Patients will be randomized into either a test group receiving an ultrasound-guided TAP block with ropivacaine and peri-portal sterile saline or the control group that will receive ultrasound-guided TAP block with sterile saline and peri-portal infiltration of ropivicaine. All patients, who are scheduled to undergo laparoscopic cholecystectomy who meet the inclusion/exclusion criteria, and their parent(s)/guardian(s) will be called by the study staff the afternoon before surgery, who will follow a study script introducing the project and providing them with an opportunity to enroll in this study or opt out. If the patient cannot be reached the day before surgery, they will be offered the opportunity to enroll the day of surgery in the pre-operative holding area. If the decision is made to participate in the study, a physician study investigator will obtain appropriate consent and assent when applicable. Recruitment materials will be provided, if desired. A copy of this consent form will be placed in the Boston Children's Hospital medical record and a separate research record.