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Homemade Skin Care Recipes
Leons Anti-aging Beauty Secrets
Leons Anti-Aging Beauty Secrets provides useful tips for women on anti-aging and skin care. This book reveals interesting ancient beauty secrets, talks about anti-aging diet, and provides easy-to-make natural recipes for home skin care. Learn how to use Essential and Carrier Oils to make your own Anti-aging Serums that rejuvenate, revitalize and brighten your complexion. Make your own Alpha Hydroxy Facial Masks to deal with Dull, Blotchy, Lifeless and Wrinkled Skin. Dont you want to know what women in other countries have been using for generations to keep themselves young and gorgeous? Discover the Anti-aging Secrets of women across the Globe. Learn how these easy Facial Exercises can reduce your Laugh Lines, Puffy Eyes, Wrinkles and improve your overall Skin Tone. Make Your own Eyelash Growth Serum using some Carrier Oils and get Longer, Darker and Thicker Eyelashes in less than a month. Learn Gemstone Therapy For Aging Skin and Make Your Own Gemstone Elixir. More here...
Leons Antiaging Beauty Secrets Overview
Contents: Ebook
Author: Lleaon Rao
Official Website: leonsantiagingbeautysecrets.com
Price: $21.00
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Rejuvenating Skin Care Recipes
The Naturally Skinsational eBook shares the simple secrets that will teach you how to use the potent rejuvenating properties of common all natural ingredients to effectively rejuvenate your skin. Consider all the benefits of making your own skin treatments using all natural recipes: Gives your aging skin effective anti-aging treatments and defense against damage using the science of herbal lore to proactively address the symptoms of aging skin including fine lines, wrinkles, age spots and sagging skin. Provides your skin with all-natural rejuvenating properties of herbs that best combat degeneration by stimulating healing, collagen production, and offer powerful antioxidant protection against further signs of aging, skin damage and deterioration. Nourishes your skin with powerful natural antioxidants and nutrients that stimulate cell regeneration. Saves you ridiculous amounts of money on store bought skin treatments. Uses common ingredients found right in your own kitchen. Quick and easy skin care recipes that use ingredients with proven natural anti-aging attributes. Gives you piece of mind that your skin treatments are made with quality fresh ingredients. Provides a deep sense of satisfaction that your homemade skin care products have maximized the potency of natural ingredients. More here...
Rejuvenating Skin Care Recipes Overview
Contents: Ebook
Author: Sue Dolan
Official Website: www.skincareresourcecenter.com
Price: $9.95
Skin Care
Organ, covering the entire body in a four-layer sheath. Like all organs, skin serves specific purposes that contribute to overall physical well-being. Limited ability, for example, to sense potential dangers to the skin or to turn or position oneself, can result in damage to the skin and cause it to break down. Proper skin care is essential to maintain function and prevent breakdown of this vital organ. An understanding of basic anatomy, skin functions, and proper care will allow you to prevent and manage skin problems.
Additional Vol Umes In Prepara
There is little commonality in the scientific methods, processes, and formulations required for the wide variety of cosmetics and toiletries in the market. Products range from preparations for hair, oral, and skin care to lipsticks, nail polishes and extenders, deodorants, body powders and aerosols, to quasi-pharmaceutical over-the-counter products such as antiperspirants, dandruff shampoos, antimicrobial soaps, and acne and sun screen products.
Multifunctional Cuticle Treatments
The primary function of cuticle treatment products has changed somewhat over the years. Thirty years ago the emphasis was limited to cuticle removers that aided in pushing back or even dissolving the part of the cuticle, which extends over the base of the nail. Ingredients used for this purpose were very harsh and included potassium hydroxide at a high level. While these products still exist, the primary function and emphasis have become broader and more practical. Cuticle products are now positioned to treat most of the skin tissue that immediately comes in contact with the fingernail. Our own line of nail care products includes several cuticle treatments, none of which contain potassium hydroxide. This change of emphasis offers the consumer products that are more helpful in dealing with real conditions, including hangnails, broken irritated skin where hangnails have been removed, and the thick accumulations of dry skin that form around the sides of the nail.
Aneurysmal Subarachnoid Hemorrhage
SIADH involves the release of ADH, despite a low serum osmolality. It has an average onset at 8 days and lasts 3-9 days. Patients have a normal skin turgor and blood pressure, a normal or decreased hematocrit, hyponatremia with serum hyposmolality and a urine osmolal-ity greater than serum osmolality. Renal and adrenal functions are normal, as is urinary excretion of sodium. Hyponatremia of SIADH is generally associated with normovolemia from ADH-induced free water retention in the kidney.
Multifunctional Nail Polish Remover
A wide range of moisturizing ingredients that provide conditioning and moisturization of the nail and cuticle can be included. Ingredients used to moisturize and condition the nail and cuticle are chosen based on their solubility in the active solvent. Almost any therapeutic ingredient useful in other skin care products can be used in nail polish remover. While it is customary to use moisturizers and conditioners that are inexpensive because nail polish remover is typically one of the lowest priced items in the beauty department, it is prudent to use one that provides the maximum effectiveness at the lowest concentration. This strategy provides maximum treatment with the least negative impact on product performance. The test method that follows allows one to create a balance between removal efficiency, cost, and treatment of nail and cuticle.
Plateletderived growth factor
Normal skin appears to be devoid of PDGF receptors. Animal studies illustrate that rapid expression of both a and P receptor subunits is induced upon generation of an experimental wound (e.g. a surgical incision). Receptor expression is again switched off following re-epithelialization and complete healing of the wound.
Quantitative Absorption Data
In experiments that measured the reverse of percutaneous absorption, the potassium flux from the inside of normal skin to water on the stratum corneum was 3.5 ( 3.6) X 10 9 mol cm2 sec (Table 2) (18). Removing the stratum cor-neum doubled the potassium flux. The brief duration of these experiments made it impossible to determine a reasonable permeability coefficient.
Sellarsuprasellar tumours pituitary adenoma
'Adult GH deficiency syndrome' -weight gain, loss of libido, fatigue Amenorrhoea, sterility, loss of libido Glucocorticoid and androgen deficiency, muscle weakness and fatigue Secondary hypothyroidism -sensitivity to cold, dry skin, physical and mental sluggishness, coarseness of hair Failure of lactation
Stage 2 preclinical HIV infection
Although viral titres fall in the circulation at this time there is significant and persistent virus replication within lymph nodes and spleen. The clini-414 cally latent period may last 8-10 years and circulating CD4 T-cell count remains normal for most of this period. However, there is a delayed, gradual but progressive fall in CD4 T lymphocytes in most patients, who may remain asymptomatic for a prolonged period despite modest lym-phopenia. A number of minor skin problems such as seborrhoeic dermatitis are characteristic of the end of the latent phase.
Nonmalignant Skin Disease
The most common and debilitating skin problems arise from the long-term use of glucocorticoids. The manifestations include striae, friable skin, ecchymosis, acne-form rash and cushingoid features. In addition, cyclosporine may cause thickening of the skin, hypertrichosis, gingival hyperplasia, epidermal cysts, pilar keratosis, and folliculitis. Treatment includes reducing the dosage of these medications to the lowest level necessary to maintain immunosuppression and topical measures.
Aortic and visceral revascularization
Embolization to distal sites, particularly in aortic surgery, can occur at various stages during the procedure, releasing atherosclerotic and thrombotic debris to the distal circulation. This becomes most evident in the foot, with patchy areas of cyanosis or necrosis. Prevention is of paramount importance, and treatment should be expectant, with foot cradles for protection and skin care for prevention of infection. In cases where viability of the foot is a concern, thromboembolectomy with a Fogarty balloon catheter, followed by infusion of urokinase, may be an alternative.
Sympathomimetic syndrome
May be difficult to distinguish from anticholinergic syndrome. Sweating and normal to hyperactive bowel sounds are associated with sympathomimetic overdose, whereas anticholinergic toxidrome manifests with dry skin and diminished bowel sounds.
Clinical Implications and Perspectives
In conclusion, aging is associated with many skin microvasculature changes, all with a negative influence on tissue nutrition, which can explain the increased fragility and vulnerability of elderly skin to the different noxae and to the environment stress. Thermoregulatory adaptive mechanisms are also affected, resulting in a reduced capability to cope with both heat and cold stress. 9. Smith, L. (1989). Histopathologic characteristics and ultrastructure of aging skin. Cutis 43, 414-424.
Prevalence Of Overweight And Obesity
Obesity is now known to be a major contributor to the global burden of disease.3 Obesity is associated not only with some nonfatal but debilitating health problems, such as respiratory difficulties, chronic musculoskeletal problems, skin problems, infertility, sleep apnea, and poor mental health, but also more life-threatening problems, including hypertension, type 2 diabetes, heart disease, stroke, some types of cancer.315 Obese people have higher mortality from all causes 16-19 more than 280,000 deaths annually have been attributed to obesity among U.S. adults.20 In Europe, this number is at least 279,000 deaths, of which 175,000 are attributable to obesity and 104,000 to overweight.21 Furthermore, a large decrease in life expectancy is observed among obese individuals, especially among younger adults.22,23 Severely obese children and adolescents have lower health-related quality of life24 and early-onset obesity has been suggested as a risk factor for morbidity and mortality later...
Managing Consumers Expectations Can Also Be Challenging
Sometimes promised results are so long in coming, or learning proper use is so time-consuming, that consumers give up. Products that take weeks or months to show their multifunctional benefits often are abandoned before the formulations have had a chance to achieve results. Countless bottles of skin care products rotate through consumers' cabinets as any subtle wrinkle or pore reduction goes unnoticed. People move on to the next possibility, hoping that it can work sooner, or even at all. Patience levels need to be queried in consumer research studies. Super-high-margin Rembrandt toothpaste succeeded in spite of itself because consumers perceived that, over time, it was working to whiten their teeth better than other toothpastes. Dentists, however, agreed that there was actually no superior benefit. Researchers need to determine the specifics about how the consumer thinks the MFP will perform, as well as to assess their levels of expectations.
Key Points Of Inquiry
Sometimes, when marketers get it right, just one added ingredient can start a market boom. For example, there has been significant growth in industries such as skin care products because, for example, interest in anti-aging and sun protection have driven the development of new products that incorporate alphahydroxy acids (AHAs) and sunscreens. In recent years, over a thousand new products are launched annually, more than twice as many as a decade ago. AHAs have been responsible for much of this impressive growth. Marketers need to learn more and manage data better to get to these sweet spots.
