Patient follow up Physiological variables (hemodynamics gas-exchange, and respiratory mechanics) and medication will be recorded within 2 hours before study enrollment and at 9 a.m. of days 1-10 following study enrollment. Organ dysfunction according to the Sequential Organ Dysfunction Assessment score and clinical course complications will be documented until day 60 post-enrollment. Lastly, the final outcome (i.e. survival to hospital discharge or in-hospital death) will also be recorded.