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OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Cutaneous T-cell lymphoma
Cutaneous T-cell lymphoma (CTCL) is a group of lymphoproliferative disorders characterized by localization of neoplastic T lymphocytes to the skin. Collectively, CTCL is classified as a type of non-Hodgkin lymphoma (NHL). The two most common types are mycosis fungoides and Sézary syndrome. Mycosis fungoides is the most common type of CTCL. The disease looks different in each patient, with skin symptoms that can appear as patches, plaques, or tumors. Patches are usually flat, possibly scaly, and look like a rash; plaques are thicker, raised, usually itchy lesions that are often mistaken for eczema, psoriasis, or dermatitis; and tumors are raised bumps, which may or may not ulcerate. Sezary syndrome is an advanced, variant form of mycosis fungoides, which is characterized by the presence of lymphoma cells in the blood. Extensive thin, red, itchy rashes usually cover over 80 percent of the body. Of all primary cutaneous lymphomas, 65% are of the T-cell type. The most common immunophenotype is CD4 positive. There is no common pathophysiology for these diseases, as the term cutaneous T-cell lymphoma encompasses a wide variety of disorders.
Treatment selection for CTCL depends on the extent of skin involvement, the type of skin lesion, and whether the cancer has spread to the lymph nodes or other internal organs. For mycosis fungoides, treatment is either directed at the skin or the entire body (systemic). Because Sézary syndrome is chronic and systemic (affecting the entire body), it is usually not treated with skin-directed therapies alone. Treatments may be prescribed alone or in combination to achieve the best long-term benefit. Many patients live normal lives while they treat their disease, and some are able to remain in remission for long periods of time. Skin-directed therapies are useful for patch and limited plaque disease and include topical treatments such as corticosteroids, retinoids, or imiquimod (which activates immune cells), topical chemotherapy, local radiation, methotrexate, photopheresis, ultraviolet light (phototherapy).
Many treatments at various stages of drug development are currently being tested in clinical trials and for various stages of CTCL, including everolimus (Afinitor), lenalidomide (Revlimid), brentuximab vedotin (Adcetris), panobinostat, forodesine, APO866, KW0761, and others. It is critical to remember that today's scientific research is continuously evolving. Treatment options may change as new treatments are discovered and current treatments are improved. Therefore, it is important that patients check with LRF or with their physician for any treatment updates that may have recently emerged.
The annual incidence of CTCL is approximately 0.5 per 100,000, having a higher prevalence among men than women (male-to-female ratio of 1.6 : 1–2.0 : 1) and typically seen in adults with a median age of 55–60 years at diagnosis.

subset: commoncrawl


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The Alexor is a DSC Wireless Alarm, model PC9155, which is a huge step up from the DSC 9047. Like all DSC products, this new system has continuously been pushed back a few times, but I have received word that it is hitting distribution centers as we speak. The DSC Alexor is easy to setup and program. The programming is very identical to the current DSC Power Series alarms.
What sets the Alexor apart from the 9047 is the options you have to mount and place the individual components. The main console, brain, of the system is able to be placed out of sight, such as a closet. The Alexor is bi-directional which allows for a wireless siren and completely wireless keypads. The keypad is much like the fully programmable aplha 5500 keypads. Since the system is bi-directional that means signals can be sent to and from the brain, which will also allow the WT4989 key fob to actually show the status of your alarm (armed, disarmed, troubles, etc..) with its LCD Graphic display. This system will be more reliable and much harder for an intruder to damage the system. Many other alarm systems are self contained which means if an intruder breaks in, they can simply rip a unit off the wall and the keypad, siren, and power can all be affected. The Alexor's keypad, siren, and power are all separated from each other, which keeps the alarm functioning properly if someone wants to rip the keypad off the wall or even take down the siren. By far, The DSC Alexor PC9155 will be one of the most reliable, if not the most reliable, wireless alarm system on the market.


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Books, Movies, Music
JCPL Catalog
Reading programs and Book Groups
Kids & Teens
Kids Zone
Teens Only
For Parents and Teachers
Student Portal
Main Content
You'll Love Checking Out These New Fiction Titles @ JCPL!
It's February; love is in the air.
Scrolling through some Internet sites, I came across this definition of love: "Love is a wildly misunderstood, although highly desirable, malfunction of the heart, which weakens the brain, causes the eyes to sparkle, cheeks to glow, blood pressure to rise and the lips to pucker."
This quote, written by an unknown author, is the very definition of the "L" word in most households, and also in mine, unless ham is the chosen meal for that particular day.
To me, cooking a ham is a straightforward venture; glaze it, bake it and then eat it. To my husband, it is an art, to be perfected by mixing a hodgepodge of ingredients, glazing the outside of the meat with much ado, and baking, checking, baking, checking, etc, in which case, I abandon the ham, steer clear of the kitchen entirely, and go find a good book to read.
Lucky for me I always check out stacks of the new fiction titles at my local branch of JCPL! Read on!
As I began reading "A Winter Dream" by Richard Paul Evans, I got involved in the family drama surrounding Joseph and his many brothers as they helped their father run the family advertising company. Joseph, one of the younger of the tribe, was a talented ad writer who saved the business by coming up with a winning ad campaign for a large bank, while his brothers seethed in a jealous rage over his success and the fact that he had found such favor in the eyes of their father. Their rage with him was, in fact, so intense that they conspired to exile him from the business, succeeding in their quest only to find themselves in a financial dilemma years later that brought them full circle and face to face, once again with their long lost brother. So immersed in the story, I waited until I finished it to read the blurb on the cover, only to confirm what I had suspected; that the story was loosely based on "Joseph and the Coat of Many Colors." A great holiday story, told by a great storyteller!
After a tragic accident shattered her dreams and took away her one and only true love, Rory Mackenzie vowed never to revisit her Ransom, California hometown. Her past, however, comes back to haunt Rory when a shocking murder occurs in Ransom, and she is drawn into the courtroom drama as juror number seven, dredging up disturbing images from her past in the process in "Ransom River" by Meg Gardiner.
On a winter excursion to her hometown in Colleton County, Judge Deborah Knott and her husband, Dwight Bryant, are enjoying reconnecting with old friends and family members. On their list of those to visit during their stay is Mrs. Lattimore, a woman in failing health whose only wish is to make amends with her family, and in particular, her daughter, Anne. A dinner party at Mrs. Lattimore's Victorian home includes her long lost nephew, ornithologist, Martin Crawford. Although charming, something about Martin strikes a familiar chord in Anne, and when a string of suspicious murders occurs, Anne's reservations about Martin deepen and long-buried family secrets emerge in "The Buzzard Table" by Margaret Maron.
Former small town football star-turned-pastor, Walker "Bear" Wells, has seen his share of emotional and spiritual dilemmas as he serves his small Texas community with as much faith as a pastor can muster. He's dealt with problems in both his congregation and his own family, but something that has never been part of his daily routine is murder, and now that it is, Bear finds himself tangled up in an investigation that would be better left to the pros. The only problem is that this murder has become personal, because the murdered man is the father of his rebellious daughter's boyfriend, and, as you may have guessed, the boyfriend is the prime suspect in "Faithful Unto Death" a Sugar Land Mystery by Stephanie Jaye Evans.
Ham, like love, can be wildly misunderstood if left in the wrong hands, in which case, I'll pass on the weak brain, sparkling eyes, high blood pressure, and puckered lips of ham AND love by checking out a good book from my friends at JCPL! Happy February, everyone!