Clinical Radiological And Pathologic Characteristics
Venous malformations (VMs ) are the most common intramuscular vascular anomalies the patient is usually a child or an adolescent, sometimes a young adult, brought to consultation for localized pain, soft-tissue swelling, and intermittent functional impairment. Pain develops during physical activities (6) but also in the morning on waking up and during cold rainy weather. Physical signs include a tender mass under a normal skin the situation is distinct clinically from an intramuscular VM of the extremities trunk with blue skin involvement (20) , no local inflammation, no pulsation, no bruit, and no general symptoms. If lower limb pain was present for several years, atrophy of the limb may develop as a consequence of the limitation of physical activities. Limitation of joint motion may also occur.
The Multidisciplinary Team
The nurse's main responsibilities are to work with client and family to increase independence in personal care with a 24-h approach advice regarding skin care, diabetes, continence and general health promotion liaising with district nurses and general practitioners, teaching self-help strategies dietary advice understanding medication methods of lifting and handling.
Xavier Intes PhDa Britton Chance PhD ScDb
Light absorption in tissue originates from many different analytes. The main relevant chromophores are oxyhemoglobin and deoxyhemoglobin, melanin, water, lipids, porphyrins, NADH, flavins, and other structural components. In the NIR spectral range, however, the chromophores exhibiting significant extinction coefficients can be limited to four as shown in Fig. 1 (melanin is overlooked because of its confinement to the normal skin) (1) oxyhemoglobin, (2) deoxyhemoglobin, (3) water, and (4) lipids. NIR interrogation of tissue at multiple wavelengths correlated with appropriate photon propagation models provides the average or local quantitative concentrations of these compounds. Consequently, NIR optical techniques allow noninvasive monitoring of the metabolic activity of deep tissue through the hemoglobin concentration and oxygen saturation. This monitoring, combined with the inexpensive cost of instrumentation, opens many potential medical applications to NIR techniques.
Normal Flora of the Skin
The skin represents a distinct ecological habitat, analogous to a cool desert, compared to the warm, moist tropical conditions that exist in other body systems. Large numbers of microorganisms live on and in the various components of the normal skin. For example, depending on the body location and amount of skin moisture, the number of bacteria on the skin surface may range from only about 1,000 organisms per square centimeter on the back to more than 10 million in the groin and armpit, where moisture is more plentiful. The numbers actually increase after a hot shower because of increased flow from the skin glands where many reside. Most of the microbial skin inhabitants can be categorized in three groups diphtheroids, staphylococci, and yeasts (table 22.1, and see figure 22.1). Although generally harmless, skin organisms are opportunistic pathogens, meaning that they can only cause disease in people with impaired body defenses. Table 22.1 Principal Members of the Normal Skin Flora...
Reservoirs of Infectious Agents in Hospitals
Many hospital-acquired infections originate from the patient's own flora. Nearly any invasive procedure can transmit microorganisms that are part of the normal flora to otherwise sterile body sites. When intravenous fluids are administered, for example, Staphylococcus epidermidis, a common member of the normal skin flora, can potentially gain access to the bloodstream. While the immune system can usually readily eliminate these normally benign organisms, the underlying illness of many hospitalized patients compromises their immunity and they can develop a bloodstream infection. Patients who undergo intestinal surgery are prone to surgical site infection by their normal bowel flora. Similarly, patients who are on cer- Just as urinary catheters can introduce bacteria into the bladder, intravenous (IV) catheters can introduce micro organisms into the bloodstream. This can happen when normal skin flora colonize the tip of an indwelling catheter or when environmental organisms contaminate...
Essential Fatty Acid Requirements
Columbinic acid (C18 3n-6, 9, 13 cis, cis, trans), found in the seed oil of the columbine, Aquilegia vulgaris, and dihomocolumbinic acid (C20 3n-6, 9, 13 cis, cis, trans) have been used to differentiate the roles of EFA as structural components in biomembranes versus their roles as eicosanoid precursors ( 115). Neither columbinic acid nor dihomocolumbinic acid can be converted to PG however, columbinic acid can be incorporated into membrane PL in contrast to dihomocolumbinic acid. As EFAD results in decreased tissue concentrations of C20 4n-6, EFAD symptoms are worsened further by dietary addition of dihomocolumbinic acid. Columbinic acid given to EFA-deficient rats, either orally or by topical skin application, efficiently restores their growth rate and normal skin function ( 114). When EFA-deficient rats treated with columbinic acid became pregnant, however, they died of inadequate labor during parturition, since uterine labor depends on normal PG biosynthesis ( 116).
Skin Microcirculation in the Elderly
Age-related structural alterations in the skin have been well documented by histologic and ultrastructural examination of skin biopsy specimens from younger compared to older people 9 . The fine, regular epidermal surface pattern changes to coarser and less regular ridges with aging. Epidermal projections into the dermis are retracted and the dermal-epidermal junction is flattened. The dermis becomes thinner, and there are fewer fibrillar collagen and elastic fibers in older skin. A progressive reduction with age in the dermis hyaluronic acid content has been also demonstrated, which could account for some of the most striking alterations of the aged skin, including decreased turgidity, altered elasticity, and less support for microvessels. Basic mechanisms underlying skin aging can be represented by a reduced cellular turnover and a prolonged time to recover after an injury 10 . According to the majority of the experts in this field, the morphofunctional state of skin, to a large...
Kaposis Sarcoma Associated Herpesvirus KSHV or HHV8
In 1994, Chang et al used representational difference analysis (RDA) to search for DNA sequences present in AIDS-associated KS but not in adjacent normal skin. Using this approach, they were able to identify a then unknown human g-herpesvirus in KS tissue, which they called the Kaposi's sarcoma-associated herpesvirus (KSHV) or human herpesvirus 8 (HHV-8) 5 . KSHV belongs to the genus Rhadinovirus, and its genomic structure is most similar to the closely related lymphotropic g-herpesviruses Epstein-Barr virus (EBV), the only other known human her-pesvirus associated with human cancers. Compelling evidence points to KSHV as the infectious etiologic agent for KS (i) Epidemiological studies have established a pattern of KSHV infection that precedes KS development and overlaps with KS risks. (ii) Examination of KS biopsies revealed that KSHV DNA is present in KS tumor (spindle) cells and in endothelial cells lining vascular spaces of KS lesion. (iii) In vitro studies have demonstrated that...
Molecular Control of Skin Angiogenesis
Whereas angiogenesis is a common feature in developing skin during embryogenesis, blood vessels in healthy adult skin are quiescent with the exception of the cyclic expansion of perifollicular vessels during the hair cycle. In normal skin, vascular quiescence is maintained by the dominant TSP-2 expression during embryonic development and in adult tissues is spatially and temporally different from TSP-1. The expression of TSP-2 is downregulated in epithelial squamous cell carcinoma cells, whereas a strong upregula-tion of TSP-2 is found in the mesenchymal stroma during skin carcinogenesis, representing a natural tumor defense mechanism 6 . Mice that are deficient in TSP-2 show increased skin vascularization, enhanced and prolonged inflammatory reactions, and enhanced skin carcinogenesis, confirming the important role of endogenous TSP-2 in the control of skin angiogenesis. Accordingly, genetic overexpression of TSP-2 protects from skin cancer development and inhibits the growth of...
Monocyte Migration To Sites Of Inflammation
CXCL14 BRAK, which selectively recruits circulating monocytes in homeostasis, as well as monocytes activated by prostaglandin E2 (PGE2). CXCL14 breast and kidney-expressed chem-okine (BRAK), which is thought to be made constitutively by normal skin keratinocytes, dermal fibroblasts, as well as lamina propria cells 60 , Monocytes cultured with PGE2 have been shown to gain chemotactic responsiveness to CXCL14 BRAK, while losing responsiveness to CCL2 MCP-1, CCL5 regulated upon activation, normal T cell expressed and secreted (RANTES), and CXCL12 stromal cell-derived factor (SDF) -1 60 , The receptor for CXCL14 BRAK is yet unknown. The authors propose that once monocytes enter sites of inflammation, local secretion of PGE, polarizes monocytes to be responsive to high levels of CXCL14 BRAK.
Can Starving Yourself Affect Rate Of Healing Of Surgery Wounds
Two principal forms exist cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2). Vitamin D2 is obtained from the diet (Table 9.1), in which case it is absorbed, with the help of bile salts, in the small intestine. Vitamin D3 is produced endogenously by keratinocytes in the skin via biosynthesis from 7-dehydrocholesterol upon exposure to ultraviolet light. The epidermis is where the greatest amount of vitamin D production occurs (49). It is conceivable that large cutaneous wounds and scarring impair the process of epidermal vitamin D synthesis (50,51). Burn scar and normal skin adjacent to the wound show a fivefold decrease in the ability to transform 7-dehydrocholesterol to vitamin D3 (51). 5. Shapiro, S.S. and Saliou, C., Role of vitamins in skin care, Nutrition, 2001 17 839-844.
Clinical Manifestations of Hypothyroidism
Succeeding months, especially in severe cases, protuberance of the abdomen, dry skin, poor growth of hair and nails, delayed eruption of the deciduous teeth, and delay in reaching the normal milestones of development (e.g., holding up the head, sitting, walking, and talking) become evident.
Views Regarding the Term Cosmeceutical
An aspect of the cosmeceutical revolution to consider is its reason for being in the first place. Historically, consumer needs and demands have driven the cosmetic market to evolve to this point. Many years ago, a cosmetic or toiletry product was expected to have one simple function. For example, a lotion helped to moisturize dry skin, and a deodorant was used to mask body odors. As consumers increasingly demanded substantially more benefits from cosmetics and toiletries, multifunctional products were born 1,2 . For example, now a moisturizing lotion also may have antiitch benefits, promote skin exfoliation to reduce flakiness, and promote the healing of dry skin by supplying substances essential to maintain the barrier layer function. Most deodorants now are also OTC drugs because they contain antiperspirants to keep underarms dry in addition to masking body odors.
Wound Reepithelialization
Surgeons have long known that a key factor in wound healing is excellent tissue perfusion. Vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and TGF-b are the critical factors involved in wound angiogen-esis. VEGF is expressed at low levels in normal skin but highly upregulated in keratinocytes during wound healing. Angiogenesis appears to be tied to matrix deposition and granulation tissue formation. Application of a neutralizing anti-VEGF antibody to a wound is associated with decreased wound angiogenesis. Conversely, application of topical VEGF increases wound angiogenesis, granulation tissue formation, and wound closure rates 6 . Diabetic wounds are found to have decreased levels of VEGF expression, but demonstrate very high levels of angiopoetin-2, an antiangiogenic protein. Although angiopoetin-2 production in wounds is not unusual during specific phases of wound healing when vessel growth requires destabilizing preexisting vessels, such high levels are...
