Pre-operative planning is based on clinical and radiographic examination. After thoroughly recording the case history. The following investigations will be done prior to implant placement surgery: CBCT, CBP, CT, BT, Hg%, RBS, Vital signs and other relevant investigations. If all the parameters fulfill the inclusion and exclusion criteria, the patient's impressions are made and study models poured. Intraoral and extraoral photographs are taken. The surgical guide is constructed on the diagnostic models.Stem cells are carried from stem cell bank to the Department of Implantology in a cryovial, safely placed in the special device, which contains dry ice, to maintain the viability of stem cells.