Therefore, the general aim of this study is to enhance psychological well-being in emergency physicians. The primary objective is to verify our preliminary findings at Karasek scores on a large sample size of emergency physicians. The secondary objectives are to evaluate whether there is a change in perception of work both at short-term (on leave and after a 24-hour shift) and long-term (with professional experience). We will further explore its relationships with some biomarkers of stress and protective factors. Moreover, we aim to compare emergency health care workers specificity.