If we find in this preliminary study that texture features change during antiresorptive therapy, future studies will be designed to examine these changes more precisely. With the results of the present study we will know what magnitude of change in texture analysis to expect during therapy and will be able to accurately calculate the sample size to further study these changes. Most interestingly, however, we will be to compare texture analysis during therapies with different pharmacological agents. Specifically, comparing an anabolic agent such as PTH to antiresorptive therapies such as biphosphonates and estrogen may provide important information about the mechanism of action and timing of effects on the bone structure for different agents.