UC-MSC will be prepared according to standard procedures and is collected in plastic bags containing anti coagulant. MSCs are given via i.v. under sonography monitoring. After cell therapy, patients are followed up at week 4, 8, 12, 24, 36 and 48. The evaluation of some clinical parameters such as the level of ascites volume and ascites disappearance rate, serum alanine aminotransferase (ALT), total bilirubin (TB),prothrombin time (PT), albumin (ALB), prealbumin(PA), the rountin blood test, renal function test are detected at these timepoints. MELD-Na scores and clinical symptoms as well as complication were also observed simultaneously.