text:
All-natural joint replacements?
GoogleNews.com, August 3, 2010 — Patients may one day be able to "grow" new joints with the help of their own stem cells.
The new joints would enable patients to have a full range of motion, and they may be more durable than the artificial joint replacements now in use.
That could mean the end of repeat operations to have an original hip or knee replacement done over because such replacements usually last only 15-20 years.
Rabbits implanted with artificial bones re-grew their own joints, complete with cartilage, researchers reported on Thursday.
Only a single compound called a growth factor was needed to induce the rabbits' bodies to remodel the joint tissue, said the team at Columbia University in New York, Clemson University in South Carolina and the University of Missouri.
Such a joint should last longer and work more naturally than a metal joint, the researchers said.
Companies involved in making replacement joints and regenerative medicine are expressing interest, said Columbia's Jeremy Mao, who led the study. "All the tissue was formed by stem cells from the host," Mao said in a telephone interview.
Writing in the Lancet medical journal, the researchers said they set out to make an artificial joint using a biomaterial made out of polycaprolactone and hydroxyapatite. "It is U.S. Food and Drug Administration approved to use the materials for bone regeneration," Mao said.
They replicated a rabbit's leg joint using a laser to calibrate the structure. They infused this porous bone scaffold with a growth factor — a compound that stimulates cells to grow. In this case it was transforming growth factor beta-3.
Ten rabbits fitted with the enriched new joint were hopping around within three to four weeks. Only a few of the 10 rabbits fitted with an unenriched scaffold could move normally, and three rabbits whose joint was surgically damaged and not repaired limped permanently.
"It was a surprise finding," Mao said. They expected it would take more work to get the body to coat the artificial bone with fresh cartilage.
In the future, could we make our own joints?
The technique could benefit patients with advanced arthritis. "At this the whole joint really has undergone substantial breakdown," Mao said.
Metal joints only last 10-15 years but this type should last longer, he said. "It's your own joint. It is the joint you made the second time around," he said.
The Arthritis Foundation says 27 million people in the United States alone have osteoarthritis. "As we age, if we live long enough, pretty much half of us will get arthritis," Mao said.
Columbia has a patent on the technology and is speaking to companies about commercial development and human trials, Mao said. "We'd like to speak with FDA," he added.
Many groups are working in the new field of regenerative medicine, which seeks to harness the power of master cells called stem cells to re-grow diseased and damaged tissue.
Some are coating bone scaffolds with stem cells and implanting them but this new method induces the body to do the job itself, saving a great deal of trouble, Mao said.
Dr. Patrick Warnke of Bond University in Australia said not all patients may have this regenerative capacity — especially the elderly.
"For most patients, a standard metal joint replacement is likely to offer a faster and less demanding option than the bioscaffold, with fewer risks associated with immobility," Warnke wrote in a commentary.
Mao's team "have offered a promising insight into what might be on the horizon", Warnke added.
Source: http://press.thelancet.com/joint.pdf.
This is an immunofluorescence image of a human mesenchymal stem cell growing on a plate of microposts, which have the approximate consistency of Silly Putty. This image was taken after one day of culturing. The red dots are the microposts, which are relatively short in this sample. The green is the cell and the blue is its nucleus. This cell will differentiate into a bone cell. (Credit: Michael T. Yang (University of Pennsylvania))
University of Michigan, August. 3, 2010 — Within 24 hours of culturing adult human stem cells on a new type of matrix, University of Michigan researchers were able to make predictions about how the cells would differentiate, or what type of tissue they would become.
Their results are published in the Aug. 1 edition of Nature Methods.
Differentiation is the process of stem cells morphing into other types of cells. Understanding it is key to developing future stem cell-based regenerative therapies.
"We show, for the first time, that we can predict stem cell differentiation as early as Day 1," said Jianping Fu, an assistant professor in mechanical engineering and biomedical engineering who is the first author on the paper.
"Normally, it takes weeks or maybe longer to know how the stem cell will differentiate. Our work could speed up this lengthy process and could have important applications in drug screening and regenerative medicine. Our method could provide early indications of how the stem cells are differentiating and what the cell types they are becoming under a new drug treatment."
In this study, Fu and his colleagues examined stem cell mechanics, the slight forces the cells exert on the materials they are attached to. These traction forces were suspected to be involved in differentiation, but they have not been as widely studied as the chemical triggers. In this paper, the researchers show that the stiffness of the material on which stem cells are cultivated in a lab does, in fact, help to determine what type of cells they turn into.
"Our research confirms that mechanical factors are as important as the chemical factors regulating differentiation," Fu said. "The mechanical aspects have, until now, been largely ignored by stem cell biologists."
The researchers built a novel type of stem cell matrix, or scaffold, whose stiffness can be adjusted without altering its chemical composition, which cannot be done with conventional stem cell growth matrices, Fu said.
