The aim will be to compare the effects of a Pilates intervention program with a prescription of home exercises in individuals with chronic nonspecific low back pain. A second objective will be to assess the cost of interventions, associated with effects on outcomes. This is a randomized controlled clinical trial, characterized by the application of therapeutic exercises, in two modalities: Pilates Method and Home Prescription of Exercises. Participants will be sequentially enrolled and will be randomly allocated into two groups: 1) Pilates: which will be submitted to Mat Pilates sessions, 2x / week, for 6 weeks; 2) Home Exercise: 2 sessions of exercise supervised by a physiotherapist and, after, all participants will receive a booklet with the prescription of home therapeutic exercises, to be performed in the period of 6 weeks (2x/week) and monitored in a diary. Participants will be evaluated in three different moments: 1) Baseline (pre-intervention); 2) At the end of the intervention period (6 weeks); And 3) After two months of follow-up. Primary outcomes will be pain (measured by VAS), perception of recovery (likert scale of 6-points), functionality (measured by the Quebec Questionnaire - QDS) and kinesiophobia (measured by the Tampa Scale of Kinesiophobia). Secondary outcomes will be the postural balance and the quality of life. An economic evaluation will be carried out, from the economic perspective of the society, with a survey of direct and indirect costs, associated to the effects of the interventions. Data analysis will be performed through SPSS software version 22.0. The data normality assumptions will be evaluated using the Shapiro Wilk test. If the test confirms the assumptions, a mixed ANOVA with repeated measures will be used, based on the outcomes (functionality, pain, postural balance, quality of life, perception of recovery and kinesiophobia) and independent variables (Pilates and Home Exercises), for the comparisons between pre-intervention, post-intervention and follow-up. Pilates is expected to have better effects than the home exercise prescription group, associated with the outcomes of interest. In addition, the hypothesis is that the Pilates costs will exceed the costs from the home-based exercise prescriptions; however, the analysis of cost-benefit will demonstrate positive results in favor of the home-exercises.