• With the other hand, hold syringe at 45-degree angle to skin, with the grooved side up. • With one quick, short motion, push needle all the way into skin • Release the skin with the first hand • Push plunger to inject solution – it can take from 2 to 5 seconds to empty the syringe • When the syringe is empty, remove the needle from skin, being careful to keep it at the same angle as when it was inserted • Hold the syringe in one hand and with the other hand slide the outer protective shield over the exposed needle until it locks in place • Using your thumb or a piece of gauze, apply pressure over the injection site for 10 seconds.