Moxifloxacin is well-suited to study drug-induced QT prolongation, as it is known to cause transient and mild QT prolongation. Compared to placebo, 400mg of oral moxifloxacin is associated with an approximately 10 msec increase in the heart rate-corrected QT interval14, 15. Despite this increase in QT interval, there is no reported increased risk of sudden death with oral administration of a single dose of moxifloxacin16, so it is a safe and well-validated drug to use in the study of cardiotoxic drug response in healthy human subjects. Moreover, it has been widely used by the pharmaceutical industry as a positive control as required by the FDA to demonstrate a sufficiently sensitive method to detect QT prolongation.