This phase will take 22 months. In the selected municipalities, the health personnel that work in hospitals and health centers will receive training regarding the disease and the study methodology. Simultaneously an epidemiological focus study will be done with the leaders of the community and the health personnel to identify the geographic and demographic conditions with the purpose of developing strategies for the recruitment of possible cases of leishmaniasis. Subsequently, the subjects that present active ulcers with more than 2 weeks of evolution, with or without parasitological confirmation of CL, will be invited by the health promoters to attend the screening visit (Table 1).