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Memphis, Tennessee – Early treatment response is a powerful predictor of long-term outcome for young patients with acute myeloid leukemia (AML). The information can help physicians decide whether a more intensive approach is needed. Research led by St. Jude Children's Research Hospital investigators has identified the best test for measuring that response and guiding therapy.
The method uses a laboratory technique called flow cytometry, which makes it possible to identify a single cancer cell in 1,000 normal cells that remain in patient bone marrow after the initial intensive weeks of chemotherapy. St. Jude investigators were instrumental in developing the test for identifying very low levels of cancer called minimal residual disease.
An analysis published in the September 10 online edition of the Journal of Clinical Oncology showed that checking for minimal residual disease by flow cytometry was better than two other widely used methods for predicting patient survival. The results help identify who might benefit from more intensive therapy, including bone marrow transplantation.
"These results will help establish flow cytometry testing for minimal residual disease as a routine tool for guiding therapy of acute myeloid leukemia and identifying patients early who are at risk of treatment failure," said Hiroto Inaba, M.D., Ph.D., an associate member of the Department of Oncology at St. Jude. He is the study's first and corresponding author.
Flow cytometry uses a laser to help distinguish cancer cells from normal cells based on different cell surface markers and other molecules. Dario Campana, M.D., Ph.D., led the successful St. Jude effort to develop the test about 15 years ago. Campana, now at the National University of Singapore, is the paper's senior author.
Such testing is widely used to guide treatment of the most common childhood cancer, acute lymphoblastic leukemia (ALL). AML targets different white blood cells than ALL does. AML also affects fewer children and adolescents, about 500 annually in the U.S., and has a lower survival rate. Although 94 percent of St. Jude ALL patients can now look forward to becoming long-term survivors, the figure is 71 percent for young AML patients.
AML treatment response is evaluated on day 22 of therapy as well as at the end of each treatment phase and serves as a powerful predictor of patient survival. The results are used to guide ongoing therapy and identify patients who are candidates for more intense treatment.
For decades, physicians have relied on the microscope to evaluate patient response to therapy. Patients are considered to be in remission if a bone marrow examination finds cancer cells account for fewer than five in 100 cells. Flow cytometry and another laboratory technique called polymerase chain reaction (PCR) were also developed to help gauge treatment response. PCR is used to monitor genes created when chromosomes break and swap pieces. The genes are found in about half of all pediatric AML cases.
This study is the most comprehensive effort yet comparing the power of the three approaches to predict the AML treatment outcome. The work involved 203 AML patients enrolled in a clinical trial called AML02. St. Jude led the multi-institution study of young AML patients whose disease was diagnosed between 2002 and 2008. The project marked the first time minimal residual disease was used to guide therapy. During the study researchers examined 1,514 patient bone marrow samples by flow cytometry. Of those samples, 1,382 also had information regarding microscopic evaluation and 508 of PCR testing.
The analysis showed that minimal residual disease measured by flow cytometry was an independent predictor of patient outcome. Finding even one leukemia cell in 1,000 normal cells in bone marrow after the first or second round of therapy was associated with a worse prognosis and a greater risk of relapse or treatment failure.
Researchers concluded microscopic examination had limited value for gauging treatment response. Problems ranged from an inability to distinguish between cells destined to become leukemia cells and normal blood cells to classifying about 10 percent of patients as being in remission when flow cytometry identified leukemia cells in the same bone marrow.
Investigators also concluded that flow cytometry rendered PCR testing unnecessary for most AML patients. The analysis found PCR testing generally overestimated the presence of leukemia cells. In this study, PCR identified 197 of 311 patient samples as containing leukemia cells. Flow cytometry of the same samples showed just 19 actually harbored detectible minimal residual disease. Researchers did find PCR testing valuable in predicting outcome and guiding therapy for a subgroup of AML patients with mixed lineage leukemia (MLL) gene changes.
The other authors are Elaine Coustan-Smith, National University of Singapore; Xueyuan Cao, Stanley Pounds, Sheila Shurtleff, Susana Raimondi, Jeffrey Jacobsen, Raul Ribeiro, Wing Leung, James Downing, Ching-Hon Pui and Jeffrey Rubnitz, all of St. Jude; Kathleen Wang and Mihaela Onciu, both formerly of St. Jude; Gary Dahl, Lucile Packard Children's Hospital and Stanford Cancer Center, Palo Alto, CA.; W. Paul Bowman, Cook Children's Medical Center, Fort Worth; Jeffrey Taub, Children's Hospital of Michigan, Detroit; and Barbara Degar, Dana-Farber Cancer Institute, Boston.
The research was supported in part by grants (CA115422, CA023944 and CA021765) from the National Cancer Institute at the National Institutes of Health and ALSAC.
St. Jude Children's Research Hospital
Since opening 50 years ago, St. Jude Children's Research Hospital has played a pivotal role in pushing overall U.S. pediatric cancer survival rates from 20 to 80 percent. Founded by the late entertainer Danny Thomas, St. Jude is the first and only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children. St. Jude is also a leader in research and treatment of life-threatening blood disorders and infectious diseases in children. No family ever pays St. Jude for the care their child receives. To learn more, visit www.stjude.org. Follow us on Twitter @StJudeResearch.
St. Jude Media Relations Contacts
Summer Freeman
(desk) 901-595-3061
(cell) 901-297-9861
Carrie Strehlau
(desk) 901-595-2295
(cell) 901-297-9875


