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Capture your big day in motion.
Why choose Adam Beach Photography? Because we promise to work our absolute hardest to capture the story of your wedding day in the highest quality video and audio. This isn't uncle Joe with a camcorder. This is a priceless motion-feature film that your family will cherish for generations to come.
What is the final product?
There are all sorts of wedding packages available out there. Over the years we've found that most couples are looking for four things in their final product. Below you will find an example and description of these four videos you will receive if you choose our cinematic video coverage.
1. A Highlight Video
This is by far the most exciting aspect of our video package. Our videographer edits all the footage down into a 5-8 minute highlight video. The combination of breath-taking shots and voiceovers from the ceremony are 99% guaranteed to make you cry. Finally, our videographer hand-picks the finest licensed music to make it even more amazing. This video will be hosted online so you can easily share it with family and friends via social media or email.
2. A Ceremony Video
We hate boring ceremony videos. That's why we record our ceremonies with at least 3+ angles. Depending on the venue we use GoPro's to get some really cool shots from perspectives that would be extremely awkward for our videographer to capture.
3. Toasts Video
So you can forever remember that embarrassing story your best man or maid of honor told during their toast.
4. Additional Reception Footage
All the other footage that does doesn't make it into any of the other three videos. Candids of your guests, the whole first dance, the whole cake cutting, ect.
Meet Jake.
Based in Littleton, CO, Jake is our videographer extraordinaire who directs the whole filming process from shooting to editing. He's has all the latest and greatest video gear and has a passion for capturing your wedding day in breath-taking motion picture.


text: Indian owned multinational Tata started importing their Mercedes engined pick up trucks into the UK in 1994, appealing to a budget conscious customer. A small number of imports continued until 2005, by which time they also imported their Indigo hatchback models relabeled as CityRovers. Import ceased with the demise of Rover in 2005 and Tata have not imported any cars since but in 2008 Tata bought Jaguar Land Rover off Ford.

subset: commoncrawl


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Traditional bottle with a simple label topped with a cork – which I always love to see – and a tamper resistant sticker ribbon fastened across the top.
The uniqueness of this bottle rests in its simplicity – and in its elegantly placed tamper ribbon.
The rum poored smoothly into my glass and as I watched it fill I could smell the sweet aromas of sugar and molasses, and a hint of liquorice.
The first sip of this dark rum slid across my tongue and filled my mouth with delight. I let it roll down my throat and then exhaled a breath of sophistication.
My first sampling was straight. Occasionally I will sample my new rum on the rocks, however, I was so pleased with my first naked sip I couldn't imagine sipping it any other way.
This is not a mixing rum or one to be served on ice. It is a straight rum to be enjoyed in a mood of relaxation.
So relax, and enjoy it.


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So, you know, November is NaBloPoMo. Which sounds like something that might be vaguely dirty, but in fact isn't. Sorry. It's just a month of posting more to your blog.
And I was going to do this, post every day, get back in the blog routine. But oh, hello November 5 — you kind of snuck up on me! Just like those 4,000 pieces of Halloween candy. Were you guys working together or something? With Zombies?
But today, instead of posting something, I'm going to cheat and send you somewhere else. Go read this post:
Read it. And then, decide something important. Decide you're not going to jump to judgement. Decide you are going to be kind and loving to people who are different. No matter what your theology or what you think about "lifestyle choice vs. born that way," decide you are going to show love.
Decide you are NOT going to be the one who makes someone feel worthless. Decide you are going to be the one who treats everyone you come into contact with like a precious child of God. Because they are.


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Knock Off Spinners
Orson Equipment produce a range of spinners to suit a number of different makes and models. In addition to supplying spinners for Jaguar, MG, Allard, Austin Healey, and many other makes besides. Orson Equipment will produce spinners to specific customer requirement or design.
These spinners are made with quality uppermost in mind. Each spinner undergoes a rigorous quality check prior to chrome plating and again post chrome plating.
In addition to the standard spinners produced, Orson Equipment manufacture replica spinners for a wide variety of vehicles.
These are in keeping with the size and shape of the original. These can be ordered as a single set or as a multiple of sets. As ever quality is uppermost in the manufacturing process. Over the last 40 years Orson Equipment has manufactured an ever increasing range of spinners to suit an ever increasing demand.
On numerous occasions Orson Equipment has been approached to manufacture a special bespoke spinner.
Either designed by or commissioned by Orson or from a joint collaboration with the client to create a unique spinner on a unique project.
In keeping with the company philosophy quality is evident in these products.


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GOOD, Wooster Collective & Blu's Sketchbook/
GOOD Magazine and Wooster Collective have teamed up to bring glimpses of art for the masses, aka. graffiti. Really, it represents the mash-up of public spaces and any form of open source media: wall art, installations, ad "fixing", and eclectic personal projects taken to the streets.
Above is a video page-through of a sketchbook produced by the artist Blu. It is amazing on two levels: (1) the surreal images executed in clean, crisp lines and (2) the fact that this is just one of the hundreds of weekly sketchbooks Blu produces each year!


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Top Suggestions 90 Ford F150 Fuel Pump Wiring Diagram :
90 Ford F150 Fuel Pump Wiring Diagram The fun to drive nature of ecoboost engines is leading ford to introduce these fuel saving powertrains in large volumes virtually across its lineup for example by more than 90 pump ecm The fun to drive nature of ecoboost engines is leading ford to introduce these fuel saving powertrains in large volumes virtually across its lineup for example by more than 90 pump ecm The fun to drive nature of ecoboost engines is leading ford to introduce these fuel saving powertrains in large volumes virtually across its lineup for example by more than 90 pump ecm.
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San Clemente, California Dentist - Sachiko Fukuman, DDS - General and Family Dentistry
If you have any questions, concerns, or would like to schedule an appointment, please contact us using the information provided below.
Check us out on Facebook: Smile San Clemente!
We are a family oriented dental practice that enjoys the satisfaction of providing our patients with beautiful smiles and great oral health in a friendly and professional environment. Through education and preventative and restorative care, we treat each patient's individual needs to achieve a happy, healthy, and confident smile!
Office Hours:
Mon - Wed: 9:00am - 6:00pm
Fri: 8:00am - 2:00pm
Select Saturdays: 8:00am - 12:00pm
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My Ratings: 5 Stars
Cuisine: International/Hainan
Location: 362 Chulia Street, 10200 Penang
Pork Free
RM30-45 per person
Tel: +604 262 2177
Open Daily
Yeng Keng Hotel built in mid 1800's as a private residence of an Indian Muslim family is situated right in the heart of Chulia Street enclave beautifully and restored to its original 19th century splendour and more. Now turned into a world class boutique hotel with 20 elegantly appointed rooms. The hotel also house a cafe & bar which dishes out authentic Hainanese and international cuisine, ideal for a stay and dine vacation - a unique way to experience the Heritage of early Penang
Yeng Keng cafe & bar is one of a few places in Penang that serves authentic Hainanese fare. Typical Hainanese dishes like the Deep Fried Choon Pieh (RM12 for 2 pieces), Hainanese Mushroom soup with glass noodles (RM10 per person), Curry Tumis White Pomfret, Inchi Kabin (market price), Hainanese Chicken Chop, Chicken Pie and Yam Duck. All these dishes are my childhood favourites.
The Chicken Pie (RM25) is value for money. The portion serves 4 to 5 persons. For larger party of 10 persons, a larger portion of chicken pie is available for only RM35. All of the Hainaneses dishes is flavourful and not oily (good!). The Choon Pieh is the Chef Tan's recommendation. He stressed on the freshness and sweetness of the crab meat used. Chef Tan has more than 17 years experience in Hainanese cuisines.
Yeng Keng cafe & bar also serves a variety of international fare such as lamb shank, grilled fish with butter sauce, potato, onions and capers (RM18), sandwiches, soups & salads, pasta and local hawkers favourites. Must try are the lamb shank (RM35) and Beef Hor Fun (RM15).
The international menu is readily available but do call the hotel is you are planning to have Hainanese fare as pre-order is required until the Chinese restaurant is in full operation (located in the adjacent building).
One special dessert is the Bomb Alaska (RM20). This is a must order. Yeng Keng cafe is the only restaurant which serves Bomb Alaska in Penang that I know of. A common dish once upon a time but over the decades the popularity of the dish seemed to have disappeared. Maybe because it is hard to make (beating the egg white to a fluffy consistency and the "extra" effort to serve the dessert which included heating up the alcohol to be able to light it up and ooze all over the white which is a show by itself.
After dinner, one can proceed to the front garden of the hotel for drinks. The cozy outdoor offers a magnificent view of the picturesque hotel front all lighted up in full lighting effects. The bar offers value for money buckets of beer and is an ideal place for friends to gather and chat through the night
"Get Healthy and Feeling Fantastic with Maakoa's Koopuwa that's packed with highest anti-oxidant goodness"
Sunday, May 8, 2011
Invited Review: Yeng Keng Hotel
Posted by Alan at 8:56 AM No comments:
Labels: Best Penang Food, Chinese, Curry Fish, Dessert, Hainan, Hawker, Heritage, Hor Fun, Inchi Kabin, International, Penang Food, Pizza, UNESCO, Western
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Hi I'm Gerard, We're your local Drytron business for Hamilton, Portland and surrounding areas. We've been taking the drama out of carpet and upholstery cleaning for over 26 years. Unlike steam cleaning and some other cleaning methods, it's not all suds and water. When you have your carpets, furniture or drapes cleaned by a Drytron technician you're literally 'home and dry'. We use minimal moisture to avoid any problems of long-term drying, shrinkage and mildew.
Our aim is to reduce any disruption to your life. Drytron technicians are prompt and efficient, the process is rapid and quick drying, and our products are child and pet friendly. That's the Drytron way. Call us today on 13 12 50 or 0409 573 399.
The carpet dry cleaning method gets your carpets clean, and your family back into the living areas in no time.
Keeping your couches and upholstery at is easy with the Drytron dry cleaning process.
If you need your rugs cleaned in the Hamilton & Portland area, give us a call.
As your local Drytron technicians we strive to delight you with our service and the end result. We're part of the largest fleet of mobile service vehicles in Victoria and we cover suburbs in and around Hamilton from Portland, Broadwater, Digby, Hamilton, Mailors Flat, Penshurst, Portland, Sanford, Strathdownie and Victoria Valley.
At drytron we take your privacy seriously. Click here to view our privacy policy.
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Urban Fishing Lures - Making of from Giorgio Nasti on Vimeo.
From a basement in Italy, Urban Lures has started a little empire based on quality handmade balsa fishing lures. This is a really beautiful glimpse into his workshop by Giorgio Nasti a film maker based in Rome, lets hope he keeps pointing is camera at fishy subjects.
Currently Urban lures is selling through his facbook page (https://www.facebook.com/urbanfishinglures/) ,but a website is in the making. Meanwhile if the video doesn't wet you appetite enough check out the lure porn below.


