Following an overnight fast of at least 10 hour, a single oral dose of valacyclovir hydrochloride 1 gram of either test or reference investigational product was administered during each period of the study, along with 240 mL of drinking water at ambient temperature under low light condition and under supervision of trained study personnel. Both test and reference products were administered to all the study subjects, one in each period (except subject numbers 04, 21 and 27 who dropped out from the study).