At each of the visits, all participants will be administered the CGI, HAM-D, and GCS questionnaires/surveys in addition to The Greene Climacteric Scale, which will be used to quantify symptoms of perimenopause. Also, participants will be asked at each visit if they have missed any doses during that particular week. Each of the office visits will last approximately 45 minutes. If necessary, telephone contact with investigators is permissible and will be available 24 hours/day for emergencies.