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Children with Cancer Have Complete Responses in a Children's Oncology Group Phase 1 Trial
--Children's Hospital of Philadelphia Researcher Leads Trial of
ALK Inhibitor in Neuroblastoma, Lymphoma--
PHILADELPHIA, May 16, 2012 /PRNewswire/ -- A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
To view the multimedia assets associated with this release, please visit: http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
(Photo: http://photos.prnewswire.com/prnh/20120516/MM07672 )
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children's Oncology Group (COG). The results were "an exciting proof-of-principle" for the targeted treatment, said the study leader, Yael P. Mosse, M.D., a pediatric oncologist at The Children's Hospital of Philadelphia.
Mosse presented study findings today at a press program organized by the American Society of Clinical Oncology (ASCO) in advance of its annual meeting in early June. In addition, the society selected the research for its Best of ASCO program following the meeting, and has announced that Mosse will be the first recipient of its James B. Nachman ASCO Junior Faculty Award in Pediatric Oncology.
Mosse previously led a team at Children's Hospital that discovered in 2008 that aberrations in the anaplastic lymphoma kinase (ALK) gene are present in 14 percent of cases of high-risk neuroblastoma, the most common solid cancer of early childhood. The same gene is disrupted in some cases of anaplastic large cell lymphoma (ALCL), a cancer of the lymph cells, and in patients with non-small cell lung cancer. Because drug manufacturers had already developed crizotinib for use in adult lung cancer clinical trials, Mosse and colleagues were able to quickly move crizotinib into an initial pediatric trial.
"We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue," said Mosse. "In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care."
The current trial was not restricted to patients with known ALK abnormalities, but was open to children with certain refractory or relapsed cancers. There were 62 patients enrolled who could be fully evaluated for drug toxicity. Toxic side effects were minimal, even though many of the dosages were relatively high.
For 8 children with ALCL, 7 had complete responses — no cancer could be detected with imaging scans. Within days of taking the oral medication, said Mosse, fevers and chills stopped in many children, and their pain diminished or disappeared.
Twenty-seven patients enrolled in the trial had neuroblastoma, a difficult-to-treat cancer of the nervous system. Of the two patients with known germline mutations in ALK—mutations occurring in every cell in their body, which can be found in the very rare form of neuroblastoma, familial neuroblastoma, one achieved a complete remission. Of the 19 neuroblastoma patients in the trial whose ALK status was not able to be studied in the molecular diagnostic lab at Children's Hospital, a second patient had a complete remission.
"The current study shows the great potential for targeted therapy in children with anaplastic large cell lymphoma," concluded Mosse, "and the COG is now planning a larger scale trial for these patients." Additional studies are also underway to determine whether children with forms of neuroblastoma other than familial neuroblastoma, as laboratory studies suggest, might benefit from crizotinib.
Financial support for this Children's Oncology Group study came from the National Cancer Institute and from Pfizer, Inc. Co-authors with Mosse included researchers from The Children's Hospital of Philadelphia, C.S. Mott Children's Hospital, Children's Hospital Boston, the University of Minnesota, Minneapolis, Baylor College of Medicine, and Texas Children's Cancer Center.
"Efficacy of crizotinib in children with relapsed/refractory ALK-driven tumors including anaplastic large cell lymphoma and neuroblastoma: A Children's Oncology Group phase 1 consortium study," Abstract 9500, American Society of Clinical Oncology, 2012 Annual Meeting.
Ab out The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking third in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 516-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit http://www.chop.edu.
About the Children's Oncology Group: The Children's Oncology Group (childrensoncologygroup.org) unites more than 7,500 experts in childhood cancer at more than 200 leading children's hospitals, universities, and cancer centers across North America, Australia, New Zealand, and Europe in the fight against childhood cancer. The COG research has turned children's cancer from a virtually incurable disease 50 years ago to one with a combined 5-year survival rate of 80% today. Our goal is to cure all children and adolescents with cancer, reduce the short and long-term complications of cancer treatments, and determine the causes and find ways to prevent childhood cancer.
Media Contact:
Rachel Salis-Silverman
The Children's Hospital of Philadelphia
Office: (267) 426-6063
Cell: (267) 970-3685
SOURCE The Children's Hospital of Philadelphia
Web Site: http://www.chop.edu
Posted: May 2012


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Toyota, With Loss, Still Not As Bad As GM
By manufacturing cars in the United States, Toyota has run into a currency risk—currency fluctuations. When dollars are repatriated to Japan, the dollars must be converted to yen. It has been estimated that Toyota loses $400 million for every 1 yen that the Japanese currency increases in value.
[On The Car Industry]
Toyota recently announced a loss in 2008 for its automobile operations of 150 billion yen ($1.7 billion) versus a profit in 2007 for its automobile operations of 2.3 trillion yen ($18.9 billion).
A decline in demand; a reluctance of banks in the United States to provide financing for automobiles; and, wariness by consumers to purchase new cars are the reasons. Toyota is the most profitable automobile manufacturer in the world.
But why the loss? A little history is needed.
In the late 1970's Detroit's big three, General Motors, Ford and Chrysler, currently known collectively as The Three Stooges, were being decimated by imported Japanese car manufacturers, Toyota and Honda. The reason: The quality of American cars was equivalent to the quality of our education system—horrible.
In 1980 Chrysler was so desperate for money that the American government financed Chrysler with a $1.5 billion loan. The United States government initiated tariffs of approximately $1,000 on every car that was imported from Japan. Americans eagerly purchased small fuel-efficient Japanese cars anyway.
Lee Iacocca was angry. After all it was Iaccocca, who while at Ford, conned the American public into purchasing the Ford Mustang, a car powered by a Falcon engine with horrible suspension.
Iacocca dared Toyota and Honda to manufacture cars in the United States. Iacocca believed that Honda and Toyota would produce cars in America that had defects like American cars and that the United Auto Workers Union (UAWU) would unionize the Japanese work force as well. He was confident that the Japanese auto companies would be knocked out of the competition.
Honda and then Toyota established auto manufacturing plants, at first mainly assembly plants with parts imported from Japan, in the United States. Later Honda and Toyota built manufacturing plants. Toyota and Honda did not build their plants in the industrial heartland. Toyota and Honda built plants in states such as Tennessee and Alabama. The automobile plants were not unionized.
By manufacturing cars in the United States, Toyota has run into a currency risk—currency fluctuations. When dollars are repatriated to Japan, the dollars must be converted to yen. It has been estimated that Toyota loses $400 million for every 1 yen that the Japanese currency increases in value.
Earlier this year the yen was quoted at 110 to the dollar. Currently the yen has strengthened to 90 yen—a stronger yen purchases fewer dollars. One reason for this increase in the value of the yen is that there are low interest rates in both the United States and Japan. If interest rates were higher in the United States than in Japan, the yen would be worth less.
Thus a decrease of 20 yen to the dollar leads to a loss due to currency exchange rates of $8 billion. Ironically, it is actually the strengthening yen that has provided a loss for Toyota.
Still GM, Ford and Chrysler could not compete and have lost billions of dollars in 2008, and have effectively run out of cash. So, GM and Chrysler have borrowed $17.4 billion from the United States Treasury.
Toyota does not need to borrow money. Toyota has cash reserves exceeding $18 billion -- and an excellent credit rating.
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Show Celebrates Huge 50-Year Milestone
Actor Anthony Geary discusses "General Hospital's" historic anniversary in Times Square.
Want to Be a Soap Star? 'General Hospital' Casting Director, Mark Teschner, on What He Looks For
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Taming the monster VoIP survey
Business communications revisited
Reg reader studies Every now and again, we don't nail things first time when it comes to questionnaire design, so first, apologies to all those who took one look at our monster Unified Communications survey last week and decided, understandably in hindsight, it wasn't for them.
The problem we had was wading into the specialist stuff right away, meaning non-specialists were confronted with a load of questions they couldn't answer comfortably. we fell into the trap of assuming there was a lot more knowledge of unified comms out there than there actually is. Taking on board your feedback (and, quite frankly, noting the high bail out rate), we have therefore given the survey a makeover.
So, take a look at new version if you have things you want to tell us about the evolution of business communications in general. We have restructured the survey into sections, starting out with generic questions on things like telephony, messaging, conferencing, etc, then moving onto unified comms, firstly at a high level, then drilling into some of the implementation specifics for all you experts out there. The idea is that you can comfortably answer as much or as little as you want.
The new survey is available here:
In the meantime, a big thanks to those who completed the original version last week – for those with experience, it seemed to work very well. Anyway, no need to go there again as the core questions haven't changed, they have just been reorganised to make the survey more accessible to non-specialists.
Sponsored: Minds Mastering Machines - Call for papers now open


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I recently started wiping my film cassettes with an Ilford antistaticum before loading film. A lot of LFP books recommend using a brush to clear out the cassettes but an old grayback LFP suggested this will actually charge the cassettes and he suggested I should use the Antistaticum.
I haven't been doing it long enough to see if my dust problem has diminished. Anybody else does this?


