This was followed by a double blind, randomised controlled trial comparing magnetically assisted capsule endoscopy (MACE) with conventional upper gastrointestinal endoscopy to detect coloured beads in a porcine stomach model. Gastroscopy correctly identified 88% (79/90) beads, MACE correctly identified 89% (80/90) beads and thus is noninferior to gastroscopy in this setting (95% CI 82.76%-95.24%). Mean examination times for gastroscopy and MACE were 3.34 minutes and 9.90 minutes respectively. Clearly there are significant differences between a porcine model and live human stomach. However, these studies provide proof of the principle that a small bowel capsule endoscope can be manipulated to make targeted movements within the stomach. We now also have one completed human trial assessing whether the magnetic controller can be utilised to manipulate the small bowel capsule through the stomach into the duodenum to improve the completion rate of small bowel capsule examinations. Another trial is also near completion comparing the diagnostic ability ,within the stomach, of MACE compared to conventional gastroscopy in the context of recurrent iron deficiency anaemia.