Before recruitement, the guardian will be informed about the aims, character and risks of the study using the information text in the Subject Information (Appendix 1). After the subject has had sufficient time to acquaint himself with the information text, the investigator seeks for his written consent (Appendix 2). The original signed consent form will be retained by investigator. The investigator is responsible for informing all study team members of sufficient details of the study and the methods to be applied.