ADVERSE EVENT REPORT PROCESS Adverse events supervision committee The Clinical Events Committee (CEC) is composed of interventional experts who have no relationship with Medtronic and all study centers, and they will not directly attend the current study. CEC will supervise and determine the events according to the current guidelines as well as the regulations that immobilized to the current study. CEC will also do the inspection and determination according to the study endpoints that are based on the systemic analysis of the raw data collection, electrocardiogram, angiography and so on to ensure a central, systemic, standardized, independent and impartial evaluate process.