Neutropenic patients with culture-negative fever receive a combination of gentamicin, cefazolin and piperacillin, as a first line antibiotic protocol. Persisting fever are treated with amikacin and tazocin as a second line protocol, while meropenem and vancomycin are used as the third line protocol. In cases of persistent fever not responding to antibiotic therapy within 5 days, amphotericin B (0.7 mg/kg/d) is added until the neutropenia resolves. No antifungal prophylaxis will be given.