The human intestinal tract is known to be colonized by hundreds of different bacterial species and other microbes. Based on the experience with fecal microbiota therapy in the treatment of recurrent Clostridium difficile infections, it can be hypothesized that the intestinal microbiome may influence the success or failure of the present study intervention. Thus, at selected sites, a metagenomic analysis of the intestinal microbiome will be performed to explore possible associations between certain microbiome patterns and the successful eradication of ESBL-E.