- Hematology parameters: white blood cell (WBC) at least 2500/mm3; neutrophil count at least 2,000/mm3; platelet count at least 100,000/mm3; and hemoglobin at least 10g/dL. Other laboratory parameters: total serum bilirubin not exceeding 2 times institutional upper limit of normal (ULN); AST not exceeding 2 times ULN; ALT not exceeding 2 times ULN; alkaline phosphatase not exceeding 2 times ULN; and serum creatinine not exceeding 2 times ULN. In borderline cases, inclusion into the study is left to the judgment of the principal investigator.