text:
The Carlyle Group LP (Nasdaq: CG) has acquired consumer data provider Claritas from Nielsen (NYSE: NLSN). The PE firm partnered with the Indian Hill Group on the transaction. Financial terms were not disclosed.
New York-based Claritas, founded in 1961, provides consumer data and demographics, including where people work, live and shop, to help businesses better directly market to those clients. The target is known for its Prizm product. Nielsen acquired Claritas in 2009.
"The big data revolution has created rising demand for consumer insights and Claritas is benefiting from that trend," says Carlyle managing directors Adam Glucksman and David Stonehill.
Indian Hill is an investment firm led by former Nielsen and Procter & Gamble Co. (NYSE: PG) executive Mike Nazzaro. Nazzaro is also the CEO of Claritas.
Carlyle made the investment out of its $2.4 middle market Carlyle Equity Opportunity Fund II, which it closed in 2016. In that same year, Carlyle reached a deal to buy wireless technology company NetMotion Wireless Inc. from Clearlake Capital Group LP.
Retailers have been under pressure to keep up with changing customer behavior, driving up a demand for data providers. Blackstone Group LP (NYSE: BX) and New Mountain Capital have invested $570 million in retail data provider JDA Software Group Inc.; HGGC has been making add-on acquisitions to its platform company Survey Sampling, a brand tracker; and Summit Partners invested in retail data company Mi9 Retail.
Morrison Cohen LLP and PriceWaterhouseCoopers are advising Carlyle. Foros is advising Nielsen.

subset: commoncrawl


text:
Monday, 26 October 2009
My plan was to clean the house, which really needed to be
done since I've been busy with craft projects the last week.
Since it's the end of the season for boot sales we didn't find
that much stuff. This is just some of the finds though...
My favorite find is the soup container, I first thought it was
Swedish but after closer inspection I noticed that it's of an
English make.
The guy who sold it to me told me it was from his mother
and she bought it in the 1960's.
I got plans for the flowery dress.
It's a Laura Ashley dress that's not so very flattering at the
top so I'm gonna turn it into a skirt instead.
After the boot sale we went to out favorite restaurant and
afterwards we went to my father in law.
Everything except the flowery dress is from the 50's/60's.
Dresses, £2 & 50 pence.
(Click image for larger version.)
French pictures, 75 pence each.
Soup container, 50 pence.
Cassette case, 50 pence.
11 comments:
- daisymay said...
Gosh where do you carboot to find such cute things, the ones round by me are rubbish. I would never find a vintage dress, let alone a laura ashley one!! Good going. The soup container is very cool!!
- 26 October 2009 at 17:55
- Little Rascal said...
We do some of the ones in Hertfordshire.
I just loved the flower pattern on the LA dress, it's not cute as a dress but it's gonna be wonderful as a skirt.
The soup container is so cute that my toes go numb. :))
- 26 October 2009 at 18:03
- Ms. B said...
Love the pictures and the polka dot dress!!!
- 26 October 2009 at 21:34
- secondhandshopper said...
Love the soup pot!
- 27 October 2009 at 09:50
- Linnea said...
Den blåa klänningen hade jag också köpt! soppskålen är ju riktigt fin den med!
- 27 October 2009 at 14:13
- RecordCollector said...
Wow, great taste you got Lil' Rascal :-)
- 27 October 2009 at 17:30
- A red lipstick said...
I love the blue polka dot dress! You always find so many nice things!
- 27 October 2009 at 19:19
- Pixie. said...
Oooh, I love the blue and white dress. Beautiful. Can't wait to see what you do with the LA dress- wish I had your creativity!
- 27 October 2009 at 22:05
- jewlover2 said...
Such great finds!
- 28 October 2009 at 01:25
- Zizzi said...
Jag tycker också om soppskålen. Och kassettväskan!
- 28 October 2009 at 21:22
- miss Karla said...
Snart åker jag till London bara för att fynda!! Jag tycker jag brukar vara bra på det där men jämfört med dig ligger jag ju i världens största skugga! ;)
- 30 October 2009 at 21:18


text:
3.5 / 5
Tagline: Bit by bit...By bit he carved a nightmare!
Directed by: Dennis Donnelly
Written by: Neva Friedenn, Robert Easter
Actors include: Cameron Mitchell, Pamelyn Ferdin, Wesley Eure
Genre: Horror
Length: 93 minutes
Banned: Norway
Country: USA
This one actually starts off to be a load of fun with serious '70s decor and outfits and creative killings. There is a maniac in an apartment building with a toolbox...of death! He goes around to the apartments of attractive women who love to be naked and kills them in fun and bloody ways. I actually seriously love the killings in this one, and the atmosphere but the thing is they try to make some sort of scooby doo story towards the end and it gets boring and the action totally stops about halfway through. It's too bad they couldn't come up with a stronger finishing move because this could have been a really great slasher. On that note the remake is extremely different from this one, they changed it a TON.
Availability: On DVD


text:
Lookup NU author(s): Dr Diana MacCallum
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Editor(s): MacCallum D; Haswell J
Publication type: Edited Book
Series Title:
Year: 2003
Publisher: Black Swan Press
Place Published: Perth, Australia
Library holdings: Search Newcastle University Library for this item


text:
The Sensory Overload Dives Into The Deep End
In 2002, Rez released in the United States on PlayStation 2 to widespread acclaim. The project, produced by Tetsuya Mizuguchi, received widespread acclaim for its intense rhythm-based action gameplay and its thumping soundtrack. With Rez Infinite, the classic game is more intense than ever as it now features 1080p resolution, 3D audio, and support for PlayStation VR.
As I walked into a meeting with Enhance Games, I notice a more elaborate setup than I've seen with other virtual reality games I've demoed in the past. Adjacent to the usual television used by the team to monitor what I'm seeing my headset, two bust forms with intriguing outfits stand prominently. The one on the left I recognize as the Synesthesia Suit that Mizuguchi wore during the reveal of the project on stage at the PlayStation Experience keynote, but the one on the right is what has piqued my interest.


text:
Hello Malaysia! Our first pop up store is now in ISETAN KLCC for the next two weeks from 27 Oct to 09 Nov 2017, 10am to 10pm. FUNFIT will be showcasing our latest WOMEN FALL 2017 swim and active collection. Welcome everyone to drop by to support us!
- - - - -
* Receive 1 x FREE sports headband (worth RM22) when you signed up for free FUNFIT membership at our pop up store.
* Receive 1 x FREE fabric swimcap (worth RM26), when you spend above RM250.
* Receive 1 x FREE resort pareo (worth RM119), when you spend above RM400.
While stocks last. T&Cs apply.
- - - - -
Any question? Feel free to contact us!
Instagram | @welovefunfit
Email | [email protected]
Website | www.welovefunfit.com


text:
Interested in a good scare this Halloween? Look no further than your own computer, mobile or tablet device!
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text:
It's tough being a door to door salesman these days. Too many stories of burglars knocking on the door. If no one answers, they break in and take what they can. If someone does answer, they come up with an excuse such as they are selling something for charity.
This story will not help.
According to the Gold Bar Firefighter's Association Facebook page, a group of people, posing as firefighters were going around the Gold Bar area wanting to check homeowner's smoke detectors. The Firefighter's Association says that this is a scam to sell fire alarms. It emphasizes that firefighters do not make cold calls. If they come out to your house it will be at your request, in uniform with a department vehicle.
Other postings on social media have talked about a similar team in the Marysville area and North Everett. One posts described two young men, one wearing basketball shorts the other wearing all black clothes. The person making the post noted that the two did not want to take no.
Whether this is a scam or burglars trying to check out houses be wary of anyone claiming to be from a local government or utility who cannot produce identification from that organization or is pushy about entering your home.
Call 911 if anyone acts suspiciously at your door. A timely call can help deputies find a potential burglar or scammer.
Gold Bar Firefighter's Association:


text:
The 361-square-kilometre (139 sq mi) municipality is the 255th largest by area out of the 422 municipalities in Norway. Sørreisa is the 247th most populous municipality in Norway with a population of 3,496. The municipality's population density is 10.1 inhabitants per square kilometre (26/sq mi) and its population has increased by 5.5% over the last decade.
The municipality of Sørreisen was established on 1 September 1886 when it was separated from the municipality of Tranøy. The initial population of Sørreisen was 1,361. Later the spelling was changed to Sørreisa. On 1 January 1964, the part of Sørreisa across the Reisafjorden on the island of Senja (population: 129) was transferred to the municipality of Lenvik.
The municipality is named after the Reisafjorden (originally Reisa), which again is named after the Reisaelva (the "Reisa river" - originally Reisa). The river name is derived from the verb rísa which means "raise" (referring to flooding). The first element Sør ("south") was added to distinguish the municipality from Nordreisa. The municipality was originally named Sørreisen.
The coat-of-arms is from modern times. They were granted on 7 September 1984. The arms show three gold stars on a red background. It was derived from the oldest known seal in the municipality, a 17th-century seal of Jacob Hansen Kinapel, who was a police sergeant in Sørreisa from 1715 to 1748.
The Church of Norway has one parish (sokn) within the municipality of Sørreisa. It is part of the Indre Troms prosti (deanery) in the Diocese of Nord-Hålogaland.


