Epileptic discharges, the secondary outcome variable of this study, were recorded by a trained staff. EEG was acquired from all participants using a 32-channel, international 10-20 system of electrode placement (Neuvo, Compumedics, Australia with PerFusion EEG software). EEG was collected for 30 minutes in the awake state only. EEG was recorded as a single session at baseline, immediately, 1-, 2-, 3- and 4- weeks follow-ups. EEG data were analyzed by visual inspection. The numbers of epileptic discharges in the 30-minute recording were assessed by a practicing pediatric neurologist and clinical neurophysiologist (N.A.), who was blinded to the treatment condition. The EEGs that included as abnormal EEGs in LGS are slow spike-wave complexes at <3 Hz that occur during wakefulness. The complexes consist of a spike (duration < 70 msec) or a sharp wave (70-200 msec), followed first by a positive deep trough, and then a negative wave (350-400 msec). Paroxysmal fast rhythms (10-20 Hz) occur mainly during non-rapid eye movement sleep [30]. One slow spike-wave complex or one episode of paroxysmal fast rhythms were counted as one epileptic discharge.