1. Stage 1: Treatment Engagement and Detoxification (week 1-2). In our pilot study some addicts had difficult sitting still for 15-mins meditation with eyes closed, but they could do breathing exercise with eyes open. In this study we will use 6 breaths/minute as near resonant-frequency at the beginning of IM training. Each subject will receive a MP3 player with customized RFB guiding program that include waving sound (audio) and moving bar (visual) to assist the subject to do RF breathing. The subject is required to do abdominal RFB at least 15 min per day open-eye in the first week, and close-eye in the second week, then gradually switching to a combination of RFB and IM.