The new scaffold resembles an ultrafine carpet of "microposts," hair-like projections made of the elastic polymer polydimethylsiloxane — a key component in Silly Putty, Fu said. By adjusting the height of the microposts, the researchers were able to adjust the rigidity of the matrix.
In this experiment, the engineers used human mesenchymal stem cells, which are found in bone marrow and other connective tissues such as fat. The stem cells differentiated into bone when grown on stiffer scaffolds, and into fat when grown on more flexible scaffolds.
Once the researchers observed the cells differentiating according to the mechanical stiffness of the substrate, they decided to measure the cellular traction forces throughout the culturing process to see if they could predict how the cells would differentiate.
Using a technique called fluorescent microscopy, the researchers measured the bending of the microposts in order to quantify the traction forces.
"Our study shows that if the stem cells determine to differentiate into one cell type then their traction forces can be much greater than the ones that do not differentiate, or that differentiate into another cell type," Fu said. "We prove that we can use the evolution of the traction force as early indicators for stem cell differentiation."
The new matrix — manufactured through an inexpensive molding process — is so cheap to make that the researchers are giving it away to any interested scientists or engineers.
"We think this toolset provides a newly accessible, practical methodology for the whole community," Fu said.
This work was conducted in Dr. Christopher Chen's group in the Department of Bioengineering at the University of Pennsylvania. The research was supported by the National Institutes of Health and the American Heart Association.
Story Source: The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Michigan.
Journal Reference:
- 1. Jianping Fu, Yang-Kao Wang, Michael T Yang, Ravi A Desai, Xiang Yu, Zhijun Liu & Christopher S Chen. Mechanical regulation of cell function using geometrically modulated elastomeric substrate. Nature Methods, 2010; DOI: 10.1038/nmeth.1487Top of Form
University of Michigan (2010, August 2). New insights into how stem cells determine what tissue to become.
Artificial Lung "breathes" in Rats: Study
Filed Under News | Leave a Comment
ScienceDaily.com, August 3, 2010 — U.S. researchers have created a primitive artificial lung that rats used to breathe for several hours and said on Tuesday it may be a step in the development of new organs grown from a patient's own cells.
The finding, reported in the journal Nature Medicine, is the second in a month from researchers seeking ways to regenerate lungs from ordinary cells.
In the latest study, Harald Ott and colleagues at Massachusetts General Hospital and Harvard Medical School in Boston removed the cells from rat lungs to leave a scaffolding or matrix.
They soaked these in a bioreactor along with several types of human lung cells, creating pressures to simulate the pressure inside a body to make the lung workable and flexible.
The cells took up residence and grew into different tissue types seen in a lung, Ott's team reported.
When transplanted into rats, they worked for about six hours, although imperfectly.
The researchers said it may be possible to try the experiment with more immature stem cells, the body's master cells. These could include embryonic stem cells, which can mature into any cell type in the body, or induced pluripotent stem cells — ordinary cells with genes added to make them behave like flexible stem cells.
The potential market is large and dozens of companies are launching into regenerative medicine, as are academic labs like those at Harvard.
"Nearly 25 million people live with chronic obstructive pulmonary disease and approximately 120,000 patients die from end-stage lung disease annually in the United States alone," Ott's team wrote.
"Lung transplantation remains the only definitive treatment for end-stage lung disease. As with other organs, however, the supply of donor lungs is limited. In 2005, only one out of four patients waiting for a lung underwent transplantation," they added, citing the United Network of Organ Sharing.
Last month, a team at Yale University in Connecticut implanted engineered lung tissue into rats that helped the animals breathe for two hours.
Embryonic Stem Cell Trial Back On
Filed Under News | Leave a Comment
Human embryonic stem cells
Image: Wikimedia commons, Nissim Benvenisty
The-Scientist.com, August 3, 2010, by Jef Akst — Nearly a year after the US Food and Drug Administration placed a hold on the first clinical trial of human embryonic stem cells, the company Geron has been cleared to continue its study of spinal cord injury, it announced on July 30, 2010.
"We are pleased with the FDA's decision to allow our planned clinical trial of GRNOPC1 in spinal cord injury to proceed," Geron's president and CEO Thomas Okarma said in a statement.
The Phase I trial, which aims to use human ESC-derived progenitors of neural support tissue to treat patients with severe spinal cord injury, was to be the first-ever clinical trial of a hESC-based therapy when it was cleared by the FDA in January 2009. That August, however, before any patients had received treatment, the FDA placed a hold on the trial after cysts appeared in some of the animals given the treatment in a preclinical study.
Since then, Geron completed an additional preclinical animal study to test new markers and assays, according to the announcement on July 30th. After submitting these results to the FDA, the hold was lifted, and the company has been cleared to begin administering the treatment to human patients.
"Our goals for the application of GRNOPC1 in subacute spinal cord injury are unchanged," Okarma said — "to achieve restoration of spinal cord function by the injection of hESC-derived oligodendrocyte progenitor cells directly into the lesion site of the patient's injured spinal cord."
Read more: Embryonic stem cell trial back on – The Scientist – Magazine of the Life Sciences http://www.the-scientist.com/blog/display/57605/#ixzz0vaKKKYSO