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Microwaved Barbecued Pork Chops Recipe
3.5 4 3
A homemade barbecue sauce tops these moist, tender chops from David Bray of Hoover, Alabama. "We like to use the microwave and love this recipe because it's so quick and easy to prepare."
Recommended: 55 Labor Day Grilling Recipes
VERIFIED BY Taste of Home Test Kitchen
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- 6 boneless pork loin chops (4 ounces each and 1/2-inch thick)
- 1 medium onion, chopped
- 1 cup ketchup
- 1/2 cup water
- 1/2 cup chopped celery
- 2 tablespoons lemon juice
- 1 tablespoon brown sugar
- 1 tablespoon Worcestershire sauce
- 1/2 teaspoon salt
- 1/2 teaspoon ground mustard
- 1 teaspoon cornstarch
- 1 tablespoon cold water
- Place pork chops in an ungreased 11x7-in. microwave-safe dish.
- In a large bowl, combine the next nine ingredients. Pour over the chops. Cover with plastic wrap; peel back one corner to vent. Microwave on high for 11-13 minutes or until juices run clear. Remove chops; set aside and keep warm.
- In a small bowl, combine cornstarch and cold water until smooth. Stir into barbecue sauce. Microwave for 30-45 seconds or until thickened. Serve sauce over chops. Yield: 6 servings.
Editor's Note: This recipe was tested in a 1,100-watt microwave.
Originally published as Barbecued Pork Chops in Quick Cooking January/February 2000, p51
Reviews forMicrowaved Barbecued Pork Chops
My Review
Click stars to rate
Any changes to your rating or review will appear where you originally posted your review
Average Rating
Reviewed Nov. 6, 2012
"My Mom used to make this when I was a kid. She always used bottled Kraft BBQ sauce. She recently passed & I am excited to find the "recipe", as she never told me how long to cook the pork. Can't wait to surprise my Dad with this favorite!"
Reviewed Jan. 24, 2012
"This seems like a recipe someone made up. It's edible, but I won't do it again on purpose."
Reviewed Oct. 29, 2011
"I made the recipe as written. It was fast and very good."
Reviewed Jun. 1, 2010
"was in a hurry and I used a store brand barbecue sauce and it turned out great. Will make again with the barbecue sauce that is in the recipe."


text:
Best Buy says third-quarter earnings rose 21 percent, but hinted that holiday season profits may fall short of what analysts are predicting.
The nation's largest electronics retailer predicted fourth-quarter earnings at the low end of analyst estimates, partly because more discounts are being offered.
Best Buy predicted fourth-quarter earnings of $1.56 to $1.66 a share.
That would be 13 percent higher than last year.
Analysts are expecting $1.62 per share.
For the three months ending on November 27, Best buy earned $148 million, or 45 cents per share. Best Buy operates stores in Eau Claire and La Crosse, and is headquartered in the Twin Cities.
That number is up from $122 million, or 37 cents per share in last year's third quarter.


text:
TROY -- A Troy teen accused of murdering her father over the use of a credit card was denied bail.
On Wednesday morning, Rensselaer County Court Judge Andrew Ceresia listened to a bail application from an attorney representing Trinity Copeland, 17, the Troy High School student being held for allegedly shooting her father, Harlan Copeland, after a dispute over the use of one of his credit cards.
Despite pleas from defense attorney Matthew Smalls, Ceresia denied bail in the case and ordered Copeland back to jail.
The case stems from the July 2012 shooting death of the elder Copeland in his home. Troy police responded to a 911 call from Trinity Copeland herself, arriving at the Copeland residence to find the elder Copeland lying dead on the couch with a single gunshot wound to the head.
The teen allegedly confessed to the shooting, stating she did it on the orders of her father, who threatened to kill her if she didn't shoot him.
Copeland faces the possibility of life imprisonment after a grand jury returned an indictment against her charging second-degree murder. She is currently being held at Rensselaer County Jail.
Charles Sweeney may also be reached at 270-1252