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Entitlements: Time running out on Social Security, Medicare fixes
WASHINGTON — Social Security and Medicare long have been considered the nation's fiscal time bombs, and the ticking is getting louder. But presidential candidates Barack Obama and John McCain have no comprehensive plans to overhaul the systems, and are campaigning almost as if they don't notice them.
Medicare faces insolvency by 2019. Social Security is projected to be spending more than it's collecting in taxes by 2017.
Yet both Obama and McCain offer only minor fixes — and few specifics even about the modest ideas they do float.
Bigger, bolder, more sweeping approaches are needed, and fast, say the experts.
"They're not preparing the country for sacrifice," said Robert Bixby, the executive director of the Concord Coalition, a nonpartisan budget watchdog group.
The candidates insist that they're aware of the problem's gravity. At Tuesday's debate, they were asked which of three big problems would be their highest priority: health care, energy or reform of the entitlement programs Social Security, Medicare and Medicaid.
McCain said he'd work on all three at once, while Obama cited energy first, health care second — and education third. He didn't mention entitlement reform.
Time works against both candidates.
Beginning in 2011, the first wave of baby boomers — Americans born between 1946 and 1964 — will reach official retirement age. From that point forward, the federal government's finances will be strained, as more and more Americans retire expecting a shrinking number of active workers to pay their promised health and pension benefits.
To put it more starkly: Medicare's trustees project the hospital insurance fund will become insolvent in about 10 years, as its expenditures grow at a 7.4 percent annual rate. The government, the trustees said, will need $342 billion to cover insurance costs during that period.
Social Security is in better shape, but has its own daunting challenges. While it isn't projected to exhaust its resources until 2041, its tax revenue is expected to fall behind outlays beginning in 2017, the trustees said.
The next president will be under pressure to stabilize funding for the two programs.
"The longer action on reforming health care and Social Security is delayed, the more painful and difficult the choices will become," said a Government Accountability Office study in June. "The federal government faces increasing pressures, yet a shrinking window of opportunity for phasing in adjustments."
Medicare, the report said, "represents a much larger, faster-growing and more immediate problem than Social Security."
A series of factors are driving up Medicare costs. According to the GAO and the trustees, medical technology is often overused; the health-care market doesn't operate on a supply-and-demand basis as people often don't shop for the lowest price; and chronic health problems — such as obesity or substance abuse — require expensive, lengthy treatment.
McCain's plans for Medicare are part of his overall health care initiative. He'd offer tax credits of up to $2,500 to individuals and $5,000 to families to help offset the cost of health insurance. Premiums for employer-sponsored health care average $12,680 this year, and employees contribute $3,354, according to a Kaiser Family Foundation survey.
McCain said he'd pay for the tax credits with unspecified cuts in Medicare and Medicaid, the state-federal health program for the poor and disabled. The Urban Institute-Brookings Institution Tax Policy Center estimates that McCain's proposed tax cuts would cost the Treasury $1.3 trillion over 10 years. The Arizona senator hasn't detailed how he'd cut that much from Medicare and Medicaid.
"We should avoid across-the-board cuts or other cuts to Medicare and Medicaid that could reduce benefits for the millions of older Americans, low-income families and people with disabilities who rely on these critical health and long-term care benefits," said Drew Nannis, a spokesman for AARP, the powerful lobby for seniors.
McCain vows to "reform the payment systems" in the two programs "to compensate providers for diagnosis, prevention and care coordination." He'd give states more flexibility to experiment in managing Medicaid costs, and make it easier for consumers to get data about costs and physician quality.
McCain would also create a commission to recommend changes.
Obama's plans are similarly vague.
He pledges to "reduce waste in the Medicare system, including eliminating subsidies to the private insurance Medicare Advantage program, and tackle fundamental health care reform to improve the quality and efficiency of our healthcare system."
Obama also backs closing the "doughnut hole" in the Medicare prescription drug program. The standard drug benefit includes a $275 deductible and 25 percent coinsurance up to the first $2,510 of prescription costs. Then beneficiaries get no coverage for their next $3,216 in costs. After that, they pay 5 percent of their drug costs.
Analysts find both plans too vague and to small to address Medicare's larger trouble.
"Neither Obama nor McCain has outlined in any great detail any kind of structure change in Medicare," said Robert Moffit, director of the Heritage Foundation Center for Health Policy Studies.
"The only thing McCain does is talk about the importance of pay-for-performance, and that will get some savings, but neither he nor Obama has articulated any kind of detailed comprehensive change."
McCain opposes the generous but expensive Medicare prescription drug program. He favors making the Part D drug benefits available only to the needy. AARP disagrees.
"Some specific proposals, such as those to income-relate Part D premiums, do nothing to address the broader problem of rising health care costs. Increasing premiums simply shifts additional costs onto people in Medicare," said AARP's Nannis. "Instead, our priority should be to bring down prescription drug and health care costs throughout the health care system."
The differences between the candidates are starker on Social Security, yet solutions are regarded as somewhat easier to implement.
David Walker, former Comptroller General and now president of the Peterson Foundation, a nonpartisan budget research group, called a fix "easy." Former Federal Reserve Board Vice Chairman Alice Rivlin sees consensus forming around several solutions, notably raising the retirement age and increasing the income limit subject to the Social Security wage tax. Currently, Social Security taxes are collected on only the first $102,000 of income.
The candidates, though, aren't talking about those steps.
McCain in the past has been sympathetic to private savings accounts, saying he "supports supplementing the current Social Security system with personal accounts — but not as a substitute for addressing benefit promises that cannot be kept."
With the recent stock-market swoon, personal accounts invested in stocks and bonds are a hard sell.
McCain has ruled out any new Social Security taxes, while Obama has expressed interest in boosting the cap by 2 percentage points to 4 percentage points for workers earning more than $250,000. The current 12.4 percent payroll tax that goes into Social Security is split between employer and employee.
The usual Washington way of making such unpopular changes is to have a bipartisan commission make recommendations, a method used successfully in 1983. The result raised Social Security taxes and trimmed benefits, and the system's solvency was significantly strengthened.
Many analysts believe that a commission is a viable idea. "A lot of members of Congress are ready to work together on this, but they have to be assured no one is going to try to double cross the other person," said Maya MacGuineas, president of the Committee for a Responsible Federal Budget.
But Brian Riedl, senior policy analyst at Washington's Heritage Foundation, a conservative research group, was less optimistic.
"There's a bias in Congress against creating commissions. Members feel they're usurping their authority," Riedl said.
To ask a question about this story or any economic question, go to McClatchy's economy Q&A
Many doubt that McCain's health plan would help uninsured
Complete McClatchy election coverage
Elizabeth Edwards calls McCain plan 'dangerous'"


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Mercedes-Benz C63 AMG Wheel Bearing Replacement Cost
Know what price you should pay to get your vehicle fixed.
What is a wheel bearing?
A wheel bearing is a set of steel ball bearings that are held together by a metal ring that allows the wheels of a car to spin with as little friction as possible.
Each wheel on your vehicle has its own wheel bearing, and problems could start with any one of them.
What are the symptoms of a bad wheel bearing?
Some of the more common signs of wheel bearing problems include:
- Groaning, rumbling or grinding noises coming from the wheels or tires — these sounds may also get louder when you make a turn.
- The car handles more loosely.
- Vibrations and wobbling through the steering wheel.
- The car pulls to one side as you drive. This may occur at random.
- The tires wear unevenly.
If the above symptoms are ignored, more serious consequences can happen:
- One of the wheels starts smoking.
- A wheel comes off the vehicle.
How does a wheel bearing work?
A wheel bearing is part of the front and rear wheel hubs. In the front, the hub connects the wheel to the suspension's steering knuckle. The wheel connects to the hub, and the hub spins smoothly inside the wheel bearing. This allows the weight of the vehicle to rest on the hub as it spins while maintaining as little surface contact as possible.
The wheel bearing is lubricated with grease in order to further reduce friction. Most vehicles feature sealed wheel bearings that encapsulate the ball bearings and the lubricant.
Can I drive with a bad wheel bearing?
Yes, but not for long. As the wear increases, so do the chances of damage occurring to other parts of the suspension.
If you suspect that a wheel bearing is beginning to wear, have a technician evaluate the problem as soon as possible. A vehicle with a significantly worn wheel bearing shouldn't be driven. If the wheel bearing fails completely, it's possible for the wheel to come off the vehicle and cause a wreck.
How often do wheel bearings need servicing or replacement?
Most vehicles have sealed bearings that do not require maintenance. Sealed bearings can last 100,000 miles or more, and will need to be replaced once they go bad.
Vehicles with traditional, tapered wheel bearings should have them serviced every 25,000 to 30,000 miles — replacement may not be necessary as long as they're maintained.
How are wheel bearings replaced?
To replace a wheel bearing, a technician will need put the car on a lift, remove the wheel and tire, and remove the brake caliper and rotor.
On some vehicles, the wheel hub and bearing are simply unbolted from the steering knuckle and can replaced as a unit. On other vehicles, though, the hub and bearing are pressed together into the knuckle and need to be removed with special tools. In these cases, a hydraulic press must be used to insert the new hub.
Wheel Bearing Replacement Cost Estimates
The average cost for a Wheel Bearing Replacement is between $582 and $843 but can vary from car to car.
Can I replace the wheel bearing myself?
Some vehicles with sealed front wheel bearings can be serviced at home. If the wheel hub and bearing are simply bolted to the knuckle and can be replaced as a unit, an intermediate DIYer with experience removing brake or suspension parts can do it.
But many cars require that a technician remove hubs and bearings that are pressed into the knuckle. These components are difficult to disassemble, and reassembly requires a hydraulic press. In such cases, wheel bearing replacement is best left to a professional technician.
How are wheel bearings diagnosed?
To diagnose whether a wheel bearing is going bad, a technician will typically take the vehicle for a test drive to verify where the sound is coming from and determine which wheel bearing is the culprit.
In the shop, the technician might lift the vehicle, rotate the wheel, and listen for sounds from the wheel hub. The technician will also test the wheel for excessive play by holding the tire on each side and rocking it back and forth. If there is play in the wheel and the steering and other suspension components are in good condition, the bearing has likely worn out.
What to look out for with wheel bearing issues
The front wheel bearing is an essential component of the vehicle suspension. As a wheel bearing wears out, more friction is created — and more damage occurs. On most vehicles, the wheel bearing requires special equipment to be serviced. If a bearing is installed improperly, it may fail early.
- Repair shops in Sterling, VA
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Paula Whitsell
E-Mail : firstname.lastname@example.com
Whether you are looking to buy or sell your property, you have come to the right place! With more than 20 years of experience in Finance and Real Estate I am skilled at negotiating the best deal for you.
Give me a call or email me!
For Real Estate news, check out our blog at www.REALESTATESCOOP.net!