text:
Know more about this business than we do? Cool! Please submit any corrections or missing details you may have.Help us make it right
Be the first cleveland.com user to add photos or videos of Stewart & Stewart Lawyers
Steve Temple Associates is located at 104 W Main St in Tipp City and has been in the business of Temples since 2011.
Since 2008, Stewart And Stewart Lawyers, Ltd. has been providing Legal Services from Tipp City. Stewart And Stewart Lawyers, Ltd. has estimated annual revenues of $120,000.00 and also employs an estimated 2 employees.


text:
local newspaper advertising rate card
Pricing Local display advertising rates are non-commissionable.Newspaper Rate Card The Newspaper may revise its advertising rate schedule at any time upon 30 days written notice to Advertiser, and Advertiser may, without penalty, cancel its advertising contract at any time prior to Political advertising rates are the same as net local rates, and all earned and contract discounts are available.Advertiser agrees to pay all bills within Newspapers terms, and to abide by all other policies of Newspapers printed rate card. Newspaper Ad Rate Card - 2017.Check Midday Newspaper Advertising Options Ad Rates.Indias most engaging local newspaper, MID DAY, has become the quintessential physical connect for the uber-social generation to consume their local city news today. book classified ads online. Local newspaper ad rate. ads in times of india. deccan chronicle advertising rates. Times Classified rate card. Advertising Rate Card. HOME News — Local News Opinion — Letters Our Community — Obituaries — Community Announcements — Local Sports Local Happenings — Daily Calendar of Events — Featured Events Marketplace — Yard Sales — Classified — Coupons — Open Houses A newspaper rate card The rare card for a local British newspaper is shown below.abrasive surfaces activity advertiser advertisement advertising agency advertising policy advertising rates aesthetic application architecture arrange arrangement artificial audience (target a.) be noted for blend Adweek has a clean and simple rate card that should appeal to advertisers because of its layout and format.Unlike national media sites like BBC.com and Adweek.com, local media sites generally have much lower rates. The Ottawa Citizen, a large metropolitan newspaper, has online rates similar to (Redirected from Local newspaper). Jump to: navigation, search.For example, both The New York Times and The Wall Street Journal offer a regional edition, printed through a local contractor, and featuring locale specific content, the Journals global advertising rate card provides a good example ADVERTISING RATE POLICIES Local retail advertising rates are determined by the volume of space used during the calendar month.7. STANDING CARDS To earn these lower rates, ads must run consecutive number of times ordered, with no copy changes.
Advertising Rate Card. View online at highlandscurrent.
com/advertise Michele Gedney20 New York Press Association awards since 2013 for coverage of local news, breaking news, sports, features9 National Newspaper Association awards in 2016 for reporting and advertising design. Only Register an Account to DownloadMetro Newspaper Advertising Rate Card PDF.Source:www.sbj.net Providencejournal.com: Local News, Politics, Entertainment Jan 1th, 2018 PROVIDENCE, R.I. -- With A Wintry Mix Of Weather Moving Into The Region, Some School In The Rate Card. At UKClimbing.com and UKHillwalking.com we believe the best way to make the most out of your advertising is by using a basket of different advertising methods across our site. Providencejournal.com: Local News, Politics, Entertainment Jan 12th, 2018 PROVIDENCE, R.I. -- With A WintryThere is a lot of books, user manual, or guidebook that related to Metro Newspaper Advertising Rate Card PDF, such as : steel structure design and behavior solution manual. Rate (excluding VAT). 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Recruitment ads in the newspaper are one of the most frequently used categories and are the most sought after categories.Once this is done, the ad rates will be displayed instantly as per the Deccan Chronicle Situation Vacant Classifieds Rate Card! These high quality, laser-printed newspapers are tabloid-sized replicas of the current day versions of highAdvertising rate card. CIRCULATION NewspaperDirect South Africa is a relatively new business concern, started in October 2005 which services both local subscribers and international ADVERTISEMENT RATE CARD (Updated January 2016). Serving Williams Fulton Counties In Northwest Ohio Phone (419) 485-4851 Fax (877) 778-9425 www.thevillagereporter.com. You have numerous choices for advertising in great local newspapers. Newspaper rate cards can be purchased directly by through your local newspaper.What do newspaper rate cards do? A rate card for a newspaper is as simple as it sounds. It basically shows potential advertisers the cost (or the rate) it is to buy advertising the the newspaper. Rate Card.Advertising on British Newspapers Online the facts. Over 80,000 unique visitors every month Over 10,000 page views every day Over 1,500 pages covering the full range of national, regional and local newspapers right across the UK Flexibility to address a UK-wide audience or a Some larger newspapers may have a rate card for a particular kind of advertisement. They may have their rates broken down by classified ads, retail advertising, and even national ad rates. Rate cards help the retailer understand what types of ad sizes, discounts Check out our Audience finder. New Advertising Rate Cards For All Newspapers. We are working on the new rate cards, and will have them available asap.In the meantime, our existing rate cards can be found here. Member: Society of Classified Advertising Managers Association, Alliance for Audited Media, SNPA, Independent Newspaper Group and Inland Press Association Capital City Press LLC Local Classified Advertising Rate Card No. 70, Effective July 1, 2016. All rates are VAT inclusive.Tel: 0414 337 000. Fax:235843. Advertising Department: JR Building JINJA Road E-mail: advertisingnewvision.co.ug. Advertising Rate Card 2017. Serving Camden County Since 1894.he Tribune Georgian is Camden Countys newspaper. It is the only. complete source of local news and has the best market coverage of any media in the County. Advertising in local or community newspapers is less so and may provide a more focused advertising approach. If your business trade is localized, it certainly makes more sense toThis company was notorious for adhering to their rate card. But I was determined to negotiate a discount. The Seminole Producer Rate Card. National Rate.6.30 per column inch. 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text:
Delaney Reed, Police Chief of Ordinary, Oregon, knows that mythology gods and creatures such as werewolves and vampire are real. She is in charge of making sure they follow the rules while vacationing in Ordinary. The Rhubarb Festival is right around the corner and tourist are pouring in from everywhere just to try the new rhubarb recipes. With the new tourist come new gods and more trouble than what Delaney can handle.
To make things more stressful, her ex-boyfriend Cooper Clark has just arrived and wants to rebuild their relationship he left behind. However, Delaney has moved on and has her eyes set on Ryder Bailey, her long time childhood crush. Nothing is as it seems in Ordinary and Ryder Bailey might not be who he is. A god has also been murdered and its up to Delaney to figure out what is going on but with a short list of suspects its turning out to be harder than what she thought.
Delaney has to solve this murder case while trying to pursue the growing attraction with Ryder Bailey. She will have to call on the residing gods to aide in the murder case in hopes to bring justice to the god Heim. Time is running out and Delaney still has to find a mortal willing to take on the dead god's power otherwise the result could be catastrophic.
My Thoughts:
I was not expecting to like this book as much as I did. If i'm being honest, the reason why I liked it so much was due to the huge similarity with the Elemental Assassin series. If you guys already read that review you'll know that I was completely hooked to it. These two series have similar characters and story line. Both characters solve crimes, have a love triangle, have different supernatural friends to count on, both characters have some sort of power that needs to be kept secret. There's just a lot of similarities so its no wonder that I would enjoy Death & Relaxation.
However, I do have some criticism to give like how most of the mysterious occurrences were a little too easy to solve. The only mystery that is still to be reveal is Ryder Bailey and who he really is. It's clear that he is trying to protect Delaney from something but he's a jerk for just leaving her like he did.
I enjoyed the laid back pace of this book and the humorous aspects of it. The thought of having gods vacationing in a mortal world was clever and made it enjoyable. One of my concerns before reading this book was that it would have too many plot holes or that the plot would not make any sense. I didn't have to worry though because the author did an amazing job with the world building and the plot was well written.
Although most people seemed to not like this book and its story line, I really recommend people to give this a go if they like a laid back book with humor and crime solving mixed in. I guarantee you'll like it if you liked the Elemental Assassin series by Jennifer Estep.
My Rating: 4.5/5
❀ The Dirty Book Worm ❀


