipexole by approximately 34%, presumably by inhibition of the cationic secretory transport system of the renal tubules.
34% - kal csökkenti a pramipexol renalis clearance- ét, mégpedig minden bizonnyal a vesetubulusok kationos szekréciós transzportrendszerének gátlásával.