STOP taking Xeloda immediately and contact your doctor if any of these symptoms occur: • Diarrhoea: if you have an increase of 4 or more bowel movements compared to your normal bowel movements each day or any diarrhoea at night. • Vomiting: if you vomit more than once in a 24-hour time period. • Nausea: if you lose your appetite, and the amount of food you eat each day is much less than usual. • Stomatitis: if you have pain, redness, swelling or sores in your mouth. • Hand-and-foot skin-reaction: if you have pain, swelling, and redness of hands and/ or feet. • Fever or Infection: if you have a temperature of 38°C or greater, or other signs of infection. • Chest pain: if you experience pain localised to the centre of the chest, especially if it occurs during exercise.