text:
Mission Creek
Terrible picture of one of the armory's lowest levels. On the right you can see Mission Creek flowing with some small carved out channels for water to run through.
This room was really long and apparently was used as firing range.
789 views
0 faves
0 comments
Taken on April 18, 2008

subset: commoncrawl


text:
More From Sedona
Earth to Cyberland...:-) I wanted to share a few more images I captured in Sedona AZ. The sky was really awesome as the Monsoon Season rolled on. I hope all is well out there...give me a buz if you want to talk photography.
Devils Bridge SedonaA hike well worth the effort
No comments posted.
Recent PostsNova Scotia, Skyline Trail Shooting the South Tufa and Milky Way at Mono Lake, California Greek Islands Eureka Dunes, Death Valley Maui Mammals Saguraros of Cave Creek AZ Summit of Brown Mountain with my Phantom 2 California gets some well needed rain! A Fishy Friend ImageBrief Photographer of the Week
January February March April May June July August September October November December


text:
REM Dead Letter Office 1987 FLAC h33t Kitlope
Download FREE And Anonymously
Torrent info
Name:REM Dead Letter Office 1987 FLAC h33t Kitlope
Total Size: 417.22 MB
Magnet: Magnet Link
Seeds: 0
Leechers: 0
Stream: Watch Full Movie @ Movie4u
Last Updated: 2014-06-01 02:04:46 (Update Now)
Torrent added: 2008-07-03 03:34:16
Torrent Files List
Dead Letter Office.cue (Size: 417.22 MB) (Files: 24)
Dead Letter Office.cue3.61 KB
R.E.M. - Dead Letter Office - 01. Crazy.flac19.05 MB
R.E.M. - Dead Letter Office - 02. There She Goes Again.flac18.00 MB
R.E.M. - Dead Letter Office - 03. Burning Down.flac29.98 MB
R.E.M. - Dead Letter Office - 04. Voice of Herold.flac30.16 MB
R.E.M. - Dead Letter Office - 05. Burning Hell.flac26.39 MB
R.E.M. - Dead Letter Office - 06. White Tornado.flac12.65 MB
R.E.M. - Dead Letter Office - 07. Toys in the Attic.flac16.74 MB
R.E.M. - Dead Letter Office - 08. Windout.flac14.18 MB
R.E.M. - Dead Letter Office - 09. Ages of You.flac26.40 MB
R.E.M. - Dead Letter Office - 10. Pale Blue Eyes.flac18.38 MB
R.E.M. - Dead Letter Office - 11. Rotary Ten.flac11.73 MB
R.E.M. - Dead Letter Office - 12. Bandwagon.flac15.04 MB
R.E.M. - Dead Letter Office - 13. Femme Fatale.flac17.99 MB
R.E.M. - Dead Letter Office - 14. Walters Theme.flac10.70 MB
R.E.M. - Dead Letter Office - 15. King of the Road.flac19.18 MB
R.E.M. - Dead Letter Office - 16. Wolves, Lower.flac27.33 MB
R.E.M. - Dead Letter Office - 17. Gardening at Night.flac23.42 MB
R.E.M. - Dead Letter Office - 18. Carnival of Sorts (Box Cars).flac24.72 MB
R.E.M. - Dead Letter Office - 19. 1,000,000.flac19.45 MB
R.E.M. - Dead Letter Office - 20. Stumble.flac35.73 MB
R.E.M. - Dead Letter Office.log9.22 KB
R.E.M. - Dead Letter Office.m3u1.77 KB
tracked_by_h33t_com.txt0.02 KB
Announce URL:
Torrent description
File Type: FLAC Compression 6
Cd recorder: Plextor PX-716SA
Cd Ripper: EAC 0.99 prebeta 3
EAC Log: Yes
EAC Cue Sheet: Yes
Tracker(s): http://www.h33t.com:3310/announce; http://tpb.tracker.thepiratebay.org:80/announce; http://inferno.demonoid.com:3419/announce
Torrent Hash: 3CCBA1680BA6F1BA1A21C82ACD38D936683A725C
File Size: 417 Mb
Year: 1987
Label: IRS Records
Please help seed these FLACs!
From Wiki:
R.E.M. is an American rock band formed in Athens, Georgia, in 1980 by Michael Stipe (lead vocals), Peter Buck (guitar), Mike Mills (bass guitar), and Bill Berry (drums and percussion). R.E.M. was one of the first popular alternative rock bands, and gained early attention due to Buck's ringing, arpeggiated guitar style and Stipe's unclear vocals. R.E.M. released its first single, "Radio Free Europe", in 1981 on the independent record label Hib-Tone. The single was followed by the Chronic Town EP in 1982, the band's first release on I.R.S. Records. In 1983, the band released its critically acclaimed debut album Murmur, and built its reputation over the next few years through subsequent releases, constant touring, and the support of college radio. Following years of underground success, R.E.M. achieved a mainstream hit in 1987 with the single "The One I Love". The group signed to Warner Bros. Records in 1988, and began to espouse political and environmental concerns while playing large arenas worldwide.
