The aim of our study is to compare the efficacy of a 400-µg sublingual dose of misoprostol Cytotec® (Searle Pharmaceuticals, Bucks, United Kingdom) administered at 4-hour intervals with an equivalent dose regimen administered vaginally in women admitted for second trimester termination for intrauterine fetal death. In addition, we want to assess patient acceptability of the 2 modes of administration.