Eligibility for enrollment will be open to women of all races and ethnicities who have completed a diagnostic XRM with a mammographically-detected lesion(s) in at least one mammographic view and have a lesion seen on HHUS corresponding to the XRM lesion(s). Women with a normal mammogram at the time of this evaluation are not eligible to participate. Women younger than 25 years of age will not be eligible to participate. Potential subjects must not be breastfeeding at the time of diagnostic breast imaging. Patients who have had breast cancer, breast surgeries, or interventional breast procedures in the past 12 months will not be eligible to enter the study.