Medical education was transformed from mainly didactic class before 19th century to the clerkship and internship training based on the concept of "learning by doing" in 20th century. There are new challenges for medical education in the 21th century, including knowledge explosion, the importance of communication and teamwork in clinical care, and lack of comprehensive and systemic experiential learning. Therefore, another paradigm shift of medical education in this century is necessary. This research project, through applying high-fidelity simulation, resuscitation teamwork model, and concept of flipped classroom in resuscitation training, take the innovation and reform of resuscitation training as a pilot test for paradigm shift of medical education.