In clinical studies, the most common side effects with Sutent (seen in more than 1 patient in 10) were anaemia (low red blood cell counts), neutropenia (low white blood cell counts), thrombocytopenia (low blood platelet counts), hypothyroidism (underactive thyroid gland), decreased appetite, taste disturbance, headache, hypertension (high blood pressure), epistaxis (nosebleeds), diarrhoea, nausea (feeling sick), vomiting, stomatitis (inflammation of the lining of the mouth), dyspepsia (heartburn), abdominal (tummy) pain or distension (bloating), constipation, glossodynia (burning or tingling sensation around the mouth), flatulence (gas), oral (mouth) pain, dry mouth, yellow skin or skin discoloration, palmar-plantar erythrodysaesthesia syndrome (swelling and numbness of the palms and soles of the feet), hair colour changes, rash, dry skin, alopecia (hair loss), pain in the extremities (hands and feet) or limbs, fatigue or asthenia (tiredness or weakness), mucosal inflammation (inflammation of the moist body surfaces), oedema (swelling) decreased ejection fraction (reduced amount of blood pumped out in each heartbeat) and decreased weight.