After written informed consent is obtained and subjects are admitted into the study, participants will be randomized to one of two groups, buffered lidocaine or non-buffered lidocaine. Randomization lists will be computer generated with a one-to-one allocation ratio in blocks by the WIH pharmacy staff. After signing the consent form, each participant will be assigned a study ID number corresponding with the order of recruitment into the study. The pharmacy will prepare identical syringes containing 9 ml of the 1% lidocaine + 1 ml of sodium bicarbonate or 10 ml 1% lidocaine labeled only with the study name and sequentially numbered. The numbered syringe corresponding with the participant's study ID number will be obtained by the study staff from the locked refrigerator in the Women's Primary Care Center or The Program In Women's Oncology. The syringes will appear identical. Participants, study personnel, the medical assistant, and the clinician will be blinded to the assignment.