text:
Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01730092
Recruitment Status : Recruiting
First Posted : November 21, 2012
Last Update Posted : June 11, 2019
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
- High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. Some people have disease-associated PAH and some have PAH from an unknown cause. Researchers want to follow the natural history of all PAH patients to understand how PAH progresses in order to discover targets for future research into new treatments. To further identify treatment targets, they will compare healthy volunteers to patients with PAH.
- To study the natural history of PAH.
- Individuals at least 18 years of age who have PAH.
- Healthy volunteers at least 18 years of age.
- Participants with PAH will have periodic visits to the National Institutes of Health Clinical Center. After the first visit, they will return in 6 months and then yearly or every other year for as long as the study continues.
- The first visit will take up to 3 days. It will involve the following tests:
- Physical exam and medical history
- Blood and urine samples
- Heart and lung function tests and imaging studies
- Six-minute walk test
- Questions about exercise and physical activity
- Healthy volunteers will have only one visit to the Clinical Center, during which they will undergo screening tests, and complete many of the same tests as patients with PAH
|Condition or disease
|Pulmonary Disease Pulmonary Hypertension
Pulmonary arterial hypertension (PAH) is a rare disorder associated with poor survival. Endothelial dysfunction resulting from 1) genetic susceptibility, and 2) a triggering stimulus that initiates pulmonary vascular injury, the two-hit hypothesis, appears to play a central role both in the pathogenesis and progression of PAH. Inflammation appears to drive this dysfunctional endothelial phenotype, propagating cycles of injury and repair in genetically susceptible patients with idiopathic PAH (IPAH) and patients with disease-associated PAH. However, despite mounting evidence of vascular inflammation in patients with PAH, detailed phenotypic studies are lacking on the temporal evolution of this process and its contribution to right ventricular (RV) and pulmonary vascular remodeling. We hypothesize that a detailed characterization of the temporal evolution of vascular inflammation in PAH and its impact on RV and pulmonary vascular function will add prognostic value to traditional measures of disease severity and suggest novel therapeutic targets for future research.
Patients with IPAH and disease-associated PAH will be recruited to the NIH and enrolled in this natural history study investigating the ability of circulating markers of vascular inflammation as well as high-resolution cardiac magnetic resonance imaging (MRI) to accurately stage severity of disease and/or predict clinically relevant outcomes.
The total population for the study will be 150 PAH subjects and approximately 55 age and gender matched controls (i.e. each healthy volunteer is matched to less than or equal to 3 PAH subjects).
PAH subjects will undergo 1) standard clinical examinations including 6-minute walk distance and echocardiography; 2) cardiopulmonary exercise testing; 3) markers of coagulation and fibrotic disease; 4) plasma profiling of inflammatory
markers; 5) gene expression profiling of peripheral blood mononuclear cells PBMCs); 6) high-resolution MRI-based determination of pulmonary vascularand RV structure and function and 7) Cardiac CT scan.
Plasma markers of endothelial inflammation, PBMC expression profiles, and high-resolution cardiac MRI will also be studied in age and gender matched controls to define normal ranges and variability for each of these novel assessments. Comparison of these results to PAH subjects at baseline will be used to determine the degree to which these investigative tests distinguish PAH patients from healthy subjects. Likewise, baseline clinical evaluations of PAH subjects will be used to examine whether any novel test (inflammatory markers, or cardiac MRI), accurately classifies patients according to their disease severity. In addition, these tests will be investigated prospectively for their ability to predict PAH disease progression. Disease progression will be defined prospectively as a decrease in the 6-minute walk distance of greater than or equal to10% from baseline or clinical worsening requiring an escalation in therapy, hospitalization due to right heart failure, transplantation or death.
Additional plasma will be collected from PAH subjects and age/gender matched control subjects. This material will be used to probe for new biomarkers and inflammatory factors using discovery based approaches (i.e. Proteomics and pulmonary artery endothelial cell bioassay).
|Study Type :
|Estimated Enrollment :
|270 participants
|Observational Model:
|Time Perspective:
|Official Title:
|A Natural History Study of Novel Biomarkers in Pulmonary Arterial Hypertension
|Study Start Date :
|November 17, 2012
|Estimated Primary Completion Date :
|August 31, 2022
|Estimated Study Completion Date :
|August 31, 2022
Primary clinical for PAH
Community Sample for Controls
- Examine whether any novel test (inflammatory markers or high resolution cardiac MRI), accurately classifies PAH subjects according to disease severity as assessed by their baseline 6-minute walk distance. [ Time Frame: 10 years ]Compare outcomes in PAH subjects with controls
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years to 99 Years (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Probability Sample
Inclusion Criteria for PAH Subjects:
The following parameters on RHC are required to meet the hemodynamic definition of PAH (NYHA/WHO Group I PH):
- mean pulmonary artery pressure of greater than 25 mmHg at rest,
- pulmonary capillary wedge pressure of less than or equal to 15 mmHg (or a left ventricular end-diastolic pressure of less than or equal to 12mmHg) and
- pulmonary vascular resistance of greater than 3 Wood units (240 dyn s cm(5)).
For patients with suspected PAH (Group I PH) who have not undergone a RHC and/or additional testing to confirm the diagnosis, this testing will be completed as clinically indicated under a procedural consent. If clinically indicated (diagnostic) testing indicates that the subject with suspected PAH does not in fact meet standard criteria for PAH (Group I PH), then the subject will be removed from the study.
Exclusion Criteria for PAH Subjects:
- Pregnant or breastfeeding women (all women of childbearing potential will be required to have a screening urine or blood pregnancy test)
- Age less than 18 years
- Inability to provide informed written consent for participation in the study
Inclusion Criteria for Control Subjects
Any healthy man or woman who is the appropriate age and gender for matching to a PAH patient
- Must be eligible for MRI and Gadolinium Based MRI studies
- Must be eligible for CT and Iodine Based Contrast CT studies
Exclusion Criteria for Healthy Control Subjects
- Current pregnancy or breastfeeding (All women of childbearing potential will be required to have a screening urine or blood pregnancy test)
- Electrocardiographic evidence of clinically relevant heart disease
- Symptoms of coronary or cardiac insufficiency
- More than one major risk factor for coronary artery disease (excluding age and gender)
- Obesity (defined as a body mass index > 30 kg/m(2))
- History of underlying conditions/risk factors associated with pulmonary hypertension such as collagen vascular disease, HIV infection, use of appetite suppressants, chronic liver disease or cirrhosis of the liver, chronic thromboembolic disease, congenital heart defects, hypoxemia and/or significant pulmonary parenchymal disease
- Systemic hypertension that is not well controlled (i.e. blood pressure at the time of screening greater than or equal to140/90 mmHg) in adults < 60 years old or greater than or equal to 150/90 mmHg in adults 60 years or older) on medications. Subjects taking > 2 anti-hypertensive medications will be excluded irrespective of their current blood pressure at time of screening
- Anemia, thrombocytopenia or coagulopathy
- Renal insufficiency (defined as an estimated glomerular filtration rate of < 60 mL/min/1.73m(2) of body surface area)
- Active tobacco use (> 6 months) in the past ten years, any tobacco use within 3 months prior to the screening evaluation or any tobacco use prior to completion of the study
- Inability to provide informed written consent for participation in the study
- History of recreational drug use with the exception of marijuana (as long as marijuana use was > 3 months from the time of study screening).
Exclusion Criteria for MRI in Healthy Control Subjects and Subjects with PAH
These contraindications include but are not limited to the following devices or conditions:
- Implanted cardiac pacemaker or defibrillator
- Cochlear Implants
- Ocular foreign body (e.g. metal shavings)
- Embedded shrapnel fragments
- Central nervous system aneurysm clips
- Implanted neural stimulator
- Any implanted device that is incompatible with MRI
- Unsatisfactory performance status as judged by the referring physician such that the subject could not tolerate an MRI scan. Examples of medical conditions that would not be accepted would include unstable angina and severe dyspnea at rest
- Subjects requiring monitored sedation for MRI studies
- Subjects with a condition precluding entry into the scanner (e.g. morbid obesity, claustrophobia, etc.)
- Subjects with severe back-pain or motion disorders who will be unable to tolerate supine positioning within the MRI scanner and hold still for the duration of the examination.
Exclusion Criteria for Gadolinium Based MRI Studies Only:
- History of severe allergic reaction to gadolinium contrast agents despite pre- medication with diphenhydramine and prednisone
- Chronic kidney disease (an estimated glomerular filtration rate of < 60 mL/min/1.73m(2) of body surface area)
Exclusion Criteria for Cardiac Computed Tomography in Healthy Control Subjects and Subjects with PAH:
1) Subjects with a condition precluding entry into the scanner (e.g. morbid
obesity, claustrophobia, etc.)
Exclusion Criteria for Iodine Based Contrast CTA Studies Only:
- Serum creatinine > 1.4 mg/dL
- History of multiple myeloma
- Use of metformin-containing products less than 24 hours prior to contrast administration
- History of significant allergic reaction to CTA contrast agents despite premedication with diphenhydramine and prednisone
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01730092
|Contact: Grace M Graninger, R.N.
|(301) 496-9320
|Contact: Michael A Solomon, M.D.
|(301) 496-9320
|United States, Maryland
|National Institutes of Health Clinical Center, 9000 Rockville Pike
|Bethesda, Maryland, United States, 20892
|Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 email@example.com
|Principal Investigator:
|Michael A Solomon, M.D.
|National Institutes of Health Clinical Center (CC)
Additional Information:
|Responsible Party:
|National Institutes of Health Clinical Center (CC)
|ClinicalTrials.gov Identifier:
|NCT01730092 History of Changes
|Other Study ID Numbers:
|First Posted:
|November 21, 2012 Key Record Dates
|Last Update Posted:
|June 11, 2019
|Last Verified:
|June 6, 2019
|Studies a U.S. FDA-regulated Drug Product:
|Studies a U.S. FDA-regulated Device Product:
Vascular Inflammation
Right Ventricular Function
Endothelial Dysfunction
Magnetic Resonance Imaging
Hypertension, Pulmonary
Vascular Diseases
Cardiovascular Diseases
Lung Diseases
Respiratory Tract Diseases


text:
A child no longer appears in your Xbox family on Xbox One
Your child's account no longer appears in your family on Xbox One.
Solution 1: If your child is over the age of majority, ask whether your child removed his or her profile from the family.
Anyone over the age of majority (for example, 18 in the United States) has all the rights and privileges of an adult on the Xbox One console. This means that the person is no longer subject to parental controls and can leave the family at any time.
Note The age of majority varies by country.
Solution 2: Check with other adult family members to see if one of them removed the child's account from the family.
To restore the child's account to the family, you simply need to add the person back to the family when you're signed in to your account.
Note The main reason to set up a family on Xbox One is for child account management. All adults in a family have the authority to manage the child accounts in that family, including removing a child's account from the family.
You might choose to remove any adult from the family whom you don't want to be able to change your child's account. Removing an adult from the family doesn't affect the person's Xbox Live Gold or Xbox Game Pass Ultimate subscription or content. It just removes that person's administrative rights over any children in the family.
Solution 3: Contact Xbox Support if you can't re-add your child's account, or if you think your account might have been compromised. Xbox Support can investigate on your behalf.
To provide better support, did this solution solve your problem?
Thank you for your feedback
Thanks for your feedback!
Provide feedback for this topic
Contact Us
Would you like to contact Support regarding the "A child no longer appears in your Xbox family on Xbox One" issue you were reading about or a different issue?

