The pharmacologic treatments for migraine headaches are typically divided into abortive therapies and prophylactic therapies. The abortive therapies are usually divided into nonspecific medications used to treat migraines: analgesics/NSAIDS (acetaminophen, aspirin, ibuprofen, naproxen sodium, ketorolac), and narcotic analgesics (meperidine and butorphanol), adjunctive therapy (metoclopramide, prochlorperazine). Migraine specific abortive therapies include ergotamine derivatives (ergotamine, caffeine plus ergotamine, dihydroergotamine) and the Triptans (Sumatriptan, Naratriptan, Rizatriptan, and Zolmitriptan) (Aukerman, 2002). Unlike the abortive therapies, which are taken to treat an existing headache, prophylactic therapies are taken (usually daily) to reduce the frequency and intensity of migraine headaches. Prophylatic, or preventive medications are generally divided into the first-line agents and second-line agents. First-line therapies for migraine prophylaxis in adults include propranolol (Inderal), timolol (Blocadren), amitriptyline, divalproex (Depakote), sodium valproate, and topiramate (Topamax) (Modi & Lowder, 2006). Agents that could be used as second-line therapy for migraine prophylaxis in adults (listed by evidence of effectiveness) include gabapentin (Neurontin), naproxen (Naprosyn) or naproxen sodium (Anaprox), timed-release dihydroergotamine mesylate (DHE-45), candesartan (Atacand), lisinopril (Zestril), atenolol (Tenormin), metoprolol (Toprol XL), nadolol (Corgard), fluoxetine (Prozac), verapamil (Calan), magnesium, vitamin B2 (riboflavin), coenzyme Q10, hormone therapy (estradiol topical gel [Estrogel]), and botulinum toxin type A (Botox) injections (Modi & Lowder, 2006).