text:
Show Segments
Part 2: A guided meditation for your healing with Dr. Joyce Hawkes
Dr.Joyce Hawkes leads us through a beautiful meditation to send light and healing to victims, families, Seattlites, and others effected by the Seattle shootings.
About our Guest:
Joyce Hawkes, PhD, a biophysicist and cell-biologist by training, is a Fellow in the American Association for the Advancement of Science and author of 36 scientific publications. After a near-death experience, she embarked on an exploration of indigenous healing traditions in Southeast Asia and now teaches energy healing at the interface of science and spirit.
Author of Cell-Level Healing: The Bridge from Soul to Cell, Hawkes is an international speaker and has appeared on national and international radio and television programs, including an interview with Dr. Mehmet Oz on Oprah Radio. She was also featured in a documentary in Japan that showed her brain-wave patterns during a healing session, thermography measurements of the heat from her hands during healing, and interviews with some of her clients. She continues to bring her combined expertise as a scientist and as a healer to enrich each viewers' and workshop participants' personal healing practice and to help them establish a healing outreach for others.
Podcast: Play in new window | Download
Subscribe: Apple Podcasts | Android | RSS | podcast


text:
By Oluwatobi Opusunju
The red dress saga seems not to be ending anytime soon as Mercy Aigbe has now issued a treat to sue both the bride and the designer, Rikaotobyme for defamation of character.
This follows the letter that was made public on Tuesday by the bride's lawyers, Capitalfield Attorneys threatening to sue both Rikaotobyme and Mercy Aigbe in court for conspiracy.
Mercy Aigbe's lawyers, Nwokeji Ibeakokwu & Co. stated that the accusation that there was a "deliberate and fraudulent conspiracy" between Rikaotobyme and Mercy Aigbe by the bride's lawyers is a "malicious allegation."
The letter noted that Mercy Aigbe "did not at any time meet with the designer nor had dealings with her", as she had contracted a stylist, StyledBySeun to style her for her birthday shoot, therefore what is being propelled in the media is damaging to the actress' image.
The letter claimed that the bride's lawyers did not get their facts right before publishing the said allegation that has now gone viral.
As a result of this, Aigbe's lawyers have demanded that a public apology be tendered online by the bride same way the initial letter was, absolving their client of any wrong in the brewing saga.
The lawyers said if the apology is not done within 7 days, both the bride and the designer will be taken to court to face the law for defamation of character.
See the letter below:
Comments are visible after approval


text:
CNX Coal Resources LP, a Delaware limited partnership ("CNX Coal Resources") formed by CONSOL Energy Inc. (NYSE: CNX) ("CONSOL"), announced today that it has launched its initial public offering of 10,000,000 common units representing limited partner interests. The common units are expected to trade on the New York Stock Exchange under the ticker symbol "CNXC." The underwriters of the offering will have a 30-day option to purchase up to an additional 1,500,000 common units to cover over-allotments, if any.
The common units being offered in the offering represent a 42.2% limited partner interest in CNX Coal Resources (or a 48.5% limited partner interest if the underwriters exercise in full their option to purchase additional common units). CONSOL will own a 55.8% limited partner interest in CNX Coal Resources (or a 49.5% limited partner interest if the underwriters exercise in full their option to purchase additional common units). In addition, CONSOL will own, through its ownership of CNX Coal Resources GP LLC, the general partner of CNX Coal Resources, a 2% general partner interest and the incentive distribution rights in CNX Coal Resources.
BofA Merrill Lynch, Wells Fargo Securities, Citigroup, Jefferies, Scotia Howard Weil, Credit Suisse, J.P. Morgan, Evercore ISI, BB&T Capital Markets, Goldman, Sachs & Co., The Huntington Investment Company, Stifel and Nomura are acting as book-running managers of the offering. Clarksons Platou Securities, Cowen and Company and Tuohy Brothers are acting as co-managers of the offering. The offering of common units is being made only by means of a written prospectus. Once it becomes available, potential investors can obtain a written prospectus that meets the requirements of Section 10 of the Securities Act of 1933 from:
BofA Merrill Lynch
222 Broadway
New York, NY 10038
Attn: Prospectus Department
email: [email protected]
Wells Fargo Securities
c/o Equity Syndicate Department
375 Park Avenue
New York, NY 10152
Toll-Free: 1-800-326-5897
c/o Broadridge Financial Solutions
1155 Long Island Avenue
Edgewood, NY 11717
Toll-Free: 1-800-831-9146
Attention: Prospectus Department
520 Madison Avenue, 2nd Floor
New York, NY 10022
Telephone: 1-877-547-6340
E-mail: [email protected]
Scotia Howard Weil
Attention: Equity Capital Markets
Email: [email protected]
Credit Suisse
Attn: Prospectus Department
One Madison Avenue
New York, NY 10010
Telephone: (800) 221-1037
Email: [email protected]
J.P. Morgan Securities LLC
c/o Broadridge Financial Solutions
1155 Long Island Avenue
Edgewood, New York, 11717
Telephone: (866) 803-9204
Evercore ISI
Attn: Equity Capital Markets,
55 East 52nd Street, 36th Floor, New York, NY 10055,
Telephone: (212) 653-9054
Email: [email protected]
BB&T Capital Markets
Attn: Prospectus Dept
901 East Byrd St, 3rd fl
Richmond, VA 23219
Email: [email protected]
Goldman, Sachs & Co.
Attn: Prospectus Department
200 West Street
New York, NY 10282
Telephone: (866) 471-2526
Email: [email protected]
The Huntington Investment Company
200 Public Square
Cleveland, OH. 44114
Telephone: (216) 515-6328
Email: [email protected]
Stifel, Nicolaus & Company, Incorporated
1 South Street, 15th Floor
Baltimore, Maryland 21202
Telephone: 855-300-7136
Email: [email protected]
Nomura Securities International, Inc.
Equity Syndicate Department 5Th Floor
Worldwide Plaza
309 West 49th Street
New York, New York 10019-7316
Clarksons Platou Securities
410 Park Avenue| Suite 710
New York, NY 10022
(212) 314-0900
Cowen and Company, LLC
Fax: 631-254-7140
Tuohy Brothers Investment Research
A registration statement relating to these securities has been filed with the Securities and Exchange Commission ("SEC"), but has not yet become effective. These securities may not be sold nor may offers to buy be accepted prior to the time the registration statement becomes effective. This press release shall not constitute an offer to sell or the solicitation of an offer to buy the securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or jurisdiction.
When available, to obtain a copy of the prospectus free of charge, visit the SEC's website, www.sec.gov, and search under the registrant's name, "CNX Coal Resources LP."
About CNX Coal Resources
CNX Coal Resources is a growth-oriented master limited partnership recently formed by CONSOL to manage and further develop all of CONSOL's active thermal coal operations in Pennsylvania. Its initial assets include a 20% undivided interest in, and operational control over, CONSOL's Pennsylvania mining complex, which consists of three underground mines and related infrastructure.


text:
Hay: "You know your Sinterklaas? Well, where does his Moor come from?"
Chairman: "Saddleworth."
Yesterday Hay's dad surpassed even the hideously wrapped parcel I exhibited earlier in the week, as you can see below. Two entirely different colours of wrapping paper, with no attempt whatsoever to make it at least look arty.


