Stocrin has been studied in three main studies involving over 1,100 adults:  in the first study, Stocrin in combination with lamivudine and zidovudine or with indinavir (other antiviral medicines) was compared with the combination of indinavir, lamivudine and zidovudine;  the second study compared Stocrin in combination with nelfinavir and two other antiviral medicines with the same combination without Stocrin;  the third study compared adding Stocrin or placebo (a dummy treatment) to a combination of antiviral medicines that included indinavir and two other antiviral medicines, in patients who had already been receiving treatment for HIV infection.