Cholera is a disease of humans affecting the small intestine where fluid and electrolyte secretion is increased while their absorptions are decreased leading to profuse watery diarrhoea. As the human colon has the capacity to absorb water and electrolyte (19), some compensation is expected reducing the diarrhoeal loss. In recent studies (20, 21) SCFAs have been shown to stimulate sodium absorption in the colon, an effect that is not influenced by c-AMP, and additionally they have been found to inhibit cyclic AMP-mediated chloride secretion in the colon.