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Wednesday, May 21, 2008
Big News from Saskatchewan and Orchard
Media release
Wednesday, May 21, 2008
David Orchard to run for the Liberal nomination in Desnethé-Missinippi-Churchill River
"Following an extensive period of consultation across the riding, I have decided to put my name forward as a candidate for the Liberal Party nomination in the northern Saskatchewan riding of Desnethé-Missinippi-Churchill River.
As part of the Liberal team, I will offer my energy and experience to work for an alternative vision for the riding and the country to that put forward by Stephen Harper's government. If selected, I intend to speak for Metis, First Nations and non-aboriginal alike. Mine will be a fighting voice for. everyone — the Meadow Lake farmer, the daycare worker in Sandy Bay, the student in Pinehouse, the trappers in Cumberland House, or the fishermen and women in Wollaston Lake. It is my hope to also be a voice for understanding across the cultural and racial divide in this far-flung riding, which covers over half of Saskatchewan.
I pledge my strengths to the battle for justice and fair play for a region in Canada that has not seen enough of either.
I am a fourth generation farmer who knows agricultural issues in my bones. As a teenager I drove a tractor in farm protests. In 1975, our farm made the transition to 100% organic production. In 1995, I ripped up the Crow benefit cheque for $15,000 for my farm at a press conference, because I believed that the Crow rate, guaranteed to farmers in perpetuity, was not for sale.
I have spent thousand of hours in the battle for First Nations and Metis rights. In the 1980s, I was part of the effort (successful) to save the historic bullet scarred boards on the front of the rectory at Batoche. In the 1990s, I stood with the Elders and protesters at Canoe Lake, was arrested and jailed with them, in the battle for environmental protection and for a fair return to First Nations for their forest resources.
Throughout my adult life I have worked to protect our country's sovereignty and the environment upon which we all depend for our survival.
In the weeks ahead, I will continue to travel from farm to farm, town to town and First Nation to First Nation across the north to speak, to learn and to listen.
I will ask for support from across the riding and in turn will continue to give my all, whether on the national stage or on one in Pelican Narrows or Ile-a-La-Crosse, for a better, stronger, fairer Canada for all of its citizens, regardless of race, colour, occupation or background."
8 comments:
- WesternGrit said...
- May 21, 2008, 3:01:00 PM
- James Curran said...
And exciting!
- May 21, 2008, 3:14:00 PM
- Lizt. said...
I like Orchard, although some Libral bloggers, cannot stand him. He is better than the clueless on the Con. side. He could do a great deal for the country, if given a chance.
- May 21, 2008, 11:20:00 PM
- James Curran said...
Those bloggers should get over it. The status quo of Liberals in Sask hasn't worked in decades. Time for something completely different.
- May 21, 2008, 11:31:00 PM
- Jon said...
I think you meant to say "The Status Quo of Liberals... hasn't worked in decades." No need to specify Saskatchewan.
- May 22, 2008, 11:04:00 AM
- James Curran said...
NO Jon. Sask has been underachieving for the Liberal Party for decades. We should be carrying more than one seat in that province. Never mind the total destruction of the provincial Liberals in the last election.
- May 22, 2008, 11:17:00 AM
- lance said...
Uh huh James. The Libs are decimated here with a regularity that makes Ex-Lax jealous and you're blaming the people.
Here's a hint, it isn't the messenger.
Mr. Orchard has nothing to do with a "new" Liberal party in Saskatchewan.
He simply takes his place after Mr. Goodale and Mr. Merchant. "New" would be participating in the Liberal Renewal Workshop on the 31st.
But that's a radical thought, far too radical for established Liberals.
- May 22, 2008, 12:12:00 PM
- James Curran said...
Really. Like all the workshops I attended prior to our last convention? You know, the ones where we were the BIG TENT party and that's why guys like Rae and Dosanjh fit well with us.
Party renewal means including those that may have a different view of the world we live in. That includes David Orchard.
- May 22, 2008, 12:30:00 PM


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Hy End - Bruckner, Brahms, & Bang-Bang Lang Lang Liszt, by Hy Sarick
"Here, the showiest of pianists encounters the showiest of composers, and produces a stunning disc of great passion and virtuosity. Lang has been a devotee of Liszt's work from the age of 2 (!!), since his first encounter with Classical music - Tom & Jerry's version of the Hungarian Rhapsody No. 2.…"


text:
Re: suggestion... how about introducing ourselves??
Posted: Tue Jul 11, 2017 9:24 pm
wagolynn wrote:Hi Steve1960,
This can only ever be a personal choice (bearing in mind the from the medics).
If I had to make the choice, I would go for the reconstruction, risks, and all, my logic being, if it works a transplant my not be necessary with all the baggage that brings. All the tissue involved will be yours.
Best wishes.
I think you are probably correct, I am 75% convinced to have the reconstruction, I will be in UCH on Monday for the first clinic after my consultant referred me.


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A practical experiment demonstrating the importance of impedance matching in a waveguide system
This article has been written by Konstantinos Giannopoulos. He has graduated from the University of Portsmouth in UK. He has a BSc degree in Computer Technology and an MSc degree in Communication Networks Planning and Management. For more information you could visit his site here .
The article demonstrates a practical experiment to show the importance of impedance matching in a waveguide microwave system. Matching is always an issue not only in microwaves but also in audio and not only in waveguide systems but also in coaxial. Impedance mismatching introduces standing waves that cause power losses, reduction in power handling capability and frequency instability. Thus, it is very important to match a system and this is demonstrated by this experiment.
The components that were used for the experiment were:
The circuit setup can be shown in the next photo. The gunn oscillator produces an X-Band carrier signal. The wave meter next to it measures the frequency of this signal by allowing it to pass through it to the detector, only when it resonates to the signal frequency. With the current setup the wave meter resonates at about 9.113GHz. Next to the meter the waveguide filter/attenuator is connected to allow for the settings to be done and finally, the detector is used to detect the carrier and send an amount of current to the current meter.
Before switching on the gunn oscillator some final checks were made. The current meter polarity had to be done negative because the AEI CS9-B mixer diode used, has negative polarity. The attenuator of the meter was calibrated to 5Kohm to allow a greater current to be read and to extend the scale of the microampere meter.
The first try was without the filter. The meter read a current of 45 microamperes max (including the 5Kohm attenuator). Then the filter was added with the tuning screws not injected into the waveguide (un-tuned). The current reading had also a value of 45 microamperes.
At this time, the load is not fully matched to the source and there are no tuning screws injected into the system, except of the screw of the gunn oscillator to set it to the right frequency. The crystal holder has a ramp inside that acts as a transformer for the high frequencies for better matching but this is not enough. By making several adjustments to the screws of the filter, a meter current reading of more than 100 microamperes can be achieved. That is because the load has been fully matched now to the source by using the matching screws to vary the capacitance inside the waveguide. The standing waves have been minimized and more power reaches the detector.
The results of the experiment can be summarized in the next table.
Current meter reading
Operating without filter or un-tuned filter
< 45 microamperes (5Kohm attenuated)
Operating with tuned filter
>100 microamperes (5Kohm attenuated)


