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By G. Asam. Samford University.
When growing intracellular and extracellular organisms order fildena 50 mg without prescription erectile dysfunction vacuum pumps australia, and in- LTBI is found in these groups buy discount fildena 25mg erectile dysfunction drugs in the philippines, it should be treated to eradicate hibits the growth of dormant organisms in macrophages and this reservoir of infection (Box 38–2) order fildena 100mg on line erectile dysfunction youtube. Radiographic techniques PTH (1–34) · Falls Metabolic Bone Disease Service, centered on dual X-ray absorptiome- Hospital for Special Surgery, try (DXA) permit a determination of New York, New York, USA bone mass and fracture risk. Beginning in 1983, this group has col- lected data from virtually all major randomised PREVENTION trials conducted in early breast cancer, published Beginning in the 1990s, coinciding with the or not. In: Freund H-J, Sabel B, Witte O, processes into motor and cognitve networks. A very slight flexion of hips and knees assures that ment that those receiving conservative treatment. Remember, as in the standing version of Ward Off, let the wrist be loose and let it lead the movement. This manoeuvre is not particularly useful for drug development but is often used in the clinical set- ting to determine continued response to drug. Wälchli B, Dvorak J (1998) Axial symptoms including cervical migraine and cervical angina. Patients with MCI generally present Thus, several strategies can be considered for with a memory complaint. Dashed and dotted vertical lines in (f ), (g): onset of the corticospinal peak and of the extra facilitation on combined stimulation, respectively. To minimize the cost of storage with large datasets, MITRA is designed to support a hierarchical storage structure consisting of either one or multiple tertiary storage devices, D disks, and M megabytes of memory (Ghandeharizadeh et al. Gabapentin should be given at least 2 hours after a dose of an antacid to decrease interference with absorption. Interactive mem- rotrophic factor in spatial memory formation and ory systems in the human brain. There is no Ia excitation from gastrocnemius medialis to soleus, There are bidirectional connections between soleus a finding confirmed using different techniques: the andperoneusbrevis(Fig. The values for CVnetwork are obtained by averaging the binned values (60 s) across all channels, followed by calculations of a new average across time for a particular experimental episode. With levodopa and dopaminergic agents, observe for im- Therapeutic effects are usually evident within 2–3 weeks, as levo- provement in mobility, balance, posture, gait, speech, hand- dopa dosage approaches 2–3 g/d, but may not reach optimum writing, and self-care ability. If the Drug Selection and Administration cough is productive, note the color, odor, viscosity, and amount of sputum. After this age, bone mass slowly, acts to increase bone resorption in response to low serum but continuously, decreases. Acids are usu- Minerals occur in the body and foods mainly in ionic form. These alterations leave patients tributes to skeletal muscle degeneration asso- with less muscle mass to perform activities that ciated with illnesses that cause cachexia. Lymphadenopathy resembling malignant lymphoma This reaction has occurred with several antiseizure drugs, most often with phenytoin. The resulting injury to the endothelium farction, heart failure, or sudden cardiac death. This is a new therapy that, following a period Several different sorts of psychological thera- of development, has now resulted in four large pies have been developed to address the follow- randomised control trials. Peroneal-induced inhibition of the on-going need to stabilise the ankle during the stance phase soleusEMGwasmuchsmalleratheelstrikethandur- of walking (see Chapter 11,p. The importance of fragility fractures, of which represent significant and irreparable damage. I am indebted to the love and support of my children and their vii viii Symptoms of Unknown Origin families: Mary Kathleen Meador, Graham K. Urogynaecology • Satisfaction Symptom relief and objective assessment of • Acceptability bladder function may not necessarily • Quality of life correspond with quality of life or • Symptom relief satisfaction. In normal subjects, an increase ease with a deficient glycinergic inhibitory system in recurrent inhibition during weak contractions is (see Chapter 5,p. The recently introduced method of electrophysiological imaging (Diogo et al.
Another method for attaching electrode arrays is by biocompatible adhesives purchase 100 mg fildena visa erectile dysfunction zyprexa. The deep peroneal-induced inhibition of the soleus Hreflex starts to manifest itself at an ISI of 1–1 order 25mg fildena mastercard erectile dysfunction medication list. The quality of evaluation in physical based on the Bobath concept in stroke rehabilita- therapy cheap fildena 150 mg line impotence at 43. Some M1 ax- nae V–VII), where they end on intrinsic in- ons from the lateral funiculus also cross the terneurons and propriospinal neurons. Acidification of urine (eg, with 3 divided doses ascorbic acid) is usually needed. In Motor Control: Concepts contribute to cyclical modulation of the soleus H-reflex and Issues, ed. Numerous medications have been used for prophylaxis, including aspirin (650 mg bid) and Acetaminophen is usually safe in recommended doses unless NSAIDs (ibuprofen 300 to 600 mg tid; ketoprofen 50 to 75 mg liver damage is present or the person is a chronic alcohol bid or tid; naproxen 250 to 750 mg daily or 250 mg tid). Why people with high blood pres- Pharmacology is the study of drugs (chemicals) that alter sure, heart failure, or diabetes take ACE inhibitors and what functions of living organisms. Each steroid was given in estimated to be about four times more potent than three doses: 200, 400 and 1000 µg b. All of these arm that does well enough graduates to Phase III, BREAST CANCER 97 and if it does sufficiently well it might even yet fully evaluable. It is often used in am- the active ingredient of curare, a naturally occurring plant al- bulatory surgical or invasive diagnostic procedures and re- kaloid that causes skeletal muscle relaxation or paralysis. For ventricular fibrillation, • Receive or take antidysrhythmic drugs accurately immediate defibrillation by electrical countershock is the ini- • Avoid conditions that precipitate dysrhythmias, when tial management of choice. During medical school and my postgraduate training, I com- pletely accepted and embraced the biomolecular model of humans and diseases and the virtual separation of mind and body. Nursing Diagnoses MAO-A and MAO-B, both of which are found in the CNS • Bathing/Grooming Self Care Deficit related to tremors and peripheral tissues. In addition, all hazard ratios are expressed as observation TRIAL SIZE, OVERALL RESULTS arm versus treatment arm ratios. With B-complex vitamins: (1) Give parenteral cyanocobalamin (vitamin B12) intra- muscularly or deep subcutaneously. The latencies of both peaks were longer after more distal stimulation: 38 vs. The constraint is a weak link; the per- formance of the entire chain is limited by the strength of the weakest link. Antiplatelet effects occur dur- mately 85% of strokes are thrombotic, the benefits of aspirin ing drug infusion and stop when the drug is stopped. Place the salmon on an 8-inch square of aluminum foil on a baking tray and close the packet. Since herbal preparations in fact are well known to be non-addictive do not have clear, definite information about the because of their gross lack of specificities. The author has chosen words and constructions with which the audience is not familiar (see jargon). Failure to do this can lead to confusion and depression as you start to believe those who tell you, for all kinds or reasons and with no real evidence, that your writing is poor (see PIANO). The RTOG it seems clear that single modality therapy has then followed that study with a study comparing limited if any impact on patient outcome. Although numerous factors affect in the rejection reaction than B cell activation and formation of graft survival, including the degree of matching between antibodies. Strong laxatives or any laxative used in excess may initiate uterine contractions and labor. Cefotaxime is primarily metabolized in the liver comitantly with an aminoglycoside or a fluoroquinolone (see to an active metabolite, desacetylcefotaxime, which is elim- Chap. They will prevent hunger, give you the energy you need for your workouts, keep you satisfied, and provide the amino acids your muscles need to recuperate after your exercise sessions. The Atrial Fibrillation Follow-up Investigation of of a defibrillator in patients with myocardial Rhythm Management (AFFIRM) Investigators. When she arrives at the office, you explain that the examination will include using medications to dilate her eyes and a test for glaucoma.
It is contraindicated in preg- A study of 212 patients with knee OA indicated that long- nant and lactating women cheap 100 mg fildena erectile dysfunction treatment penile implants. His vital signs are blood pressure (BP) 194/88 generic fildena 50mg erectile dysfunction rap, pulse 92 generic 100 mg fildena mastercard erectile dysfunction liver, respiration 18. Aldosterone is the main mineralocorticoid informed that no more corticosteroids are needed is called a and is responsible for approximately 90% of mineralocorticoid negative feedback mechanism. Subse- quently, much of the primary knowledge about the spinal circuitry has come from animal experiments, but human studies have retained a unique role: the abilitytosheddirectlightonhowspinalmechanisms are used in the control of voluntary movement. Give intravenous (IV) acyclovir, cidofovir, foscarnet, and To decrease tissue irritation and increased toxicity from high ganciclovir over 1 h. Use ings from the National Surgical Adjuvant Breast of chemotherapy plus a monoclonal antibody and Bowel Project B-14 randomized trial. It makes much more sense than putting a child back into pull-ups and having them urinate in their bed every night (the wrong goal). The issue is not only a mat- with variations in disease severity over time. In addition, the even distribution of ing command for normal movement is mediated propriospinally mediated descending excitation to through the propriospinal relay. Similarly, the correlated responses obtained from each cluster have an implication for the QUASI-RANDOMISED TRIALS statistical analysis, since standard statistical tests These are controlled experimental studies where (e. Then ask the key question: will enough people be interested enough to spend money on buying it? CHAPTER 27 ANTIDIABETIC DRUGS 389 BOX 27–3 HYPOGLYCEMIA: CHARACTERISTICS AND MANAGEMENT Hypoglycemia may occur with insulin or oral sulfonylureas. In general, combination ther- When monotherapy is ineffective, a second, and some- apy is associated with more severe adverse effects, interactions times a third, drug may be added. Include teeth that may result from drug-induced xerostomia (dry whole grains, fruits, and vegetables in your daily menu. When she is told that her chest dis- comfort is probably secondary to coronary artery disease, she cannot believe it. Walsh TN, Noonan N, Hollywood D, Kelly A, Lokich J, Chaffey J, Corson JM, Zamcheck N, Keeling N, Hennessy TPJ. The original trial, E1684, was conclusion is that salvage treatment difference unlikely to have been affected by crossover for is a possible confounding factor that limits the two reasons. Radiograph This is only considered by a Western physician if OSA is suspect- ed, in which case, he or she will consider a lateral radiograph of 26 Treating Pediatric Bed-wetting with Acupuncture & Chinese Medicine the neck or referral to a pediatric otolaryngologist for direct visuali- zation of the nasopharynx. The hippocampus lies beneath the phylogenetically more recent 244 Theodore W. Peer review The system of peer review started in the mid- 17th century when scientists decided that, before they published an article, they should ask the opinion of others working in the same field. In those years from 1962 to 1968, I did not see one pa- tient with multiple symptoms in the body benefit from psychiatric interventions, however defined. I had a tragic experience with another adult patient, who committed suicide when some in- sensitive physician had told the person outright that he was actu- ally a she. Of course, it took my entire freshman year of college for me to attribute the pains in my stomach to excessive carbohydrate consumption. Encourage your child to drink a lot during the morning and early afternoon, and restrict fluids after dinner. SEVERITY NUMBER CURED IMPROVED NOT IMPROVED Mild 25 23 (92%) 2 (8%) N/A Medium 16 6 (38%) 9 (56%) 1 (6%) Severe 44 25 (57%) 17 (39%) 2 (5%) Total 85 54 (64%) 28 (33%) 3 (3%) Discussion: Dr. Drug dosage must be carefully titrated to avoid tions, prevent hypoxia, and control other causative factors. Each paradigms to explain symptom onset and to guide of these decisions is problematic since a partially treatment. Visualization: Imagine yourself rising and falling smoothly like the water shooting from a fountain. For example, the Great Yang Stage sickness affects the exterior of the body, in addition to the small intes- tine and bladder, while the Terminal Yin Stage affects the pericardium and liver organs and strikes deep within the body. Many of the drugs described in this chapter are quite helminthiasis, amebiasis, trichomoniasis, scabies, and toxic; they should be used only when clearly indicated pediculosis (ie, laboratory documentation of parasitic infection). Identify client populations who are at risk for vitamin de- Pinkowish, M.
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In uremia, reduction and hydro- lysis reactions may be slower, but oxidation by cytochrome P450 enzymes and conjugation with glucuronide or sulfate usually proceed at normal rates. Look at papers that have succeeded and at those that have failed, and try to find out why. This is particularly true of major projects, such as scientific papers, major reports, or theses. The on-going voluntary EMG activ- Theexcitationhasadiffusedistribution(stimulation ity of ECR is full-wave rectified and averaged against of a given nerve elicits the excitation in motoneu- theconditioningstimuli. There was similar depres- also reduce the efficacy of the peroneal Ia volley in sion of reciprocal Ia inhibition from ankle extensors activating Ia interneurones. The outcome should be long the survival of this particular determined by the survival time in an patient group, the spinal metastases ambulatory, independent status, where may become a mechanical issue, thus pain is controlled, and the patient is requesting surgical treatment. Newman PH (1963) The aetiology of of back pain, occupation and physical sis. It remains to be proven whether same spinal pathways that underlie the tendon jerk heightened drive contributes to spinal spasticity reflex. Heparin dosage is regulated by the activated partial throm- Warfarin interacts with many other drugs to cause increased, boplastin time (aPTT), which is sensitive to changes in blood decreased, or unpredictable anticoagulant effects (see Nursing clotting factors, except factor VII. The course of enuresis was as short as one half year and as long as eight years. Because complex motor and • Effective management requires a consistent schedule of intellectual functions require an intact central nervous sys- meals, snacks, blood glucose monitoring, insulin injec- tem, frequent, severe, or prolonged hypoglycemia can be tions and dose adjustments, and exercise. Therefore, these factors may be through modification of gonadal function via in- appear to influence osteoclastic activity through mecha- teractions within the hypothalamus. Play: A student (or patient) experiences the motor skill required to support a spe- cific activity by wearing the glove and playing back the recorded streams that consti- tute the activity. The course of dis- ease was as long as six months and as short as 20 days. That said, I agreed to participate, and the process helped me to develop the program that eventually grew into this book. In end-stage COPD, patients often become steroid- Zileuton is used infrequently because it requires multiple dependent and require daily doses because any attempt to re- daily dosing, may cause hepatotoxicity, and may inhibit the duce dosage or stop the drug results in respiratory distress. Atropine blocks the poison from interacting with the mus- PRINCIPLES OF THERAPY carinic receptor, thus reversing the toxic effects. If so, blockage at the initial the F response is most readily recorded in intrinsic segment may occur more commonly in the smaller, hand and foot muscles, and it has attained special slower conducting motoneurones which are more interest for the investigation of these muscles. You must recognize and accept that every action brings about a reaction, consequences that shape and form our everyday lives. When allopurinol, probenecid, or sulfinpyrazone is given Serum uric acid levels usually decrease to normal range within for hyperuricemia, observe for normal serum uric acid level 1–3 weeks. As described in the previous section, the functional properties of each synapse are deter- mined by four dynamic processes, each having di¤erent time courses. The World Health Organization were accepted for inclusion in the final analysis. It has now been recognised that healthy subjects and are to investigate to obtain the best current evidence with respect pharmacodynamics, pharmacokinetics to a particular therapy, all pertinent clinical trial and toxicity. Knee Flexion upon loading Healthy elderly people walk more slowly and Extension at mid stance have a shorter stride length than young adults. What are adverse effects of commonly used antidiarrheal (after every bowel movement). Weakness of the connections between some close synergists acting at the same joint Widespread transjoint connections and walking In the cat heteronymous monosynaptic Ia facilita- tion is strong between close synergists operating Transjoint heteronymous Ia connections are almost at the same joint, e.
8 of 10 - Review by G. Asam
Votes: 212 votes
Total customer reviews: 212


