The Subjects with age-and education-adjusted MMSE<26 or MOCA<26 or memory and non-memory domains test score that is 1.0 Standard Deviation (SD) or more below age-education adjusted norms are evaluated by Clinical Dementia Rating (CDR) scale. Subjects with a CDR global score of 0.5 together with Sum of Boxes of ≥3 or global score of ≥1 denoting dementia undergo a structured clinical assessment including neurologic examination, laboratory tests and final review by an expert panel of neurologists and psychiatrists, for final diagnosis and sub-classification of MCI, according to an standard SLAS protocol already established for the assessment and diagnosis of MCI and dementia.