When 1000mg paracetamol was given with 10 µg BYETTA (0 h) and 1h, 2h and 4h after BYETTA injection, paracetamol AUCs were decreased by 21%, 23%, 24% and 14% respectively; Cmax was decreased by 37%, 56%, 54% and 41%, respectively; tmax was increased from 0.6h in the control period to 0.9h, 4.2h, 3.3h, and 1.6h, respectively.