subset: commoncrawl


text:
Cast of "Airplane!" Return To The Cockpit
One of the all-time greatest comedy films was 1980's Airplane! This hilarious spoof of the many "disaster" films released during the 1970's became a classic, and paved the way for the Naked Gun series of films, created by the same group of creative zanies, Jim Abrahams and brothers Jerry and David Zucker. Now, a new series of commercials promoting Wisconsin tourism reunites some of the original cast members of Airplane! in the cockpit for some laughs!
"Shirley" you'll get a kick out of this! Check out the commercial here:


text:
130 Best Used Cars for 2019: Ranked by Price and Type
Fri, May 31, 2019Rankings
What is the best car to buy in 2019? It might not be the latest model! Take a look at our best used car picks, based on sales at CarMax stores.
Read More
This price does not include tax, title, and tags. Additional fees may also apply depending on the state of purchase.


text:
spike1 needed a new logo design and created a contest on 99designs.
A winner was selected from 56 designs submitted by 9 freelance designers.
We want an Identity for our childrens science show that combines a logo and caricatures of our two characters, Rustie the Robot and The JollyWizard.
Jollybops Science Show
Desired Color Scheme:
Purple,Silver,Black,White.Some Yellow but not at forefront
Desired Style:
Eye catching hip modern logo suitable for 4-8year ols
Accepted File Formats:
We will need file formats in psd,ai,jpeg,eps
Please have a look at http://www.thejollybops.com.au to get an idea of what we do. You could look at other kids websites such as The Wiggles,Hooley Dooleys,Doodlebops etc to get an idea of what could be suitable. Eventually this logo would be used on our new proposed website. Please make sure that a science lab piece of equipment appears somewhere.NB-We feel that something that combines the logo and the photo on our 'Contact Page' at http://www.thejollybops.com.au/contact.html would be ideal but we are open to suggestions. We just think that that photo encapsulates what we are about. Good luck.
Find out how a design contest works or learn more about our logo design services.


text:
Mitchell Lucker, frontman for the death-metal band rising star Suicide Silence, died Thursday of injuries in a Southern California motorcycle crash. He was 28.
Lucker lost control of his black 2013 Harley-Davidson in Huntington Beach at 8:55 p.m. on Halloween night and slammed into a Main Street light pole, police said in a news release. He died Thursday at University of California, Irvine, Medical Center.
Lucker, who lived in Huntington Beach, was ejected while the motorcycle continued south and crashed into a Nissan Titan pickup truck, police said in a news release. Two people in the pickup and nearby trick-or treaters weren't hurt.
The accident was being investigated to determine whether alcohol was a factor, police said.
Fans gathered Thursday night for a candlelight vigil at the crash site.
Riverside-based Suicide Silence members include guitarists Chris Garza and Mark Heylmun, bass player Dan Kenny and drummer Alex Lopez.
"There's no easy way to say this," the band said in a Thursday posting on its Facebook page. "Mitch passed away earlier this morning from injuries sustained during a motorcycle accident. This is completely devastating to all of us and we offer our deepest condolences to his family. He will be forever in our hearts."
Suicide Silence has released three Century Media albums: "The Cleansing," ''No Time to Bleed" and "The Black Crown."
Century Media's website describes Suicide Silence as the "modern death metal band for a new generation."
Lucker said on the record company website that the band is carving out an abrasive niche of its own.
"No imitators, no second guessing. I want it to be known," Lucker said. "It's the same thing as when you pop in a Korn, Deftones, or Slipknot CD: you know that stamp is there."


text:
Guide to iPad Education Deployment in Schools
After deciding to use iPads in the classroom, start by developing a strategy for the iPad deployment. Base your deployment strategy on the number of iPads you want to introduce. Are you setting up a few iPads for teachers to try out, maybe anywhere from 20 up to 150 or so for a few classes to use — or a few hundred for an entire organization?
Deployments fit neatly into the following three categories.
For personal iPad deployment in schools, use iTunes
This personal deployment is thankfully the easiest and closest to the model being used by millions of iPad users around the world. Just set them up one by one with an Apple ID and an iTunes account. You can either share a school account or allow some users to manage their own.
Buy the apps, or tap the Purchased option in iTunes and download apps that have already been bought and made available to each device.
Synchronization and app upgrades are relatively easy. You can attach the device to a computer with iTunes and elect to have updates done wirelessly. Use iCloud, and documents and data can also be synchronized among your various devices.
It's painless, quick, and gets you rolling quickly . . . even leaving you with a smile on your face!
For large iPad deployment in schools, use MDM solutions
Large-scale deployments are for entire organizations, schools, and school districts. The numbers can range from 150 iPads up to many thousands. To clarify what may be obvious, if you aren't an IT professional, run screaming . . . now.
You stayed, so you must want to know more. For large-scale deployments, you need a system that enables centralized control over the management of large numbers of devices. Those solutions fall under the category of what is generally called Mobile Device Management, or MDM solutions.
MDM software gives IT departments the capability to enroll devices in a centrally managed environment, wirelessly configure and update their settings, and even remotely wipe or lock managed devices. Several third-party MDM solutions are available for managing iOS devices. They communicate using the Apple Push Notification service to wake up enrolled devices and check in with the MDM server to retrieve pending actions or queries.
If you Google MDM management of iOS devices, you'll get a comprehensive list of options that you can evaluate. Just make sure you give it to the right IT professional.
For small to midsize iPad deployment in schools, use Apple Configurator
The small to midsize deployment is characterized by anywhere from 10 to 150 iPads, and it could be for a small school, a pilot program, or individual classes.
Apple has made important strides in enabling the management of smaller deployments without the need for dedicated IT involvement. It does still require a fair amount of reading and training, but it's definitely possible to manage your small deployment of a class set of iPads.
Your best option is using a free tool from Apple called Apple Configurator. Use Configurator to set up new devices, install apps, and manage individual settings. It's a perfect solution for classrooms or smaller deployments, especially because settings, apps, and policies change so rapidly.
You can use Apple Configurator to assign devices to specific users and personalize them with data and documents.
Apple Configurator works on your laptop or desktop and can be downloaded from the Mac App Store. It uses three simple workflows to prepare new iOS devices for distribution, supervise device configurations, and assign those devices to users.


text:
Toggle navigation
Night Pizza Drive
Order UpMenu demonstration
Please be advised that the following entity is the administrator and controller of your personal data: Tastysoft Sp. z o.o., located in Łódź at ul. Sienkiewicza 85/87 (floor XI, room 8), 90-057 Łódź, National Court Register No.: 0000411725, e-mail address: email@example.com: a) Your details shall be processed in response to your request and addressed to the Administrator. You need not provide them, but if you fail to do so, it shall make contacting you impossible. b) Your details shall be made available to persons (employees) authorised by the Administrator only for the purpose of fulfilling your request for contact. c) Your details shall be stored until communication, initiated by filling-in this form, is completed. d) You shall have the right to access your personal details, rectify, delete, limit their processing and/or transfer them to another administrator. e) You shall have the right to lodge a complaint with the Supervisory Authority which controls the legality and accuracy of the processing of personal data. f) Your details shall not be transferred outside the EU or to any international organisation. g) Your details shall not be subject to profiling or automated decision making.
Hello. My name is Marta.
Join me to see the demo.
I will show you how to use UpMenu and online sales to increase the profits of your restaurant.
Subscribe to the newsletter
I have read the
privacy policy
Subscribe to marketing updates. By ticking this checkbox you are subscribing to receiving marketing information from UpMenu.com. The marketing information maybe sent to in the form of emails or text mesages or both as long as you have provided the correct contact information. You have the right to withdraw your consent at any time. For more details you are kindly invited to review our
Privacy Policy
I agree to receive commercial information at the email address provided (optional)
I agree to receive commercial information on the given telephone number
The best weekly tips on marketing and restaurant management
We have more than 10,000 subscribers. Become one of them.
No spam, no ads!
Please be advised that in order to provide services available on our website, to optimize its content and to adapt the website to your individual needs, we use information saved using cookies on end users' devices. Cookies can be controlled using the settings of your web browser. Your continued use of our website without changing your browser settings means that you accept the use of cookies. More information is included in the website's
privacy policy


text:
Take a dip into the fountain of youth at Le MedSpa, your source for quality skin and beauty care in Grand Junction, Colorado. We are committed to providing you with the highest quality care in a pleasant, professional atmosphere. Healthy Skin Starts Today At Le MedSpa.
Whether we're addressing your skin needs or relaxing you with our luxurious spa treatments, our top priority is to ensure that your experience with us is second to none. We believe in the importance of patient education and promise to keep you thoroughly informed of your treatment options and progress.
Dr. Richard E. Stiefler, MD, FAAD Le MedSpa Medical Director is Board Certified in Dermatology and Dermatopathology. He is well educated in medical and cosmetic dermatology. We are the only MedSpa in Grand Junction with a skin specialist as the medical director. We offer a full-range of skin care services specially designed around your individual needs.
We know the benefits in health and self-confidence that looking and feeling your best can bring. This is why we offer a broad-range of procedures to reverse the signs of aging, reduce stubborn fat, sculpt your body, and help you achieve radiant skin. Celebrate the skin you're in!


