Studies in animal models have also shown that NMDA-mediated currents have a role in the production of spastic reflexes in chronic SCI (Bennett et al, 2001b). These currents have been discussed as another possible contributor to prolonged spasms in human chronic SCI as well (Norton et al, 2008). Taking these additional studies into account, an additional aim is to expand our study to include preliminary investigation of a possible contribution of post-synaptic NMDA-mediated currents to spinal neuron excitability and hyperexcitable reflexes in chronic SCI.