S Evidence statements
The last review assessed the effects of different types of absorbent product for the containment of urinary and or faecal incontinence. The results indicated favourable outcomes in terms of skin problems, the number of changes, ease of disposal and cost for disposable vs non-disposable body worns.290
An Example of Combination Claims
Another interesting multifunctional skin care product includes a three-in-one product containing san protection factor (SPF) a moisturizer, and skin-lightening performance characteristics. Manufacturers of moisturizing products in general tend to focus on consumer use of moisturizers in regions that are cold and low in humidity. Although dry skin in these climatic regions does indeed present with the usual flakiness, itching, and general consumer discomfort, consumers in regions with hot weather and low humidity present with some different cosmetic skin care needs.
Cornelia de Lange syndrome
Many children are diagnosed at birth or within a few days of birth. They show characteristic features of hypertricosis (hirsutism, synophrys, long eyelashes), facial abnormalities including depressed nasal bridge, ocular anomalies, prominent philtrum, thin lips, anteverted nostrils, a down-turned angle of mouth, bluish tinge around eyes, nose and or mouth, widely spaced teeth, high arched palate, low set ears, micrognathia, and short neck. Limb deformities include grossly malformed upper limbs, small hands and feet with short digits, limitation of extension of elbows, proximally placed thumbs, clinodactyly of fifth finger, a single transverse palmar crease (in about 51 per cent of cases), and webbing of second and third toes. Other anomalies include cryptorchidism and hypoplastic genitalia in males (57 per cent of cases), a small umbilicus (53 per cent of cases), a low-pitched cry, and small nipples (55 per cent of cases). (33) Systemic abnormalities include severe gastrointestinal...
In the opinion of the author, the most exciting achievements in this arena are those in which the cosmetic scientist has been able to elevate the performance of a subfunctionality to a level of such magnitude that it is perceived as creating a new product category. A prominent example, cited many times throughout this chapter, is the two-in-one shampoo. While the likelihood of attaining comparable achievements in the future may be diminished by consideration of the numbers of scientists presumed to have unsuccessfully explored these areas in the past, it is also increased by the significant strides being made on a regular basis in true cosmetic science. Prominent among these are the achievements contributing to truly efficacious skin care.
Benzoyl peroxide
Benzoyl peroxide is first-line therapy for mild acne. It is available over-the-counter. The liquids and creams (Benoxyl) are less irritating and are useful for dry skin. The gel (Benzagel, Persa-Gel) is more irritating but more effective for oily skin. Mild redness and scaling occurs during the first week. It may irritate the skin, bleach the clothes, and inactivate simultaneously applied tretinoin and other anti-acne products.
Microcheck 222
The normal skin flora are important because they help protect against colonization by pathogens. Occasionally, they cause disease when body defenses are impaired. They are responsible for body odor, and probably contribute to acne. Name and describe the three groups of organisms generally present on normal skin.
Skin Lightening
To evaluate the skin-lightening effect of a product, we perform punch biopsies (2 mm) in the periauricular area of the ear at baseline prior to treatment and following 8 weeks of topical treatment to the contralateral ear region. Following 8 weeks, a second 2 mm punch biopsy sample is obtained from the treated periauricular region of the ear. The skin biopsy specimens are snapped, frozen, and stained with, for example, S-100 monoclonal antibody (which stains specifically for pigment cell and melanin presence when an indirect immunoperoxidase staining procedure is used). Figure 1 shows untreated skin (baseline). One can see dendritic melano-cytes at the basal region of the epidermis (arrows). Figure 2 shows S-100 staining following 8 weeks of topical treatment. Note the subtle yet quantitative reduction in the absolute number of visible pigment-producing melanocytes. Although this difference is not clinically significant to the test subject, t is an objective quantitative observation...
Fact and Fantasy
We reported two decades ago that biomolecules and molecular assemblages such as membranes and proteins can be stabilized in the dry state in the presence of a sugar found at high concentrations in many anhydrobiotic organisms, trehalose.1 We also showed that trehalose was clearly superior to other sugars in this regard.2 This effect seemed so clear it quickly led to wide-spread, and often uncritical, use of the sugar for preservation and other purposes. In fact, an array of applications for trehalose have been reported, ranging from stabilization of vaccines and liposomes to hypothermic storage of human organs.3 Other workers showed that it might even be efficacious in treatment of dry eye syndrome or dry skin in humans.4'5 Trehalose is prominendy listed as an ingredient in cosmetics, apparendy because it is reputed to inhibit oxidation of certain fatty acids in vitro that might be related to body odor.6 Trehalose has been shown by several groups to suppress free radical damage,...
Donna A Chow
NF-kB , an important transcription factor for inflammatory and innate immune responses, is thought to promote keratinocyte viability during their upward migration and differentiation, contributing to spacial control and maintenance of tissue architecture. Kerat-inocytes except those in the granular layer express Fas constitutively, and all appear relatively resistant to the Fas pathway which is dominant in lymphocytes reviewed in 1 , The regulation of keratinocyte survival and death is considered a complex, redundant and highly coordinated process, with stem cell proliferation in the basal layer and terminal differentiation and apoptosis limited to the upper layers of the epidermis reviewed in 1,2 , Apoptotic keratinocytes shrink and are phagocytosed by nearby keratinocytes acting as non-professional phagocytes, while terminally differentiated keratinocytes flatten, form the stratum corneum and eventually are sloughed off reviewed in 1 ,
Book Layout
Chapters 5 and 6 discuss the formulation of multifunctional products for skin care. Chapter 5 provides a detailed look at the development of ingredient mixtures for multifunctionality in skin care products. Methods for choosing appropriate materials and evaluating their effectiveness for various functionalities are given. Similarly, Chapter 6 discusses formulation of multifunctional nail care products and methods for their evaluation. The final three chapters are related to areas that affect the development of multifunctional products but do not specifically deal with formulating. Chapter 11 reviews the techniques involved in developing claims support for multifunctional products. Numerous methods are proposed for both skin care and hair care products. Additionally, an overall strategic approach is proposed for specifically dealing with products of these types. Chapter 12 examines the role of packaging in the development of multifunctional products. Numerous aspects of the package are...
Table 1424
Phillips, T., Demircay, Z., and Sahu, M., Hormonal effects on skin aging, Clin. Geriatr. Med., 17, 661-672, 2001. 96. Phillips, T., Demircay, Z., and Sahu, M., Hormonal effects on skin aging, Clin. Geriatr. Med., 17, 6610-6672, 2001. Thomas, P., Age related changes in wound healing, Drugs Aging, 18, 607-620, 2001. Bolognia, J., Aging skin, Am. J. Med., 98, 99-102, 1995.
Tretinoin Retin A
Fair-skinned patients may begin by applying the 0.025 cream shortly after washing nightly. The quantity of tretinoin applied may be gradually increased as tolerated, and twice-daily applications may be appropriate. The cream is best for dry skin the gel is best for oily skin.
Dapsone and Sulfones
Sulfones, such as dapsone and sulfoxone (Diasone), are well absorbed orally and are widely distributed throughout body fluids and tissues. Peak concentrations of dapsone are reached within 1 to 3 hours of oral administration and have a half-life of 21 to 44 hours about 50 of administered dapsone is bound to serum proteins. The sulfones tend to remain in the skin, muscle, kidney, and liver up to 3 weeks after therapy is stopped. The concentration in inflamed skin is 10 to 15 times higher than that found in normal skin. The sulfones are retained in the circulation for a long time (12-35 days) because of hepatobiliary drug recirculation. The sul-fones are acetylated in the liver, and 70 to 80 of drug is excreted in the urine as metabolites.
The normal skin is generally resistant to invasion by dermatophytes. Some species, however are relatively virulent and can even cause epidemic disease, especially in children. In conditions of excessive moisture, dermatophytes can invade keratinized structures, including the epidermis down to the level of the keratin-producing cells. A keratinase enables them to dissolve keratin and use it as a nutrient. Hair is invaded at the level of the hair follicle because the follicle is relatively moist. Fungal products diffuse into the dermis and provoke an immune reaction, which probably explains why adults tend to be more resistant to infection than children. It also explains why some people develop the allergic id reactions.
Lupus Erythematosus
This feature is sometimes so florid that it produces a pseudoepitheliomatous appearance. The slender downgrowths can also show a tendency to fuse with each other producing an appearance simulating an embedding artefact. Dyskeratotic cells are an occasional feature. There is apoptosis and liquefaction degeneration of the basal cells, sometimes with Civatte body formation. The BMZ may become hyalin-ised and thickened and this is sometimes a notable feature. There is a band-like infiltrate of lymphohistiocyt-ic cells in the superficial corium similar to that seen in lichen planus, but the lower border tends to be less well defined and the infiltrate often extends into the deeper tissues in a perivascular distribution. Reactive follicles may form in the lymphoid infiltrate. In cases of SLE there may be evidence of fibrinoid necrosis in vessels. Direct immunofluorescence of lesional tissue for IgG, IgM or IgA shows a granular deposit in the BMZ of about 75 of cases of...
Multiple Sclerosis
Patients with MS can be studied effectively in the sleep laboratory setting. Similar to other individuals with motor and sensory challenges, these patients may need handicap access and aid in transfer. Technologists should inquire if the patient needs assistance in turning during the night or has other special needs such as requirements for urinary catheterization or skin care needs. Since this disorder can result in hypoventilation and more subtle airway disturbance, these patients should be monitored for end tidal CO2 and nasal pressure.
Daily Life
Plain soap itself generally does not destroy many organisms it simply aids in the mechanical removal of transient microbes, including most pathogens, as well as dirt, organic material, and cells of the outermost layer of skin. Regular handwashing and bathing does not adversely impact the beneficial normal skin flora, which reside more deeply on underlying layers of skin cells and in hair follicles. pathogen, p. 465 normal flora of the skin, p. 535
Think Clean and Green to Flawless Skin
Lets accept the fact: many of us are skin conscious. As much as possible, we wanted to have a fresh, good looking skin. However, many of us failed to recognize that simple steps are the best ways to attain it.


