a.Potential subjects will be recruited by public advertisement in the School of Dentistry clinics, including MCOHR, and the Chronic Pain and Fatigue Research Center in addition to other University of Michigan clinics. They will also be recruited via UMClinicalStudies.org, the DaSilva lab webpage (with a flyer for the study listed under current research), ClinicalTrials.gov, and the U.S. National Institutes of Health. In addition, subjects may be recruited by the PI or study staff in a private setting. The potential subject's healthcare providers will be able to suggest the availability of the study and inform them of a place where they will be able to find more information about participating in the study.