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Dr. Stephen Vanner Receives CIHR Grant Novel signaling mechanisms leading to pain in irritable bowel syndromePublished Fri Jun 23rd 2017
Congratulations are extended to Dr. Stephen Vanner upon receipt of a CIHR grant entitled "Novel signalling mechanisms leading to pain in irritable bowel syndrome". Below you will find an abstract providing additional information on this cutting edge research.
The abstract below explains the research being conducted by Dr. Vanner.
Irritable bowel syndrome (IBS) is characterized by abdominal pain and altered bowel habits. It is extremely common, affecting over 10% of the adult population in North America and exerts a tremendous societal impact. For example, it is among the most common reasons for workplace absenteeism and in Canada, costs over $1B annually for diagnosis alone.
Despite this, the mechanisms that underlie IBS remain poorly understood and as a result, the available treatments are not very effective. The most debilitating symptom is abdominal pain, and we have evidence that inflammatory mediators in the gut, known as proteases, can activate pain-sensing nerves in the gut and intensify the IBS patient's pain.
Our previous studies and preliminary data have revealed that:
1) In IBS patients, multiple proteases are released and trigger sustained activation of pain-sensing visceral nerves;
2) Changing the diet of IBS patients can alter the activation of inflammatory cells called mast cells (an important source of gut proteases);
3) In germ-free mice inoculated with the microbiome of IBS patients, we can recapitulate the increased pain signaling and protease activity when we feed these mice diets comparable to those in humans.
Based on these findings, we believe that multiple proteases lead to sustained pain signalling in IBS and that dietary factors sustain this abnormal neuronal activation. Using human biopsies in animal IBS models, we will define the protease profile released in response to changes in diet, and examine if the microbiome of a given patient influences the degree of protease-induced pain. We will also investigate how these proteases, once triggered, can sustain excitation of gut pain-sensing nerves and determine whether protease singling is amplified by other mast cell mediators, such as histamine.
Together, our work will clarify how proteases trigger and prolong pain signaling and in doing so, identify novel targets for treating IBS pain.


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Dendritic cells (DCs) are the most potent type of antigen-presenting cells controlling both innate and adaptive immune responses. DCs are continually differentiated from hematopoietic progenitors, ensuring that self versus non-self discrimination is maintained in the steady-state and during immunological challenges. However, how DCs are developed at the molecular level remains incompletely understood. MicroRNAs (miRNAs) have emerged as one of the critical regulatory molecules in development, cell proliferation, differentiation and tumorigenesis. Our long-term goal is to identify specific miRNAs and define their roles in DC development and function. The objective of this project is to determine whether specific miRNAs are critical in human monocyte-derived DC differentiation and function. Our hypothesis is that the process of monocyte differentiation into distinct immature and mature DCs and the immunological functions of differentiated cells are regulated by specific miRNAs.
In Aim 1, we will identify and validate the target genes regulated by a specific miRNA that is highly up-regulated in both immature and mature DCs. Our preliminary data suggest that this miRNA may play a role in modulating DC apoptosis through a feedback mechanism. To identify the miRNA targets, we will perform an mRNA expression microarray using RNA from immature DCs that are either over- expressing or have this miRNA expression silenced. Expression of mRNA will be profiled in both experiments, and the intersected mRNA that are decreased and increased will be identified. Molecular validation assays (a luciferase reporter assay, qPCR, Northern and Western blot) and DC apoptosis analysis after knocking down or over-expressing the candidate gene will be carried out.
In Aim 2, we will evaluate the impact of altered expression of three specific miRNAs on human DC development and function in vitro. Our preliminary data demonstrate that expression of these miRNAs is significantly altered during DC development. To address this question, silencing or over-expressing these miRNAs will be performed in monocytes and DCs. The effects of altering these miRNA expression levels on DC development, maturation and physiological functions will be analyzed using both molecular and immunological assays. The proposed research is innovative and significant because the role of miRNA in DC development and function remains unexplored. New target genes that are differentially regulated by miRNAs during DC development will be identified. Our work also has translational relevance, as there is a great deal of interest in developing clinical applications using miRNAs to modulate DC development and functions in a broad spectrum of diseases including infections, autoimmunity, cancer, transplantation-related graft versus host disease, and graft rejection
Our research will identify novel small RNA molecules that regulate the development and function of human dendritic cells, the most potent type of white blood cells that keep the immune system in balance. Our research may lead to the development of new small molecules to modulate dendritic cell development and function in infection, allergy, cancer, autoimmunity, and transplantation.
|Park, Haein; Huang, Xin; Lu, Changming et al. (2015) MicroRNA-146a and microRNA-146b regulate human dendritic cell apoptosis and cytokine production by targeting TRAF6 and IRAK1 proteins. J Biol Chem 290:2831-41
|Huang, Xin; Park, Haein; Greene, Joseph et al. (2015) IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas. PLoS One 10:e0133152
|Lu, Changming; Chen, Jianfeng; Xu, Hua-Guo et al. (2014) MIR106B and MIR93 prevent removal of bacteria from epithelial cells by disrupting ATG16L1-mediated autophagy. Gastroenterology 146:188-99

subset: commoncrawl


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Oil and gas business is always a demanding sector where cost is a very critical factor. Price fluctuations can impact not only the company, but entire economies.Read more
Month: April 2017
Running A LIVE Supply Chain With Real Time Data!
What is supply chain management (SCM)? According to Wikipedia – "Supply-chain management has been defined asRead more
Drive Your Marketing Effort In The Right Direction With Data Analytics!
It is a fact that to have a flourishing business, you should be able to analyze the available data. For exampleRead more
How Using A Single System Helps A Growing Businesses?
Is it possible to get one single tool that can manage all your business? Can that tool cover all the core business operations, giving you fullRead more
2 Effective Uses of Business Intelligence Tool to Improve Sales
Sales and marketing are the two important pillars of any company. If these two teams get the facility of working on interactive dashboards thatRead more
Significance of Aging Reports in SAP Business One
The very first question comes in mind is - what is an aging report? Well, per www.answers.com – "Accounts Receivable Aging ReportRead more
Top 10 reasons you should fall in love with Power BI
Are you thinking that what's good about Power BI? Some of us do not fully understand what Power BI is and why it is unique in the world of Business IntelligenceRead more
Continuous Accounting: Does it Matter to Your Business?
Traditional accounting that is being followed from eons is when you wait for the financial year to get over, then work long hoursRead more
Is Inventory Management The Most Challenging Aspect Of Your Business?
Inventory management is considered a thorn in the flesh for any business, which needs to store goods for any period.Read more


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|Demographics of Basti
According to the 2011 census Basti district has a population of 2,461,056, This gives it a ranking of 179th in India (out of a total of 640). The district has a population density of 916 inhabitants per square kilometer (2,370 /sq mi) . Its population growth rate over the decade 2001-2011 was 18.05 %. Basti has a sex ratio of 959 females for every 1000 males, and a literacy rate of 69.69 %.
As of 2011 India census, Basti has a population of 24,61,056. Males constitute 12,56,158 that is 51.04% of the population and females 12,04,898 that is 48.96%. Percentage decadel growth of population in Basti is just 18.04% from the year 2001. Sex ratio of Basti is 959 which is better than the national sex ratio of 940.27. It is also better than Uttar Pradesh`s sex ratio of merely 908. Child Sex ratio of Basti is 922 which is again better than the national average child sex ratio of just 914 female child. Basti has an average literacy rate of 69.69% which is higher than the literacy rate of Uttar Pradesh 69.72%.Although it is less than the national average literacy rate of 74.04% Male literacy is 80.65%, and female literacy is 58.35%. Population density per km2. in Basti is 916.