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Read this tip to make your life smarter, better, faster and wiser. LifeTips is the place to go when you need to know about Kitchen Beautician and other Beautify topics.
Shampoo hair and towel dry. Mix together 1/2 cup plain yogurt, 1 egg yolk and 1 Tblsp honey. Rub into hair, cover with shower cap and leave on for 20 min. Rinse, then shampoo thoroughly.
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|Byron White

subset: commoncrawl


text: Okay, if I ramble, I'm sorry. We have 7 hens (all diff breeds, you can see in my signature thing). They are all about 24 weeks. First, the eggs. I got my first egg on Monday. Since then, it's been 2-3 per day. All of the eggs have been behind the nest boxes with the nest boxes untouched with the golf balls inside No biggie, getting eggs is just about the coolest things ever I might add. I have some fake brown eggs that are being shipped so maybe that might help. The girls have always gone in the coop on their own. I decided to put in a poop board. It took a night or two but then they all came in, no problem. A week or so later I hung a heat lamp. I didn't turn it on, just put it in. Since then, 2 consistently, sometimes up to 4 don't come in the coop, they sleep in the run. My hubby thought maybe there wasn't enough room between the door in the floor and the poop board since they are getting bigger. The 2 that are consistently down are the orpington and brahma, both big girls. So, I removed the poop board and got a couple of more private nest boxes in anticipation to some egg laying. It looks perfect to me. Now, tonight 4 are down below. It's supposed to snow here tomorrow and I don't know what to do. I've put them in a couple of times but it kills me to bend in there and crawl around in poop, etc... So, will they eventually go in if they get too cold? Should I just be consistent and catch them all and make them go up until.....forever? The run is skirted with haybales so where they sleep is blocked by those. Hubby thinks maybe I should move them so the only "safe" feeling place is the coop. If you made it this far...Thanks!!


text: John Liu/Flickr Planet Money Episode 573: Why Textbook Prices Keep Climbing October 3, 2014 Prices of new textbooks have been going up like crazy — faster than food, cars, even healthcare. On today's show: why textbooks have gotten so expensive. Episode 573: Why Textbook Prices Keep Climbing Listen · 14:56 14:56 Toggle more options Download Embed Embed <iframe src="https://www.npr.org/player/embed/353300404/353568847" width="100%" height="290" frameborder="0" scrolling="no" title="NPR embedded audio player">


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The third and final debate of presidential candidates Al Gore and George W. Bush was the best of the three -- in large part because it reinforced what these exercises are all about. And that is, how do the two candidates differ in terms of specific plans for the nation beginning in January 2001.
The two candidates do indeed differ: Gore has in mind a Washington-type, experienced-in-federal-government leadership; Bush an outsider, less-federal-government-oriented approach.
In questions dealing with issues ranging from health-maintenance organizations to national health insurance to Medicare, Social Security, tax cuts, farm programs and capital punishment, the two candidates expressed their differences. Except for capital punishment, in which they shared a consensus, their differences were clear and obvious to viewers, who should be more informed about their choice on Nov. 7.


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Most counts of contempt in Minn. terror case nixedAppeals court throws out 19 of 20 contempt counts against Minn. woman convicted in terror case
MINNEAPOLIS (AP) ' A federal appeals court has thrown out 19 of 20 contempt-of-court citations against a Minnesota woman convicted of funneling money to terrorists in Somalia.
The Eighth U.S. Circuit Court of Appeals on Monday affirmed the first contempt charge against Amina Farah Ali, a Muslim, who refused to stand for the judge and jury early on in her trial last October, saying it is prohibited by her religion. The three-judge panel vacated all other contempt counts against Ali and sent the case back to Chief U.S. District Judge Michael Davis.
The appeals court says the judge ruled only on First Amendment grounds, and failed to consider a separate federal law protecting religious freedom.
Ali and a co-defendant, who say they only sent money for the poor, await sentencing on terrorism-related charges.
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Related Keywords:Terrorism-US-Somalia,Terrorism,National courts,War and unrest,General news,National governments,Government and politics,Courts,Judiciary


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Office Staff Deputy Director Mr. Du Baishun +86-913-2133927 firstname.lastname@example.com Staff Member Ms Wang Weiwei +86-913-2133927 firstname.lastname@example.com
Business Hours Monday-Friday 08:00am—12:00am 14:00pm—18:00pm
How to get to WNNU By train It takes about 45 minutes to travel by train from Xi'an to Weinan, then take a taxi or bus to WNNU. The cost ranges from 4.5 to 39 RMB. By airport coach You can take the airport coach from the Xianyang International Airport arrival terminal to the center of Xi'an. The ticket is about 25 RMB. Then take a bus to Weinan for about 17.5 RMB.You can also take an airport minibus from the Xianyang International Airport arrival terminal to the Weinan Train Station. The cost is 40 RMB and the bus leaves every few hours from 6am-8pm.
Mailing Address Department of International Cooperation & Exchanges Weinan Teachers University West Chaoyang Street, Weinan, Shaanxi, P.R., China, 714000


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Telelink Plc
Member Since: 2006
Building 12A, Floor 3
1715 Sofia
359 2 970 40 40
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AFCEA Contact:
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Long gone is the fact that the whole thing is made up by a manipulative and hateful ex-wife who wants to get back at him for things he did, or was perceived to have done, that pissed off the ex wife.
Look at that teacher who caught those little girls in a sex act. The little girls reported the TEACHER for touching them and she spent her life savings, and in the mean time her reputation was ruined, to try to defend herself. She was found not guilty and there are still people that want her head on a pole thinking she touched those girls. Come to find out the girls were touching each other, and when caught, turned on the teacher that caught them.
That wonderful woman will never teach again as her reputation is ruined, she'll always be "that teacher accused of touching those little girls." Just the ACCUSATION is enough to ruin someones reputation. That's what people just don't realize.


