The most common side effects with Rapamune (seen in more than 1 patient in 10) are urinary tract infection (infection of the structures that carry urine), thrombocytopenia (low blood platelet counts), anaemia (low red blood cell counts), hypokalaemia (low blood potassium levels), hypophosphataemia (low blood phosphate levels), hypercholesterolaemia (high blood cholesterol levels), hyperglycaemia (high blood sugar levels), hypertriglyceridaemia (high blood levels of triglycerides, a type of fat), headache, lymphocele (fluid collection around the kidney), hypertension (high blood pressure), abdominal (tummy) pain, diarrhoea, constipation, nausea (feeling sick), acne (spots), arthralgia (joint pain), peripheral oedema (swelling, usually in the legs), pyrexia (fever), pain, increased blood lactate dehydrogenase levels (a marker of tissue breakdown) and increased blood creatinine levels (a marker of kidney problems).