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Criminal – Review
Criminal Review:
The only reason some action and thriller lovers might find their way into a theatre this weekend to catch 'Criminal' is because of the hyped up trailers and shiny cast that came together to make this supposed crackerjack. It might even be because of Ariel Vromen's previously well received 'The Iceman' that got people interested in it. Reconsidering this movie should be in your best interest, as you might want to ease back and watch something that values your money and is worth your time like 'The Jungle Book' and maybe even SRK's 'Fan'.
Criminal's storyline centers itself around CIA agent Bill Pope who is out on a quest to pay ransom money to a hacker who calls himself The Dutchman and is killed while on the job. To keep his mission under way, the CIA steps in to fuel Dr Frank, a neurosurgeon's experimental work of transferring a person's sub-conscience into another person's mind. They bring in a convict Jericho Stewart, who is seemingly the only suitably candidate, to help them uncover the location of the Dutchman and prevent the launch codes that he possesses from getting into the wrong hands.
While it's true, an action thriller usually thrives to thrill with thrilling action sequences, this movie is one of those that makes little room for practicality. Dr Frank's procedure of conscience-transferring concludes as fast as a kid eating a bag of Doritos. Adding on, Ryan Reynold's Bill Pope is presumedly the star of the movie whose winning personality is that which was intended to be passed on to Kevin Costner's Jericho Stewart, seems to have been lost right after his death in the first ten minutes. As Jericho's mind is infected with the former CIA agent's memories, he plays them out to his benefit but seems to find a deeper meaning to his life in the process.
The movie delivers just what you probably expected: loud explosions, poor acting and an overly boring storyline that will probably fill your ears with loud yawns from both sides of your seat. Kevin Costner is one of Hollywood's most renowned actors, and yet fails to captivate us, by portraying a convict whose personality fits Christopher Nolan's runaway and irritable Bruce Wayne or a more insane version of American History X's Derek Vineyard. Implanted with memories that contradict his own, it is difficult to engage with his better nature, as he struggles to convince us while struggling to convince himself at the same time. His actions do speak louder than his words, as he manages to beat and punch his way through every sane conversation that comes his way.
Movies with a fairly grand spectacle are usually meant to draw audiences by their action sequences regardless of whether it has a weak storyline to set all of it in place. Sadly, whether you are sitting in front or at the back of the theatre, your eyes will painfully adjust to the loud smashing of cars and bothersome fights that originate without any meaning. As far as humor goes, you find yourself laughing at the movie instead of with it. Along with that, Jericho's actions that keep him moving raise too many questions. You can even find yourself doubting the movie's representation of the police and CIA as they seem to be quite negligent and dim-witted about their surroundings. It mostly carries way too many questions rather than answers, and consists of more plot and loop holes than a straight forward story about good and evil and the outcome whether it's good or bad.
Agonizing as it seems, the movie also lacks talent from the talented cast it boasts, only because they can't find their place in a plot that is too thick to perceive. Little can be said about them which includes Tommy Lee Jones as Dr. Franks and Gary Oldman as Quaker Wells, the CIA who do nothing but manage to decorate the movie, like lights on a dead christmas tree. The only good thing you can hope to catch is Pope's wife, played by Gal Gadot who appears a couple of times, and who manages to soften this patchy and brain aching movie lovable smiles and soft eyes as she grieves her husband's death. Other performances from Alice Eve and Jordi Molla are not even recognizable as they just come and go without anyone realizing. You would think such A list stars would bring big bucks to this movie's pockets, but you're quite wrong as it is quite the opposite that we witness how poorly the movie values them by striking them off in ways a movie goer wouldn't observe, right before they make a mark as their characters.
Ariel Vromen has managed to come off as the real criminal over here who sacrifices more than his head but the heads of every talented person attached to this movie by blowing them all up onscreen. It is a film that needs more heat than it deserves which manages to convict its heroes and villains for merely being involved with this appalling movie, it's poorly conceived storytelling skills, redundant conversations and a lack of understanding of the concept of a thrilling action film. Although this fizzle of a thriller does one thing right: its ability to help you pass the time on one of those monotonous days where you're waiting for it to come to an end. Catch 'Criminal' this weekend, if you dare.
Read Similar Articles?…
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Alston Rodrigues
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From the 1st September 2016 all new Home Care Packages approved by the HSE will be provided by organisations that have been approved by the HSE following a detailed tender process.
The 32 approved providers, appointed under the 2016 tender process meet a required level of national standards. However it is important to note that existing providers also provide a quality service work under agreed standards, which are monitored by staff in the local health office.
Each of the 9 Community Health Organisations across the country have a number of approved providers available to provide service to clients locally where the HSE is not in a position to provide the service directly. The new arrangements apply only to clients whose Home Care Package is approved from the 1st September 2016. Arrangements for clients currently receiving home care services will not be affected.
A home care package may be approved following a care needs assessment by a local health professional. Clients choose their service provider from the list of approved providers in their area and the HSE advises clients to include a number of choices should their first choice not be in a position to deliver the service
Find an approved provider in your area
CHO 1 – Cavan/Monaghan, Donegal, Sligo/Leitrim
CHO 2 - Galway. Mayo, Roscommon
CHO 3 - Clare, Limerick, North Tipperary
CHO 4 - Cork & Kerry
CHO 5 - Carlow/Kilkenny, Tipperary SR, Waterford, Wexford
CHO 6 - Dublin South East, Dun Laoghaire, Wicklow
CHO 7 - Dublin South City, Dublin West, Dublin South West, Kildare, West Wicklow
CHO 8 - Laois/Offaly, Longford/Westmeath, Louth, Meath
CHO 9 - Dublin North Central, Dublin North West, Dublin North
Information on how to access a home care package
Application form
Information booklet.
Can't find what you're looking for? Call us on 1850 24 1850


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Latest Announcements
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|TV Shows you enjoyed in the 1980's and 1990's
|Tweet Topic Started: Jun 30 2014, 09:14 AM (152 Views)
|Julius Quasar
|Jun 30 2014, 09:14 AM Post #1
CDF Commander of the Army
This is an example of what shows were on then, you know, back when kid's shows were actually awesome:
We need not discuss just these shows alone from that era, we can talk about any of them, so feel free to bring up or even post a video like this here.
Now, a few modern kid's shows like Transformers: Prime or Dan Vs. are still cool, but they were cancelled after 3 years. Sad. But we'll always have the memories of our favorite kids' shows.
I remember some of these shows in particular, but not all of them. I remembered enjoying Heathcliff, Transformers G1, JEM and the Holograms, TMNT, G.I. Joe, Uncanny X-men, Dennis the Menace, the Smurfs, Muppet Babies, Rainbow Brite, the original My Little Pony, Ghost Busters, Strawberry Shortcake, and so many others...
|Julius Quasar
|Jun 30 2014, 01:23 PM Post #2
CDF Commander of the Army
I wasn't allowed to watch much TV growing up, my stupid parents constantly dragged me off to Cub Scouts, sports, and other dumb places and events I didn't want to go to. But I got in as much TV watching as I could.
I also liked Captain Bucky O' Hare...Captain N...
|1 user reading this topic (1 Guest and 0 Anonymous)
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|12:25 AM Aug 17


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The ClearConcepts 4 Step Approach To Problems
The JEE and the AIPMT exams are highly competitive exams.
Around 2% of all candidates appearing for JEE get selected for admission into the IITs. The success rate (among all students appearing) is marginally higher for admission into the NITs.
The AIPMT exam for admission to medical colleges across India has a much higher success rate but, at 6.5%, it is still an extremely competitive examination.
Therefore, to succeed at such examinations, you need to be methodical in your approach to applying concepts.
The ClearConcepts methodology is a tried and tested methodology which, if applied properly, will enable you to improve your chances of success considerably. We outline it below for your benefit.
Step 1 :
Understand The Problem
- Write down what you have been given (Call it inputs if you will)
- Write down what you have to find out (Call this the output from the input)
- If you see inconsistent units, the unit conversion should be done here itself.
- State all the values of constants and assignation of variables.
- Any figures that depict the problem should also be included here for, if a problem requires visualization in order to be solved, then one cannot proceed with a solution until the problem is clearly visualized.
Step 2 :
Plan Your Approach
- In this step, you describe the path to be taken to solve the question
- It includes any formulae / law / theorems / reaction mechnisms / special properties that will play a role in the solution
- For some problems this may be a single line like "We will use Newton's law of gravitation to determine the force between the two bodies".
- For others, this step can be quite extensive.
Step 3 :
Carry out your Plan
- This step is the actual 'number crunching' where you work out step 2.
- The length of this will depend on
- how easy or difficult the mathematical simplification is
- how many stages a reaction might involve
- on the number of concepts that the solution requires (obviously)
Step 4 :
Look Back
- This is where you actually check your working to see if what you have obtained as a solution is reasonable
- If you haven't reached one of the four alternatives, it isn't reasonable!
- You also need to check that your working in step 3 is correct.
- If not, you may have reached the wrong alternative
- It is important to understand that errors can happen in any (and possibly all) of the first three steps.
- Step 1 Errors
- You could have visualized the problem incorrectly
- or failed to convert units
- or misread a word
- or misunderstood what the question is asking for.
- Step 2 Errors
- You may be using a theorem where it is not applicable
- You may have remembered a formula incorrectly
- or used an inapplicable reaction or reaction mechanism
- or have reached some conclusion about a 'property' that really is not justified.
- Step 3 Errors
- You could have done the mathematical manipulations incorrectly
- or missed a stage in a series of reactions.
- Step 1 Errors
- In short, step 4 is a review process which you must drill yourself to undertake even if you have arrived at one of the four alternatives
To summarize, the methodology involves
- Putting down what is given and what is desired (Aim and Apparatus in terms of laboratory terminology)
- What your methodology is going to be (Procedure)
- Working out basis the methodology (Following Procedure)
- Reviewing your answer (Observations and Conclusions)
In theory, this is a very simple process.
The Four Step Method in Practice
ClearConcepts has been using this method to teach its students for the past 5 years.
In our experience, most of the errors occurred in Steps 1 and 2.
For most problems there is not more than one way to solve it. For the tougher problems too, there are only a handful of approaches that can be used. But there are numerous ways of going wrong depending on the misunderstandings specific to the student.
The ClearConcepts Methodology inculcates in students the discipline of adopting this method through its 'Online Forum' where students can raise their doubts about any problem they are solving and where the teachers interact with the student to clarify the student's own misconceptions.
For it to be successfully used, students have to assimilate this process into themselves as their approach to solving every problem till it becomes 'muscle memory'
Once you do this, we promise you that you will be amazed at your results.
To see this methodology applied to the IIT JEE 2015 Mains Exam click here