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Sterling Hayden
"There is not enough money in Hollywood to lure me into making another picture with Joan Crawford. And I like money."
— Sterling Hayden, after completing the western drama Johnny Guitar (1954)
Her roles were largely stereotypical, yet her charm and goofiness made her memorable. Here's a look at her work beyond Gone With the Wind.
DESIGN IN FILM: THE MODERN HOUSEAn eight-minute video montage of modern homes—real and fake—as seen on the silver screen.
An examination of the lengthy career of the Chinese-American character actor, from Charlie Chan to Woody Allen.
70MMThirty visually stunning films that illustrate the grandeur of large-format filmmaking.
Our look at the Texas actor's 43-year film career, including an ill-advised Oscar campaign.
A look at the professional life of an actress who proved to be much more than just the Wicked Witch of the West.
NEBRASKANSA look at some of the memorable talents—from Astaire to Zanuck—to come from the Cornhusker State.
Twenty-five cool photos reveal what goes on outside of movie camera range.
Our list of at least a dozen silent film performers that are happily still with us.
12 GREAT MOVIE SONGSElvis, The Beatles and The Supremes join our list of favorite movie themes of the 1960s.
WILHELM SCREAMWe trace the history of one of the most famous and beloved sound effects in movies.
LOST HORIZONA dud receives its due as we explore the elements that made this 1973 musical so preposterously memorable.
One hundred films whose final words of dialogue make indelible lasting impressions.
25 GREAT SILENT MOVIE POSTERSOur selection of artwork from the early days of motion pictures that expertly illustrate the tone and tale of the films they represent.
RAVES AND RASPBERRIES We select some choice bits from reviews by the late Roger Ebert.
ERROL FLYNN GETS WHACKEDThe actor recalls an unforgettable moment with Bette Davis on the set of The Private Lives of Elizabeth and Essex.
CINEMATIC RIDESTen films where carnival attractions add to the plot and give their protagonists a cheap thrill.
Three overwrought cautionary tales from the 1930s examine the perils of smoking marijuana in polite society.
20 DIRECTORS / 20 FILMSSome of the world's best moviemakers from Hollywood's Golden Era provide a behind-the-scenes look at their creations.
HENRY MANCINIWe take a look at three of the famed composer's catchiest and most enduring works.
LOS ANGELES IN THE 1920SVintage clips offer a look at famous boulevards, studios, theaters, eateries and more.
BILLY WILDEROur favorite lines of dialogue from the Oscar-winning writer/director.
WOODY ALLENChoice lines of dialogue, from Take the Money and Run to Midnight in Paris.
KATHARINE HEPBURNTen authoritative moments when Kate's movie character speaks her mind.
UFA MOVIE POSTERSA look at the early one sheets from the longest standing film studio in Germany.
THE LANGUAGE OF NOIRWe celebrate tough talk from the best of Hollywood's gritty crime dramas.
Aerial shots of Hollywood in 1958 includes Griffith Observatory, Grauman's Chinese Theater and major studios.
AMERICAWe celebrate one of the most exuberant dance numbers committed to film, a thrilling showcase for freakishly talented folks with music in their bones.
HOLLYWOOD POSTCARDSTen vintage postcards revealing the glories of Southern California's movie mecca.
MAJOR FILMS, MINOR GAFFESTwenty-five mistakes in some of the greatest movies ever made.
GEORGE GERSHWINTen classic songs as seen on the silver screen.
GREAT ENDINGSA memorable tussle in Death Valley caps Erich von Stroheim's broken classic.
10 GREAT POSTERSOur look at striking works of art that just happen to sell movie tickets.
MUST READMGM: Hollywood's Greatest Backlot provides a fascinating look at a lost treasure.
IN THE COOL, COOL, COOL OF THE EVENINGJane Wyman and Bing Crosby charm with the Oscar-winning song from Here Comes the Groom (1951).
PLUNDER ROADFilm noir at its best—and most economical. No backstory, a lean look and just 72 minutes long.
W.C. FIELDSTen of his most memorable character names.
Aliens and mutants take center stage in twenty-five spectacular movie posters from the 1950s.
Our list of ten must-see films—ten artful depictions of the human condition—by one of the world's most influential directors.
Accomplished directors from the past 50 years talk about their triumphs and challenges in bringing a story to the big screen.
We single out five films that display the talent and range of the Warner Bros. character actor.
AL HIRSCHFELDWe select our ten favorite movie posters by the famed caricaturist.
Five films that best represent the fluttery voiced character actress's charms.
DIAMOND SETTINGSWe take a look at five of our favorite baseball movies of the '40s and '50s.
A dozen books that became publishing phenomena and, at times, well-made and popular films.
SCREEN TESTSAudition footage from Monroe, Dean, Brando and others.
MOVIE MOMENTS THAT MAKE LIFE WORTH LIVINGOur collection of ten little moments of breathtaking beauty, expert craftsmanship and happy accidents that rank as our favorites.
A tribute to a character actress who's made aunts and spinsters her specialty.
STARS ON STARS: 30 CANDID OPINIONSA collection of favorite quotes from movie folk discussing their peers.
We take a good look at the work of MGM's legendary art director.
JOHN QUALENFive of our favorite performances from the character actor's lengthy career.
We select three movie musicals we deeply wish the sunny singer/actress would have made.
Twelve examples of what made the late actor such an enduring movie star.
Ten artful, playful and downright silly shots from some of the most famous movies in existence.
JEFFREY HUNTERWe tip our hat to the underrated (and very pretty) actor best known for going toe-to-toe with John Wayne in The Searchers and hanging on the cross in Nicholas Ray's King of Kings.
ELVIS PRESLEYFive essential films for the Elvis movie fan.
We take a closer look and listen at Johnny Mercer's witty ditty about the coming of the season.
BILL GOLD'S MOVIE POSTERSOur salute to the legendary graphic artist, including 25 of his posters for some of the most famous movies ever made.
BEAUTIFUL MENFilm giants Cary Grant and his ilk will have to wait. Here we look at ten not-so-obvious choices—actors blessed with incredible good looks, if not legendary status.
BEAUTIFUL WOMENTen of the most physically stunning females to grace the silver screen.
FOOTBALLFive classic films where gridiron shenanigans drive the plot.
THE 43 FACES OF JOHNNY DEPPWe review the wide variety of characters the actor has played, from early teenager roles to larger-than-life eccentrics.
FRED ASTAIREFive lively numbers from the peerless hoofer.
THE ROAD TO HELEN LAWSONJudy Garland, Susan Hayward and the bumpy road Valley of the Dolls producers experienced in casting an important role in a truly lousy film.
AMERICAN LANDMARKS ON FILM From the Empire State Building to the Golden Gate Bridge, we take a look at ten famous sights that added drama to the movies.
THE GIRL HUNT BALLETWe revisit the stylish Fred Astaire dream ballet from The Band Wagon (1953).
IOWA FILMS & STARSTen contributions the Hawkeye State has made to motion picture history.
FOX THEATEROur fond look back at one of San Francisco's grandest movie palaces.
AUTOBIOGRAPHIESTen great titles penned by industry legends.
THE BAND WAGONNanette Fabray recalls a glaring mistake in the 1953 classic musical.
TRIGGERWe celebrate the life and somewhat creepy afterlife of Roy Rogers's favorite mount.
CHARACTERS: AGNES GOOCHPeggy Cass's memorable turn as a plain Jane coaxed into living a little in Auntie Mame (1958).
DESIGNS ON FILMA handsome volume by author and designer Cathy Whitlock chronicles the history of Hollywood set design.
REBECCAFive screen tests for Hitchock's 1940 classic, with comments by David O. Selznick.
CHARACTERS: BABY ROSALIEIn a daffy send-up of Shirley Temple, June Preisser plays an aging child star in MGM's let's-put-on-a-show musical, Babes in Arms (1939).
PRESTON STURGESSnippets of dialogue from six of the writer/director's best films.
ANSELMO BALLESTEROur gallery of ten striking one sheets from the Italian poster artist.
GREAT MOVIESCelebrating the cool jazz short, Jammin' the Blues (1944).
BETTY HUTTONTwelve films that exemplify the charms of this freakishly energetic performer.
JOSEPH L. MANKIEWICZSmart dialogue from the Oscar-winning screenwriter.
DESERT NOIROur report from this year's Arthur Lyons Film Noir Festival in Palm Springs.
RED DREAM FACTORYWe profile eight films from a unique Russian-German film studio of the twenties and thirties.
"There is not enough money in Hollywood to lure me into making another picture with Joan Crawford. And I like money."
— Sterling Hayden, after completing the western drama Johnny Guitar (1954)

subset: commoncrawl


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San Francisco Park
Oviedo Cathedral Square
Santa María del Naranco Church
Right in the heart of Oviedo we find San Francisco Park. A garden with wide avenues, peaceful paths and beautiful monuments where you can enjoy the scent of plants, the sound of fountains and the pleasant company of peacocks which freely guide visitors during their walks.
This old kitchen garden belonged to the San Francisco Convent and in the 19th century it became a large public garden of 90,000 square metres in the very centre of Oviedo. To explore this park is to discover another world, a paradise of leaves, flowers, branches and trees with a wide variety of flora.
To get the feel of this park, you should take a gentle stroll over its many trails, while contemplating all that surrounds you on the way. This is the only way to discover the magical spots hidden by the thick vegetation, its winding paths and broad avenues, illuminated by lampposts as the sun sets. Amidst banana, oak, elm and chestnut trees, there are numerous monuments, statues and arches, including the Romanesque main facade of the old San Isidro church, an 18th century Neoclassical couch called the Silla del Rey and a piece dedicated to the splendid writer Leopoldo Alas Clarín, who lived in Oviedo.
Stop time with a visit to the rose garden (an explosion of colour in spring), listening to the water running from the Angelín Fountain, or breathing deeply at Covadonga Lake. Visitors will imagine they have travelled back in time to an era of horse-drawn carriages, duels at dawn and people dressed in cloaks and hats.
Peacocks walk freely through the park and accompany visitors during their strolls. Watching their wings spread out, an array of colour and hue, is a spectacular sight. These are not the only animals living in this urban natural space. Ducks and swans rest in the pond, whilst birds fly through the treetops and even an owl, elusive and mysterious, acts as improvised night-watchman.
We suggest a stroll along the Curas or Bombé walks, where you will find the Las Ranas and La Fuentona Fountains, breathe in the peace of the Herradura avenue or enjoy the Álamos walk where the popular Book Fair is celebrated in spring. However, it is in autumn when the San Francisco Park acquires its maximum splendour, rich with incredible colours, beautiful ochre and golden tones filling the air with nostalgia and the scent of moisture.
At the end of the wood Oviedo awaits, capital of Asturias, a beautiful city with an historic pedestrian centre where the cathedral stands out with its impressive Gothic tower. A stroll through its busy, narrow streets, contemplating pre-Romanesque churches, such as Santa María del Naranco and San Miguel de Lillo, designated World Heritage Sites, and admiring noble buildings like the Town Hall, Camposagrado Palace, Conde de Toreno Palace or the beautiful University is not to be missed. And, of course, we suggest you stop to relish the Asturian cuisine, with specialties such as Cabrales cheese, fabada (sausage and bean casserole) pote asturiano (regional stew with beans, potatoes, greens and meat) or the delicious cider, to mention but a few examples.
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Colo. revenue continue to grow, economists say
DENVER – Economists say taxes on stock sales continues to be an economic driver in Colorado and the state's revenue is expected to be higher than expected this budget year.
Economists from Gov. John Hickenlooper's office say the tax receipts are expected to be $548.2 million, or 7.1 percent higher, this budget year than the prior year. The state's general fund is expected to be $8.3 billion for the fiscal year that began in July.
The quarterly forecast released Monday afternoon will play a key role in the upcoming debate over the budget. Lawmakers typically give final approval to the budget next month.
Recent forecasts have shown a trend of steady growth. The general fund now exceeds the pre-Great Recession peak of $7.7 billion in 2007.
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Last week, Members of Congress called big oil executives to the stand to defend the high profits their companies are making. Some in Congress are using high oil profits as a reason to propose eliminating what they label "oil subsidies," despite the fact that what they call subsidies are broadly available tax breaks. You can get a breakdown in this paper: "What's an Oil Subsidy?"
President Obama did the same in his weekly address. Even actor Leonardo DiCaprio is getting into the action, recently tweeting, "Big oil is making huge profits & getting billions in US taxpayer subsidies. End #oilsubsidies."
The irony of course is that DiCaprio, a successful beneficiary of our system of free enterprise, ignores its strengths and virtues by demonizing profit. These attacks are misinformed and off-base. Demonizing profits ignores why profits matter and the ways free enterprise benefits all Americans. It also ignores the fact that oil and natural gas industry earnings, against their sales, are in line with other manufacturers and are in fact below the manufacturing average.
So while it's easy for some politicians and outraged denizens of Hollywood to blast high profits for oil companies at a time when families are struggling, the reality is that profits are an integral part of our economy, including the oil industry.
- Profits act as a rainy day fund. All companies have good years and bad years. High profits in one year can cushion the blow in another so a company won't have to move through bankruptcy or ask for a government bailout. Oil profits vary from year to year with the price of oil. The price of oil is global; it goes up and down based on many factors. In 2008, oil prices were high, and companies made higher profits. The opposite holds true for 2009. According to the Energy Information Administration, "Oil and natural gas production continued to be the most profitable business segment, contributing $42 billion in net income, but this was a decline of 43 percent from 2008. Return on net investment in place (ROI) fell to 7 percent in 2009 from 13 percent in 2008." Increased demand for oil as countries recover from the global recession is driving the price of oil—and consequently profits—back up. If and when the price falls in the future, firms can use these profits to tide them over.
- Profits encourage new investment. In Russ Roberts's book The Invisible Heart, Sam, an economics teacher, pulls out a dollar on the first day of class, sets it on the front desk, and tells the class that the first person who gets to the dollar gets to keep it. It takes a second before a student rushes up to claim the dollar, but when Sam does it again, half the class jumps out of their seats. The simple lesson is that profit opportunities motivate effort. In the energy industry, profits motivate oil companies to take risks and make new investments in newer and more efficient equipment. Companies invest so they can extract oil and gas from the ground in ways that are safer and more cost-effective. Profits reward good investments just as losses punish bad investments (unless they receive a government bailout). Profits also allow businesses to hire more workers and increase wages.
- Profits help people. The adage "people, not profits" is a ridiculous one. When politicians attack the billions in profits that oil companies make, it's important to remember who owns these companies and where that money goes: to the American people. According to the American Petroleum Institute, mutual funds and other firms hold almost 30 percent of oil stocks. Pension funds hold 27 percent, individual investors hold 23 percent, 14 percent is held in Individual Retirement Accounts, other institutional investments hold 5 percent, and corporate management holds just 1.5 percent. Increasing the supply of oil not only helps lower prices and produce jobs—it also helps boost stocks, mutual funds, IRAs, and pension funds owned by millions of Americans.
Profits play a critical role in our economy and reward producers for creating value for consumers. In a new video entitled "The Morality of Profit," the Atlas Network's Vice President for International Programs Tom Palmer asks, "Did Bill Gates violate anyone's rights when he organized Microsoft and brought computer programs to billions of people? No, he offered customers value and free exchange."
The same is true for oil. Consumers value oil and will move away from it when a better alternative exists. Politicians who demonize profits are missing the nature and the importance of the profit–loss system.


