The Fujinon Intelligent Chromo-Endoscopy (FICE) system uses a similar theoretical principal as NBI but this is achieved via the use of post hoc computer algorithms, applying different filters to the stored endoscopic images and enabling a theoretically endless number of combinations of filters that can be used. Currently 10 different spectrum filters can be used. There are predefined settings for visualization of the colonic mucosa. There are no previous data comparing white light endoscopy and FICE in the detection of dysplasia in longstanding ulcerative colitis.