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Member # 49145
Hi there,
I am a female (biologically speaking) and am okay with being seen as a female/girl most the time (so long as I don't feel I'm being labelled as a female to my disadvantage!). I have always struggled with the term "woman", mainly because of what I feel it represents in society at large (basically being seen as the lesser gender in society, secondary to men).
From a young age I've learnt to identify more with my dad (someone who I see as having strength/power). I would describe myself to be more genderqueer in this sense as I sort of feel inbetween genders here (i.e. identifying with my dad takes me out of the "woman" role).
It's strange really, my attitude towards masculinity is really ambivalent. On the one hand, I am against masculinity taking over and being the dominant force in society, yet at the same time, I envy it too!
Anyway, basically I've recently become involved with a boy/man (aged 24), somoeone who although is soft/gentle (particularly in comparison to other "men"), also really aspires to be a "man" in the societal sense, which basically leaves me feeling REALLY uncomfortable and awkward because I feel like I'm lesser (I've basically developed this huge inferioty complex to men!).
I feel really torn because I really like him... just not what he stands for and what he aspires to be (and how this makes me feel in contrast). I have spoken to him about this and he's incredibly understanding, but I still feel distinctively "female" around him... (which is ok for the most part) but it's never too long before I start to feel secondary to him being the "man" again. I literally feel my behaviour changing around him to be more submissive!
Note as well, I love his sensitivity and have tried to tell him that I'd love it if he were to express this side of him more (therefore allowing me to play that "male" part). He agrees but says he doesn't want to be labelled as gay or a pansy, either! (something I couldn't disagree more with!).
Of course I'm also aware we shouldn't change people though... I'm so torn on how I feel about this.
Any advice would be greatly appreciated as this is really starting to get me down and I don't want to hurt him either
Member # 69019
It seems like you need to stop putting so much emphasis on gender. How someone acts or wants to come across as shouldn't be so heavily influenced by it.
Member # 3
I think it's fair to say that just like other ways we can feel we fit or don't fit with people, we're going to feel like our gender identity is a better fit with some people than others.
In other words, we may feel, in one relationship, that how who we are per gender feels like a good fit, feels like we can feel good about it and be who we are, while in another, it might feel like what our gender identity is is challenged or not at home.
So, I think maybe the first question is this: with where you're at with gender, do you feel comfortable dating/being intimate with men? Is that something you want and something that feels like a fit for you right now?
Member # 3
(Hey blush, just a quickie: how important gender is or isn't to people is very individual and personal, so we'd like for everyone here to try not to put "shoulds" on people around this. Thanks!)
Member # 49145
Hi Heather,
Thanks for the quick response. I'm not sure, as I say I really like who he is... deep down if that makes sense? but I also feel like the way in which he identifies and the values he has are maybe not such a good match for me. I think I maybe need someone who is willing to be more flexible when it comes to gender, act a bit more feminine and not feel that they can't do that for fear of not being a "real" man. This is obviously something I need to talk about with him, but yeah I definitely feel an uneasiness with him (which is a shame because he's not doing this intentionally)
On a related note, I also really fear I'm never going to find a man who is ok with acting more feminine... (basically not being a man!) even the most sensitive men (like the person I've become recently involved with) still seem too male for me...
Member # 3
So, am I understanding that you do want to date/feel attracted to men/people who identify as men exclusively?
In other words, at the risk of sounding obvious, when you say you worry you won't find someone who basically isn't a man and who is feminine, is there a reason you're not looking to date people who aren't, who are/identify as women?
[ 07-13-2011, 09:58 AM: Message edited by: Heather ]
Member # 49145
I definitely want to date a male... I know I'm not attracted to females (sexually, at least).
However, I really do feel threatened by masculinity, as in I feel it threatens my sense of self, if that makes sense?
I love the idea of a feminine male (someone who is biologically male but has a very feminine side to them). I guess I do have certain reservations about how far this femininty would go... and that's sad, but defintiely the effects of society/conformity etc. I love the idea of masks, the idea that someone can *look* masculine and play the part (when needed) but who is actually really feminine on the inside, like when we're alone together and willing to explore different areas outside the mainstream... I need to feel this freedom to express myself and for him to express himself.
Just not sure how to find these men though... but yeah I guess I love this quirkiness and someone confident enough to pull it off.
Member # 3
So, am I getting right that what you're attracted to and also most comfortable with is androgyny or people who are genderqueer?
Member # 49145
Hmmm, yeah I guess that is it... in character at least. I don't think it's attractive for a man to dress up as a woman though... for me at least, I think that takes it too far.
It's a shame because my last/first boyfriend was basically like how I'm describing. He had a very feminine character although we never explored gender in any real depth (mainly because we were too young I think). But I definitely felt like the "man" in that relationship. Unfortunately too, I felt like the only one in the relationship because he was so passive... it's a tricky one.
Member # 3
To make sure I'm clear, someone who was assigned male sex, but who identifies as a woman or as genderqueer and wears clothing they feel is reflective of them which someone identifies as "women's clothing," isn't "dressing up as a woman." They're dressing as themselves. Do you understand what I'm saying?
In other words, yes, for some men, wearing "women's" clothing (I put that in quotes because the idea that clothing has gender is problematic to begin with) is crossdressing. For others it is not. It's no different than you wearing whatever clothes you feel express your gender.
Member # 49145
Yeah I completely understand what you're saying. Like I don't see my clothes as "female" at all... they're just mine. but I know society does so that kind of influences my thoughts about what I wear sometimes (ie. if I wear highly feminine clothes/heels/beads etc I then feel very... female!). lol, I know it sounds silly but I do. I dunno, I guess I just assumed that a man dressing up as a woman would do so because it made him feel a particular way as well... ie. more of a woman? and I'm not entirely sure how much I want a "woman" lol.
Eurgh, I don't know... I feel like I'm asking for the impossible... a man who is a man but isn't too much of a man and who isn't too feminine either! argh lol
Member # 3
Again, I think it's tricky to even say "man dressing up as a woman" with that kind of certainty. You say you don't see your clothes as being women's clothes, so why see what a man is wearing as having gender if that person doesn't feel that clothing does?
I'm not sure you're asking for the impossible, I just think that there are some ways you're framing gender that a) aren't in alignment with how you see it for yourself (in other words, I think you may be employing some double standards) and b) than you may be stuck in a way of seeing gender as binary -- as only about man or women, masculine or feminine -- that could be getting in the way of recognizing what it is you want, both for yourself in your own identity, and in a partner.
Know what I mean?
I mean, what I hear when you say "a man who is a man but isn't too much of a man and who isn't too feminine either," what I hear is "someone whose gender identity is not very binary, or who is genderqueer or androgynous." But I also hear you feeling very attached to someone being "a man" in the way YOU see that, which seems like it may be in conflict with that, if you follow me.
But it may also be that you just have a lot to unpack around masculinity still? And maybe around your orientation, also? In other words, you make clear you only feel attracted to men and people who identify as men, and feel uncomfortable when you feel female or feminine around them. Can I ask how/if you identify your sexual orientation? Do you identify as heterosexual or not?
Member # 49145
Sorry for the delay! Yeah I see what you mean... I think I do think in very binary ways but I think much of this has come from society/seeing it with my parents etc. As far as I'm aware I am straight (as a female) but then even that depends on how I identify as myself! Wow, now I feel more lost than ever lol.
In terms of my current love interest, I think what I find hardest to deal with, is not how I perceive him (sensitive, soft, loving) but how he sees himself - as I say he seems to identify quite strongly with what it means to be a "real" man if you get me? this is where the conflict lies because I don't get this at all... like I don't understand the need to prove oneself by being a "man"
Member # 49145
to be honest I just feel lost with society as a whole... because I've never really understood gender, it just seems like an act.
Member # 3
Well, some of gender absolutely can be performance, and we do know that gender is about social constructs. However, many people, if not most, have some internal sense of how their own gender feels, just like even though race is also a construct, many people have an internal sense of that, too.
But there aren't any "real" men or "real" women unless what we mean by real is just that being a man or a woman, whatever that means, feels real to someone. My friend Hanne Blank wrote an amazing piece just last week about "real" women that might be a goodie for you on this:
Not all men feel the need to prove they are men, or male or to prove their masculinity. And again, not all men share the same ideas about what it means for them to be men or masculine in the first place.
When I was growing up, my Dad carried a bag that people always interpreted as a purse. Like him, I never quite got what makes a bag a bag and a purse a purse: isn't a purse a bag? But despite that, and people giving him crap about this purse/bag he LOVED (it was a thing of serious art, I remember) around masculinity, my father never took the bait, in large part because unlike some people who thought differently, he didn't see how what kind of bag he carried had anything to do with his masculinity. And knowing my dad, and a good deal about his masculinty and sense of it, I'd be inclined to say that for him, that bag was actually part of his sense of masculinity. On the other hand, another guy might very much feel differently, either about my Dad or about himself.
Member # 72864
I totally agree with your statement on how gender seems like an act. I mean, think about it: What makes you female/male? Some would say that I'm male because I have a penis -- biologically, that's true.
But what if I wanted to play the female gender role? In our society of labels and sorting, wouldn't that make me a woman?
I honestly think gender is a preconceived image that is placed upon us from the moment we are born. When I was a baby, all of my clothes were blue (the modern day color representing childhood masculinity -- interestingly, pink used to represent masculinity while blue represented femininity, but that's really beside the point) while my sister's clothes were pink. Mine had little lions on them, hers had little sheep and butterflies and flowers.
From the beginning, I was told that I was supposed to be a man. Does that mean I will be one in the conventional sense? Possibly. If I was with a woman like you, so willing to reject the traditional gender roles, I'd fall into a -very- feminine form of myself that I actually feel more comfortable and happy in.
With a more traditional 'feminine' woman, who is very much sure that she is happy with her role in society, I would likely take a much more traditional role.
Gender role, to me, has varied between partners. Because what is gender role when you have nobody to compare yours to?
Member # 49582
I really like what you wrote there, Brennan, really well put.
Member # 56822
I agree.
Jacob at Scarleteen
Member # 66249
"Gender role, to me, has varied between partners. Because what is gender role when you have nobody to compare yours to?"
I really agree with this it feels to me as though relationships are their own little system of identity and language. I think one of the hardest things about understanding gender and relationships is that every relationship brings with it change but we try to understand what our gender identity/orientation IS, rather than thinking of gender as simply a big mix of cultural signs that we end up entering into and have a different influence on every unique combination of unique people in relationships.
[ 10-05-2011, 11:19 AM: Message edited by: Jacob at Scarleteen ]
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Handbook of Venous Disorders : Guidelines of the American Venous Forum Third Edition
Peter Gloviczki, Michael C. Dalsing
Taylor & Francis, Dec 26, 2008 - Medical - 744 pages
Now in its third edition, the Handbook of Venous Disorders continues to provide comprehensive and up-to-date information on acute and chronic venous and lymphatic diseases and malformations and to discuss the latest knowledge on epidemiology, pathophysiology, clinical evaluation, diagnostic imaging, medical, endovascular and surgical management. This revised, updated and expanded edition takes account of all the recent developments in these areas. New chapters on, for example, foam sclerotherapathy, radiofrequency treatment, laser treatment and open surgical reconstructions are included, as well as useful diagnostic and treatment algorithms for the various conditions that are dealt with in the book. Clinical guidelines are provided in each chapter, together with evidence scores to help the reader assess the recommendations. The Handbook of Venous Disorders is written and edited by leaders and founding members of the American Venous Forum, a society dedicated to research, education and the clinical practice of venous and lymphatic diseases. The Handbook also includes several international authors, all of whom are experts in venous disease, most being regular or honorary members of the American Venous Forum.
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BASIC CONSIDERATIONS OF VENOUS DISORDERS Edited by Michael C Dolsing
The physiology and hemodynamics of the normal venous circulation
The physiology and hemodynamics of chronic venous insufficiency of the lower limb
38 other sections not shown
Other editions - View all
Handbook of Venous Disorders, 2Ed: Guidelines of the American Venous Forum
Peter Gloviczki,James S. T. Yao
No preview available - 2001
Common terms and phrases
ablation activity acute aneurysm anticoagulation arterial associated bandage blood calf catheter CEAP cell chronic venous disease chronic venous insufficiency clinical complications compression D-dimer deep vein thrombosis deep venous thrombosis Dermatol diagnosis distal duplex ultrasound edema endovascular endovenous evaluation femoral vein fibroblasts filter foam follow-up Gloviczki graft guidelines healing hemodynamic heparin iliac vein iliofemoral imaging increased inferior vena cava injection JVasc JVascSurg laser leg ulcers lesion ligation limbs LMWH long-term lower extremity lymphatic lymphedema malformations obstruction occlusion patency patients perforating veins phlebectomy popliteal post-thrombotic pressure primary prophylaxis protein proximal pulmonary embolism recanalization recommend recurrent reflux renal reported risk factors saphenous vein sclerotherapy segment skin stent Surg surgery surgical symptoms syndrome technique telangiectasias therapy thrombolysis thrombophilia thrombotic thrombus tissue trauma treated treatment trial valve valvular varicose veins Vasc vascular vein wall venography venous insufficiency venous system venous thromboembolism venous ulcer vessels warfarin wound


