Process Written consent will be signed. No sedative premedication will be prescribed. The patients will be fasted for 6 hours before the procedure. Then patients will be sent to the endoscopy room about 1 hour before the procedure. A nasal catheter is positioned to deliver oxygen if oxygen is needed. Vital signs including heart rate, blood pressure, SpO2 and respiratory rate will be recorded. After obtaining baseline hemodynamic data (NIBP, HR) and respiratory data (SpO2, RR), the patients will be asked to evaluate their baseline levels of anxiety using a numerical rating scale.