Number of seizure was the primary outcome variable, and was assessed by using a daily diary. For the baseline (pre-treatment) assessment, the caregivers were asked to record the number of seizures every day for 7 days during the baseline period on a daily diary. These 7 days numbers of seizures were averaged into a single rate per day of baseline average seizure frequency. During the 5 consecutive day of treatment, the caregivers were asked to record the daily children seizure frequency. Finally, daily 24-hour recording were administered for four weeks following treatment. 1-, 2-, 3-, and 4-week composite number of seizures were computed as an average of the daily number of seizures for each epoch (i.e., the 1-week follow-up average number of seizures = average of 7 daily number of seizures the first week after treatment).