Alanine Aminotransferase (ALT) (or serum glutamopyruvate transferase SGPT) and a complete blood cell count, including a differential white blood cell count and a platelet count, must be checked simultaneously and with the same frequency: • before initiation of leflunomide • every two weeks during the first six months of treatment, and • every 8 weeks thereafter (see also section 4.4).