Randomization applied only to children who are new to our Center. When the results of growth factor and GH provocative testing are known, a two-step process will occur. Children, who are GHD, will be started on GH and entered into an on-going study already underway in our Center. They will not qualify for participation in the proposed NEW study. Children who have abnormal growth will be assigned to either the treatment or non-treatment category, using an adaptive randomization scheme to avoid imbalances in the numbers of subjects allocated to the two groups.