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Baby Get Back: 5 Tips for Getting Through Sickness and Setbacks
Our monthly mommy blogger reports from the front lines of having your comeback sidelined by sickness.
by Megan Evoe
The saying "an apple a day keeps the doctor away" is just that, a saying. A bunch of words that do not magically keep people from becoming sick. I actually do eat an apple—accompanied by a gluttonous helping of peanut butter—every day as my mid-morning snack; still, nothing could prevent me from the swirling sickness in Boulder.
What started as a simple cold quickly turned into a suffocating illness that left me feeling dizzy, exhausted, and not able to push through my training. For five full days, I did nothing but walk on an incline on my treadmill while my kids napped in the afternoon. Usually, workouts make me feel better and tend to open my nasal passage when I am stuffed, but this time, I was wrecked. I even had to resort to terrible table manners and chew with my mouth open so I could breathe when I ate. My two-year old was quick to remind me to chew with my mouth closed—I took this as a positive sign that he actually listens to me. Winning!
Just as I was starting to feel better a week later , the black cloud of sickness quickly followed both my six month old and two-year-old, making the month of March one germ-filled, doctor-visiting, sleepless whirlwind.
We've made it out on the other side in one piece, healthy and happy, but it was definitely my worst month of training yet. Below, I have put together some survival strategies if you're currently facing the same demons.
Take it easy
Although the cold hit me hard for only one full week, I didn't actually feel like training until two weeks had gone by. I got in some workouts the week following my illness, but I still felt lethargic and like I was running out of gas, even in my easier workouts. The workouts were the least of my worries as I still have an energetic two year old and baby who need me all day long.
After complaining that I was completely exhausted, Pat, my husband and coach, reminded me that it's normal not to feel great immediately after being sick. He also reminded me that taking care of the kids all day is not a restful situation, and that I just needed to let my energy come back slowly. As usual, he was right.
→ A mother's wisdom: Make sure you aren't overexerting yourself in workouts, and just do what you can.
Make time
Like I said in my first post, I'm a mom first, so when my kids are sick and out of their normal, daily routines, my training comes a distant second. It was almost comical: one kid would finally go down for a nap, the other one would wake up, leaving me no free time during the day. I found myself getting up super early to squeeze in a run, a weight session, or a trainer session in our basement before my sick kiddos woke up. It's not my first choice of when or where to train, but I knew I wouldn't get it done otherwise. I am the first to admit that I am worthless in the evenings after we get the kids to sleep. It's a Christmas miracle if I stay awake through Scandal, which ends at 9 pm. Parenting will put you to sleep fast!
→ A mother's wisdom: Be creative in fitting in training. You'll be glad that you made the small sacrifices to chase your goal, no matter how small or insignificant the session.
Recharging your batteries
After two weeks of not feeling well myself, then two more weeks of taking care of my kids, I was rundown physically and emotionally. I am a consistently healthy eater, but I know I was just grabbing whatever was convenient or not eating enough during the craziness of the days. Finally, over the last week, I finally started to pay attention to what I was eating and making sure I was getting enough calories so that I was fueled, not only for workouts, but for motherhood. I know a lot of parents that will "forget" to eat during the day because they are running around with their kids and completing the laundry list of tasks for the day. I can tell that my workouts are already improving since I have taken charge of what's on my plate and I am not slumped over while playing Lego with my son by mid-afternoon.
→ A mother's wisdom: Prioritize habits like good nutrition, sleep, and recovery, especially during times of illness and injury.
Kill yourself with kindness
The hardest thing as a mom, for me, is being kind to myself. I never give myself a pass for much on the day-to-day basis. This last month, my training was basically put on the back burner as the laundry piled up in every bedroom. I knew one of the hardest tasks for me during my training was to be nice to myself when the going got tough, but dealing with illness and two sick kids this month took it to the next level.
Now that the house is completely disinfected, the laundry is done, and my kids have their spunk back, I realize everything always comes back around and that being kind to myself is much easier than being harsh.
→ A mother's wisdom: Take extra time to baby yourself with whatever it is you need...naps, workouts, or small indulgences to remind yourself that you're worth it!
Remember, every little bit counts
Even though my training wasn't full-on this month, I have to keep in perspective that I still trained. Yes, I took five days away from swimming, biking, and running when I was sick, but I still kept moving and made some gains. I had many moments where I questioned completing IRONMAN 70.3 Boulder, but thankfully, Pat reminded me that I have plenty of time until race day and to just get healthy and move forward. I knew I hired him as a coach for a reason!
It turns out there are a lot of good things to focus on. I am actually up in the double digits for my long run—mileage I haven't reached since the summer after having my son. I love the runner's high I have every Saturday after a long, social run with new and old friends. I am also not feeling like a pig-in-a-blanket when I put my swimsuit on anymore as the baby weight is almost gone. Anyone who's had a baby knows the euphoria of these moments when clothes fit better and you know you are making fitness gains. This month may have started out on the wrong foot, but it ended with gratitude and a new perspective.
→ A mother's wisdom: Keep your perspective by seeing the big picture. This is only a blip on the screen, and you are still building fitness and resilience, even through momentary setbacks.
Megan Evoe is a freelance sports journalist and lifelong athlete. She lives in Boulder, Colo. with her husband, Patrick, and two children.
Baby Get Back: 1 | Baby Get Back: II | Baby Get Back: III


