- Corrected QT interval ≤ 450 msecs (≤ 480 msecs if recommended MTT has no known effect on QT interval) on screening ECG, within 14 days prior to C1D1 I10. Life expectancy of at least 4 months I11. Specific toxicities related to any prior anti-cancer therapy must have resolved to grade ≤1 except for alopecia and fatigue. Grade 2 neutropenia or anemia is accepted.