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This article, Land of Rain, is property of Ten Tailed Fox.
Description and History
The Land of Rain (雨の国, Ame no Kuni) is home to Amegakure, and is filled with a great number of small buildings in a heavily wooded area, suggesting that it might perhaps be located in a rainforest. Its borders are highly defended, and those wishing to pass through the country must first give their name, purpose, and amount of time they intend on staying in the country before being allowed admission. Even if one is permitted to enter the country, they will be under constant surveillance by the government for the duration of their stay.
Because the Land of Rain is situated between three of the five great countries, it often acts as the battlefield for their wars. As a result, its government lacks stability and much of its population is composed of refugees from the various wars. Unknown to the rest of the Naruto world, apart from Konoha, the country has been in a civil war for an undisclosed amount of time, which only ended after the Akatsuki leader, Pain, overthrew the entire country singled-handedly. In doing this, he has become not only the village Leader of Amegakure, but the Daimyo of the Land of Rain itself.


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Alzheimer's disease is a progressive brain disorder that destroys brain cells leading to a steady decline in memory, mental capability and the ability to perform the usual activities of daily living. Alzheimer's disease has no cure. People with Alzheimer's disease can live for many years after losing the ability to perform even simple daily tasks. They require a great deal of attention and help from caregivers who, most often, are family members, relatives and friends.
Alzheimer's disease is the 6th leading cause of death among all ages in the United States. According to the Alzheimer's Association, roughly 5.2 million Americans have this disease or some other form of dementia. This number will rise to almost 23.8 million by 2050, as the boomer population ages.
Alzheimer's is a major drag on state and federal budgets, not to mention families. The annual cost of Alzheimer's is expected to reach $1 trillion a year by mid-century, according to the Alzheimer's Association.
Medicare and Medicaid often fall short in the face of the overwhelming costs associated with the disease. Much of the burden of care-giving falls on families. About 147,000 unpaid caregivers in Maine tend to loved ones with Alzheimer's and dementia, care whose value is estimated at more than $900 million.
Maine has a growing problem with Alzheimer's disease. According to newly released statistics, the number of Mainers living with Alzheimer's disease will rise from 37,000 in 2013 to over 53,000 by 2020. Maine has the oldest population in the country and large rural areas with limited or no access to services.
Mainers have taken action to address this problem. In March 2013 Maine announced the first-ever state plan for Alzheimer's disease. This plan follows the release of a national Alzheimer's disease plan in May 2012. The plan in Maine calls for raising awareness about Alzheimer's disease, providing better diagnosis and treatment, offering support to caregivers and, in general, improving the quality of long-term care services for Alzheimer's disease.
The state plan has a goal of making Alzheimer's disease a top priority in Maine with state agencies, local businesses, philanthropic groups and the private sector. The state plan also seeks to raise general awareness regarding what needs to be done to address the problems associated with Alzheimer's disease.
The Maine Chapter of the Alzheimer's Association was incorporated in 1987 and offers multiple resources for families dealing with a loved one suffering from Alzheimer's disease. These resources include information concerning:
Support Groups Education and Programming Professional Care Providers Professional Training Local News Volunteer Opportunities
You can contact the Maine Chapter at its 24/7 Helpline 1-800-272-3900 or visit their website.
Photo Credit: Taliesin, Morguefile.com


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NOTE: On September 18, Keeping your Balance CEO Becky Brown spoke at the San Francisco Small Business Expo in Fort Mason on the topic of the "Top 5 Reasons to Outsource Your Accounting. Today's post is a summary of her presentation.
Small business owners have a lot to think about: sales, staffing, customer service, vision, growth, etc. Perhaps the one responsibility they'd rather not think about is accounting.
Some business owners try to avoid the hassles of accounting by simply ignoring the problem. "I'm too busy," they say, but no business can hide from accounting. If the tax penalties for poorly done or completely not done tax returns aren't motivating enough, hopefully the knowledge that you have basically no visibility into the vital indicators of business health will be.
Sure, there are online tools out there to make the process less burdensome, but even "automated tools" require extensive data input and difficult judgment calls. And while you might think that a part-time bookkeeper might solve your problem, it really depends on your needs, and there are downsides there too.
Here are the Top 5 Reasons to Outsource Your Accounting
1) Focus on Growth
This may seem obvious to some, but every minute you spend on your books is a minute you aren't growing your business. There are plenty of accountants and bookkeepers out there who can do your books better and more efficiently than you, but no one can grow your company better that you can. So, while you focus on growing, selling, hiring and raising more money, your outsourced accounting team can handle all of your Invoicing (A/R), billing (A/P), manage your vendor relationships, issue your financial statements.
2) Generate More Revenue
Inefficient internal bookkeeping processes can be a time waster for everybody in your organization, and time wasted is time not spent building revenue. Your outsourced accounting team will set up new efficiencies to reduce the number of touch points with each accounting item (check, invoice, bill, etc.) and allow your entire team to spend more time performing revenue generating activities.
3) Enjoy the Power of Teams
Individual full-time or part-time bookkeepers can be great assets to a company, but they can also be a liability. It's never good to have such important information and processes handled by one person. Working with an outsourced accounting team, you are protected against the risk that your bookkeeper may move, quit, go on vacation, get hit by a bus, or get (gasp!)…pregnant.
4) Access to Best in Class Software
Choosing the right invoicing, time tracking, expense reporting or payroll software can be arduous. So, stop doing it! Your outsourced accounting team is in the business of knowing all about the best technology solutions to streamline your internal processes.
5) Grow with Confidence
Small businesses have a funny habit of growing very quickly. We know it's a fancy problem to have, but it can be a real hassle if your accounting team can't scale quickly with you. Outsourced accounting departments are infinitely scalable and will assign new bookkeepers to your account on an as needed basis to grow with you.
Is Outsourced Accounting Right for You?
In many ways, outsourced accounting is right for any sized company, but over the years we've developed a simple recipe for the "sweet spot" for companies to make the transition to outsourced accounting:
- Planning to have more than $500k in revenue within a year or two
- Multiple revenue streams or locations
- Intense interest in rapid growth
If you'd like to discuss if outsourced booking is right for your start-up, small business, or firm, drop us a line at 415-399-9844 or firstname.lastname@example.com.


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Check out some samples or get an intro to our creative services.
Just wrapped editorial on The History Channel's new documentary special "Up in Arms: The History of the Second Amendment" for Left/Right productions which will be airing on the History channel this spring.
Wrapped Keeping it Real (Estate)– the new Bravo real estate show featuring Bethenny Frankel & Frederik from Million Dollar listing.
Update– they changed the name to Bethany and Frederik
Check it out on Bravo, Tuesdays at 10pm.
Did some work on season 8 of Real Housewives of New Jersey.
Posted several Brand Education videos for the following whiskey brands:
Knob Creek, Auchentoshan, Bowmore, and Kilbeggan.
Did some work for NBC Sports / Adidas — A "Men in Blazers" episode profiling a young soccer player from Ghana overcoming incredible obstacles. You can check it out here.
Currently in Post on Teen Mom: NJ, the newest iteration of the MTV's most highest-rated show.


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Shop By Collection
Shop By Fragrance Family
Bath and Body
Home Fragrance
Gift Ideas
Discover Thymes
By popular demand, here's an ideal way to sample Thymes best-selling fragrances, so you can buy with confidence. Contains samples of our collections' most popular items: body lotions.
A soft breeze brings springtime sweetness through delicate hints of jasmine, with nuances of hyacinth, lily of the valley, orange blossom and raspberry that fills the air. It's nature's expression marking the start of something new and beautiful, creating a fragrant canvas indoors.
Pure water lily. Dewy white cyclamen. Crisp driftwood. Tart yuzu. Brilliant lemon pulp. Intriguing bamboo.
We are required by law to collect state sales tax on orders being shipped to
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For more shipping information, visit our shipping page.