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Growing tensions between North Korea is an obvious concern for United States foreign policy as well as other nations around the world. How China will react to North Korea will also determine the United States' future relations with President Trump and Chairman Xi Jinping. In this article the China is coming up short. Two days after North Korea failed at launching a missile, China is opposed to putting in an American built missile defense system (THAAD) in South Korea. China is also economically punishing South Korea for their involvement in Thailand. On Monday the Vice President reiterated the American plan for deployment, with South Korea's support. Of course China does not welcome a missile defense system to South Korea because it could be a potential threat to their military defense systems. At this moment, China is standing in the way of the United States erecting THAAD in South Korea.
Emily Adams


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Davidson faculty are solving important problems, developing useful tools, and contributing to our understanding of the world.
Davidson College offers competitive benefits for our employees.
Apply now
Job no: 492775
Categories: Staff
Department: Athletics - Womens Soccer
Davidson College invites applications for the position of Assistant Women's Soccer Coach. Primary responsibilities include, but are not limited to, training student-athletes; recruiting; scheduling; assisting with team travel; equipment management; and working with the head coach in directing all phases of a Division I program, including organizing and supervising all practices and games. Davidson competes in the A-10 conference.
Required Qualifications: Bachelor's degree; knowledge of NCAA rules and regulations; at least one year of college coaching experience; possession of good interpersonal and communication skills, as well as good organizational skills.
Preferred Qualifications: USSF "C" License or NSCAA National Diploma, knowledge of ARMS recruiting software program, and understanding of video editing programs (InStat)
The successful candidate should be able to demonstrate effectiveness in coaching college level players, good supervisory skills, and the ability to relate to students in a leadership role. Additionally understanding of student athletes in a demanding academic environment and a commitment to the highest ideals of leadership, sportsmanship and academics are required.
Apply online at http://employment.davidson.edu This is a full time position with regular employee benefits, salary commensurate with experience.
Review of applications will begin immediately and the deadline for applications is June 1st, 2018. Please submit a resume and cover letter with the application.
At Davidson College, we believe the college grows stronger by recruiting and retaining a diverse faculty and staff committed to building an inclusive community. In order to achieve and sustain educational excellence, we seek to hire talented faculty and staff across the intersections of diverse races, ethnicities, religions, sexual orientations, gender identities, ages, socio-economic backgrounds, political perspectives, abilities, cultures, and national origins.
Advertised: 14 May 2018 Eastern Daylight Time
Applications close: 01 Jun 2018 Eastern Daylight Time
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Snoop Dogg aka Snoop Lion Drops – La La La [VIDEO]
Snoop Dogg recently released his new reggae themed song "La La La" after a bit of name change. Now he's dropped the live/animated video to go with it. Snoop kicks the video off with some questions from a few kids who quickly let 'Uncle Snoop Dogg' know what name they prefer. Check out 'Snoop Lion' in "La La La" with all of it's colorfulness and obscene animated fruit included.
In my opinion, no other artist can honestly say they have been able to recreate themselves over and over as much as Snoop Dogg has. Excuse me, no one has been able to recreate themselves like "Snoop Lion" has! Regardless of what 'Snoop' decides to change his name to, and how much marijuana he smokes, he will always be the 'Dogg Father' or better known as 'SNOOP DOGGY DOGG'.


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When: Fri., July 14, 1:15 p.m. 2017
When he's not playing with Modern Grass or Ben Caplan and the Casual Smokers, MacLennan see-saws his bow between jazz, bluegrass and Celtic styles.
Price: free
Lower Water and Salter Street (Waterfront)
Remember, it's entirely possible to disagree without spiralling into a thread of negativity and personal attacks. We have the right to remove (and you have the right to report) any comments that go against our policy.
Select a star to rate.
© 2018 The Coast Halifax


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Not an important question, but I'm just wondering if there is a specific reason Tuesday was chosen? Seems like Friday would be more ideal, because it's the last day of the week, and people are preparing to relax for the weekend.
Last day of the work week for "most" people I meant to say.


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Vote sparks ICAEW exodus
The English ICA faced the prospect of a lingering death this week after members narrowly blocked the introduction of optional papers into its exam syllabus.
With the Big Five alone providing 60% of institute trainees, leading firms are now expected to convene a top-level summit to decide whether or not to stop using the institute to train their students. KPMG described the vote as 'very disappointing'.
Thousands of future institute members could now be lost to rival training bodies as leading accountancy firms gear up to carry out their threat to withdraw their trainees from the institute.
The firms had argued that optional papers, or 'electives', were a vital part the institute's training reforms. Some have already been discussing plans to train students through the Scots ICA or ACCA.
English ICA education officials began a desperate series of talks aimed at finding a compromise to keep major firms on board.
Tuesday's vote at the institute's agm saw electives defeated by 8,117 votes to 8,002. The defeat was also a snub for the institute's elective-supporting council.
Salt was rubbed into the wounds as it emerged that only one in seven of the institute's members bothered to vote.
New president, Dame Sheila Masters, who was yesterday due to be given her chains of office, now faces a tough job dealing with the fallout.
In a recent interview with Accountancy Age, she scotched suggestions that the Big Five's threats to abandon the institute were merely posturing.
She pointed out it would be relatively easy for firms to migrate to the Scots ICA, which has signalled its intention to introduce electives.


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How to Rescue the UFC Middleweight Division
Credit: #UFC212 via Twitter.
How to Rescue the UFC Middleweight Division
There are some divisions in the UFC that have seen truly great champions. The middleweight division most certainly falls into that category with Anderson Silva, who dominated the division for seven years. With the current champion Michael Bisping struggling with injury and Yoel Romero due to take on Robert Whittaker for the interim title, can the division hope to regain its glory days?
Anderson Silva held the UFC Middleweight title for 2457 days between 2006 and 2013. Chris Weidman had an 888-day reign between 2013 and 2015 before injury ended his run, but it's becoming increasingly difficult for the title to regain its former prestige.
Injury Hits Bisping Title Reign
The UK's Michael Bisping finally won a world title when he defeated Luke Rockhold to win the middleweight strap in June of last year. He's hardly set the division alight though with just a rematch win over Henderson last October. He was supposed to be taking on former welterweight champion Georges St-Pierre at UFC 213 but that's been postponed with the challenger saying he won't be ready until at least October. Bisping vs. Yoel Romero was the next plan but then the champion announced he had a knee injury so the middleweight division finds itself in a total mess.
The UFC plans to get itself out of the predicament it finds itself in by going down the aforementioned interim title route, with Yoel Romero taking on the Australian Robert Whittaker. It's a fight with the potential to reignite interest, not least amongst those looking to place bets on the contest: Romero is 8/13 at present to win the title and then set up that unification match with a fit-again Bisping, with St-Pierre likely to face the winner. That gives the division a decent plan for the next year.
Challengers on Unbeaten Runs
Romero is the current number one challenger to Bisping. His record is an impressive one with eight wins out of eight in UFC and his only MMA defeat was in his first bout to Rafael Cavalcante in Strikeforce six years ago. His most recent win was a third-round victory at UFC 205 against former middleweight champion Chris Weidman. That's his only trip to the Octagon since December 2015, though.
Australian Robert Whittaker is currently ranked number three by the UFC and has won nine of his 11 UFC contests (19-4 overall). He's on a seven-fight winning streak since a first round loss to Stephen Thompson at UFC 170 in February 2014, which was his second loss in a row. He's certainly made a great comeback since those couple of defeats, though, and most recently beat Ronald Souza in April. His second-round win won "Bobby Knuckles" the performance of the night award.
The middleweight division has certainly seen better days but fighters of the calibre of Anderson Silva don't come along that often. It's going to be a struggle getting back to the levels that the division was at a few years ago. In the current pound-for-pound UFC rankings, Bisping is at number ten. Sadly, injuries do occur and they're affecting the title reign of "The Count". Building up a Bisping versus Romero unification title fight looks to be the way that UFC boss Dana White sees the middleweight division being rejuvenated. We can but hope that will be the beginning of a return to the good old days at 185 lbs.


