Technical advances in Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS) has provided researchers with the opportunity to study functional and metabolic changes of the central nervous system (CNS) in both healthy controls and individuals with neurological diseases in response to sensory, motor or cognitive stimulation. While MRI is in common usage in radiology departments and clinics MRI and MRS techniques and hardware are continually being upgraded and designed for Functional Magnetic Resonance Imaging (fMRI) and Magnetic Resonance Spectroscopic Imaging of the CNS at 3.0 Tesla. We will evaluate new sequences on volunteers and for potential use in patients with CNS pathology. These studies are required in order to develop and implement new imaging techniques for research and clinical applications.