Significance of the Project Diabetes along with obesity is one of the leading non-communicable diseases in the developed and developing countries. More than 29 million Americans are diabetic and another 86 million are in a pre-diabetic state. The cost of diabetes in 2012 was $245 billion and it is growing. Hypohydration on the other side, is a quite common phenomenon linked to many health issues like urinary tract infections, kidney stones, cardiovascular diseases, mood state and cognitive performance. One of the potential mechanisms behind the effects of hypohydration is the elevated level of AVP. Recent epidemiological data and experiments in animals indicate that hypohydration and high vasopressin are linked to both diabetes and glucose dysregulation. However, no experimental data from a controlled trial in humans exist. The purpose of the proposed study is to perform a controlled trial on healthy humans to examine the effect of elevated vasopressin on glucose regulation.