Common side effects Infections: pneumonia, herpes viral infection, upper respiratory infection, serious infection of the blood or tissues (including fatal outcome) Heart and lungs: palpitations, flushing, dizziness, congestive heart failure, cardiac dysfunction, high blood pressure Digestive problems: appetite disturbances, taste disturbance, bloated or distended tummy (abdomen), inflammation of the colon, constipation, heartburn, mouth ulceration, weight increase, weight decrease, gastritis Skin, hair, eye, general: skin tingling, itching, dry skin, acne, inflamation of the skin, persistant noise in ears, hair loss, excessive perspiration, visual disorder (including blurred vision and disturbed vision), dry eye, haematoma, depression, insomnia, contusion, anorexia, somnolence, generalised oedema Pain: pain in joints, muscle inflammation, muscular weakness, chest pain, pain around hands and feet, chills Tests may show: fluid around the heart, fluid in the lungs, arrhythmia, febrile neutropenia, deficiency in all blood cells, gastrointestinal bleeding