8. Meet both screening criteria on clinically-performed cardiopulmonary exercise testing within 12 months. Peak VO2 ≤60% age/sex-adjusted normal value + peak respiratory exchange ratio (RER) ≥1.05 One of the following: NT-proBNP ≥400 pg/mL or NT-proBNP <400 pg/mL, with rest PCWP >20 mmHg and/or >25 mmHg with exercise