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Live Reviews
Free Membership!
New Order Work On Next Album
Published: 2004-12-09
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The newest album from British band New Order can be expected to drop early next year. The band's eighth album, which at this point still remains nameless, is currently being recorded in Bath, England, and is nearing completion. According to an interview with NME.com, the new album will sound more like the dancey 1989 album 'Technique' than their more recent work.
The legendary outfit is working on the new record with equally legendary producers in Steven Street (The Psychedelic Furs, Blur, The Pretenders) and John Leckie (XTC, Simple Minds, The Fall). New Order's upcoming album is the follow-up to 'Get Ready', which was released in late 2001.
Not only can fans look forward to another New Order studio album in the near future, but the side project of bassist Peter Hook will also release a live album. The band is called Revenge and the album is called 'All Pain No Gain', set to hit stores on February 7th, 2005. The recordings included on the album are taken from two 1991 performances in Manchester, England and Kawasaki, Japan. Coming in at 70 minutes long, 'All Pain No Gain' houses 14 live tracks.
Formed in 1980, New Order rose from the ashes of beloved post-punk band Joy Division following the suicide of iconic lead singer Ian Curtis. Joy Division never intended to carry on if one of their members should leave for any reason, so the remaining members regrouped to form New Order. This new band would prove to be just as influential as Joy Division, taking on a different sound and releasing their debut album 'Movement' in 1981.
Writer: Jaclyn Arndt
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Tagged: Oswalt
Mariano Gets 500: Yanks Get Sweep
What a great win, huh? After the first inning, it looked like we were never going to score again, as Livan Hernandez was, for some reason, shutting us down. But Chien-Ming Wang turned in a decent outing and the bullpen was lights out from there. It's nice when you can take your starter out in the 6th inning and still have 5 relievers(Coke, Hughes, Bruney, Aceves and Robertson are all very fine relief pitchers) whom you can use to set up Mariano Rivera. I'm sure Girardi feels very comfortable with his bullpen right now.
However, we could use a complete game soon, because you don't want to use your bullpen everyday. Those guys have really earned a rest out there in the 'pen. Now, Joba Chamberlain is starting next game against the Mariners, so it's quite unlikely that he's going to pitch a complete game. And hey, since we have an off day today, that should be enough for the 'pen for now. But I don't like that we use them every day. I'd like to see Joba pitch a complete game, obviously, since he is capable of doing so. Let's face it, though, the only way Chamberlain's going to pitch a full game is if it's a no hitter. And even then, there are doubts.
Mariano got the 500th save of his career in the most extraordinary way: with his first career RBI. I mean, if Mo was going to drive in a run, you would think it'd be of the home run or double variety. That dude can swing it! But, Francisco Rodriguez, clearly screwed up by Rivera fouling a ball off, attempted to blow a fastball by Mo, and missed with two balls to walk him. That's just pure embarrassment, right there.
So now it's time to have a little off topic fun: before this season, in the month of February, I gave predictions on the awards and league leaders of the American and National Leagues. Today, with a day off, I'm going to look back at those predictions and, with the information that we have thus far as we head towards the All Star break, realize how dumb and wrong I am.
Cy Youngs: Oswalt and Halladay
I wanted to get funky with the Roy and Roy thing, and I'll tell you what, one of those predictions was pretty good. Who'd have thought Zack Greinke would be as dominant as he is this year? Oswalt, on the other hand… quite past his prime, definitely, but again, who could've seen Matt Cain be this dominant? Dan Haren, arguably, is better this season, and you could've seen Haren coming, but even with that, Oswalt was a dumb prediction.
MVPs: Miguel Cabrera and David Wright
Miguel Cabrera was a strong prediction, you have to admit, but Joe Mauer has been out of his mind since he made his season debut in May. He's just been off the charts. Now, Miguel Cabrera's had a very good season, too, and he does have a shot at making me right if he continues his Miggy Cabrera season and Mauer cools off, but the Wright prediction was not all too sound. Sure, Wright is leading the NL in hitting, but how could I have possibly picked someone other than Pujols?
You guys look at the rest and tell me how good my predictions were.
Thanks to Vanessa for hosting the game last night, it was real fun.
Stay positive, Yankee fans…
-EJ the Kid From New York


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Lucca Mini Single Sink Vanity
The simple style of European farmhouse furniture is echoed in this mini console with its paneled doors and sides, arched apron, and solid Carrara marble top and backsplash.
- 26" wide x 22" deep x 41" high
- Masterfully crafted with a solid-birch frame and finished with a hand-rubbed stain applied in layers for rich character.
- Top is made of 0.75"-thick Carrara marble, known around the world for its exceptional quality and natural beauty.
- Console is fitted with a white porcelain sink (included).
- Paneled double doors open to reveal open storage.
- Use with any of our faucet collections (sold separately).
- Professional installation required.
- Learn more about how to install this sink console.
- View our Furniture Brochure.
- Catalog / Internet Only.
Dimensions & Care
- Frame is beautifully crafted of hardwood and MDF, an engineered wood that lends exceptional strength, and ensures the console's structural integrity over time.
- High-quality Carrara-marble top and backsplash are white with grayish veining. The amount of veining and coloration varies from piece to piece.
- Console is fitted with a white porcelain sink (included).
- Equipped with drawers on each side to hold small items.
- Paneled doors conceal open storage and an adjustable shelf.
- Hand-rubbed finish is applied in multiple layers for a rich, vintage look, then sealed with a protective lacquer for moisture resistance.
- Console accommodates a standard 8"-widespread faucet.
- Can be installed with or without the included 5" backsplash.
- Overall: 26" wide x 22" deep x 41" high
- Wipe cabinet with a soft dry cloth.
- To protect the finish, avoid the use of all chemicals, household cleaners and abrasives.
- Clean marble frequently with a clean, soft damp cloth. Use a mild liquid detergent and warm water. To protect the finish, avoid the use of all chemicals and abrasives.
- The use of protective pads under heavy objects will help to prevent scratching of the marble surface.
- Avoid placing extremely heavy items on marble top.
- Consult with a professional at your local hardware store regarding marble sealer. Re-apply sealer every two years.
Shipping & Returns
UPS can deliver most in-stock items within 3-5 business days.
Next Day Delivery and Processing
We can arrange for next day delivery to most destinations within the contiguous 48 states, for an extra charge of $26.00 per address. If we receive your order by 6pm PT Monday through Friday, you'll receive your order the next business day; orders placed on Friday after 6pm PT through Sunday will arrive on Tuesday. Note: Next Day Delivery service is not available for some oversized items, White Glove Delivery, out of stock items, personalized items or for items shipped directly from the manufacturer.
View the complete Shipping and Delivery Information page.
You can return eligible item(s) within 30 days of receiving an order or 7 days for Quick Ship upholstery items for a refund of the merchandise value. An original receipt or gift receipt is required. Monogrammed items and Made to Order furniture or rugs are not eligible for returns. Review the full list of ineligible items and our refund policy below before starting the process.
Easy Ways to Return:
- Stores - You can return most non-furniture items to your local Pottery Barn store for free.
- Bring to UPS Location (under 70 lbs) – See our full Easy Returns Policy to start the process.
Ineligible Items
Items non-eligible for returns or exchanges:
- Monogrammed items
- Mattresses
- Gift cards
- Made to Order items, including custom rugs and furniture
- Final sale items (with prices ending in $.X7 or $.X9)
- Items damaged through normal wear and tear
Questions? See our full Easy Returns Policy.
Lucca Mini Single Sink Vanity
|Lucca Simple Single Mini Sink Vanity, Antique White
|No Longer Available