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The following incidents occurred on Wednesday, August 9th, 2017:
Warrant Arrest:
At 3:39 PM, Ashley R. Hauser, 27, of Monroe, turned herself in at the Green County Sheriff's Office for a warrant that was issued by Wisconsin Department of Corrections. Hauser was jailed.
Motor Vehicle Crash-Personal Injury:
At 6:23 PM, Deputies, along with Belleville Police, Belleville EMS, and Belleville First Response responded to the N9000 block of
STH 92, Town of Exeter, for a two-vehicle crash with injuries.
Investigation revealed that Tonia J. Chapman, 34, of Belleville, was traveling south on STH 92 and was slowing down for a vehicle that was turning when she was rear-ended by a vehicle that was operated by Daniel W. Meier, 18, of Belleville.
Chapman was wearing her seat belt and the air bags did not deploy in her vehicle. Chapman was injured in the crash and was transported by EMS to a local hospital. The vehicle sustained moderate damage and was driven from the scene.
Meier was injured in the crash, but declined medical attention. Meier was wearing his seat belt. There was air bag deployment in the vehicle. The vehicle sustained severe damage and was towed from the scene. Meier was cited for Unreasonable and Imprudent Speed and released pending court.
Motor Vehicle Crash:
At 7:07 PM, Deputies responded to a one-vehicle crash in the W700 block of STH 11, Town of Spring Grove. Investigation revealed that Kyle B. Steiner, 27, of Brodhead, was eastbound on STH 11 when he fell asleep. Steiner's truck then entered the ditch and struck a road sign. Steiner was not injured and was wearing his seat belt. The air bags did not deploy in the truck. The truck sustained moderate damage and was driven from the scene. Steiner was cited for Failure to Maintain Control and was released pending court.
At 8:04 PM, Deputies responded to the N9100 block of CTH O, Town of New Glarus, for a one-vehicle crash. Investigation revealed that Cade K. Hellenbrand, 18, of New Glarus, was traveling north on CTH O when he lost control of his vehicle and entered the ditch. Hellenbrand then struck a traffic sign and power pole.
Hellenbrand advised he was not injured and was wearing his seatbelt. The air bags deployed in the vehicle. The vehicle sustained severe damage and was towed from the scene. Hellenbrand was cited for Failure to Maintain Control and was released pending court. The New Glarus Police Department assisted at the scene.
Disorderly Conduct:
At 9:40 PM, Deputies, along with the Brodhead Police Department, responded to the N3200 block of Crazy Horse Lane, Town of Decatur, for a Disorderly Conduct case. The investigation resulted in Clayton S. Welte, 21, of Brodhead, being arrested for Disorderly Conduct and 2 counts of Felony Bail Jumping. Welte was jailed pending court.
Motor Vehicle Crash - Car vs. Deer:
Sonya A. Johnson - N9200 block of STH 104, Town of Brooklyn
Patrol Sergeant Bernie Roidt #8
Green County Sheriff's Office


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This spring Suzan Windnagel, past Caz Board member and long-time Caz fan, made a very generous endowment gift to the Travis Davison Scholarship Fund. The fund was established in 2007 in memory of Travis Davison, Suzan's late husband, who was a Caz alumnus and passionate Caz advocate throughout his life. The fund will provide three or more scholarships per year, in perpetuity, for young trombonists with financial need. We spoke with Suzan earlier this month about her experience with Caz and her decision to make this generous gift.
When did you first come in contact with Cazadero?
The first time I heard about Caz was when I met Travis in 1995 at an executive training program in Madison, Wisconsin. We both worked for financial institutions and were there to learn more about banking, but Travis just wanted to talk about how Caz was restarting, and that he was so excited he could hardly stand it!
My first visit to Caz was in 1996. The spot was so beautiful, and while the place was pretty dilapidated, you could really visualize what was going to happen. The summer of 1997 was the first time I saw campers there, and I was completely blown away. There was so much energy, the music wastrav bouncing off the trees, and there was a vivid excitement in the air aboutrestarting the camp.
Trav was a member of the new Board, I believe he was the Treasurer, and later he became the President. I didn't come on the Board until 1998. Trav and I shared a board seat, which was a situation unique to Caz!
What do you think makes Caz special?
One of the things that really struck me initially was hearing the stories about the old Caz, while watching the new Caz develop. I was struck by the lasting relationships that develop at Caz, and the real sense of belonging that exists there. From the CITs to the Kitchen staff to everyone else there is a sense that everyone belongs and that they are all creating the Caz experience together. It's really special.
The other thing that makes Caz different is this sense of history. It was created by the Lutts and a handful of people, but it lives on, and there is this ongoing desire to share this experience with others, to connect people through music. It's like passing on a gift from one person to the next.
In the bigger picture, there?s a conscious effort and careful planning throughout the whole organization - what is it that will make this two week camp a life changing experience for kids? It's a place for music, for building confidence, for building friendships, and it?s all woven together, like a tapestry, interdependent and strong.
Why did you decide to start a scholarship endowment in honor of your late husband, Trav Davison?
When Trav and I brought our two lives together, we decided what was important to us. Caz was in our top five - we knew we'd support it with our time as well as financially. Caz had meant so much to Trav's life, it had really touched who he was, from age 11 on. He developed his musical confidence there, his leadership ability, and deep friendships that lasted to the end of his life.
Trav really believed in the mission of Caz. He felt such care and attention from the people at Caz, starting with Bob & Beth Lutt. As a camper, the staff had supported him experimenting with a new instrument, and encouraged his potential for leadership, first as a CIT, then as a Counselor. And somehow it meant more at Caz, knowing how strong the competition was for those jobs.
Trav met people at age 11 who were there for him when he died at 58. He had this cadre of people who had shared something special together at Caz, and who took care of one another. They helped Trav play music near the end of his life when it became difficult for him to make music, for example. He ended up playing music and singing until just before he died. And Caz was huge part of that.
Recently, watching my niece, Kate Windnagel, experience Caz as a camper helped me decide to fund the endowment at a higher level than initially planned. I could vividly see what Caz meant to a young person, how it impacted her life on a day-to-day basis once she returned home, how the friendships are lasting. So it's as much about her development as a young adult as it is about her musicianship. I want that opportunity offered to other young people. It should be for kids who are a good match for Caz, and vice versa, regardless of socio-economic background. It's gratifying to help make that happen.
Last, Trav and I trust Caz to make a difference....trust in the leadership of the board and the administration to use the endowment funds to help kids and Caz be successful now and in the future.
Why do you think it?s important to support music education today?
Knowing what I know now about the creative arts and what it does for people, when we look at our entire lives, it's the creative arts that help make us human, and the some of the most joyful expression is made through music. If we don't sing to one another, play instruments, do rhythmic kinds of things as children, our lives will not be as rich, and even more so as we age. If music education isn't there for kids, then we lose some of our humanity, and some of who we are as people.
Why are programs like Caz important?
I think the Caz experience is especially important for kids now. Their lives are so full - they are running from here to there, and in a way, their lives seem disjointed. But when you come to Caz, it consolidates their experience, they get to reflect on who and what they are. That opportunity to be away from cell phones and technology gives them a chance to delve into things in a deeper way. The other thing is that they get to experience being out of their comfort zone. It's a very positive way to try something new.
Any other thoughts you?d like to share?
I'm so gratified and pleased that Caz continues on. I'm so happy that two of my nieces have had such a fabulous time at Caz. I can't imagine there not being a place like Caz for kids today. We all need to do what we can to keep Caz thriving.


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April 19, 2011
Tonight was our first t-ball game of our first season. The team did a really good job and came out with a first win! Yay! It was so much fun watching them play and watching the Dads interact with each of them. When the ball is hit they all come running to get it. (Even if it involves some hits and tumbles like football!) It is going to be a great season of baseball and friends. It is amazing that there is standing room only at the t-ball field! Lots of proud Mommies, Daddies, Grandparents, Aunts, Uncles, Cousins, and Friends!
|Win! and we didn't get to bat for the last time!