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When Barcelona meet Real Madrid the biggest subplot is the battle of Lionel Messi v Cristiano Ronaldo.
Ronaldo is the world's most expensive player, Real having signed him for £80million in the summer of 2009. Prior to that, in 2003, he signed for Manchester United from Sporting Lisbon as an 18-year-old.
They are two of the highest paid soccer players in the world game; Messi has a release clause of £203million and his rise to the top could not contrast more starkly to that of Ronaldo.
The Argentinean left Newell's Old Boys for Barcelona at the age of 13, with the club paying for treatment on a growth hormone deficiency that threatened to stunt his progress. In 2012 he became the club's record goalscorer at the age of just 24.
Each player has won the World Player of the Year award, and has scored in a Champions League final.
"Ferrari with a Porsche"Ronaldo says it is like comparing a , but who is the best?
Messi vs Ronaldo: finishing with feet
Messi is very much left-footed and finishes most of his chances off on that side. He generally occupied the position on the right side of attack after Josep Guardiola took over as Barcelona coach in 2008, but has featured more centrally as time has gone on. Messi is outstanding in one-on-ones, capable of the subtle dink over an advancing goalkeeper, a curled effort into the corner or a piledriver.
So many chances come his way in a team that dominates most games that he will miss a few, but it is hard to find fault in Messi's finishing. 9/10.
8/10Where Messi generally favours brains over brawn when faced with the whites of the goalposts, Ronaldo more often than not opts for sheer power. Unlike Messi, the Portuguese star is right footed, but is also adept at finishing on his weaker side. Can be guilty of profligacy, but his goals record speaks for itself. .
Messi v Ronaldo: headed finishing
6/10Messi memorably scored the second goal against Manchester United in the 2009 Champions league final with his head. But that was the exception to the rule, and most of La Pulga Atomica's (The Atomic Flea) goals come from his left foot. .
8/10Ronaldo scores far more goals with his head, not afraid to go in where it hurts. At 1.85 meters, Ronaldo is always going to be more effective in the air than Messi, who stands at 1.65. Ronaldo manages to apply great power to his headers and undoubtedly scores higher in this category. .
Messi v Ronaldo: free-kicks
Messi is capable of producing exquisite set-pieces that bend past opposing goalkeepers. His free-kicks are again more about finesse than brute force. He perhaps lacks the variation of Ronaldo. 8/10.
9/10Ronaldo's swerving free-kicks are a thing of beauty. When playing for Manchester United, he revealed that he uses the technique of striking the ball on the valve to get more power and movement. He is also capable of the classic curling free-kick. .
Messi vs Ronaldo: dribbling & control
10/10Messi is the dribbler extraordinaire and there is no one better in the world at taking on and beating players. The beauty of Messi is that it is not just his pace that takes him past defenders, but his sublime technique, quick feet and balance. He is not the strongest or quickest player in the world, but relies on natural ability to take him past his man. .
9/10Few players can perform a step-over like 'CR7', and it is such skill that helps him beat opponents repeatedly. Ronaldo's control is generally excellent, but he relies more on his pace to take him past players than his Argentinean counterpart. .
Messi vs Ronaldo: skill & technique
10/10Such is Messi's skill that the ball can appear glued to his feet as he manoeuvres himself out of tight situations and finds teammates when it seems he is surrounded. Messi, like Ronaldo, can use the backheel to great effect and also has a penchant for looping the ball over a defender and collecting it on the other side. .
9/10Ronaldo is more of a showman than Messi and can take the breath away with his array of step-overs and flicks. But in some matches, when the step-overs are taking him nowhere and he is attempting backheels that are not finding team-mates, Ronaldo stands accused of producing style over substance. He is blessed with tremendous natural ability and when on song he is a joy to watch, but he has more ineffectual matches than Messi. .
Messi vs Ronaldo: team play
9/10One of the reasons Messi has been more successful at club level than international level is that he dovetails so beautifully with Xavi Hernandez and Andres Iniesta. His chemistry with these two is a beauty to behold and there is no one at Barcelona who claims that Messi does not work hard enough or combine well with his teammates. .
6/10Ronaldo is a player almost beyond reproach but one of the gripes that some teammates have had about him – and certainly sections of the Real Madrid support – is that he can be selfish and too obsessed with making the difference on his own. Ronaldo has been known to shoot from ridiculous angles and distances when teammates are better placed, and will often try to score when there is a superior option to his left or right. Some Real fans have made their frustrations known, and Ronaldo has actually been whistled at the Bernabeu for his individualistic approach. He also has a tendency to show his frustration and petulance towards teammates. .
Messi vs Ronaldo: physical prowess
7/10Messi is not a big man and can be knocked off the ball by more imposing opponents. However, he is also well capable of holding his own in one-on-ones and often it takes a foul for a defender to knock him off the ball. .
9/10Ronaldo is a real specimen of a man and has previously claimed to do 1000 press-ups a day as he looks to maintain his washboard stomach. He is a physically imposing player with unquestionable fitness and professionalism in looking after himself. .
Messi vs Ronaldo: Stats
A statistical comparison of club and country games, goals and assists since Ronaldo moved to Real Madrid in 2009.
2009-10 - Games:64 Goals:49 Assists:11
2010-11 - Games:61 Goals:51 Assists:22
2011-12 - Games:68 Goals:74 Assists:27
2009-10 - Games:39 Goals:33 Assists:7
2010-11 - Games:65 Goals:56 Assists:16
2011-12 - Games:73 Goals:77 Assists:16
Messi vs Ronaldo: Goal Totals
Over the past six seasons, the players' cumulative goal returns for club and country have been similar. Ronaldo has often been moved higher up the pitch and into a more central position as his career has progressed, while Messi is now commonly deployed by Barcelona in the position he can hurt opponents most: at the centre of the attack. He, like Ronaldo, played deeper earlier in his career but coaches such as Sir Alex Ferguson, Jose Mourinho and Josep Guardiola realize that when you possess a player of the class of either of these two, it is wise to position them where they can do the most damage. 10/10 for both.
Messi exerts more influence over more games. Ronaldo has been accused of being a 'flat track bully' in the past, effective in the lesser matches but disappearing when it really matters. This may be a harsh assessment, but Messi has produced more performances in the biggest games. The Argentinean scores one more point than the Real Madrid man and edges the battle of Messi v Ronaldo.
Lionel Messi: 69/80
Cristiano Ronaldo: 68/80
DISCLAIMER: This article has been written by a member of the GiveMeFootball Writing Academy and does not represent the views of GiveMeFootball.com or SportsNewMedia. The views and opinions expressed are solely that of the author credited at the top of this article. GiveMeFootball.com and SportsNewMedia do not take any responsibility for the content of its contributors.
Do YOU want to write for GiveMeSport? Get started today by signing-up and submitting an article HERE: https://www.givemesport.com/writeforgms


