In the absence of data in patients with hypercholesterolaemia associated with a triglyceride level of more than 4 mmol/ L (3.5 g/ L) or more than 5 mmol/ L (4.45 g/ L) after following a diet for 4 or 8 weeks, in the CARE and LIPID studies, respectively, the benefit of treatment with pravastatin was not established in this type of patients.