text:
(Fairfield, CT) - Brittney Lane (Greenwich, NY) and Jeremy Rosado (Brooklyn, NY) were both honored as Northeast Conference Women's and Men's Track Athletes of the Week and Gregory Hazell (Airmont, NY) was named NEC Men's Rookie of the Week for their performances in the CTC Indoor Relays at Yale University this past weekend.
Lane won the 5000-Meter to lead the SHU Women to a 15th consecutive team title at the CTC Relay Carnival with a time of 17:31.67. In doing so, she also took an early NEC leading time set a personal best by 20 seconds, and most importantly, qualified for the ECAC Championships in March.
Rosado produced the fastest 60-meter hurdles time in the league on opening weekend with a first place time of 8.22s. With his victory, Rosado qualified for the IC4A Championship in March as well.
Hazell triple jumped his way past a field of 14 competitors while accounting for the NEC's top mark thus far in his collegiate debut. He qualified for the New England Championships with a bound of 14.04m (46' 0.75").


text:
Please keep an abstract of your idea (max. 200 characters), statement of motivation (max. 400 characters) and CV ready for the application process. Please note that some of the information will be used for event material.
The application must be filled out in English.
If you have any questions, please do not hesitate to send us an e-mail to firstname.lastname@example.com or visit our FAQ section.


text:
Stock markets continued to hold their gains for 2013. For the year-to-date, the S&P 500 ( SPX) is up 6.81%, while the technology sector is under-performing. As measured by the PowerShares QQQ ( QQQ), the ETF is up 4.02% so far. The rising bullishness brings higher risks for a sell-off, but bears are taking profits on their bets for a number of tech stocks: (More Tech Lists: Watch These 9 Blackberry Suppliers) Data Source: Bloomberg Notable Companies to Watch: 1. NVIDIA Corporation ( NVDA): Provides visual computing, high performance computing, and mobile computing solutions that generate interactive graphics on various devices ranging from tablets and smart phones to notebooks and workstations. Market cap at $7.95B, most recent closing price at $12.73. Short-selling volume for NVIDIA ( NVDA) declined by 24.5% between January 15 and January 31, 2013. The company reported quarterly earnings that beat estimate, but guidance was once again light. In its Q4 report, Tegra sales rose +90% compared to a year-ago. Graphics chip sales rose 7%, but NVIDIA was cautious on its mobile growth. The company will need an integrated baseband and app processor to compete more effectively against chip-giant Qualcomm ( QCOM). The company earned $0.28 per share in Q4 on revenue of $1.11B. NVIDIA expects revenue to be $940M, below estimates of $1.07B in Q1.
2. OCZ Technology Group, Inc. ( OCZ): Designs, develops, manufactures, and distributes computer components for computing devices and systems worldwide. Market cap at $140.71M, most recent closing price at $2.08. Short-sellers reduced their bearish position in OCZ (OCZ) by 9.5%. Shares plunged 10.2% after the short-volume decline. OCZ said revenue is expected to be between $65M-$85M for Q2 and Q3 ending August and November 2012, respectively.
3. CIENA Corp. ( CIEN): Provides communications networking equipment, software, and services that support the transport, switching, aggregation, and management of voice, video, and data traffic. Market cap at $1.64B, most recent closing price at $16.15. CIENA rose steadily throughout February, after open short- volume declined 7.5% to 17.28M shares. Its competitor, JDS Uniphase ( JDSU) reported very strong earnings and gave strong guidance. The optical components and testing segment remains very strong.
4. Cree, Inc. ( CREE): Develops and manufactures light emitting diode (LED) products, silicon carbide (SiC) and gallium nitride (GaN) material products, and power and radio frequency (RF) products. Market cap at $5.33B, most recent closing price at $45.72. Cree rallied significantly, and is up nearly 50% for the quarter. A short-squeeze scared off some bearish investors, as open short-selling declined 5.5% to 15.1M shares. Cree's Q2 results were strong, and guidance for next quarter is even better. The company's vertical integration from retail to supply is on-track to allay worries of weakness ahead. Cree named Mike McDevitt as interim CFO as its new permanent CFO.
( List compiled by Kapitall Contributor Chris Lau)


text:
Broadband does interfere
In a recent letter, Tony Whelan, CEO of an Internet service provider, makes the claim that his "very live roll-out" of broadband-over-powerline (BPL) Internet does not interfere [September 2: " This broadband doesn't interfere].
He cites several examples of critical radio services which have not experienced harmful interference from his BPL system. But there is more to the picture than the vignette Whelan paints.
None of his stated examples use the medium or high frequencies which are most susceptible to harmful interference from BPL. His examples are all members of the Aviation and Land Mobile radio services which use the much quieter VHF and UHF frequencies. BPL interference is 10 to 100 times as intense on the lower frequencies used by AM broadcast stations, and short wave frequencies used by military, government, airline, maritime, and amateur radio services– many of which are crucial to life and limb!
An added problem with BPL is that it not only affects the neighborhood where the wires are located, but those same wires act as giant antennas to radiate their errant signals over theÊlong distances that the MF and HF radio waves can propagate. This means that the Manassas BPL system could potentially interfere with an airliner over the Atlantic Ocean trying to make vital contact with the New York Air Traffic Control Center.
I suggest the power utilities stick to delivering 60-Hertz electrical power and allow the cable and telephone utilities to deliver the radio-frequencies they are so much better equipped to deliver in a professional, responsible manner.
Joe Shupienis
FCC Licensed Consulting Radio Engineer
Pittsburgh, PA


text:
Groups Specializing In Hearing Loss and Deafness
You'll be positively amazed at the number of groups in the United States that focus on hearing loss and deafness. Their information, advice and perspectives can be a great help to you and your child over the coming years. To get you started, we've listed many such groups in the section entitled "Find Out More" at the end of this publication.
Last Modified: 01/04/2007


text:
Story highlights
- Spartacus was a 3-year-old Belgian Malinois at the Woodstock Police Department
- The K-9 was cross-trained in drug detection, tracking and apprehension, police say
- Authorities are not identifying Spartacus' handler
- The handler has been placed on administrative leave, authorities say
A police dog died of heat stroke after being left in a patrol car in Woodstock, Georgia, authorities said Tuesday.
The 3-year-old dog, a Belgian Malinois named Spartacus, was found dead Monday night inside the K-9 handler's car, which was parked outside his home, Brittany Duncan, a Woodstock Police Department spokeswoman, said in a written statement.
A necropsy requested by the police department determined the cause of death was heat stroke, the statement said.
The statement did not detail why the car was parked at the handler's house nor did it say how long it had been parked there.
"The K9 handler is currently on administrative leave with pay pending the outcome of an internal investigation," Duncan said.
The police department did not publicly identify Spartacus' handler, describing him only as a 9-year police veteran who has worked as a K-9 handler for seven of those years.
"After the retirement of his first police K-9, who is now a family pet living with the K-9 handler, the handler is devastated by the loss of his second police K-9," Duncan said.
Spartacus was cross-trained in drug detection, tracking and apprehension, according to the department.
A memorial service for Spartacus will be announced at a later date, Duncan said.


text:
Fam. Schwarzbach
Dear family Schwarzbach, we would like to thank you for your 10th stay at the Activ Sunny Hotel Sonne. We are looking forward to welcoming you at our house again in the near future!
P.S. The entire picture gallery is available as download. Please click on the symbol on the right side below the picture.


text:
RV & Boat Storage
StorageMax has storage options for all of your outdoor recreational vehicles. Our RV storage and boat storage spaces will provide you the peace of mind in knowing that your valuables are safe and secure. Several of our StorageMax facilities provide both Covered RV/Boat Storage, and Open RV/Boat Storage in a range of sizes to accommodate most Recreational Vehicles. We also have room for your boat, trailer, motor sport vehicle or auto. Check our competitive RV/Boat Storage Rates for all sizes and prices.
The customer self parks their vehicle and has access in to StorageMax with a unique PIN code seven days a week. StorageMax facilities are lighted, surrounded by secure fencing, and monitored 24 hours per day by camera surveillance. Spaces are rented on a month-to-month basis with no long term contract to worry about.
For your added protection, we have compiled a list of RV and Boat Storage Tips.
Boat Storage Tips
The following steps can be taken to protect your boat while in storage. Additionally, specific procedures recommended by the boat manufacturer should be closely considered.
- Prepare your engine in accordance with the owner's manual. In winter, this will normally include draining and flushing the cooling system; draining and refilling the crankcase; applying oil to inside of each cylinder through the spark plug holes; and other preservative actions.
- Thoroughly clean the hull, decks, cockpit, bilge, all compartments, lockers and the exterior of engine, and coat with an appropriate wax or preservative.
- Drain fuel lines, pumps, carburetor and tanks or fill completely, and add fuel stabilizer.
- Leave all floorboards up, doors ajar, ports and skylights open, hatches partly open, drawers and lockers open.
- Carefully fit a well-made cover, provided with ventilation ports. If boat is to be stored outdoors, make sure there are no low spots in the cover that will hold rainwater.
- Place a cover over engine. Do not leave the engine exposed to the sun or rain.
- Don't forget the trailer. Check tire pressure, and cover tires, if they will be exposed to the sun. Check and pack wheel hubs, if necessary, and lubricate jack.
- Finally, note dates of registration, tags, certificates and insurance, etc., and plan for renewal, if they expire during your storage term.
RV Storage Tips
- Review your owner's manual for system storage tips.
- Make sure to remove all perishable items from cabinets and refrigerator.
- Clean the inside of refrigerator and leave door open to ventilate.
- Turn off refrigerator, verify that all power sources are off by checking 12 volt, 110 volt and LP gas.
- Clean rooftop A/C filters and cover the outside unit.
- Clean the interior of the RV, pull shades and close blinds.
- Turn off the propane cylinders and cover the regulator.
- Cover vents to the furnace and range hood for long-term storage.
- Close all roof vents and windows. If needed, used chemical-type dehumidifiers to prevent condensation.
- Check tire pressure and cover the tires if they are exposed to outdoor elements.
- Inspect roof, body, interior, soft molding and caulking.
- Service locks with spray lubricant to prevent rust and freezing.
- Remove batteries, store in an area that is not subject to outdoor elements and test periodically; charge if necessary.
- For motorhomes, check all operating fluid levels under the hood, top off the gasoline tank and add a fuel stabilizer.
- Make sure to empty and thoroughly rinse out all holding tanks. During the winter, all water tanks, lines and pumps should be drained and filled with non-toxic RV antifreeze to keep from freezing the system.


