Recruitment of patients for the pilot-study will begin primo 2013. The 2 pilot-groups will be conducted in 2013. Patient inclusion to the RCT will begin primo 2014 and end in 2015 depending on referrals. The rate of referrals is expected to be 4 patients a month. Treatment groups are expected to run during a course of approx. 2 years. In the same period the PhD student will participate in teaching, training and courses. In 2016 the last patients will be followed up, and data will be analyzed and interpreted, and papers to relevant journals will be written. Please see the enclosed time schedule for the three-year PhD program (Figure 4).