Weight loss is affected by multiple perceptions and behaviors, such as perceptions of overweight, physical activity, dietary habits, smoking, and alcohol use. Although past epidemiological research has investigated the independent effects of such influences on weight, research to date has not identified whether distinct clusters of weight perceptions and behaviors exist among overweight adults. Given that such clusters may differ by sociodemographic characteristics, identifying clusters may contribute to the design of innovative and tailored weight-loss interventions that address the presence of multiple influences on weight loss and increase the likelihood of successful interventions.