Secondary research question 2: Are the effects of the intervention on the primary depression outcome mediated by the following: use of the self-care tools; activation; self-efficacy; or health behaviors? Using approaches developed by Van der Weele and colleagues we will estimate the extent to which overall effects on the primary outcome are mediated through changes in the mediating variables of interest. These methods, based on potential outcomes (counterfactual) theory and inverse probability weighted marginal structural models, allow estimation of the mediating effects while preserving the structure of the randomization. Briefly, a marginal structural model is built for the outcome as a function of each mediator and randomization. The controlled direct effect of the randomized intervention, i.e., the effect of intervention holding the mediator(s) constant, is easily estimable from this model, while under further assumptions the so-called "natural" indirect effect, i.e., the effect mediated through individual mediators, can also be estimated.