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A Proud Tradition of Academic
and Athletic Excellence!
Fight on
with mighty Triton Spirit,
Hail to, the Triton name.
Loyal Tritons
march victorious,
On to fame.
Fight on,
The Triton host prevails,
March on, in unity --
Bold and strong we fight
for Triton victory.
This is UC San Diego Athletics...
- Triton teams have captured 30 national championships while 44 squads have finished as national runners-up and 49 others have achieved national third-place honors. All told, UC San Diego has won 276 national, regional, and conference championships.
- UC San Diego scholar-athletes have won 138 individual national championships.
- A remarkable 1,389 Tritons have been named to All-America teams, including 41 in 2018-19.
- UC San Diego scholar-athletes have excelled academically as well, earning 37 prestigious NCAA Post-Graduate Scholarships and 82 Academic All-America selections. Consistently, over 55 percent of scholar-athletes earn a cumulative GPA of 3.0 or higher, placing them on the Athletic Director's Honor Roll.
- In 2018-19, UC San Diego posted a 2nd-place finish out of 268 NCAA Division II schools in the Learfield Directors' Cup, an award emblematic of the best overall athletics department in the country. It marked the fourth-straight year that UC San Diego placed in the top 10. Since moving to the NCAA Division II level for the 2000-01 academic year, UC San Diego has placed in the top seven programs in the country on 13 different occasions and has finished second overall three times.
- UC San Diego won its eighth California Collegiate Athletic Association Commissioner's Cup title in 2018-19, an award symbolizing the best overall athletics department in the prestigious conference.
- For eight straight years from 2007 to 2014, UC San Diego was ranked first in Division II in the National Collegiate Scouting Association Power Rankings, which are based on student-athlete graduation rates, academic strength, and athletic prowess of the university.
updated 7/11/19


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Useful Resources
Please find a list of recent project outputs here:
- ITELab Briefing Paper
- ITELab Case Studies 2018
- ITE Monitoring Report 2018
- ITELab Brochure
- Case studies 2019
- Student Voice Report
- Student Voice Charter
- Recommendations and resources to support innovation within ITE
For more information please contact:
or directly the ITELab Project Manager: Dorothy Cassells, European Schoolnet: email@example.com
Follow us on Twitter: #ITELab_eu
Follow the ITE Student Voice here.
The newsletter includes news from the Future Classroom Lab, ITELab and other related projects. Click here to subscribe >>
ITELab (Initial Teachers Education Lab) is a Knowledge Alliance project between higher education institutions and industry to foster innovation and knowledge exchange in initial/preservice teacher education (ITE). The ITELab Knowledge Alliance project includes six universities providing teacher education, of which five will pilot the modules and student MOOC and one will act in an evaluation capacity. Project partners also include four companies that offer Information and Communications Technology (ICT) solutions and professional development for teachers.
ITELab is co-ordinated by European Schoolnet, a pan-European network of 31 Ministries of Education concerned with the transformation of teaching and learning in schools. European Schoolnet's work in previous projects with Ministries of Education, plus a needs analysis carried out with teacher educators highlighted, that the way in which student teachers currently receive training on ICT is a key roadblock related to the mainstreaming of innovative pedagogical practice that involves ICT. There is also a 'disconnect' between ITE and continuing professional development (CPD) and, as a consequence, in-service training on the pedagogical use of ICT is increasingly required to equip teachers with the essential competences that they did not acquire during their initial training.
Universities and companies will come together in ITELab and work with Ministries of Education, national ICT agencies and other stakeholders (participating as Associate Partners), to address these issues. The project will provide data and case studies that highlight new approaches to integrating ICT within ITE courses and the challenges that still need to be addressed in order to boost innovation in this area within higher education. Based on this work, the project will develop new course modules and a MOOC for student teachers and pilot these with students enrolled in courses in five universities or working in 'teaching schools' in different countries. The MOOC will also be delivered to thousands of student teachers from across Europe.
Finally, project partners will put in place a new ITE University-ICT industry Forum and work with a wider group of stakeholders online and in three Capacity Development Workshops in order to establish and sustain this as a permanent network under the independently funded Future Classroom Lab of European Schoolnet. The project course modules and MOOC will help bridge the ITE/CPD disconnect by providing concrete deliverables that will motivate ITE providers, companies and policy makers at national and regional level to actively participate in this project. European Schoolnet and its supporting ministries see this as a strategic next step in the development of the Future Classroom Lab.
ITELab is co-funded under the European Commission's Erasmus+ Programme from January 2017 to December 2019.
Download the ITELab Overview here.


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About Us
Darksiders II Avatar collection on Xbox Live
posted: 4/24/2012 1:24:00 PM
More On:
Darksiders II
You can dress your Xbox Live Avatar up anyway you want - anything from hipster to Commander Shepard (and even hipster Commander Shepard) is just a few clicks (and/or Microsoft points) away. And now you'll be able to add Death to the list of possible appearances. No, I don't mean how you looked like death after a 72 hour Red Bull bender. This Death is less vomit on your shirt and more four horsemen of the apocalypse trampling your face.
Starting today, you'll be able to purchase a full range of
Darksiders II
items. These items are the standard sets of armor, props, and clothing and will stab you in the wallet for anywhere from 80 to 400 (Microsoft) points of damage.
Unfortunately, there's nothing for PS3 users right now, but premium items are expected to come out later this year.
is giving away a free Xbox Live Avatar t-shit designed by game creator Joe Mad while supplies last. Visit
to learn how to get yours.
Like Darksiders on Facebook to Unlock Free Avatar T-shirt.
AGOURA HILLS, Calif. Apr 24, 2012
THQ Inc
. (NASDAQ: THQI) today launched a premium Avatar collection for Darksiders® II on the Xbox 360® video game and entertainment system from Microsoft.
The Xbox 360® Darksiders II Avatar Collection features a broad selection of different items to customize your Avatar's appearance ranging from full armor sets to animated props and clothing. Prices range from 80 to 400 Microsoft Points an item. A premium collection for the PlayStation®3 is expected to be released at a later date.
To celebrate the launch of the Darksiders II Avatar Collection THQ will be giving away a free Xbox LIVE Avatar t-shirt featuring a design by game creator Joe Mad while stocks last. To find out how to claim your Avatar t-shirt visit the Darksiders II Facebook page at
Jim Huntley, Vice President of Global Brand Marketing commented: "We are delighted to be able to celebrate the release of the Premium Avatar collection for Darksiders II by rewarding our community with a free Avatar T-shirt."
Fans of the game can still pre-order copies of the Darksiders® II Collector's Edition while supplies last. This ultimate package includes the Limited Edition version of the game as well as a life-sized replica Death Mask with display stand, a unique in-game Shadow of Death armor and scythe set with enhanced stats, a digital copy of the Darksiders II sound-track and a hard-cover Darksiders II art book. The Collector's Edition will be available in limited quantities as a pre-order item only and is anticipated to sell for around $99 USD.
Darksiders II follows the exploits of DEATH, one of the four horsemen of the Apocalypse, in an action-packed tale that runs parallel to the events in the original Darksiders game. This epic journey propels DEATH through various light and dark realms as he tries to redeem his brother WAR, the horseman blamed for prematurely starting the Apocalypse in Darksiders.
For full information on the Collector's Edition, Limited Edition and pre-order bonuses available for Darksiders II check out the Pre-order tab on
Darksiders II is scheduled to be available for console and PC in August 2012 with a WiiU™ version coming at a later date, for more information check
About Darksiders II
Awakened by the End of Days, Death, the most feared of the legendary Four Horsemen embarks on a quest to redeem his brother's name. Become the terrifying force which everything fears but nothing can escape.
The original Darksiders®, released in January 2010, received critical acclaim including the Best Fantasy Game 2010 award from IGN. Darksiders followed the story of WAR, wrongly accused of starting the apocalypse, on a quest to reclaim lost honor and take revenge on those who wronged him.
About THQ
THQ Inc
. (NASDAQ: THQI) is a leading worldwide developer and publisher of interactive entertainment software. The company develops its products for all popular game systems, personal computers and wireless devices. Headquartered in Los Angeles County, California, THQ sells product through its global network of offices located throughout North America, Europe and Asia Pacific. More information about THQ and its products may be found at
. THQ, Darksiders and their respective logos are trademarks and/or registered trademarks of THQ Inc.
Microsoft, Xbox, Xbox 360, Xbox LIVE, the Xbox logos, and the Xbox LIVE logo are either registered trademarks or trademarks of Microsoft Corporation in the U.S. and/or other countries.
"PlayStation" is a registered trademark of Sony Computer Entertainment Inc.
Nintendo trademarks and copyrights are properties of Nintendo.
All other trademarks are the property of their respective owners.
The statements contained in this press release that are not historical facts may be "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on current expectations, estimates and projections about the business of THQ Inc. and its subsidiaries (collectively referred to as "THQ"), including, but not limited to, expectations and projections related to the Darksiders II video game and are based upon management's current beliefs and certain assumptions made by management. Such forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such forward-looking statements, including, but not limited to, business, competitive, economic, legal, political and technological factors affecting our industry, operations, markets, products or pricing. Readers should carefully review the risk factors and the information that could materially affect THQ's financial results, described in other documents that THQ files from time to time with the Securities and Exchange Commission, including its Annual Report on Form 10-K for the fiscal period ended March 31, 2011 and subsequent Quarterly Reports on Form 10-Q, and particularly the discussion of trends and risk factors set forth therein. Unless otherwise required by law, THQ disclaims any obligation to update its view on any such risks or uncertainties or to revise or publicly release the results of any revision to these forward-looking statements. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press relea


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CMU to Host First Blow Pop Game
FAYETTE, MO — The Central Methodist men and women's basketball programs announced the first 'Blow Pop' game taking place Saturday. The Eagles will face off against MidAmerica Nazarene (Kan.), as they honor long time resident of Fayette and CMU alumnus Bill Holman.
Holman was a part of Mission Control during the historic moon landing of Apollo 11 in 1969. He was part of the team that pioneered development of the artificial heart leading to the invention of the Jarvik Heart.
The CMU athletic department will pass out Blow Pops during both games and honor special presentation to Martha Holman, Bill's wife, between the women's and men's basketball games. She will also be an honary coach for both of the games.
The Holmans, avid supporters of the programs, were known to pass out Blow Pops during basketball games. The Holman's also help establish three scholorships and have been genourous to the university.


