Currently, the EnSeal is approved for vessels as large as 7 mm in diameter. We believe, based on prior clinical experience, that the EnSeal can safely seal vessels of a larger diameter. Current data shows that the bursting pressures obtained in 7 mm vessels are five times the physiological normal pressure in animal models.1, 2 We have demonstrated that all of the mesenteric vessels encountered in a human colectomy can be safely divided with EnSeal. However, neither we nor other researchers have measured the bursting pressure of these seals in human patients.