There are currently two pediatric studies ongoing in the United States of America. DAP-PEDS- 09-01 will assess pharmacokinetics (PK) and safety of Daptomycin in 18 children ages 3-24 months with Gram-positive bacterial infections. DAP-PEDS-07-03 will assess efficacy and safety of multiple daptomycin doses in 339 children aged 2 - 17 years with skin and skin structures infections. Design and dosing of both studies are based on previous findings in two pediatric studies involving 25 children ages 2-17 years and 12 children ages 2-6 years. None of these studies will or has investigated daptomycin penetration into the CSF.