The design of this study is a randomized controlled trial with an intervention period of six months and a biomechanical analysis of running pattern the day of inclusion in the study. Running footwear is provided by a renowned sport equipment manufacturer working in close collaboration with the Sports Medicine Research Laboratory (SMRL) of the Luxembourg Institute of Health (LIH), which in turn is responsible for the management and execution of the study. Random allocation of the study shoes, recruitment and follow-up of the participants, biomechanical testing, as well as data management and analysis will be carried out by the SMRL. The study design is based on the comparison between 2 running shoe prototypes, which only differ with respect to the cushioning (i.e. stiffness). The cushioning properties of both shoe versions will be within the range of values of models available on the market.