- Weight >120kg -weight limit for dual energy x-ray absorptiometry (DXA) scan All subjects will undergo a full medical screening before being enrolled into the study. This screening will involve measures of height and weight, medical history and physical examination, blood tests (for fasting FBC's, U&E's, LFT's, TFT's, glucose, HbA1C, lipid profiles and coagulation), and ECG. Abnormal screening results will be discussed with the subject and their General Practitioner (GP) will be informed appropriately.