Statistics Statistical methods and analysis Baseline characteristics will be displayed by group (those currently receiving DPP-4 inhibitor, those currently receiving GLP-1analogue, and those currently not using DPP-4 inhibitor or GLP-1 analogue) as mean and standard deviation for normally distributed continuous variables, median and interquartile range for non-normally distributed continuous variables, and counts and percentages for categorical variables. The primary outcome (EPC) will be compared by treatment group using linear regression, with and without adjustment for potential confounders. The confounders to be considered are age, gender, ethnicity, body mass index, duration of T2DM and insulin treatment. The mean EPC and its 95% confidence interval in each of the three groups will be presented as well as the mean difference between DPP-IV vs GLP-1 treatment group and between incretin vs non-incretin treatment groups. A similar analysis will be used for all continuous secondary outcomes. Binary outcomes will be compared by groups using logistic regression analysis with and without adjustment for the same confounders. All statistical tests will be 2 sided and p<0.05 will be taken to be statistically significant.