Statistical Considerations in the study design Since this will be the first human application study for nerve laceration on a novel technique, its results will be valuable in guiding future full scale studies. The rationale for proposing a total 80 subjects in this study is based on a recently completed study on using post surgical electrical stimulation to enhance nerve regeneration in patients with carpal tunnel syndrome. In that randomized controlled study, a similar sample size was used and the investigators found a significant improvement in nerve regeneration in the treatment group compared to controls. Based on motor unit number estimation, the primary outcome used, the treatment group showed a statistically significant improvement compared to the control group.