text:
Among the most common sweets that is suitable in nearly every condition will be the endless chocolate cake. It's straightforward and very popular - infact, almost everybody has, once in his/her living, endured a bit of it. Who wouldn't need a preference of delightful, beautiful chocolate? Study has said that eating chocolate is from the mind releasing content neurotransmitters, consequently improving the elated feeling we get when eating chocolate. Creating a cake nowadays isn't restricted to the abundant and inspiring anymore - together with the chocolate dessert's superior mobility, Flourless Chocolate Lava Cake, it takes only the absolute minimum period of time and components having a splash of imagination.
Chocolate happen to be around for around two-hundred and fifty years, with Dr. James Baker's development - grinding cocoa beans to make chocolate. But chocolate desserts were not produced industrial before 1930s; up to then, all chocolate recipes were for chocolate beverages only. Since that time, there is a huge variety of alternatives for different types of chocolate desserts, a number of which are Devil's food cake, Black Forest, Chocolate Souffle, Garasch, Sachertorte along with the classic layered chocolate cake. You may also decide to incorporate infused sweets and amazing styles into your mixture, for example wine, fruits, nuts, also red pepper! Pastry-creating with chocolate has turned into a rewarding experimental organization by itself.
You may think baking desserts is really a point reserved just for registered and seasoned patisseries, but together with the following easy steps, you could find yourself enjoying a vigorous chocolate dessert dessert together with your family. The components are straightforward, though ofcourse applying premium quality components is essential for better desserts, it isn't generally the best option concerning the cash you would possibly invest. The components for our easy chocolate dessert contain: 1/2 glass self-raising flour; 1/2 glass wonderful sugar; 2 Tbsp cocoa; a touch of salt; 1/4 pot melted butter; 1/2 cup milk; an egg as well as a minor splash of vanilla. These components it is simple to discover in nearly every supermarket, consequently obtaining them will not become a dilemma. Seeking realistically-valued but high quality components is really a concern to all starting bakers.
Flourless Chocolate Lava Cake was uploaded at April 12, 2015. Hundreds of our reader has already save this stock photographs to their computer.
This photographs Labelled as: Chocolate Cake, cakes subject, . You can also download the photographs under Flourless Chocolate Lava Cake articles for free. Help us by share this photographs to your family.
Download Image
Share this lovely cake pictures to your friends, click below:


text:
Technical Support
The Herkimer College Information Technology office provides and maintains computer hardware and software across campus for students, faculty, and staff.
The Information Technology department comprises three technical areas that provide services:
Programmers maintain the 'Banner/Student Online Services' database which provides vital academic information.
Network technicians maintain the electronic infrastructure that allows communication between campus users and computing resources.
- Computer Technicians maintain the computing hardware and software so that campus users have access to reliable equipment and technical assistance.
The entire department works together to manage and support the entire College's technology infrastructure to ensure an enriched teaching and learning environment as well as efficient and effective operations. We also strive to provide an outstanding Online Learning experience, as well as assistance with applications like Student Online Services, MyHerkimer.edu, Track-It, and Webmail for Faculty and Staff or Webmail for Students.
If you have a question, the answer might be on our Frequently Asked Questions page or in our Computer Use Policy. If it's not, don't hesitate to visit us in JH 113, call (315) 574-4021 or (315) 866-0300 x 8555, or contact the Help Desk during the Spring/Fall from 8:30am to 6:00pm Monday - Thursday, 8:00am to 4:30pm Friday. Summer Hours are 8:00am - 4:00pm. Requests are entered into our Trackit system and are resolved either by the Help Desk technicians who are dispatched to resolve issues as quickly as possible.


text:
Get real-time views on product data, vendor performance and integration with systems of record.
Give customers a place to view or purchase different product options or request on-demand assistance from a sales associate for help.
Gain real-time perspective and data-driven recommendations on product and vendor performance.
Automate the scheduling process so employees can see their own schedule from their iPhone. Easily swap shifts while keeping managers informed of the changes.
Brick-and-mortar stores can use big data analytics and iBeacon location awareness to help sales associates find items in sequence based on proximity – and consolidate items across multiple orders.


text:
Hey Audience,
So many of you have submitted awesome Twansitions to http://bit.ly/Twansitions, and I had to post this one.
Aahhhh man. Repeatedly doing my Duke Nukem impersonation has finally paid off.
I used to host all the fanpics on this site, but the bandwidth got ridiculous. BUT! I'm going to have the facebook fanpage integrated with this site very soon, so that'll be a party. An integration party. Lots of integration at that party. And GHB. Whatever that is. Acronyms are fun.
SO MUCH TO LOOK FORWARD TO! I'm doing a new show that starts in a week and a half, plus I starred in a BlackBoxTV ep yesterday (http://youtube.com/blackboxtv), where I'm actually serious. Aawwkkwaardd. I'm excited to see it!
Bless your face,
Peace off,


text:
Thank you for racing with us in Zurich. We appreciate the efforts and support of the city, volunteers, sponsors, and everyone else involved in putting on this race. We would also like to thank all of the athletes who have raced with us here.
We would love to see you continue racing IRONMAN Switzerland Thun as the race moves to Thun in the heart of Switzerland on 12 July 2020.
Join us at IRONMAN Switzerland Thun.


text:
Hollywood loves talking money — salaries, budgets, you name it. The game industry doesn't.
Some developers have been very open about how much their titles cost to produce. Other developers have not revealed their budgets. As Kotaku mentioned earlier when posting the Digital Battle.com list of games with the biggest budgets: "The sticky part of video game budgets is that some developers will not confirm the actual budgets, and there is some speculation in these numbers."
Metal Gear Solid 4 producer Ken Imaizumi has stated that the claim that the PS3 exclusive cost $60 million is incorrect.
"It's being written in recent news that MGS4's budget was over 5 billion [yen] or 7 billion [yen]," Imaizumi tweeted. "It didn't cost that that much." If it cost that much, Imaizumi added, the game would've become multi-platform.
Then how much did it cost?
Reuters indirectly quoted former Kojima Productions Associate Producer Ryan Payton as saying that the game was so expensive to develop, that it needed to sell a million copies on launch day to turn a profit. (Payton later stated that he had been misquoted, and that the information was incorrect.)
Then, that brings me back to: How much did it cost? Movie producers and directors have no problem talking about how much was spent on making a feature film and neither should game developers.
Kotaku has reached out to Kojima Productions for a comment.
(今泉) kojima_pro [Twitter]


text:
Dr. Frank Fisher, Associate Professor of Mechanical Engineering at Stevens Institute of Technology, has recently been added to the Fulbright Specialist Roster as a candidate for grants to cooperate internationally on academic development. Funded by the US Department of State, the Fulbright Specialist Program places leaders from higher education and industry in global collaborations that strengthen the positions of US institutions.
"Dr. Fisher was selected for this distinguished honor in recognition of his academic leadership as well as his forward-thinking nanotechnology research," says Dr. Constantin Chassapis, Deputy Dean of the Charles V. Schaefer, Jr. School of Engineering and Science and Department Director of Mechanical Engineering. "His promising explorations in energy harvesting and high-performance polymers are equaled by his engagement in educational and outreach programs at Stevens that instill a love of engineering in K-12 students."
On the Fulbright Roster, Dr. Fisher will be listed as an expert in the area of Engineering Education: Theory, Curriculum and/or Pedagogy. He has developed these skills at Stevens as Co-Director of the Nanotechnology Graduate Program and through programs that convey the excitement of STEM education to grade school students in New Jersey. This is the latest of Dr. Fisher's many honors, which include the National Science Foundation CAREER Award and the Outstanding New Educator Award from the American Society of Engineering Education. Recently, he was recently named one of "the Nation's Top Mechanical Engineers" by Inventor's Digest.
The Fulbright Specialist Program is conducted by the Department of State Bureau of Education and Cultural Affairs to promote international cooperation in supporting the needs of institutions of higher education. Specialists are consulted when needs arise in the areas of teacher training, short-term seminars and lecturing, special conferences, curriculum planning, and academic development. Roster candidates may travel abroad to collaborate with their international counterpoints, supported by Department of State funding, enabling a wider range of scholars to benefit from the Fulbright vision.
For more about engineering education at Stevens, visit the Mechanical Engineering Web site, or Undergraduate or Graduate Admissions.
About the Department of Mechanical Engineering
The Department of Mechanical Engineering confidently addresses the challenges facing engineering now and into the future, yet remains true to the vision of the founders of Stevens Institute in 1870 as one of the first engineering schools in the nation. The department mission is to produce graduates with a broad-based foundation in fundamental engineering principles and liberal arts together with the depth of disciplinary knowledge needed to succeed in a career in mechanical engineering or a related field, including a wide variety of advanced technological and management careers. This is accomplished through a broad-based Core Curriculum of applied sciences, engineering sciences, design, management, and the humanities, coupled with a long-standing honor system. Learn more: visit www.stevens.edu/ses/me


text:
* denotes required field
It is the night of the exciting, action-packed and awe-inspiring Freestyle match. These bouts feature multiple-competitors and only one can win. Three Way Freestyle features the three premiere high-flyers in the world today in PAC, Ricochet and Rich Swann. Four Way Freestyle has four of the best going right now with YAMATO vs. CIMA vs. Masato Yoshino vs. Johnny Gargano. However, it's the first ever Eight Way Freestyle opening match that steals the whole show! Plus, Austin Aries vs. Susumu Yokosuka, Arik Cannon vs. Masaaki Mochizuki and more!!!


