A single oral dose of each medication will be administered to each participant with a 48 hour washout period between administrations. Serial blood samples will be obtained at the following times after the administration of the nicotine dosage forms: 0, 4, 8, 10, 12, 16, 30, 45, 60, 90, 120, and 180 minutes. Vital signs will be obtained prior to dosing and at 30, 60, 180, and 240 minutes after dosage administration. A craving questionnaire will be administered prior to dosing and at 5, 11, 17, 25, 35, 50, and 65 minutes. Craving questionnaires will then be administered at 30 minute intervals thereafter up to 180 minutes after medication administration. A Product Preference Questionnaire will be completed at the end of the second study period. A 30 day follow-up visit will be scheduled with each participant at the conclusion of the study