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- excellent location amidst the historic center of Prague
- quick & easy accessibility of many sights
Hotel information (Summer description)
Alternative: Winter description
LocationThe 4*-hotel is located right in the historical center of Prague in Mala Strana, just 60m from Charles Bridge and the Vltava River, close to the stunning Kampa Island. Likewise, Prague Castle and Old Town Square are all within walking distance. The metro station Malostranska is about 300m away.
FacilitiesThe main building dates from the 16th Century, the empire style façade from 1843. The tower of the hotel once served as the official residence of the bishop. The stylish downtown hotel offers beautiful vaulted ceilings, a lobby area with 24-hour reception, a cozy restaurant, a glass-roofed atrium where you can enjoy breakfast and a coffee bar.
Lift is available. Pets free of charge (deposit EUR 100,- per stay).
Payable on spot: limited number of parking spaces on request.
RoomsThe 26 refurbished rooms offer a delightful and cozy ambience. Equipped with shower/toilet, hairdryer, telephone, satellite TV, safe, mini bar, coffee/tea set and Wi-Fi they offer plenty of space for relaxation.
MealsBreakfast buffet.
OtherChild discount/rates in case of 2 full-paying guests: 0-1 year 100%, 2-12 years 50%.
Minimum stay: 1.12.-2.12., 8.12.-9.12., 15.12.-16.12., 22.12.-28.12., 29.3.-2.4., 27.4.-1.5., 10.5.-12.5., 18.5.-21.5. & 31.5.-2.6. 2 nights, 29.12.-1.1. 3 nights.
- free Wi-Fi throughout the hotel
Booking Code: CZPRBH1 DS B/DD B/ ES B/ED B
The displayed hotel information is valid from 1.11.2017 - 31.10.2018