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Wednesday, December 28, 2011
lyrics against Kanye's "Big Brother", Jay-z. But the bigget, and I mean BIGGEST issue about Lil Wayne was, "WHAT THE HECK IS DUDE WEARIN ON HIS FEET???" JUNKS LOOK LIKE MOON SHOES!!!! LOL! But after researching the shoes/boots they are made as a collaberation between Vans and a brand called Celtek and they're basicly Snowboarding boots. Not for nothin,even though they look a little awkward, wayne is kinda killin these joints. And I can also see these catching on in mass appeal. Specially with the cats who are trying to merge the line between hood gangster rapper, skater, and rockstar. Over the years lil wayne hasn"t been one of myfavorite style stars. Basicly because he never really had a definitive style. But one thing you can't take away from him is he does what he feels. He alwys finds a way to make noise and cause controversey with what he has on. Like in September when he rocked the leopard jeggings to the mtv awards. very bold and ballsy move for a gangster rapper. I mean Snowboardingboots aren't anything New. Two years ago Pharrell Rocked a pair of Nike Snowboarding Boots to Paris fashion week and people chalked it up to that being Pharrell. I guess as star the critics are always gonna come at what you waer. But in the end, as a star it's about selling yourself ad causing controversy. And through what he's been wearing, wayne has been doing just that. He also caused an erruption on the net when he wore lime green ugg-type snow boots in drake's video for the motto!!! Well lets wait and see what wayne comes up with in the upcoming year.
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We determined that the single-ear headset was the perfect solution for the sports bar environment since it allows you to converse with others while hearing your favorite event.
Thousand Oaks, CA (PRWEB) October 14, 2009
One of the biggest dilemmas that sports bar managers face is deciding what game to broadcast and whether to broadcast the sound through an overhead speaker system or directly from the TV itself. With many facilities playing 15 or more events, deciding which game appeals to the greatest number of patrons can be a challenge and the simultaneous sound from multiple games and TVs creates major noise pollution and can be very uncomfortable for guests.
One company, Broadcastvision Entertainment (http://www.broadcastvision.com) who pioneered a similar solution for fitness centers many years ago, has come up with a very affordable and effective solution for the legendary Ocean View Inn and Sports Pub of Islamorada in the Florida Keys (http://www.theocean-view.com).
Broadcastvision, a leading manufacturer of wireless transmitters and receivers for health clubs, fitness centers, sports bars, and correctional facilities worldwide has recently installed its new digital FM single ear headset system at the Ocean View Inn and Sports Pub, a sports bar owned by former Pittsburgh Steelers, Gary Dunn. Ocean View was the first pub to be issued a liquor license in the Florida Keys!
In early summer 2009, Ocean View general manager Larz Tatro contacted Kevin Fee, director of business development at Broadcastvision, to find a solution that will allow patrons to privately listen to the many sporting events being played on the pubs' high definition televisions within the bar and outside patio areas. "I had seen a Broadcastvision wireless system at one of the fitness centers in the area and contacted them about what innovative solutions they might have for a sports bar environment." says Tatro.
A new FM wireless system released this summer by Broadcastvision, wirelessly transmits the TV audio on vacant FM frequencies, allowing bar patrons to listen to any of the sporting events on a small digital single-ear headset radio. Patrons can easily adjust the volume or change games on the earpiece. "We determined that the single-ear headset was the perfect solution for the sports bar environment since it allows you to converse with others while hearing your favorite event." says Fee.
A popular benefit of the single-ear FM headset is that it can be branded with any company or sponsorship logo. The headsets are also inexpensive enough to resell or gift to patrons for promotional purposes.
In addition to large screen LCD TVs and brackets, music/messaging and sound systems, Broadcastvision also manufactures wireless 900MHz transmitters, receivers and personal viewing screens for military fitness centers, multi-unit housing properties, universities and medical environments.
Kevin Fee
Broadcastvision Entertainment


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Zoey is the perfect cupid, but that Sadie is a hard nut to crack, so to speak. Romance may not be happening, much to Howie's distress!ReplyDelete
Oh...how darling. It'll work. Howard just needs to give it some time. Sadie's bound to crack within the next 5 years or so...ReplyDelete
Maybe my favorite part of this is knowing you and Tim were wetting yourselves laughing while making this. However, it is quite awesome.ReplyDelete
HOW ADORABLE!!! :)ReplyDelete


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POLICE are hunting thieves who robbed a Securicor guard and made off on a stolen Asprilla scooter.
The pair struck around 3.20pm on Saturday just after the 44-year-old guard collected cash from premises at the Longfield Shopping Centre on Bury New Road in Prestwich.
They took a green coloured cash box holding an unknown amount of money. The men headed off along on a blue Asprilla scooter - registration number: Y603 SNC - along Bury New Road in the direction of Salford.
The bike, which had been stolen on July 19, was later found abandoned on a dirt track near Butterstile Lane in Prestwich.
Police say a security device had been activated which would cover the cash box and its contents with red dye. Any witnesses should call: 856 8212.


