In addition to these few empirical studies, there are numerous anecdotal reports of families using folate treatments with their children, most of which are promulgated through Internet websites and the Autism Research Institute's (ARI) publication, Autism Research Review International. For the most part, these reports are favorable. Additionally, the ARI recently published findings from their web-based investigation on the parent-reported use and efficacy of a wide range of treatments for children with AD. Of the 1437 families who indicated use of folic acid as a therapeutic supplement, 42% said their children got better, 54% said their children did not exhibit noticeable changes, and 3% said their children got worse. Taken together, these limited data support the possibility for folic acid and other folates to generate favorable outcomes among children with AD; this may hold true particularly for pre-adolescent children.