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West Henderson High journalism team shines at quiz bowl
Journalism students from West Henderson High School won the National Journalism Quiz Bowl at the National High School Journalism Convention in San Antonio, Texas, held Nov. 15-18.
Team members were seniors Diane Gromelski, Jillian Heywood, Hailey Johns and Sarah Wood. Heywood and Wood are editors of the 2013 Westwind yearbook. Gromelski and Johns are editors of the Wingspan student newspaper. More than 20 schools from across the United States competed in the quiz bowl.
West Henderson had 12 journalism students attend the convention with publications adviser Brenda W. Gorsuch. Four of the students won awards in the national write-off competition. Johns won a superior award in newspaper layout. Wood won a superior award in yearbook cover/endsheet design. Senior Erin Wiley won an honorable mention in student life copy. Heywood won an honorable mention in yearbook page design.
The Wingspan won the Best of Show Award for eight-page broadsheet newspapers from schools in attendance at the convention. The Westwind won eighth place in Best of Show for yearbooks.
Local students are accepted to Coastal Carolina
CONWAY, S.C. — Hendersonville High School students Brittany Robinson and Cam Edwards and West Henderson High's Hannah Watts have been accepted at Coastal Carolina University for the 2013 fall semester. Robinson plans to major in graphic design. Edwards plans to major in marketing.
Savannah College of Art and Design dean's list
SAVANNAH, GA — The Savannah College of Art and Design announced the dean's list for the 2012 fall semester. Full-time undergraduate students who earn a GPA of 3.5 or above for the quarter receive recognition. The following local students were named to the dean's list:
Fletcher: Shelby Katz and Solomon Petchenik.
Hendersonville: Alexander Zinni.
Zirconia: Devon Head.
College News: West Henderson High journalism team shines at quiz bowl
West Henderson High journalism team shines at quiz bowl


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April 29, 2005
FULLERTON, Calif. -
UC Santa Barbara (19-22, 1-6) dropped its fifth straight game after falling 9-1 to defending national champion Cal State Fullerton (31-11, 9-1) on Friday night at Goodwin Field.
Only three Gaucho hitters managed to safely hit their way onto the base paths against Titan starter Ricky Romero (9-4). Romero threw eight strong innings, allowing one run in the first inning and blanking the Gaucho offense for the next seven before handing the ball over to Jared Clark to start the ninth.
The Gauchos struck early but not often in Friday night's game. UC Santa Barbara pushed across its only run of the contest in the top of the first to take an early 1-0 lead. After shortstop Alden Carrithers struck out to lead off the game, senior David Figoni drew a walk on four straight pitches. Right fielder Matt Wilkerson followed with a single into left field to put runners on first and second. After a Jack Pinkerton walk, junior Bill Rowe picked up the only Gaucho RBI with a groundout to first base.
The Gaucho lead proved to be short lived. Fullerton quickly erased the deficit by scoring four runs of its own in the bottom half of the first inning. Titan leadoff hitter Blake Davis sent the first pitch he saw from Gaucho starter Steve Morlock into left field for a single. Following a sacrifice bunt, Sergio Pedroza put runners on the corners with a single to left field. After the single, Morlock hit Fullerton's cleanup man Brett Pill to load the bases. Left fielder Danny Dorn cashed in for the Titans with a base hit back up the middle to knock in two and give Fullerton the lead. After a sacrifice fly and a balk that moved Dorn to third base, second baseman Matt Stevens committed an error that allowed the fourth and final Titan run to cross in the inning.
Following a scoreless second inning, Fullerton increased its lead over UCSB in the third. Pedroza started the inning with a single to right field, and Pill parked a 1-2 offering over the wall in left field to extend the Titan lead to 6-1. Fullerton would once again tally two runs in the fifth inning. Dorn picked up his third RBI and second run scored of the contest after doubling home Pill and crossing the plate on a Trevor Mortensen single to make the score 8-1 in favor of the Titans. Fullerton would strike one last time in the eighth inning on a sacrifice fly off the bat of John Curtis.
Although he tossed a complete game, Morlock picked up the loss for the Gauchos and fell to 4-7 on the year.
The Gauchos and Titans will face off again at Goodwin Field tomorrow at 6:00 p.m. Michael Martin (4-4) is slated to be on the bump for the Gauchos and Wes Roemer will throw for Fullerton.


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So what if I'm on an MST3K kick this weekend? Is there any better kick on which to be?
Hal asked:
When Hand of Light triggers for my ret paladin, the icon for Divine Storm lights up on my bar. As far as I can tell, though, Divine Storm doesn't interact with Holy Power in any way. Is this a bug, or am I missing something?
Divine Storm originally dealt damage based on the number of holy power charges you had, but that was changed. It just hasn't been removed from the spell alert list for Hand of Light yet.


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OXFORD - Heroin is a problem everywhere, including Chester County. The latest Town Hall meeting in Oxford on Wednesday drew a large crowd ranging from teens to seniors to hear more on the subject of drug abuse in the community. At the center of the presentation was Andy Rumford, who lost his daughter Kacie to heroin and has responded by founding Kacie's Cause, an organization that tries to save lives.
Kacie Rumford died in the spring at the age of 20 in her Kennett Square home. Before she was buried, the www.kaciescause.com website was up and running. In the eight weeks since, the site has had nearly 10,000 hits and similar town halls are being planned throughout the region. In addition, chapters of Kacie's Cause are already being founded in several states and Canada.
"Kacie always wanted to change the world and now she does," Rumford said.
The Kacie's Cause chapters are helping increase awareness of the scope of the heroin problem, educate families and friends of users on how to know when someone is using heroin or other drugs, and what resources are available. The town hall meeting at the Oxford Presbyterian Church Hall showed that people want to learn more, and do something, organizers said.
"I knew we would have a good turnout but never in my wildest dreams did I think we would fill this fellowship hall," said Oxford Mayor Geoff Henry, who organized the event after attending a similar meeting May 4 at the Longwood Fire Company. Henry explained that at the end of that meeting he was told by Rumford, "My daughter used to make frequent trips to your borough to buy heroin."
The fact that the drug is readily available and inexpensive leads to its broad appeal. The fact that the church where the meeting was held is also the site of regular Narcotics Anonymous and ALANON meetings attests to its presence.
"The drug is here and has been here for years, and the proliferation is staggering," Rumford said.
Rumford said 36,000 lives a year are lost to drug overdoses in the U.S.
"From statistics, we know that of users that don't seek treatment in rehab, 90 percent will die (of their addiction)," he said, warning that everyone needs to be aware of warning signs. "Change your thinking or you may bury your child."
Members of the audience stood and gave their insights from all sides of the issue. There were drug counselors as well as recovering addicts and people who have suffered as family members have fallen victim to heroin.
There were harrowing stories like Rumford's, as well as uplifting stories from people in recovery. Most had both highs and lows to speak about.
One resident stood to tell how he was a child in an alcoholic home, became a drug user, has been clean for eight years but is now dealing with his son's addiction.
The Town Hall was about more than education, it was also about change. Mention was made of State Senate Bill 1147, called Good Samaritan legislation, that protects someone from arrest for their own drug use if they call 911 for an overdose victim. That bill appears dead, but the audience was asked to contact their legislators to tell them they want it revived.
The audience was also encouraged to support House Bill 317, which would set up a system between pharmacies so one person could not fill multiple prescriptions at the same time.
The meeting wrapped up with a quick overview of the Kacie's Cause Web site where a list of resources, information and other Town Hall events can be found.
The conclusion of the meeting held more news: An Oxford chapter of Kacie's Cause has been formed with resident Kristin Gent serving as the group coordinator.


