After the consent forms are read and signed, participants will undergo a Structured Clinical Interview for DSM-IV (SCID) interview. In addition, symptoms will also be rated by rating scales that include the Clinical Global Impression (CGI), the Greene Climacteric Scale (GCS) and the Hamilton Depression Rating Scale (HAM-D (17-item)). To determine functional assessment in all participants, the Global Assessment Scale (GAF) will be used. All participants will also undergo an interview that will include a psychiatric and substance use history (including collection of data regarding the use of alcohol, tobacco, and illicit substances).