Step 1: Enrollment into this study period was similar to the procedures in Period 1. Participants were consented to protocol v6.0, completed screening and after meeting eligibility, enrolled on the study at Visit 2. The leukapheresis, scheduled for Visit 2, was optional based on prior ascertainment of baseline parameters. Omission of this leukapheresis was determined by study PI, after analysis of lab data from previous leukapheresis procedures. Regardless of the completion of the leukapheresis procedure at Visit 2, study enrollment and collection of required research assays was completed at Visit 2. Participant were screened and enrolled into Step 1 until 12 evaluable participants successfully completed the multiple doses of VOR (Step 4), or until the study-stopping rules are met. It is estimated that up to 30 eligible participants may be screened and enrolled to provide a total of 12 evaluable participants who complete Step 3.