text:
Color: Black
Interior: Leather
Drive Train: FWD
Transmission: Manual
Vin: 1C3CDFCH2DD306500
Engine: 1.4L L4 DOHC 16V TURBO
Mileage: 96,445
Stock #: D-6500
J.M. Uvanni Motors
5829 Rome Taberg Rd.
We attempt to update our website in a timely manner however we the dealer can not guarantee that the inventory shown will be available at the dealership. We cannot be responsible for typographical and other errors, including data transmissions or software errors that may appear on the site. If the posted price, incentive, offer or other service is incorrect due to typographical or other error we will only be responsible for honoring the correct price, incentive or offer. We make every effort to provide you the most accurate, up-to-the-minute information however when you are ready to purchase products or services, it is your responsibility to verify with us that all details listed are accurate.
Mid-model-year manufacturing changes, as well as dealer-added accessories on the actual vehicle may differ from the options and features shown. Actual pricing and vehicle information must be verified by us at the time of purchase.
Images shown may not necessarily represent the configurable options selected or available on the vehicle.
*lifetime powertrain warranty is only available on qualified vehicles, please contact dealer for lifetime powertrain warranty details and qualifications.
I hereby consent to receive text messages from or on behalf of dealer at the mobile phone number I provided above. I understand that I am opting in to receive text messages from dealer or their employees. I include consent to receive phone calls at the mobile phone number I provided. I understand that message and data rates may apply.


text:
Are You Weighing Yourself Too Much?
The Daily Devoted
I weigh myself every morning. If I go up 2 pounds, I'll opt for a salad and chicken. But if the number drops, I'll order a cheesesteak and get Dairy Queen for dessert! —Lisa DiBello, 30; Havertown, Pennsylvania
If you're dieting, it's smart to weigh yourself daily. People who did lost twice as much as those who weighed in less often, a study from the University of Minnesota, Twin Cities finds. Regular checks keep you focused, Dawn Jackson Blatner, R.D., of Chicago says. But using the number to pick the day's food won't help your frame (or psyche): Daily ups and downs are usually due to water weight, not lasting loss or gain.
"To get the real picture, write down your weight daily and average it weekly," says Irene Rubaum-Keller, a psychotherapist in Los Angeles. "Use the trend to inform your diet."
Courtesy of subject
The Diehard
I step on the scale in the morning and again at night. I'm heavier at night, so when I wake up and weigh less, I feel as if I'm on the right track. —Laura Berger, 40; Fort Lauderdale, Florida
You may weigh less in the morning, but that doesn't mean you've truly shed pounds. (Sorry!) Post-slumber dehydration is the cause of the lower a.m. read. "Taken to an extreme, frequent weigh-ins every day could lead to an unhealthy obsession or even an eating disorder," says clinical psychologist Lavinia Rodriguez, Ph.D., of Tampa Bay, Florida.
If you're hooked on hopping on, cut back to once a day and stash the scale in your closet to hide temptation. And rather than motivating yourself with phony results, focus on actual triumphs, like finishing an ass-kicking workout.
Courtesy of subject
The Scale-Phobe
I refuse to step on the scale—it gives me anxiety. Whatever the number is, I'm never satisfied. I begin obsessing about being too heavy. —Terri Huggins, 23; Sayreville, New Jersey
"It's common for women of all sizes to avoid the digital beast," Rubaum-Keller says. In fact, 21 percent of you view it as the enemy, according to a Self.com poll. "Some women tie their self-esteem to their weight. Others would rather not know because they're not ready to change their diet," Rubaum-Keller says. But avoidance sets you up for a rude awakening when you do get the guts to step on—which could lead to a blues-induced binge or a too-drastic diet. "To make peace with the scale, confront it," Rubaum-Keller says.
Start by weighing yourself once a month, then work up to weekly. If the digits make you cringe, consider this: Now that you have the facts, you can make healthy changes.
Courtesy of subject
The Weekly Weigher
I weigh myself on Friday mornings. It encourages me to continue eating healthfully and exercising on weekends. —Danielle La Casse, 28; St. Petersburg, Florida
To maintain your weight, weekly weigh-ins are your best bet. Seventy-five percent of people in the National Weight Control Registry (a study of dieters who have lost at least 30 pounds and kept it off for a year or more) weigh themselves once a week.
Friday is a good day for it because that number stays on your mind all weekend, when you're prone to chowing down, Blatner says. Getting on the scale first thing is also wise (81 percent of you do it!); exercising and eating can sway results. Don't freak if the number creeps up one week. Consistency is key, so average a month of numbers before making any overhauls.
Courtesy of subject
The Scaleless
I never weigh myself. If my pants feel tight, I'll eat less chocolate and hit the treadmill more often. —Allison Dwyer, 32; Jersey City, New Jersey
If you're happy with your shape and not concerned about the number on the scale, it's fine to use clothes to hold yourself accountable to eating right and exercising regularly, Blatner says. But make sure you're measuring with fitted jeans and not your "pigging out" yoga pants.
That said, it's helpful to weigh yourself at least once a year. Gaining a few pounds a year can add up and put you at greater risk for disease, Blatner says. And the pounds could be creeping on without your realizing it—you know, even jeans stretch.
Courtesy of subject
How often should you weigh in?
Assess your goals. What you want to accomplish should guide your habits:
- When you're trying to trim, daily checks are ideal. They offer proof that hard work pays off and remind you to keep it up.
- If you hope to maintain, weigh in weekly. This will alert you if the digits rise over time.
- Scale haters can use pants to see changes, but weigh yourself annually to keep it real.
Tweet your #scalesecret to @SELFmagazine.
The Surprising Secret to Loving Your Body
6 Ways to Fire Up Your Metabolism
Stephanie Rausser


text:
Map of Rathdowney, QLD
Not the 'Rathdowney' you were after? Try the other Rathdowney (the regional area) in Queensland.
Create a custom map: Click here to create a custom map including 'Rathdowney'
Link to this page: Click here to see how
©2019 Digital Atlas Pty Limited | Usage Terms | Data Sources
If you do not agree with the Usage Terms then do not access this website.


text:
Do Not Be Anxious | Poster A0
Do Not Be Anxious | Poster A0
Print this PDF licence as an A0 poster for a group project or display.
Add To Cart
This PDF file is A0 size (841 x 1189mm) and is licenced to be printed once as a poster. Please purchase a separate licence for every printout. Large poster files may be printed commercially at small printers or stationary shops. (Please be careful of the paper you choose as you may not be able to colour or paint papers which have a coating on them.)


text:
When I told a friend I was playing Dead Space 3 for this review, his eyes lit up at the thought of the thrill ride he imagined I must have been having.
"Ooh, scary!" he said with a grin.
Dead Space 3 continues the story of science fiction's handiest engineer, Isaac Clarke, as he struggles to contain the galaxy-wide spread of Necromorphs and contend with Unitologist soldiers with motives of their own.
The increasing influence of cover-based this and co-operative that in shooters threatens to have a negative impact on Dead Space 3, taking it out of the cramped corridors of survival horror and bringing it, after some scene-setting chapters, to an ice world where the series' lingering questions will finally be answered.
The first full chapter is reminiscent of last year's Gear of War wannabe from the Resident Evil series, Raccoon City Chronicles, which was more laughable than lethal, and takes some patience to complete. Character movements aren't as fluid as they could be, and it's a fine line between comedy and tragedy when your character is trying to stomp Necromorphs but hits only empty space, looking less like a beatdown and more like a hoedown.
Dead Space 3 could easily have gone the same way as Raccoon City Chronicles in its quest for relevance - but the thrill of shooting apart wave after wave of Necromorphs with surgical precision and stomping their bloodied remains for items adds some gloss to the experience, even if it doesn't raise it above the pack.
You can play a 25th century MacGyver thanks to the game's ingenious use of Clarke's engineering talents. Using the in-game workbenches, you can use space junk to craft your own weapons. It's here, hopping aboard the as-you-like-it bandwagon, that Dead Space 3 truly shines. There's some controversy around the microtransaction facility that lets players buy the bits they want, within reason, but purists can easily ignore it. Mobile gamers used to authorising pay-to-play transactions may enjoy it.
The characters, items and holographic user interface are beautifully rendered and float superbly over richly detailed environments that are clearly labours of love but are dead spaces themselves, reminding me of Jon Toogood's La La Land, with everything and nothing at all.
All would be lost right there if not for the sound design. The dialogue's not memorable, but the music and effects bathe the game in so much atmosphere you almost need Nasa clearance just to handle it. If you can, play this game with a good quality headset. When the Necromorphs fail to give you the willies on sight, the audio picks up the slack with incidental music creeping in to overwhelm the standard track as the reanimated corpses try to do the same to you.
Dead Space 3 is an interesting and contradictory animal, as if constructed using the finest parts taken from the biggest cats in the jungle - then thrown into a potato sack and left in the rain for a few days until it looks like a questionably soggy moggy in need of a meal and a place to curl up. Despite its flaws, it's worth a look, and may even grow on you when it's time to replay the story mode in its enhanced form. Just don't expect many frights.
Stars: 3.5/5
Platforms: Xbox 360, PlayStation 3, PC
Classification: R18


