Studies completed thereafter in egg-allergic children tended to demonstrate that this vaccine could safely be administered. A review of the literature of 27 studies prior to 2012 (table 1) consisting of 4172 egg-allergic patients vaccinated with TVI was published by our group[3]. Amongst these patients, no cases of severe allergic reactions were observed. The most common observed allergic reactions were mild (local erythema, local or distal urticaria, mildly wheezy breathing), though 1 patient did present generalized urticaria.