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Hariane Côco1,2* and Ana Maria de Oliveira2
1Departamento de Farmacologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (USP), Avenida do Café s/n, Brazil
2Laboratório de Injúria Vascular, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, USP; Avenida do Café s/n, Monte Alegre, Brazil
Received date: November 18, 2015; Accepted date: December 11, 2015; Published date: December 17, 2015
Citation: Côco H, Oliveira AM (2015) Endothelial Dysfunction Induced by Chronic Psychological Stress: A Risk Factor for Atherosclerosis. Cardiovasc Pharm Open Access 4:168. doi:10.4172/2329-6607.1000168
Copyright: © 2015 Côco H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Visit for more related articles at Cardiovascular Pharmacology: Open Access
The exposure to psychological stress can increase the risk of cardiovascular disease due to impaired endothelial function. Mediators such as glucocorticoids, catecholamines, angiotensin II and/or pro-inflammatory cytokines, induced by stress, can contribute to endothelial dysfunction due to increased levels of oxidative stress. The endothelial dysfunction induces reduced expression and/or endothelial nitric oxide synthase enzyme functionality, as well as the impairment of the actions triggered by its metabolite, nitric oxide. Chronic psychological stress leads to atherosclerosis development, which has an endothelial dysfunction at early stages. The oxidative damage and inflammatory mediators, induced by chronic psychological stress, play a key role in this process. Furthermore, chronic psychological stress can contribute to the formation of unstable atherosclerotic lesions as a result of immune system cells accumulation and molecules adhesion, leading to thrombosis and cardiac complications. According to what was stated above, we aim to discuss about the endothelial function impairment mediated by psychological stress, and the involvement of mediators such as glucocorticoids, catecholamines, angiotensin II and pro-inflammatory cytokines in this response. This review covers current advancements to understand how chronic psychological stress could lead to atherosclerosis development.
Chronic psychological stress; Oxidative stress; Inflammatory factors; Endothelial dysfunction; Atherosclerosis
Chronic exposure to stressful situations is associated with increased risk of cardiovascular diseases [1], including acute myocardial infarction [2], coronary artery disease [3-5], myocardial ischemia [6] and atherosclerosis [7,8]. The odds for acute myocardial infarction have increased more than twice in individuals who were exposed to psychosocial factors associated with exposure to multiple risk factors, such as hypertension, smoking, diabetes mellitus and obesity, in comparison to those who were not exposed to psychosocial factors [2]. The increased risk to acute myocardial infarction triggered by exposure to psychosocial factors was independent of gender, age or geographic distribution [2]. The greatest severity of stress-triggered depressive symptoms was related to reduce long-term survival after myocardial infarction [9]. It has been studied the relation between panic disorder, considered as part of the multifactorial clinical picture of mental stress, and coronary artery disease [10]. Soares-Filho et al. [11] discussed about the endothelial dysfunction and microvascular disease present in mental stress response and suggest that mechanisms from the perspective of endothelial dysfunction and microvascular disease might be involved in mental stress. All these findings suggest that the pathophysiologic effects of psychological stress may trigger the development of cardiac events.
Stress is a state of disharmony or threat to homeostasis, caused by psychological, environmental or physiological stressors, which lead to specific or generalized adaptive responses [12]. The biological systems respond to stressful stimuli and attempt to develop an adaptation process to these alterations induced by stressors [13]. An imbalance between stressors and response against it leads to maladaptation, which can be a promoter of various diseases, including cardiovascular diseases [13].
The responses to stressors are initiated by the sensory system stimulation, leading to the activation of several adaptive mechanisms, such as hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system [14]. Mental stress stimulates the paraventricular nucleus of the hypothalamus, where corticotropin-releasing factor is produced and released, which acts on pituitary in order to release the adrenocorticotropin hormone, resulting in the releasing of glucocorticoids from the adrenal glands cortex [15]. Increased serum levels of glucocorticoids can lead to biological alterations in the body, including the development of some psychological disorders and systemic diseases, such as inflammatory, metabolic and autoimmune diseases [16-19]. Abnormalities in HPA axis functionality have been associated with cardiovascular risk factors [20,21]. Additionally, the sympathetic nervous system activation triggers increased vascular tone, myocardial oxygen consumption, platelets activation, as well as activation of renin-angiotensin system, which results in endothelial dysfunction, and hence, the development of cardiovascular diseases [13].
Endothelial dysfunction is mediated by impaired nitric oxide (NO). The endothelium-derived NO plays a main role in maintaining vascular homeostasis, and it is an important mediator of vasodilation. The biosynthesis of NO results from the oxidation from L-arginine to L-citrulline, catalyzed by the nitric oxide synthase enzyme (NOS), in presence of tetrahydrobiopterin cofactor (BH4). There are three isoforms of NOS, one induced by immunological stimuli (iNOS) and two of them constitutive, endothelial NOS (eNOS) and neuronal NOS (nNOS) [22]. After it is produced, NO diffuses from the endothelium into the vascular smooth muscle and lead to vascular relaxation. This fact occurs because NO binds to the soluble guanylyl cyclase heme (sGC) enzyme and produces cyclic guanosine monophosphate (cGMP), which activates protein kinase (PK) G, triggering a cellular signaling cascade, which decreases the concentration of cytosolic calcium, and hence, the vascular relaxation [23].
Considering the importance of NO on vascular homeostasis regulation, an imbalance between reduced NO bioavailability and/ or increased endothelium-derived contractile factor could lead to endothelial dysfunction [24]. The lower NO bioavailability can result from the consumption of NO by reactive oxygen species (ROS), reduced eNOS expression [25] and lack of eNOS substrate or cofactors [26]. The latter plays an important role in the enzymatic decoupling, resulting in ROS production instead of NO.
Oxidative stress is defined as an imbalance between antioxidant defenses, such as superoxide dismutase (SOD) and catalase, and ROS, such as superoxide anion (O2-) and hydrogen peroxide (H2O2) [27]. Many enzymatic systems can produce O2 -, as decoupled NOS [28], cyclooxygenase (COX) [29] and nicotinamide-adenine-dinucleotidephosphate enzymatic complex (NADPH oxidase). The latter is the biggest source of ROS in vascular cells [30,31].
Recent studies suggest that psychological stress triggers endothelial dysfunction [32]. Patients with mild symptoms of depression or stress, showed high depression or stress score associated to reduced brachial artery flow-mediated dilation, which suggests the relationship between stress and endothelial dysfunction [33]. Mice exposed to chronic unpredictable stress, for 8 weeks, showed impaired endotheliumdependent relaxation in aorta [34]. The relaxation response, induced by acetylcholine (ACh), was also significantly reduced in thoracic aortas from rats exposed to chronic unpredictable stress for 3 weeks [35]. These results suggest reduced production and/or bioavailability of NO after stress. Additionally, chronic unpredictable stress increased the potency of phenylephrine (PE) in thoracic aortic rings from rats, suggesting that the possible lack of NO bioavailability could contribute to hyper reactivity of agonists and impair the vascular function [35,36].
According to the previously described findings, the acute restraint stress reduced vascular and plasma levels of NO metabolites, nitrate and nitrite, and increased O2 - levels in rats' aorta, suggesting endothelial dysfunction as a result of oxidative stress, induced by stressful situations [37]. Acute restraint stress also increased the reactivity to PE in rats' aorta, and pre-incubation with L-NAME non-selective NOS inhibitor did not affect this response, suggesting that increased contraction induced PE in aorta from stressed rats may be due to impaired modulation of NO [37].
The mechanism in which stress induces endothelial dysfunction may involve important mediators, including glucocorticoids, catecholamines, angiotensin (Ang) II and pro-inflammatory cytokines. Treatment with antagonists of glucocorticoid receptors, mifepristone, improved the endothelium-dependent relaxation and the eNOS gene expression in mice's aorta, both impaired by chronic stress [38]. Mifrepristone also reduced ROS vascular levels, which were higher after stress. These findings suggest that glucocorticoid generation, induced by exposure to stress, impair endothelial function [38]. The exposure to dual challenge (physical and psychological stress) increased the levels of noradrenaline and oxidative stress, as well as the noradrenaline areaunder- the-curve was positively correlated with peak oxidative stress marker 8-isoprostane, suggesting that the increased noradrenaline levels may be involved with increased oxidative stress after physical and psychological stress. This fact could contribute to endothelial dysfunction [39].
The increased sympathetic activity, induced by stress, contributes to the activation of the renin-angiotensin system [40,13]. Stress-induced sympathetic activation of beta-adrenergic receptors in the kidneys increases renin formation and subsequently, the generation and release of Ang II into circulation [41]. Plasma renin activity and/or Ang II levels are increased in subjects exposed to situations of fear, novelty [42] and to hot temperatures [43]. In rats, the activation of renin-angiotensin system also increased in response to chronic restraint stress [44,45]. Chies et al. [46] demonstrated that rats exposed to swimming stress presented reduction in the contractile response induced by Ang II in thoracic aortas and mesenteric arteries, suggesting that the exposure to stress alters the vascular reactivity to Ang II.
The increase in Ang II levels, induced by psychological stress, influences endothelial function. The chronic restraint stress reduced endothelium-dependent relaxation, plasma levels of stable NO metabolite (nitrate and nitrite) and vascular eNOS gene expression, as well as increased oxidative stress [45]. The treatment with AT1 receptors antagonist, losartan, or angiotensin-converting enzyme inhibitor, ramipril, blunted these responses, suggesting that the involvement of AT1 receptors and Ang II in the endothelial dysfunction, induced by chronic restraint stress [45].
The inflammatory process can also trigger endothelial dysfunction. Treatment with etanercept, an anti-TNF-α, improved the endotheliumdependent relaxation and the eNOS protein expression, both impaired in aorta from rats, after exposure to chronic unpredictable stress [47]. These results show that TNF-α plays an important pathophysiological role in the endothelial dysfunction induced by stress.
Thus, abnormalities in functionality of HPA axis or increased sympathetic activity, and hence, increased levels of glucocorticoids and catecholamines, lead to higher levels of oxidative stress and inflammation, which are considered risk factors for endothelial dysfunction. Consequently, these factors may increase the risk of cardiovascular diseases development, including atherosclerosis [48].
Atherosclerosis is a chronic disease characterized by formation of atheroma in the medium and large artery wall. The development and progression of atherosclerotic lesions are triggered by endothelial dysfunction, followed by recruitment of leukocytes to the vascular wall, which modifies the structure of low density lipoproteins (LDL) deposited on the endothelial layer. Among the LDL modification, the oxidation induced by ROS results in formation of oxidized LDL and hence, these modified LDL suffer phagocytosis by macrophages and accumulate in vascular cells. These alterations lead to formation of foam cells, which can initiate atherosclerotic lesions [49].
The development of atherosclerosis associated with psychological stress has been studied since 1983. Chronic psychosocial stress increased area occupied by intimal lesion in monkeys' coronary artery, in the absence of other risk factors for atherosclerosis, such as alterations in lipid levels, blood pressure or glucose. These findings suggest that psychosocial stress causes atherosclerotic lesions in nonhuman primates without any traditional risk factor [7].
The impaired endothelial function induced by stress triggers pro-atherogenic effects. Concentration-effect curves showed greater PE potency in endothelium-intact aorta from rats, after exposure to chronic unpredictable stress [36]. The pre-incubation with NOS inhibitor, L-NAME, did not alter this response, suggesting that, the increased PE potency induced by stress can be related to decreased production and/or bioavailability of endothelial NO [36]. These alterations were associated with an increase in the total intima-mediathickness of the carotid artery [36], a parameter that indicates a risk factor for cardiovascular disease [50].
Chronic restraint stress has increased the levels of oxidative stress in aortas from apolipoprotein (Apo) E-deficient mice, resulting in increased expression of LOX-1, a receptor to the modified LDL [51]. Treatment with EUK-8, a mimetic of SOD and catalase enzymes, reversed the increased LOX-1 expression, suggesting that chronic restraint stress upregulates vascular LOX-1 expression, through a mechanism that involves increased oxygen free radicals generation, which may contribute to the development of pro-atherosclerotic conditions [51]. In addition, mice exposure to chronic restraint stress increased oxidative stress levels in the liver, kidney and heart, and this response was associated with reduced activity of liver antioxidant enzymes [52]. These changes were accompanied by the formation of foam cells and accumulation of lipids in the mice's aorta, suggesting that chronic stress leads to oxidative stress and also to initiate atherosclerotic lesions [52].
Atherosclerotic lesions are characterized by sub-endothelial retention of inflammatory cells, whose adhesion is mediated by adhesion molecules, such as vascular (VCAM-1) and intercellular cell adhesion molecules (ICAM-1). On the other hand, the leukocyte migration is induced by chemokine expression in the vascular wall, such as monocyte chemotactic protein (MCP-1). The pro-inflammatory cytokines, including TNF-α, interleukin (IL) -1 and IL-6, secreted by activate inflammatory cells, maintain an inflammatory vascular environment and thus, perpetuate atherosclerosis [53].
Chronic stress plays a critical role in the induction of vascular inflammation and progression of atherosclerotic lesions [54-57]. The chronic unpredictable stress increased plasma TNF-α levels and its expression in rabbits' aorta, as well as infiltration of macrophage and lipid accumulation in the sub-endothelial space. Such characteristics are similar to initial stages of atherosclerosis [57]. Vascular smooth muscle cells treated with serum from stressed rabbits showed increase in the expression of MCP-1, ICAM-1, phosphorylation of mitogenactivated protein kinase (MAPKs), MAPKp38 and c-jun N-terminal kinase (JNK) [57]. The MAPKs signaling pathway regulates the processes of cell differentiation and proliferation, protein expression to leukocyte adhesion and it is involved in the atherosclerotic process. Pro-inflammatory effects induced by chronic stress were partially blocked by anti-TNF-α antibody, MAPKp38 and JNK inhibitors, suggesting that TNF-α, MAPKp38 and JNK activation can play a critical role in the pro-inflammatory and pro-atherogenic effects after chronic stress [57].
The rupture of atherosclerotic plaque is considered one of the main causes of cardiovascular complications [53]. A plate with large lipids pool, a thin fibrous cap and many inflammatory cells is prone to suffer rupture when an external stimulus occurs, such as psychological stress. Chronic unpredictable stress led to a plaque rupture and increased plaque size in brachiocephalic arteries from Apo E-deficient mice, as well as accumulation of inflammatory cells and adhesion molecule in the atherosclerotic lesions. These data suggest that the alterations, mediated by chronic stress on plate composition, can promote instability and contribute to its rupture [54].
The participation of adrenergic receptors in the inflammation, induced by stress-associated atherosclerosis, has been studied. Apo E-deficient mice exposed to social disruption stress showed a correlation between stress-score and median aortic plaque area, as well as increased levels of IL-6 pro-inflammatory cytokine. These observations suggest that psychological stress is involved with the atherosclerosis progression, and the release of IL-6 may be a potential mechanism for the atherosclerosis development [56]. The selective beta1-adrenoceptor blockade with metoprolol prevented the increased IL-6 levels in plasma, induced by social disruption stress, suggesting that the sympathetic nervous system may mediate the release of IL-6 and lead to a progression of atherosclerotic lesions [56]. The inhibition of alfa/beta-adrenergic receptors reduced the lipid deposits, induced by chronic restraint stress, in aortas from Apo E-deficient mice, suggesting that the stress-induced atherosclerotic lesions are associated with activation of adrenergic receptors [58].
Increased activity of the sympathetic nervous system reduced the CXCL12 chemokine expression in the bone marrow from mice, after exposure to chronic unpredictable stress [59]. One of the main functions of this chemokine is to inhibit the migration and proliferation of hematopoietic stem cell, and hold the neutrophils inside the bone marrow. Thus, the reduced expression of CXCL12 led to proliferation of hematopoietic stem cells, and increased production of neutrophils and monocytes. These events resulted in increased release of inflammatory leukocytes into circulation, and hence, the development of inflammatory plaque [59]. The treatment of stressed mice with beta3-selective receptor antagonist, SR 59230A, has limited the progression of atherosclerotic lesions, which supports the idea that the sympathetic nervous system, signaling via beta 3-adrenergic receptors activation, has targeted the CXCL12 chemokine in the bone marrow, and it could be explored as potential therapeutic approach in the stress-induced atherosclerosis [59].
Psychological stress activates the sympathetic nervous system, renin-angiotensin system and the HPA axis, triggering increased levels of catecholamines, glucocorticoids and Ang II, respectively. All these mediators can promote endothelial dysfunction due to the increase in oxidative stress and circulating inflammatory mediators, as well as reduced NO production or bioavailability. These alterations lead to vascular inflammation and, consequently, the development of atherosclerosis. Furthermore, TNF-alpha and MAP kinases signaling pathway played a potential role in the inflammatory process, as well as the adrenergic receptors and CXCL12 chemokine that are involved with hematopoietic activation and the development of atherosclerotic lesions.


