- Active infection with human immunodeficiency virus (HIV), human T-cell lymphotropic virus (HTLV), Hepatitis B virus (HBV), hepatitis C virus (HCV) (can be pending at the time of cell procurement; only those samples confirming lack of active infection will be used to generate transduced cells) defined as not being well controlled on therapy. Patients are required to have negative HIV antibody or negative HIV viral load, negative HTLV1 and 2 antibody, negative Hepatitis B surface antigen, and negative HCV antibody or viral load.