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Safe and Easy Laser Liposuction at Allure medspa
Safe and Easy Laser Liposuction
Allure medspa offer safe and easy laser liposuction. Known for their skill in liposuction procedures, Celebrity Cosmetic Surgeon Dr. Milan Doshi at Allure medspa offer laser liposuction surgery for men and women. Here, the most advanced lipolysis system is used for effective fat removal and body contouring. It is a revolutionary, minimally invasive laser liposuction treatment that destroys fat cells and helps tighten loose skin.
Liposuction Surgery for Precise Body Contouring Results
The technique delivers a new level of safety and efficiency. Cosmetic surgeons can target specific body areas that were inaccessible with traditional liposuction methods. High powered lasers and smaller liposuction Surgery cannulas enable more precise contouring and skin tightening.
There is a reason Dr. Doshi is considered in Mumbai, India's "Top Liposuction Surgeon" with a top-secret list of actors, models, and social elite, He is regularly operating many celebrities from Tollywood, Bollywood, NRIs, Foreigners on regular basis.
Areas can be treated such as:
- Chin
- Neck
- Jaw line
- Chests
- Breasts
- Thighs
- Hips
- Abdomen
- Love Handles
- Back of the upper arms etc.
Safe and Effective Liposuction device, offers benefits such as:
- More effective laser lipolysis
- Real, smooth results
- Proven tissue coagulation resulting in better skin tightening
- Targets only fat cells, muscle and nerve tissue remain intact
- Less pain, faster healing and minimal bruising
- Smaller incisions and less scarring
- Excellent contouring and visual improvement
"The best technology and highest standards of safety"
How much does liposuction cost?
For an estimate on how much liposuction cost Mumbai, we recommend that you call us on +91 98690 41559 Or Fill inquiry form so that we can contact you for the detailed discussion.


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*Reborns as 90% board games, 10% everything else, 5% lard, 15% not familiar with percentages.*
Wednesday, March 30, 2016
It's Not You, Kickstarter, It's Me
It's easy to claim that I just don't have the funds to put up front for Kickstarter projects, or even that a project doesn't appeal to me enough to contribute. For me, though, I feel it's deeper than that. I'm not sure what to say, other than I've grown out of Kickstarter. Or moreso, grown out of its marketing scheme.
Posted by Unknown at 4:50 PM 0 comments
Tuesday, March 29, 2016
I LOVE _______, A Segment Of Board Game Infatuation: Sylvion
There are A LOT of board game reviewers out there, and a lot of them employ very similar review styles - a quick overview of rules, final thoughts, verdict. That's all fine and good, and I have my own favorites in which ones to watch, but they all should be taken with an objective grain of salt. To me, reviews are only an aid to you and your own tastes. What is a treasure to them may not be a treasure to you, and it's important that you - yes, YOU - know what you like, or else you'll spiral into a never-ending money drain of what everyone else says you should enjoy.
Recently, I've re-assessed my board game purchase choices, boiling them down to one simple question: will I enjoy it? The same goes for the games currently in my collection because, obviously, I enjoy it in some form or another. But what, exactly, do I enjoy in each one that keeps me playing them? Each game in my collection has (or should have) that one spark that keeps calling to me, keeps me interested in bringing the game to the table. Here are some games that have that spark, and is usually the starting point in which I'd rattle on about why these games are my favorites. I've put them in a segment I like to call "I LOVE _______!"
[Please note - these are NOT REVIEWS; these are just reasons why I enjoy these games in my collection.]
[Please note - these are NOT REVIEWS; these are just reasons why I enjoy these games in my collection.]
Posted by Unknown at 8:14 AM 0 comments
Monday, March 28, 2016
A Blogging Test
Hello, folks!
Just thought I'd try something new here for a change. You see, this blog's been running for some time now (jeez, 2007??), and only recently has it mostly shifted gears towards board games. However, the lack of consistency is deteriorating, and it shows.
Posted by Unknown at 8:00 AM 0 comments
Tuesday, March 15, 2016
Sleeving Cards: My Story
Everyone has a different opinion on whether or not to sleeve or not sleeve cards in board games. There are some valid points made for either end, and I respect every one of them. Rather than writing an article that highlights all these thoughts and views, I want to write what sleeves mean to me. It's not as simple as you'd think.
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CEOs have come to recognize the importance of IT. Therefore, gone are the days where CIOs are confined to an IT room. New generation CIOs must be change agents and visionaries.
In a recent blog post, "The Voice of the Next Generation CIO," Soeren Jensen, the vice president of Enterprise Management and Software at Schneider Electric™, provides insights on the ever-evolving role of CIOs with video highlights from a panel discussion which took place at the CIO Summit Event, "Driving an Agenda for Business Success," organized in the Middle East by IDC.
The most important metric: customer satisfaction
CIOs are more than responsible for ensuring continuous backend operations for their enterprises, but also making sure that their customers are happy. And this requires a change in the way ROI for IT is measured.
During the panel discussion, Dr. Arwa Y. Al-Aama, vice mayor for IT affairs at Jeddah Municipality said that the CIO has become among the "three key people in an organization, internally and externally who deal with both the inside and outside world." Essentially the CIO for Jeddah Municipality, Dr. Al-Aama oversees the technological infrastructure, applications, network and communications, budgeting, and resource allocation.
As one of the most senior women working in the public sector in Saudi Arabia, Dr. Al-Aama has more than broken through the glass ceiling; she has also become an agent of change. At Jeddah Municipality, the balanced scorecard was flipped upside-down so that customer satisfaction became the most important metric for success, as opposed to financial value on ROI.
Keeping up with technology is just part of a CIO's job. Now they are under pressure to drive innovation as well, which requires listening to "internal customers" and delivering IT services that "empower them to change the world," said Dr. Al-Aama, referencing the important role technology played during the Arab Spring.


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About Reilly - We craft more than just windows and doors.
Welcome to Reilly Architectural. In 1981 I rented a large, unused chicken coop from a farmer in Bridgehampton and spent four weeks wielding shovel and pitch fork to create my first custom millwork and cabinetry shop. I had forsaken a career as an architect in favor of sawdust and the satisfaction of building things with my own hands, something that still gives me tremendous pleasure.
That was many shops and a mountain of sawdust ago. Now operating out of converted airplane hangars in Calverton with over 200 employees, the dedication and passion that moved me to build my first project thirty years ago remains a key component of our success today. State-of-the-art technology along with the skilled eyes and careful hands of master craftsmen who remain our lifeblood empower us to produce the highest quality windows, doors, screens shutters, millwork and cabinetry available anywhere in the world.
From the very beginning, our company's fine reputation and breadth of offerings has grown due to the beauty and superiority of our final product, a fact that has become our hallmark and a source of tremendous pride. The outcome of our commitment to excellence in everything we do is the fulfillment of your vision as the discerning customer. From all of us here at Reilly, that's our pledge, that's our promise – and you can count on it.
We pride ourselves on creativity and execution, along with being versed in millwork and cabintry in many different applications. When you have a challenging project that calls for full integration of the buildiung envelope with your millwork and cabinetry needs, please consider the years of experience that we can bring to bear to help deliver your vision to a stunning conclusion.View a conversation with Michael Reilly and Martha Stewart.