By the early 1990s, when alternative rock began to experience broad mainstream success, R.E.M. was viewed as a pioneer of the genre and released its two most commercially successful albums, Out of Time (1991) and Automatic for the People (1992), which veered from the band's established sound. R.E.M.'s 1994 Monster was a return to a more rock-oriented sound. The band began its first tour in six years to support the album; the tour was marred by medical emergencies suffered by three band members. In 1996, R.E.M. re-signed with Warner Bros. for a reported US$80 million, at the time the most expensive recording contract in history. The following year, Bill Berry left the band amicably, with Buck, Mills, and Stipe continuing as a three-piece. Through some changes in musical style, the band continued its career into the next decade with mixed critical and commercial success. In 2007, the band was inducted into the Rock and Roll Hall of Fame.
Dead Letter Office is a rarities and B-sides collection by R.E.M., released in 1987. The album effectively mops up many of the additional recordings R.E.M. made pre-Murmur to Lifes Rich Pageant that were outtakes or released as flip sides to their singles internationally. Many of the tracks are favorite cover versions indicating the band's disparate influences and musical tastes, including three Velvet Underground covers, and songs by Pylon, Aerosmith and Roger Miller.
Guitarist Peter Buck composed wry, self-deprecating (and, in one instance, apologetic) liner notes to the songs on Dead Letter Office.
The album was initially issued as a 15-song collection on vinyl and cassette, but when its CD edition appeared (now the only available edition of Dead Letter Office) the Chronic Town EP from 1982 was added to it.
Dead Letter Office originally reached #52 in the U.S. and #60 in the UK.
All songs written by Bill Berry, Peter Buck, Mike Mills and Michael Stipe, except as indicated.
Post side
"Crazy" (Randy Bewley, Vanessa Briscoe, Curtis Crowe, Michael Lachowski) – 3:03 B-side of "Driver 8" 7 inch single & "Wendell Gee" 7 & 12 inch singles
"There She Goes Again" (Lou Reed) – 2:50 B-side of I.R.S. "Radio Free Europe" 7 inch single
"Burning Down" – 4:12 B-side of "Wendell Gee" 7 & 12 inch singles
"Voice of Harold" [1] – 4:24 B-side of "So. Central Rain" 12 inch single
"Burning Hell" – 3:49 B-side of "Cant Get There From Here" 12 inch single
"White Tornado" – 1:55 B-side of "Superman" 7 & 12 inch singles
"Toys in the Attic" (Steven Tyler, Joe Perry) – 2:28 B-side of "Fall On Me" 12 inch singles
Script side
"Windout" (Jerry Ayers, Berry, Buck, Mills, Stipe) – 1:58 from Bachelor Party soundtrack
"Ages of You" – 3:42 B-side of "Wendell Gee" 7 & 12 inch singles
"Pale Blue Eyes" (Reed) – 2:53 B-side of "So. Central Rain" 12 inch single
"Rotary Ten" – 2:00 B-side of "Fall on Me" 7 inch single
"Bandwagon" (Berry, Buck, Mills, Lynda Stipe, M. Stipe) – 2:16 B-side of "Cant Get There From Here" 7 & 12 inch singles
"Femme Fatale" (Reed) – 2:49 B-side of "Superman" 12 inch single
"Walters Theme" – 1:32 B-side of "So. Central Rain" 7 inch single
"King of the Road" [2] (Roger Miller) – 3:13 B-side of "So. Central Rain" 7 inch single
CD Bonus tracks (Chronic Town EP)
"Wolves, Lower" – 4:10
"Gardening at Night" – 3:29
"Carnival of Sorts (Boxcars)" – 3:54
"1,000,000" – 3:06
"Stumble" – 5:40
Enjoy :)
related torrents
Torrent namehealth leech seeds Size
REM Document 1987 FLAC h33t Kitlope0 0 264.76 MB 0
Eric B and Rakim Paid In Full 1987 [FLAC] [h33t] Kitlope1 9 278.19 MB 0
REM Automatic for the People [FLAC] [h33t] Kitlope1 2 315.51 MB 0
REM Out of Time 1991 [FLAC] [h33t] Kitlope4 3 293.05 MB 0
Inxs Kick 1987 [FLAC] [h33t] Kitlope3 9 252.26 MB 0


