- The subject has received any other prescription or non-prescription medication (with the exception of nonprescription-strength ibuprofen and acetaminophen, topical non-steroidal preparations, and topical hydrocortisone (up to 1% strength)) or dietary or herbal supplement within 30 days or 5 half-lives (whichever is longer) prior to the first dose of study drug, without the approval of both the Investigator and Sponsor.