subset: commoncrawl


text:
At the appellate level, Ms. Hively's case was taken on by Lambda Legal , a well-funded pro-gay public interest law firm with long-standing financial ties to left-wing billionaire George Soros's Open Society Foundations. She applied for six full-time promotions between 2009 and 2014, but says she was rejected for all of them, despite her sterling student reviews. "The Constitution assigns the power to make and amend statutory law to the elected representatives of the people", Judge ...
According to Facebook officials, more than 1,000 local people will get the job. Construction of new wind farms in Nebraska will allow the company to power the facility exclusively through wind-generated electricity, according to the governor's office.
The Samsung Galaxy S8 and Galaxy S8+ will run on the company's UI based on Android 7.0 Nougat. You still need the iris scanner and fingerprint reader for that lot. The phone comes with meaningful accessories like the Samsung Dex dock that can turn the smartphone into a desktop computer. According to an unnamed industry source was speaking to The Korea Herald , the S8's facial tracking tech is not secure enough to be used to protect your phone.
Ahead of next week's rollout of the Creators Update, Microsoft is releasing more information on the diagnostic data it collects. Microsoft has had something of a checkered history when it comes to privacy, particularly with Windows 10.
Facebook added that the matter had been resolved earlier by a seven-judge bench and thus there was no point in setting up another five-judge bench. But now once again the same petition has been challenged in the Supreme Court where the petitioner stated that the information shared after 25.09.2016 is not yet protected.
When an image has previously been reported and taken down by Facebook, the company writes, that image will be flagged by the system, and the sharer will be alerted. Specially trained representatives from Facebook's Community Operations team then review reported images and remove them, as well as suspending the account that shared the image in most cases.
It is available in gold, pink, gray, blue and white color variants. Huawei's latest device succeeds the Y6 II that was launched a year ago. The 8 MP camera has a dual flash. Connectivity options include Wi-Fi, GPS, Bluetooth, 3G and 4G. It also a sports bunch sensors including Accelerometer, Proximity, Compass, and Ambient light sensor.
After her runner-up finish, Thompson gave an emotional interview to the Golf Channel , saying that she made an honest mistake and she will learn from it. So you're telling me that's a fair situation as well? During the ANA Inspiration final round, 14-time major victor Tiger Woods took to social media to express outrage at the Thompson decision.
While Apple has not officially announced the price in India of other red iPhone 7 and iPhone 7 Plus variants, based on the pricing of the 128GB red iPhone 7 Plus, it's expected to be the same as other colours. Besides this, Apple introduced Clips , a new app for iPhone and iPad that makes it fun and quick for everyone to create expressive videos. Both iPhone 7 and iPhone 7 plus will be available in 128 GB and 256GB at the price $749 (starting price).
It has been launched with a Champagne Gold color option. Xiaomi has finally taken the wraps off the much talked about Mi Pad 3. It is again backed by a 5MP front-facing selfie snapper. The camera will be available for purchase through starting April 6. It is also IP67 certified, which means it is both water and dust resistant. Connectivity options include Wi-Fi and Bluetooth 4.0.
On Tuesday, Judge Robert Lasnik ordered an injunction on the ordinance after the U.S. Chamber of Commerce sued to block the Seattle rules. The fight over whether Uber and Lyft drivers can unionize is part of a larger conflict over how sharing economy companies treat their workforce.
Honor has opted for rounded corners and a matte aluminum finish on the 8 Pro instead of a glass back, and it feels and looks a lot like the iPhone 7 Plus as a result. The company has a couple of flagship lineages under its Huawei brand name - the smaller Huawei P, the larger Huawei P Plus, and the also-larger Huawei Mate phones.
The handset also houses a decent 3,100 mAh battery. Also at the back is a fingerprint scanner which sits below the dual-camera setup. We're not yet sure whether the phone will be released outside of the Middle East, though it looks too good (by Alcatel standards, anyway) to not be.
None other than Jensen's Aida, who has taken on the moniker of the classic Marvel comics villain Madame Hydra within the universe of the Framework. Along with introducing Madame Hydra, this arc will also see the return of Brett Dalton's late Grant Ward (which comes with an excellent twist we won't spoil).
Shaolin Shuffle will take place in NY and star our regular 4 heroes who will hone their kung-fu skills to fight the funky undead army. The new Infinite Warfare zombie DLC follows its predecessor in its unique offering for Call of Duty players.
Rowe Price . The New York Times published a report Saturday claiming five women had been paid a total of $13 million by O'Reilly and/or 21st Century Fox not to pursue legal action against the show's host. From January 2015 to September 2016, the programme pulled in some US$297 million in ad revenues, according to the research firm Kantar Media. And weight loss and nutrition company Jenny Craig told BuzzFeed News it condemns all forms of sexual assault, but refused to publicly comment ...
The Youtube Go app has been apparently designed from the ground up and the stress is on less data consumption and offline content. Once it gets the green signal, it will be released in other emerging markets. Users will also be able to choose the resolution of the video that they would want to download and share the videos with family and friends. YouTube Go, the YouTube app which lets you save videos for offline viewing, has now launched in beta in India.
On Wednesday, Great Britain officially said its good bye, submitting a six-page letter triggering the EU's Article 50 and the subsequent exit process, which is scheduled to take two years. The document, seen by Reuters, also sets tough conditions for any transition period, insisting Britain must accept many European Union rules after any such partial withdrawal.
Launched today as a U.S. exclusive and expanding over the coming week Twitch claims the initial library will total around 50 games plus in-game content, including Ubisoft's For Honor [sic] and Tom Clancy's Ghost Recon: Wildlands , Telltale Games' The Walking Dead and Minecraft: Story Mode, Hi-Rez Studios' Smite and Paladins, Paradox Interactive's Tyranny, Trion Worlds' Atlas Reactor, Double Fine Productions' Broken Age and Psychonauts , Campo Santo's Firewatch , Jackbox Games' Jackbox ...
ESPN's Adam Schefter , who has the same agent as Romo, broke the story Tuesday. "Houston was at the top of the list of teams that I looked at", Romo said. While chided for his interest in golf and celebrity girlfriends, Romo developed a reputation for toughness. Should a playoff-caliber team encounter an emergency at the position, Romo could be enticed to punt the broadcasting plan.
The Cefprozilmarket analysis is provided for the global market including development history, competitive landscape analysis, and major regions' development status. Finally, the Aluminum-Doped Zinc Oxide Market report ends with a detailed SWOT analysis of the market, investment feasibility and returns, and development trends and forecasts.
Just little things like that where the golf course tempts you to do something. Every player on the PGA Tour wants to win at Augusta , but some are likely feeling a greater sense of urgency than others. "You start to shoot at a few pins. leave yourself in spots you don't really want to". If you don't position yourself well you're pretty much done. Coverage: Watch highlights of the first two days before live and uninterrupted coverage of the weekend's action on BBC Two and up to four live ...
There was a time, not so long ago, when kids could pretty easily rack up a hefty bill with unauthorized in-app purchases on their parents' mobile devices, Mom and Dad only learning about it when they saw their credit card bill. Amazon had argued that the in-app charges were "customer-focused, and lawful, including prominent notice of in-app purchasing, effective parental controls, real-time notice of every in-app purchase, and world-class customer service".
James registered his second straight - and 12th of the season - triple double with 18 points, 11 rebounds and 11 assists. Thompson snapped back at James, exchanging words in the huddle throughout a timeout. However, the Heat have the tiebreaker. Thompson walked away and sat on the scorer's table by himself. "It's just who we are", Lue said. "It's just another game", said Thomas.
Apple is offering the Product (Red) Special Edition iPhones in 128GB and 256GB sizes, starting at $749. You can find out more details about the new Product Red iPhone 7 And iPhone 7 Plus over at Apple at the link below. This special edition iPhone joins the current (PRODUCT) RED lineup. These items are available all year-round on the Apple Store. The lineup also includes the full iPod line of products, Beats Pill+ Portable Speaker, Beats Solo3 Wireless On-Ear Headphones and more.
Jim Ross's return to WWE and his WrestleMania weekend were chronicled in a FOX Sports website story written by Sam Gardner. It's time for the Monday Night Raw after WrestleMania , an event that's become nearly as big as WrestleMania itself.
One notable aspect of the decision to join CBS is that it primarily covers AFC games. Even though Tony Romo never led the Dallas Cowboys to the Super Bowl in his fifteen years playing for them, Tony Romo is still considered one of the best quarterbacks that ever played in the NFL.
Sprinkles , a new iOS camera app from Microsoft , hopes to set itself apart in the emoji-crazed social media game. The fact that it launched on April Fools' Day has some people skeptical about the whole thing, but it seems like it is the real deal.
Automata tells the story of androids 2B, 9S and A2 and their battle to reclaim the machine-driven dystopia overrun by powerful machines. If you have yet to give the game a try, you can still download a demo of the PS4 version through the PlayStation Store.
This celebration will culminate June 23-24, 2017 in San Francisco , CA with an ACM conference on the future of computing featuring 20 Turing laureates and other distinguished members of the computing field. "I never imagined that it would kind of have everything on it", Berners-Lee says. Today, 26 years after the launch of the first public Web page, the World Wide Web is perhaps the world's most important information medium, used by billions every day.
Now, a bi-partisan group of lawmakers is proposing the unthinkable. But refusing to tell Customs and Border Protection your password might lead agents to detain you indefinitely, confiscate your devices or send you off to be deported. But a so-called "border search exception" allowed federal authorities to conduct searches within 160km of a United States border without a warrant.
But happy Equal Pay Day , amiright? Decades later, the very first bill President Obama signed was the Lilly Ledbetter Fair Pay Act , to make it easier for women to challenge unequal pay. Trump's order undoes paycheck transparency and a ban on forced arbitration clauses for sexual harassment, sexual assault or discrimination claims - which helped women workers remain safe on the job.
The loss cut their lead at the top of the table to seven points after second-placed Tottenham Hotspur defeated Burnley 2-0. Following a awful 2015-16 campaign, Hazard has been back to his best under Conte, with 11 goals and five assists in the Premier League so far this season, and Chelsea remain favourites to be crowned champions once again come May.
A joint investigation by the United Nations and the worldwide chemical weapons watchdog determined the Syrian government was behind at least three attacks in 2014 and 2015 involving chlorine gas and that the Islamic State group was responsible for at least one, involving mustard gas.
But what I'm more bothered about is how Samsung itself seems to have hamstrung its new flagships as a reaction. Samsung officially introduced the Samsung Galaxy S8 which is equipped, for the first time in the range, with a Super AMOLED screen nearly without borders.
Sisi complimented Trump on his " unique personality ". Since the military overthrew Egypt's first post-revolution president, the popularly-elected Mohamed Morsi, a Muslim Brotherhood member, Mr el-Sissi has cracked down on political Islamists.
Aki is a normal, upbeat, schoolboy robot. In the new show, Mega Man is actually a preteen robot boy named Aki Light who fights in high-tech Silicon Valley; who spends half his time being a powerful fighter, and the other just trying to be a regular robot boy.
Where do we sign up?! But it's hard not to look at some of the quirkier games the studio's founders were responsible for at Rare, including 2008's underrated Banjo & Kazooie: Nuts and Bolts, and not feel like punches have been pulled.
Louis Fire Chief Dennis Jenkerson told reporters during a 3 p.m. news conference. One of those killed was a box factory employee, and two of the dead worked at the linen service, the St. An email message from The Associated Press to the company wasn't returned. The company was founded in 1897, according to its website. It landed in an office area at the Faultless Healthcare Linen building, killing two people, according to the newspaper.
In the meantime, more details are emerging about 52-year-old Khalid Masood, who was fatally shot by police after he stabbed an officer outside Parlaiment. The man suspected mastermind of the attack in Westminster, London has been named as Khalid Masood . So far, the police believe he acted alone when he drove a hired auto into civilians on Westminster Bridge before running into the grounds of parliament and stabbing a police officer to death.
Yesterday we reported two trustworthy sources saying that the hardware specifications for Xbox Scorpio would be revealed this week, and now Digital Foundry has confirmed on Twitter that this is in fact true. Cowboy western action game " Red Dead Redemption 2 " is highly anticipated and comes from the studio group behind the " Grand Theft Auto " franchise, and Activision's next " Call of Duty " is suspected to revert to a World War II theme after genre rival " Battlefield 1 " dove back ...
Valve is looking for new ways to highlight good games on Steam and send low quality releases to the deepest depths of the store, a kind of cheap development that they now call "Fake games". Each game on Steam has associated trading cards, and those cards are bought and sold outside of the game itself on the Steam Marketplace. As Kotaku reports, Explorers will play through poorly selling games and flag them if they enjoy it.
However, it seems there could be an issue with the new technology that would make it very easy for others to unlock the phone without having, well , your face. You can use your iris data to quickly unlock your screen, verify your Samsung account, and sign into webpages and more . You can read up on all the new S8 features and specifications here.
So what was the big deal? However, some players also pointed out that during the E3 event of past year, the game's lead designer, Hideki Kamiya, has expressed his interest in a possible sequel - stating that he has been thinking a lot about Bayonetta 3.
This year, Samsung introduced the Galaxy S8 with a bezel-free display. Samsung's bendable smartphone, dubbed the Galaxy X, might not be commercialised until at least 2019, according to Samsung Display's principal engineer, Kim Tae-woong. Another round of reports regarding the commercialization of foldable displays and smartphones emerged earlier today from South Korean publication The Korea Herald .
Now, the largest messaging app right now, WhatsApp is also in the process of integrating UPI on its platform, for peer to peer transfer of money . The company is reportedly using Unified Payment Interface (UPI) to make the payment service possible.
Since its recent launch event, which was deemed by one analyst as the start of the "smartphone innovation super cycle", the Galaxy S8 has received a handful of positive reviews. It goes without saying that the Galaxy S8 and S8 Plus will pit against the iPhone 7 and iPhone 7 Plus, the existing Apple flagships. Both the Galaxy S8 and S8 Plus are equipped with advanced 8MP F1.7 smart autofocus front camera and 12MP F1.7 dual pixel rear camera.
Had the photo been taken from a different angle or a greater distance, would it have worked? While other phone makers may boast of an ultra-slim bezel or all-glass front panel, Samsung's presentation is arguably sleeker with its borders removed.
In a brief teaser video, released on YouTube , security camera footage shows the superhuman quartet riding an elevator in Midland Circle, the mysterious corporation at the center of that literal hole in Daredevil season 2. The footage ends at timestamp 08:18:20:17, which seems to signal that Marvel's The Defenders will release on Netflix on August 18, 2017 . Marvel's The Defenders is developed by Douglas Petrie and Marco Ramirez.
The company said Apple has been working on a "separate, independent graphics design" to control its products and reduce its reliance on others. A spokesperson for Imagination said that Apple now has around an 8.2% stake in Imagination.


