The CHMP issued a positive opinion, on 21 April 2005, recommending the harmonisation of the SPC for Calcium Sandoz Effervescent tablets, 500/ 1000 mg and associated names for the following agreed therapeutic indications: -Prevention and treatment of calcium deficiency -Calcium supplement as an adjunct to specific therapy in the prevention and treatment of osteoporosis -Rickets and osteomalacia, in addition to vitamin D3 therapy