2.3 EXCLUSION CRITERIA FOR ENROLLMENT - severe malaria requiring hospitalization, severe malnutrition (weight-for-age ≤ 3 standard deviations below the mean), co-infection with any other Plasmodium species, severe anemia (Hg<8g/100 ml), hypersensitivity to CQ or PQ, febrile conditions caused by diseases other than malaria, serious or chronic medical condition, pregnant or breastfeeding women, prior history of hemolysis or severe anemia or regular medication which may interfere with antimalarial pharmacokinetics.