text:
WALTHAM, Mass. — Brandeis University junior center fielder Amanda Genovese (North Haven, Mass./North Haven) stole her 100th and 101st career bases today as the Judges earned a non-conference softball split with Endicott College. Genovese stole the milestone bases in a 9-4 win in game one before the Gulls took the nightcap, 6-1.
Brandeis is now 11-9 on the season after snapping a three-game losing streak in the opener. Endicott is now 9-3.
Genovese sparked the Judges' win in the opener by going 3-for-5 with a double, an RBI and two runs scored. She stole her 100th base in the Judges' three-run bottom of the fourth inning. After driving in tie-breaking run with a double, she stole second and scored on classmate and roommate Anya Kamber's (Sammamish, Wash./Skyline) single that gave Brandeis a 3-1 lead.
Stolen base #100 for Amanda Genovese
Endicott erased that lead with one swing of the bat and some sloppy play in the next half inning. The Gulls, who loaded the bases on a hit batter and two bunt singles, nearly lost the opportunity after Brandeis senior Melissa Nolan (Windsor, Conn./Loomis Chaffee) got a strikeout and a comebacker to the circle that erased a run at the plate. EC's Sam DiBella followed with a single, with two throwing errors on the Judges that allowed all three runners to come plateward. That put the visitors ahead, 4-3.
he Judges responded with a six-run bottom of the sixth inning. Genovese led off with a swinging-bunt single and followed with steal #101. She moved to third on an infield grounder and scored on Kamber's second RBI hit of the day. After sophomore 3B Madison Sullivan (Dover, N.H. / Dover) followed with a double to put two runners in scoring position, junior 1B Cori Coleman (Burr Ridge, Ill./Hinsdale South) laced a ball that the third baseman knocked down, but it rolled away, allowing both runs to score, giving the Judges a 6-4 lead. Three batters later, rookie LF Madison Hunter (Parker, Colo./Legend) blasted her first collegiate home run, a three-run blast to give Brandeis some breathing room. Brandeis rookie Emma Krulick (Maitland, Fla./Winter Park) gave up hits to the first two Gull batters in the seventh, but left them on base to close out the win.
In the second game, Endicott hit two two-run home runs off of Judge junior Nikki Cote (Shelton, Conn./St. Joseph's) to earn the win. Sophomore catcher Emily Hoffman (Malden, Mass./Malden) connected in the fourth inning to break a scoreless tie, while senior Jesse Bilafer (Concord, Mass./Concord Carlisle) doubled the lead to 4-0 in the fifth. Both blasts went to center field.
The Gulls tacked on single runs in the sixth and seventh before Brandeis senior Leah McWilliams (Billerica, Mass./Billerica Memorial) knocked home Nolan to spoil Endicott sophomore Katherine Clark's (Taunton, Mass./Coyle Cassidy) shutout bid.
The Judges return to action Tuesday, April 8, at local rival Lasell for a 3 p.m. start.
- 30 -


text:
MOST professional cricketers go through their entire career without winning the County Championship.
Not Ryan Sidebottom.
The 37-year-old has won five titles – three with Yorkshire (in 2001, 2014 and 2015) and two with Nottinghamshire (in 2005 and 2010).
It is difficult to think of any current player who can match that record.
"I'm just very fortunate," said the former England left-arm pace bowler.
"I'm just very lucky, as a player and individual, to have played with so many great players over the years.
"We've got a great bunch of lads at Yorkshire at the moment, and they help to keep me hungry and fresh.
Download our souvenir poster of Yorkshire's magnificent season in numbers
Video - Andrew Gale interview: Ensuring Yorkshire maintain high standards
Video - Chris Waters: Culture of honesty helps drive Yorkshire to success
Video - Jack Brooks interview PLUS Structure in place for Yorkshire to create modern-day legacy
Video - Dickie Bird: Hard work now steps up for 'marked' Yorkshire
"Touch wood, I can carry on playing for a good while yet and hopefully keep producing the goods."
Sidebottom, who has one year left on his contract, has again led the attack in splendid style.
Despite missing six weeks with injury at the start of the season, he took 41 Championship wickets at 17.90, his prodigious powers showing no sign of abating.
Eleven of those wickets came in a thumping victory against Warwickshire at Edgbaston, where the veteran bowler rolled back the years with a typically talismanic performance.
Sidebottom's match figures of 11-76 were the second-best of his career behind 11-43 against Kent at Headingley in 2000.
"First and foremost, the title has been a wonderful team effort," said Sidebottom, who memorably captured three wickets in the opening over of the match against Middlesex at Lord's – including his 700th in first-class cricket.
"We've played 21 players out of our staff this year because we've lost a lot of players to the England set-up.
"A lot of the Yorkshire lads have come up through the Academy system, and when I came back to the club a few years ago, Martyn Moxon, the director of cricket, said that we've got a lot of young players at the club who are talented and raw, but they keep on improving each and every year.
"To have played alongside those lads and seen them grow during that time has been brilliant, and we can only go from strength to strength in the next few years."


text:
Street Address:
« Back | Forward »
The price of oil is slightly higher as investors remain cautious ahead of the U.S. presidential election. They're also assessing how much demand for oil has dropped in the storm-stricken Northeast.
Benchmark oil rose 31 cents to $85.16 a barrel on the New York Mercantile Exchange. On Friday, oil slumped $2.23 to close at $84.86 a barrel.
Brent crude, which is used to price international varieties of oil, rose 17 cents to $105.85 a barrel on the ICE Futures exchange in London.
AAA says the national average price for gasoline has dropped 7 cents in the past week to $3.47 per gallon. But gas prices have risen slightly since last Monday in New York and New Jersey, where the energy infrastructure was battered by Superstorm Sandy.
Help | Customer Service
Copyright 1995 -
by The Nashville Ledger - All Rights Reserved -
Privacy Policy - About


text:
Magician shows two 8 inch sticks. One stick has a long cord and the other a short cord. When magician pulls the short cord the long cord simultaneously becomes short. This is repeated several times. Audience suspects the cord is connected to the two sticks but magician separates the sticks and the cord still moves as if they were connected.
Do you own this product? Write a review.


text:
- About Pullman
- SEWEDA - Palouse Business...Palouse Life
- Awards and Recognitions
- Pullman Video Tour
- Pullman Transit
- Pullman History
- Downtown parking map
- The Lay of the Land
- Sister City History
- Housing Resources
- Pullman-Moscow Regional Airport
- Neill Public Library
- City Statistics
- Welcome to Pullman
- Greening of Pullman
Sister City History
Last Updated on Wednesday, 24 April 2019 13:00
Ties endure
Pullman Mayor Glenn A. Johnson and Kasai City Mayor Kazuhira Nishimura renewed the friendship affliation between the two cities during a face-to-face meeting in Pullman City Hall on February 6, 2014. The visit also commemorated the 25th anniversary of the sister-city relationship. Mayor Glenn A. Johnson reciprocated the hand of friendship by accepting an invitation to visit Kasai on the occasion of the 1,300th anniversary celebration of the "Harima-no-kuni Fudoki" in May 2015.
Former Pullman Mayor Carole Helm was instrumental in establishing a sister-city relationship with Kasai City of Hyogo prefecture, Japan in November 1989. Kasai City and the City of Pullman were matched because of the many similarities between the agricultural university communities. During the intervening years of the sister-city relationship, both cities have worked hard to establish exchange programs, initially among business owners and more recently for their students. The years of friendship between our cities have been marked by goodwill delegations numbering more than 300 people over the years.
Over the years, numerous Pullman host families established enduring international friendships while housing, providing transportation and sharing meals with their Japanese exchange guests. In addition to time with their host families, the Kasai delegates toured city government services, Washington State University, Pullman Schools and other points of interest. Pullman businesses were generous with token gifts to send home with each guest.
For many years, Pullman and Kasai City alternated sending a chaperoned junior and senior high school delegation to visit. The last trip of Pullman youth ambassadors was during spring break 2007, when the group experienced a cultural exchange in Japan. The most recent Japanese youth delegation visited Pullman in March 23-28, 2019, spending time with host families and at Lincoln Middle School. That was the third youth delegation to visit since 2008.
Japan is divided into 47 prefectures which are administrative units of Japanese government comparable to our states. Hyogo prefecture and Washington state established their sister relationship in October 1963 to work closely on shared government agendas and issues and simultaneously to gain valuable insight and share key information to further strengthen international ties. The Pacific Northwest has active ties to Japan through the sister cities program, business and trade organizations and the Office of the Japanese Consulate in Seattle.
Kasai Mayor Kazuhira Nishimura


text:
Stuffed Chicken Breasts Recipes
Bell Pepper Stuffed Chicken Rolls
This is my second most favorite chicken recipe (after my poulet rôti, "roasted chicken"). The whole idea is to use dark meat from the chicken thigh, stuff it, pan-sear the meat and finish cooking in the oven. It's as simple as that. First, I used boneless chicken (de-boning the thigh and using the bones for excellent chicken broth) and made sure the skin was still on. Then I proceeded with the tender meat. I used a preserved lemon marinade and let it rest overnight. For the filling, I combined roasted red bell peppers, Manzanilla olives, shallots and cornichons (French gherkins).
To me, cooking is an expression of love. The dish doesn't have to be complicated. Learn your basics and you'll be able to dazzle your friends and family with creative, over-the-top dishes by making a few variants of your favorite recipes.
Full Recipe...
Chicken Roulade Stuffed with Morel Mushrooms and Chestnuts
If you're planning on serving poultry on Christmas Eve, you might want to consider this dish. I stuffed chicken with morel mushrooms, caramelized onions and season-friendly roasted chestnuts. I used chicken thighs with the skin on so the meat remained ultra moist and because boning them could be done without difficulty. The whole procedure isn't necessary but it gives the dish an attractive appearance. Once the chicken was cooked, I let it rest for 30 minutes and obtained beautiful slices of chicken roulade.
I'm definitely going to recreate this dish for Christmas, though I'm not sure which poultry I'm going to use. This recipe could be used with duck, pheasant or turkey, but I prefer goose for a holiday feast. You could also use the stuffing of your choice such as sausage, pesto, sun-dried tomatoes, blue cheese, dried cranberries or bread dressing. I can't predict the future but I can tell this is going to be a delicious holiday season!
Full Recipe...
Cheese Chicken Rolls with Fig Chutney
It's already the end of the fig season in our garden. We lucked out this year and gathered so many baskets of delicious figs. One of the best ways to extend the life of quality fruits is to preserve them, so with the last batch, I decided to make fig chutney.
The chutney is very versatile, and I've used it in quite a few dishes. Today I paired it with stuffed chicken rolls. I marinated chicken breasts with Bourbon Barrel Kentuckyaki sauce and stuffed them with goat cheese. All you need is to bake the stuffed chicken for about 30 minutes, then cut it into rolls. I served the white meat with fig chutney that I flavored with Kentuckyaki sauce as well. Here's to a flavorful meal!
Full Recipe...
Olive Tapenade Chicken Rolls
Olive tapenade is extremely versatile and can be used as a spread or filling in many different dishes. You can also use it in place of more traditional party dips such as hummus, guacamole, salsa or roasted bell pepper spread. In this recipe, I added goat cheese to the tapenade and used the mixture as a filling for chicken rolls. I served the dish with a mildly sweet carrot purée that makes an excellent foil to the savory flavor of the tapenade.
If it's not part of your culinary repertoire yet, you should definitely learn to prepare tapenade. It will open up a whole new world of easy to prepare, delectable dishes.
Full Recipe...
Mushroom and Cheese Stuffed Chicken Breast
Mushroom and cheese stuffed chicken breast is a quick and easy chicken recipe for dinner. I used goat ricotta cheese, shiitake mushrooms, sun dried tomatoes and lemon to flavor the meat. Chicken breast can be dry, so I marinated the meat and cooked the chicken for only 15 minutes. It's perhaps more of a roll than a stuffing, but either way, it's delicious.
My mother-in-law is an absolute creature of habit, and when we plan on cooking chicken, her preference is always poulet roti. Contrary to the stereotype, I love my mother-in-law dearly, so don't think I'm complaining, but it takes a miracle to get her to try new things. A couple of nights ago, we had some dinner guests and we had to come up with a main course. We had chicken breasts in the house, but no whole chicken. My mother-in-law was ready to go to the market to get a whole chicken, but I was able to convince her to give this recipe a try.
Given the time crunch, she grudgingly gave in and let me prepare the dish. When she tasted it, she asked me why I haven't made it before! I see a lot of stuffed chicken breasts in my future, and if you try this recipe, I bet you will too!
Full Recipe...


