1.32 A written report will be submitted within 7 working days describing any life-threatening or lethal (grade 4 or 5) known reactions (except for grade 4 myelosuppression), and any grade 2 or 3 unknown reactions. The address for submitting ADR reports is: Coordinate Center of TCOG, National Health Research Institutes in Biomedical Science, Academia Sinica, Taipei, Taiwan.