In 2011, the results from another RCT were published, comparing vaginal misoprostol insert of 100, 150 and 200 mcg. It was found that the 200 mcg group delivered within 25,8 hours for nulliparous, and 14 hours for multiparous women. The rate of CS was increased in this group, due to affected fetal heart-rate, although not significant. There were no differences in neonatal outcome. Tachysystoli (hyper-stimulation) was more frequent, but fewer needed to be stimulated with oxytocin (49%).