However, the role of oxidative stress still not fully explained in that whether the oxidative stress is the cause of chronic pancreatitis or a consequence of it. This can be established by two observations: 1) If the oxidative stress is noted before the onset of disease and 2) If the disease symptoms are relieved by supplementation with antioxidants. Patients with alcoholic pancreatitis have been shown to have an increased oxidative stress. Supplementation with antioxidants hence decreases the production of such free radicals and may be beneficial to patients with CP (4).