With the increased preference for laparoscopic surgery, new instruments are needed to safely replicate and, where possible, improve upon the techniques used in open surgery. Visualization is eminently important and dependent on multiple factors, including bleeding and smoke from coagulation and cautery. Therefore, there is a high demand for devices that can safely coagulate tissue with low heat and little smoke. Resection of tissues in a safe and haemostatic fashion in laparoscopic colorectal surgery depends upon good control of mesenteric vessels. Ideally, the thermal spread should be minimal and travel in a predictable pattern. Various new devices have been created and used for the purposes of vessel sealing, with some of the more popular being Ligasure (Valleylab), Harmonic (Ethicon), Gyrus (Gyrus ACMI), and EnSeal (Ethicon). Multi-purpose instruments are preferable because the surgeon can avoid frequent exchange of instruments and thus reduce operative time. The previously mentioned vessel-sealing devices work with two jaws and can also be used to manipulate some tissue. Of particular interest to our group of colorectal surgeons is the finding that along with decreased operative time, these devices have been shown to contribute to decreased blood loss during laparoscopic colectomies.3 These modern vessel-sealing devices work by varying methods. The Harmonic Scalpel is an ultrasonic shear that breaks hydrogen bonds and cause tissue coagulation and vessel sealing.4 The Ligasure device works by coagulating the tissue in the jaws of the device with high-current/low-voltage flow and then using high-pressure jaws to seal it.5 The nano-particle technology of the EnSeal device aims to lower the temperature of the instrument to minimize heat transfer to adjacent tissue and allows for different temperatures within different parts of the jaws. It turns off when collagen denatures, at approximately 100 degrees Celsius.6 These sealing systems have been widely used in many surgical disciplines and surgeons continue to try to find new uses for these innovative devices. They have been compared to conventional methods such as clips and ties and found to be as effective when applied properly.7 The Gyrus PK system has been used in urological and robotic surgery.8, 9 The Harmonic Scalpel has been used in major abdominal operations and also in otolaryngology operations.10, 11 Ligasure has perhaps been the most widely adopted and is used in gynecological, otolaryngology, and colorectal specialties.12-15 The EnSeal device is newer than the others and while it is gaining popularity in its use, it has not been as extensively studied at this time.