Studies completed in rats have demonstrated that ingestion of bifidobacteria can suppress aberrant crypt foci (early preneoplastic lesions) formation in the colon (Kulkarni N and Reddy B. Proc Soc Experim Biol Med 1994;207:278-283) in addition to significant decreases in colon tumor incidence and in the numbers of tumors present (Singh J et al. Carcinogenesis 1997;18:833-841).