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27 July 2011 at 2.42pm | Comment on this article
The Mariinksy Ballet is now in residence, and there is an air of glorious Russian glamour about the place. So it's timely to pay tribute to Russian classical ballet, St Petersburg, and the choreography double act of Petipa and Ivanov. Where would we be without them?
We've ventured into the lesser-travelled byways of www.roh.org.uk and hooked out some history for dedicated fans of Russian dance.
Marius Petipa
The colossus of 19th-century ballet
- Clement Crisp
Petipa's ballets fused French sophistication, Italian brio and Russian majesty into the form that we now recognise as 'classical ballet' (as distinct from romantic or modern ballet). As such, Petipa's phenomenal influence has touched almost every ballet company and choreographer since. Even his predecessors are indebted to him: some earlier works such as Giselle and Coppélia have survived only through Petipa's restagings of them
'Classical ballet' as a technique derives from a set of codified principles – the placement of the feet, the iconic steps and stances, the clarity and proportion of the positions originally devised in the highly elaborate social world of the French courts. Petipa developed this style to virtuoso levels, displaying the brilliance of his dancers as if to raise a mirror to the grandeur of his Russian imperial audience. The ballerinas' short, stiffened tutus showed off their fancy footwork and perfect alignment. Their 'steely' pointe work, sharper and harder than the softer romantic style, emphasised precision, line and balance.
But classical ballet is not just technique, it is also theatre. In this respect, too, Petipa both played to his aristocratic imperial audience and led them to new heights. His first major success was The Pharaoh's Daughter (1862), an elaborate, evening-length epic with a cast of 400 dancers that established the fashion for the ballet à grand spectacle. [Read on in the Discover section]
Lev Ivanov
No artist ever made a stronger claim to posterity's respect for creating half a masterpiece
- Roland John Wiley
The 19th-century Russian choreographer Lev Ivanovich Ivanov is something of an enigma. He is the man responsible for two of the world's best loved ballets: Swan Lake and The Nutcracker, yet he seems to have left so faint a mark in the history books that he has been largely overlooked until relatively recently. He choreographed nearly 20 different ballets, some by himself and some in collaboration with Marius Petipa, however he did not always receive full dues for his work as Petipa was often credited in the programme. [Read on in the Discover section.]


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Start by carefully considering what you think you want. Then weigh your wish list against what you'll probably pay to fulfill it. Identifying goals and thinking through available options will force some decisions—and also help you set a budget cap.
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U.S. FDA Grants Priority Review to Boehringer Ingelheim's Afatinib NDA for EGFR Mutation-Positive Advanced NSCLC
For U.S. Media Only
Ridgefield, CT, January 15, 2013 – Boehringer Ingelheim Pharmaceuticals Inc. (BIPI) today announced that the New Drug Application (NDA) for its investigational oncology compound afatinib has been accepted for filing and granted Priority Review by the U.S. Food and Drug Administration (FDA). The application for afatinib is currently under review for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with an epidermal growth factor receptor (EGFR) mutation as detected by an FDA-approved test. Under the Prescription Drug User Fee Act (PDUFA), the FDA goal for reviewing a drug with Priority Review status is six months from the NDA filing acceptance date.1 The FDA target action date for afatinib will be in the third quarter of 2013.
Recently, afatinib was also granted orphan drug designation – a status given to a product intended for the treatment of a rare disease or condition.2 In the United States, orphan drug status provides for seven years of market exclusivity for the orphan drug indication following FDA approval.2 Currently there are no therapies specifically approved by the FDA for patients with locally advanced or metastatic NSCLC with an EGFR mutation.
"The NDA filing of afatinib represents Boehringer Ingelheim's commitment to addressing the significant need that exists for patients with EGFR mutation-positive advanced non-small cell lung cancer," said Sabine Luik, M.D., senior vice president, Medicine & Regulatory Affairs, U.S. Regional Medical Director, Boehringer Ingelheim Pharmaceuticals, Inc. "We are pleased that the FDA has accepted the afatinib application under Priority Review and look forward to working with the agency in the coming months."
The NDA submission for afatinib is supported by Boehringer Ingelheim's comprehensive LUX-Lung clinical trial program, including LUX-Lung 3, the largest Phase III trial conducted to date in first-line EGFR mutation-positive, locally advanced or metastatic NSCLC patients.
"This is an exciting milestone for Boehringer Ingelheim, as this marks our first oncology compound to be submitted for FDA review in the United States," said Kevin Lokay, vice president and business unit head, Oncology, Boehringer Ingelheim Pharmaceuticals, Inc. "Based on the acceptance of the afatinib application, along with our developing oncology pipeline, we are moving forward with our plans to establish a world-class oncology commercial organization."
To facilitate the rapid identification of EGFR mutations, Boehringer Ingelheim is partnering with QIAGEN – a leading global provider of sample and assay technologies – to develop a companion diagnostic for afatinib.
About Afatinib
Afatinib is an investigational, oral, once-daily irreversible ErbB Family Blocker that specifically inhibits epidermal growth factor receptor (EGFR or ErbB1), human epidermal receptor 2 (HER2 or ErbB2) and ErbB4.3 It is currently in Phase III clinical development in advanced NSCLC, head and neck and breast cancer. Afatinib is not approved by the FDA; its safety and efficacy have not been established.
In Europe, Boehringer Ingelheim announced submission of a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) seeking approval of afatinib as a treatment for patients with EGFR (ErbB1) mutation-positive NSCLC in September 2012.
About the Companion Diagnostic
Boehringer Ingelheim and QIAGEN are partnering on a companion diagnostic for afatinib. The therascreen® EGFR RGQ PCR kit is being developed by QIAGEN to identify patients with EGFR mutation-positive tumors.
EGFR is a specific protein found on the surface of cells. In some people, genetic mutations involving EGFR lead to its constant activation (or over expression), which is associated with uncontrolled cell division and the development of advanced NSCLC.
About Boehringer Ingelheim in Oncology
Building on scientific expertise and excellence in the fields of pulmonary and cardiovascular medicine, metabolic disease, neurology, virology and immunology, Boehringer Ingelheim has embarked on a major research program to develop innovative cancer treatments. Working in close collaboration with the international scientific community and a number of the world's leading cancer centers, Boehringer Ingelheim's commitment to oncology is underpinned by using advances in science to develop a range of targeted therapies for various solid tumors and hematological cancers. The current focus of late-stage research includes compounds in three areas: signal transduction inhibition, angiogenesis inhibition and cell-cycle kinase inhibition.
For information about participating in a Boehringer Ingelheim clinical trial, please visit www.bicancertrials.com or call 1.866.725.7110. Healthcare providers interested in learning more about Boehringer Ingelheim clinical trials in oncology can visit www.inoncologyus.com for additional information.
About Boehringer Ingelheim Pharmaceuticals, Inc.
Boehringer Ingelheim Pharmaceuticals, Inc., based in Ridgefield, CT, is the largest U.S. subsidiary of Boehringer Ingelheim Corporation (Ridgefield, CT) and a member of the Boehringer Ingelheim group of companies.
The Boehringer Ingelheim group is one of the world's 20 leading pharmaceutical companies. Headquartered in Ingelheim, Germany, it operates globally with 145 affiliates and more than 44,000 employees. Since it was founded in 1885, the family-owned company has been committed to researching, developing, manufacturing and marketing novel medications of high therapeutic value for human and veterinary medicine.
As a central element of its culture, Boehringer Ingelheim has a demonstrated commitment to corporate social responsibility. Involvement in social projects, caring for employees and their families, and providing equal opportunities for all employees form the foundation of the global operations. Mutual cooperation and respect, as well as environmental protection and sustainability are intrinsic factors in all of Boehringer Ingelheim's endeavors.
For more information, please visit http://us.boehringer-ingelheim.com and follow us on Twitter at http://twitter.com/boehringerus.
1U.S. Food and Drug Administration. Fast Track, Accelerated Approval and Priority Review. Available here: http://www.fda.gov/forconsumers/byaudience/forpatientadvocates/speedingaccesstoimportantnewtherapies/ucm128291.htm. Last accessed December 5, 2012.
2U.S. Food and Drug Administration. Developing Orphan Products: FDA and Rare Disease Day. Last accessed December 11, 2012. Available here: http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm107293.htm.
3Solca F et al. Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker. Journal of Pharmacology and Experimental Therapeutics. Published August 20, 2012.