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Wall Art in Commons Makes Campus Plan Common Ground
By Michelle Marasch Ouellette
February 2014
SUNY Plattsburgh has a plan.
And now, evidence of that plan has taken over a wall of Flynt Commons, otherwise known to alumni as the Blue Room.
Nearly 83 feet of graphic design cover that wall from floor to ceiling and announce the "Big Plan on Campus" and its priorities:
- Strengthening Support for Student Success.
- Promoting Teaching Excellence.
- Expanding Opportunities for Experiential Learning.
- Increasing Global Experiences and Multicultural Competencies.
- Building Community Connections.
- Cultivating a Culture of Continuous Improvement.
Big Design, Big Plan
Click here to see a 360 degree view of today's Flynt Commons.
"The design is big because the Campus Plan is big," said Provost and Vice President for Academic Affairs James Liszka. "It was developed after a yearlong process and more than 45 focus groups both on and off campus, so we think it really reflects who we are and what we're about. It is our map to fulfilling our potential, and, if we are to truly follow that map, we need these priorities kept front and center in the minds of faculty, staff and students.
"Given this central location, this graphic design will help us do that. We think it's tasteful and communicates the message well: SUNY Plattsburgh is all about student success."
Measuring Up
The graphics were designed by Sarah Richard '02, assistant director of creative services at the college. Richard said that the whole Marketing and Communications Office played a role in the project, brainstorming and helping to come up with ideas.
Then, she and Executive Director of Marketing and Communications Bryce Hoffman took a tour of the campus. Hoffman noticed the wall, and the ideas fell into place.
To learn more about the Campus Plan visit http://bit.ly/PlattsPlan.
Additional Photos
Contact Information
To learn more about academic programs at SUNY Plattsburgh, you can browse our directory of academic departments and programs or contact:
Phone: (518) 564-2040
Toll-Free: (888) 673-0012
Fax: (518) 564-2045
Email: [email protected]


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KANSAS CITY, Mo. (AP) -- Joe Mauer hit a grand slam and Chris Parmelee added a three-run shot and the Minnesota Twins outlasted the Kansas City Royals 8-7 to complete a sweep of a doubleheader Saturday.
Justin Morneau drove in two runs and Minnesota rookie Cole De Vries beat the Royals 3-1 in the first game.
Mauer's grand slam in the second inning of the nightcap was the third of his career and the first by the Twins this year. Mauer's ninth home run came after Pedro Florimon's double was sandwiched around walks to Drew Butera and Ben Revere.
Parmelee homered in the first with Alexi Casilla and Josh Willingham aboard.
Luke Hochevar (7-13) lasted just 1 2-3 innings, the shortest outing of his career. Hochevar faced 14 batters, 10 reached (six hits and four walks) and eight scored before he was replaced by Everett Teaford, who threw 5 1-3 scoreless innings.


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BOOM video 2430
Fable III will be set in a Napoleonic-styled period of Albion, and will allow players to take on a King-like role in influencing the world, according to Eurogamer.
"I think there's something fundamentally wrong with RPGs like Fable," said Molyneux. "It's a mechanic that's been there since the eighties. I'm going to take that foundation stone and throw it away."
Players will begin the game as the offspring of a hero from Albion's past, gradually becoming powerful enough to exert their will over the world. Eventually, players can "use gold to build up a certain region, help poorer people, let people off taxes and so on," he said.
The game will take place some 50 years after the events of Fable II, and according to Molyneux, some characters from the previous game will return in Fable III.
Molyneux also tied the story in to the splash images of famous rulers recently seen on the Lionhead website.
"What promises are you going to make to become ruler, and then how many of those promises are you going to keep?" asked Molyneux. "You can see with Tony Blair and Obama that it's very easy to make promises and be a rebel. If Che Guevara had lived to deliver on his promises, if he had ruled, would he have been that wonderful amazing person? There's many examples in history of rebels who once they get power, they go bad a bit. This time in Fable, you're not a hero whose only power is in his sword. There's a certain point in the game where you have the power to rule, so how are you going to use that?"
nope "We've loosely chosen the Napoleonic period, and we've started to pull in a bit of Regency, a tiny bit of Victorian, and we're plugging in an early industrial age to Albion," said lead artist John McCormack. "It's a Napoleonic fairytale."
Added McCormack: "One of the main themes here is how the advancement of the new world is having an adverse effect on the beautiful lush environments of Albion. Industrialisation is changing Albion, and do you want to put a stop to that?"
Fable II will also soon be split into five downloadable episodes, all of which will be available on September 29. The first chapter will be free, with players having the choice to buy subsequent episodes after completing it. The episodes will be compatible with both the Knothole Island and See The Future DLC packs.
Fable III is set for a 2010 release, though not early in the year, according to Molyneux. Holiday sounds like a good bet.


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crisis averted
erm, sorry about that last post there. it did let up after a while and i was able to sleep after trying the whole (Internet videos + hot bath with sleeping aid oils) thing suggested here. i'm pretty sure the cause is just stress since my first exam is tomorrow, the rest all happen in the same week and i am totally unprepared for any of them. i guess at least it gets them all out of the way quickly. after they're done i can start focusing on what to do about housing.
regarding "get to a psychiatrist rite nao!!!", i already have one and his office is shut at 2am no matter how crazy i am. i didn't want to call NHS 24 after the result i got last time, which was the on-duty staff insinuating that i was a crackhead, refusing to believe that i wasn't in treatment for heroin use, and repeatedly telling me they would not give me any morphine or methadone (i had not asked for any kind of drugs). i will let Dr. D know what went down when i see him next on the 24th.
i really appreciate the comments from people trying to help, too. it helps to know people are out there and they're not all judgmental dicks. there's not a whole lot of people i can call or whatnot when this kind of shit happens - my parents are too far away to do anything about it, so all it would do would be scare the crap out of them for no reason, and i didn't wanna wake either them or my one other friend Feoa up at that hour of the morning just to listen to Cracky McGee blabber on about shadows and imaginary singalong time.
gotta go "revise" now, but will be connected for the rest of tonight up through the morning if anyone writes back. carpe corporem


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This week MinneCulture presents youth poets from across the Twin Cities. The Capri Theater in North Minneapolis stages an open-mic event on the first Monday of every month. Recently, young people participating in the Brave New Voices international youth poetry tournament performed to a full house. Hear their passion and connect with this new generation of poets, coached by local poet/educator Guante, and hosted by hip-hop/spoken-word/community advocate Tish Jones of TruArtSpeaks.
MinneCulture airs every Wednesday from 7:30-8pm. This program was produced for KFAI by Daniel Zamzow, and is made possible by the Minnesota Arts and Cultural Heritage Fund.


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Fiery Braves rally to cut magic number to 2
Uggla, J. Upton dingers put Atlanta ahead after Fredi, Wood ejected
By Mark Bowman / 9/19/2013 12:45 AM ET
WASHINGTON -- The Braves might not have realized their wish to clinch a division title on their rival's home turf. But before exiting the nation's capital, they generated some momentum that could carry them through the regular season's final days.
After extending their recent woes while getting swept in Tuesday's doubleheader at Nationals Park, the Braves once again proved resilient as they overcame a potentially disastrous fifth inning with a three-run sixth that propelled them to Wednesday night's spirited 5-2 win over the Nationals.
"We knew we had to get this one," Braves outfielder Justin Upton said. "We struggled at home [this past weekend against the Padres]. We struggled yesterday in the first two games of the series. This was a big one for us today and the guys stepped up."
Craig Kimbrel's perfect ninth inning allowed him to exorcise the demons that haunted him when he surrendered a career-high three runs in the ninth inning of Tuesday's twin bill. More importantly, it allowed the Braves to reduce their magic number to clinch the National League East to two with 10 games remaining.
While the Nationals still have a chance to claim an NL Wild Card entry, their bid to win a second straight NL East title was damaged in the process of losing 13 of the 19 games played against the Braves this season.
"We've got to learn how to finish," Upton said. "That's one thing you've got to learn how to do, to finish. Until we win these next two and this thing is over with, it's not done. So we've got to finish."
Dan Uggla began the decisive sixth inning with his first home run since July 25, and Upton capped it with a two-run shot that proved to be the third-game winning home run he hit against the Nationals this year. The sudden offensive eruption against Ross Ohlendorf, who had faced the minimum through the first five innings, occurred immediately after the usually composed Alex Wood had two fiery exchanges with home-plate umpire CB Bucknor during Washington's two-run fifth inning.
"I feel like I'm usually as composed as you could ask anyone to be out there," Wood said. "It's one of things where every now and then, this game can kind of get you. Tonight was one of those nights."
While Wood might not want to repeat his actions, they certainly seemed to provide a necessary spark to the Braves, who had slumbered while losing nine of their previous 13 games.
"I don't know if that's what happened," Wood said. "But it definitely makes me feel a little better that they scored some runs and we ended up winning the game. There is no doubt tonight was a huge win for us. Hopefully how we played the last half of that game will translate to how we play the rest of the season going into the playoffs."
Wood's eruption occurred after he battled Jayson Werth during an eight-pitch at-bat that concluded when Bucknor ruled a 3-2 fastball missed the inside edge of the plate. The resulting bases-loaded walk accounted for the game's first run and led the rookie pitcher to bounce off the mound and begin shouting at Bucknor.
Manager Fredi Gonzalez rushed toward the plate and was ejected while attempting to make sure Wood stayed in the game. But the young southpaw's night ended when Bryce Harper followed with a sacrifice fly that gave the Nationals a 2-0 lead.
As he walked toward the dugout, Wood had some more heated words for Bucknor that earned him his first career ejection.
"It definitely brought some energy to us," Upton said. "He was out there grinding for us and battling. Obviously he thought he had made the big pitch for us. It didn't happen for him. He was fired up. We knew he wanted this one and we all wanted it, so we had to go get it."
It did not appear the Braves were going to get it before Uggla drilled the first pitch of the sixth inning deep over the left-field wall. Jordan Schafer followed with a bunt single that Ohlendorf fielded and then shot-putted down the right-field line. This sequence of events quickly shifted the momentum in the favor of the Braves.
Uggla's home run was his first in a span of 101 at-bats dating back to July 25. His struggles since returning from LASIK surgery in late August had kept him out of the starting lineup for eight of the previous nine games. But the veteran second baseman showed some promise while notching a hit in each of the three games played during this series.
"We've seen him get hot, and hopefully, he's getting hot at the right time," Gonzalez said.


