Expected results and significance of the project Project results will be used as background for establishing recommended procedure of antibiotic prophylaxis administration in surgery. Standardized protocol will be introduced for patients monitoring including monitorzation of nosocomial infections which is can be applied in general surgical praxis. Simple universal software will be created in terms of study which manages patient database and thus enables rapid concurrent assessment of health care quality. Respective reduction of nosocomial infections frequency should result in significant economic benefit for surgical praxis. With regard that similar complex prospective study has not been published in national and international magazines, publication in impact journal; socioeconomic analysis will be published especially in national medical journals so it would be easily accessible.