We collect a sample of blood/plasma and have a repository (blood) and for future analysis. After noting that subject has consented to main study as well as consenting to have his blood stored for later research purposes, appropriate research staff will direct the phlebotomist to draw and additional tube of blood (approximately 7mls of blood) into a purple cap (EDTA) tube. After processing, each sample will be securely stored at the participating site under appropriate conditions .