The study was renewed in the year 2000 under R01HL23727 to conduct a population survey of 4,000 adults, ages 25 to 84 in 2000-2002, to detect current trends in cardiovascular disease risk factors, including serum lipids, blood pressure, cigarette smoking prevalence, dietary fat intake, obesity, diabetes, physical inactivity, fibrinogen, and serum vitamin E. Cohort and ecological analyses will be used to link secular trends in risk factors to morbidity and mortality from coronary heart disease, congestive heart failure, and stroke. A total of 1,000 children and adolescents, ages 8-17, will also be surveyed using youth-specific measurement instruments where appropriate.