Because of the lack of standard methodology of studies of candidate genes relevant in the rare disease, we will take genetic research, using these samples to identify the genetic basis of KS using array CGH high density (44000 clones) on an AGILENT platform (Dr. D SANLAVILLE, Lyon). This research, already used successfully in other sporadic dominant rare diseases (such as CHARGE syndrome), we may help to identify an anomaly INFRACYTOGENETIQUE to locate the gene responsible for SK.