text: The Unplanned Cabaret – Riding the wave of the cabaret revival, the Unplanned Cabaret brings you all the sparkling dresses and fake eyelashes, all the smooth voices and faded glamour, but with the added delight that everything you see is improvised right in front of you. Cabaret that can never be repeated. The UK's best musical improvisers take turns to croon a love song and belt out a ballad, with maybe just a little poetry and burlesque thrown in for good measure.


text:
So I am back.
If you havent seen it already, I have a new webpage online. It is accessible via www.ursproductions.com
My Blog posts will also show there, so you can either read my Blog on my webpage, or here.
I am currently in the middle of my Bachelors studies project, so time is short, as always. Its about creating a 3D Visualization of an real existing interior.
The final render of the interior looks like this:
I have to finish the project on the 25th May. There is still a lot of work to do. I will try to keep you posted.
I will crate a complete workflow tutorial on how I achieved this visualization.
So subscribe to this blog to be up to date on recent news.


text:
quote:Hi, dear bro Jim from Scotland!
Real Name - Zoran Zekovic
Nationality - Serbian
Home Town - Novi Sad (maybe you know something about EXIT festival?)
When/how did you first hear ABB - 1974 - I was 12 and that was a double LP, of course, Live at FE
Black Hearted Woman is a my favorit!
Seen ABB? - Never!!! But I have more than 50 different CDs of ABB and my only wish is to go next year to Beacon!
quote:Hey geordielad, I went to school in Alnwick!
quote:Dear bro Danis, we have to thinking about our tour to USA (NY, Beacon)! It will be nice to drink beer (maybe we'll find Mythos) together again, but this time in USA!!!
Dear bro Dave, send me your address and you will get "Great Woods"!


text:
Police cordon off the cafe where Mr Ledinh was shot.
A MAN has been charged with murder after being arrested by Homicide Squad detectives investigating the shooting murder of Ho Ledinh at Bankstown last month.
Just after 3.35pm on Tuesday, January 23, 65-year-old local solicitor, Ho Ledinh, was shot while sitting at a cafe at Bankstown City Plaza.
Despite the efforts of police, NSW Ambulance Paramedics, and members of the community, the Mr Ledinh died at the scene.
Detectives from the State Crime Command's Homicide Squad, and Bankstown detectives, established Strike Force Eugene to investigate the circumstances surrounding the shooting.
Just before 10am today (Tuesday, February 13), a 38-year-old man was arrested by Strike Force Eugene investigators at Sydney International Airport as he boarded a plane for Bali.
He was taken to Mascot Police Station and charged with murder.
Police will allege in court the man approached Mr Ledinh and shot him a number of times at close-range.
The man was refused bail to appear at Central Local Court today (Wednesday, February 14).
Strike Force Eugene detectives also executed a search warrant at a home unit at Hammondville, where they have seized items relevant to the investigation.
Investigations into the circumstances surrounding the shooting are continuing, and further arrests are expected.