text:
In 1972, the physicist Freeman Dyson wrote an article called "Missed Opportunities." In it, he describes how relativity could have been discovered many years before Einstein announced his findings if mathematicians in places like Göttingen had spoken to physicists who were poring over Maxwell's equations describing electromagnetism. The ingredients were there in 1865 to make the breakthrough—only announced by Einstein some 40 years later.
It is striking that Dyson should have written about scientific ships passing in the night. Shortly after he published the piece, he was responsible for an abrupt collision between physics and mathematics that produced one of the most remarkable scientific ideas of the last half century: that quantum physics and prime numbers are inextricably linked.
This unexpected connection with physics has given us a glimpse of the mathematics that might, ultimately, reveal the secret of these enigmatic numbers. At first the link seemed rather tenuous. But the important role played by the number 42 has recently persuaded even the deepest skeptics that the subatomic world might hold the key to one of the greatest unsolved problems in mathematics.
Prime numbers, such as 17 and 23, are those that can only be divided by themselves and one. They are the most important objects in mathematics because, as the ancient Greeks discovered, they are the building blocks of all numbers—any of which can be broken down into a product of primes. (For example, 105 = 3 x 5 x 7.) They are the hydrogen and oxygen of the world of mathematics, the atoms of arithmetic. They also represent one of the greatest challenges in mathematics.
As a mathematician, I've dedicated my life to trying to find patterns, structure and logic in the apparent chaos that surrounds me. Yet this science of patterns seems to be built from a set of numbers which have no logic to them at all. The primes look more like a set of lottery ticket numbers than a sequence generated by some simple formula or law.
For 2,000 years the problem of the pattern of the primes—or the lack thereof—has been like a magnet, drawing in perplexed mathematicians. Among them was Bernhard Riemann who, in 1859, the same year Darwin published his theory of evolution, put forward an equally-revolutionary thesis for the origin of the primes. Riemann was the mathematician in Göttingen responsible for creating the geometry that would become the foundation for Einstein's great breakthrough. But it wasn't only relativity that his theory would unlock.
Riemann discovered a geometric landscape, the contours of which held the secret to the way primes are distributed through the universe of numbers. He realized that he could use something called the zeta function to build a landscape where the peaks and troughs in a three-dimensional graph correspond to the outputs of the function. The zeta function provided a bridge between the primes and the world of geometry. As Riemann explored the significance of this new landscape, he realized that the places where the zeta function outputs zero (which correspond to the troughs, or places where the landscape dips to sea-level) hold crucial information about the nature of the primes. Mathematicians call these significant places the zeros.
Riemann's discovery was as revolutionary as Einstein's realization that E=mc2. Instead of matter turning into energy, Riemann's equation transformed the primes into points at sea-level in the zeta landscape. But then Riemann noticed that it did something even more incredible. As he marked the locations of the first 10 zeros, a rather amazing pattern began to emerge. The zeros weren't scattered all over; they seemed to be running in a straight line through the landscape. Riemann couldn't believe this was just a coincidence. He proposed that all the zeros, infinitely many of them, would be sitting on this critical line—a conjecture that has become known as the Riemann Hypothesis.
But what did this amazing pattern mean for the primes? If Riemann's discovery was right, it would imply that nature had distributed the primes as fairly as possible. It would mean that the primes behave rather like the random molecules of gas in a room: Although you might not know quite where each molecule is, you can be sure that there won't be a vacuum at one corner and a concentration of molecules at the other.
For mathematicians, Riemann's prediction about the distribution of primes has been very powerful. If true, it would imply the viability of thousands of other theorems, including several of my own, which have had to assume the validity of Riemann's Hypothesis to make further progress. But despite nearly 150 years of effort, no one has been able to confirm that all the zeros really do line up as he predicted.
It was a chance meeting between physicist Freeman Dyson and number theorist Hugh Montgomery in 1972, over tea at Princeton's Institute for Advanced Study, that revealed a stunning new connection in the story of the primes—one that might finally provide a clue about how to navigate Riemann's landscape. They discovered that if you compare a strip of zeros from Riemann's critical line to the experimentally recorded energy levels in the nucleus of a large atom like erbium, the 68th atom in the periodic table of elements, the two are uncannily similar.
It seemed the patterns Montgomery was predicting for the way zeros were distributed on Riemann's critical line were the same as those predicted by quantum physicists for energy levels in the nucleus of heavy atoms. The implications of a connection were immense: If one could understand the mathematics describing the structure of the atomic nucleus in quantum physics, maybe the same math could solve the Riemann Hypothesis.
Mathematicians were skeptical. Though mathematics has often served physicists—Einstein, for instance—they wondered whether physics could really answer hard-core problems in number theory. So in 1996, Peter Sarnak at Princeton threw down the gauntlet and challenged physicists to tell the mathematicians something they didn't know about primes. Recently, Jon Keating and Nina Snaith, of Bristol, duely obliged.
There is an important sequence of numbers called "the moments of the Riemann zeta function." Although we know abstractly how to define it, mathematicians have had great difficulty explicitly calculating the numbers in the sequence. We have known since the 1920s that the first two numbers are 1 and 2, but it wasn't until a few years ago that mathematicians conjectured that the third number in the sequence may be 42—a figure greatly significant to those well-versed in The Hitchhiker's Guide to the Galaxy.
It would also prove to be significant in confirming the connection between primes and quantum physics. Using the connection, Keating and Snaith not only explained why the answer to life, the universe and the third moment of the Riemann zeta function should be 42, but also provided a formula to predict all the numbers in the sequence. Prior to this breakthrough, the evidence for a connection between quantum physics and the primes was based solely on interesting statistical comparisons. But mathematicians are very suspicious of statistics. We like things to be exact. Keating and Snaith had used physics to make a very precise prediction that left no room for the power of statistics to see patterns where there are none.
Mathematicians are now convinced. That chance meeting in the common room in Princeton resulted in one of the most exciting recent advances in the theory of prime numbers. Many of the great problems in mathematics, like Fermat's Last Theorem, have only been cracked once connections were made to other parts of the mathematical world. For 150 years many have been too frightened to tackle the Riemann Hypothesis. The prospect that we might finally have the tools to understand the primes has persuaded many more mathematicians and physicists to take up the challenge. The feeling is in the air that we might be one step closer to a solution. Dyson might be right that the opportunity was missed to discover relativity 40 years earlier, but who knows how long we might still have had to wait for the discovery of connections between primes and quantum physics had mathematicians not enjoyed a good chat over tea. Marcus du Sautoy is professor of mathematics at the University of Oxford, and is the author of The Music of the Primes (HarperCollins).
Originally published March 26, 2006


text:
Laser surgery uses an intense beam of light,
or laser, to burn and destroy the wart tissue. It is usually done in a doctor's
office or clinic.
Local or general anesthetic may be used, depending on
the number of
warts to be removed or the size of the area to be
The wound will be painful for a few
days after laser surgery. Recovery time depends on the location and number of
warts removed.
After laser surgery, call your doctor if you
Laser surgery may be considered
Laser surgery may help when other treatments don't work, but it doesn't seem to work better than cryosurgery or electrosurgery.1
There is a slight risk of infection associated
with laser surgery. Signs of infection include:
Laser surgery:
Complete the surgery information form (PDF)(What is a PDF document?) to help you prepare for this surgery.
CitationsWolff K, Johnson RA (2009). Human papillomavirus infections. In Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology, 6th ed., pp. 787-794. New York: McGraw-Hill.
Last Revised:
September 7, 2012
Healthwise Staff
Medical Review:
Patrice Burgess, MD - Family Medicine & E. Gregory Thompson, MD - Internal Medicine
This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.
To learn more visit Healthwise.org
© 1995-2012 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.


