9 Clinical evidence or history (including that from medical and medication history, physical examination, laboratory, ECG and any other available test results such as those from medical imaging studies) of significant cardiovascular, respiratory, renal, gastrointestinal, hematologic (eg, anemia), neurologic, psychiatric conditions or of any disease that may interfere with the objectives of the study or with the subject successfully completing the study 10 Presently taking prescription or over the counter medication including products containing acetaminophen, vitamins, herbs or dietary supplements, which cannot be discontinued. Prohibited medications must be discontinued at least 7 days prior to check-in and all other medications and supplements must be stopped at least 72 hours prior to check-in.