Immune system disorders Rare: swelling of the limbs and face (peripheral oedema, facial oedema), sudden swelling of the face or throat with difficulties in breathing and/ or itching and rash, often as an allergic reaction (angioneurotic oedema), allergic reactions, fever due to the administration of the medicine, serious allergic reaction which causes difficulty in breathing or dizziness (anaphylactic reaction) Very rare: a life-threatening condition characterised by a sharp drop in the blood pressure, paleness, restlessness, weak/ quick pulse, clammy skin, dizziness as a result of severe allergy to this medicine (anaphylactic shock), itching rash, fever, joint swellings, muscle pains, rash (symptoms similar to those occurring in a disease called serum sickness)