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Hi all!
While I usually write about comic conventions, there was a technical convention that I was lucky enough to attend this past week. I'll try not to get too much into the weeds on the various talks, but, if you're interested, message me, and we can talk about code and nerdiness.
Google holds an annual developers conference, known as I/O, every year. Link here. This year it was held at the Shoreline Amphitheater and surrounding area in Mountain View next to/on the Google campus. If you've never been, Google has streets of buildings for their campus. They have giant statues of Androids from every major release as well as random statues throughout the area. You see employees riding the multi-colored bicycles, the self-driving cars, and the giant place marker for the Maps team. It's quite impressive, especially when you think about how the work going on inside those buildings has shaped the world. In all fairness, you can probably say that about a lot of companies' headquarters in Silicon Valley. We have a lot going on here.
Anyway, on to the conference!
Day 1: The first day was a bit chaotic. It was incredibly warm (90+ degrees), and the area had little to no shade. 7000+ people packed into the Amphitheater to watch the keynote, which started at 10am sharp. We found some shade on the lawn and stayed there instead of our assigned seats, which were in the sun. Google is working on a ton of new things, and they were happy to showcase a lot of them.
- Google Home: While Amazon has Echo, Google is working on its own home companion that will allow you to listen to music, control your Nest and other integrated products, and answer questions for you. A bit Big Brother-ish, but it does help advance machine learning.
- Allo: Allo is a smart chat program that can learn from your usual responses and respond with smart suggestions to people. There are games you can play with it and your friends in chat, it's integrated with YouTube for video, and it even offers an incognito mode that deletes your chats once you are finished with them just like Chrome's incognito mode. Unclear if this is flat out replacing Hangouts, but I assume so.
- Duo: Google's new video calling service that uses your phone number for video chat. You have a live preview of the caller, which is semi-creepy. The guy demoing it hung up on his kids in front of millions, which was easily the funniest part of the keynote.
- Android N: There isn't a name for the new version yet, so you can vote for it here. This version will be integrated with Vulkan, has a lot of compiler adjustments to improve the runtime and reduce the amount of storage needed for an app. You'll be able to clear all notifications and double tap to go back to the previous app. There will also be picture-in-picture for Android TV.
- Daydream: With everyone doing VR, it makes sense that Google is as well. Daydream is their product. While it works somewhat with Cardboard, they have a plan to create a headset and a controller. It will work with Google Movies, street view in Maps, Google Photos, and YouTube.
- Android Watch: Designers are now creating nice watchbands, so they look more like watches and less hideous. New messaging, ability to write a reminder on the watch, and can track your fitness. Also, your phone doesn't have to be on for the watch to work.
- There were a lot of updates to Android Studio for devs, improved analytics to apps, and the open sourcing of part of the machine learning api's.
- Android Instant Apps: Possibly one of the coolest things from the keynote was the announcement that you can view something in an app without having to install it. For example, someone sends you a Buzzfeed link, and you don't have the app. You can open the link, which will open in the app but not actual install anything on your phone. You can have a great experience without bloating your phone.
After some craziness of trying to find food (too many people, not enough chicken), we settled in for the first breakout talk: Android N. The talks were held in pop-up domes around the area. As I mentioned earlier, there were a lot of changes/improvements in the newest version. Constraint layouts, new notif templates, split screen, easy multi-locale for international apps, ability to say exactly what you need access to in your permissions, and Vulkan support were some of the highlights.
Grayson and I split up at this point, and I went to the Games: The Google Advantage talk. There were several big things mentioned. First, there is a donations api that is being added for players to donate to favorite charities in game. It's an easy way to help the world. Second, Google is launching an Indie Corner, a section of the Play store that will focus only on Indie games and Indie developers. It's a great way to get your game out there, and you can submit your game to them here. Third, there are a ton of enhancements to the player stats. You can see all kinds of information about your app and figure out the best way to use that information. Fourth, they are introducing video recording and live streaming to YouTube. Twitch has a pretty good handle on this market, so I'm curious if Google will be able to penetrate it.
Next was a talk on Google Play, which was also somewhat games related. There is a new beta program that allows for private feedback and new ways to experiment with icons and descriptions to see which ones users really respond to. The Developer Console has enhanced benchmarks and reports, along with a mobile app. There will be an Early Access section in the Play store for early adopters and those apps that offer beta programs. The presenters also focused on how important it is to keep your app small as the majority of emerging markets have smaller capacity phones. They also went through the algorithms a bit for Play Search, Recommendations, and Top Charts to explain how your app description can impact your appearance in these.
The last talk of the day was on Vulkan. Vulkan is a new low-level graphics api that offers higher performance but requires you to know more of what you're doing. You have a lot of control over buffers and threads, and the presenter kept saying how easy it is to mess up. However, the rewards worth it as your games will run faster and perform better. This was a highly technical talk, so let me know if you want more details.
Day 2: The weather was cooler, although I was still sunburned from the first day. So, we spent more of the day exploring instead of panicking about talks we couldn't get into.
The first talk I went to was the Realtime Database using Firebase. Databases are what I have a lot of experience with in my real job. Firebase, which is a whole suite of products, offers a cloud database platform that handles synchronization and offline mode surprisingly well. It uses JSON and is really like a tree of lists and objects instead of the usual SQL tables that I work with.
Afterwards, I went to another Google Play talk, but it included most of the things I'd heard about in my previous Google Play talk. They went into instant apps a bit more and showed off some of the Firebase stats that are available for apps.
I attended a couple of VR/AR (virtual reality vs augmented reality) talks in the afternoon. First was the Daydream talk, where the team discussed challenges of VR and their plans/attempts at making a controller that was responsive and felt natural. It's kind of like a Wiimote with a circle touchpad at the top, which is quite different than the Oculus controllers. Also, #SpeakerTree. The second talk was around Project Tango, which is more computer vision. Grayson worked extensively with this in his Camerascript app, so I was more familiar with mapping the world around us. The new phone being developed by Lenovo will have the depth sensor needed to truly experience AR, and it's really impressive what can be done. The presenter demoed several cool AR app such as previewing furniture at size in your home to see how things would really look and a dinosaur experience where you can see them at full scale and explore. There are a lot of educational and fun opportunities available.
Day 3: Tired, sore, and exhausted, we headed back to Mountain View for a third day. While 90 on Wednesday, it was now in the upper 50s with a stiff wind. And I thought the weather in Texas was bipolar.
My first talk was on Machine Learning. As you know, I'm a huge sci-fi fan. Terminator: The Sarah Connor Chronicles was one of my favorite shows, and they actually spent a lot of time on this subject. Computers can already beat us at chess, so one was taught to play Go, a game that is considered incredibly intricate and strategic. The AI dominated, and the second game shocked the world. Read up on it if you haven't already. This talk was more of a discussion as the team said where they thought AI was going, the next problems they are trying to solve. They explained how medical and speech advancements are next, but they are still very limited. For example, they cannot transfer knowledge to another domain. The AI that plays Go cannot apply what it knows to anything else. Also, the system is a fixed size, so it cannot expand to learn more. When a system can translate English into English, we will enter the next phase of machine learning because the system will be able to understand context, emotion, and language at the level we do. It's fascinating stuff, and we have a long way to go before we create Skynet.
The next talk was back to games. Netmarble, the top Korean mobile game company, was there, explaining how they used tools and tips from the new stats to dominate the Asian market. Apparently, it's very difficult to port for Western audiences because Koreans spend 4-5 hours a day gaming on their phones, while we only spend 1-2 hours.
I attended a talk on RecycleViews, which was more for Grayson. They talked about the code changes in views and how they better handle animations, children, etc. The last talk I attended was on VR and Cinema. This talk by Jessica Brillhart was one of my favorites. She's one of Google's filmmakers and explained how the storytelling process changes for VR movies. She talked about frames, editing, and how it's about building a world, not stitching together single frames. You try to guide the viewer towards an experience and a story, but they don't have to follow your directions. You have to remind them that they can move around, turn to see the world. The viewer has to discover things for themselves, be the appropriate height, and have a human experience in order to truly enjoy the movie. She's made a ton of movies that she'll be posting to her YouTube channel. One of them star the creators of Myst, Robyn and Rand Miller. Fun fact: Myst is her favorite video game.
Well, I think this post has been long enough. Google I/O is a great experience. You spend three days learning and meeting fellow tech people. There's great food, parties, and a chance to try out new tech. It's a bit pricy, but something you never forget.
Thanks for making it to the end! Enjoy my photos!


