Treatment of subjects At visit 1 ("Screening/Recruitment") all subjects are informed about the projected trial. If subjects are willing to participate, they receive periodontal screening examination (PSI) and medical history is asked. At visit 2 ("Baseline", consist of two appointments at intervals of 24 hours) within the first appointment, subjects are randomized and periodontal parameters are examined. The blinded packages of different dentifrices are dispensed to the subjects. At the end, the subjects receive routine supragingival scaling with sonic scalers and polishing with an air powder device (glycin powder). Subjects are instructed to abstain from oral hygiene for the next 24 hours. At the end, subjects fill out the two questionnaires. At the second appointment, plaque formation rate is examined and subjects are instructed to brush with their already used toothbrush for 2 minutes at least twice per day at home.