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Lightweight Structures B.V.
Rotterdamseweg 402H
The Netherlands
Tel +31 15 711 26 30
Chamber of commerce nr 27280593
Rotterdamseweg 402H
The Netherlands
Tel +31 15 711 26 30
Chamber of commerce nr 27280593
|Vacuum forming of thermoplastic composites
Vacuum forming of thermoplastics is a cheap, rapid and clean technique for the production of a.o. large-scale panels and structures. Due to the large deformations the material has to undergo, the technique so far has been limited to unreinforced thermoplastics.
GMT (left) and CFRP (right) vacuum formed suitcase shells
A similar technique, however, is also suitable for the forming of continuous- (CFRPs), long- (LFTs/GMTs) and short fibre (SFRPs) reinforced thermoplastics. This will open vacuum forming as a production method for semistructural and structural parts due to the high material stiffness and strength associated with fibre reinforced thermoplastics. Furthermore, vacuum forming has some additional advantages over the traditional forming methods of composite materials:
All of the above can add to a significant cost reduction over traditional forming methods of thermoset and thermoplastic composites whilst maintaining their elevated properties.
Due to the inherent advantages of the technique, vacuum forming of thermoplastic composites is a promising new technique for the rapid and low-cost production of large-scale panels and structures for application in the automotive and other industries, as an alternative for the current, costly techniques. However, in order to make optimum use of the potential this technique offers, a more thorough knowledge of the production process and the resulting properties of the final products is needed.
Application of earlier research into the production and processing of continuous fibre reinforced thermoplastics to vacuum forming of these materials within CLS has led to a prototype process, as schematically depicted in the following figures.
Schematic of the vacuum form process: a) material under vacuum in between elastomeric diaphragms; b) heating; c) moulding under vacuum (and optional additional pressure); d) release of final product
The thermoplastic composite material is first put under vacuum in between elastomeric diaphragms (fig. a). While the vacuum is maintained, the package is heated to the forming temperature in an infrared oven or between hot plates (fig. b). The heated package is then transferred over the mould where vacuum is applied between the mould and the package and the product is formed (fig. c). If required, additional pressure can be applied on top of the package. After cooling down, the vacuum between the diaphragms is removed and the product can be taken out (fig. d). A suitcase shell produced following this technique on our prototype production line, is shown in the above pictures.
What do we want to achieve?
We propose a joint project aiming at acquiring and transferring expertise on the vacuum forming process for thermoplastic composites, application of the process to a final product and further development of the process to an industrial level. The project will focus on the following items:
The several cost-saving benefits that vacuum forming of thermoplastic composites offer (see above) will be extended by further investigating and developing the protype production process, thus making full use of the cost-effectiveness of the process.
The increased mechanical properties of thermoplastic composites, will be optimally combined with the low-cost processing and forming freedom of thermoplastic materials, by investigating the opportunities thermoplastic composites with different fibre length, fibre content and fibre-matrix combinations offer, and the geometrical detail, the surface quality and final material and product properties that can be attained.
A better control of process and resulting properties, leading to an overall higher product quality reproducibility, will be achieved by investigation of the processing windows of different composites (and if needed modelling of) the process and its relation to the final product properties.
What is our approach?
The current project is planned to cover further development and up-scaling to an industrial level of the vacuum forming process and determination of opportunities the different thermoplastic composites offer. During the project, the following topics are envisaged:
Would you be interested?
We seek partners covering the complete path from raw materials to final product:
If you would like to know how you can participate in this project, please contact us!


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"Has anyone here ever been shot at?" God, is it already 21 years since that thawing Cold War afternoon of drizzle and cloud on Salisbury Plain? Standing around with a few dozen fellow platoon commanders on a training course, I was waiting to be reminded just how to identify an enemy firing position when the instructor sparked a moment of sudden interest with his question. Yet despite many of us there having already served for two years or more, only one man raised his hand in response. His experience had involved a few bullets, a few seconds of shock and an unseen gunman in South Armagh.
That short event, though, had him marked out as remarkable among us. The army that I had joined was still training for a conventional conflict in Europe. Northern Ireland, by then a theatre where the prospect of getting shot at was anyway fading by the month, was very much a secondary priority.
So until 2001, aside from a few veterans of the anomalous 1982 Falklands War, those involved with the five-day charge through surrendering Iraqis in 1991 and a small number of special forces troops, a whole generation of British army officers, from top to bottom, remained unblooded, their true leadership abilities untested.
I don't remember much else of that lesson. A few years later, I know that I recalled thinking, shot-at-a-lot while reporting in Bosnia, that the instructor had concentrated too much on explaining the "crack" and "thump" acoustics of bullets, and never once mentioned the "zip" and "zing" that they make when they are truly close. But then probably he had never been shot at either.
However, during many assignments in Helmand province over the past couple of years I have often thought about that afternoon. It isn't merely the naivety of a past era of untried leadership that contrasts with the experience of British commanders in Afghanistan now. "War" as we knew it does not exist any more. "Getting shot at" is quite unremarkable (and anyway preferable to "being IED'd" - that is, blown up by a road-side device). And killing and dying have very new implications.
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- The Brexit cringe — Mrs T would say 'No!'