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Boston MA Area Featured Properties
Scroll down to find stunning real estate for sale in the Boston, MA area. Look through a variety of listings, including luxury homes, townhouses, condos, rentals, and land for $2 million and up. In this search, you can dream big: find your next historic estate with gardens, water features and a guest house, or let a modern condo with views of the Charles River catch your eye.
Found something you love? Save your favorite listings when you create an account with our site, and you can get email updates when new properties match your criteria. For more information and to schedule a showing, contact us!


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On July 11, Dallas Police Chief David Brown criticized law-abiding citizens with rifles who attended the July 7 Black Lives Matter rally — although good guys weren't the ones shooting at police officers.
Brown said, "There's been a presumption that a 'good guy with a gun' is the best way to resolve some of these things. Well, we don't know who the good guy is versus who the bad guy is if everybody starts shooting."
DeadState.org gleefully seized on his statement in a piece titled, "Dallas police chief slams NRA's 'Good Guy With a Gun' Theory."
But the open carry of rifles has been legal in Texas for decades. Not days, not weeks, not years, but decades — so why is it only now a problem? Moreover, "good guys with guns" were not the ones shooting at police officers. The "bad guy with the gun" was doing that — and he clearly differentiated himself from the good guys by doing it.
Does that mean there will not be moments when officers have to approach law-abiding citizens openly carrying long guns and ascertain their intent? No. It does not rule that out.
In fact, we saw that very scenario play out on July 7, when an officer approached black gun rights activist Mark Hughes and asked for his rifle, which Hughes handed over before being taken to police headquarters to be questioned and released.
Video posted by A.D. Samuels captured Hughes' interaction with the police officer. It shows that his demeanor was one of cooperation and respect — the complete opposite of what was demonstrated by the gunman who was focused on "killing white officers."
To put it plainly, the differences between good guys with guns and bad guys with guns is not subtle.
And the NRA's "good guy with a gun" theory — officially given voice by Wayne LaPierre in December 2012 after the heinous attack on Sandy Hook Elementary — is much older than 2012. In fact, it is much older than the NRA. It is as old as man himself, representing an intersection of common sense and natural law.
Thomas Jefferson voiced that same theory when he said, "The laws that forbid the carrying of arms disarm only those who are neither inclined, nor determined to commit crimes."
In other words, laws that disarm "good guys" with guns only succeed in taking away the guns of those who never would have used them for harm to begin with.
AWR Hawkins is the Second Amendment columnist for Breitbart News and political analyst for Armed American Radio. Follow him on Twitter: @AWRHawkins. Reach him directly at email@example.com.


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Istanbul Travel
Tour Details
Istanbul Travel
Istanbul is hot. And we're not talking about the weather. These days, there are more happening restaurants, bars, galleries and clubs around town than there are exquisite Ottoman mosques (and that's a lot). The international fashion and design press have been talking up İstanbul ad nauseam, but the most significant thing about the accolade 'World's Hippest City' is that İstanbullus themselves have come believe it. The creeping sense of decrepitude that had fallen like a pall over their once-all-powerful home town has vanished, replaced by a sense of energy and innovation not seen since the days of Süleyman the Magnificent.
The city's over-abundance of important historic buildings and exciting new art galleries and museums provides visitors with more than enough to see during the day, but it's at night that the place swings into high-velocity, mega-stylish action. Locals are flocking to see and be seen at an ever-growing array of bars, clubs and restaurants, bringing with them an infectious sense of joie de vivre and a discerning ability to judge these places on their standard of service, drinks, music and food as well as their position in the what's-hot-and-what's-not stakes.
That's not to say that the locals are turning their backs on much-loved city institutions such as the rakı-soaked meyhane (tavern) or tranquil çay bahçesi (tea garden), because they wouldn't dream of doing anything so foolish. They know, after all, that such institutions are one of the reasons that their home is – and always has been – rightfully dubbed the 'City of the World's Desire'.
The most popular way to explore the Bosphorus is by ferry. The boats fill up early in summer – especially on weekends – so buy your ticket and walk aboard at least 45 minutes (preferably an hour) prior to departure to get a seat outside or next to a window. During the trip waiters will offer you fresh orange juice, tea and other drinks.
Most day-trippers take the ferry all the way to Anadolu Kavağı, stopping at various sights along the way, but some go only as far as Sarıyer, on the European shore. They then make their way back to the city on the bus, stopping at Emirgan and Rumeli Hisarı on the return trip; sometimes they also stop at Ortaköy , Çırağan Palace or Dolmabahçe Palace on the return trip. From Sarıyer, bus No 25E makes the slow trip back to Eminönü, No 40 and 25T to Taksim Square and No 40B to Beşiktaş. Those to Taksim and Beşiktaş go via Emirgan, Rumeli Hisarı, Bebek, Ortaköy and Yıldız. The ferry arrives at Sarıyer at 11.45am, 11.10pm (June to September) and 2.45pm (June to September).
Click here to submit your review.
Kucukayasofya Mh. Sultanahmet Istanbul, 90, 34122 Turkey
email@example.com • +90 212 518 03 20


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People buy from people they know and like. This is even more relevant if most of your sales are made online. Today, being online can account for 100% of the sales you make. There are over 1 trillion sales generated via the Internet so you would be leaving a lot of money on the table… Read More »


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Former Spode factory to host dance music night
23 November 2017 Local News
The iconic China Halls at the famous Spode factory will host one of the biggest nights in the history of Stoke-on-Trent club culture – with up to 2,500 people set to attend.
On Saturday, December 2, six underground dance music DJs will take over the huge factory floor of the former works and transform it into a music venue for one night.
Organisers The Move have worked closely with Stoke-on-Trent City Council, which owns the historic site, to arrange the event. It will be the first time the factory, which dates back to 1776, has been used for an event like this.
Potteries-born DJ and promoter Lee Fredericks, who is one of the spokesmen for the event, said: "We've been talking about putting an event on like this in the city for several years. With Stoke-on-Trent in the running to win UK City of Culture 2021, and Spode being such an iconic and important venue, the timing for it is perfect. Spode is an incredible, atmospheric space to put on something like this and we're thankful to the council for its support because without it, there wouldn't be an event.
"We've had an incredible response from the public and ticket sales have been going incredibly well. The line-up on the night is as diverse as it is impressive in dance music circles and there's been a lot of interest from all over the country. Stoke-on-Trent has such a rich history of dance music and it would be great to have more events like this in the city."
The venue will be accessed from the new entrance on Kingsway and the event will run from 8pm to 6am, and will feature a licenced bar. The event follows the successful launch of 43 artists' studios at Spode Works last year, the hosting of the British Ceramics Biennial, the new Deb McAndrews play "Dirty Laundry", and the recent opening of a café on the site.
Councillor Daniel Jellyman, cabinet member for regeneration at Stoke-on-Trent City Council, said: "The resurrection of the Spode site over the last couple of years has been fantastic to see, with it now being viewed as a thriving centre for arts and culture in the city. Spode has so much potential to be a catalyst for regeneration – not just in Stoke town but across the whole city.
"The council has worked closely with the organisers of the event to help put on something which has never been seen before in Stoke-on-Trent and I think we're as excited as they are to see this iconic space being used in this way."
Tickets can be bought via themoveuk.com.
The Hitmix China Halls, Spode Factory, Stoke-on-Trent City Council