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The display and use of drug information on this site is subject to express terms of use. By continuing to view the drug information, you agree to abide by such terms of use.
GENERIC NAME: ATAZANAVIR - ORAL (A-ta-ZAN-a-vir)
BRAND NAME(S): Reyataz
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life.Atazanavir belongs to a class of drugs known as protease inhibitors. It may be given with ritonavir, another protease inhibitor, to increase ("boost") the levels of atazanavir. This helps atazanavir work better.Atazanavir is not a cure for HIV infection. To decrease your risk of spreading HIV disease to others, do all of the following: (1) continue to take all HIV medications exactly as prescribed by your doctor, (2) always use an effective barrier method (latex or polyurethane condoms/dental dams) during all sexual activity, and (3) do not share personal items (such as needles/syringes, toothbrushes, and razors) that may have contacted blood or other body fluids. Consult your doctor or pharmacist for more details.OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This medication may also be used in combination with other HIV medications to reduce the risk of getting HIV infection after contact with the virus. Consult your doctor for more details.
HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking atazanavir and each time you get a refill. If you have any questions, ask your doctor or pharmacist.Take this medication by mouth as directed by your doctor, usually once daily with food. Do not open, crush, or chew the capsules. Swallow the capsules whole.The dosage is based on your medical condition, response to treatment, and other medications you may be taking. For children, the dosage is also based on weight. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). If you are directed to take ritonavir with this medication, take them both at the same time.If you are taking antacids or buffered forms of drugs (such as didanosine solution, didanosine enteric-coated capsules), take atazanavir at least 2 hours before or 1 hour after these medications.This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time each day.It is very important to continue taking this medication (and other HIV medications) exactly as prescribed by your doctor. Do not skip any doses. Do not take more or less of this drug than prescribed or stop taking it (or other HIV medicines) even for a short time unless directed to do so by your doctor. Doing so may cause the amount of virus to increase, make the infection more difficult to treat (resistant), or worsen side effects.
SIDE EFFECTS: Headache or nausea may occur. If either of these effects persists or worsens, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Some people may experience worsening of a previous medical condition (such as an old infection) as their immune systems improve, or develop new conditions because their immune systems have become overactive. This reaction may occur at any time (soon after starting HIV treatment or many months later). Tell your doctor right away if you have any serious side effects, including: unexplained weight loss, persistent muscle aches/weakness, joint pain, numbness/tingling of the hands/feet/arms/legs, severe tiredness, vision changes, severe/persistent headaches, signs of infection (such as fever, chills, trouble breathing, cough, non-healing skin sores), signs of an overactive thyroid (such as irritability, nervousness, heat intolerance, fast/pounding/irregular heartbeat, bulging eyes, unusual growth in the neck/thyroid known as a goiter), signs of a certain nerve problem known as Guillain-Barre Syndrome (such as difficulty breathing/swallowing/moving your eyes, drooping face, paralysis, slurred speech).Tell your doctor right away if you have any serious side effects, including: yellowing eyes/skin, increased thirst/urination, dizziness, lightheadedness, signs of a kidney stone (such as pain in side/back/abdomen, painful urination, blood in the urine).Changes in body fat may occur while you are taking this medication (such as increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of treatment with your doctor, as well as the possible use of exercise to reduce this side effect.Get medical help right away if you have any very serious side effects, including: signs of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating).Atazanavir can commonly cause a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Therefore, get medical help right away if you develop any rash.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
SLIDESHOWSee Slideshow
PRECAUTIONS: Before taking atazanavir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems (including hepatitis B or C infections), kidney problems (including kidney stones), heart problems (such as heart rhythm problems, irregular heartbeat, coronary artery disease, heart attack), diabetes, a certain bleeding problem (hemophilia).Atazanavir may increase the level of cholesterol and fats (triglycerides) in your blood. HIV infection can also cause this effect. This could increase your risk for heart problems such as a heart attack. Discuss the risks and benefits of treatment with your doctor and ways to lower your risk of heart disease. Tell your doctor if you have heart problems, if you smoke, or if you have other conditions that increase your risk of heart disease such as high blood pressure, diabetes, or high cholesterol/triglyceride levels.Before having surgery, tell your doctors or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Atazanavir should not be given to children younger than 3 months because of the risk of very serious side effects.During pregnancy, this medication should be used only when clearly needed. However, HIV medicines are now usually given to pregnant women with HIV. Treatment can decrease the risk of passing the HIV infection to your baby. Atazanavir may be part of that treatment. Discuss the risks and benefits with your doctor.It is unknown if atazanavir passes into breast milk. Because breast milk can transmit HIV, do not breast-feed.
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DRUG INTERACTIONS: See also How to Use section.Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Atazanavir interacts with many medications. One product that may interact with this drug is: indinavir.Other medications can affect the removal of atazanavir from your body, which may affect how atazanavir works. Examples include boceprevir, carbamazepine, etravirine, phenobarbital, phenytoin, nevirapine, rifamycins (such as rifampin), St. John's wort, voriconazole, among others.Atazanavir can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include some alpha blockers (such as alfuzosin), certain benzodiazepines (midazolam, triazolam), cisapride, ergot alkaloids (such as dihydroergotamine, ergotamine), fluticasone, irinotecan, lurasidone, pimozide, drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, vardenafil), certain "statin" cholesterol drugs (lovastatin, simvastatin), salmeterol, among others.Prescription and nonprescription drugs to treat heartburn, indigestion, or ulcers (including H2 blockers such as famotidine, proton pump inhibitors such as lansoprazole/omeprazole) reduce stomach acid and decrease the absorption of atazanavir. This may prevent atazanavir from working well. Ask your doctor or pharmacist how to use these medications safely.This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Talk to your doctor about additional or alternative reliable forms of birth control, and always use an effective barrier method (latex or polyurethane condoms/dental dams) during all sexual activity to decrease the risk of spreading HIV to others. Tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your hormonal birth control is not working well.
QUESTIONSee Answer
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, lightheadedness.
NOTES: Do not share this medication with others.Laboratory and/or medical tests (such as viral load, T-cell counts, liver tests, cholesterol/triglyceride levels, blood sugar levels) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
MISSED DOSE: It is important not to miss doses of this drug. If you miss a dose, take it as soon as you remember, unless it is less than 6 hours until the next dose. In that case, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised March 2013. Copyright(c) 2013 First Databank, Inc.
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.


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Mia Farrow cast doubt on Naomi Campbell's claim she didn't know the stone Liberian strongman Charles Taylor gave her was a diamond, testifying Monday at Taylor's war crimes trial that the supermodel boasted about the gem.
Farrow, who had attended a 1997 South African state dinner hosted by Nelson Mandela along with Campbell, music producer Quincy Jones and others, said she heard Campbell say that she had been given a "huge diamond" by Taylor.
"She said in the night she had been awakened by men knocking at her door that said they had been sent to her by Charles Taylor, and they had given her a very huge diamond," Farrow told the court in The Hague.
Later in the day, Campbell's former agent Carole White echoed Farrow's testimony.
She "was very excited and she told me he was going to give her some diamonds," White told the court.
Taylor is accused of several war crimes, but the Campbell testimony is aimed at proving he trafficked in "blood diamonds," which he traded for weapons to arm Sierra Leone rebels. Sierra Leone's bloody civil war lasted from 1992 until 2002 and left more than 100,000 dead. Taylor denies involvement in the diamond trade.
Farrow's testimony sharply contradicted Campbell's words from the stand last week, when she said she was given "dirty pebbles," which she had no idea were diamonds.
In court Monday, Farrow said she had seen Campbell join a group of guests at breakfast after the dinner, and that Campbell had recounted how two men had visited her room overnight, giving her a pouch of diamonds. Farrow said Campbell had then said she intended to give the diamond to the Nelson Mandela Children's Fund.
Taylor is accused of murder, rape, sexual enslavement and recruiting child soldiers.


