Laboratory data suggests that a rapid intravenous infusion of cold fluid during CPR effectively decreases core temperature. Nordmark et al. studied the induction of hypothermia with a large volume of intravenous ice-cold fluid after cardiac arrest during CPR in anaesthetised piglets who were subjected to eight minutes of VF. The mean temperature reduction was 1.6°C in the hypothermic group and 1.1°C in the control group (p=0.009).