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Knackered Ray Winstone is taking a hiatus from HollywoodNovember 23rd, 2007 - 4:43 pm ICT by admin
Washington, Nov 23 (ANI): Actor Ray Winstone has revealed that he is taking some time off from movies because his busy schedule has left him knackered.
Winstone has worked in several recent blockbusters including The Departed, Beowulf and the forthcoming Indiana Jones And The Kingdom Of The Crystal Skull.
And his high profile has ended up in giving him a variety of offers.
However, the 50-year-old actor has revealed that he is determined to keep his work schedule clear for the near future no matter how beneficial it is.
"I just turned one down. It was a biggie, and good and all. But I thought, 'I've had enough for a while. I'm knackered. I need to recharge my batteries'," Contactmusic quoted Winstone, as saying. (ANI)
- Harrison Ford 'would love' to do another Indiana Jones flick - Nov 09, 2010
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- Indiana Jones 'to tackle Bermuda Triangle in fifth film' - Jun 10, 2010
- Harrison Ford Refuses To Appear On Piers Morgan's CNN Show - Jan 14, 2011
- Actor Shia LaBeouf Disparages 'Indiana Jones' Sequel - May 19, 2010
- Sean Connery to return as Henry Jones in 'Indiana Jones' movie - Sep 19, 2009
- Shia LaBeouf Criticizes His Own Performance In Indiana Jones Sequel - May 19, 2010
- Bang For The Buck Stars Of Hollywood - Sep 02, 2010
- Gibson took Winstone's advice for 'The Beaver' - May 16, 2011
- Harrison Ford set for 'Indiana Jones 5' - Sep 15, 2009
- Heart patient Sean Connery refuses to give up red wine - Oct 11, 2009
- Spielberg doesn't like overuse of special effects - Jul 11, 2010
- Fifth Indiana Jones movie in the offing - Jun 18, 2009
- Crowe struggles to reach sets of 'Noah' - Aug 10, 2012
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ITN has today outlined its 2020 Vision to take the company forward to the next stage of its development and capitalise on new growth opportunities.
Setting ambitious financial targets, ITN announced a number of strategic priorities aimed at achieving revenues of £180m+ the end of 2020.
The strategy puts a key focus on driving growth in businesses outside of TV News, accelerating organic diversification of output to generate more than 50% of total revenues by 2020.
It also sees an expansion of ITN's total footprint, including a push to grow its US presence five-fold over the period to generate 10% of revenues by 2020.
John Hardie, ITN CEO, said: "ITN is evolving from a position of strength and the opportunities are there for the taking. After achieving record revenue in the last financial year and six successive years of sustained operating profit growth, we are well placed to build upon that momentum."
ITN will reorganise its operations into two business divisions: Broadcast News and ITN Productions.
As supplier to all three commercial PSBs, Broadcast News comprises the multi award-winning news services for ITV, Channel 4 and Channel 5. This business will continue to be the single largest contributor to ITN's revenues and its editors will continue to report directly to the CEO.
ITN Productions will be made up of four new distinct businesses; TV Production; Sports Production; Advertising Production and Digital Content Services.
ITN Productions will be led by Mark Browning in the newly-created role of group managing director, ITN Productions and reporting directly to the CEO. The success of this division has been a game-changer for ITN, ranked already as one of the biggest independent producers in the UK. Formed in 2010 with a turnover of just £7m, today it is a £24m business and growing fast.
The TV Production business will be run by editorial director Chris Shaw. Its output has won both critical acclaim and achieved commercial success with series commissions from every major UK broadcaster as well as US channels such as Discovery and A+E. Last year alone, ITN Productions won 11 major awards including two BAFTAs, an International Emmy and a Peabody for its work.
Advertising Production, which includes branded content services, will be overseen by former Saatchi and Saatchi managing partner Laetitia Rennie. In the last two years, its adverts have garnered four Gold Media Week Awards and the Grand Prix in addition to two Gold Cannes Lions for the Lego-themed adverts for BT and Confused.com. Its client base includes Suzuki, Nat West, Samsung, Thomas Cook and Barclays.
The Sports Production business is already one of the world's biggest football producers. With unrivalled expertise in fast-turnaround for live productions across broadcast and digital, last year saw a transformative multi-million pound three year deal to film 1,800 Football League matches, capturing every game in every league. It also produces near-live match clips and highlights for Sun+ Goals and The Times across the Barclays Premier League, Scottish Professional Football League, Aviva Premiership Rugby, England international cricket, Emirates FA Cup, England International football and Tour de France. Recruitment is underway for the new role of director of sport and an announcement will be made in due course.
Digital Content Services will be led by Managing Director, Andy Williams. This unit brings together ITN's diverse portfolio of digital content offerings, including the production of short form news and entertainment content for online and mobile news sites and portals such as MailOnline, guardian.co.uk and AOL, as well as ITN's Industry News service which creates news-style programming for industry associations and professions in both the UK and US. It will also include ITN Source, which syndicates daily news footage to international broadcasters, as well as licensing ITN's archive – the UK's first fully digitised news archive – and third party collections to a global client base. ITN Source will continue to operate as a globally recognized brand alongside ITNedu, a recently launched business targeting the digital education sector.
ITN CEO John Hardie continued: "Our numbers tell the story of our success, with revenues up 25% on 2010. The 2020 Vision growth plan sets the bar even higher to release the incredible potential that I am confident ITN can achieve as a world-class production company."
About ITN:
ITN is a world-class production company made up of two business divisions: Broadcast News and ITN Productions.
It provides:
ITN: Trusted to Tell the World's Stories
Back to All Press Releases


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- Paul E. Dunlap
- Tel 984-287-4222
- P.O. Box 12233Mail Drop E1-05Durham, N.C. 27709
Paul Dunlap is a biologist in the National Toxicology Program (NTP) Laboratory at the National Institute of Environmental Health Sciences (NIEHS). He participates in the study and data collection of the NTP WormTox Screening Facility.
Since 2006, Dunlap and the rest of the WormTox group have used the nematode Caenorhabditis elegans as an alternative model organism in high-throughput toxicological screening. Most recently, Dunlap has participated in studies comparing the toxicological effects of methyl mercury and inorganic mercury on a yeast deletion library using a high throughput robotic platform. More recently he has studied the effects of toxicants on mitochondrial function in living nematodes.
Dunlap received his B.A. in biology from Earlham College in Richmond, Indiana in 1986 and he completed graduate studies at the University of Colorado-Boulder in 2002. Before joining NIEHS in 2006, he worked in the laboratory of Jonathan Freedman, Ph.D. at Duke University's Integrated Toxicology Program.
Selected Publications
- Jin YH, Dunlap PE, McBride SJ, Al-Refai H, Bushel PR, Freedman JH. Global transcriptome and deletome profiles of yeast exposed to transition metals. PLoS Genet. 2008 Apr 25;4(4):e1000053.
- Alper S, Laws R, Lackford B, Boyd WA, Dunlap P, Freedman JH, Schwartz DA. 2008. Identification of innate immunity genes and pathways using a comparative genomics approach. Proceedings of the National Academy of Sciences of the United States of America, 105(19):7061-7021. [Abstract]
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Bodiam Christmas Special !!! Check out this all-inclusive car service special
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* Occupied lifts for full-size vans
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For over a decade, Custom Technology Company, Inc. has been providing Central Washington with expert advice and quality equipment to make getting "out and about" a pleasant experience for our clients! From occupied lifts for your full-size van, to exterior lifts for your car or truck, we can help you take your favorite chair or scooter with you in nearly ANY vehicle! We can provide automatic docking stations, door openers, remote deployments, interlock systems, passenger and chair restraints, electric swivel seats, and much more!
Representing some of the most trusted names in mobility solutions, Custom Technology Company, Inc. is well-equipped to offer solutions for you or your loved ones. Please contact us today to ask how WE can help YOU!
Vantage Mobility International supplies quality, reliable platform lifts for full size (& some smaller) vans. With payloads of up to 800lbs and designs featuring unobstructed seating and doorways, VMI will likely have a lift to fit your lifestyle.
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Click on one of the logos above to take you to just some of the products we can offer. We do not install hand controls at this time, but we can recommend people who do.


