• management and follow-up of marketing authorisation applications under the centralised procedure • provided scientific advice • provided support to the Committee for Proprietary Medicinal Products, Committee on Orphan Medicinal Products and to protocol assistance • continued supporting pharmacovigilance and post-marketing maintenance of authorised medicinal products • managed Community referrals and arbitrations arising from the mutual recognition procedure • provided support to European and international harmonisation activities of the CPMP and its working parties • provision of support to the Mutual Recognition Facilitation Group