Study Procedures At study visits, clinical data are collected and laboratory analyses comprising CD4+ T cell count, plasma HIV-1 RNA, blood cells, and plasma chemistry profiles, including fasting lipids (total cholesterol, high-density lipoprotein cholesterol [HDL], low- density lipoprotein [LDL] cholesterol, triglycerides) are recorded. Plasma HIV-1 RNA and all other laboratory determinations are performed locally at each site throughout the follow-up period.