Ten patients with HCV proven by PCR, not on treatment, will be recruited from the VA GI clinic patient population. Background data will be gathered from the charts and by a questionnaire. Blood for baseline liver function tests including serum ferritin, serum isoprostane, serum aconitase, plasma glutathione (GSH), glutathione peroxidase (GPx) and total antioxidant status (TAS), will be obtained in all patients. These tests will be repeated in each patient after 15 days and 1 month of NAC at 1000 mg by mouth twice a day. Tests will again be repeated 30 days after stopping the study medication. Hep c mRNA will be measured at baseline and at 30 days. The research protocol will be explained to the patient and informed consent will be obtained prior to enrollment. For the volunteers travel expenses and time, $25 will be given at the beginning and end of the study for participation.