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As a practicing endocrinologist, I write with heavy heart regarding your article on medical insurance ("Maryland braces for Supreme Court decision on health care reform law," June 19). Through the years of recession, several patients of mine lost their jobs and could not afford their office co-pays.
Unfortunately, among them were people with diabetes, high blood pressure and heart disease. Even those with insurance had high deductibles and had to meet the cost of an office visit up front. Increasingly, insurance coverage cannot be equated with medical care.
Many patients, burdened by medical bills, are skimping on care and cutting back on office visits. But one case stands out in my mind. This is a patient who worked a back-breaking job in a warehouse. When he could no longer lift heavy weights after developing severe diabetes that required Insulin treatments, he lost his job.
He managed to get medical assistance through the state. He has a primary care doctor, and since his diabetes was in such poor control he came to me for specialty care. By that time he had no home. His family didn't want him.
He was not using drugs — his drug screen was negative — and he didn't drink alcohol. He ate one meal a day if he ate at all. He had a cell telephone through an assistance program but no transportation to go anywhere.
He called a medical assistance cab to get to his doctors' appointments, but when he started living in the woods and moving in and out of shelters, he had no longer had an address to give to the cab drivers who picked him up for his doctor's appointments.
When I ran his blood tests, I discovered that his debilitation and severe loss of weight came not only from diabetes but also from a condition called adrenal insufficiency. Not only could I not reach him to tell him this, but I could not even send him a letter. When he finally called me, he told he could only talk a few minutes because his cell phone's reception in the woods, where he now lived, was poor.
I told him about his blood tests and asked him where I could call in his medicines. He did not know when he would have transportation to get to a pharmacy and asked if he would die without it. I told him he could indeed die and perhaps he should get to a hospital immediately.
Since that time I have been calling the hospital to which he promised to go, but apparently he never got there. I couldn't call social services about him because he didn't want me to, and I also did not know his exact location.
This is the state of so many patients in the United States today. Poverty feeds poverty. We live in a society where insurance is not enough. It should be backed up by shelter, transportation, access to communication and a support system that helps people who are sick and desperate.
My heart breaks for this man. I left India years ago, when excruciating poverty there overwhelmed and paralyzed even the most charitable folks who wanted to help. Today in my profession in the U.S., each day I sense the India I left.
For many Americans, this is certainly the Third World. As we wait for a decision about the Affordable Care Act from the Supreme Court, it's important to realize why medical insurance, even Medicaid, is small comfort to patients like the one I have described.
Usha Nellore, Bel Air


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The Constellations
AlbumsSee All
Music VideosSee All
Singles & EPsSee All
CompilationsSee All
About The Constellations
Led by vocalist Elijah Jones, the Constellations specialize in eclectic, rhythmic electro-rock that recalls the sounds of Beck, Gnarls Barkley, and the Heavy. The Atlanta-based collective features a rotating lineup of local pop, hip-hop, and rock musicians, several of whom -- including Cee-Lo and rapper Asher Roth -- contributed to the bands debut album, Southern Gothic. With Jones calling the shots and Grammy-winning producer Ben H. Allen behind the boards, Southern Gothic was recorded in 2008 and released by Allens own label, Make Records Not Bombs. The Constellations reissued the album two years later, this time with the support of EMI. In 2012, the Constellations returned with their sophomore effort, Do It for Free, featuring the single "Right Where I Belong." ~ Andrew Leahey
- Atlanta, GA
- Alternative
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Hi everyone! I have some adorable white bow nail art pieces from Born Pretty Store for you today!
I started off with two coats of Cult Nails Faded, a very pale grey creme, and two coats of Cult Nails Fetish, a black wax finish creme, on my ring fingers.
I used my largest dotting tool with Faded & Fetish for a contrast dotting look. I am so into big dots right now!! They're so simple, but so much fun to wear!!
I applied one coat of Cult Nails Wax That top coat, and then I used nail glue to apply one of the bows to my ring finger. It bonded immediately and the glue didn't damage the white backing of the bows, which is something I've had trouble with in the past.
I am crazy about these little bows!! I thought they might be a bit too large and easy to knock off of the nail, but they're definitely not!!!! I have bumped my finger at least twenty times, and these little bows are still going strong after four days! I cannot wait to try the other styles!!
You can find this ten piece set of bows and other awesome nail art add ons and tools at the Born Pretty Store here. You can also use code DQL91 to receive 10% off of your total order!
Happy Painting!
*Products provided for the purpose of an honest review*


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What is self-discipline and why do we need it?
My kids and my husband were off to do something fun, and I readily admit, I wanted to go and share their afternoon with them. I wanted to be with those I love, have some fun, and see and hear about what they were enjoying.
However, somewhere in my brain, and perhaps my heart, I knew I had work to do and I also knew I needed to get it done while I was fresh and alert. At the end of a tiring and busy day, my writing would suffer.
So, I opted to stay home and write and sent my family on its merry way to enjoy beautiful Southeast Texas together. This decision caused me to begin thinking about self-discipline and why some have it and some never seem to get it. How does one acquire a good dose of self-discipline? Is it necessary for success? Are there areas in our lives where we know we have not conquered the matter? (By the way, I don't always make the right decision and exercise self-discipline about a matter, but I am working on it even at this stage in my life. I am also trying diligently to teach my grandchildren about the trait and how important it is to their young lives.)
I read many definitions of self-discipline, some by famous orators and others by friends who were willing to share their thoughts with me. I have combined some of the best thoughts and want to share them with you. I believe that self-discipline is the ability to motivate oneself in spite of negative surroundings, peer pressure, or our own emotional state. The three attributes I associate with it are willpower, hard work and persistence.
One man wrote that self-discipline is the product of persistent willpower. And willpower is the strength and ability to carry out certain tasks in the manner you have chosen for your life. When we exercise self-discipline based on character choices we have carefully made, we then can count on our self-discipline to step up to the plate and handle the situations we face daily in life. And yes, it is very necessary for any measure of success in anything we undertake to do.
Riding home in the car from a day trip to Lake Charles, I was talking earnestly to my almost 14-year-old granddaughter. Callie is beautiful, bright, fun, intelligent and has lots of friends. We jokingly say she is the social butterfly of our family, and there's seldom a long span of time that she doesn't receive phone calls and texts from friends. She went to a private Christian school before deciding to finish her high school education in a large public school where she can take part in a broader music, drama and science program, as well as other academic explorations. She has a tiny bit of anticipation about her choice, but feels strongly that it is the right one for her. Both of her parents agree.
I did my best to teach her that she has enough self-discipline in her young life to make good choices based on what she has been taught. I also told her that she would very likely face peer pressure to participate or become involved in things that are not best suited for her. And I urged her to rely on her own self-discipline to overcome the temptation.
Callie seemed to understand the need for self-discipline, and I am praying for each of my grandchildren as they start a new school year. I honestly think we, as adults, have no idea of the pressures that are on the children of our generation. While we're praying, let's also remember our teachers and administrators, coaches, staff members, bus drivers and medical personnel that work with our kids. This is a different world than many of us grew up in, I have come to believe.Oh, that the adults practiced self-discipline in many of their life choices as well.
Brenda Cannon Henley can be reached at (409) 781-8788 or at brendacannonhenley [at] yahoo [dot] com.


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The upgraded maneuvering and seakeeping test facility in West Bethesda, Md., can produce waves up to 4 feet tall, holds about 12 million gallons of water and can simulate most sea conditions from open ocean to shallow water. (Mike Morones/Staff)
A revamped Navy facility is making waves to see how ships fare in the unpredictable conditions out on the ocean.
Officials unveiled the new maneuvering and seakeeping, or MASK, facility at Naval Surface Warfare Center Carderock, Md., on Dec. 19, which simulates the kinds of waves sailors might encounter underway and tests how ships would handle them.
"The engineers in this facility for the past 50 years have evaluated the maneuverability, stability and control of virtually all of our surface ships and submarines in the fleet today," NSWC Carderock division commander Capt. Rich Blank said at the ribbon-cutting ceremony.
Six years ago, the facility embarked on a project to update the MASK basin wavemaker, which tests scale-model components of ships, platforms and onboard systems in realistically re-created sea conditions.
The remodel upgraded the basin from a pneumatic system that used air pressure to create waves to a set of 216 individually controlled, electro-mechanical boards that act like fingers in the water, adjusting to create multiple wave types from multiple angles.
"In this facility, we can test scale models up to 30 feet in length in order to predict the full-scale performance of ships in the open ocean," said Joseph Mueller said in a news release. Mueller is the head of NWSC Carderock's hydromechanics facilities engineering and operations division.
The pool measures 360 feet long by 240 feet wide by 20 feet deep, holds approximately 12 million gallons of water and can produce waves up to 4 feet. The 10-by-2-foot wave boards can also mimic the conditions in shallow water for testing littoral combat ships.
Underneath the water, a tow carriage can pull ship models through the basin in head or following seas at any angle, at a speed of up to 15 knots.
"This upgrade, along with the size of the facility, makes the MASK the most advanced test facility of its kind in the world," Jon Etxegoien, NSWC Carderock naval architecture and engineering department head, said in a news release.
Rear Adm. Lawrence Creevy, commander of Naval Surface Warfare Center, took the floor at the ceremony to provide a little context for the giant pool of water in the 5-acre testing facility.
"Just in the past year, our Navy and Marine Corps team have conducted a full range of military operations, including combat in Afghanistan, security cooperation management in the Pacific, disaster recovery operations in the Philippines and ensuring safe lines of communication around the world, just to name a few," Creevy said.
The many kinds of ships used in these operations get their start at Carderock, he said, years and sometimes decades before they hit the open water.
Creevy mentioned the dry cargo ship Charles Drew and littoral combat ship Freedom, which were both tested at Carderock in recent years and deployed to the Philippines in November to join Operation Damayan, the military's joint typhoon-relief effort.
It's also these facilities, Creevy said, that "enable our Navy to operate at such an unrelenting pace around the world."
"In short, the United States Navy starts here."
By Meghann Myers


