- BPR measurements were performed using the Cold Pressor Test (CPT) according to specifications previously described by Hines & Brow3. These authors had demonstrated the high reproducibility of the procedure for both normotensive and hypertensive individuals. The protocol consisted of one minute immersion of the right hand in water carefully kept at 4º C (Incoterm®, Porto Alegre, RS). BP measurements were respectively taken 30 and 60 seconds of immersion through the auscultatory method. The two BP values were respectively named Peak30" and Peak60" and the procedure is considered as an index of BPR. BP was also measured two minutes after the immersion cessation (After2'). Of note, the adoption of the auscultatory method for BP evaluation was due to the requirement of measurements at 30 and 60 seconds, what would not be possible using the automated oscillometric device.