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Get Well Flowers and Gifts by Art Flower Shop
Nothing says "Get Well Soon" like a vibrant bouquet of fresh flowers! Look no further for get well gifts than Art Flower Shop. We deliver get well flowers to Rockville Centre, NY or nationwide to brighten their day! You can even send a plant or a modern bouquet, either way, they'll be sure to get well soon!
|We Accept:


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Article from the York Press website, 12 May 2012.
Sean Allerton, 47, in wheelchair challenge
THE Proclaimers will be cheering on a former RAF Regiment gunner left paralysed in motorbike accident as he aims to cover 500 miles in his wheelchair to raise funds for the six charities that helped him in the aftermath of his crash.
Sean Allerton, 47, of Sherburn-in-Elmet, will set off on Monday from RAF Church Fenton – as Scottish siblings Craig and Charlie Reid, who shot to fame with songs such as "I'm Gonna Be (500 miles)" – support him from the sideline.
Sean was involved in a motorcycle crash whilst serving at RAF Akrotiri in Cyprus in 1993. He broke his neck and lost the use of his limbs and torso.
Now, he has set himself the Push 500 Wheelchair Challenge after deciding to give something back to the charities that helped him the most whilst coming to terms with his life-changing situation.
With the help of the charities who he will be raising money for – the RAF Benevolent Fund, the Royal Air Forces Association, the RAF Charitable Trust, Flying Scholarships for Disabled People, Aerobility and the Forgotten Heroes – Sean has regained partial movement and achieved his dream to fly a plane.


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This page has information about my online stream of NOAA Weather Radio KHB-36. This is the NOAA Weather Radio station that broadcasts from near Manassas, VA, and whose coverage area includes much of the Washington DC Metropolitan area. This feed regularly receives a large amount of listeners during severe weather events.
If there is no audio on this feed, please first check the NWS Public Information Statement to make sure that the transmitter isn't offline for maintenance or other problems.
Making the feed
This feed is powered by a NooElec RTL2832U-based software-defined radio. It's connected to a high-gain VHF amateur radio antenna. The audio is routed to an open-source utility called Broadcast Using This Tool, which is encoding the audio and sending it to the server. The audio filter being used is built into the SDR decoding software, and removes a large amount of the static that would otherwise make it harder to hear.
I switched from a separate scanner to a software-defined radio because the computer can now power the radio receiver (it connects via USB), allowing me to not have to power a scanner and also cleaning up some extra cables from my desk.
Listening to the feed
The stream used to be hosted by Weather Underground. Unfortunately, they experienced too many issues with their streaming audio server, and in the face of declining listenership, decided to stop providing hosting for NOAA Weather Radio streams. I'm now hosting the stream through my own streaming server instead. The link to listen in your browser will open a new tab, while the media player link will download a playlist file that can be opened in your media player of choice. I've tested the "listen in your browser" function in Microsoft Edge, Mozilla Firefox and Google Chrome.
Listen to NOAA Weather Radio KHB36 in a new tab
Listen to NOAA Weather Radio KHB36 in a media player
Keywords: NOAA weather radio NWR NWS KHB-36 KHB36 Manassas Virginia VA Washington DC streaming stream live audio


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Someone with Fred Loya insurance totaled my truck (December 2013). They took 100% liability and I had a very fair check in my hands 2 weeks later. The Fred Loya adjuster and appraiser worked fast and their communication was excellent.
I read many complaints online about Fred Loya and was very concerned. My fears were relieved when they immediately settled the claim and cut me a check. I was happy with the appraiser and didn't have to haggle for a better price.
I wish the whole situation didn't happen but since it did Fred Loya made it more pleasant. Thanks Fred Loya!
Review about: Fred Loya Insurance Claim.
Monetary Loss: $9900.
Great Comment! Would You Like to Convert It Into Review?You will be able to edit the text before publishing.
Terms of Service
Umm...this obviously was written by a company person. You could have made it less obvious by not saying your company name half a dozen times. Normal reviewers just don't write or say things that way.
Hmmm, smells like paid shill
Hi kenny807 well you might be pleased they paid your claim as my mother was but be very carful you don't have another accident because there policy is to drop you like a hot potato they give you little warning.
If you would like to give me a call and explain your situation to me more in depth my phone number is 915.590.5692 ext. 4619. My name is Sasha, I am in the office Mon-Fri 8-5 pm MST.
We understand being involved in an accident can be a hard time. We are glad we were able to help you through it efficiently and without further complications.


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SDA Bocconi Clubs
The joy of studying in a positive environment.
Clubs are an essential part of the MBA experience at SDA Bocconi. They bring people together and encourage new ideas by fueling exchanges between students, professors, alumni and the business world around areas of common interest.
All clubs are student-led and require excellent managerment skills in order to procure funds, develop business plans, as well as manage relationships with the press and private firms.
To complement a full class and study schedule, clubs enrich the MBA with various events including regattas, sports weekends, charity evenings, conferences, seminars and wine-tastings by involving students, distinguished guests and the alumni network.
Professional Clubs:
Dedicated to the spirit and activities of business and entrepreneurship in a global context.
A think-tank for discussions and activities related to the issues of Corporate Social Responsibility and Business Ethics.
Help to provide training, new knowledge, and career development in the finance sector through ongoing relationships between businesses, alumni, and academic staff.
Increase understanding of the healthcare industry and careers through company visits, seminars and training with healthcare professionals. The club also offers networking opportunities with Alumni and managers from top healthcare companies.
Aimed at providing students with hands-on exposure and a deeper insight into luxury industry. SDA Bocconi expert Faculty and Alumni network liaise students to experienced executives and entrepreneurs within the luxury sector.
Aimed at fostering interaction and mutually beneficial exchange between the world of consultancy and SDA Bocconi MBA students.
Aimed at furthering expertise, career opportunities and networking in the field of marketing.
Social Clubs:
In the land of taste, acquire wine-tasting skills, and learn to discern vintages as well as unearthing the realities of the wine-producing industry.
To bring together Football and sports lovers in general and organize the students' participation in international sports competitions. Giving insights about the sports business.
To bring automotive enthusiasts together to share passion through business and adrenalin pumping events with leading automotive companies. The goal is to increase the SDA Bocconi brand to pave the way for individuals who want to pursue a career in this sector.
Organizes running training sessions for students from all the Master programs facilitating networking among them. Manages the participation in fundraising running competitions.
Sailing as a metaphor for leadership and teamwork, combines adventure with competition by bringing together students, faculty and alumni from top international business schools, as well as guests from industry, finance and international organizations.
Connected by their love of skiing, a group of students organizes leisure and social activities, involving students and alumni from other top international business schools, as well as guests from the corporate world.


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In 2014, a major art installation of 888,246 ceramic poppies in the moat of The Tower of London marked one hundred years since the first full day of Britain's involvement in the First World War. Each poppy represented a British military fatality during the war. Remember them with this beautiful…
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Impact Lives | Donate or Volunteer
Hackley Community Care (HCC) is a non-profit 501c3 Federal Health Center with a mission to support the physical, mental and spiritual health of each person we come in contact with.
Our partnership with Komen helps us provide many women with critical screenings that detect and/or reduce their cancer risk. HCC is also a partner with the 1 in 21 community health initiative to get Muskegon County healthy by the year 2021. Our CEO Linda Juarez is co-chair of this initiative.
We believe when we address the whole person, we help foster a healthy community. That is why we offer programs such as Grandparents Raising Grandchildren; Integrated health Clinic (IHC) with a partnership with Community Mental Health (Health West is their new name); Children and adolescent health through our Teen Health Center at Muskegon High School; our School Network Hub that includes Muskegon Heights Academy, Marquette School, Covenant Academy, and Nelson School; wellness programs at Steele Middle School; Smoking Cessation; Chronic Disease Self-Management Programs and much more. We will be opening a new Teen Health Center in the Oakridge School district in the spring of 2015.
Whether an individual or family is receiving care within one of our facilities, a recipient of support services through any of our community collaboration efforts, or attending a HCC event, our extensive range of services and programs help impact many lives on a regular basis. As you can see, healthy families and a healthy community is our priority.


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You're not in a great mood today, but you can tell that there's a good reason for it. Just let things happen until the situation becomes clearer: it may take another day or so. Patience is welcome!
It's free!
Create an account and get full services: do tarot card readings, take personality type test,
like other users, find friends or love, play mind game, try it!