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STATE CENTER — Four seniors took the floor for the final time in Collins-Maxwell/Baxter's regional match against West Marshall on Tuesday. Although they did not come away with a win to continue the Raiders' season, they gave the Trojans all they could handle in the four-set loss.
CMB fell 25-27, 25-20, 25-13, 25-12. Despite being swept by the Trojans in two previous matches this season, CMB came out ready to play, taking the first set 27-25.
The set went back and forth early on with kills and blocks by senior Abbie Haupert, who has been the team's leader for the past two seasons. With the set locked up at 17-all, Haupert powered home a kill to give the Raiders a lead. Sophomore Payge Jurgens blocked a ball later on to take a 20-18 lead.
Alex Hiavacek scored on a kill to go up 22-18. Errant serves got the Trojans back in it at 23-22. Hiavacek scored to take a 24-22 edge. Two balls into the net made it 24-all. Haupert had her attempt blocked, but the ball landed wide to give CMB a 26-25 lead. A double hit by the Trojans ended the set.
CMB and West Marshall traded points in the beginning of the second set. Hiavacek put away a kill to tie it up at three. Haupert followed up to take a 4-3 edge. The very next serve landed long to tie up the score again. Abbey Applegate scored one of her three aces to start a run for CMB. Haupert had back to back aces to give the team a 12-5 lead.
West Marshall called a timeout, and it turned out to be a well-used one. The Trojans came out on a heater, scoring seven straight points to tie the score at 12. Hiavacek pinpointed a kill in the corner to give CMB a 14-12 lead, but the Trojans fought back to tie at 15. Senior Hannah McWhirter scored on a strong serve to tie it up at 18. W. M. went on a run from there, closing out the set on an ace by senior Jennifer Davis.
The final two sets were far less competitive than the first two. CMB took an early 3-1 lead on a kill by Haupert. W. M. came back to take a 5-4 advantage.
Jurgenns had a block to tie it at seven, but the Trojans got ahead and would not look back for the remainder of the set, or the match for that matter.
Despite kills by Hiavacek and Jurgens, along with a couple more blocks by Haupert, CMB fell 25-13 and 25-12 in the last two sets. The Raiders were unable to return several strong aces by Trojan junior Mackenzie Coberly.
The match ends a roller coaster type of season for the Raiders. CMB went on several runs during the year, the best of which came at the end of September, when the Raiders took four straight matches, all within the Heart of Iowa Conference.
Haupert finished the season ninth in the conference in kills with 187 and 10th in blocks with 49. Applegate was third in the conference with 53 ace serves.
She landed 88.6 percent of all her serve attempts and averaged .76 aces per set played. Jurgens was not far behind her teammate, landing sixth in the conference with 49 aces. She connected on 91 percent of her attempts. Mackenzie Schmitz was fourth in the HOI in assists with 330.


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Android users who are running CyanogenMod 10 or CyanogenMod 10.1, and probably many other custom ROMs, looking to clean up their device's display by getting rid of the notification bar now have an option to achieve that goal. Best of all, the solution ensures the user can still swipe down from the top edge of the screen to get access to their notifications. This feat was accomplished by XDA Developers forum member enryea123 through some tweaks to the SystemUI.apk and framework-res.apk files. According to enryea123, this solution will eliminate the ability to pull down the notification bar from the lockscreen. All of the changes can be undone just by restoring the stock apk files.
The guide that walks you through the process can be accessed on the XDA forums using the source link below.
source: XDA Developers Forum


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By Tiernan Ray
I'm at CES Unveiled, which serves as the annual staging ground for journalists at the Consumer Electronics Show. As they mill around the ballroom at the Mandalay Bay, eating free shrimp and as much free booze as they like, they have the opportunity to kick the tires on some of the gadgets that will appear on the floor of the Las Vegas Convention Center when it opens on Tuesday.
Health is a big topic this year. Among the connected gadgets are a spoon and a fork from Hapilabs, of Key Biscayne, Florida, each costing $99, that will surprise you with a buzzing vibration if you raise the implement to your lips too frequently. It's meant to help you cut down on your weight gain by slowing your eating, and also defray adverse gastrointestinal phenomena. The spoon or fork connect via Bluetooth to the Web to record all your eating, and Hapi providers a coaching service to help you meet fitness goals.
Among the many exhibitors showing off renewable or clean energy approaches was Eton, which makes rugged, solar power speakers you can take with you on your next trip.
Right next to Eton is GoalZero, which makes consumer solar panel kits. In the picture, you can see a small battery pack that sells with its own solar panel. You can juice up the panel during the day time and then detach the battery and take it with you.
It will give you one full recharge of your smartphone, for example, or about halfway recharge your tablet computer. It sells for $129. A larger pack, weighing in at 1 lb, will recharge your tablet completely, or give you about 3 or 4 times recharge of your laptop computer, for $509.99.
If solar is not your thing, Lilliputian Systems, a venture spun out of research at MIT, was showing off the $299 fuel-cell powered backup battery it developed for Brookstone. The pocket-size device, which goes on sale this summer, but which can be pre-ordered this week, gives you two to three weeks' worth of change for your gadgets before you need to purchase another fuel cell cartridge for $9.99.
If you can't wait for Google's (GOOG) Google Glass project for wearable tech, there's Vuzix, of Rochester, NY, which was showing off its headset prototype that displays whatever is on your smartphone screen. It also has a camera so that if you jump off a building, the final moments can be captured for posterity. The device is expected to retail for "under $500," a representative said. The model shown at Unveiled was not a working model. However, the company will show a working model on the show floor this week, they said. It's expected to become available this summer.


