Part 1, a dose escalation phase, in which the Maximum Tolerated Dose (MTD) and Development Regimen will be determined in up to 42 patients with advanced or metastatic solid tumors. Treatment will be administered in 28-day cycles, with the exception of the first cycle, which will have a lead-in of 7 days dosing of CORT125134. CORT125134 is administered orally (PO) once daily for 28 days. Nab-paclitaxel will be administered intravenously (IV) on days 1, 8 and 15.