All the procedures performed in this study are normally done in the work-up of patients scheduled to have cystoscopy procedure and is considered a routine procedure for bladder cancer screening. The only procedure/treatment which is not routine is the use of HRME and LSC-HRME. Biopsy will be taken at the time of cystoscopy that involves standard of care. Images taken by HRME/LSC-HRME device will then be correlated with pathology results of the biopsied tissue. The samples will be coded and de-identified data will be sent to Dr. Rebecca Richards-Kortum laboratory for correlation.