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Cuddles Cottage Boarding Cattery, Boarding Kennels - Dogs, listed under "Boarding Kennels - Dogs" category, is located at 9 Nardoo Pl Beechwood NSW, 2446, Australia and can be reached by 0265856888 phone number. Cuddles Cottage Boarding Cattery has currently 0 reviews.This business profile is not yet claimed, and if you are the owner, claim your business profile for free. If you are not the owner you can invite this business to join by email or by phone.Browse all Boarding Kennels - Dogs in Beechwood NSW.
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Any recommendations that aren't too spendy?
Any recommendations that aren't too spendy?
in a van, DOWN BY THE RIVER.
sorry, couldn't help myself
27' Wooldridge Super Sport Offshore Pilothouse PRIME TIME!
Kodiak Custom Fishing Tackle Pro Staff
Heavy Hitter Fishing Crew
Define not too spendy. How many people will you need to accommodate?
I took Brian M's advice from the forum a while back and have loved this place he recommended. You can have up to five people and can't beat the view.
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Virgil, Are you going to be here August 2nd-4th?
if you decide a hotel is the option for you. i would recommend Lands End on the spit only. Working at the police dept i learn more than i want to.
there are a ton of cabins and such in homer and for the hunter, id expect you would be happier there than hotel
If you stay at lands end you can pretty much walk anywhere you need to on the spit. Lands end is not the cheapest, and the restaurant is a restaurant by virtue of the view, not the cuisine.
There are some decent places to stay above the little mermaid restaurant (best on the spit) the sport shed, and the sea lion gallery.
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Alaska Board of Game 2015 tour... "Kicking the can down the road"
oh i forgot about all the cabins over the fishing charters. great views and centrally located too.
i'd just grab a taxi if you need to go into town. there is a rental place in town if need be tho. Finn's pizza is a must while your here
I really enjoy camping on the spit. It's bare bones, but everything is available. Meet lots of fun people, be right at the fishing hole, and docks. Walk to the hotel, or the Salty Dog. If it's nasty then I get a room in town.
Here's a nightly rental I did some work on recently....built the four-poster beds, and did a little remodeling....it definitely ain't cheap but it sure is nice : http://www.vrbo.com/485919
" Gas boats are bad enough, autos are an invention of the devil, and airplanes are worse." ~Allen Hasselborg
We used to stay in the Windjammer suites. Nice little place on pioneer, so it's walking distance from a bunch of little cafés, restaurants, books store, liquor store, etc. great price. Not the prettiest but very livable. Highly recommend.
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I stayed at the best western a couple weeks ago with my family and two dog. No complaints at all, good bar/restaurant, Wifi, great free breakfast. One downfall could be that it is not within walking distance of the spit.


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tag:blogger.com,1999:blog-60352699527012838182018-03-05T10:42:44.852-08:00Go Geezers Guide: Theater in Portland4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-49949596881543889512013-07-01T23:27:00.001-07:002013-07-01T23:27:15.959-07:00Bloody Bloody Andrew Jackson - Portland PlayhouseBook by Alex Timbers Music & Lyrics by Michael Friedman
Directed by Brian Weaver
Storyteller - Lorraine Bahr
Andrew Jackson - Logan Benedict
Adams/Ensemble - Sean McGrath
Tour Guide/Ensemble -Cristi Miles
Black Fox/Ensemble - Jared Miller
Clay-Ensemble - Chris Murray
Rachel - Melissa Murray
Monroe/Ensemble - Darius Pierce
Ensemble - Danielle Purdy; Alexandra Ramirez
Van Buren/Ensemble - Jason Rouse
Announcer/Ensemble - Jennifer Rowe
Cheerleader/Ensemble - Beth Thompson
Naomi/Ensemble - Sara Catherine Wheatley
Calhoun/Ensemble - John San Nicolas
Lyncoya - Ethan Reed Mckay
Lyncoya - Maeve O'Connor

The story of Andrew Jackson's rise from Indian fighter to President with attendant historical figures. A great production music and scenes.

4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-41867590239068832602013-07-01T23:12:00.000-07:002013-07-01T23:12:00.837-07:00And So It Goes - Artists Repertory TheatreWritten by Aaron Posner and directed by Aaron Posner
Tom Newton - Tim True
Kate Newton - Valerie Stevens
Newt, Stage Manager, John - Andy Lee-Hillstrom
Catherine, Helene, Paula - Kayla Lian
Harry, Roy - Alex Hurt
Verne, George - Leif Norby
Doris, Gloria - Sarah Lucht

The Mask and Wig Club puts on a play every year in a small town. A shy new woman in town is invited to join the cast which includes a shy hardware store stock boy who only comes alive when he is in character in one of the plays. Fun production.4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-29650915989650001102013-07-01T23:01:00.001-07:002013-07-01T23:01:29.227-07:00The Gin Game - Artists Repertory TheatreWritten by D. L. Coburn and directed by JoAnn Johnson
Weller Martin - Allen Nause
Fonsia Dorsey - Vana O'Brien

Man and woman in a nursing home face the reality of aging and the end days of life across a card table on the back patio playing gin.4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-38300644227032276152013-07-01T22:57:00.001-07:002013-07-01T22:57:35.541-07:00Mother Teresa Is Dead - Portland PlayhouseWritten by Helen Edmundson and Directed by Isaac Lamb
Jane - Nikki Weaver
Frances - Gretchen Corbett
Mark - Chris Harder
Srinivas - Luke Bartholomew

Personal responsibility in the face of the gulf between the developing world and the industrialized world. Explores what it means to try to address the problems both from a political and personal basis. Woman leaves husband to go to India to do good leaving behind a child in order to save other children.4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-75558709394810319922013-07-01T15:57:00.003-07:002013-07-01T15:57:57.081-07:00Ten Chimneys - Artists Repertory TheatreWritten by Jeffrey Hatcher and directed by Damaso Rodriquez

Alfred Lunt - Michael Mendelson
Lynn Fontanne - Linda Alper
Uta Hagen - Abby Wilde
Hattie Sederholm - JoAnn Johnson
Sydney Greenstreet - Todd Van Voris
Carl Sederholm - Chris Harder
Louise Green - Sarah Lucht

A ham-handed take off of The Seagull the play is a comedy/drama with a bit of wit and a very slender narrative thread. Not brilliant but perfectly acceptable performances. 4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-48949971508058202622013-07-01T15:43:00.003-07:002013-07-01T15:43:45.516-07:00My Children! My Africa! - Profile TheaterWritten by Athol Fugard; directed by Adriana Baer
Mr. M - Bobby Mermea
Isbel Dyson - Chelsie Kinney
Thami Mbikwana - Gilbert Feliciano

Setting: Camdeboo, South Africa, 1985

Thami, a black student in an apartheid school is in a debate contest with a white girl from a privileged white school under the direction of Mr. M. Mr. M believes his student Thami is outstanding and has a chance to go far within the limits of blacks in apartheid South Africa--Thami turns to revolution, to break the boundaries that Mr. M sees no way to escape in the short run and turns in the revolutionaries and is subsequently killed by them.

Well acted, another excellent play from the incomparable Mr. Fugard.4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-5819316195894571552013-07-01T15:36:00.000-07:002013-07-01T15:36:06.907-07:00Ithaka Artists Repertory Theatrewritten by Andrea Stolowitz
Director - Gemma Whelan
Odysseus/Jacob - Victor Mack
Captain Elaine Edwards - Dana Millican
Lance Corporal Eve Richardson - Danielle Purdy
Bill Edwards - Paul Angelo
E.M. Richardson - Valerie Stevens

mc: Good storytelling, good acting, got me into the emotions and struggles of the context.
sz: Story about PTSS woman returns from war tortured by guilt and questions of her role in an incident in which her friend dies: should she have shot the child instead?

4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-954011982565076292013-02-23T17:00:00.002-08:002013-02-23T17:00:53.150-08:00The Lost Boy - Artists Repertory TheaterWritten by Susan Mach and Directed Allan Nause
Cast: Christian Ross - Michael Fischer-Welsh
 Sarah Ross - Dana Millican
 Detective Heins - Doren Ellias
 Bill Mosher - Duffy Epstein
 Joseph Douglas - Sean Doran
 PT Barnum - Todd Van Voris
 Zalumma Agra - Louisa Sermol
 Tom Thumb/Zahaer - Sam Dinkowitz
 Charlie Ross - Logan Martin
 Walter Ross - Harper Lea
 Cynthia - Elizabeth Houghton
 Ian McKean - Geoff Kanick

Child kidnapping reveals fractures in family that struggles to come to find a way to reclaim their child while dealing with the public fascination and scrutiny. Wheeling and dealing family and showmen all want a piece of the profits that can be made from a tragedy. We weren't impressed with how it all played out.4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-61175983074351471902013-02-23T16:54:00.001-08:002013-02-23T16:54:17.279-08:00Seven Guitars - Artists Repertory TheaterWritten by August Wilson and Directed by Kevin Jones
Cast: Canewell - Victor Mack
 Red Carter - Michael J Asberry
 Vera Dotsun - Ramona Lisa Alexander
 Louise - Gayle Samuels
 Hedley - Mujahid Abdul-Rashid
 Floyd Barton - Lance McQueen
 Ruby - Ashley Williams

