Study design The patients were treated with levothyroxine (Eltroxin, Glaxo) at a starting dose of 50 mcg per day. The follow up was conducted in the Research and Development unit, Assaf Harofeh Medical Center at 1, 4 and 7 months post dosing. In patients who did not achieve normalization of TSH, the dose of levothyroxine was increased to 100 mcg per day.