Lactose intolerance: Bovine colostrum extract generally contains <10% lactose, compared with about 50% in normal skim milk powder; therefore, lactose intolerance is unlikely to be a major safety problem. Clinical signs can be expected in susceptible humans given 5-10g of lactose (Thorn et al, 1977). At a dose of bovine colostrum extract of 10g a day (2.8g more than the dose proposed in this study), a maximum of 1 g would be lactose.