Patients with TS/CMT will be candidates for this study if: 1) they are tic-suppressing drug naive; 2) are not currently on treatment for TS (off medications for at least three weeks); or 3) if, in the judgment of the Investigators (Dr Singer and Grados), they are not adequately managed using current therapy (prescribed for greater than one month) and are willing to maintain a constant dose throughout the protocol. We believe that limiting the study to include only "drug-free" subjects would have a negative impact on recruitment. Many individuals with moderately severe to severe tics (TTS > 22) are receiving medications and in our opinion requiring prolonged tapers and extended drug free intervals are not in the best interest of the patient.