4. Inclusion criteria: age 30-80 years old ( might differ based on certain cancer type) ; newly diagnosis of solid tumor proved by imaging; pathology proved to be primary solid tumor; first PET/CT scan was performed before any kinds of anti-tumor treatment including surgery; no other anti-tumor treatments except for that required during the trial; written and informed consent with signature before the study; complete medical history and clinical record (including physical examination, electrocardiogram, hematology, biochemistry, tumor pathology etc); follow-up of PSF and OS over a year