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Religion has played a monumental role in shaping our world – as well as our institution . Its impact has been, and continues to be, indisputably powerful. And with its rich history and tradition, religion continues to spark important discussion, discovery and debate. Here at Lakeland, the religion program focuses on Christian theology, but Professor Karl Kuhn stresses that all religions – including Judaism, Islam, Buddhism, Hinduism, Shintoism and Taoism – are explored.
Growing spiritually, intellectually
"Our goal is not to indoctrinate students in a particular religious perspective, but to help them have a developed sense of the Christian theological tradition as a whole," says Kuhn, an ordained United Church of Christ minister who's been at Lakeland University since 1999 and authored three books. "And we want our students to engage in a broad set of religious perspectives."
Lakeland University began as a seminary of the church in 1862, a little more than a decade after German emigrants settled in Sheboygan. After Lakeland University expanded educationally, and the seminary moved to Minnesota, Lakeland University continued to embrace religion as a part of its overall identity and heritage.
Just as religion once helped shape what would become Lakeland University, Lakeland University remains committed to helping interested students shape their broad-based knowledge of religion.
Facts about Lakeland's religion program:
- To earn a major in religion from Lakeland University, a student must complete just 39 credits in the discipline. That relatively low number of required credits allows students to easily combine the religion major with other majors.
- Students who major in religion will critically analyze and discuss biblical texts and comprehend the foundation and culture of religions other than Christianity.
- The Mission House Center is an office on campus that provides opportunity for reflection and education. Twice a year, theological lectures are offered for students.
- There are no prerequisites or religion-based requirements for entering the religion program.
- Career placement for students with a religion major includes work in churches, homeless shelters, campus ministries, elderly care centers and church camps.


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By Dean Stattman Flex
Branched-chain amino acids (BCAAs) have repeatedly been proven to aid recovery and muscle protein synthesis, and leucine in particular appears to play a big role in these functions. One study from the University of Birmington in England found that when healthy men consumed a BCAA formula containing 3.5g of leucine before and after resistance training, they reported significantly less muscle soreness 48 and 72 hours afterward than the control group. In another study, published in The American Journal of Clinical Nutrition, researchers tested whether the amount of leucine in a BCAA supplement affected its impact on muscle protein synthesis after exercise. Sure enough, the group that was given a leucine-enriched dose experienced 33% greater muscle protein synthesis than the group who consumed the standard mix of essential amino acids. It looks like leucine may even be able to slow down the loss of muscle that occurs naturally with age, according to a study published in the Journal of Nutrition, which concluded that long-term BCAA supplementation containing excess leucine can overpower muscles' increasing resistance to protein synthesis over time. When it comes to recovery, you simply can't beat BCAAs, especially leucine-enriched formulas, which appear to deliver the best results.
REFERENCES: S.R. Jackman, et al., Med Sci Sports Exerc. 2010 May; 42(5):962-70.; S.M. Pasiakos, et al., Am J Clin Nutr. 2011 Sept; 94(3):809-18. E-pub 2011 Jul 20.; S. Fujita, et al., J Nutr. 2006 Jan; 136(1 Suppl):277S-80S
Source: http://www.flexonline.com/nutrition/…recover-faster


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Over 100 artists and activists, together with residents fearing displacement, consider utopian aspirations and plot alternative futures for the city of San Francisco. Includes work by Swoon, Barry...
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Most people outside of the art world view art as something that is foreign to their experiences and everyday lives. A People's Art History of the United States places art history squarely in...
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The photographic explorations of the life of a wanderer. This issue fills in the gaps of previous books, including wandering in a post-apocalyptic desert, squats and demonstrations across Europe,...
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The science is in: Global warming is for real. But what does it all really mean, and what can or should we do about it? This clear, fluid narrative by a leading scientist and educator takes a...
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Texas Schlitterbahn cited for death of lifeguard in wave generator
A federal safety agency has cited Enterprize Management Inc. and Schlitterbahn
Beach Resort Management LLC for six safety violations that led to the
death of a lifeguard and severe injuries to a maintenance worker this
The Occupational Safety and Health Administration
also levied fines of $96,000 against the two entities, doing business
as Schlitterbahn Beach Waterpark and Resort in South Padre Island.
The violations were issued for failing to protect workers from hazardous energy sources, according to press release from the U.S. Department of Labor.
OSHA launched its probe in March after the 20-year-old lifeguard and
maintenance supervisor entered a wave generation machine, which
inadvertently activated and caused them to be pinned between the gate
and the wall of the wave machine.
"By failing to properly train its workers and provide appropriate
lock-out and tag-out procedures for hazardous energy sources,
Schlitterbahn tragically exposed its workers to unnecessary risks," Michael Rivera, OSHA's Corpus Christi area director, stated in a press release.
"OSHA will not tolerate such neglect. It is the employer's
responsibility to find and fix workplace violations in an effort to
safeguard the health and safety of its workers," Rivera stated.
Enterprize and Schlitterbahn were cited for "failing to develop,
document and utilize procedures to control potentially hazardous energy
for equipment such as, but not limited to, the wave generation machine."
OSHA found that the entities failed to provide standard railings on
the open sides of all exposed stairways and stair platforms; failed to
conduct inspections of the energy control procedures; did not train
workers to recognize hazardous energy sources and procedures; and failed
to guard water pumps with rotating shafts and firmly secure an
electrical junction box to the wall.
A serious violation occurs when there is substantial probability that
death or serious physical harm could result from a hazard about which
the employer knew or should have known, the press release states.
The willful penalty totaled $70,000, while the serious penalties totaled $26,000.
Schlitterbahn has 15 business days to comply, request an informal
conference with OSHA's Corpus Christi area director, or contest the
findings before the independent Occupational Safety and Health Review Commission.
For more information or to file a complaint, call OSHA's toll-free
hotline at 800-321-OSHA (6742), or the agency's Corpus Christi office at
Source: https://www.chron.com/news/houston-texas/houston/article/Texas-Schlitterbahn-cited-for-death-of-lifeguard-4765295.php?cmpid=hpfc


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How to Sort Your Waste
Electronic waste
This item is electronic waste.
Take this item to a Peel Community Recycling Centre (CRC).
Additional information:
- Electronic waste is not collected at the curb.
- Dedicated loads of electronic waste are accepted at all CRCs free of charge.
- Protect your privacy. Always erase personal data from your electronics before donating or recycling them.
Other ways to dispose of this item:
- Some retailers in Ontario may accept electronic waste. Visit Recycle My Electronics for alternative drop-off locations.
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WASHINGTON (AP) — House Speaker John Boehner says the Supreme Court ruling upholding the individual insurance requirement at the heart of President Barack Obama's health care overhaul shows the need to repeal the law.
The Ohio Republican says in a statement that the law is hurting the economy by increasing health care costs and making it difficult for small businesses to hire.
He says the court's ruling demands repeal of the entire law.
Boehner say Americans want a common-sense approach to health care. He says Republicans are ready to work with a president who's willing to listen to the people and "will not repeat the mistakes that gave our country 'Obamacare.'"


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As I am new to the African continent, having recently relocated from the Netherlands to Johannesburg, what an exciting and inspirational couple of months it has been. Attending the World Economic Forum on Africa in Kigali, Rwanda has been both an absolute highlight, privilege and a great learning experience. Listening to political, economic and industry leaders about the challenges but more importantly, focusing on the opportunities that Africa presents for domestic economies, foreign investments and organisations establishing a new business across the continent has been a three day crash course!
The underlying tone at the WEF to grow local economies and improve the foreign investment landscape, has been strongly fuelled by the need for infrastructure, telecommunications, sustainable energy solutions, government support and transparency, and improved tax structures. The fast pace development of technology and improved accessibility to data has stimulated local young entrepreneurship and startups. I have noticed a strong emphasis from both government and private parties to support, collaborate and invest in those initiatives. When compared to past emerging markets such as Asia and India, Africa shows great potential to boost its economies, prosperity and business growth, through bypassing the traditional growth patterns. Challenging the status quo and the need for taking action is now. When speaking to various delegates, I have come to learn that the WEF on Africa is stimulating exactly that. Already tangible examples are presented of successful partnerships e.g. integrated infrastructure projects, that are positively impacting domestic projects, stimulating jobs and showing return on investments in country.
Whilst attending a breakfast session on Thursday morning, a particular quote was said by one of the panel members, that stuck in my mind and underpins the overall sentiment that resonates across Africa and globally – 'The fragility of perception of Africa'. With Africa's high diversity of people and cultures, history of country political instability and economic challenges, the perception of doing business in Africa balances a fragile line between positive and negative sentiment. Far too often the media will focus on the negatives instead of the positives. To change the sentiment and perception of Africa, we all need to shift the focus to the success stories and opportunities, because they are there!
The economic landscape is becoming more stable but remains fragile. The road to a more robust foundation is paved and gaining positive momentum. There is a need for focused leadership and there is a role for everyone to play. The time to act is now.
My key takeaway and positive message is that diversification across African countries is not a challenge but an opportunity to do things different, learn from the past, disrupt the traditional business landscape and to collaborate through new integrated partnerships. This differentiates Africa from other economies and will leap frog economic growth.
What a great continent, what an opportunity and what a great place to be!


