This study suggested that it may be possible to give transdermal testosterone 4-8 hours before intercourse in couples where the female partner suffers from low sexual interest or desire and /or difficulties in arousal, but where the couple is able to plan intercourse several hours in advance, which is possible in many couples, based on our clinical experience. In such couples androgen could be given on a prn basis and the possibility of side effects with long term use greatly reduced. We therefore propose such a study.