text:
Motherhood is hard, isn't it? Not only do you expend every last ounce of energy trying to do this job to the very best of your ability, but you're also trying to navigate the millions of messages flying around about motherhood.
You hear motherhood is enough, and then you hear that you should be more than just a mom. You hear motherhood is a high and holy calling, but it's not who you are. You teach your children that family is the most important thing, but then wonder if you've made it an idol.
What is the truth?
When we read or hear something that challenges our motherhood role, it cuts straight to our core. It immediately triggers that fight-or-flight response: we either rise in anger to defend our decisions to the death, or retreat to our safe little corner, lick our wounds, and soothe our hurting heart.
I work full-time outside the home. That comes with its own unique set of challenges. And I'll be honest, I'm particularly sensitive to commentary that criticizes my choices or insinuates that I'm not as good a mother as those who stay home. I feel my blood pressure leap and I sense myself getting defensive. And I want to find refuge in my other working-mom friends who assure me that we can have it all and do it all and that I'm the very best mother that I could possibly be to my children. Hearing that feels better than hearing I am failing.
Whether you work or stay home, I'm sure you can relate. Anything that challenges our choices as mothers is felt deeply. And painfully.
So knowing that this experience is common among all mothers regardless of their journey, I'd like to propose something – the idea that in those painful moments that challenge us as mothers, there is something of value. It is a grain of truth.
And sometimes, the truth hurts.
But we'll never recognize that teeny particle of truth if all we do is dismiss the thought, retreat after a challenging moment, and surround ourselves with messages that feel good to our mama-soul. Instead, we need to stay there in those challenging moments. Hang out a bit, honor the discomfort, and identify exactly why that challenge makes us uncomfortable.
Perhaps it's because the notion was completely off base and we're just frustrated with the perpetuation of ill-informed motherhood stereotypes.
But perhaps it's because it's touching a tender spot inside of us that we already know needs to be acknowledged but we hadn't had the courage to admit or thoroughly explore.
Yes, I work full-time but no, I don't love my kids any less than any other mother does.
You're right, I don't spend as much time with my kids as I should. Maybe I need to figure out how to give my kids more undivided attention.
Yes, my house IS messy and I admit that I could probably spend less time watching TV and more time cleaning.
No, I'm not lazy. My house is not tidy because I was busy playing with my kids today.
Yes, I could find ways to slower the pace of life around here to spend more time with my husband. Busy does not always equal better.
It's true, perhaps I discipline more out of anger and frustration than out of love.
No, after thinking about it I really don't feel called in this moment to take on any more things than I'm already doing.
Yes, you're right – I DO feel like we're insulated and I want to be more involved with serving others, but I'm not sure how.
My child is struggling with behavior and yes, I could probably be more consistent in the way I deal with it.
After weighing it, no, I'm really not concerned about my child's behavior.
Growth rarely comes without pain. Without discomfort. And here at allmomdoes, we want to encourage you. But we also want to challenge you. Because none of our parenting journeys are – or ever will be – the same. We don't know what's best for you and your kids.
But you do.
Unless you let yourself live in those moments of discomfort and really reflect on that small voice inside yourself, you might miss those opportunities for growth. This isn't about mom-guilt and trying to match the façade everyone else seems to put on.
It's about helping each other to be better.
Not perfect, not more, not the best.
Just better.
Have you ever felt like retreating in a painful motherhood moment but instead turned it into an opportunity for growth? Tell us about it!


