(ii) We will be identifying and training the experts necessary for this study. We plan to recruit and train local medical personnel in clinical and laboratory practices. We want to develop necessary protocols for this study, put an infrastructure in place, and train medical personnel. This step is necessary not only for this study, but also for preparing for a vaccine trial (if possible). The goal is to lay the groundwork for all clinical studies to come, and to improve the conditions of vaccine research in Mali.