All patients will undergo detailed clinical evaluation including detailed family history of pancreatic diseases and diabetes. The WHO criteria will be used to diagnose diabetes. The patients will also be inquired about their dietary history and addiction to tobacco or alcohol. Patients will be explained the purpose of study clearly and consent forms will be duly signed by them. The patients will be regularly followed up in pancreas clinic at All India Institute of Medical Sciences, New Delhi. All the patients will be treated in the standard manner including medical, endoscopic and surgical treatment as and when indicated.