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GREENSBORO, N.C. – Mitch Stevenson passed for three touchdowns and ran for two more in Southern Virginia University's 55-24 football win at Guilford College Saturday.
Senior linebacker Brett Kassel picked off a school-record three passes and recovered a fumble all by himself, which led to 21 of Southern Virginia's 24 points scored off Guilford miscues. The Knights (1-3) forced five interceptions and two Guilford (1-4) fumbles on the day.
Kassel's first interception came at a pivotal point of the game. The Knights regained a 14-10 lead late in the second quarter on the second of Jerry Washington's two short touchdown runs. On the ensuing possession, Kassel picked off Guilford's Zac Halbert at the Quakers' 34-yard line with 68 seconds remaining in the half. Three plays later, Stevenson scored on a 15-yard keeper, which helped Southern Virginia open a 20-10 lead just before halftime.
Moments after Stevenson's first of two third-quarter touchdown passes to Dewayne Beamon (5 rec., 114 yds., 2 TD), Kassel recovered a muffed kickoff return on Guilford's 40-yard line. Stevenson hit tight end Jeff Waldron with a 28-yard strike down to the Guilford 12 and two plays later scored on a keeper from seven yards out, which opened a 36-17 Southern Virginia advantage.
Stevenson, a sophomore, completed 25 of 36 passes for 460 yards and picked up 20 rushing yards on 15 carries. All three of his scoring passes came in the second half, two to Beamon, and a 36-yard fourth-quarter completion to Chris Harper, which was set up by Kassel's third interception of the afternoon.
Guilford held a 10-3 lead at the end of the first quarter on the first of two touchdown passes by freshman Steven Gregory and a 31-yard Owen Bridges field goal. Gregory, the Quakers' fourth starting quarterback this season, completed eight-of-21 passes for 115 yards in his college debut. He connected with sophomore B.J. McKeever from six yards out in the first quarter and threw a 37-yard scoring pass to junior Brandon Thompson in the third quarter. Halbert, Guilford's opening-day starting quarterback, saw his first action since a foot injury sidelined him in mid-September. He completed eight of 17 passes for 101 yards, but was picked off three times.
Guilford sophomore Lawrence Blake made a game-high eight receptions for 108 yards, his second contest with 100 or more receiving yards. Quakers' rookie Robert Smith made a game-high 13 tackles.
The Quakers visit league-rival Bridgewater College next Saturday (10/15) at 1:00 p.m.


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Michael Oxley should be on every advisor's radar. The former Republican congressman from Ohio who served as chairman of the House Financial Services Committee and co-authored the Sarbanes-Oxley Act of 2002 following the Enron scandal, registered as a lobbyist in February with the Financial Industry Regulatory Authority (FINRA) to help convince Congress that FINRA should be the self-regulatory organization (SRO) for advisors.
Oxley's registration form as a lobbyist for FINRA also states that current and anticipated issues he will focus on is the regulation of securities and markets as well as "harmonization of regulation of broker-dealers and investment advisers." The harmonization of advisor and broker rules is the contentious issue that is intertwined with the Securities and Exchange Commission's (SEC) attempts to write a rule to put brokers under the same fiduciary standard as advisors.
Oxley (left), who's now with the law firm Baker Hostetler in Washington after serving in Congress from 1981 to 2007, spoke with AdvisorOne's Washington Bureau Chief Melanie Waddell on Wednesday about his role in lobbying on behalf of FINRA, and whether he thinks the SEC will see a further funding boost.
Melanie Waddell: As you know, advisors are concerned about FINRA having oversight of them. Can you explain what your role will be as you lobby on behalf of FINRA?
Michael Oxley: Part of my role is educational. We hope to not only educate the members but the public in general about what was mandated in the [Dodd-Frank] Act and what comes next.
Waddell: When you say what was mandated in the Act, what are you referring to specifically?
Oxley: I think for the first time you really had direct mention of investment advisors [in Dodd-Frank] and how to go about their registration and regulation. So a lot of this is new [to those on Capitol Hill] and I think there is a lot of information we need to get out about the capabilities of FINRA … and whether the SEC will have the necessary resources to carry out [oversight of advisors]. We hope to have some allies in that area to help us deliver that message.
Waddell: Who would those allies be?
Oxley: I'm not at liberty to say right now.
Waddell: Are you actively going to Capitol Hill now to lobby on behalf of FINRA?
Oxley: We haven't yet. I haven't been up to the Hill on that issue.
Waddell: When do you think you will?
Oxley: We have a lot of organizational issues to take care of first.
Waddell: The Securities and Exchange Commission received a $74 million budget boost under the compromise continuing resolution (CR) that Congress passed a couple weeks ago. Do you see the need for the SEC to have more funds to deal with implementing Dodd-Frank?
Oxley: Yes, I think so, but I think that's as good as the SEC is going to get.
Waddell: You don't expect the SEC to receive more funding under the FY2012 budget?
Oxley: Not really. No.
Waddell: Advisors have fears about FINRA having oversight of them. How would you settle some of those fears?
Oxley: Part of it is education. Rick Ketchum [CEO of FINRA] and the folks at FINRA, I've worked with for years and I have great admiration for their abilities. The stark fact is that the alternatives that the SEC sent back to Congress [in the Section 914 study regarding the need for a self-regulatory organization (SRO) for advisors] as far as increasing the SEC's budget dramatically to include [more money to oversee] investment advisors, that's just not going to happen; the second option was to increase the [user] fees dramatically, and that's not going to happen in this Congress. So the alternative is an SRO and FINRA is the SRO to go to.
Waddell: FINRA would have to put an infrastructure in place to handle taking on oversight of more advisors, beyond the dually registered advisors it currently oversees.
Oxley: I think FINRA is head and shoulders above anybody else [in terms of an SRO option]. But obviously, part of the process moving forward is to present the case on how [FINRA] can handle that responsibility.
Waddell: How long do you think it would take for FINRA to put an infrastructure in place?
Oxley: You'd have to ask the folks at FINRA.
Waddell: How do you feel about how Dodd-Frank implementation is progressing, and Dodd-Frank in general?
I think it was a necessary response to an incredibly bad situation. Just like Sarbanes-Oxley, I would have written [Dodd-Frank] differently.


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The Lehigh Valley Association of Realtors released the March 2012 Market Update. " The statistics represented in the MLS Market Update are compiled monthly based on figures generated by The Lehigh Valley Association of Realtors MLS. Reproduction of any of this copywrited material is prohibited without prior written approval of the MLS."
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Some good news regarding the Park. Funds may become available to develop the Park further. The funds are part of an agreement made with West Devon regarding the house builders (Wainhomes) development. As part of their consent they are required to fund some open space projects.
More information is available on the North Tawton Park Facebook page.


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Welcome to the Apache Tomcat® 7.x software download page. This page provides download links for obtaining the latest version of Tomcat 7.0.x software, as well as links to the archives of older releases.
Tomcat 7 Software Downloads
Quick Navigation
Release Integrity
You must
verify the
integrity of the downloaded files. We provide OpenPGP signatures for every
release file. This signature should be matched against the
KEYS file
which contains the OpenPGP keys of Tomcat's Release Managers. We also
SHA-512 checksums for every release file. After you
download the file, you should calculate a checksum for your download, and
make sure it is the same as ours.
You are currently using http://mirrors.ocf.berkeley.edu/apache/. If you
encounter a problem with this mirror, please select another
mirror. If all mirrors are failing, there are backup
mirrors (at the end of the mirrors list) that should be
Please see the README file for packaging information. It explains what every distribution contains.
Binary Distributions
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ASSEMBLY HALL (ENTER by way of 239 Thompson Street)
Our Monday night Prayer & Meditation Circle offers a 45-minute-long chance for a small group of Judsonites to pray and focus their attention on the needs of the community within and outside Judson's walls. Some members of the circle pray, some meditate, and all are interested in creating a quiet vibration of generosity that just might ripple out into the world. To participate, simply show up at 239 Thompson Street at 7pm on any Monday.


