Advocate is used for cats and dogs suffering from, or at risk from, mixed parasitic infections (caused by several different types of parasites): • for the treatment and prevention of flea infestations in cats and dogs • as part of treatment strategies for flea allergy dermatitis (an allergic reaction to flea bites) in cats and dogs • for the treatment of ear mite infestations in cats and dogs • for the treatment of biting lice infestations in dogs • for the treatment of skin diseases in dogs caused by parasitic mites (sarcoptic mange and demodicosis) • for the prevention of heartworm disease in cats and dogs • for the treatment of French heartworm disease in dogs • for the treatment of infections with certain (as specified in the Package Leaflet) gastrointestinal roundworms in cats and dogs.