Following an overnight fast of at least 10 hour, a high-fat high-calorie breakfast was served to the study subjects. Thirty minutes after start of this breakfast, a single oral dose of Valacyclovir hydrochloride 1 gram of either test or reference investigational product was administered during each period of the study (on day 01 and 04), along with 240 mL of drinking water at ambient temperature under low light condition and under supervision of trained study personnel. Both test and reference products were administered to all the study subjects, one in each period (except subject number 14 who dropped out from the study and subject number 37 who was withdrawn from the study).