- However, at Week 12, subjects on placebo who have not achieved a 20% improvement in swollen joint count(SJC66) and tender joint count (TJC68) will be re-randomized (automatically via interactive voice/web response [IXRS]) to treatment to receive GLPG0634 100 mg q.d. or 50 mg b.i.d. doses in a blinded fashion, subjects on 50 mg q.d. who have not achieved a 20% improvement in SJC66 and TJC68 will be assigned to 100 mg q.d. and subjects on 25 mg b.i.d. who have not achieved a 20% improvement in SJC66 and TJC68 will be assigned to 50 mg b.i.d. All will continue the study until Week 24.