The primary outcomes of the study will be: a) depression; (b) weight and waist circumference; (c) HbA1c; and (d) medication adherence. Secondary outcomes will include: (a) glucose tolerance, (b) insulin resistance, (c) inflammation, (d) fibrinolysis, (e) lipid profile, (f) oxidative stress, (g) endothelial function, (h) resting blood pressure, (i) cardiac and vascular function, (j) cardiac morphology, (k) psychosocial functioning, and (l) health quality of life. The above variables will be assessed at baseline, after 6 months and after 1 year. Data will be analyzed using mixed-model analyses to determine change over time as a function of experimental condition. This will be done using the PROC Mixed module of SAS software (Littell, Milliken, Stroup, & Wolfinger, 1996). This methodology is useful for intent to treat analyses in that it does not require complete data across multiple time points.