15. All patients must have adequate organ function as defined below. All screening lab tests should be done within 30 days before study registration. WBC >=2000/uL; Neuts >=1500/uL; PLT >=100x10^3/uL; HGB >9.0g/dL; Serum creatinine <=1.5xULN or creatinine clearance (calculated with the Cockcroft-Gault formula below) ≥40 mL/min: Men: ([l40-age in years] × weight in kg) / (72 × serum creatinine in mg/dL) Women: ([l40-age in years] × weight in kg) / (72 × serum creatinine in mg/dL) × 0.85; AST/ALT <=3xULN; Bili T <=1.5xULN (although patients with Gilbert syndrome can have total bilirubin <3.0 mg/dL)