Patients who require ongoing clinical care will continue to be followed by their treating psychiatrist following completion of the study protocol. This process will provide a database through which patient characteristics at the time of initial presentation may be examined in relation to the onset and course of illness, prognosis, and response to various forms of treatment. While some of these factors have been examined in previous studies, little information is available on patients who are treatment naive at time of study entry. This project seeks to explore these issues and to provide a basis for further research in the area of first episode mood disorders.