ICU survival Hospital survival Severity of organ dysfunction in the ICU (SOFA score 5) Duration of ICU stay, time spent on vasopressors (vasopressor free days), on mechanical ventilation (ventilator free days) and on renal replacement (renal replacement free days) Efficacy of dopamine to correct hypotension Hemodynamic effects / concomitant use of dobutamine or other inotropic agents Tolerance: arrhythmia (incidence of ventricular tachycardia, ventricular fibrillation and atrial fibrillation), myocardial necrosis, skin necrosis, limb or distal extremity ischemia.