- After consenting, the patients will be offered to come for weekly injections of 17-alpha Hydroxyprogesterone Caproate (250 mg) or placebo given by a study nurse. If they cannot come for weekly injections, they will be handled the medications at the time of their follow up visits to their obstetricians to be given by a private nurse, whichever is more convenient for them. In order to avoid the burden on the clinic staff, it was decided to use the OPD premises from 11:30 a.m. to 1:30 p.m., a time where OPD sessions are over. Flow sheets to document the date of the injection will be available with the RA, obviating the need for pulling out patients charts. The financial compensation of the staff-nurse will comply with AUMBC rules and regulations.