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Oct 29
Happy Monday! Hope everyone is staying safe and dry! In honor of our little friend Sandy, I thought I'd re-post a Meg Kelsey original on hurricanes from way back in 2010. Enjoy and stay safe!
Storms are coming, literally! Our church service started with an announcement about the upcoming hurricane season, which is a big deal here in Miami. Our church has a special Hurricane Assistance Program for hurricane preparation, survival and recovery. Everyone is asked to fill out a bright orange form with a checklist of either the services you are able to offer or that you need help with, as well as materials/tools you could lend to a neighbor in need. What an important and resourceful ministry!
As Scott and I were checking off items, it hit me how much we need community in the event of a major storm. Even though I have been through hurricanes in Virginia, the announcement was a wake-up call to how serious the storm season can be in South Florida. I felt supported just knowing we can get help in preparing for and facing a storm, that we could borrow a chainsaw, satellite phone or even a pick-up truck if needed. Plus, a potential benefit once the storm has passed was alluded to in one of the checklist items to share: "A party house while we are off work." Check!
As Scott and I were checking off items, it hit me how much we need community in the event of a major storm. Even though I have been through hurricanes in Virginia, the announcement was a wake-up call to how serious the storm season can be in South Florida. I felt supported just knowing we can get help in preparing for and facing a storm, that we could borrow a chainsaw, satellite phone or even a pick-up truck if needed. Plus, a potential benefit once the storm has passed was alluded to in one of the checklist items to share: "A party house while we are off work." Check!
Hurricanes can come in the emotional, relational and spiritual variety as well. The topic of the sermon and our small group discussion later in the evening was the all-consuming storm that Job endured in losing his family, home, and health. Both the sermon and the discussion were heavy emotionally. I found myself on the verge of tears as I heard the familiar story of Job's devastating loss as well as the new stories of people in our community group who have suffered and dealt with horrendous storms. Part of me wanted to skip to the end of Job's story and just celebrate the happy ending, his doubled blessings and increased prosperity. But storms are a fact of life. As Elizabeth said in Friday's post and yesterday, there is no question about if we will have trouble, but rather John 16 assures us that we will indeed face storms.
But WHY do we face these storms? Last week Anna Kate wrote about having questions and turning to the Lord in uncertainty. One answer that always rings true : God is in control. A recent Oswald Chambers' devotional said, "It is adversity that makes us exhibit His life in our mortal flesh… Our circumstances are the means God uses to exhibit just how wonderfully perfect and extraordinarily pure His Son is." I may not understand why I am facing a certain trial, or why a friend is being challenged by a certain storm, but we are promised that as our faith is refined in the fire of trial it brings honor to our Lord.
Praise be to the God and Father of our Lord Jesus Christ! In his great mercy he has given us new birth into a living hope through the resurrection of Jesus Christ from the dead, and into an inheritance that can never perish, spoil or fade… In this you greatly rejoice, though now for a little while you may have had to suffer grief in all kinds of trials. These have come so that your faith—of greater worth than gold, which perishes even though refined by fire—may be proved genuine and may result in praise, glory and honor when Jesus Christ is revealed.
1 Peter 1:3-7
Rather than an inward gaze, our focus should always be on the living hope through the resurrection of Jesus. In Elizabeth's case, an actual hurricane before her wedding readjusted her priorities. And the sun shining through the clouds upon leaving the chapel was a bright and beautiful testimony to every single guest in attendance of God's goodness and sovereignty. We all looked up to the sky in joyful disbelief!
But we don't always have a literal ray of light to draw our gaze upward. In the same Oswald Chambers devo mentioned above, one question made me slightly uncomfortable: "Is my life exhibiting the essence of the sweetness of the Son of God, or just the basic irritation of 'myself' that I would have apart from Him?" When going through extreme adversity it is difficult to lift my eyes up. To cry 'Woe is me!" feels so satisfying. However, I must remind myself that self-pity does absolutely nothing to advance the kingdom of God. I cannot exhibit anything sweet without losing myself and seeking more of the Lord.
Some trials, such as the death or sickness of a loved one, do bring such grief that it takes time to process the loss, to regain a genuine hope in His good plan. Tomorrow we will look more into the need for the support of community in general and especially during trials. Just as the Hurricane Assistance Program is a practical, living testimony of the love of Christ here in Miami, how we, as the body of Christ, love and support one another in all circumstances will be a testament to others of "how wonderfully perfect and extraordinarily pure the Son is."
This Tuesday, amidst storm and adversity, we can rejoice in our Almighty God. Embedded below is a great Hillsong worship song. Sing aloud (or, if at work, read in your head emphatically) the empowering cry, that our Lord is stronger through the storm and through the fire. Let His name be lifted higher!
There is love that came for us, Humbled to a sinner's crossYou broke my shame and sinfulness, You rose again, victorious
Faithfulness none can deny, Through the storm and through the fireThere is truth that sets me free: Jesus Christ, who lives in me
You are stronger, You are stronger. Sin is broken, You have saved meIt is written, "Christ is risen". Jesus, You are Lord of all
No beginning, and no end, You're my hope and my defenseYou came to seek and save the lost, You paid it all, upon the cross
So, let Your name be lifted higher. Be lifted higher, be lifted higherSo, let Your name be lifted higher. Be lifted higher, be lifted higher


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Typically our ideal client looks like:
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Fairfield Island Homes For Sale
View all the MLS listings for 2, 3, 4, 5, 6 or more bedrooms single-family detached homes, houses, properties and real estate for sale in the Fairfield Island area of Chilliwack, BC. You can browse through other areas or dwellings by clicking the menu above. Call Mindy Mcpherson today at 604-826-1000 to view any of these listings.


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Connect Hearing Calgary - Avenida
12445 Lake Fraser Drive SE 211
Calgary, AB, T2J 7A4
Toll Free: (888)501-2661
To find our clinic, when you are traveling on McLeod, exit on Lake Fraser Gate, and turn left on Lake Fraser Drive. We are located in Avenida Village (not Avenida Place) on Lake Fraser Drive. You'll find us in between Eagles Med and Avenida Denture Clinic, across from the La Picola, Aladdin's and Halo's restaurants. Plenty of free parking is available in the mall lot. Our clinic is wheelchair accessible.
Call or visit us at the Connect Hearing clinic in Calgary Avenida today for a complimentary hearing evaluation. It's quick, easy and will confirm the health of your hearing. If your test reveals that you would benefit from hearing aids, a qualified professional will make a recommendation, with no cost or obligation.
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|I have a perennial garden that is mostly hosta varieties, there are a lot of weeds that look similar to a dandelion but are covered in thorns (small but painful!) when I try to pull them out they have a long taproot similar to dandelions so I am going to have to resort to a herbicide - can you recommend one that won't harm my hostas in close proximity?
|About the only thing safe for your hostas is to spot treat those nasty weeds with a spray of Round Up. It will kill anything it touches so you may need to set a cardboard box over each of your hostas while spraying the weed killer. Round Up stays in the weed and travels down to kill the roots but does not move in the soil so your hostas will be safe - as long as you keep the spray and the drift off of them. Best wishes with your project!


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One of the most important of Tai Chi's many supporting exercise routines is chansigong, otherwise known as "silk-reeling" or "spiral-power" exercises. Silk-reeling is used to develop whole-body coordination, core- and lower-body strength, and especially to cultivate the interface between mental intention, action, and the spiraling flow of internal energy, or chi.
Since the routine is low aerobic and non-impact, it's appropriate for almost anyone, including older athletes, those recovering from illness or injury, and those working to overcome long-standing chronic conditions.
- Date: Thursday, June 5th
- Time: 1-2pm
- Location: DIAKADI
- Cost: DIAKADI Trainers and DIAKADI Clients FREE | Community $30
- Presenter: Malcolm Dean
In this short workshop, we'll be using the spiral power exercises of Grandmaster Feng Zhiqiang to explore the nature and power of the Energy Body—a concept very real in Traditional Chinese Medicine, acupuncture and Tai Chi, but still somewhat an enigma in the West. Our aim will be to make this esoteric concept of practical use in all everyday activities. Specifically, we'll look at:
- The Four Bodies
- Mindfulness in motion
Anatomy of the Energy Body as used in the marital arts:
- The central dantian
- The major energy channels
- The important acupuncture points
- Working with the Energy Body in action:
- Moving from the center (dantian)
- Creating the microcosmic orbit (in all three body planes)
- Creating the internal chord (the root of internal strength)
Presenter: Malcolm Dean
- Founder, SF Hunyuan Tai Chi Academy
- Gold Medalist, Men's Forms, 1st International Hunyuan Tai Chi Symposium, Beijing, 2007


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Where have our feelings gone?31 Oct 2016, Posted by Monthly Blog in
I was running a session as part of leadership programme for high potential leaders in a global organisation.
We'd got to the bit where we use FIRO-B, a psychometric tool that explores our relationship with our need for control, for closeness in our relationships and the degree to which we are open with other people. I became aware that a woman was frowning and trying to catch my eye.
'What', she eventually said, 'did this possibly have to do with leadership?.
'Why', she added, 'are we exploring all this … touchy feely stuff?'
That was at least two years ago. I have never forgotten it. Not least because my response mostly involved standing there like a fish and struggling to find the words to respond. Because nothing is more clear to me. Our awareness of our own internal processes and how we show up with others is core to leadership. How we feel about ourselves and other people matters deeply.
But also because I keep seeing this theme in my work and it's bothering me. Drawing on recent experiences of coaching and facilitating leadership development, how come someone (of course, a composite of different someones)…
• is so focused on delivering the tasks that he gets hardened to the feelings of the people involved and around him – and actually says to me he
• doesn't much care how they feel as long as the job gets done
• says that feelings have no place in the workplace
• says that giving people encouragement and appreciation leads to complacency
• simply cannot name any of her feelings when invited to do so as part of a 'check in' at the start of an action learning set
• is so disconnected with his own feelings that he's utterly thrown – but completely engaged – when I encourage him to name and explore his anger and where that comes from, and connect with his feelings of vulnerability and his longing for someone to understand him
In her (highly recommended) book The Will To Change, the author bell hooks puts forward the view that our work and the way we are working today sets us up to have no space for emotional connection and that it creates a sense that we 'should be willing to sacrifice emotional connection in order to get the job done'.
That makes me desperately sad. It rings true. But equally, I am determined to find the words to persuade people that our emotional life has a valid place in our working life.
What's your experience of this? Do you have similar stories? And how do you respond?


