Treatment and prevention of flea infestations (Ctenocephalides spp.); kills adult fleas, eggs and larvae; use as part of a treatment strategy for flea allergy dermatitis; may aid in the control of existing environmental flea infestations in areas to which the animal has access; treatment of adult roundworms (Toxocara spp.); prevention of heartworm disease (Dirofilaria immitis); treatment of biting lice (Felicola subrostratus (cats) and Trichodectes canis (dogs)); treatment of ear mites (Otodectes cynotis).