1. centralised applications for marketing authorisations for medicinal products (Council Regulation (EEC) No 2309/93, Article 4) 2. maintenance and pharmacovigilance activities (Council Regulation (EEC) No 2309/93, Articles 15-25, Articles 37-47) 3. establishment of maximum residue limits for substances in veterinary medicinal products (Council Regulation (EEC) No 2309/93, Article 51) 4. arbitrations and other Community referral procedures (Council Directive 75/319/EEC as amended, Articles 10, 11 & 12, and Council Directive 81/851/EEC as amended, Articles 18, 19 & 20) 5. scientific advice to future applicants and the EU institutions (Council Regulation (EEC) No 2309/93, Article 51) 6. information to health care professionals and public (Council Regulation (EEC) No 2309/93, Article 51) 7. technical support to international harmonisation initiatives (ICH, VICH, etc.) (Council Regulation (EEC) No 2309/93, Article 51) 8. support for the mutual recognition national authorisations, as requested 9. support for certain European policies at the request of the Commission or European Parliament 14 2.