text:
Read the original story in the Portland Tribune here.
A Portland State University professor is spearheading a $50 million health campaign to serve clean water and energy to a quarter of Rwanda's rural population.
The project will distribute water filters and efficient cookstoves to about 600,000 households by next spring, in an effort to reduce the need to boil drinking water and the demand for wood fuel.
The project aims to tackle two of Rwanda's biggest health issues: pneumonia and diarrhea. Dirty water causes the vast majority of disease in Rwanda, where life expectancy is less than 50 years.
"We anticipate this project will bring significant health improvements to these communities and demonstrate the potential to deploy and monitor international health programs like this on a very large scale," says Evan Thomas, the engineering professor who will oversee the distribution of the filters on-site.
About 600 of the filters and cookstoves will be equipped with a remote smart sensor — known as SweetSense — developed by Thomas and his PSU students.
"The sensors help us answer two questions: Does the technology work, and do people use it?" Thomas says. Many international development projects rely on in-person spot checks, making it difficult to collect reliable data and convince donors that improvements will be long-lasting.
"The overall motivation is to improve the sustainability of these programs, through better data collection and more sustained financial mechanisms," Thomas says. The biggest challenge in global development, he says, is often the finite funding for a project without long-term monitoring.
Data from the sensors in Rwanda is sent back in real time to the lab at PSU for students to analyze.
By next spring, 2,000 Rwandese community health workers will distribute water filters and clean-burning cookstoves to serve nearly 3 million people.
According to Thomas, there are 1 billion people worldwide who lack access to clean drinking water, 2 billion who lack access to safe sanitation facilities, and 3 billion who use biomass for their daily energy needs. "These are the leading causes of economic stagnation, illness, and death in many places in the world, and we're able to help address that."
The project will be made possible through the use of carbon credits, each of which equals one ton of carbon dioxide either not emitted or removed from the atmosphere. Companies or countries can then buy those credits to show compliance with the climate-change obligations of the Kyoto Protocols.
Thomas says the carbon price can vary between roughly $5 a credit to as much as $30, depending on the market and the particular project. He anticipates generating several million credits a year, and repaying the project's initial cost over three years, though organizers are still shopping around for potential credit buyers.
The idea is that the cookstoves lower carbon emissions by reducing the need to chop down so many trees, and the water filters reduce the energy needed to boil water.
Indoor air pollution from cookstove smoke has been classified by the World Health Organization as one of the biggest threats to the public health of vulnerable populations in developing countries, leading to nearly 2 million deaths annually.
Every year, 1.5 million people die from diarrhea and other enteric illnesses associated with lack of access to safe drinking water and poor sanitation. Ninety percent of those people are children under the age of 5, most of them in developing countries.
Josh Kefauver, chief operating officer of Manna Energy — the British company implementing the clean water program — calls their work in Rwanda a health campaign to train households on the use of these healthier, cleaner habits.
"It's a really elegant system that we think will seriously benefit the community," he says. Kefauver has been in Rwanda since April, and plans on staying there semi-permanently for the duration of the 10-year program. He is in charge of making individual house calls to find out who will need the filters and cookstoves.
Five AA batteries power each sensor for up to a year while it measures usage and performance. Portland State engineering students have helped develop the sensors over the past year and a half.
Thomas has received $550,000 to commercialize the remote sensors in partnership with Oregon BEST, the Lemelson Foundation, Stevens Water and Mercy Corps, all based in Portland.
Thomas, who is now in Rwanda, will lead a trial distribution of the filters and stoves this fall to 2,000 homes, and begin monitoring usage data. He helped design and implement a similar effort in 2011 that covered 877,000 households in Kenya.


text:
Department of Revenue News Release
May 20, 2014Arnold License Office contract awarded
JEFFERSON CITY - The Office of Administration, in conjunction with the Missouri Department of Revenue, has awarded the management contract for the Arnold License Office to Arnold Jaycees, Inc. All license office contracts in Missouri are awarded through a competitive bid process.
Arnold Jaycees, Inc., has been the contractor of the Arnold License Office since 1976. The Arnold License Office will remain at its current location at 3540 Jeffco Blvd., Suite 120.
In fiscal year 2013, more than 52,000 transactions were conducted at the Arnold office, generating $176,712 in agent processing fees.
All local license offices are overseen by the Missouri Department of Revenue, but each is operated by an independent agent.
Follow the Missouri Department of Revenue on Twitter @MoRevenue


text:
Christmas cinnamon biscuits
These Christmas cookies are great for getting the kids involved in cooking, and they will look great on the tree too
Nutrition and extra info
- Freezable
- kcal119
- fat4g
- saturates2g
- carbs20g
- sugars11g
- fibre0g
- protein2g
- salt0.18g
- 175g dark muscovado sugar
- 85g golden syrup
Golden syrupgoal-dun sir-rup
Golden syrup is a clear, sparkling, golden-amber coloured, sweet…
- 100g butter
Butter is made when lactic-acid producing bacteria are added to cream and churned to make an…
- 3 tsp ground ginger
- 1 tsp ground cinnamon
- 350g plain flour, plus extra for dusting
- 1 tsp bicarbonate of soda
Bicarbonate of soda
Bicarbonate of soda, or baking soda, is an alkali which is used to raise soda breads and full-…
- 1 egg, lightly beaten
The ultimate convenience food, eggs are powerhouses of nutrition, packed with protein and a…
To finish
- 100g white chocolate
White chocolatewhy-t chok-lit
To purists, this is not chocolate because it is made only from the fat or butter of the cacao…
- edible silver balls
Heat the sugar, golden syrup and butter until melted. Mix the spices and flour in a large bowl. Dissolve the bicarbonate of soda in 1 tsp cold water. Make a well in the centre of the dry ingredients, add the melted sugar mix, egg and bicarbonate of soda. Mix well. At this stage the mix will be soft but will firm up on cooling.
Cover the surface of the biscuit mix with cling film and leave to cool, then put in the fridge for at least 1 hr to become firm enough to roll out.
Heat oven to 190C/170C fan/gas 5. Turn the dough out onto a lightly floured surface and knead briefly. (At this stage the dough can be put into a food bag and kept in the fridge for up to a week.) Cut the dough in half. Thinly roll out one half on a lightly floured surface. Cut into shapes with cutters, such as gifts, trees and hearts, then transfer to baking sheets, leaving a little room for them to spread. If you plan to hang the biscuits up, make a small hole in the top of each one using a skewer. Repeat with remaining dough.
Bake for 12-15 mins until they darken slightly. If the holes you have made have closed up, remake them while the biscuits are warm and soft using a skewer. Cool for a few mins on the baking sheets, then transfer to a wire rack to cool and harden up completely.
Break up the chocolate and melt in the microwave on Medium for 1-2 mins, or in a small heatproof bowl over simmering water. Drizzle the chocolate over the biscuits, or pipe on shapes or names, then stick a few silver balls into the chocolate. If hung up on the tree, the biscuits will be edible for about a week, but will last a lot longer as decorations.


text:
Sugar & Plumm is a homemade sweets boutique, cafe and bakery where you can get anything from candies to sundaes to chicken and waffles to a "Bee Hive"--you'll soon find out what that is! It's a whimsical wonderland of treats to please all tastes. We talked to Lamia Jacobs, founder and CEO of the new tasty spot in Paramus, NJ (and soon to open in New York next year).
How did you come up with the concept of Sugar & Plumm?
Since I moved to America from Paris, I've been searching for a place where I could take my kids and my friends for a nice, relaxing meal any time of the day. That's when I realized I had to be the one to make it happen!
What are some of the most popular items with your clientele since opening?
The most popular treats are the French macarons and cake pops. The chicken & waffles and buckwheat crepes are also customer favorites.
Sugar & Plumm is described as an "imaginative wonderland." What are some of the more "imaginative" creations offered?
Our custom cakes and seasonal chocolate sculptures can be made to look like virtually anything, but it's our sundaes that wow customers on a daily basis. We serve our ice cream in deep goblets piled with whipped cream, homemade sauces, and more unusual toppings like meringue batons and vanilla crumble. They're beautiful to look at and really show off the whimsical side of our pastry kitchen.
Why did you decide to open in New Jersey before your New York City stores (scheduled to open in 2012)?
When I first came to New Jersey I was pleasantly surprised by how bustling it was, but also knew it needed a spot where the locals could enjoy quality desserts and a serious savory menu as well. The Bergen Town Center just seemed like the perfect location: always busy and filled with families from Bergen County looking for something fun to do and good to eat.
We recently had an episode themed "favorite things between two buns"--do you guys offer anything that could fall into this category?
Yes, we serve a very popular "Plumm Burger" made with dry-aged beef, white cheddar, smoked bacon and plum tomato jam, mini sliders on our kids menu and a "foot long" Angus beef hot dog with house mustard, relish and onion.
What's your personal favorite thing on the menu?
The French macarons! I eat a pistachio and a licorice macaron every day, even for breakfast! On the savory menu, I can't resist the buckwheat crepes and usually have them for lunch.
Our "unique eats" episode is airing next week. How does Sugar & Plumm offer a unique dining experience?
Sugar & Plumm offers a unique dining experience in that it combines shopping, dining and dessert in one setting. Guests are free to shop the candy and toy section while they wait for their meal or watch crepes and sundaes being made before their eyes. As for a unique dish, we serve a plated dessert called the "Bee Hive." It looks like a classic hive, but it's made from swirls of meringue with an ice cream center--a new take on the baked Alaska.
Catch 1st Look Saturdays on NBC after Saturday Night Live. And, don't miss the "unique eats" episode on November 19, 2011.


text:
Novo Style Tempered Glass Guard for Samsung Galaxy J2 Prime, Samsung Galaxy J2 Ace(Pack of 1)
Price - Rs. 110
product description
- Anti Explosion Tempered Glass Screen Protector for Samsung Galaxy J2 Ace / Samsung Galaxy J2 Prime is from Novo Style processed glass for anti-scratch and anti-shock protection.
- The back of each screen is covered with a strong silicon adhesive for easy installation and prevention of any gaps between your device and the screen protector, this ensures the touch sensitivity of your screen is not affected.
you may also like
Screen Protectors
- By name
- By colour


text:
Storage Virtualization
Storage Virtualization refers to the process of completely abstracting logical storage from physical storage. The physical storage resources are agregated into storage pools, from which the logical storage is created. With storage virtualization, multiple independent storage devices, that may be scattered over a network, appear to be a single monolithic storage device, which can be managed centrally. Storage Virtualization is commonly used in SANs.


text:
Will County Public Defender
Employees of the Will County Public Defender's Office will accept all appointments from the Judiciary of the Twelfth Judicial Circuit and provide competent and professional legal services to the indigent citizens of Will County, while adhering to the highest standards of ethical conduct. Our office will strive to protect the fundamental rights, liberties, and dignity of each person whose case has been entrusted to us.
To find out if you qualify for a public defender and more information on their office and services, visit their website: