The use of radiation in the treatment of non-oncologic human populations has enjoyed a long history and a more recent renaissance. It is now commonly used to prevent heterotopic bone formation and re-development of keloids or heterotrophic scars post-operatively. It has been shown in a randomized trial to effectively treat planter fasciitis and has been used in post-operative treatment of resected pterygium. It has been used in the treatment of Hidradenitis suppurativa, Duputryen's disease and Ledderhose's disease. These sites routinely are treated with low dose fractionated external beam irradiation, commonly in doses that ranging from 7 to 24 Gy.