Phase III The total fat content subjected to the study will be extracted according to the Soxhlet protocol (ADAC,1995 ) from the flesh of 10 highly consumed fishes. Total lipid extraction was made with chloroform methanol (2:1) and according to Folich et al ,.(1957) methodology modified by Bligh and Dyer (1959). Fatty acid methyl esters (FAME) will be prepared with methanol using BF3 -MeoH complex, as catalyst, according to the method of Metcalfe et al (1966). Omega-3 fatty acid of the highly consumed fresh, cooked and dried fish muscle would be analyzed using Gas Liquid Chromatography and the tocopherol content will be analyzed using High Performance Liquid Chromatography (HPLC). These would be correlated with consumer preference of fish and CVD. The omega-3 -PUFA and Tocopherol content of all samples would be analyzed at same time. Sample of ten selected highly consumed fish species will be taken for this study. Lipid profile of randomly selected (50) CVD patients who will be selected with the help of the Batticaloa cardiology unit will be taken in our study and it will be monitored monthly for five months.