Uncommon side effects reported in at least 1 in 1,000 patients but less than 1 in 100 patients receiving Tygacil are: • Sepsis (severe infection in the body and blood stream)/ septic shock (serious medical condition which can lead to multiple organ failure and death as a result of sepsis) • Low protein levels in the blood • Acute pancreatitis (inflamed pancreas which may result in severe abdominal pain, nausea, and vomiting) • Jaundice • Injection site reaction (pain, redness, inflammation). • Inflammation of the liver