• Treatment of duodenal and gastric ulcer confirmed by endoscopy or radiography. • Treatment of reflux oesophagitis. • Long-term prophylaxis of reflux oesophagitis. • Zollinger-Ellison syndrome. • Treatment of NSAID-associated benign gastric and duodenal ulcers in patients requiring continuous NSAID-treatment • Prophylaxis of NSAID-associated gastric and duodenal ulcer in patients at risk requiring continuous NSAID-treatment