Intervention One group will be given antioxidant supplementation and the other group will be placebo. The antioxidant intervention will be daily doses of 600 mg organic selenium, 0.54 g vitamin C, 9000 IU B-carotene, 270 IU vitamin E and 2 g methionine. Both the groups will be supplemented with the pancreatic enzymes. The enzyme will be administered as capsules, each containing 10,000 units. Three capsules (30,000) units will be required per meal thereby making it to 90,000 units per day.