text:
Villa Blue Karma Suite
Honeymoon 1 Bedroom Suite Villa in Seminyak,Seminyak -Reference ID: VSRH25
This opulent honeymoon 1 bedroom suite villa in Seminyak is located within a one of a kind lifestyle resort in the heart of Bali activities and happenings in Seminyak. The resort is within walking distance to shops, restaurants and to the beach. Artistic creativity, comfort, ethnic design and a flourishing garden have come together to make this location a Seminyak vacation paradise.
The site has been strongly influenced by Alexa Aguila Genoyer's artistic touch which you'll discover right from the lobby through her colorful paintings in contrast with the sobriety of the chosen materials such as teak, lava stone. She has succeeded in creating a very special ambiance that makes modernity serve tradition, nestled into the abundant greenery. Sobriety and the refinement of the decoration lend to the site that special soothing touch, an invitation to relax body and soul in the spiritual heart of Bali.
This private modern one bedroom villa smartly designed in rustic style, with atmosphere accents like rough wood and a wide array of wood carvingd from throughout the Indonesian archipeligo.
Ideally located in upscale resort in the heart of Seminyak, this villa is one of a nine-villa retreat, centrally situated, with many attractions and the best restaurant such as Made Warung, Mozzarella, Gado Gado restaurant, La Plancha Beach Lounge within easy walking distance. Also many Balinese shops, luxury spas, chic boutiques, Bintang supermarket and Seminyak beach are only a short stroll from your front door.
The estate also boasts a lovely cafe-side open plan restaurant serving a creative range of both Western and Indonesian cuisines.
Low season: USD 150 nett/night min. stay 3 nights stay
Jan 14 Jun; 16 Sep 17 Dec
High season; USD 181 nett /night min. stay 5 nights stay
15 Jun 24 Jul; 21 Aug 15 Sept; 18 Dec 23 Dec; 03 Jan 08 Jan
Peak season: 218 nett /night min. stay 7 nights stay
25 Jul 20 Aug; 24 Dec 2 Jan
* Children under 5 years Free
• welcome drink and chilled purified napkin upon arrival
• daily buffee breakfast for 2 person
• Complimentary scheduled buggy drop off service to seminyak beach
• Serene beautiful free form outdoor sharing pool
• Daily breakfast for 2 person
• One en-suite bedrooms with air-conditioning
• One private en-suite bathroom with rain shower
• TV & DVD player
• Cable TV channel
• Mini Bar
• Chic Restaurant and Bar serves Asian and Western food
• Free Wi-Fi, parking, and beach shuttle Seminyak area only
Ref-ID: VSRH40
Charming Three Bedroom Villa 200m from Double ...Seminyak Area
Ref-ID: VSRH39
Luxury Villa 3 Bedroom Beachside SeminyakSeminyak
Ref-ID: VSRH38
Beachside 3 Bedrooms villa in SeminyakSeminyak
Ref-ID: VSRH37


text:
Dog-friendly Wells Hotels & WiFi
Wells Hotels & WiFi
The Bow-wow FactorResident dog Camber will help new arrivals settle in. For a quick stroll, walk…Price (per night) from:Explore and book£115.00
Two-Night Gourmet Dog Lovers Escape: From £280
Includes: Five-course tasting menu for two . Bed and breakfast both mornings . Half bottle of wine
- 1


text:
Afraid takes its title from the eponymous song by Nico. It is elusive, melancholic and suggestive. On the occasion of the 15th anniversary by WArd/waRD and the accompanying festivities Marc VAnrunxt suggested to make a solo for Ann Van den Broek, under the slogan: ' Watching Ann Van den Broek '. Afraid is the result of a series of brief encounters in the studio between the two choreographers. They are no strangers to each other. Since Co (te) lette (2007), Marc Vanrunxt is involved as an outside eye during almost every creation process by Ann Van den Broek. They share a fascination with the dark, the repetitive and the elusive.
Choreography: Marc Vanrunxt, Ann Van den Broek
Dance: Ann Van den Broek
Music: Nico, Scott Walker, Body/Head, Ella Fitzgerald
Licht: Stef Alleweireldt
With the support of the Flemish Community and the Fonds Podiumkunsten (NL)
Production: WArd/waRD, Kunst/Werk
- 05/11/15 Rotterdamse Schouwburg- Première
- 27/11/15 CCbe, Antwerpen
- 21/01/16 Verkadefabriek, Den Bosch (NL)


text:
To check the current term, go to onRecord> Performance> Grading> Generate Academic Performance and the term that the term filter defaults to is the current term.
If you forgot to generate performance and performance is based on a grade average then you can run the Grading Report: GPA Term Ranking. (onRecord > Dashboard > Reports)
1. Select Grading Reports
2. Run the GPA Term Ranking Report
3. Select the relevant filters. Formula in this report means Grade Average.