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On Resources: My Rationale Explained
Confused About Email Marketing? These Tips Can Help Email marketing is one of the most innovative ways that you Can advertise your wares to people that are very likely to buy them. It will, however, take some know-how to build an effective email list. This report will show you some things you can do that will help you be successful with email advertising. Be certain of all the colors you use in your email are impartial. If colors are too bland, the customer may not wish to read the article. On the other hand, if the colors are too bright, it could frustrate the reader. Try to stick with neutral colors, like black, grey, and white. Add a link to a subscription type into Your Advertising newsletters. That way, if your clients forward marketing emails to their friends, their friends can easily subscribe to a list also. Utilizing this technique makes it easy for you to build a large collection of possible clients who have agreed to receive your advertising emails.
The Essential Laws of Emails Explained
Steer clear of leasing or buying lists to mat your email marketing database. Not only do you not know if the emails you've bought are truly your target market, but the lists can actually hurt your deliver-ability rates and finally your standing. As much as you can, build your record organically.
The 9 Most Unanswered Questions about Options
Provide subscribers with a method out. Place an "unsubscribe" link in your emails or on your website to allow them to remove themselves from your list. You should also set your list up to cull itself by eliminating subscribers after a particular amount of messages prompt no response or action in the recipient. This prevents your mails from becoming annoying to disinterested readers and preserves your picture. Be predictable in your mails. Send them on a specific schedule. Ensure that you send something at least a month, this can help retain your customers interested. If you're able to send mails on or two times every week, that's even better. Test out that days give your website the best answers, and then apply these times as your regular days to send mails. Don't over send emails to your subscribers. Your customers Often will get several messages a day and are extremely busy in their own lives. If you send a lot of daily emails, readers are more likely to trash them without actually reading the content that you place so much time to. Do a little testing to see how your readers respond to your mailing schedule and frequency. Your email advertising campaign will probably be more effective if you make it simple for clients to unsubscribe. This might appear paradoxical, but Individuals will have a tendency to trust you more if you make them feel as though they are in control. article the unsubscribe link in an obvious location so that they can find it easily.