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Latest News
Best hope to stop spill? Relief wells, but they're tricky
WASHINGTON — The last, best hope of stopping the oil that's gushing into the Gulf of Mexico is two "relief wells" that are being drilled, but they won't be finished until August.
While some scientists are skeptical that BP will be able to connect the relief wells to the original well bore on the first attempt — David Rensink, the incoming president of the American Association of Petroleum Geologists, has said the probability is "virtually nil" — others say that drilling a relief well is easier than drilling the primary well.
"A relief well is a standard operation when (companies) have blowouts," said Peter Clark, an associate professor of mineral engineering at the University of Alabama. "If they can't control (the flow) any other way, they drill a relief well."
Clark said he was optimistic that the relief wells would work, even though they must link up with a small pipe about 18,000 feet below sea level.
"Nothing that is being done to date is new technology," Clark said. "It's technology that has been used in other places, just not at this depth. They are not inventing anything. If they miss, they can back up and try again. It's not an all-or-nothing shot."
BP has every incentive to get it done as fast as possible, he said: "They are not going to cut any corners putting that relief well in. This is already costing them a fortune."
To improve its chances for success, BP is drilling two emergency wells at once, one 12,090 feet deep, the other 8,576 feet, but neither will be completed until August, more than 90 and perhaps as much as 120 days after the Deepwater Horizon rig exploded on April 20.
The relief wells' chances for success are enhanced because BP engineers already know the geology from having bored the first well.
BP "has a big advantage here because they have already drilled the original well, so they have a blueprint," said Stephen Sears, the chair of the Department of Petroleum Engineering at Louisiana State University. "They know the geology and they know the pressures. The big uncertainly is weather."
Hurricanes could delay things. Hurricane season began Tuesday, and BP would have to halt drilling and evacuate the rig that's overseeing the relief wells if a storm threatened. The National Oceanic and Atmospheric Administration recently projected that the Atlantic is likely to see eight to 14 hurricanes this season, with three of those likely to be major storms.
"We're going into hurricane season. Therefore, you need to have a plan for how you would suspend operations, if you had to, because of the weather," Coast Guard Adm. Thad Allen, who's overseeing the Gulf spill operation, said at a news conference Tuesday.
While the plan is to bring in a rig capable of withstanding "violent weather," Allen said, "nothing is fail-safe with hurricane season coming."
Relief wells have been used in the Gulf of Mexico before, but the precedent is discouraging. In 1979 the Ixtoc oil spill gushed for more than ninth months after a blowout; some 3 million barrels of oil are estimated to have been released before the leak was halted. The owner of the Ixtoc rig was Petroleos Mexicanos.
Last year an oil-rig explosion off the Australian coast required five attempts and 10 weeks before a relief well could plug it.
BP, feds could make millions from runaway well's oil
Obama orders firms to change drill plans that mimic BP's
What Congress was told Thursday about the oil spill


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The luxurious feel and performance of this terry velour golf towel, cleans clubs and keeps your hands dry on the course- not to mention the spirit you demonstrate while on the links. Makes a great gift for that golfer in the family.
Every order is custom printed and personalized to your needs direct from our production facility in Detroit, MI. Items are typically completed within 5 business days and then require additional shipping time to reach your location. Bulk orders of 12 or more items will take 7-10 business days for production.


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Twisted Pine's La Petite Saison
Twisted Pine Brewing Company debuted its summer seasonal, La Petite Saison, last week with an updated label. The beer itself, however, is the same recipe that won a bronze medal at the 2010 Colorado State Fair.
La Petite Saison is a light and effervescent Belgian-style ale with a pale gold body and a floral aroma with biscuity undertones. It's very easy drinking at 5.3 percent ABV, with a crisp and dry character that balances the interplay of citrus and spice with a hint of hop bitterness.
La Petite Saison is available on draft in the Ale House and in 22-ounce bottles.
Upslope's Belgian-Style Pale Ale
Upslope Brewing Co. also recently released one of its medal-winning beers, a Belgian-Style Pale Ale that won the Boulder brewery its first medal at the Great American Beer Festival.
"The beer … has always been a special one", says Matt Cutter, Upslope's founder, in a press release. "It was the 2009 Great American Beer Festival and our brewery was only 10 months old. We were awarded a bronze in the Pro-Am Category, which celebrates the bridging between home and production brewers. We were still essentially homebrewers ourselves."
The beer is packaged in striking white cans with light-gray lettering, and joins Foreign Style Stout in Upslope's limited-release series, a program made possible by recent brew house expansions.
Upslope also recently expanded its tap room hours to include Sundays. The new hours are 2–9 p.m. Tuesday–Thursday, 2–10 p.m. Friday and Saturday, and noon–7 p.m. Sunday.
Contact Tom Wilmes at firstname.lastname@example.com.


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Early Predictions for the Philadelphia Eagles' 2012 Final Roster
The majority of the Philadelphia Eagles' 53-man roster is already a given. However, there are a few lingering questions as far as how the numbers game goes as well as a few spots to be decided through competition.
When it comes time for the final cuts, coaches have difficult decisions to make. This is where the roster numbers game comes into play.
Should they go light at one position so they can keep a player at another position just because they really don't want to let him go? Is it more important to have depth at certain positions over others?
Teams usually have to cut players they like and hope they clear waivers so they can add them to their practice squad. The tricky part is guessing which guys have the best chance to slip through cracks in the waiver wire.
Under Andy Reid, the Eagles' roster breakdown has usually been like this (initially, after the final cuts):
Last year, the Eagles juggled the numbers a little bit and went light at tight end (2) and linebacker (6) so they could go heavier in the secondary (6 CBs, 5 safeties).
Will there be similar juggling this year? One thing is for sure, the coaches will definitely have some hard decisions to make once again. Here's my early stab at the initial 53-man roster along with a notable cut or two:
QB (3) Michael Vick, Mike Kafka, Nick Foles
RB (4) LeSean McCoy, Dion Lewis, Chris Polk, Bryce Brown
WR (6) DeSean Jackson, Jeremy Maclin, Jason Avant, Riley Cooper, Marvin McNutt, Chad Hall
TE (2) Brent Celek, Clay Harbor
OL (9) Demetress Bell, Evan Mathis, Jason Kelce, Danny Watkins, Todd Herremans, King
Dunlap, Dennis Kelly, Brandon Washington, Steve Vallos
DL (10) Trent Cole, Jason Babin, Vinny Curry, Brandon Graham, Phillip Hunt, Cullen Jenkins,
Fletcher Cox, Mike Patterson, Derek Landri, Antonio Dixon
LB (7) Demeco Ryans, Mychal Kendricks, Brian Rolle, Casey Matthews, Jamar Chaney,
Keenan Clayton, Monte Simmons
CB (6) Nnamdi Asomugha, Dominique Rodgers-Cromartie, Brandon Boykin, Curtis Marsh,
Brandon Hughes, Cliff Harris
S (3) Nate Allen, Kurt Coleman, Jaiquawn Jarrett
K (1) Alex Henery
P (1) Chas Henry
LS (1) Jon Dorenbos
Notable cuts: Joselio Hanson, Akeem Jordan, Moise Fokou, Stanley Havili, Darryl Tapp, Trent Edwards
Starting season on PUP or IR: Jason Peters and Colt Anderson
Reasoning for a few of the cuts:
What? No fullback? For my explanation on this, I'll defer to this article that I wrote a few weeks ago about the extinction of the fullback position on the Eagles. The quick summary is that the percentage of plays the Eagles used a fullback decreased by 50% from 2010 to 2011.
- In 2011, the Eagles used a fullback on only 16% of their offensive plays. Why devote a roster spot for that? Plus, the Colts didn't keep a fullback for most of Howard Mudd's career there due to his unique offensive blocking scheme.
Havili will likely be added to the practice squad again, just like last year.
Darryl Tapp is a player that becomes the victim of the numbers game. When you add up his salary, talent and potential (future value), it's just not enough to keep him over someone like Phillip Hunt.
The Eagles always keep 10 defensive linemen and usually the split is six ends and four tackles. I have them at five and five this year because Cox can and will play DE in some situations, thus making Tapp expendable.
Probably my biggest surprise is keeping Monte Simmons over Fokou and Jordan. This will be a tough call because Jordan has value on special teams and is an experienced backup.
However, Simmons showed promise in training camp last year after he signed as an undrafted free agent with the San Francisco 49ers. The 49ers are deep at linebacker so Simmons couldn't crack their roster and spent last year on their practice squad.
- Simmons actually played defensive end in college and finished with 21.5 sacks. He projected to outside linebacker in the NFL due to his size at 6′ 1″, 226 lbs. Here's a quick blurb on him from Inside the 49ers after watching him in some drills during training camp last year:
Two more players stood out in this drill – Will Tukuafu and Monte Simmons. Tukuafu gets a good push on whoever's blocking him – more of a push than Ricky Jean-François.
Monte Simmons was ferocious in this drill. He's the fastest outside linebacker around the edge, and he's also the most violent. Jim Tomsula gave him a lot of reps and was pleased with his work, giving him atta boys and pats on the butt.
Simmons is light for an outside linebacker – just 226 lbs. But he could fill a need as a situational pass rusher. He's an undrafted rookie from Kent State, and his jersey number is 47. He's someone to monitor throughout the preseason.
One thing is for sure, the Eagles could always use more "violent" players on defense!
Many players can look good in practice but never translate it to the filed (aka, the Na Brown syndrome). However, after looking a little closer at Simmons, I think he has a decent shot at making the roster.
Keeping Simmons over Jordan is might be a long shot, but Jordan is far from assured a spot on the roster.
Hanson is another guy I see as on the bubble, and I see that bubble bursting. The only thing he has going for him now is experience, but I believe UDFA Cliff Harris will show good enough potential in camp and preseason to warrant keeping him over Hanson.
Once training camp starts and we start to separate the men from the boys, the roster picture will work itself out. And, of course, injuries are always a huge factor in reshaping rosters as well.
But as for right now, do you see the roster turning out differently than the above? If so, how?