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Wimm-Bill-Dann Foods OJSC [NYSE: WBD] today announced that its Chief Executive Officer, Tony Maher, will step down as Chief Executive of the company effective May 1, 2011. His decision to leave the company follows the successful conclusion of the landmark transaction between Wimm-Bill-Dann Foods and PepsiCo. An announcement on Mr Maher's successor will be made in the coming weeks. Tony Maher commented: "The last five years as Chief Executive of Wimm-Bill-Dann have been some of the most exciting and satisfying of my career. I am pleased that I have accomplished almost everything I set out to do when I joined the company. I was lucky to have had a rare professional opportunity to shape the future of one of Russia's most advanced companies and have a strong influence on the overall development of the Russian consumer market. My focus has always been to develop the company, its people and its products for the long-term. I have had the privilege of working with a fantastic team of people on every level of the company. Now I really believe Wimm-Bill-Dann and its remarkable people have a great future ahead as part of a more global organization." Sergey Plastinin, Chairman of the Board of Directors of Wimm-Bill-Dann, said: "On behalf of the board of directors and Wimm-Bill-Dann's founders I want to thank Tony for a job well done and for delivering on his promise to create long-term shareholder value. When he first joined us, our market cap was just over US$1 billion and less than five years later the company was valued at nearly US$6 billion. He streamlined the company, recruited top Russian and international management talent, concentrated resources on winning brands and opened up a whole new market segment with our Zdraivery umbrella brand for kids – all in a very short period of time and in the face of very challenging market conditions. He enhanced our leadership in dairy and baby food and led a brilliant recovery in our juice business. Throughout, he stuck to Wimm-Bill-Dann's core principles of entrepreneurship, transparency and an open corporate culture and he will go down in history for leading Wimm-Bill-Dann to join PepsiCo in one of the most significant deals for modern Russia. We truly wish Tony every success in the future."
Some of the information contained in this press release may contain projections or other forward-looking statements regarding future events or the future financial performance of Wimm-Bill-Dann Foods OJSC, as defined in the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. We wish to caution you that these statements are only predictions and that actual events or results may differ materially. We do not intend to update these statements to conform them to actual results. We refer you to the documents Wimm-Bill-Dann Foods OJSC files from time to time with the U.S. Securities and Exchange Commission, specifically, the Company's most recent Form 20-F. These documents contain and identify important factors, including those contained in the section captioned "Risk Factors" in our Form 20-F, that could cause the actual results to differ materially from those contained in our projections or forward-looking statements, including, among others, potential fluctuations in quarterly results, and risks associated with our competitive environment, acquisition strategy, ability to develop new products or maintain market share, brand and company image, operating in Russia, volatility of stock price, financial risk management, and future growth.NOTES TO EDITORS Wimm-Bill-Dann Foods OJSC was founded in 1992 and is the largest manufacturer of dairy products and a leading producer of juices and beverages in Russia and the CIS. The company produces dairy products (main brands include: Domik v Derevne, Chudo, Imunele, Bio Max and more), juices (J7, Lubimy Sad, 100% Gold), Essentuki mineral water and Rodniki Rossii natural water, Zdraivery kids' brand and Agusha baby food. The company has 39 manufacturing facilities in Russia, Ukraine, Central Asia and Georgia with over 16,000 employees. In 2005, Wimm-Bill-Dann became the first Russian dairy producer to receive approval from the European Commission to export its products into the European Union. In 2010, Standard & Poor's Governance Services confirmed on WBD its governance, accountability, management, metrics, and analysis (GAMMA) score "GAMMA- 7+". The score is the highest among Russian companies and reflects the effective work of the Board of Directors and, in particular, the real influence of independent directors in the decision-making process and the adherence of the controlling shareholders to the highest standards of corporate governance.


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Hillsboro, IL
Elementary Special Education Tutor
I have such a passion for education and young children. I always have. I knew that I wanted to teach when I was a high school student. I spent my Jr. and Sr. years of high school volunteering and apprenticing in special education classes, daycares and read more


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Mom always makes it on the same day as homemade noodles since they both use milnot.
2 c sugar
2/3 c milnot
1 tsp vanilla
1 c peanut butter
1 c marshmallow cream
- Over Med/Med-High heat, boil sugar and milnot to soft ball stage (use candy thermometer!). Do not go past soft ball stage or your fudge will not be so soft and dreamy!
- Remove from heat.
- Add marshmallow cream, peanut butter, and vanilla.
- Pour 9x9 pan that has been filled with foil- butter foil first!
- when set, cut into small pieces and place on serving plate


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Pirouette had her ladybits doctored on Wednesday and after a couple of rough days she felt perky enough to start biting off the stitches. So we made her a little suit to stop her having access to the area. You can see she's not terribly impressed with her outfit. Pirate didn't think much of it either.
C'est la vie, n'est-ce pas?


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- Overview
- Related Products
THORNHILL CRAVER UNIBOLT choke valves are available for pressures up to 20,000 psi with either alloy steel or 12% chrome stainless steel body. They are provided with a ring-groove or taper-type seal, depending on size and pressure. Bean sizes can be specified from 1/64 to 2 in [0.040 to 50.8 mm]. Engineered for heavy-duty, maintenance-free performance, the THORNHILL CRAVER UNIBOLT choke valve is commonly selected for a number of applications, including
- wellheads
- well testing
- manifolds
- process facilities.
The unique coupling between the blanking plug and the body ensures reliability and safety compared with other methods. The connection is made by means of the interlocking shelf design rather than by conventional threads or flanges.


text: SAN FRANCISCO, Dec 11 (Reuters) – Global warming could melt the Arctic's ice during the summer as early as 2040, raising serious environmental as well as commercial and strategic issues, experts said on Monday. "The effects of greenhouse warming are starting to rear their ugly head," said Mark Serreze, a scientist at the National Snow and Ice Data Center at the University of Colorado in Boulder. Marika Holland, a scientist at the National Center for Atmospheric Research, projects a slow, steady decline of Arctic ice as global warming continues, with a dramatic "tipping point" in about two decades. Read more


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Sunday, January 25, 2009
PED 255- The first attempt
During my PED 255 class here at Cortland everyone in the class had to come up with a lesson to teach off the top of our heads. We were given a few minutes to decide what type ball we wanted to use, a volleyball, basketball, football or soccer ball. For my lesson I taught the rest of the class how to catch a soccer ball like a goalie. With only the short amount of time that there was to teach the lesson I think that I was able to give the rest of my classmates a very good beginner lesson on the proper hand positioning of how to catch the ball, and also what to do with it after they had caught it. Everyone else that was in my group also did a good job of explaining how to do certain skills. After watching the video I think that all of us will have a better sense of what we do while we are teaching and try to break any bad habits that we may have formed!
1 comment:
- Stephen Yang said...
You did do well given no time to prepare and you will improve greatly by the end of the semester. Looking forward to a great semester.
- January 25, 2009 at 1:51 PM
Subscribe to: Post Comments (Atom)


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I admit it's a stretch of the imagination, but I believe we'll be seeing more and more of this type of mumbo-jumbo in the future, as Progressives try to further dehumanize and desensitize citizens.
I myself am well over half Cherokee, and have a strong affinity for the earth and its creatures, but my beliefs are more those of a steward than of an "equal with Mother Earth".
I guess the UN would have people charged with capital murder for shooting a person, or willfully stepping on a beetle.............
From the Article below;
"....Bolivia will this month table a draft United Nations treaty giving "Mother Earth" the same rights as humans — having just passed a domestic law that does the same for bugs, trees and all other natural things in the South American country.
The bid aims to have the UN recognize the Earth as a living entity that humans have sought to "dominate and exploit" — to the point that the "well-being and existence of many beings" is now threatened......
Bolivia is a country with a large indigenous population, whose traditional belief systems took on greater resonance following the election of Morales, Latin America's first indigenous president...."