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Stent mounting device and a method of using the same to coat a stent
A stent mounting device and a method of coating a stent using the device are provided.
Latest Advanced Cardiovascular Systems, Inc. Patents:
1. Field of the Invention
This invention relates to a stent mounting device and a method of coating a stent using the device.
2. Description of the Background
Blood vessel occlusions are commonly treated by mechanically enhancing blood flow in the affected vessels, such as by employing a stent. Stents act as scaffoldings, functioning to physically hold open and, if desired, to expand the wall of the passageway. Typically stents are capable of being compressed, so that they can be inserted through small lumens via catheters, and then expanded to a larger diameter once they are at the desired location. Examples in the patent literature disclosing stents include U.S. Pat. No. 4,733,665 issued to Palmaz, U.S. Pat. No. 4,800,882 issued to Gianturco, and U.S. Pat. No. 4,886,062 issued to Wiktor.
FIG. 1 illustrates a conventional stent 10 formed from a plurality of struts 12. The plurality of struts 12 are radially expandable and interconnected by connecting elements 14 that are disposed between adjacent struts 12, leaving lateral openings or gaps 16 between adjacent struts 12. Struts 12 and connecting elements 14 define a tubular stent body having an outer, tissue-contacting surface and an inner surface. Struts 12 that are located at the respective ends of the tubular stent body are referred to herein as end rings 18.
Stents are used not only for mechanical intervention but also as vehicles for providing biological therapy. Biological therapy can be achieved by medicating the stents. Medicated stents provide for the local administration of a therapeutic substance at the diseased site. Local delivery of a therapeutic substance is a preferred method of treatment because the substance is concentrated at a specific site and thus smaller total levels of medication can be administered in comparison to systemic dosages that often produce adverse or even toxic side effects for the patient.
One method of medicating a stent involves the use of a polymeric carrier coated onto the surface of the stent. A composition including a solvent, a polymer dissolved in the solvent, and a therapeutic substance dispersed in the blend is applied to the stent by immersing the stent in the composition or by spraying the composition onto the stent. The solvent is allowed to evaporate, leaving on the stent strut surfaces a coating of the polymer and the therapeutic substance impregnated in the polymer.
A shortcoming of the above-described method of medicating a stent is the potential for coating defects. While some coating defects can be minimized by adjusting the coating parameters, other defects occur due to the nature of the interface between the stent and the apparatus on which the stent is supported during the coating process. A high degree of surface contact between the stent and the supporting apparatus can provide regions in which the liquid composition can flow, wick, and collect as the composition is applied. As the solvent evaporates, the excess composition hardens to form excess coating on or between the stent struts. Upon the removal of the coated stent from the supporting apparatus, the excess coating may stick to the apparatus, thereby removing some of the coating from the stent and leaving bare areas. Alternatively, the excess coating may stick to the stent, thereby leaving excess coating as clumps or pools on the struts or webbing between the struts.
Thus, it is desirable to minimize the interface between the stent and the apparatus supporting the stent during the coating process to minimize coating defects. Accordingly, the present invention provides for a device for supporting a stent during the coating application process. The invention also provides for a method of coating the stent supported by the device.SUMMARY OF THE INVENTION
The present invention provides a device for supporting a stent during the application of a coating to the stent. The method includes a body configured to penetrate at least partially into the stent and members protruding out from the body for preventing any contact between the inner surface of the stent and the outer surface of the body. The members can be arranged about the circumference of the body and can be circular in shape. In one embodiment, the device additionally includes slots in the outer surface of the body for receiving some of the coating material that comes into contact with the body.
Also provided is a mandrel for supporting a stent. The mandrel includes a body for being at least partially inserted in a hollow body of a stent. The mandrel also includes at least two members projecting out of the body and capable of being in contact with the inner surface of the stent. In one embodiment, the mandrel additionally includes grooves positioned in the body for receiving and containing excess coating substance applied to the stent.
The present invention also provides a method of coating a stent. The method includes positioning a stent over a mandrel having members projecting out of the mandrel, wherein at least one of the members is in contact with the inner surface of the stent. The method also includes applying a coating material to the stent.BRIEF DESCRIPTION OF THE FIGURES
FIG. 1 illustrates a conventional stent.
FIG. 2 illustrates a mounting assembly for supporting a stent.
FIG. 3 illustrates the interface of the spines with the stent.
FIG. 4A illustrates the mandrel of the mounting assembly, illustrating the spines and the optional grooves thereon in accordance with embodiments of the present invention.
FIG. 4B is a perspective view of the mandrel in FIG. 4A.
FIG. 5 is an end view of the spines-stent interface in FIG. 3.DETAILED DESCRIPTION Embodiments of the Stent Mounting Assembly
Referring to FIG. 2, a mounting assembly 20 for supporting stent 10 is illustrated to include a support member 22 and a mandrel 24. Support member 22 can connect to a motor 26A so as to provide rotational motion about the longitudinal axis of stent 10, as depicted by arrow 28, during the coating process. Another motor 26B can also be provided for moving support member 22 in a linear direction, back and forth, along a rail 30. In accordance with one embodiment, mandrel 24 can be permanently affixed to support member 22. In accordance with another embodiment, support member 22 can include a bore 32 for receiving a first end 34 of mandrel 24. Bore 32 should be deep enough to allow mandrel 24 to securely mate with support member 22 so as to prevent movement of stent 10 on mounting assembly 20. First end 34 of mandrel 24 can be threaded so as to screw into bore 32 of support member 22.
As depicted in FIGS. 2 and 3, mounting assembly 20 supports stent 10 via protrusions or spines 36 disposed on mandrel 24, so as to provide a space between the outer surface of mandrel 24 and the inner surface of stent 10. Spines 36 are shown in greater detail in FIGS. 4A and 4B. Spines 36 can be made of any suitable material, and are typically made of the same material as mandrel 24. Examples of such suitable materials include stainless steel and polytetrafluoroethylene (e.g., TEFLON). While spines 36 are depicted herein as having a curved or semi-circular shape, spines 36 can be custom shaped to suit stents of various types. The shape of spines 36 can affect the retention of stent 10 on mandrel 24, the ease with which stent. 10 can be mounted and dismounted, and the degree of surface contact with stent 10. Sharp, pointed, and/or angular spines 36 can provide for a reduction in potential coating defects by providing a very small surface area at which stent 10 is in physical contact with spines 36. However, sharp, pointed, and/or angular spines 36 can snag struts 12, making mounting and dismounting of stent 10 more difficult. Spines 36 can be of any suitable size depending on the dimensions of the particular stent 10 to be supported. By way of example, to support stent 10 having a length of about 0.315 inches (about 8 mm) and an unexpanded internal diameter of about 0.035 inches (about 0.889 mm), which has been expanded to about 0.075 inches (about 1.905 mm) on mandrel 24 (having an outer diameter of 0.040 inches (about 1.016 mm)), spines 36 can have a width w from about 0.005 inches to about 0.007 inches (about 0.127 mm to about 0.178 mm) and a height h of about 0.017 inches (about 0.432 mm).
Mandrel 24 can have any suitable number of sets of spines 36. Each set of spines 36 can include any suitable number of individual spines 36. The.particular number of sets, number of spines 36 within each set, arrangement of spines 36, distance between the sets, and distance between individual spines 36 in each set depend on the design of stent 10 to be supported. For example, if two sets of spines 36 are used to support stent 10 with a length of about 0.315 inches (about 8 mm), the distance between each set can be about 0.318 inches (about 8.1 mm).
In accordance with another embodiment, mounting assembly 10 can include grooves 38. Grooves 38 function to draw excess coating material away from stent 10 during the coating process, thereby further reducing the potential for pooling and other coating defects due to the excess coating material. Grooves 38 can be disposed between spines 36 and/or along the length of mandrel 24. Grooves 38 can be of any suitable length lg as shown in FIG. 4A, any suitable depth dg as shown in FIG. 5, and any suitable shape to facilitate receipt and containment of the excess coating material. By way of example, grooves 38 can have length lg from about 0.005 inches to about 1.5 inches (0.127 mm to about 38.1 mm) and depth dg from about 0.001 inches to about 0.002 inches (0.025 mm to about 0.051 mm).Coating a Stent Using the Stent Mounting Assembly
The following method of application is being provided by way of illustration and is not intended to limit the embodiments of mounting assembly 20 of the present invention. By way of illustration, a spray apparatus, such as EFD 780S spray device with VALVEMATE 7040 control system (manufactured by EFD Inc., East Providence, R.I.), can be used to apply a composition to stent 10. EFD 780S spray device is an air-assisted external mixing atomizer. The composition is atomized into small droplets by air and uniformly applied to the stent surfaces. The atomization pressure can be maintained at a range of about 5 psi to about 20 psi. The droplet size depends on such factors as viscosity of the solution, surface tension of the solvent, and atomization pressure. Other types of spray applicators, including air-assisted internal mixing atomizers and ultrasonic applicators, can also be used for the application of the composition.
During the application of the composition, stent 10 supported by mounting assembly 20 can be rotated about the stent's central longitudinal axis. Rotation of stent 10 can be from about 1 rpm to about 300 rpm, more narrowly from about 50 rpm to about 150 rpm. By way of example, stent 10 can rotate at about 120 rpm. Stent 10 can also be moved in a linear direction along the same axis. Stent 10 can be moved at about 1 mm/second to about 12 mm/second, for example about 6 mm/second, or for a minimum of at least two passes (i.e., back and forth past the spray nozzle). The flow rate of the solution from the spray nozzle can be from about 0.01 mg/second to about 1.0 mg/second, more narrowly about 0.1 mg/second. Multiple repetitions for applying the composition can be performed, wherein each repetition can be, for example, about 1 second to about 10 seconds in duration. The amount of coating applied by each repetition can be about 0.1 micrograms/cm2 (of stent surface) to about 10 micrograms/cm2, for example less than about 2 micrograms/cm2 per 5-second spray.
Each repetition can be followed by removal of a significant amount of the solvent(s). Depending on the volatility of the particular solvent employed, the solvent can evaporate essentially upon contact with stent 10. Alternatively, removal of the solvent can be induced by baking stent 10 in an oven at a mild temperature (e.g., 60° C.) for a suitable duration of time (e.g., 2-4 hours) or by the application of warm air. The application of warm air between each repetition prevents coating defects and minimizes interaction between the active agent and the solvent. The temperature of the warm air can be from about 30° C. to about 60° C., more narrowly from about 40° C. to about 50° C. The flow rate of the warm air can be from about 20 cubic feet/minute (CFM) (0.57 cubic meters/minute (CMM)) to about 80 CFM (2.27 CMM), more narrowly about 30 CFM (0.85 CMM) to about 40 CFM (1.13 CMM). The warm air can be applied for about 3 seconds to about 60 seconds, more narrowly for about 10 seconds to about 20 seconds. By way of example, warm air applications can be performed at a temperature of about 50° C., at a flow rate of about 40 CFM, and for about 10 seconds. Any suitable number of repetitions of applying the composition followed by removing the solvent(s) can be performed to form a coating of a desired thickness or weight. Excessive application of the polymer can, however, cause coating defects.
Operations such as wiping, centrifugation, or other web clearing acts can also be performed to achieve a more uniform coating. Briefly, wiping refers to the physical removal of excess coating from the surface of stent 10; and centrifugation refers to rapid rotation of stent 10 about an axis of rotation. The excess coating can also be vacuumed off of the surface of stent 10.
In accordance with one embodiment, stent 10 can be at least partially pre-expanded prior to the application of the composition. For example, stent 10 can be radially expanded about 20% to about 115%, for example about 112%—the measurement being taken from the stent's inner diameter at an expanded position as compared to the inner diameter at the unexpanded position. The expansion of stent 10, for increasing the interspace between stent struts 12 during the application of the composition, can further prevent "cob web" formation between the stent struts 12.
In accordance with one embodiment, the composition can include a solvent and a polymer dissolved in the solvent and optionally a wetting fluid. The composition can also include active agents, radiopaque elements, or radioactive isotopes. Representative examples of polymers that can be used to coat stent 10 include ethylene vinyl alcohol copolymer (commonly known by the generic name EVOH or by the trade name EVAL), poly(hydroxyvalerate); poly(L-lactic acid); polycaprolactone; poly(lactide-co-glycolide); poly(hydroxybutyrate); poly(hydroxybutyrate-co-valerate); polydioxanone; polyorthoester; polyanhydride; poly(glycolic acid); poly(D,L-lactic acid); poly(glycolic acid-co-trimethylene carbonate); polyphosphoester; polyphosphoester urethane; poly(amino acids); cyanoacrylates; poly(trimethylene carbonate); poly(iminocarbonate); copoly(ether-esters) (e.g. PEO/PLA); polyalkylene oxalates; polyphosphazenes; biomolecules, such as fibrin, fibrinogen, cellulose, starch, collagen and hyaluronic acid; polyurethanes; silicones; polyesters; polyolefins; polyisobutylene and ethylene-alphaolefin copolymers; acrylic polymers and copolymers; vinyl halide polymers and copolymers, such as polyvinyl chloride; polyvinyl ethers, such as polyvinyl methyl ether; polyvinylidene halides, such as polyvinylidene fluoride and polyvinylidene chloride; polyacrylonitrile; polyvinyl ketones; polyvinyl aromatics, such as polystyrene; polyvinyl esters, such as polyvinyl acetate; copolymers of vinyl monomers with each other and olefins, such as ethylene-methyl methacrylate copolymers, acrylonitrile-styrene copolymers, ABS resins, and ethylene-vinyl acetate copolymers; polyamides, such as Nylon 66 and polycaprolactam; alkyd resins; polycarbonates; polyoxymethylenes; polyimides; polyethers; epoxy resins; polyurethanes; rayon; rayon-triacetate; cellulose; cellulose acetate; cellulose butyrate; cellulose acetate butyrate; cellophane; cellulose nitrate; cellulose propionate; cellulose ethers; and carboxymethyl cellulose.
"Solvent" is defined as a liquid substance or composition that is compatible with the polymer and is capable of dissolving the polymer at the concentration desired in the composition. Examples of solvents include, but are not limited to, dimethylsulfoxide (DMSO), chloroform, acetone, water (buffered saline), xylene, methanol, ethanol, 1-propanol, tetrahydrofuran, 1-butanone, dimethylformamide, dimethylacetamide, cyclohexanone, ethyl acetate, methylethylketone, propylene glycol monomethylether, isopropanol, isopropanol admixed with water, N-methyl pyrrolidinone, toluene, and combinations thereof.
The active agent can be for inhibiting the activity of vascular smooth muscle cells. More specifically, the active agent can be aimed at inhibiting abnormal or inappropriate migration and/or proliferation of smooth muscle cells for the inhibition of restenosis. The active agent can also include any substance capable of exerting a therapeutic or prophylactic effect in the practice of the present invention. For example, the agent can be for enhancing wound healing in a vascular site or improving the structural and elastic properties of the vascular site. Examples of agents include antiproliferative substances such as actinomycin D, or derivatives and analogs thereof (manufactured by Sigma-Aldrich 1001 West Saint Paul Avenue, Milwaukee, Wis. 53233; or COSMEGEN available from Merck). Synonyms of actinomycin D include dactinomycin, actinomycin IV, actinomycin I1, actinomycin X1, and actinomycin C1. The active agent can also fall under the genus of antineoplastic, antiinflammatory, antiplatelet, anticoagulant, antifibrin, antithrombin, antimitotic, antibiotic, antiallergic and antioxidant substances. Examples of such antineoplastics and/or antimitotics include paclitaxel (e.g. TAXOL® by Bristol-Myers Squibb Co., Stamford, Conn.), docetaxel (e.g. Taxotere®, from Aventis S.A., Frankfurt, Germany) methotrexate, azathioprine, vincristine, vinblastine, fluorouracil, doxorubicin hydrochloride (e.g. Adriamycin® from Pharmacia & Upjohn, Peapack N.J.), and mitomycin (e.g. Mutamycin® from Bristol-Myers Squibb Co., Stamford, Conn.) Examples of such antiplatelets, anticoagulants, antifibrin, and antithrombins include sodium heparin, low molecular weight heparins, heparinoids, hirudin, argatroban, forskolin, vapiprost, prostacyclin and prostacyclin analogues, dextran, D-phe-pro-arg-chloromethylketone (synthetic antithrombin), dipyridamole, glycoprotein IIb/IIIa platelet membrane receptor antagonist antibody, recombinant hirudin, and thrombin inhibitors such as Angiomax™ (Biogen, Inc., Cambridge, Mass.) Examples of such cytostatic or antiproliferative agents include angiopeptin, angiotensin converting enzyme inhibitors such as captopril (e.g. Capoten® and Capozide® from Bristol-Myers Squibb Co., Stamford, Conn.), cilazapril or lisinopril (e.g. Prinivil® and Prinzide® from Merck & Co., Inc., Whitehouse Station, N.J.); calcium channel blockers (such as nifedipine), colchicine, fibroblast growth factor (FGF) antagonists, fish oil (omega 3-fatty acid), histamine antagonists, lovastatin (an inhibitor of HMG-CoA reductase, a cholesterol lowering drug, brand name Mevacor® from Merck & Co., Inc., Whitehouse Station, N.J.), monoclonal antibodies (such as those specific for Platelet-Derived Growth Factor (PDGF) receptors), nitroprusside, phosphodiesterase inhibitors, prostaglandin inhibitors, suramin, serotonin blockers, steroids, thioprotease inhibitors, triazolopyrimidine (a PDGF antagonist), and nitric oxide. An example of an antiallergic agent is permirolast potassium. Other therapeutic substances or agents which may be appropriate include alpha-interferon, genetically engineered epithelial cells, rapamycin and dexamethasone.
Examples of radiopaque elements include, but are not limited to, gold, tantalum, and platinum. An example of a radioactive isotope is p32. Sufficient amounts of such substances may be dispersed in the composition such that the substances are not present in the composition as agglomerates or flocs.
While particular embodiments of the present invention have been shown and described, it will be obvious to those skilled in the art that changes and modifications can be made without departing from this invention in its broader aspects. Therefore, the appended claims are to encompass within their scope all such changes and modifications as fall within the true spirit and scope of this invention.
1. A device for supporting a stent during the application of a coating material to the stent, comprising:
- body configured to penetrate at least partially into the stent; and
- members protruding out from the body for preventing any contact between an inner surface of the stent and an outer surface of the body.
2. The device of claim 1, additionally including slots in the outer surface of the body for receiving some of the coating material that comes into contact with the body.
3. The device of claim 1, wherein the members are arranged about a circumference of the body.
4. The device of claim 1, wherein the members are circular in shape.
5. A mandrel for supporting a stent, comprising:
- a body for being at least partially inserted in a hollow body of a stent;
- at least two members projecting out of the body and capable of being in contact with an inner surface of the stent.
6. The mandrel of claim 5, wherein the at least two members are circular in shape.
7. The mandrel of claim 5, wherein a surface of the body does not contact the inner surface of the stent.
8. The mandrel of claim 5, additionally including grooves positioned in the body for receiving and containing excess coating substance applied to the stent.
9. A method of coating a stent, comprising:
- positioning a stent over a mandrel having members projecting out of the mandrel, wherein at least one of the members is in contact with an inner surface of the stent; and
- applying a coating material to the stent.
10. The method of claim 9, additionally including rotating the stent about a longitudinal axis of the stent.
11. The method of claim 9, wherein the act of applying comprises spraying a polymer added to a fluid, and optionally including an active agent, onto the stent.
12. The method of claim 11, wherein the active agent is for the management of restenosis.
13. The device of claim 1, wherein the members protruding out from the body are curved in shape.
14. The device of claim 1, wherein the members protruding out from the body comprise individual protruding members.
15. The device of claim 1, wherein the body and the members protruding out from the body are fabricated from stainless steel.
16. The device of claim 1, wherein the body and the members protruding out from the body are fabricated from polytetrafluoroethylene.
17. The device of claim 2, wherein the slots are disposed between the members protruding out from the body.
18. The device of claim 17, wherein the slots extend along the length of the body.
19. The device of claim 1, wherein the body comprises a threaded first end.
20. The device of claim 19, wherein the threaded first end of the body screws into a bore in a support member.
21. A method of coating a stent, the method comprising the steps of:
- inserting a body at least partially into a stent, wherein the body includes members protruding therefrom for preventing any contact between an inner surface of the stent and an outer surface of the body; and
- applying a coating material to the stent.
22. The method of claim 21, wherein the step of inserting the body comprises inserting a mandrel at least partially into the stent.
23. The method of claim 21, wherein the step of applying a coating material comprises spraying a polymer, added to a fluid, and optionally including an active agent, onto the stent.
24. The method of claim 21, further comprising rotating the stent about the longitudinal axis of the stent.
|March 29, 1988
|January 31, 1989
|December 12, 1989
|August 4, 1998
|April 20, 1999
|April 27, 1999
|July 13, 1999
|January 4, 2000
|September 19, 2000
|Yang et al.
|November 28, 2000
|Hossainy et al.
|July 10, 2001
|Yang et al.
|November 27, 2001
|Zhong et al.
|April 2, 2002
|Tseng et al.
|May 14, 2002
- Plaridel K. Villareal, A Stent Mounting Device And A Method Of Using The Same To Coat A Stent, May 31, 2001, Ser. No. 09/873,020.
- Inventor: Plaridel K. Villareal; Application Ser. No.: 09/873,020; Filed May 31, 2001; Title: A Stent Mounting Device And A Method Of Using The Same To Coat A Stent.
Type: Grant
Filed: Jun 27, 2001
Date of Patent: Jun 3, 2003
Assignee: Advanced Cardiovascular Systems, Inc. (Santa Clara, CA)
Inventor: Mohammed E. Moein (San Jose, CA)
Primary Examiner: Gloria M. Hale
Attorney, Agent or Law Firm: Squire, Sanders & Dempsey, L.L.P.
Application Number: 09/894,242
International Classification: A61F/206;


