b) The following adverse event listing is based on reports from clinical trials (table 1, adverse events and laboratory abnormalities) and from the post marketing surveillance (table 2, reporting rates based on spontaneous adverse drug reaction reports classified as very common ≥ 1/ 10, common ≥ 1/ 100 to < 1/ 10, uncommon ≥ 1/ 1,000 to < 1/ 100, rare ≥ 1/ 10,000 to < 1/ 1,000, very rare < 1/ 10,000) of Betaferon use.