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The Bengals finished off their first perfect home season in 25 years Sunday and first at Paul Brown Stadium when the defensive fittingly picked off Ravens quarterback Joe Flacco three times in the fourth quarter, the last a 21-yard pick-six by cornerback
It was the sixth defensive TD in a home season dominated by defense.
Despite a career-high four interceptions and a 62.2 passer rating, quarterback
They only had to convert one third down on the drive and running back
Dalton did the honors himself with a one-yard touchdown run off a zone read that faked Ravens outside linebacker Terrell Suggs out of his spikes on the left edge, a device the Bengals used often Sunday as they tried to compensate for their injured tight ends. Then when right end
But the Bengals missed the chance to drive a stake into the defending champions when they continued to try and pass the Ravens into submission. Green-Ellis had a tremendous second and third effort for an 11-yard run that put the Bengals on the doorstep of a 17-point lead with less than nine minutes left. But BJGE was then removed from the game and on first down Dalton tried to hit wide receiver
Yet enter Kirkpatrick. With the Ravens desperate, Flacco threw his second interception on fourth-and-10 against a blitz and Kirkpatrick, playing centerfield, hauled it in at the Bengals 16.
With a 17-6 halftime lead, the Bengals let the Ravens back in the game when Dalton threw his third interception of the day to set up a field goal and new punter
And when Ravens running back Ray Rice beat linebacker Vinny Rey to the left pylon on a sweep on a two-point conversion the game was tied at 17 with 5:13 left in the third quarter. The Ravens got a life when the first two-pointer was negated on Crocker's holding penalty.
After an uncharacteristic lethargic start at home when the defense came to the rescue yet again in a game of twists and turns, the Bengals erased a 6-0 lead with Dalton's 53-yard touchdown pass to Green on the next-to-last play of the first quarter and it ignited a run of 17 straight points for Cincinnati's 17-6 halftime lead.Dalton's 16-yard touchdown pass to wide receiver
It was Dalton's 33rd touchdown pass of the season, eclipsing the 2005 team record of Carson Palmer and it marked the first time in Bengals history two receivers have had at least 10 touchdown passes as Jones joined Green in the club. And the throw gave Dalton the Bengals single-season passing yardage set by Palmer in 2007.
The throw to Jones capped a short-field drive that began at the Bengals 48 when the Bengals backed up the Ravens deep in their own territory. Missing their top two tight ends,
Slot receiver
Trailing 6-0, Green-Ellis executed the zone read for runs off tackle of eight and 12 yards (the latter sprung by blocks from tight end
After Hawkins downed a punt at the Bengals 1, the defense held for a short field at the Ravens 43. But after Green-Ellis ripped off a seven-yard run, Dalton threw five straight passes and had to settle for Mike Nugent's 39-yard field goal with 6:36 left in the half that made it 10-6 on his first attempt since Dec. 1.
The Ravens wasted no time ending Dalton's streak of 131 straight passes without an interception when they picked off two of his first six passes to stake Baltimore to a 6-0 lead on two Justin Tucker field goals with 2:26 left in the first quarter.
The Bengals came into the game with a 7-0 swagger at home, but the offense didn't show up on the first two series with the two turnovers, a delay of game, and a timeout at the line of scrimmage to avoid another delay of game. Plus, center
The Bengals offensive line took some shots. Collins left with an ankle injury late in the half but returned for the second half and then left, putting left guard
On the game's first snap Dalton hung up a "Go" ball to Marvin Jones down the left sideline and his tip at midfield went into the hands of cornerback Corey Graham for a 28-yard return to the Bengals 21 to stop to the no-pick streak at 131 that dated back to Dec. 1 at San Diego.
But like it has in every game during this home season, the defense took the offense off the hook with a three-and-out after stuffing the Vikings last week on all nine third-down conversions and the Ravens got Tucker's 38-yard field goal to make it 3-0 less than two minutes into the game. Bengals head coach Marvin Lewis won a challenge on second down when an incompletion wiped out a first down and safety
But the Bengals went through their trouble at the line of scrimmage before Dalton uncorked a terrible throw over the middle that skied over the head of Green at the Ravens 35 and it got picked by safety James Ihedigbo for Dalton's eighth interception against Baltimore, his most against any team.
Flacco then put together a nice drive without Rice. Bengals WILL backer
But a defense giving up 17 points per game at home refused to give up a touchdown. After Pierce slashed for four yards, Kirkpatrick and defensive tackle
When the Bengals got a lead, defensive coordinator Mike Zimmer unloaded a ton of blitzes and Flacco struggled under the pressure. It appeared that ends Michael Johnson and
Green caught four balls for 61 yards, leaving him 15 yards shy of Chad Johnson's single-season record.PREGAME NOTES:With both of their top tight ends shelved for Sunday's game against the Ravens at Paul Brown Stadium, the Bengals figure to replace Jermaine Gresham and Tyler Eifert with three- and four-wide receiver sets. Which means more of slot receivers
Also active for the second time since he rejoined the club earlier this month was backup right tackle
Also out for the Bengals are cornerback
Although a steady rain pelted Paul Brown Stadium during Sunday morning warmups, the game against the Ravens should get underway in little or no rain. The National Weather Service in Wilmington, Ohio is calling for the bulk of the rain to be over by 1 p.m. and if not it there'll only be a drizzle here and there with temperatures about 40 degress and a mere five mile-per-hour wind out of the south and west.
The rain doesn't figure to alter the Ravens game plan. They want to go deep early and often to wide receivers Torrey Smith and Jacoby Jones.
The Ravens didn't have one of their top defensive linemen, Arthur Jones, out with a concussion.
It was fitting Bengals head coach Marvin Lewis introduced the starting defense for the home finale. In going 7-0 at PBS, the Bengals have allowed just 17 points per game while holding foes to 22 percent on third down at 20-for-89.
KENNY SIGHTING: Fresh off buying a 2013 AFC North championship hat at the Bengals Pro Shop, Ken Anderson surfaced in the press box before the game praising the work of the new No. 14. Anderson, the Bengals all-time leading passer, watched last week's game against Minnesota and saw Dalton break his career high of 29 touchdown passes in a season.
"I thought he looked very good last week; very accurate and he's playing with a lot of confidence," Anderson said. "The impressive thing to me was the two back-shoulder throws for touchdowns. That takes a lot of touch, timing and accuracy."
When Anderson was asked about Dalton wearing his No. 14, Anderson joked that he better be good. On Sunday he smiled.
"I think he's doing just fine."


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July 6, 2010 > Juvenile Hall is inappropriate for young minors
Speak to anyone on the street and discover near unanimity that most minors under the age of 18 should not be placed in adult jail facilities where they would interact with hardened criminals and witness unsavory activities. This viewpoint was actually memorialized with the passing of the 1974 Juvenile Justice and Delinquency Act. This Federal law prohibited the placement of youth in adult jails except under very limited circumstances so that young minds would not be influenced by older offenders in adult jail.It is with this similar reasoning that, at my request, the Santa Clara County Board of Supervisors has adopted a policy which states that minors 12-years old and younger should not be placed in Juvenile Hall and that the county should develop local alternatives for the safe, temporary placement of children, age 12 and under, who commit a serious crime.Congregate care settings, such as Juvenile Hall, present numerous opportunities for impressionable young children to model the behaviors of their older peers who have often been through the system many times and have developed negative behaviors. As a result, rather than providing them with positive role models, a stint in Juvenile Hall actually increases the chance that the young children will become repeat offenders.That is not to say that children should not be punished for committing serious crimes; rather that children of that age are easily influenced and that the county should help guide them towards being a good citizen of society. Too often, young children who commit crimes are instantly labeled as life-long criminals but, with the right atmosphere and mentoring, they can learn right from wrong.By sending young children to Juvenile Hall, there is a risk of aggravating the trauma they are likely to have already experienced. According to the study by the County's Juvenile Justice Commission, 90 percent of the children under 13, who have been placed in Juvenile Hall from 2007 to 2009, had a history of trauma or child abuse, a diagnosed mental illness or an absent parent. Rather than correcting the behavior, the experience of incarceration will likely increase the difficulty of educating the youth on how to become a model citizen.As an alternative, the county is developing therapeutic foster homes which allow for a more positive experience for the children who have come into the system. As such, these children will be more likely to respond to the positive inputs provided by the staff in a nurturing environment and will have a greater likelihood of a positive outcome.It is believed this policy is the first of its kind in the nation. Therefore, I have also asked that the County explore working with neighboring counties to develop a policy of shared placements appropriate for children 12 years old and younger who commit a serious crime. Rather than allowing older criminal offenders to influence another generation, we can break the cycle and steer these young children on the path towards success. Also, by working with other Bay Area jurisdictions, we can design a successful program to help guide our youngest members of the community. Ideally this program will be adopted by others around the nation to truly make a difference in the lives of the generations to come.If you would like to learn more about this policy or would like to know how you can help, please contact me at (408) 299-5030 or firstname.lastname@example.com.