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This weekend I had the chance to handle the new CzechPoint Vz.58 SBR that will hit the market this fall. I'm excited about the introduction of this rifle as I'm a fan of the full-size Vz.58 which really hasn't gotten the attention it deserves in the U.S. market.
The rifle is being built by CzechPoint and exclusively distributed by AGS Armament. I've been promised one of the first production models off the line and will give you a full report on it once I have a chance to thoroughly wring it out. Here's what I know so far.
CzechPoint takes a standard Vz.58 rifle and shortens everything forward of the receiver (gas system, barrel, handguards, etc.). Two versions will be available. The one you see here has a heavily truncated front handguard making it an exceptionally short package. The other (not pictured) will have a standard sized front handguard and will be about 4″ longer over all. The super short SBR (pictured) will have a length of 28″ with the stock extended and 19″ with the stock folded. That's a VERY small package. I didn't have a scale on hand to weigh the rifle, but I will say it felt as though it's less than 6lbs so it's a very light package as well.
The front sight post is much finer than a standard Vz.58 front post which helps in obtaining a more useful sight picture with the short sight radius. The rear sight is typical for the rifle with graduated elevation adjustments up to 800m, which I find to be more than a bit optimistic for a 7.5″ barreled 7.62×39 rifle. I would say it has a practical effective range of 200m or so at best.The rifle is chambered in 7.62×39 with rumblings of a 5.56×45 version down the road. The muzzle wears a CzechPoint designed muzzle brake that adds another 1″ or so to the length and is said to be effective, however I didn't have a chance to shoot it to confirm the effectiveness.
The rifle I handed didn't have a left side accessory rail for mounting optics. The final production version will have drilled and tapped holes so you can attach a rail mount yourself (sold separately). This will give you the option of mounting optics in a similar fashion to how they are mounted on AK's.
The aluminum 30 round magazines will be abundantly available. The gun has a very nice fit, finish and fell to it. I did notice it wears a Mako Group type pistol grip which I've found to be very ergonomic on the Vz.58.
The price will be in the $1,100 – $1,300 range, plus don't forget the pesky $200 NFA tax for it being a SBR. However I will say this, I want one. Bad. It's amazingly light weight, short, handy and quite possibly one of the best truck guns you'll find on the market assuming it works as good as it looks.
A lot of people mistake the Vz.58 as a relative of the AK-47 — but it isn't. The only two things the Vz.58 has in common with the AK-47 is the caliber and a similar outward appearance. Internally the two are nothing alike. The gas system, trigger system, magazines, stocks, safety, etc. are all quite different and not a single component is interchangable between the two. The Vz.58 has earned a stellar reputation for reliably though, which is another attribute it shares with the AK-47.


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Today was Mary's 15th Birthday and everything was supposed to be perfect and it was until she received a mysterious gift and no sender. What she sees inside changes her life, or what's left of it anyway.
- birthday
- blood
- card
- death
- doll
- game
- gift
- mary
- mirror
- puppet
- tears
annabeth247 Jul 09, 2011
coolness i don't usually like being creeped but im reading on :) thts how magical it is
deathsXaccomplice Nov 14, 2010
@xShyStoryGirlx Thank you for reading! I'm glad you liked it!
deathsXaccomplice Nov 14, 2010
@ashbash87 This is just the first part. I will continue this very soon! Thanks for taking the time to read it. I will try and take a look at your stories as soon as I can.
ashbash87 Nov 14, 2010
its ok but i think it eeds more does mary die?..... read my stories please
deathsXaccomplice Nov 11, 2010
@Yalevolyda Yeah it is! I really appreciate all of the support!!
Yalevolyda Nov 11, 2010
@deathsXaccomplice I'm glad you feel that way~ It's nice doing good deeds for once, yeah? =]


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Top 10 ArticlesA Whale of an Encounter
About GBRMPA
Advanced Diving
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Butterfly Fish
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SnorkellingUpdated: 15-Feb-2007
Snorkelling the
As an activity, snorkelling is within the reach of practically everyone. It does not ask for expensive or complicated equipment, and the basics are easy to learn. It's also ideal for people of practically all age groups and is perfect as a family activity or with friends.
If you haven't snorkelled before, all marine tour operators will offer complete instruction before you enter the water and friendly crew will be on hand to assist you.
The only requirements are the ability to swim and fairly good fitness as snorkelling is a strenuous activity. If you need to rest while snorkelling some reef locations offer a snorkel rest station or a guide line to hold onto.
Snorkel sites are supervised and swimming aids and flotation devices are available allowing all to experience the magic of the
Most marine activity takes place in the top 4 metres of the ocean, so you will be able to view just as much marine life from above as the divers do below; just looking from a different perspective.
To learn more about the marine life around you, why not consider taking a guided snorkelling tour? Many reef operators offer Free Snorkel Tours guided by a Marine Biologist. It's a safe way to expand your boundaries and discover more about the wonders of the
Remember to take care with the sun though; snorkelling can occupy you for hours. It is recommended to hire a stinger suit or wetsuit from your reef operator. It not only protects you from marine stingers, it also protects you from the strong
Do not be deceived by overcast days, you can still get sunburnt!


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By Jodi Smith June 7, 2018, 2:58 PM EDTLaw360 (June 7, 2018, 2:58 PM EDT) -- The California Safe Drinking Water and Toxic Enforcement Act of 1986, better known as Proposition 65 or Prop 65, requires companies conducting business in California to warn consumers prior to exposing consumers to specific chemicals that have been identified pursuant to Proposition 65 as being chemicals known to cause cancer or birth defects or other reproductive harm. The Prop 65 regulations were substantially revised in August 2016 and the new regulations go into effect on Aug. 30, 2018. The new warnings can be used now, but...
Will Your Business Be Ready For The New Calif. Prop 65?
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we're back from our trip and still catching up. the amazing news is that our RADicals MISSED US! i had low expectations (so it wouldn't hurt my feelings) but they were so happy when we got home and were very clingy for days! shocked me! they had a fine time with the grands, ate sugar, stayed up late, mucho attention, but they missed us they said. amazing, and very comforting.
em even crawled in my lap yesterday for a cuddle for no reason, now that is progress!!
and we were gone for mother's day, but i came home to this letter from my 6 year old: "i love you mom. mom you make me happy. mom you are fun. you cook good." now THAT made my day!
Monday, June 8, 2009
home, they actually missed us, mom's day note
Posted by Unspeakable Joy at 12:07 PM
1 comments:
- Perspective RAD said...
WOOHOO! That's GREAT!
- June 8, 2009 at 7:27 PM


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Learning and Teaching Enhancement Strategy
The Learning and Teaching Enhancement Strategy (2017-2021) is a values-based strategy designed to provide a 'common language' to support the development, sharing, and enhancement of learning, teaching and assessment practice across the university. The strategy was developed through extensive consultation and review across the university. It is intended to complement and extend learning and teaching policy and practice within and across the Academic Partners of the university, and provide a means to both recognise existing good practice and to develop our future practice.
The Learning and Teaching Enhancement Strategy comprises four key components:
- Twelve Learning and Teaching Enhancement Values that provide the basis of the strategy itself, and of a common language for learning and teaching enhancement
- A set of implementation actions and objectives for the embedding of the aforementioned values in institutional policy, practice and professional development provision across the five year timescale for the operationalisation of the strategy
- Mapping of the values to illustrative examples that provide a general sense of direction or insight into how each of the values could be represented in practice
- Mapping of the values to key internal and external policies and benchmarks, to articulate the broader internal and external relevance and applicability of the values
Embedding the strategy
Commencing from the start of the academic year 2017/18, the formal embedding of the strategy will begin as outlined within the implementation actions and objectives contained in the strategy itself. This will include a range of activities to be taken forward through the Learning and Teaching Academy to help colleagues engage with the strategy and embed, or further embed, the values of the strategy within their own practice. We will also be creating resources, including good practice case studies, to help further illustrate a range of ways in which the values can be embedded, and to support further engagement with the strategy going forward.
The Learning and Teaching Academy can also offer opportunities and events within Academic Partners, Faculties and Subject Networks to support engagement with the Learning and Teaching Enhancement Strategy. If this would be of interest to you please contact us at email@example.com.


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When the apocalypse arrives, life goes on. That's the possibility some are preparing for, at least.
In 2008, Larry Hall purchased a retired missile silo (a vertical, underground structure made for the storage and launch of nuclear weapon-carrying missiles) for $300,000 and converted it into luxury apartments for people who worry about the end of the world and have cash to burn.
Fortified shelters, built to withstand catastrophic events from viral epidemic to nuclear war, seem to be experiencing a wave of interest in general.
Someday, the 1% may live out Armageddon in style at Hall's Survival Condo Project, which cost $20 million to build and accommodates about a dozen families. Complete with food stores, fisheries, gardens, and a pool, it could pass as a setting in the game "Fallout Shelter," wherein players oversee a community of post-apocalyptic residents in an underground vault.
Take a look inside one of the world's most extravagant doomsday shelters.
Larry Hall, who previously developed networks and data centers for government contractors, got the idea to convert the base after the attacks on September 11, 2001, when the federal government began reinvesting more heavily in catastrophe planning.
A full-floor unit is advertised for $3 million, and a half-floor unit goes for half the price. But good luck getting in. The units sold out before construction ended in 2012.
Halls has a new, second silo in the works that is 50% complete and will wrap construction in fall 2018. About half of the units have been spoken for, with more available for purchase.


text: This incredible three - level modern contemporary, which has been renovated all green.Boasts 6 bedrooms, 5.5 baths. A Cooks Dream with Dual Viking Stoves, Dual Dishwashers. Master bedroom comes equipped with jacuzzi and steam shower. Double sided fireplace makes for a very cozy night. Cedar sauna comfortable fits 8.Enjoy the panoramic Ocean and Bay Views. A heated salt water pool, hot tub, outdoor shower and a pool house with kitchen and full bath. You can control your audio and video from your IPAD. A summer you will remember forever.


