3. Newly diagnosed or relapsed MPAL, which for this protocol, will be defined as follows: -Bone marrow result interpreted by the reading Pathologist (or tissue biopsy for cases of extramedullary disease) as: biphenotypic leukemia, bilineal leukemia, undifferentiated leukemia, mixed lineage leukemia, leukemia of ambiguous lineage, T/Myeloid leukemia, B/Myeloid leukemia, or other diagnosis indicating the presence of multiple lineages within the cell population.