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The most demanded phone in the world is Perhaps Samsung Phone. One out of five people used Samsung phone. As per time and demand, Samsung Phone comes in the market so that it has become the first choice for many people.
Samsung is a South Korean multinational conglomerate company headquartered in Samsung Town, Seoul. Unlike Apple, Samsung offers lots of features according to budget category. So it is possible to be in the hand of every general to high class people. There are also many descent features in Samsung which makes it more popularity among mobile users.
Brand Conscious Consumer
On today's date people has become very conscious on brand and its product. Once they become familiar with one brand then later there is also high chance of using the same brand among people due to user compatibility. Same case has happened for Samsung Mobile.
Wide range of Selection
In Samsung mobile, based on your budget and requirement you can select the mobile. From low class to high class all types of mobile are available in the markets, you can choose of your choice with your desired features.
Brilliant AMOLED display and big Screen
It has good display and big screen so pictures can be easily watched and moved as per your wish.
Excellent service after sales
Samsung provides warranty for your device. Even if you have finished the duration of warranty, there are lots of genuine service center around you who can easily fix your device. So, you need not have to worry if any issues come in your Samsung mobile.
One important thing is that you don't need to wander around the city just for looking Samsung mobile in each and every market retail shop you can easily get it and solve the issues of your phone. So, most people used it because of its more flexibility.


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Community Health Agents Uige
Community Health Agents Uige is a project aimed at promoting community control of malaria, HIV and TB in Maquela do Zombe, Uige. The project aims to reach 30.000 people directly, through household visits and community activities by 50 Community Health Agents lessons and outreach activities at 20 schools.
The project was officially launched on the 14th of July 2016, at a ceremony attended by approximately 150 people, including the Provincial Health Director Luisa Cambuta and the Municipal Administrator for Maquela do Zombo, Banjo Henrique Moko.
After an introductory meeting with the the Provincial Director of Education about the project concept and the malaria school program, the project mapped the 20 schools to be included and held the first introductory meeting for headmasters on the 3rd of September. All involved have been very enthusiastic about the project. At the end of September, the first 49 teachers from different schools in Maquela municipality were trained on malaria, HIV/AIDS, tuberculosis and basic facts about nutrition. Training lasted four days and was led by two facilitators from the Department of Health along with project staff. The Municipal Education Director for Maquela do Zombo opened the session, and the teachers participated actively throughout the training. In addition to learning about the topics mentioned above, the teachers made plans regarding the malaria school program and about conducting lessons. On the final day of the course, all participating teachers received certificates of attendance, T-shirts for the purpose of identification and malaria manuals. The Education Director, Health Director and the Projector Leader took part. The Education Director expressed gratitude for the school program, emphasizing the importance of combining health and education by way of the malaria school program. In his speech, he said teachers and pupils had great influence in the community, and should therefore be well informed about disease prevention and engaged in health actions. He said that the teachers should use the knowledge gained and disseminate the information to their pupils and the broader community. The Director rounded off by commenting that he would follow up to see if the teachers were using the acquired information and that they were working to be at the forefront to establish the malaria control program in schools.
Simultaneously, the project recruited and trained 50 Community Health Agents and 2 Community School Health Agent Leaders. Training was conducted by staff and the Municipal Health Department. The Municipal Health Director officially opened, and participated in, the initial training, where he urged the Community Health Agents to make use of the occasion to absorb all information and acquire relevant skills regarding community mobilization. The focus was on malaria and HIV/TB, the giving of information, the imparting of skills, and a practical element carried out in the nearby community. Training ran from 19 to 29 July, with eight days dedicated to theoretical aspects and two days assigned to practical actions in the community. The closing act was hosted by the Municipal Administrator Benji Henrique Moko, the Municipal Health Director, and the Municipal Education Director, together with other facilitators from the Heath Department. In his concluding remarks, the Administrator urged the Community Health Agents to use the information acquired to educate people and strengthen links between the community and the health service. By September, 3,220 families were registered in Maquela while 15,362 people were met and talked to for the first time.
The project informed and trained 26 traditional leaders as community activists. During training, project staff explained basics facts about malaria, HIV and TB, about project expectations of the traditional leaders and of their role in the community projects in their areas. The traditional leaders were grateful for their involvement in the project in its initial phase and they are ready to work together with Community Health Agents. Traditional leaders have been participating in weekly meetings together with Community Heath Agents in two communities in Maquela do Zombo.


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- Essential Oils & Extracts
- Quality & Chemistry
Also known as 'Dalmatian' and 'Garden' Sage, this is the common herbaceous aromatic plant found in semi-arid regions the world. A member of the illustrious mint family, Sage typically reaches one meter in height with distinctly oval, fuzzy leaves and produces a large number of blueish-violet blossoms. A native species to the Mediterranean, it is now predominantly cultivated in Albania, Turkey, Greece and Italy.
This pale yellow essential oil is steam distilled from the leaves and twigs of Sage plants naturally grown in Greece


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Stone Coasters 4 Pack. These are natural stoneware Country Cats Assorted Designs Stone Coasters 4 Pack that feature 4 assorted cats on each one. The porous surface absorbs drips before they reach the bottom of the glass or your furniture. They measure 4", have cork backs, and wipe clean with damp cloth.


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Ben E King, famed and renowned singer of "Stand By Me," passed away this morning at the age of 76. "Stand By Me" hit the US Top 5 in 1961 and returned to the charts in the 1980s. The record is timeless and is used around the world to inspire collaboration and solidarity.
Emmanuel Weyi started his Stand by Me humanitarian campaign largely because of King's song. The title was certainly inspiration for our own name and we aim to continue Ben E King's message and work. http://www.bbc.com/news/entertainment-arts-32547474


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The first official photoshoot of 2017 is "in the books"! A beach proposal in Bermuda! Josh Young contacted me this past October and asked me to photograph him popping the question to his girlfriend, Emily Padgett! The couple, both Broadway Actors and Singers from New York City, already had a trip planned to Bermuda and Josh noted he wanted to propose on the beach. After careful consideration, Josh and I chose Jobson's Cove as the spot!
Josh wanted to ensure that the proposal was a complete surprise for Emily and developed a detailed plan. Emily was under the impression that she was going to model for me to help me "build my portfolio," which is a common thing asked of actors. After a few photos had been taken "for my portfolio", I directed Josh to join in. Her reaction was priceless; squeals of joy, little jumps up and down, and she said yes! I think it's fair to say that Josh pulled off the surprise! Please join me in wishing the two of them the very best as they start the next chapter of their lives together!


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BARCELONA — ExoClick today announced further integration of Paxum Payments that will now make the service available to advertisers.
The company said the Paxum global e-wallet allows users to easily send and receive money instantly all over the world with just an email address.
A long-standing client of Paxum, ExoClick said it has been providing Paxum Payments to their publishers since January 2012.
"As a result of continued good service and Paxum's ease of use, we wanted to also offer Paxum Payments to our global network of advertisers allowing them to be able to pay for our high quality traffic using an e-wallet," said Benjamin Fonzé, ExoClick founder and CEO.
Also commenting on the development was Paxum's business development manager, Ruth Blair.
"We are excited that ExoClick's advertisers will now be able to enjoy the safety and convenience of using Paxum's instant P2P payments. ExoClick is a great company to work with, and we look forward to continuing to serve their advertisers and publishers payment needs," Blair said.
For more information about Paxum, or to register a free account, visit Paxum.com.
Email sent. If you wish to send to another person, click here.


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A ban on Playstation 3 imports into Europe has been lifted by a court in the latest episode of a long-running dispute between Sony and LG.
The Korean electronics company had alleged that Sony had infringed use of its Blu-Ray technology in the games console, leading to a 10-day import ban earlier this month.
More than 300,000 PS3s were impounded in warehouses in the Netherlands while LG demanded a royalty payment of $2.50 for every PS3 sold.
The companies are currently locked in battle over seven other patents, which has led to Sony seeking to block shipments of LG smartphones to the United States.
The latest ruling by the court has ordered LG to pay legal fees of about €130,000, although Sony will still have to defend the claims of patent infringement at a later date.


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To inspire those who are feminine and crossdress. Share your pictures/suggestion/comments at firstname.lastname@example.com Disclaimer: the information on this website is published in good faith and for general information purpose only.This site does not make any warranties about the completeness, reliability and accuracy of this information. Any action you take upon the information you find on this website is strictly at your own risk.
Sunday, June 06, 2010
Come Lay Down
What a sultry photo of the beautiful t-girl as she lounges on her bed. Corsets and black lace thigh high stockings always look great and this is no exceptiong on this pretty miss. Would anyone like to join her for some nighttime fun?
Posted by Mistress Kika at 6:00 AM
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