August Wilson is one of our favorite playwrights and we love to see any of his plays especially when they are well done as this was. This is 1940s Pittsburgh Cycle play begins and ends with the funeral of the main character. Floyd Barton recently released from jail has an opportunity to go to Chicago and record his music and possible set his life on a different path, but while he might think is done with the past, the past isn't done with him, nor is breaking the codes and patterns around easily accomplished. 4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-71113156495961421272013-02-23T16:44:00.003-08:002013-02-23T16:44:39.869-08:00Circle Mirror Transformation - Artists Repertory TheaterWritten by Annie Baker and Directed by Allen Nause
Cast: Marty - Beth Harper
 James - Richard Elmore
 Schultz - Jason Glick
 Theresa - Val Landrum
 Lauren - Danielle Purdy

Various individuals from a small town meet and participate in a creative drama class. Their real lives have complexities that are demonstrated and ameliorated in the drama class. Kind of new "agey"4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-88218535230252273562013-02-23T16:39:00.000-08:002013-02-23T16:39:12.578-08:00I am Still the Duchess of Malfi - Artists Repertory TheaterWritten by Joseph Fisher and Directed by John Karetzu
Cast: The Cardinal - Todd Van Voris
 Delio - Nicholas Hongola
 Bosola - Chris Murray
 Ferdinand - Jack Street
 Antonio - Vin Shambry
 Cariola - Camille Cettina
 The Duchess - Sara Catherine Wheatley

Well done reconfigured tale of revenge with laughs and serious content. 4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-83930898375247882872013-02-23T16:30:00.000-08:002013-02-23T16:30:02.054-08:00Race - Artists Repertory Theater Written by David Mamet and Directed by Tamara Fisch
Cast: Jack - Todd Van Voris
 Henry - Reginald Andre Jackson
 Susan - Ayanna Berkshire
 Charles - Jim Iorio

Legal issues demonstrate social and cultural attitudes, prejudices, assumptions, complications of our society when it comes to race and gender - did he didn't he rape the black woman, and who should or could bes defend him. Not sure what all we learned from watching this.4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-84527567683044986192012-07-01T16:22:00.003-07:002012-07-01T16:22:59.417-07:00Brother, Sister Plays Part 2 - The Brothers Size and Marcus or the Secret of Sweet - Portland Playhouse
Written by Tarell Alvin McCraney; Directed by Victor Mack
Cast: Shun, Shunta Iyun - Lava Alapa
 Ogun - Bobby Bermea
 Elegva, Legva, Marcus - Brian Demar Jones
 Aunt Elegua, Shun - Jennifer Lanier
 Oya, Osha - Ramona Lisa
 Man from state, O Li Roon - Jonah Weston
 Shango, Oshoosi, Terrell - Damian Thompson
 Egungun, Shua - Salim Sanchez
 Momma Moja, the woman who reminds you, Oba - Jocelyn Seid

Brothers one hard working the other has a dream of owning a car. This is about what is it to be a brother; how many ways is love demonstrated; what kind of sacrifices are required within that love. Beautifully performed; magnificently presented - walked out crying.
4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-43747449744126976172012-07-01T16:19:00.003-07:002012-07-01T16:19:59.798-07:00The Brother Sister Plays Part 1 In the Red and Brown Water- Portland PlayhouseWritten by Tarell Alvin McCraney; Directed by Victor Mack
Cast: Shun, Shunta Iyun - Lava Alapa
 Ogun - Bobby Bermea
 Elegva, Legva, Marcus - Brian Demar Jones
 Aunt Elegua, Shun - Jennifer Lanier
 Oya, Osha - Ramona Lisa
 Man from state, O Li Roon - Jonah Weston
 Shango, Oshoosi, Terrell - Damian Thompson
 Egungun, Shua - Salim Sanchez
 Momma Moja, the woman who reminds you, Oba - Jocelyn Seid

Young woman's dreams of being a runner are deferred to help her mother; dreams which are not available when you look for them later. Pursued by young men: one who offers stability; one who offers sexual attraction. No good or easy choices; protagonist wants a child but is barren. Stunning performance; the reason we go to theater is to discover plays like this.4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-83483233536930143462012-07-01T16:11:00.001-07:002012-07-01T16:11:32.870-07:00Red - Portland Center StageWritten by John Logan; directed by Rose Riordan
Cast: Mark Rothko - Daniel Benzali
 Ken - Patrick Alparone

Clever staging; great text. Explores the nature of the relationship of art and philosophy and ego. Acting was Ok but one craved to see a real powerhouse actor engage the text.4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-47039328317344823122012-07-01T16:07:00.002-07:002012-07-01T16:07:45.031-07:00A Lesson Before Dying - Profile TheaterWritten by Romulus Linney (from a novel by Earnest J Gaines); directed by Kevin E Jones
Cast: Paul Bonin - Dennis Kelly
 Emma Glenn - Brenda Phillips
 Grant Wiggins - Carl Kennedy
 Sam Guidry - Stephan Henry
 Jefferson - Harold Warren
 Vivian Baptiste - Andrea White
 Rev Moses Ambrose - Jerry Foster

Black man accused of a crime is called a pig and condemned to death. He responds by saying that if is called a pig he should act like a pig. His family and community fight to convince him that no one should be defined by someone else and he must act like a man not a pig before he dies. Nicely done!4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-9001971518621151002012-07-01T16:03:00.000-07:002012-07-01T16:03:00.627-07:00Penelope - Third Rail TheaterWritten by Enda Walsh; directed by Philip Cuomo
Cast: Burns - Christopher David Murray
 Quinn - Michael O'Connell
 Dunn - Tim True
 Fitz - Bruce Burkhartsmeier
 Penelope - Britt Harris

What a great play! Well done and well staged. It was nice to have the old Third Rail company back! It is a take on the Illiad from the perspective of the Penelope's (Odysseus's wife) suitors. Penelope representing a future worth living and all the heart is called to but is also ever elusive and the competition among men in the pursuit of the unattainable.4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-4423712805741679162012-07-01T15:58:00.000-07:002012-07-01T15:58:12.053-07:00Hard Times - CoHo TheaterAdapted from The Charles Dickens novel by Stephen Jeffreys; directed by Michael Gerber
Cast: Camille Cettina; Ted de Chatelet; David Janovik; McKenna Twedt

Every member of the cast played multiple parts. Interesting staging; good costumes but we weren't sufficiently caught up in the play to endure the dreadful seating. The seats are too low to sit in comfortably for the duration.4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-40274412277077146392012-07-01T15:54:00.000-07:002012-07-01T15:54:15.624-07:00Next to Normal - Artists Repertory TheaterPlay by Brian Yorkey; Directed by Jon Kretzu
Cast: Diana - Susannah Mars
 Dan - William Wadhams
 Gabe - John Debkowski
 Natalie - Meghan McCandless
 Henry - Todd Tschida
 The Doctor - Jared Q Miller

Mom's fighting mental illness while family struggles to take care of her and themselves; no easy chore. Done as a musical. Too bad cast wasn't up to the task. Good try production.4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-67563697670265116532012-07-01T15:49:00.002-07:002012-07-01T15:49:55.132-07:00The New Electric Ballroom - CoHo TheaterReading play by Enda Walsh
Cast: Breda - Jacklyn Maddux
 Clara - Beth Harper
 Ada - Stephanie Gaslin
 Patsy - Isaac Lamb

Sisters remember pivotal day from their youth. Would be fun to see a full production with all the costume changes and make up as described.4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-28392011552969444952012-01-16T15:55:00.000-08:002012-01-16T15:55:40.925-08:00The Collaborators (National Theater Live) A--Thank you Third Rail for organizing these presentations of National Theater Live here in Portland. We are sorry you did not--for this presentation--as you have for all the others-- hand out an information sheet about the play and cast.

So I am lacking a lot of details as I write .. maybe I'll find the info on line and add it later. But while it is fresh in my mind I want to say..

this is a great play--It is about the nexus between 'art and politics' and covers lots of other territory in the process especially pertaining to personal responsibility and rationalizations while it suggests that governing really is hard -- that would include governing yourself--as well as a nation. Fabulous acting! Highly recommended4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-36527938261652735382012-01-16T15:44:00.000-08:002012-01-16T15:47:46.524-08:00Collapse (Third Rail) Grade Cby Allison Moore
Directed by Slayden Scott Yarbough

Cast:
Hannah ..... Rebecca Lingafelter
David ..... Jim Iorio
Susan ..... Stephanie Gaslin
Ted ..... Shelly Lipkin

sez says: humm -- this is suppose to be a comedy--but it is not charged with laughter. A few giggles here and there --but really funny? no, it is not. Partly that is the play--partly it is the production. The story is about a husband and wife suffering from the husband's lingering trauma (the result of being on a bridge that collapsed-based on a real event in Minnesota). Their lives have not gotten back on track since that event--and as we enter the story, things seem to be getting worse. The wife's black-sheep sister shows up saying she plans to live with them for awhile, and the sister seems to be working as a mule in a drug deal. The wife is worried she may be laid-off from her job. The traumatized husband is drinking more and more. Because the story needs to move-- a mistaken identify motif is introduced via an impotent sex addict -- In the end--husband and wife decide that so long as they are together they will be just fine ....

Now, if this were funny, maybe it would be worth watching.. but it doesn't make it to funny. The subject in not necessarily funny--so it would take some special acting to get it to be humorous. While most of the acting was ok, there was a big problem with Stephanie Gaslin's Susan. She was flat. Gaslin presents Susan by throwing her arms wide in big swooping movements -- over and over and over and over. You can not discover a character via overstated body movements alone. It was as if Gaslin couldn't find a way to bring her character to life--and her character needs to be brought to life to find the humor in the story.

In sum: A bit disappointing. Light entertainment at best. Not the best play--and a mediocre production.4 Geezershttp://email@example.com:blogger.com,1999:blog-6035269952701283818.post-48625485094003680822012-01-16T15:18:00.000-08:002012-01-16T15:18:38.376-08:00Hunter Gathers (Theatre Vertigo) Grade B+by Peter Sinn Narchtrieb
Directed by Tom Moorman

Cast:
Pam ..... Karry Ryan
Richard ..... Mario Calcagno
Wendy ..... Brooke Fletcher
Tom ..... Joel Harmon

sez says ... here is something we have decided-- You Can Count on TheatreVertigo. This band of actors choose the best plays around to produce --and they add plenty of heart and heat to these great plays when they stage them. What more can you ask of any company? Ok -- so they are not National Theater of England level master actors--but they are GOOD. And, they seem to always come up with exceptional works: nothing hum drum is going to get on their stage.

