If it is necessary to withdraw a patient during the treatment phase, administration of the study drug will be discontinued. If the patient is still parasitaemic, quinine will be given as a rescue therapy unless there are clinical reasons to use another drug. For withdrawals outside the treatment phase the team will carry out all the safety and efficacy assessment measurements that would have been carried out at the next scheduled visit and the same will apply at delivery (unless the patient is lost to follow up).