text:
I recently got this in hardcopy, and was happy to review it here as well. I should note up front that I've never read the Mistborn series and honestly don't really read that much fantasy. So I came into it as an experienced roleplayer but a complete Mistborn noob.
The system presented is a solid system using six sided dice, similar to the classic d6 system from West End Games, though with some updated material to assist in improvisation and encourage players to use descriptions and environments for dynamic, vivid play. Characters roll a set of d6s and sum the result, trying to beat a target number. It gets the job done.
The setting is described succinctly and evocatively in a chapter or two, with a few more more dedicated to the magic system of the setting, which is unique. Magic in this world is connected to different sorts of metal and they have unique properties.
For example, one sort of magical effect permits people to offload their memories into magical pieces of copper, for later recall. What's important about these effects is that they are expansively detailed not necessarily in their capacities, but in how they've impacted the setting. What does it mean when a mage literally can carry a library in his pocket - what kind of personality would it create to know nothing until they need to know it? (No smart remarks about smartphones and wikipedia apps.)
Characters are part of a "crew", with a shared agenda, from the beginning. This selection helps games find direction, which is definitely needed in a fantasy world that you might not know anything about.
The ultimate test of a "new fantasy world" RPG for me is whether I want to play it, and the answer is yes, yes, I really, really do. This game makes me want to play a Mistborn game right away.
Because of the compelling, clear setting, the unique magical materials and the solid, well-explained system, I'm giving this game my highest marks.


text:
As indicated by the subtitle, "The Life and Times of Jesus of Nazareth," this book titled The Zealot is about the historical Jesus. But the reader will probably be disappointed to learn that most of that history comes from the Gospels in the New Testament. Only small bits and pieces of information come from non-Christian history. The author Reza Aslin, however, often relies on non-Christian history to point out statements in the Gospels that are false or inaccurate.
The title of The Zealot comes from a group of Jews who resisted Roman rule of Palestine. Aslin believes Jesus was one in a long line Jewish Zealots. Like many other of the Zealots, the Romans executed Jesus for his sedition. Crucifixion was a type of execution primarily reserved for rebels. What set Jesus apart from these other rebels was not his life, but rather his death. None of the other Zealots were resurrected, yet several of Jesus's disciples and apostles swore that they saw the resurrected Jesus and refused to retract their statements even unto death.
Incidentally, Aslin suggests that (a) John the Baptist was more of a mentor to Jesus than the current Catholic Church is willing to concede, (b) Apostle Paul was more of an outlier and a minor figure in the Church during his life, but after his death he became more prominent because his Gospels better fit the message that the Church was trying to sell, and (c) Jesus's brother James was actually bigger than Peter or Paul in developing the Church following Jesus's death.
The Zealot is an excellent primer for someone wanting some basic information about the conception of the Catholic Church.


text:
I have listed a new property at 9770 FENIAK ST in Chilliwack.
Nice sized home on a big corner lot, fenced backyard for pets and kids and walking distance to the park. Recent updates include new bathroom and paint in pleasing neutral colors. It comes with a 22x20 double car garage with 220 wiring for a shop or working on the car/truck. There are two bedrooms up and 3 nice sized rooms used bedrooms down below along with a family/rec room.


