MOVING BEYOND THE CURRENT STATE OF THE ART This project aims to move beyond the state-of-the-art by studying association between macro- and microvascular structure and function in children (8-13 years) born prematurely (extremely low birth weights, ELBW, i.e. birth weight below 1000 grams), and sex- and age-matched controls. The specific strengths hereby are that this ELBW cohort has been well characterized on its perinatal aspects [George et al.]. The characterization in the postnatal period includes biometry, perinatal characteristics (e.g. Apgar score, drugs, respiratory support), creatinine trends in the first 6 weeks of postnatal life and psychomotor development (Bayley Scales of Infant Development) at the age of nine months and two years.