Histopathological procedures Routine hematoxylin and eosin (HE) stain of the biopsies will be performed, and evaluated according to Gleason system (gold standard for histological evaluation) ranging from 1-5, with 5 being the most aggressive tumour. Gleason score is the sum of the two dominating Gleason grades, for instance 5+5 for the most aggressive tumour giving a Gleason score of 10. The biopsies will be marked, in order to evaluate the spatial distribution of cancer.