Finally, Pentax released a new high definition endoscopy system in 2007, the I-scan system, which also allows post hoc modification of the images. On the one hand, surface enhancement enables to better highlight mucosal changes. Spectral modification allows to apply different modes in analogy with to FICE system. For instance the p-mode for pattern recognition helps to accentuate epithelial features. The TE-mode helps to assess the vasculature of the gastrointestinal mucosa. Recently new filters were developed such as the colon mode, specifically designed for the colon. In one study VC with I-scan TE-mode was compared to CE and standard white light endoscopy in 69 patients. In both the VC and CE mode 11 dysplastic lesions were found (Hoffman et al 2010). Data about the improvement of detection of dysplasia are lacking until now.