- All patients are sedated with an initial dose of 100 milligrams (mg) propofol. In addition 20-50 mg propofol is administered when patient discomfort or lighter levels of sedation are noticed. The nurse qualified in sedation management determines the doses of propofol on a previously described sedation protocol for the CASA clinics. Local anesthesia of the cervix is performed with 10-20 ml lidocaine 1%.