As part of the UTSW Depression Cohort, patients will allow banking of their specimens. The study will only enroll participants comfortable with providing specimens. Of course, like with any other study procedure, those not comfortable with providing specimens will not be enrolled in this study. Specimens which are banked may include blood or blood products, urine, stool samples, tissue samples, saliva or clinical waste products. Clinical waste products include surgical waste tissue samples, placenta samples and biopsy samples. Once a sample is collected, all identifying information will be removed, and it will be given a unique code. The information linking this unique code to a patient's identifying information will be stored in the master log. Samples will be stored appropriately in the CDRCC freezers located in the north campus building of UT Southwestern. Samples will be overseen by CDRCC research personnel. A sample will be stored indefinitely until the sample runs out or it is destroyed.