Saquinavir/ ritonavir saquinavir AUC ↔ 0.95 (0.64-1.42) 1,000/ 100 mg b. i. d. saquinavir Cmin ↓ 0.80 (0.46-1.38) saquinavir Cmax ↔ 1.00 (0.70-1.42) etravirine AUC ↓ 0.67 (0.56-0.80) etravirine Cmin ↓ 0.71 (0.58-0.87) etravirine Cmax ↓ 0.63 (0.53-0.75)