One randomized controlled study published in 2008, compared vaginal insert of 50 and 100 mcg misoprostol to vaginal insert of 10 mg Dinoproston. The two primary outcomes were the duration from administration to delivery, and the frequency of caesarean sections (CS). It was found that 100 mcg misoprostol and 10 mg dinoprostone had about the same duration from start of induction to delivery, whereas 50 mcg misoprostol showed a prolonged duration. The frequencies of CS were the same.