Risks associated with sotalol: Therapeutic doses of sotalol range from 160 mg to 240 mg per day. Common side effects of sotalol therapy include bradycardia (13% to 16%), chest pain (3% to 16%), palpitations (14%), fatigue (20%), dizziness (20%), lightheadedness (12%), weakness (13%), dyspnea (21%), edema (8%), hypotension (6%), proarrhythmia (5%), syncope (5%), heart failure (5%), torsade de pointes (dose related; 1% to 4%), peripheral vascular disorders (3%), ventricular tachycardia worsened (1%), QTc interval prolongation (dose related), headache (8%), sleep problems (8%), mental confusion (6%), anxiety (4%), depression (4%), rash (5%), sexual side effects (3%), nausea/vomiting (10%), diarrhea (7%), stomach discomfort (3% to 6%), flatulence (2%), impotence (2%), bleeding (2%), extremity pain (7%), paresthesia (4%), back pain (3%), visual problems (5%), upper respiratory problems (5% to 8%), and asthma (2%). Rare (< 1%) side effects of therapeutic doses of sotalol include alopecia, bronchiolitis obliterans with organized pneumonia (BOOP), cold extremities, diaphoresis, eosinophilia, leukocytoclastic vasculitis, leukopenia, paralysis, phlebitis, photosensitivity reaction, pruritus, pulmonary edema, Raynaud's phenomenon, red crusted skin, retroperitoneal fibrosis, elevated liver transaminases, thrombocytopenia, and vertigo.