【Anticipated work schedules and results:】We estimate to enroll 2 to 3 patients per week, and it will take approximately one year to recruit sufficient number of patients. It will require 12 additional months for follow-up. Therefore, we estimate a total of three years to complete this study. We anticipate favorable results of ESWT in chronic diabetic ulcers. We also anticipate superior results with ESWT over HBO therapy. Furthermore, we anticipate the improvement in local blood flow perfusion, antibacterial effect as well as angiogenesis and tissue regeneration effects after ESWT. This novel method of treatment may bring in a new insight in the management of chronic diabetic ulcers. Shockwave has the potential to cure chronic skin ulcers without surgery and directly benefits thousands of patients who suffer from this disastrous disease.