7. Adequate organ function including: Absolute neutrophil count (ANC) >/= 1,500/ul; platelets >/= 100,000/ul; total bilirubin </= 1.5 x upper limit of normal (ULN)*; AST (SGOT) and ALT (SGPT) < 3 x ULN; calculated creatinine clearance (CrCl) > 50 cc/min (calculated using the Cockcroft and Gault formula). *In patients with known Gilbert's syndrome direct bilirubin </= 1.5 x ULN will be used as organ function criteria, instead of total bilirubin.