Adverse reactions encountered most often are as follows: very common (≥ 1/ 10), common (≥ 1/ 100, < 1/ 10), uncommon (≥ 1/ 1,000, < 1/ 100), rare (≥ 1/ 10,000, < 1/ 1,000), very rare (< 1/ 10,000, including isolated cases), frequency not known (cannot be estimated from the available data).