Our project team has extensive experience with the practical implementation of clinical controlled studies and analytical methodology linked to registries and health economic cost estimates. From this study we expect increased knowledge of whether clinical outcomes from exercise therapy may be related to exercise dosage and how exercise therapy need to be individualized according to the patient's history, clinical picture and coping strategies obtaining. In a recent report from the Swedish Council on Health Technology Assessment (SBU) they requested such data evaluating both the effects of exercise treatment analyzes that support personalized rehabilitation.