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Manufactured by Pico Pao
Product code: PICO-2000
El Balancin game by Pico Pao.
This game is based on two of the oldest and most basic play activities known: stacking and balancing. People have been playing with these elements since the dawn of time. Both possibilities – standing up or falling over – can be equally exciting.
The pieces of the game are of seemingly arbitrary shapes, the sort of thing which immediately appeals to children. The building potential of simple objects is something that not only children, architects and engineers have observed; the first abstract artists were quick to capture the tension produced by the juxtaposition of objects.
The field of abstract constructivism is really a reversion to the simplest and most fundamental of our childhood games, what we called 'building something'. Often it was something that we could not put a name to, other times it would be a city or a dragon, which after coming to pieces would be rebuilt as a bridge, a cylinder, a triangle….or simply a lot of pieces scattered around on the floor.
Number of pieces: 25 black and grey pieces and 12 cylinders.
Materials: Wooden MDF case. Pieces made of MDF, cylinders beech wood
Case - 25w x 6.5d x 23.3cmh
Product downloads
To-order: 2-4 weeks
Select a size for delivery price
Delivery Mainland UK £5.95
Accessories orders over £100 free for Mainland UK.
Non-Mainland UK and International options available in basket


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Torrey's Topical TextbookSongs 2:1
I am the rose of Sharon, and the lily of the valleys.
Torrey's Topical Textbook
What the Flowers Say.
The Best of the Best
The Preaching of Nature.
Chapter ii.
On Fruit Bearing.
Paradise on Earth.
Paradise on Earth.
The Unsatisfied Life and Its Remedy
The Creation
Spiritual Appetite
Flowers: Cultivated in Gardens
Flowers: Garlands of, Used in Worship of Idols
Flowers: Representations of, on The: Golden Candlestick
Flowers: Representations of, on The: Sea of Brass
Flowers: Representations of, on The: Wood Work of the Temple
Flowers: Shortness of Man's Life
Flowers: The Lily of the Valley
LinksBible Concordance • Bible Dictionary • Bible Encyclopedia • Topical Bible • Bible Thesuarus


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Learning a new language expands your career potential?
With universal unemployment problems, being bilingual will definitely give you a competitive edge over others. It is an ability that tells of a person's intelligence, flexibility, openness to diverse people, and decision-making skills.
At iSpeak, we often have people who take our classes to get ahead in the workplace. Let us help you take the next step to stand out at your job!


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Personalized Nikkah With 250+ Terms
Getting married and need a nikkah? Nikkah Builder has over 250 unique curated terms that you can include in your personalized nikkah. Sign up for a free account to get full access to create your personalized nikkah.
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Free To Use
Nikkah Builder is a free service for personal use.


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Bit-X Ensures Convenience When Trading In Bitcoin
Fans of Bitcoin slots and online gambling in general are always on the lookout for things that would make their lives easier. This is the reason Bitcoin has become so popular among players at online casinos.
The cryptocurrency cuts past the expensive transaction fees and lengthy approval times, making everything simpler for many people. A lot of players and gambling operators have recognized the Bitcoin casino advantages and have adopted it as a favored currency.
There is a bottleneck, though, when it comes to dealing in Bitcoin: the conversion of bitcoins into other currencies. This is usually done through a Bitcoin exchange. The trouble is that some Bitcoin exchanges do not have all the features that a person need when it comes to Bitcoin transactions. For instance, some exchanges only deal in a specific currency like US dollars.
Savvy Bitcoin gamblers will pick the ideal Bitcoin exchange to do business with to minimize the problems they may face when trading their bitcoins into fiat cash. This is where Bit-X comes in. Based in the UK, this Bitcoin exchange can make a lot of lives easier with its multitude of features.
Convenience foremost
The Bit-X Bitcoin exchange adds several layers of convenience for anyone using their services. First of all is the easy-to-use interface.
Many Bitcoin exchanges have complicated interfaces that would be easy for an expert but would leave many laypeople lost or at least incapable of using them to their full functionality. With Bit-X, users would be able to fully understand what they can do with their accounts.
Second, Bit-X trades in several important currencies, giving users increased flexibility in their trades. The exchange trades primarily in Bitcoin but now also accepts Litecoin. For fiat currencies, Bit-X started out with US dollars, the UK pound, and the Euro. This selection guarantees that over half the world is serviced by the exchange.
A recent addition of the Russian ruble just adds to how much coverage the exchange can give. Furthermore, Bit-X always gives the best possible market prices when trading.
Finally, Bit-X gives its users as much information as possible so that they can best decide on their options. This extends from transparency in terms of user transactions—with people having access to their account activity—to the current state of the market. People are guided to make an informed choice on their trading decisions through the live updates and charts provided.
Other attractive features
The main trading experience is not the only factor that should attract Bitcoin gamblers to Bit-X. There is the fact that the exchange takes security seriously. It uses a two-factor authentication system to secure accounts, which can make it difficult for any potential hacker to come in and steal the bitcoins inside.
Another feature that many will find useful is the fact that Bit-X has a round-the-clock client support. This makes handling emergencies easier and can have account owners breathe easier.
Bit-X is an ideal partner for any smart Bitcoin gambler who hopes to get the most out of their winnings from playing Bitcoin games on board top casinos online.


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discuss the market segmentation within that industry along with the target market for the company and the selection process for that target market.
The Gap Inc. is a global specialty retailer that operates stores selling casual apparel and accessories for men, women, and children (Yahoo Market Guide, 2001). Under the Gap, are the Old Navy and Banana Republic brands (Yahoo Market Guide, 2001).


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Do You Have an Idea Why Industrial Cooling Tower Has So Much Significance In The Market?
Industries have become more productive these days. May be the reason is industrial cooling towers they installed in the premises. These systems are critical as more than hundred manufacturing processes are being used to create heat, or using them as input in few stages of the processes. Cooling towers are used to maintain the temperature of the devices and applications connected to it. When these towers are installed in a factory, these devices expel the excessive or unwanted heat and introduce cold water or fluid to absorb the increasing heat.
To make it functional device, it must be based on a constant flow rate and temperature. A great design and proficient installation of water cooling tower can bring various benefits to the user, such as quality production, consistency, and lesser wastage. Cooling towers contribute to enhance productivity and manufacturing process. Thus, you can find them safer in use and environmental friendly.
The industrial cooling systems range includes cooling towers, air and water, water cooling, blast furnaces ethylene glycol coolers, and cooler.
HVAC technology based cooling chillers are far better than air-cooled chillers in terms of efficiency. Air cooled water chiller should be able to refuse in the dry-bulb temperature of heat.
The cooling tower technology is adopted by several industrial processes worldwide and it is being into existence since 19th century. It is true that initially the technology was introduced back in 19th century with the development of condensers that were installed and used with steam engine. These condensers were using cool water through various means in order to condense the steam released by the pistons or turbines. This helps lowers back pressure, and instantly reduces the steam absorption. Thus, the absorption of fuel at the same time increases power and reuses boiler water.
Today, industrial type cooling towers are employed at the site to reject the heat from various sources, such as machinery or heated process material. These large industrial purposes cooling towers are primarily used to expel the heat absorbed in the recirculating cooling water systems. These towers are installed at various power plants, petrochemical plants, petroleum refineries, food processing units, and other industrial facilities.
However, a sudden failure in cooling towers may result in unexpected downtime. The mechanical parts in cooling towers face the stress due to varying loads and large rotary fan blades. With the help of wireless technology, experts have determined the potential issues, and have schedule maintenance to eliminate unexpected downtime risk.
The device has an AC motor with a long shaft connected to a gearbox. The fan and other drive parts of the system experience more depreciation than any other parts. Users operate them under varied conditions and with distinct stresses over a long period. Due to such reasons, the mechanical components become inefficient in performance and this result in failure of cooling tower.
To get reliable industrial cooling tower equipment for your site, you can contact Tower Tech Global experts. They are high profile manufacturers and suppliers of distinct range of cooling towers across the globe. Share your requirements and get instant response from the professionals.
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