The group met 3 times in 2001 Grenier during the Belgian Presidency in the second half. • The ad hoc COMP Working Group on Epidemiology, Two informal meetings of the MRFG were organised under the chaired by Dr Kalle Hoppu, prepared a guidance document presidencies to discuss issues related to the mutual recognition on prevalence, in the context of the regulation on orphan procedure such as harmonisation projects and the ongoing drugs, which provides advice to sponsors on preparation of review of pharmaceutical legislation. applications.