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Batkid will return to Gotham City -- err... San Francisco.
This time, it won't be to arrest the Penguin or to capture the Riddler.
Five-year-old Miles Scott of Tulelake, Siskyou County, will arrive in San Francisco (most likely in the family van instead of a decked-out Lamborghini ) on Saturday to cheer folks on at "Brave the Bay," formerly known as the SFPD Challenge, Make-A-Wish spokeswoman Jen Wilson said Thursday.
MORE: SF Morphs into Gotham City for Batkid Battling Leukemia
Batkid, aka Miles, will lead the "Santa Walk" with his family, who recently set up a "Batkid Fund" to support three groups that helped him during his treatment.
The shy kindergartener with bright blue eyes was last in town on Nov. 15 when he was the recipient of an internationally inspiring volunteer effort, noted by everyone from the Harlem Globetrotters to President Obama.
While sick with leukemia - from which he is now in remission - Miles told the Make-A-Wish people that he wanted to be "Batman for a day." He was able to realize his dreams and beyond when 12,000 volunteers got wind of his request, and the city of San Francisco morphed into Gotham City for a day.
Now, Miles is helping the police officers realize their goal to raise $75,000 to help grant wishes for 357 children with life-threatening medical conditions. Organizers are hoping to help 10 children on Saturday alone.
MORE: "Batkid Fund" Created to Help Other Sick Kids
The police-run Brave the Bay, now in its 6th year, features a 5K Santa Walk/Fun Run, a Santa plunge in the bay and the Santa Car Pull. Participants can join in either one event or all three to complete the "Santa Triathlon. Each event costs between $25 or $60 for all three.
Miles' parents, Nick and Natalie Scott, said in a statement that it seemed "only fitting that following a day when the world demonstrated caring and compassion for Batkid, Batkid can now help others."
Brave the Bay runs from 8:30 a.m. to 1:30 p.m. at Aquatic Park at Jefferson and Hyde Streets. To register, visit www.bravethebay.org.
All locations are Aquatic Park, Jefferson and Hyde Streets.
- Santa 5K Walk and Fun Run: 8:30 a.m.
Batkid Miles Scott and family will be lead lead the walk.
- Santa Plunge in the Bay: 10:30 a.m.
This also includes the Executive Challenge, where local CEOs, along with Police Chief Greg Suhr, will be plunging in order to fund individual wishes.
- Santa Cable Car Pull: 11:00am-1:00 a.m.
Teams of up to six people compete to see who can pull a cable car the fastest. The challenge is to beat the SFPD teams.
- Cops & Coffee: 9:00am-3:00 p.m., Buena Vista Café
Enjoy a traditional Irish Coffee served by San Francisco police. All tips will be donated to Make-A-Wish.


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The Basics of Commodity ETFs
Exchange-Traded Funds, or ETFs, offer many advantages to commodities investors because they offer exposure to asset classes and specific investments that would otherwise be difficult for the average investor to access, such as uranium or palladium.
In addition, they give you a broad diversification platform because they can track a basket of stocks or commodities. This characteristic is a major reason ETFs have become so popular in the last decade, increasing from several dozen to more than 2,500 ETF products.
Unlike a regular mutual fund, in which the net asset value is generally calculated at the end of the trading day, the ETF enables you to trade throughout the day. Furthermore, you can go both long and short the ETF, something you can't do with regular mutual funds.
It's critical to perform extensive due diligence on any ETF product you're considering for your portfolio. You need a solid understanding of the underlying assets in the ETF. Often beginning investors simply browse the description without getting a good grip on what they're actually buying. For example, the current uranium ETF URA (NYSE: URA) isn't a product that tracks uranium metal prices; it tracks a basket of uranium-mining equities.
Folks who don't get into the fine print may miss basic yet critical pieces of information regarding ETFs specifically and broader investment products in general. Make sure you go beyond the headlines and into the fine print!
ETFs aren't free, in the sense that they're actively managed products associated with a financial institution. ETF sponsors generally charge an added layer of fees for the convenience of using their products. Therefore, it's imperative to know the types of fees associated with each ETF you purchase. This information is conveniently located in the fund's prospectus.
Deutsche Bank launched the first commodity index ETF in the United States in February 2006. The Deutsche Bank Commodity Index Tracking Fund (AMEX: DBC) is listed on the American Stock and Options Exchange (AMEX) and tracks the Deutsche Bank Liquid Commodity Index (DBLCI). The DBLCI, in turn, tracks a basket of six liquid commodities:
Light, sweet crude oil (35 percent)
Heating oil (20 percent)
Aluminum (12.5 percent)
Corn (11.25 percent)
Wheat (11.25 percent)
Gold (10 percent)
Clearly, the DBC is a superb indicator of the broader commodity markets. The story of commodities since 2005 is characterized by a massive run-up in prices, driven partly by large consumption demands from emerging markets such as China and by speculative activity. That price run-up resulted in a massive bursting of asset bubbles in 2008 during the Global Financial Crisis.
Commodities, like almost every other tradable asset class, suffered a shocking downward dislocation when liquidity dried up; the DBC accurately portrays this turn of events.
The DBC ETF is structured as a commodity pool operator (CPO), and the fund invests directly in commodity futures contracts. To capture additional yields, the energy contracts are rolled monthly; the rest of the contracts are rolled annually. The fund also invests in fixed-income products, including the three-month Treasury bill, which provides an additional yield for investors. With an expense ratio of 1.5 percent, it's a reasonably priced investment.


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Algeria law seen as blow to women's rights
Glory days for soccer in tiny American Samoa
2011 a year of success for Angolan women
Anguilla turns to TVET for more job skills
British adventurer sets out to become first woman to make solo crossing of Antarctica
Disaster Co-ordinators Recognised
Women's role issues discussed in Armenian government
Promote Youth Empowerment to Reduce Brain Drain (Opinion)
Marcus Samuelsson in Barbados Gives Lessons on Eating Well
Women Launch 16 Days Of Activism
West Africa Plans "Electricity Interconnection"
Where are the snows of yesterday?
The prime heritage trails of Botswana
WWF says 40% of Borneo's forests can be managed by firms
Forest Communities in Burkina Faso, Ghana and DRC to Benefit From Dedicated CIF Grant (AfDB)
Cameroon Sentences Three 'Effeminate Men' to Maximum Prison Time
Cape Verdean kitesurfers challenge home waves
'Crazy Idea' guys start their run
Africa's ousted dictators live high on the hog while nations bicker over trials
Australia to release 100 boatpeople a month
Satellite Survey Sheds Light on Species' Extinction Risk
Cooks signs deal with China for exploratory fishing
Djibouti Diarrhea Outbreak Has Affected Thousands
20,000-year-old fishhooks found in East Timor
Eritrean diplomat defects to Canada
Falkland Islands hope for tourism boost after news of Prince William's tour of duty
Two suspected murder cases in the Faroe Islands
In Latin America, Effective Regulations Bolster Energy Boom
Jammeh re-elected Gambian president in polls, ECOWAS alleges intimidation
IBM opens Ghana centre to grow business in 17 African countries
Polar ways of life 'disappearing'
Ways to improve Guam's public schools
France pardons Guinea Bissau's debt
Living and struggling in Guyana
Women's Empowerment Event in Reykjavík
Pair adrift in Pacific for over a month
Kyrgyzstan moves to stop 'bride' kidnappings
Laos Human Rights Advocate Dies
Film about friendship hopes to inspire
Ellen Declares 16-Days Action Against Gender Violence
Air France's commitment in Madagascar
Malawi study reveals climate adaptation costs
Women's contribution possible only by eliminating gender disparity: President
Climate Investment Fund Board approves Mali's $40m plan to scale up renewable energy
New cases of dengue fever in Marshall Islands confirmed
108 Countries Support HFC Curbs under Montreal Protocol
Moldova issues stamp to mark 60th anniversary of refugee convention
Vogue India: Art or Exploitation?
Montenegro: IMF requesting reforms in the labour market
Mozambique launches US$2bn power project
More Needed to Access Higher Education
The shark, a predator turned prey
WHO warns of untreatable tuberculosis
Seychelles proposes a new energy bill to revolutionize electricity provision
I will not resign: Solomon Islands PM Lilo
Citizens of Suriname Celebrate Their Independence Day
Calling all men, calling all leaders
HIV group N case detected outside Cameroon for the first time
Governments plan for HIV/Aids insurance can hit snag
Turkmenistan begins supplying gas to southern China
Western nations 'used bullying tactics' at climate talks
Regional issues to personal drama in Arabian Nights Film Festival
Vanuatu's WTO membership vote further delayed
Hundreds Protest Living Costs in Wallis and Futuna
Concerns over cost to EU and Morocco occupation of Western Sahara


