7. Abnormal organ function is permitted. However, patients must have absolute neutrophil count >/= 1000/mL; platelets >/= 75,000/mL; creatinine < 1.5 mg/dl in males and < 1.4 in females;T. Bilirubin </= 3 X upper limit of normal (ULN); AST(SGOT) and/or ALT(SGPT) </= 2 X ULN