All infants assigned to the center-based care group were seen in the regional, high-risk infant multidisciplinary clinic at Wake Forest University School of Medicine. The first clinic visit occurred approximately one month after their discharge. A multidisciplinary team consisting of the social worker, the nurse specialist and the neonatologist obtained detailed interim medical history (feeding, respiratory status, medication history, illnesses and health-services utilization) and performed a complete physical examination. Family stressors and resources were discussed. All infants were scheduled for visits at four, eight, and twelve months adjusted age. In addition, infants who were using supplemental oxygen were seen at an interval of 1-2 months until all of the following criteria were met: 1) their growth rate was 15-30 grams/day, 2) they were no longer using supplemental oxygen or other medications, and 3) they were no longer using a home apnea monitor. At each clinic visit, the infant and parent or guardian were seen individually by the clinic social worker, the nurse specialist for this project, and one of the two neonatologists who conferred as a group and developed a plan of care. This plan was communicated to the family by the nurse specialist.