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Drum Roll Please................
Here it is! The first but not last contest here at Digging Up Your Roots!!!....and this contest is an easy one!!!...
I decided to make the prize for this contest to be Ontario, Canada related!
send an email to email@example.com (in the body of the email plz put in where you're from ex. Tilbury, Ontario, Warwickshire,England, Texas,U.S.A - this way I will have some idea as where I should base prizes on for future contests) I will reply to each email so you know for certain that you are entered.
I will draw one name from all who entered. Winner will be announced on Jan. 20 2005! I will email the winner to get shipping address.
Now here is the prize!!!
Roman Catholic Marriage Registers in Ontario 1828 - 1870 - Compiled by Renie A. Rumple
10 Map Set - Ontario Counties in 1852 by Thomas Maclear
a quick preview as to what is coming up tomorrow! I will posting my search for ODELL's in Warwickshire. What a hunt that has been!!
take care


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The mining, agriculture, and tourism industries are trying to recover from the effects of the epidemic
FREETOWN, Sierra Leone (Jan. 13, 2016) — Gold miner Dauda Kamanda has never been rich, but before Ebola hit Sierra Leone he was getting by selling the nuggets he unearthed to traders who exported them across Africa and the Middle East.
Then, one by one, his Lebanese and Senegalese clients in the northern district of Koinadugu fled as the deadly outbreak gripped the country in 2014, and Dauda's $500 (460-euro) monthly income disappeared.
"After the buyers fled, I had to take a part-time job carrying luggage at the lorry park for people going to the capital," he told AFP.
As the world awaits the announcement on Thursday, January 14, that the worst-ever Ebola epidemic has been beaten in west Africa, the 3 most affected countries of Liberia, Guinea, and Sierra Leone are taking grim stock of the devastation wrought on their economies.
The epidemic has devastated the mining, agriculture and tourism industries in the region – already fragile after years of civil war, dictatorship, and coups – where more than 11,000 people died from Ebola.
Strong recent expansion has been curtailed in Guinea and while Liberia has resumed growth, Sierra Leone is in a severe recession, according to the World Bank.
The bank estimates the regional economic damage to have been $2.2 billion over 2014-15 and has mobilized around $1.6 billion for Ebola response and recovery efforts.
Mine closures
Fueled by foreign investment in its mineral wealth, Sierra Leone had made considerable progress in recovering from a brutal 11-year civil war and its economy grew by 11.3% in 2013.
But Ebola slashed growth to 4% in 2014 and the economy contracted by a massive 21.5% in 2015, according to Finance and Economic Planning Minister Kaifala Marah.
"The traditional growth-driving sectors – agriculture, mining, et cetera – were severely disrupted," he told AFP, adding that the damage had been exacerbated by a slump in iron ore prices, the main international export.
Around 7,500 jobs were lost by the closure of two mines run by African Minerals and London Mining, which both went into administration.
A World Bank report released last June said employment had returned to pre-crisis levels, although employees were working fewer hours and earning smaller wages.
In Guinea, where small enterprises and the informal economy are heavily reliant on imports, the closing of air borders that accompanied the crisis were crippling.
"I often went to Dubai and Bangkok to buy gold chains and my shop was always well stocked," businessman Fatou Balde told AFP in Conakry.
"I had a lot of customers, especially among retailers, but now the shelves are empty."
Growth of 2.3% in 2013 slowed to 0.6% in 2014, although financial institutions expect the Guinean economy to expand by 4.3% in 2016.
In Liberia, 12% of businesses surveyed during the peak of the crisis have since closed down, according to the London-based International Growth Center (IGC).
Like numerous entrepreneurs interviewed by AFP, 45-year-old Amadou Diallo, who imports goods from Guinea to Liberia, said the closing of borders at the height of the crisis and an exodus of foreign investment had put him out of business.
"After the first outbreak we had to start over. It was hell really. We could no longer go for goods out of the country, we had to survive on the money we had," he said.
Reason for hope
The US Agency for International Development funded a mobile phone survey of 30,000 people across Liberia and Sierra Leone in the first 6 months of 2015 to find out the impact of Ebola on their finances.
In Sierra Leone 70% said their household incomes had dropped since June 2014 while the figure was 60% in Liberia.
Yet respondents were confident about job markets recovering, in a note of optimism echoed by ministers in Sierra Leone, who expect the economy to stabilize this year and recover strongly to 19.6% growth in 2017.
A further reason for hope, says Dianna Games of South African business consultancy Africa At Work, is the relative good health of the regional economy.
She noted in a recent commentary for the Johannesburg-based newspaper Business Day that growth for the broader Economic Community of West African States is forecast at 7% for 2016.
"Ebola's effect has been minimal because the 3 worst-affected countries comprise less than 2% of regional gross domestic product," she said.


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Was a bit hard to write for the past few days, although I did try for it. One of the hard things about it is making sure you write every single day, no matter what. It is difficult to know what excuses are invalid (almost all of them) and when you are just tormenting yourself by even trying.
I did end up writing a couple hundred words in the off time. I did sit most days. That is good.
When I first started exercising again, I used to bribe myself with the sauna: Okay, you have to go to the gym, but you don't have to exercise. You can just sit in the sauna. Once exercise became habit, I no longer need the bribe.
I need to figure out a writing bribe. The important thing is to work on it daily; the unimportant thing, for most of the time at least, is getting 2k words written. Eventually, you will just feel unmoored if you don't.
At least, that's what one hopes.


text: Find out which football teams are leading the pack or at the foot of the table in the Greek Superleague on BBC Sport. View the current Greek Super League standings, look back at previous seasons, on the official website of Super League Greece. Super League - Soccer Greece. SportStats offer Super League stats - Super League results, home/away standings and upcoming matches.


text:
My Chemical Romance - The Black Parade
View Single Post
November 23rd, 2006, 07:58 PM
New Member
Join Date: November 11, 2006
Location: England
Re: My Chemical Romance - The Black Parade
that's just like saying classical has changed, classical music is now Elvis. Emo died in the early 90's, this nu emo is actually pop punk
"we have living respiration, a breath echo vibration. solid sun inspiration and ground where forebears stood. I am here to see tomorrow. I am here to breathe today.
Words eye. Singularity. you did not sing and I would not dream. You are the shade breeze. you are the shade. you are the shade breeze blowing. the movers of the stream. Words eye. stops breath withholding the heart within its rib cage and it stops for a moment..."
Moss Icon


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I haven't updated my blog in some time because frankly, there is really nothing extraordinary to write about. I have been very busy with school, but that's mostly over with. I had been doubling up on classes so I can get done sooner and thankfully, last Thursday was my last week of doubling up. I have a little bit more free time now. I have one more week of my Wednesday night class and then I am on Christmas break for two weeks. After that, I return for my final class. Then my very long (69 days) break starts. I will have to go back to school about a month after our little bug is born, but I will be on maternity leave so hopefully, it won't be too terrible. My mother-in-law (I love her like my own mother) and my aunt have already lined themselves up to watch our little guy while I am in class.
Speaking of class, here is something funny that happened on Wednesday. Keep in mind I have had this professor for several weeks now.
I pulled an extra chair over to the desk so I could put my feet up. My back was bothering me and I wanted some extra support. My instructor says "What are you doing?". I told him that I was pulling a chair over to put my feet up. "How come? Is everything okay?". Sigh.
Yes, Mr. Professor. I am fine. I told him I was tired, pregnant and that my back hurt and I wanted to put my feet up.
"You're pregnant?!" I thought that was hysterical. How could he not tell? It looks like I have swallowed a basketball. I said "Did you think I was this fat normally?". The rest of the night, he kept saying "I didn't know she was pregnant" and he backtracked and said that he couldn't tell, blah blah. Too funny!
In baby news, I had my 31 week appointment yesterday. Can you believe it? 31 weeks! Crazy. Everything is fine. I haven't looked to see what my total weight gain is, but I have a feeling it's around 23 pounds. GULP!
Little man is moving around like crazy. Jason and I have taken to calling him The Goblin. It really fits. You know how goblins are short, slightly crazy and active? That's just like our Baby Walter (that is not his name FYI). I love feeling him kick and move around. Honestly, with the icky pregnancy I have had, that is the best part. I honestly think that is the only thing about pregnancy that I like. My belly moves all over the place and every once in a while, he will kick my so swiftly that it makes me gasp. I don't care. I love it. He can kick me in the ribs all he wants.
Now, Baby Walter is another of our nicknames. I picked that because I personally think that Walter is a completely ridiculous name for a baby. No offense to any Walters out there. Don't you have a hard time picturing an infant named Walter? It makes me giggle.
It's getting so close to Christmas and it seems this year has snuck up on me. Granted, I have had other things on my mind, but where has the time gone? I hope to get some neat Christmas pictures of me, Baby Walter, Jason and the Christmas tree to put on our New Year's cards. We do those every year rather than Christmas cards. Hopefully this pregnancy can inspire me to be creative.
Merry Christmas if I don't post again until afterwards!
And while this might be controversial, I don't care. If you could pray for Michelle Duggar and family, that would be wonderful. She delivered her 19th baby yesterday at 25 weeks. The tiny little baby is only 1 pound 6 ounces and babies that tiny have a lot of fighting ahead of them. God bless her and the entire family.


