RESEARCH PLAN/METHODOLOGY: Electronic Patient Reported Outcomes (ePRO) is a web-based software tool developed by the Women & Children's Health Research Institute (WCHRI) at the University of Alberta. Pilot studies have been performed at the University of Alberta, however, this study will be the first use of ePRO in a study population of this size. Questionnaires are built using Checkbox Survey Server. Automatic email invitations to participants are based on the individualized anchor dates and schedules (e.g., the questionnaire for children aged 12 months is linked to the individual child's date of birth). Participants receive links and instructions when a survey is due for completion. Reminders are automatically sent if a questionnaire is not completed within appropriate timelines (e.g., after 2 weeks). Study staff can track late and incomplete questionnaires, re-send invitations, and manually enter data when information is obtained via a paper questionnaire or telephone interview. Importantly, the system facilitates linking of data from different questionnaires and different time points.