a. Hematology: hematocrit, hemoglobin, white blood cell count with differential, platelet count b. Serum chemistry: glucose, creatinine, blood urea nitrogen, aspartate transaminases (AST), alanine transaminase (ALT), alkaline phosphatase, total and direct bilirubin, sodium, potassium, chloride, calcium, magnesium, total protein, albumin f. Record results of sterile body fluid cultures (blood, urine, CSF, peritoneal fluid) obtained as standard clinical care in the 72 hours prior to study drug administration. Record urine cultures only if obtained by sterile catheterization or suprapubic aspiration g. Document antimicrobials and vasopressors in the 72 hours prior to study drug administration