Each promotion centre will be assigned with secured logons to the database and only the health professional assigned to the study, will get logons and will only be able to see the patients included in the study at their promotional centre. The scientific members have access to the secure database and data from all the included patients. All data will be secured in the database and a bag up of all the data is stored in an extern hard disk which is also secured. It is possible to track all logons to the database as well as all tasks done in the database.