And this is certainly true for their latest: Hunter Gathers. What a ride. A simple story about two couples, 30- somethings, who meet for an annual dinner..but what a dinner. From slaughtering their own lamb for dinner--so the meat will be truly fresh... to the discovery that each members of the dinner party seems to be at a different stage in human evolution, the story moves into territory too often ignored. The beast in men that seeks to determine who is the ALPHA-dominant male. The imperative to procreate. Meanwhile suppressed sexual desires--and not so suppressed sexual desires are let loose --while we, as an audience, are left to ask just how good is it to be "close to nature". Plus there are plenty of laughs to go around. All four actors do yeoman service to their characters --one being more fun than the next. Highly recommended. We give thanks for for a great show.4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-69294909881516323642012-01-02T18:19:00.000-08:002012-01-02T18:19:49.109-08:00Angels in America, Part I: Millennium Approaches (Portland Playhouse) Grade A+By Tony Kushner
Directed by Michael Weaver

Cast
Roy Cohn ..... Ebbe Roe Smith
Joe Pitt ..... Chris Harder
Harper Pitt ..... Nikki Weaver
Belize ..... Berwick Haynes
Louis Ironson ..... Noah Jordan
Prior Walker ..... Wade McCollum
Hannah Pitt + Rabbi + ..... Gretchen Corbett
The Angel ..... Lorraine Bahr

Life has gotten too busy so I can't write the sort of review I would likt to--but I don't want to maiss a chance to at least says that this is a brilliant play and it is beautifully done.

Hats Off the Portland Playhouse for their latest in a string of winners. Bringing together some of Portland's best talent with just the right mix of imported help, making magic happen on stage with minimal sets and thus making The Play Be The Thing is the gift this company brings to our fair city --so we send thanks and look forward to their next offering.4 Geezershttp://firstname.lastname@example.com:blogger.com,1999:blog-6035269952701283818.post-43406166341311129612012-01-02T18:09:00.000-08:002012-01-02T18:09:27.225-08:00The Prisoner of Second Avenue (Profile Theatre) Grade Bby Neil Simon
Directed by Thom Bray

Cast:
Mel Edison ..... Don Alder
Edna Edison ..... Karla Mason
Harry Edison ..... Thomas Bray
Pearl ..... Jane Unger
Jessie ..... Jean Miller
Pauline ..... Jane Fellows

plot -- Don has lost his very good job, wife Edna has to go to work, brother Harry wants to help, sisters Pearl Jessie and Pauline are a riot.

sez says: Neil Simon holds up -- he is a very clever writer --and he also is willing to take on topics that have resonance in our culture. Here we look at unemployment, aging, male pride, family connections and contradictions - all with a light enough touch to make us smile in recognition--and serious enough to make us think about how the world works. (and my --how men's and women's relations have change since this was written-!)4 Geezershttp://email@example.com


text:
In an unexpected move today North Pole Flight Command Center has elevated its operational status to 24-hours per day.
This is unprecedented. Normally the Flight Command Center does not run around the clock until early November.
Speculation at the North Pole is running rampant. Most assume the move is being made to accommodate tracker training associated in the search for Santa.
In an official statement released by North Pole Flight Director Elf Quinton Q. Quigley the Flight Command Center required the elevated status due to changes in the delivery schedule for supplies, shipments and reindeer movement associated with the Christmas season ahead. The statement claims the change is routine.
Recent closed door meetings at Flight Command suggests to some that the search for Santa is more serious than is being reported.
What the change is status means for casual observers is that sleighs will now be taking off and landing at the North Pole at any hour of the day or night. That does not suggest that sleigh traffic will be constant, as it is in the days leading up to Christmas. But it does mean a greater amount of flight activity and the likelihood of more breaking news in the days and weeks ahead.


text: Infiniti previewed this car as a "concept" this year but we weren't fooled. This will be the next M class powered by either the 3.5 liter V-6 or 4.5 liter V-8. The car will make its official debut at the Detroit Auto Show in January. Anything is better than the no selling current M that looks like it was in both a front-end and rear-end collision. Infiniti will also display the Infiniti Kuraza Concept, an "exploratory look at future SUV interior design". Wee.


text:
Keane's first album, Hopes and Fears, was thoroughly engaging, thanks in large part to Tom Chaplin's ethereal vocals, those Tim Rice-Oxley piano hooks, and the balladry of "Everybody's Changing," "Bend and Break," and "Somewhere Only We Know." It did big box office. Got a lot of press. U2 comparisons. Chris Martin analogies. "Timing is everything." "Coldplay Lite," said some. "Wait for the other shoe to drop," said others.
Under the Iron Sea is not as instantly catchy, though Keane is due credit for taking a bold step by infusing a darker sound into a set of tracks with moody electronica. The album has a few really good songs, most notably "Atlantic," "Nothing in My Way," "The Frog Prince," and the majestic title (sound)track. So let's split the difference: This effort is not the trumpeting that A Rush of Blood to the Head was, nor the mixed blessing X&Y was. But it never exactly slumps either, despite a move away from formulaic, radio-ready alt-pop hits. Not transcendent but worthwhile; this will grow on you.
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text:
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Go to (in English) and enter the cell phone number prefix, the number, and your text message. If you read Russian or can figure this page out, you can send an SMS to any mobile phone operator in Ukraine for free at The standard price these days is 100-150 UAH ($20-30 USD), depending on where you need to go to within Kyiv. The Kyiv Boryspil international airport is located 15 km to the southeast of Kyiv. To get from Boryspil to Kyiv you will need to take either a taxi or a "Polit" bus.
Many recent visitors can confirm this with their personal experience.
You can go for cheaper still if you agree to ride with other passengers or are stubborn about lowering the price. to midnight every 20-40 minutes (now supposedly they run 24 hours).
A ticket costs around 15-20 UAH depending on your destination.
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How can I send an SMS message to someone in Ukraine? map=kiev&l=en, select the city at the left and enter the street name in English, Ukrainian, or Russian. If you decide to take a taxi and are not up to haggling with the taxi drivers, the best idea is to walk up to the taxi stand INSIDE of the terminal 50 m from where you come out into the lobby and talk to a young lady there.


text:
I checked this hotel out in March when we knew we'd be arriving from the UK at the same time as our new grandchild, thought then it would 'do'. We arrived to find the upstairs had been completely refurbished and the downstairs bar and bistro should be finished by January. It was room only but when downstairs is done they may do a continental breakfast. It is the only hotel I have ever stayed in where there was enough drawer and hanging space to completely unpack. The ensuite was good and spacious, there was a laundry for guests to use with washer, dryer and ironing facilities and there was a nice sitting room for guests with sofas, tea and coffee, television, books and magazines. It was all clean and tidy and the staff were lovely, really helpful as was the owner. If you are a light sleeper like me you need to ask for a quiet room as the hotel is on the corner of 3 roads, we had one and I slept really well. Middle Footscray station is only a few minutes walk down the road. We stayed twice and would definitely stay again. NB I have rated swimming pool and room service in error - there wasn't any and I can't delete it!More
- Free Parking
- Restaurant


text:
And then I looked up where the epicenter of the quake had occurred. Maule. No more than 40 miles from Chillan and my beloved host family. 40 miles! This is when my real panic began. I woke up Ed in my tears, which soon escalated to sobbing hysteria. I had grown close to my host family and absolutely adored my host brothers: Alonso (age 15), Roberto (13), and John (9). They were my constant companions as I learned to navigate a new town and university speaking only limited Spanish. Each left me with a farewell greeting and a kiss on the cheek (customary, but nonetheless charming). They let me hang out with their friends and attend their parties, and they taught me all of the Chilean slang and customs I needed to know to survive the next six months with minimal gaffs and embarrassment (but I just have to tell you that when someone in Chile asks if you like to ski a lot....it might have a completely different meaning than you expect).
Their parents, Maria and Alonso, were good, hard-working Chileans. They had limited means but much hope for the future. Maria cared for their small home with pride. Alonso worked long hours at odd jobs to provide, traveling back and forth on an old ten-speed bike. Both sacrificed for their children's education and most all of the money they earned housing me went to pay for the boys' school fees. I was always embarrassed that I had my own room and the rest of the family shared a single room with two beds. I constantly invited them to share my room....but rules were rules. The university said I must be provided my own bedroom and they refused to break the terms of their agreement.
A couple hours of Telemundo later, I had calmed down a bit. There were relatively few deaths in the quake, nothing like the disaster in Haiti. I knew they were alive, but feared their house was destroyed. I wasn't sure of their financial situation. Would they be left homeless and destitute? I desperately wanted to talk with them. I had not spoken with them since shortly after Noe's birth. I was embarrassed that I had let so much time pass. On a lark, I looked up my brothers on
In less than three days, I heard from all three of them. They were fine, their family home had been damaged, but not destroyed. Chile has a strong foundation, a country on the verge of 1st world status, and the earthquake proved this to me and the rest of the world. The country was well-prepared for this quake....it could have been so much worse. My brothers, who started their accounting classes in grade school using accounting ledgers from the 1950's, were all three college graduates, tech-savvy, fun-loving and good-hearted men. Alonso, the oldest, has a great job in Santiago with a large accounting firm. The other two work in accounting in their hometown of Chillan. When I lived in Chile, the country was only a few years removed from the Pinochet dictatorship, still on unsettled ground politically and economically (not to mention geographically). The past decade has been good to them, and I have no doubt that Chile will continue to thrive, in spite of this recent crisis.
We have a coin jar in our home with a Chilean flag glued to the front. Every night our loose change and bills goes into that jar to help the recovery effort. It is a small gesture, yet symbolic. A way to contribute. A way to remember my host family until we can visit them again. A way to introduce my children to this country and this people that changed my life forever.