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Australia's Jake Stein false starts twice in decathlon 100m
You are forgiven a false start in the decathlon, unlike the regular sprints … but not two.
Jake Stein fumbled at the worst moment. On the blocks for the 100 metres, the first of his 10 events, the decathlete false-started twice in a row. Afterwards he could not believe he had committed such a schoolboy error - in fact, he could not remember having false starting since he was a child.
Stein's false starts:
"I just went a bit too early - twice - just school boy errors really," Stein said. "You learn to start when you are seven or eight and I forgot how to do it today.
"I tried to stay on my heels, it is the biggest crowd I have ever competed in front of, I kind of felt that I had heard a few things - the bloke on my inside was a bit loud and it could have just been him breathing - there were a few nerves being my first senior comp, I got a bit too excited and went twice."
The first false start was a close thing but after the athletes lowered to the blocks again the second nervous start was, even to the naked eye, a clear break.
Stein knew instantly it was him. He had that sinking feeling and immediately punched the ground in disgust. He knew he was quick - but not that quick.
"I definitely knew it was me, the guys I am competing against, I don't think they are silly enough to go twice," he said. "I knew it was me straight away, I could see I was well ahead of everyone - my start is not that good."
Without points from the sprint, the chances for the rising star of Australian athletics to take a medal here are gone.
The former world youth championships gold medallist and silver medallist in the world juniors a year later had been in the frame for a medal, but not now. He naturally contemplated abandoning competition immediately but quickly decided to carry on in the remaining events.
"For a couple of seconds I was like, 'Do I really want to be here?' And then my mind changed pretty quickly, 'Yes I do - this is what I have trained for for two years'; I wanted to get back out on the track, being inside that stadium is ridiculous, [there are] 40,000 people for [the] decathlon.
"Decathlon is 10 events, not nine, not one. I have got eight events now after the long jump. I am looking forward to those. I have got a few throws to show them how Australians compete.
"I felt decent in training. I usually compete well over the whole 10 events at major champs so I don't come here to go away without something to take from it. A medal was definitely in the plan, now it is just keep ticking away, get a few PBs and a few individual wins - three throws, three victories: that would be nice."


text:
|The attractive wife, the big house and the Beemer aren't enough for stockbroker M. Vincent — he needs a secret life, too.
Addicted to his nocturnal fantasies, he doesn't notice his wife, Sarah, quietly weaving a web of her own.
M. Vincent's secretary, Patty — so hungry for what she doesn't have — pretends to play his game until she makes a reckless move and the game turns ugly.
Then there is Robert, the manager from hell. He knows Vincent and Patty are up to something and he's not afraid to crack a few heads to find out what it is.


text:
Wedding backdrops are one trend this year that we are 100%
on board with. Not only can backdrops be used to cover unsightly walls, they
can add accent and texture to a room with minimal cost.
We absolutely love this white backdrop that we have
available this year:
We love that it is elegant, but can be combined with other
elements or even DIY projects to make it more personal. We love how it looks on
its own, but for a little more flavor, here are a couple of our favorite idea...


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How many other people will there be onboard?
On our RYA courses we have up to five students per instructor..
For our sailing trips we have up to six people onboard plus skipper and volunteer first mate.
We can have up to ten people onboard for group activities.
Where do we sleep? Do we go back to the marina each night?
We all sleep onboard, with a berth allocated to you. We usually stay in a different place each night, which could be at anchor or mooring in a marina with walk ashore access to showers and toilets. Please Note: The saloon is classed as a sleeping area. Exact sleeping arrangements are worked out with your skipper at the start of your course or trip depending on the mix of crew.
Can I arrive the night before to help with travel costs/travel time?
There is a range of accommodation available at Itchenor Sailing Club, ranging from £22/night bunk beds to ensuite rooms. They also have a good kitchen serving meals and breakfasts and are very helpful. Please mention Sail Boat Project when you enquire or book.
Do we eat onboard? Do you cater for special diets?
All meals and snacks are included in our rates and our vessels are well stocked for your time onboard. We provide vegetarian and vegan food by default as part of our commitment to lowering our company's carbon footprint, although please feel free to eat anything you want ashore. Thanks to our partners at Infinity Foods we have plenty of great snacks and ingredients. While we all take turns making meals, there are always some homemade pre-prepared dishes so you can make the most of your sailing and learning time. Please let us know about any other dietary needs – we are pretty familiar with various allergies and diets.
"The food really exceeded my expectations. I was pleased about your food policy beforehand but the reality of it was great. We managed to knock up some really nice dinners on board. We just couldn't make it though all of the biscuits though."
Is there a toilet onboard?
Each of our vessels are equipped with at least one sea toilet, called a 'heads', and by boat standards they are quite roomy, with washbasins. They have a slight knack to using them, which your skipper will show you, but they are pretty similar to a home flush toilet. We do ask you to use toilets ashore when in a marina.
Do you provide waterproofs?
Yes, we provide salapette trousers and jackets which are wind and waterproof, as well as sailing boots which provide a secure grip on deck. Please feel free to bring your own gear or to ask us for advice on where to purchase affordable sailing gear. Lifejackets and safety harnesses are provided.
Will it be rough, what if I feel sick?
Due to where our vessels are moored, the first days' sailing you will experience will be in sheltered waters, and we'll stay in such waters for entry and beginner levels. We want you to enjoy your sailing and our skippers remain very aware of how people are feeling and do their best to avoid unnecessarily unpleasant conditions by planning ahead.
What if the weather is really bad, what weather don't we go out in?
Sailing is obviously very weather dependent. We reserve the right to cancel trips and courses at our discretion, due to adverse weather. If we are forced to do so, we will be in touch with you in the days beforehand to advise and we will work with you to attempt to find you a suitable replacement or if not we will refund all of your money. However, Sail Boat Project cannot be held responsible for any other loss that you may have incurred due to cancellation of your course or trip. The final decision on whether a course or trip goes ahead is always based on the capabilities of those onboard and we are not interested in forcing anyone into being forced into a position they are uncomfortable with.
Will I get a certificate?
All the RYA practical and theory courses we deliver lead to a nationally recognised qualification within the RYA's sail cruising scheme, if you have met the syllabus requirements. We also issue certificate sof achievement as part of the RYA Sailability scheme and we have our own certificates of achievement for groups.
Do you make arrangements for people with special needs, learning or physical?
Yes, we have experience of taking people out sailing with a range of different needs. Our ethos is to make things possible and we will always work with you to allow inclusion and participation from everyone. While our vessels are not specifically adapted, for example for wheelchair users, we will always think about what changes we can make to get people out on the water. We use a variety of learning materials that engage and include people and our skippers and instructors are always learning and sharing with each other techniques to help people make the most of their time with us. Please feel free to discuss your needs with us. We are happy to meet up with you in advance, including onboard the vessel you will be sailing on to help you orientate and plan your sailing.
Can I talk to an instructor or skipper in advance?
Yes, if we can't put you through to one of our instructors or skippers when you call the office, we will pass on you details and have someone get back to you as soon as possible to have a chat with you.
Do you allow alcohol onboard?
Yes we do, in moderation! We may share a bottle of wine onboard or visit a pub during a course or trip, but please remember alcohol and getting used to the motion of the sea don't mix well.
Should I bring my log book?
Yes, if you have a sailing log book this is really good to bring along. For courses it will outline your syllabus, help your instructor see what experience you have and you can get it signed off at the end. For sailing trips you can record the nautical miles sailed and treat it as a mile builder towards any examinations you go for. They are also a useful record for your own interest. We always have log books available for sale onboard for £6.
Is it all sailing, is there time to explore places we visit?
Depending on the level of course you are on, there is usually time to explore a couple of the places we visit. The Competent Crew course includes using a dinghy, so you'll be able to explore from the water! On our sailing trips part of the idea is to have a look around sowewhere new. We usually agree as a group when to have time ashore as we always need to work around the weather and tides. If you have any particular requests make sure you let your skipper know.
Will I see any wildlife?
Plenty of birdlife and the odd seal – in Chichester harbour there is a whole seal colony at certain times of the year. Marine mammals are not as abundant as we'd like them to be, although porpoises in Poole Bay and dolphins off Chichester bar have been recent sightings. If we are lucky enough to be in the right place at the right time we would never move in close or cause any undue stress. We have marine wildlife spotter guides onboard to help you prepare.