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Being able to have children could have an important positive effect on the future lives of pediatric cancer survivors. Working at a cancer institute makes us responsible for filling the gaps in our knowledge in this area of patient care.
We describe our activities in a series of young females diagnosed with cancer and evaluated for fertility preservation options. We discuss the developed skills and organization as well as the practical difficulties encountered in managing fertility preservation.
Since September 2012, laparoscopy and cryopreservation of cortical ovarian tissue has been performed in 16 girls (with ovary transposition in 3, and after several cycles of chemotherapy in 5) and egg banking in 4 young women (before chemotherapy in 2 and several years after treatment in 2).
Recommendations on fertility preservation indicate that discussing the problems early on is crucial to future success. It is unthinkable to simply provide information and offer the opportunity to choose a fertility preserving technique without helping and accompanying patients and their families in their decisions and choices on the matter.
Tumori 2016; 102(2): 174 - 177
Article Type: ORIGINAL RESEARCH ARTICLE
AuthorsMonica Terenziani, Cristina Meazza, Maura Massimino, Paola Viganò, Lorenza Gandola, Giorgia Mangili, Francesco Raspagliesi, Davide Biasoni, Marta Podda, Laura Veneroni, Francesca Filippi, Giovanna Riccipetitoni, Edgardo Somigliana
Article History
- • Accepted on 29/10/2015
- • Available online on 17/12/2015
- • Published in print on 18/04/2016
This article is available as full text PDF.
Established and experimental methods for preserving fertility have become available in recent years and cancer patients and their families show great interest in this topic (1). It has been reported that patients' concerns about their future fertility rank second only to questions about mortality (2, 3). Many articles have discussed the barriers encountered in efforts to deal with this issue, and the number of publications on the topic has increased in recent years (4, 5). Some approaches to fertility preservation may involve delaying a patient's treatment or the need for different professionals to work jointly on a patient's treatment plan (6).
Working at a cancer institute makes us responsible for filling the gaps in our knowledge in this area of patient care and drawing more attention to the growing importance of fertility preservation. In 2012 our institute started a cooperation scheme and developed a network with 2 fertility preserving departments offering oocyte cryopreservation. One of them was also equipped for processing and banking ovarian tissue.
In this report, we describe our activities for preserving fertility in children and adolescent females, the skills and organization that we have developed, and the practical difficulties encountered in managing fertility preservation.
A fertility professional (a gynecologist) was available once a week to assess inpatients and outpatients for the entire cancer institute. At our unit, the risk of infertility was always discussed with parents and patients (according to their age) when their informed consent was requested and before any treatment was started. Specific counseling with the fertility professional was suggested when the risk of infertility was considered high (i.e., in patients who were candidates for high-dose chemotherapy, pelvic radiotherapy, etc.) or at the parents' or patients' request.
Patient's age and pubertal status
In prepubertal children, the only option was ovarian tissue collection, and this was recommended based on the gonadotoxicity of the treatment. Depending on the girl's age, the procedure was performed by a pediatric surgeon or a gynecologist using a laparoscopic approach. The ovarian tissue was collected by a biologist from the laboratory and a pathology report confirming the absence of malignant cells detected by histology (7) was also produced. In postpubertal girls, the choice was between oocyte collection (a standard and effective procedure) and ovarian tissue collection (a promising option that is, however, still in the experimental stage(8)). It is worth adding that, in pediatric age, the type of disease cannot be influenced by hormonal stimulation, at least not as far as we currently know.
The question of timing
The usually rapid and symptomatic growth of pediatric malignancies does not allow us to delay the start of treatment for more than 7-10 days. Promptness and efficiency are crucial. This interval generally permits ovarian cortex banking, provided the network is fluent and efficient. Oocyte collection may require longer, even if the recent development of random-start protocols (to allow the immediate start of ovarian hyperstimulation) now allows to reduce the time of collection to less than 2 weeks in most cases (9). For this reason, the procedureis generally done in strict collaboration with the 2 fertility preserving centers belonging to our network. However, if the patient lives far away and referral to these 2 centers causes difficulties, the fertility professional handles the contact between the patient and fertility preserving centers closer to the patient's home.
General health status
In the case of patients with rapidly growing tumors and symptomatic disease, it is sometimes advisable to start chemotherapy immediately, postponing any fertility preserving procedures until 1 or 2 cycles of chemotherapy have shrunk the tumor and restored the patient to a better general health status. Even if the preferred approach in fertility preservation is to collect materials prior to starting cancer treatment, this cannot always be done in clinical practice. Although we realize that collecting materials after treatment is not optimal (10), the richness of the ovarian reserve in the age group considered may, however, allow this strategy.
The need for concomitant radiotherapy to the pelvic area has to be considered, as well as the need for chemotherapy. In patients prescribed radiotherapy to the pelvis, radiation oncologists estimate the treatment volumes and doses absorbed by the ovaries and uterus. If necessary, they might suggest transposing one or both ovaries outside the radiation field (11), in which case ovarian tissue can be collected as part of the same laparoscopic procedure. The risk of radiotherapy-related damage to the uterus and its consequences for a future pregnancy is also explained to and discussed with the family (12).
Informed consent and costs
Specific informed consent is needed for the laparoscopic procedure, for ovarian tissue harvesting or oocyte collection, and for the related processing and banking. Institutional review board approval (protocol Onco-Fertility) was obtained in January 2011.
In Italy, the costs of all these procedures are covered by the National Health System, except for the pathology report and an annual banking fee. The social worker at our unit can discuss these aspects with a view to partially or totally covering such costs with funds from charities if the patient's family is unable to do so. We have also begun to test the administration of gonadotropin-releasing hormone agonists prior to commencing chemotherapy in postpubertal girls receiving chemotherapy (13); in such cases, the drugs administered have so far been off label and the expense borne by the patients' families.
Posttreatment options
In patients who survived the cancer and who are 17-18 years of age or older, the fertility expert may be called in to assess their risk of premature ovarian failure, any uterine damage caused by radiotherapy, and/or any need for preventive oocyte collection. Given the above-mentioned richness of the ovarian reserve in our age group, one may indeed consider banking oocytes after the end of treatment if the ovarian reserve is not severely compromised. It is relevant to mention here that women in the western world tend to delay seeking pregnancy, and that the ovarian reserve may actually get exhausted in cancer survivors prior to allowing them to fulfill their reproductive wishes.
Psychological aspects
The multidisciplinary group should consider the favorable aspects but also emotional contraindications related to fertility preservation procedures. The maneuvers can be an implicit and important message of hope provided by physicians about the possibility of healing from cancer. But the proposal of an invasive procedure in addition to those necessary for cancer treatment can be experienced as an excessive burden by some young patients. Clinical experience has also shown the difficulty for some patients to think of a future pregnancy while they are in a phase of life and development in which such projects can be too early. At the same time, the scientific literature reports that the experience of not having been informed about the possibility to preserve fertility is accompanied by feelings of anger and depression (14).
