Mean ± SD will be used for numeric data generated from our work. In each arm the mean difference in the IL-6 and IL-8 values will be calculated using paired sample t test. For between arms analysis, mean difference in the IL-6 and IL-8 values will be calculated using independent sample t test. Non-parametric statistics will be used if the data is skewed. A cut-off will be calculated for IL-6 and IL-8 separately using ROC curve analysis. Based on the cut-off, a binary logistic regression analysis will be performed to evaluate the predictive significance of the two treatment arms in reducing the levels of inflammatory markers IL-6 and IL-8. P-value of < 0.05 will be considered significant. Results will be presented in form of tables & figures. Statistical Package for the Social Sciences (SPSS), version 21 will be used for all the statistical analysis.