Specific strategies to achieve the medication adherence goals. Participants list all of the medications they take and keep this list in a notebook. The purpose of each medication is explained to the participant as well as the reasons for always taking the medication each day as prescribed. Participants are encouraged to develop the habit of taking their medications as prescribed at the same time each day. Discussions about handling weekends, going on vacation, etc. are discussed during intervention sessions. Reminders about taking medications are offered at each session and each phone call. Refills of medications are carefully tracked. When participants report that they are running low on a medication they are encouraged to obtain refills promptly. Reported side effects of medications are carefully monitored and attempts made to determine if the side effects are easily remedied (e.g., take just before bedtime, take with breakfast) or are due to not following instructions correctly. If necessary the participant is referred to his or her physician for consideration of a change in medication.