This analysis is consistent with the results of the latest RCT recently reported by Shechter and colleagues. They randomized 194 patients with acute MI considered unsuitable for thrombolysis to control (N=98) or intravenous magnesium (N=96). In addition to the standard contraindications to lytic therapy, reasons for exclusion from thrombolysis included either presentation after six hours and/or age greater than 70 years.