Introduction High left ventricular filling pressure (LVFP) have been associated with volume overload in patients with heart failure and have also been correlated to some extent with more severe symptoms and lower survival rates. In a study of more than 1000 patients hospitalized with acute decompensated heart failure, those with persistently elevated LVFP more than 18 mmHg had increased 1-year mortality compared with those with LVFP less than 16 mmHg. Investigators have also demonstrated that acute reduction of LVFP with vasodilator therapy can improve cardiac function and reduce mortality risk, suggesting that LVFP is an appropriate marker of cardiac risk and functional improvement. However, LVFP measurement involves invasive catheterization, limiting its clinical use especially in the outpatient setting. In advance of new techniques and modality, echocardiography provides some useful parameters to assess LVFP, such myocardial tissue Doppler imaging. Many articles had documented that peak velocity of early-diastolic trans-mitral inflow velocity divided by early-diastolic velocity over mitral annulus was closed correlated with LVFP. However, myocardial tissue Doppler only provides the information of regional myocardium, so patients with regional wall motion abnormality, such as coronary artery disease, can't be assessed by this method without handicap. In addition, conduction disturbance, like bundle branch block, also influences the result of myocardial tissue Doppler. For resolving those problems, we will design a new global parameter to assess LVFP. In prior study, we disclosed the logarithmic relationship between LVFP and left atrial distensibility in acute myocardial infarction patient received primary coronary intervention. This time, to extend our conclusion to general population received echocardiographic examination is attempted. Additionally, we infer that left atrial distensibility which indicates LVFP would influence long-term prognosis, including the event rate of cardiovascular event, stroke and death.