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Hidden Conflicts of JAMA Authors Exposed
Statement of CSPI Integrity in Science Director Merrill Goozner
Two years ago, the Center for Science in the Public Interest warned the editors of the Journal of the American Medical Association and other leading scientific journals that there was a persistent pattern of non-disclosure of conflicts of interest by researchers publishing articles within their pages. CSPI said that a voluntary disclosure policy needed teeth if it was going to work. Our concerns were ignored.
Today's Wall Street Journal documented a major failure to disclose relevant conflicts by seven authors of a JAMA article involving the safety of anti-depressant use by pregnant women. At least two of those authors, including lead author Lee S. Cohen, a Harvard Medical School professor and director of the perinatal and reproductive psychiatry research program at Massachusetts General Hospital, had their conflicts of interest documented in CSPI's Integrity in Science Database at www.integrityinscience.org prior to publication of the article.
It's clear that the Journal of the American Medical Association does not evaluate conflict of interest disclosures when articles are submitted. As a result, some authors with blatant conflicts of interest apparently feel they can ignore the journal's policy with impunity.
The only solution is for journals to adopt strong penalties for authors who fail to disclose – a three-year ban from publishing in the pages in the journal (such a policy has been adopted by Environmental Health Perspectives). The International Committee of Medical Journal Editors should also make a ban by any of its members apply to all its members.
Contact Jeff Cronin (jcronin[at]cspinet.org) or Ariana Stone (astone[at]cspinet.org).


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Emmanuel Lions Lockup
The Emmanuel Lions Wordmark Lockup should always be used in one of the color combinations shown here. One color print situations may be an exception, but must be approved by the Brand Committee. See the "Colors" page for approved color and background combinations.
Files for printing these logos may be obtained in the CRIS Registration System under Forms and Documents -> Branding Support Team.
To request a high-resolution version of any of the logos shown below, please click here.
To download a low-resolution version of any of the logos below, right-click on the logo and choose "Save Image As."
One Color (White is transparent)
Two Color (White is solid)
Two Color (White is transparent)
Three Color (White is solid)
Three Color (White is transparent)
Four Color (White is solid)


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(And MP3 http://tinyurl.com/pdvvhfg)
I don't imitate much voices and sounds (especially done by little Iulia). I considered making a high pitched "Lalla", but it would sound in the overal recording too funny (and I would have to speak like that as Iulia). I was also considering slapping myself instead of tuxtax... but again
CAPITULUM II - FAMILIA ROMANA - http://youtu.be/Fb1aJEh2lUo
(And MP3 http://tinyurl.com/nlwvzwn)
I also deal with the problem of the feminine version of "Quis?" (=Quae) (an interrogative substantive) which [edit] seems not to be a classical way for an interrogative substantive at all, with "Quis?" being used for both genders. So I pronounce the sentences both with "Quae?" and with "Quis?" (which is my opinion desired).
CAPITULUM I - IMPERIVM ROMANVM - http://youtu.be/tt3g90nCgPk
(And an MP3 http://tinyurl.com/oqr27s2 ; and no-background-noise MP3 tinyurl.com/lwd84sa , the audio quality is worse here, I recommend the original version.)
- I recorded it with my headphones on, so the result is a kind of a "silent tranquil voice mode", but I find it (perversely) pleasant when listening with headphones.
I will probably do the whole book...
So the point was to have there on the Internet some recordings of the Lingua Latina Per se Illustrata: Familia Romana that are:
1) different than the recording done by the venerable but very old and tired voice of Hans Oerberg (It sometimes makes an impression that Latin must be truly dead)
2) restituted pronunciation
3) correct pronunciation
4) correct vowel lengths: not to pronounce a vowel long which should be short, not to pronounce short which should be long, not to pronounce something long just because it is accented (unless long in the same time), not to aspirate consonants (like "p,t,k") that shouldn't be aspirated, always voice the initial voiced consonants (like "b"; as in "barba"), to have some reliable vowels, no vowel reduction (no schwa thing), no diphtongization of the long vowels... etc.
5) My native language is Czech which is described sometimes as the one of the European languages having phonemically a long-short vowels pairs distinction (for all the vowels we have), so it could be more interesting for you. (Slovak also has it, but Slovak for example has problems with words containing more than one long vowel, Czech can have a word with 4 long vowels no problem). We for example always recognize a long vowel even in a rapid speech.
6) the voice shouldn't be annoying (and I hope I'm not: I've also bought a new microphone )
7) the recordings are available in MP3
I realize that I have deviated a tiny little bit in very few aspects from what is prescribed in the Vox Latina book, but it is so marginal that you wouldn't know.
Nevertheless I list all the deviations I'm aware of in the video description on Youtube:
(by the way: I mention English speakers a lot, but it is a bit unfair, because the reason is that they are the Latin speakers I meet the most as I move mainly on the English internet. So the English speakers will forgive me )
Familia Romana recordings that are alternative to Hans Oeberg recordings (a different and much younger voice). The stresses/accents and vowel lengths are ALWAYS adhered to. So you can imitate it
Download the MP3 http://tinyurl.com/oqr27s2
The pronunciation: I do adhere to the restituted rules quite rigorously but there might be some deviations I know about and I am going to list them:
1) The vowel inventory used for my restituted pronunciation (the long and short monophtongs I use) is this http://tinyurl.com/p7y86en . It is not 100% what the book (Vox Latina) prescribes but it is daringly close (much closer than the English vowel inventory for example). The only difference between my way and the prescribed way is that my long vowels are always identical to the short vowels (the same vowel quality) and differ purely only by the length (different vowel quantity), unless for "í/ī. Sometimes it might happen that I will use a vowel which is identical to what is prescribed by the book.
But you will probably hear no difference.
2) I do not turn final vowel+m (um/em/am) into a nasalized vowel both for higher clarity of the recording and mainly because I do not hear anybody from the latinists I talk to to do that very much unless they read poetry. Also Vivarium Novum teachers, as far as I know, do not do this. (And Vivarium Novum is the biggest known community speaking only Latin)
3) I do not produce "QU" as labiovelar stop, because the majority seems to ignore this also. We produce instead a sequence of two sounds "Q + W" as in Italian: so my pronunciation is not exactly what the book (Vox Latina) would prescribe but it is what you will hear in the restituted pronunciation all around the world (both from lips of academics and amateurs). To be honest I have never met (or heard) anybody to do here a real labiovelar stop.
4) My mother tongue does not aspirate certain consonants: "p,t,k" which is GOOD for Latin and this recording is therefore also very beneficial for English speakers who tend to do this and usually do it also in Latin, even if they try to avoid this. Terence Tunberg, maybe the best latinist in the world, also does it sometimes and that makes him distinctively sounding English when speaking Latin.
5) My native tongue never reduces vowel / does not turn them into schwas, so this is again very beneficial for the English speakers. E.G. I would never pronounce "animus" as "anim-s", which when unreduced, is correct.
6) My initial consonants that are supposed to be voiced, like "b" in "barba", are always voiced. English speakers tend to produce them as unvoiced and unspirated, so this will be a good example for them.
7) the classical diphtong "AE" is not supposed to be exactly the same as the first vowel in the word "island" but it is supposed to be something as "a" + suppressed "e". But I will probably not always adhere to this. The audible difference is marginal. Same with "oe".
I never pronounce long vowels (monophtongs) as diphtongs as English speakers tend to do. So my "ē" is never "ei", my "ō" is never "ou", etc.
9) I pronounced 'Lesbos' with "z". This was not on purpose... it is what we call in phonetics an assimilation of voicing. ("b" is voiced, ergo "s" will be voiced too). Maybe the Greek pronunciation of that time had this (but I do not know).
If something else occurs me, I will write it down. I hope you will enjoy it.
As I mentioned, the recording is done with my headphones on, so it is done with a silent voice in a way which gives it an interesting color, but I think it is not exactly unpleasant
- I have not removed the background noise because the voice would suffer a bit.


