Fatigue is a complex, multi-dimensional symptom with several contributing factors. Pain, sleep disturbance, depression, decreased physical activity and menopausal symptoms are associated with fatigue (Couzi 1995, Servaes 2002, Bennett 2004 and Bower 2000). Therefore, a broad-based intervention program holds the most promise for alleviating fatigue. We propose to examine the efficacy of a holistic mind/body medicine approach to empower women to address many of the factors associated with fatigue and incorporate healthy behaviors into their routine to alleviate fatigue. The intervention is a 10 week program modeled after the Mind/Body Medicine program established by Dr. Herbert Benson of the Harvard-affliliated Mind Body Medicine Institute.