Safety Safety evaluations will include measurement of vital signs during and immediately after (for 2 hours) the infusion of study medications and assessment of adverse events (AEs) at each of the evaluation visits. Additional vital signs and lung function measurements will be performed immediately after each infusion and at t = 1 and 2 hours post dose. Routine laboratory tests will be performed at screening, at day -1 and at weeks 2, 6, 8 and 12. During the study, the medical monitor will regularly review safety data.