A recent study [Shifren, et al. 2000] has shown that transdermal continuous patch testosterone dose 150micro g or 300micro g vs. placebo daily during the 12 week study improved sexual health including desire, arousal, and orgasm frequency in women with surgically induced menopause after oophorectomy. Blood levels reached 3.0nmoles/L (5x baseline). Shrifren et al [2000] found no significant side effects with transdermal sustained testosterone treatment. Another study [Goldstat, et al. 2003] looked at transdermal testosterone given in gel, 10mg a day given for 12 weeks in a double-blind design for 31 pre-menopausal women with a mean age of 40 years. The women entered the study presenting with low sexual desire. Testosterone treatment resulted in a significant improvement in psychological general well being and sexual self rating scale. No adverse effects were reported. Blood levels of testosterone increase about 2.5 times baseline to 2.6nmoles/L.