Immunohistochemistry: Monoclonal antibodies will be used for immunostaining of VDR, CaSR, PTH, Cyclin D1, Ki67 and PCNA proteins on paraffin sections (Source- Pharmingen, USA). Secondary antibody, goat anti-mouse horse radish peroxidase conjugated (BD Biosciences, Pharmingen, USA), specific for primary antibodies will be used in each test. Indirect immunoperoxidase method will be used for the staining of paraffin sections. In this assay, the unconjugated primary antibody binds to the antigen in the specimen. To localize this attachment, a peroxidase conjugated specific secondary antibody is used which binds to the primary antibody. A substrate is than added to localize the reaction.