Creatinine Tranexamic acid dose < 140 µmol/L 2 mg/kg/h 140 - 290 µmol/L 1,5 mg/kg/h 291 - 580 µmol/L 1 mg/kg/h > 580 µmol/L 0,5 mg/kg/h Table: dosing of tranexamic acid according to renal function, from Nuttall and al. (8)