This is a phase IV, randomised, controlled, masked study recruiting patients with one treatment-naïve eye presenting with subfoveal choroidal neovascularisation (CNV) secondary to wet AMD. At screening, following the informed consent process, patients will be assessed for study eligibility by assessment of visual acuity using logarithm of the minimum angle of resolution (logMAR), stereoscopic biomicroscopic slit-lamp fundus examination (78 D or similar lens); fluorescein angiogram (FA); colour fundus photography; fundus autofluorescence and optical coherence tomography (OCT).