This study will be a double blinded, randomized controlled trial to be performed at the Women's Primary Care Center and The Program In Women's Oncology Clinics. Patients will be recruited as outlined below and assigned a sequential study identification number. They will be asked to complete the questions on the Data Collection Form/Survey (see form titled "Data Collection Form") and if they agree to the study, will sign the Informed Consent (see form titled "Informed Consent"). The Data Collection Form/Survey will be given to the patient upon decision to perform a vulvar biopsy by the provider. The patient will be consented by approved research personnel. Then, the patient will undergo a vulvar biopsy as per clinician protocol. Baseline pain scores will be collected using the visual analogue scale. After skin prep, the pre-filled, sequentially numbered, randomized 25 gauge syringes will be used to inject 3ml of either buffered or non-buffered lidocaine prepared by the pharmacy as outlined below. The biopsy will then proceed as per clinical standard. The patient will be presented a 100 mm visual analogue scale to mark their pain level. A total of three pain scores will be obtained as the patient marks on the pain scale when instructed: A baseline pain score prior to intervention, pain score at time of infiltration, and pain score at the completion of the biopsy. The Data Collection Form/Survey will be collected from the patient by approved research personnel and placed in secure storage. Data will be entered into a secure electronic database for statistical analysis. Nursing staff at the WPCC may be present for the biopsy, but will not be involved in the conduction of the study.