Gravely concerned that the drug problem, despite increasing efforts by States, relevant international organizations, civil society and non-governmental organizations, is still a challenge of global dimensions which constitutes a serious threat to the health, safety and well-being of all humankind, in particular young people,
严重关切尽管各国、有关国际组织、民间社会和非政府组织继续加紧努力，但毒品问题仍然是一项全球性的挑战，严重威胁全人类，特别是青年的健康、安全和福祉，