Participants: Twenty subjects with clinically definite MS and objectively documented new learning impairment will be included in the study. Subjects will be excluded from participation in the presence of significant language comprehension deficits. Additional exclusion criteria are as follows: age greater than 60, less than 1-month post most recent exacerbation, current treatment with corticosteroids, significant neurological history aside from MS (e.g. epilepsy, TBI), significant substance abuse history as documented by the MAST,27 significant psychiatric history (e.g. Schizophrenia, Bipolar Disorder, Major Depression), non-fluency in the English language.