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Unknown Unknowns
MartinPacker 11000094DH Visits (8838)
Nope, I'm not going to do a Rumsfeld. :-) But there are a couple of things I didn't know (I didn't know) about DFSORT. Relating them to you is probably OK because It's not something I'm embarrassed about.:-) If you want to understand some of the funkier new DFSORT tricks you probably need to know these things. Consider these DFSORT examples (which I take no credit for). They are used to deal with... [More]
Parsing XML with DFSORT
MartinPacker 11000094DH Comments (6) Visits (20448)
Following on from Generating XML Using DFSORT - Part II here are some thoughts on how to parse XML with DFSORT. NOTE: For more complex XML than this entry describes you probably want to use the XML Toolkit for z/OS . This provides C++ and Java parsers for XML and a stand-alone XSLT processor. In this example I'll show you how to take XML that looks like this and create a flat file from it:... [More]
Generating XML Using DFSORT - Part II
MartinPacker 11000094DH Comments (2) Visits (11305)
In Generating XML Using DFSORT - Part I I described how to generate XML using some of DFSORT's new features. But the XML we generated was only one of the possible styles of XML: Most of the information was specified as attributes (with the values enclosed in quotes). Here's a sample line: <member surname="Mercury" firstname="Freddie" job="Singer" /> In this case the attribute job has the... [More]
Generating XML Using DFSORT - Part I
MartinPacker 11000094DH Visits (9525)
Following on from This entry on creating CSV files here's the first of several entries on manipulating XML with DFSORT... This is not intended to be a tutorial on XML but rather an exploration of how DFSORT can read (shred) and write (compose) XML. (I also use the terms ingest and emit synonymously.) Hopefully some of the basic concepts of XML will come across during the course of these blog... [More]
Using DFSORT to create CSV files
MartinPacker 11000094DH Comments (3) Visits (32393)
I plan on writing some entries on creating and parsing XML with DFSORT (using the UK90006 / UK90007 functional enhancments that DFSORT Development recently announced). But here's a limbering up example - creating a CSV file from regular sequential file input. CSV files ( C omma- S eparated V alue (or V ariable if you prefer)) are of the form "JDLFJDJ DF",4146,"FKJFK" "JDJDJ JKJJ",12352,"EE... [More]
Search and Replace with the new DFSORT functional PTFs
MartinPacker 11000094DH Comments (2) Visits (25540)
Here's my first tip with the new UK90006 / UK90007 DFSORT PTFs. It's an apparently minor enhancement that I think people will like... It leads to a more elegant syntactical expression. It is more maintainable - in the face of changing record layouts. Suppose you want to search a file for a string in a particular position in each record and replace all matching instances with a different string. (... [More]
DFSORT New Function PTFs
MartinPacker 11000094DH Comment (1) Visits (7827)
As many of you know I like to beta DFSORT function PTFs. About once a year a new set of functions appears, many in direct response to customer requirements. Occasionally some of the enhancements are at my suggestion. :-) Yesterday PTFs UK90006 and UK90007 became available. (Being UK based it's nice to see PTF numbers beginning with UK but I read no significance into this.) :-) You can read the... [More]


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Jun 26, 2019
- Shravan Bhat
HOUSTON--A senior power trader has left Citi's commodities group after about six years with the firm.
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Oct 04, 2019 - Power Finance & Risk
The annual Siemens Energy Financial Services Oktoberfest bash in New York settled into a new venue this year at the Ziegfeld Ballroom, a recently repurposed former movie theater in Midtown Manhattan.
Aug 30, 2019 - Power Finance & Risk
The #PowerTweets feature tracks trends and news in power and energy on Twitter. For more news and coverage, follow @PowerFinRisk on Twitter, as well as editor @richmetcalf and reporters @Shravanbhat, @Taryana_Odayar and @ArroyoNieto.
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Advent Calendar of Christmas Memories for December 8
Christmas Cookies
Christmas Cookies
This Blog is pleased to join with other GeneaBloggers around the world in presenting this Advent Calendar over the next 24 days leading up to the Christmas celebration - a different topic each day. We will attempt to post on each of the topics. Our invitation continues to be open to other writers to join us here with your comments (See Nov 29, Dec 5, Dec 12, and Dec 19 posts here - laber 'Advent Calendar' - for the topics; or the link in the title, here).
Christmas Cookies
I wrote about Grandma (Sporensen - born in Denmark) Kinnick's Christmas Cookies under the Holiday Food prompt, but I'll add one more comment here, under Christmas Cookies - especially since her cookies were good, year around!
A real favorite, that she didn't make that I recall in the later years - therefore, from my younger years, was: I don't know the name, but they were really good. I'll have to just describe them.
I think she used a 'donut' cookie cutter, but just a hole on the top, not on the bottom. It was good, sweet, cookie dough They were good sized around, not skimpy. The whole as about the size of a quarter, and was not 'large' on the cookie! I think I must have helped make them, as a youngster, or at least watched real close. The whole circle was laid out, and a filling of raisin 'stuff' was spread on, not real thin... some body to it. The top was then put on, so that the filling showed through the hole. It was pressed around the edges so that the filling was only exposed in the hole, in the middle. Baked. I loved them. They weren't favorites of others in the family, so lost out, in the long run. But, for me, those were the best.
What were your favorites?
Families are Forever! ;-)


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The skateboard store where two employees were killed earlier this year will reopen next month.
Zumiez says it made the decision to reopen its Columbia Mall location after consulting with the families of the victims.
On Jan. 25, Darion Marcus Aguilar, 19, entered the Zumiez store on the upper level of the mall and fatally shot 21-year-old Brianna Benlolo and 25-year-old Tyler Johnson, before turning his shotgun on himself.
Last month, Howard County Police revealed Aguilar was fascinated with the Columbine shooting, even timing his attack for the minute the Columbine shooting began.
Zumiez did not set an exact date to reopen but says it will be in mid-May.


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Fatal accident kills Orangefield woman
Jessica Evans, 28, of Orangefield died Friday night, Dec. 27, as the result of a fatal traffic accident.
According to a news release from the Orange Police Department, dispatch received the call at approximately 11:38 p.m. in reference to the single-vehicle accident. OPD, Acadian Ambulance Service and the Orange Fire Department First Responders responded to the scene in the 6300 block of S. Lutcher. Upon officers' arrival at 11:39 p.m., they observed a sedan with extensive damage and one occupant, the driver, Evans. Judge Janice Menard pronounced Evans deceased at the scene.
According to OPD Captain Cliff Hargrave, Evans' vehicle veered off the road and into the guardrail. Autopsy results are pending.


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Depression risk decreased as women reported drinking more cups of coffee. Women who drank two to three cups of coffee per day had a 15 percent less threat of future depression. Those who consumed more than 4 cups each day decreased their risk by 20 percent.


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HANOI, Vietnam — A melee broke out in northern Vietnam when more than 100 villagers prevented authorities from destroying chickens to stop the spread of bird flu, officials said Sunday as the country announced its second H5N1 case.
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About 100 villagers in Thuong Tin district just outside Hanoi overwhelmed police and health authorities Thursday and stopped them from destroying about 1,500 chickens smuggled in from China, said official Vu Van Dung.
As about 30 police and health officials removed the poultry from a truck to burn in a pit, the villagers — desperate for the income the birds could provide — grabbed the chickens and ran off.
"I told the villagers that the chickens had been sprayed with chemicals and were not edible, but they didn't listen," Dung said. "They grabbed chickens from us, and we were overwhelmed."
Meanwhile, in northern Quang Ninh province, tests results confirmed Friday that a 23-year-old woman was infected with the H5N1 virus.
Bird flu basicsShe was on a respirator since being hospitalized five days ago, hospital deputy director Nguyen Quoc Hung said. The woman became ill after slaughtering and eating chickens her family was raising.
Five other family members who had also eaten the chicken showed no symptoms.
In early January, an 8-year-old girl from northern Thanh Hoa province tested positive for bird flu, Vietnam's first reported human case in more than 10 months.
Bird flu has killed 52 people in Vietnam, including five last year, since it began raging through Asian poultry stocks in late 2003.
The H5N1 strain has killed at least 254 people worldwide since 2003, most through contact with sick birds. Scientists are monitoring the virus because of its potential to mutate into a new human influenza virus, which could infect millions.
Copyright 2009 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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LeBron James still won't let 49ers' QB controversy die
Colin Kaepernick or Alex Smith?
That burning question divided San Francisco 49ers fans for several weeks following Jim Harbaugh's controversial decision to stick with Kaepernick when Smith suffered a concussion in Week 10.
Suffice to say, now that San Francisco is off to the Super Bowl after Sunday's 28-24 win over the Atlanta Falcons in the NFC Championship Game, the 49ers Faithful can feel united in their support of Kaepernick.
PHOTO:Kaepernick's parents in front of odd statue
WATCH:Jim Harbaugh loses his mind
Although LeBron James, of all people, was still driving a wedge moments after the Niners' triumph in Atlanta.
"Wanna know where all them damn so call know it all(critics) who said Coach Harbaugh was insane for starting Kaepernick over Smith #SuperBowl," he tweeted.
To James' point, the 49ers didn't just win the NFC title with Kaepernick; he led them there after they fell 17-0 in the second quarter. Kaepernick, who was 16 of 21 for 233 yards and a touchdown, kept his composure, though, making a bunch of big-time throws and selflessly handing the ball to Frank Gore out of the Pistol-Option with the Falcons keying on Kaepernick.
So, yeah, LeBron, you are right, but can we drop this story line already? Not a chance with two weeks of Super Bowl build-up.