Nelarabine has been administered in clinical trials up to a dose of 75 mg/ kg (approximately 2,250 mg/ m2) daily for 5 days to a paediatric patient, up to a dose of 60 mg/ kg (approximately 2,400 mg/ m2) daily for 5 days to 5 adult patients and up to 2,900 mg/ m2 in a further 2 adults on days 1, 3 and 5.