The practical consideration of the high costs of such procedures for the National Health System also raises the question of justifying the choice of not offering them to patients with a poor prognosis. Still different is the problem in countries where the costs are sustained directly by the patient and the family. So the clinical, psychological, ethical and legal sense of a possible prognosis-related cutoff to decide whether or not to offer the preservation of fertility to a patient is something that remains to be defined.
Since September 2012, laparoscopy and cryopreservation of cortical ovarian tissue have been performed in 16 girls with the following diseases: Ewing family tumors (EW) (n = 5); medulloblastoma (n = 4); pineoblastoma (n = 1); Wilms' tumor (n = 1); non-Hodgkin lymphoma (n = 1); relapsing Hodgkin lymphoma (n = 2); relapsing CNS malignant germ cell tumor (n = 1); soft tissue sarcoma (n = 1). The girls were a median of 13.5 years of age (range 2-16 years). Three girls also underwent ovary transposition at the radiation oncologist's suggestion. All patients were able to begin their chemotherapy 2-4 days after the laparoscopic procedure. In 5 cases, ovarian tissue was collected after several cycles of chemotherapy had been administered.
Egg banking following ovarian hyperstimulation was performed in 2 patients, a 22-year-old woman with an ependymoma treated with radiotherapy only and a 24-year-old woman with EW. In the second case chemotherapy started with a 23-day delay, which is considered too long by our standards.
After consulting the fertility expert, 4 girls in our series refused any fertility preserving procedures (a 16-year-old girl with relapsing Hodgkin lymphoma and 3 young women including a medulloblastoma patient who already had a child, a patient with medulloblastoma in Turcot syndrome, and a patient with osteosarcoma and a family history suggestive of Li Fraumeni syndrome). In 2 other cases, a proposed fertility preserving procedure was shelved by the pediatric oncologist because of the risk of contamination by malignant cells; the patients were a girl with PNET whose disease subsequently progressed rapidly to the CNS, and a girl with metastatic Wilms' tumor and peritoneal and pelvic metastases.
Two 18-year-old girls were assessed some years after completing their treatment for medulloblastoma and synovial sarcoma secondary to Hodgkin's lymphoma, respectively. In both girls oocyte retrieval and cryopreservation were performed.
The iatrogenic sequelae of chemo- and radiotherapy in long-term cancer survivors are an emerging problem in pediatric oncology. Cancer treatments have improved considerably in recent years, giving pediatric cancer patients better chances of survival and consequently making it essential to try and assure these survivors a better future quality of life (2, 3). Being able to have children could have an important positive effect on their future lives, and may be seen as a confirmation for these young people that they are normal and healthy again. The risk of infertility is perceived as a big problem by young women and their parents. On the other hand, it is essential to bear in mind that the provision of fertility preserving options needs to be planned and organized; it is not a simple matter and it may meet with various difficulties. It is important to talk to patients and their families about the cancer diagnosis, the type of treatment needed, the cure rates achieved, the late effects of treatments, and the risk of inherited cancer syndrome in progeny (1); the risk of infertility is one of the issues to discuss.
Recommendations on fertility preservation indicate that discussing the problems early on is crucial to future reproductive success (15-16-17). But this is still only the starting point (18). In our opinion, it is unthinkable to simply provide information and offer the opportunity to choose a fertility preserving technique without accompanying families in their decisions on the matter and guiding them along a properly encoded path. Pediatric oncologists have to decide how much time there is to spare before starting chemotherapy, or whether it is better to delay ovarian tissue or oocyte harvesting until after the patient has had chemotherapy. Radiation oncologists must identify the radiation target volume early on and consult gynecologists on where best to transpose an ovary, if necessary. Then it is up to the fertility professional to choose the best method for a given patient at a given time. For all these aspects to be handled adequately, it is fundamentally important to have a motivated team of specialists with good communication and capable of working together toward the same goal, which is ultimately to give patients the best chances of being cured of their cancer with the least possible iatrogenic sequelae.
Such teams do not develop spontaneously; they have to be nurtured and motivated, primarily by the physicians involved. Multidisciplinary care requires close communication and high levels of up-to-date professional expertise, and it is time-consuming because every single patient needs to be discussed in depth. This area is challenging and rapidly mutable since fertility preservation is a work-in-progress area. However, it has to be faced now (19). We cannot wait for established conclusions since this will take decades from now, in particular in pediatric patients.
Quinn GP Murphy D Wang H Sawczyn KK Knapp C Having cancer does not change wanting a baby: healthy adolescent girls' perceptions of cancer-related infertility. 2013 52 2 164 169
Letourneau JM Ebbel EE Katz PP et al. Pretreatment fertility counseling and fertility preservation improve quality of life in reproductive age women with cancer. 2012 118 6 1710 1717
Kenney LB Cohen LE Shnorhavorian M et al. Male reproductive health after childhood, adolescent, and young adult cancers: a report from the Children's Oncology Group. 2012 30 27 3408 3416
Letourneau JM Smith JF Ebbel EE et al. Racial, socioeconomic, and demographic disparities in access to fertility preservation in young women diagnosed with cancer. 2012 118 18 4579 4588
Adams E Hill E Watson E Fertility preservation in cancer survivors: a national survey of oncologists' current knowledge, practice and attitudes. 2013 108 8 1602 1615
Terenziani M Spinelli M Jankovic M et al; PanCare Network. Practices of pediatric oncology and hematology providers regarding fertility issues: a European survey. 2014 61 11 2054 2058
Greve T Wielenga VT Grauslund M et al. Ovarian tissue cryopreserved for fertility preservation from patients with Ewing or other sarcomas appear to have no tumour cell contamination. 2013 49 8 1932 1938
Loren AW Mangu PB Beck LN et al; American Society of Clinical Oncology. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. 2013 31 19 2500 2510
Cakmak H Katz A Cedars MI Rosen MP Effective method for emergency fertility preservation: random-start controlled ovarian stimulation. 2013 100 6 1673 1680
Biasin E Salvagno F Berger M et al. Ovarian tissue cryopreservation in girls undergoing haematopoietic stem cell transplant: experience of a single centre. 2015 50 9 1206 1211
Terenziani M Piva L Meazza C Gandola L Cefalo G Merola M Oophoropexy: a relevant role in preservation of ovarian function after pelvic irradiation. 2009 91 3 935.e15 935.e16
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- Terenziani, Monica [PubMed] [Google Scholar] 1, * Corresponding Author (firstname.lastname@example.com)
- Meazza, Cristina [PubMed] [Google Scholar] 1
- Massimino, Maura [PubMed] [Google Scholar] 1
- Viganò, Paola [PubMed] [Google Scholar] 2
- Gandola, Lorenza [PubMed] [Google Scholar] 3
- Mangili, Giorgia [PubMed] [Google Scholar] 2
- Raspagliesi, Francesco [PubMed] [Google Scholar] 4
- Biasoni, Davide [PubMed] [Google Scholar] 5
- Podda, Marta [PubMed] [Google Scholar] 1
- Veneroni, Laura [PubMed] [Google Scholar] 1
- Filippi, Francesca [PubMed] [Google Scholar] 6
- Riccipetitoni, Giovanna [PubMed] [Google Scholar] 7
- Somigliana, Edgardo [PubMed] [Google Scholar] 6
Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy
Obstetrics and Gynecology Unit, San Raffaele Hospital, Milan - Italy
Pediatric Radiotherapy Unit, Fondazione IRCCS Istituto Nazionale dei Tumori , Milan - Italy
Gynecology Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy
Pediatric Surgery Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy
Infertility Unit, Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan - Italy
Pediatric Surgery, Ospedale dei Bambini V. Buzzi, Milan - Italy
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Hooray for DeviantArt, source of all the best cosplay. This cosplay, of one of the Shiva Sisters, is downright upsetting, but that's what it's supposed to be. It's not supposed to give you a… you know. Anyway, here you are:
This is shiva
Not some freaky robot transformer that turns into a motorbike !
Square Enix, what have you done !
May not like the game, but have to give points for the talent and effort that went into that.