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There are three bodies responsible for transport in the cell including the endoplasmic reticulum, the vesicles and the cell membrane. The endoplasmic reticulum moves materials within the cell body, while the vesicles move proteins to the cell membrane, and the membrane transports materials in and out of the cell.
While the endoplasmic reticulum's primary function is transportation, vesicles are also responsible for storing and moving proteins created in the Golgi body to the cell membrane. The cell membrane transports materials into and out of the cell both actively and passively. For example, water is passively transported into the cell by the cell membrane.

subset: commoncrawl


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The MSI GE620DX-278US is a Core i7-equipped desktop replacement laptop, designed to provide entertainment on the go, with features for both multimedia and gaming. With a quad-core processor, discrete graphics processing and a healthy selection of ports and connections, the MSI GE620DX-278US provides a similarly priced alternative to our desktop replacement Editors' Choice, the Samsung Series 7 (NP700Z5A-S03) ($1,299 list, 4 stars).
The MSI GE620DX-278US has a 15.6-inch widescreen with 1920-by-1080 resolution. The MSI has a plastic chassis with a metal-clad lid and palmrest sporting a hairline brushed finish. The full-size keyboard has traditional adjacent keys instead of the more popular chiclet design, and features a dedicated numeric pad.
The MSI GE620DX-278US is also equipped with several of the latest features, with USB 3.0 and USB 2.0 ports, a full-size HDMI-out port, and a dual layer DVD +- RW optical drive. Inside the MSI is a 640GB 7200rpm hard drive, offering more storage space than the Dell XPS 15z (Microsoft) ($999 direct, 4 stars) but not quite matching the 750GB of the Editors' Choice Samsung Series 7 (NP700Z5A-S03).
Equipped with a quad-core Intel Core i7-2630QM processor, the GE620DX-278US offers plenty of horsepower for all of your serious productivity tasks, from crunching numbers to graphic design. The 2.0GHz processor is paired with 8GB of RAM, so the MSI should be light on it's feet, even under a heavy processing load.
The GE620DX-278US is also equipped with a discrete Nvidia GeForce GT 555M graphics processor, the same GPU seen in the Asus N55SF-A1 ($1,249.99 list, 4 stars), and which garnered top scores in our graphics and gaming tests. The laptop also benefits from Nvidia's Optimus automatic switching technology, which helps conserve power by switching from discrete to integrated graphics when power is limited or when intense graphics processing isn't needed.
We haven't had a chance yet to test and review the MSI GE620DX-278US, but it looks to be a well equipped desktop replacement, with enough power for both work and play. For a full review of a similarly equipped desktop replacement, check out our current Editors' Choice, the Samsung Series 7 (NP700Z5A-S03).
More laptop reviews:
Dell XPS 13 (7390)
HP Omen X 2S
Apple MacBook Pro 16-Inch
Origin EVO16-S
onn. I3


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Bynes speaks out, Amanda Bynes is speaking out after her May 23 arrest.
The troubled 27-year-old took to Twitter after being released from custody on Friday, saying she doesn't "drink or do drugs." Bynes was arrested and taken to Roosevelt Hospital to undergo a psychiatric evaluation before heading to a Midtown precinct to be processed after allegedly throwing a bong out of the window of her West 47th Street apartment.
The former Nickelodeon star showed off her chopped hair in her mugshot photo, which made the rounds yesterday. In the picture, Bynes can be seen wearing a black sweatshirt and a scowl as she poses for police.
She took to Twitter last night to share her thoughts on her arrest and startling mug, tweeting:
Bynes faces charges of reckless endangerment, criminal possession of marijuana and tampering with evidence. According to Celebuzz, although the judge waived bail yesterday, he warned her that he would impose a steep bail if Bynes gets arrested again or fails to show up for her next court appearance on July 9.
UPDATE: Amanda Bynes took to Twitter again this afternoon (May 25) to expand on the details of her arrest. She claims an NYPD officer sexual harassed her and that she did nothing wrong.
"Don't believe the reports about me being arrested. It's all lies," she writes. "I was sexually harassed by one of the cops the night before last which is who then arrested me. He lied and said I threw a bong out the window when I opened the window for fresh air. Hilarious. He slapped my vagina. Sexual harassment. Big deal. I then called the cops on him. He handcuffed me, which I resisted, quite unlike any of the reports stated. Then I was sent to a mental hospital. Offensive. I kept asking for my lawyer but they wouldn't let me. The cops were creepy. The cop sexually harassed me, they found no pot on me or bong outside my window. That's why the judge let me go. Don't believe any reports."
Bynes speaks out news via huffingtonpost Tolong Share ya ^^


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The olive is the fruit of the olive tree that grows abundantly in the Mediterranean. It is from the olive that the olive oil, arguably today's most important health food, is extracted. If you've been watching My Greek Kitchen, you might have seen the episode where host Tonia Buxton and her family harvested olives the traditional way — by shaking the trees.
But the fruit has other culinary uses other than as a source of oil. You find them on pizza, pasta, canapes and even in cocktail drinks. They are sour and salty and slightly bitter. What most people do not know is that the sourness and saltiness are the result of fermentation and curing. In its raw state, the olive is not edible. It has to be soaked in brine or undergo some other form of curing in order to make it palatable.
In the market, you'll find green and black olives. They are often packed in jars and soaked in brine. What is the difference between green and black olives?
Aside from taste and color, they are from the same tree. The only difference is the ripeness — green are picked when they are immature, and black olives stay on longer. [Olives 101]
Some people balk at the taste of olives. My older daughter, Sam, says she hates it. But I had this theory that when served correctly, and in the right amounts, olives make a dish memorable. If olives enhance rather than overpower, even olive haters like Sam will appreciate them.


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How to get involved?
For a detailed description of the new model for Parent Carer Participation in Bristol, you can click on What is Parent Participation?
You can get involved by:
- being placed on Bristol Parent Carers' mailing list for updates on the parent carer participation process.
- attending the next Bristol Parent Carers event.
- being a member of the Steering Group.
- being a member of any of our 4 current focus groups working on:-
- transition from child services to adult services
- specialist education provision
- effective information
- access to social care services
- helping to develop the website.
- signing up for training opportunities to develop skills in:-
- public speaking
- parent participation
- developing and running a website
- helping in any other way that you can tell us about.
Reasons for getting involved
People get involved with Bristol Parent Carers for a whole range of different reasons. Perhaps you want:
- to know what's going on.
- to have your say.
- to improve things.
- to learn something new.
- to share your skills.
- to join with others in a similar situation.
This is your organisation, so the aim is for as many parent carers to get involved as possible.In this way we can share the load, and the time required from any one parent is reduced.
So join together, stay in touch, and get your voice heard!


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- BEARD & LOATHING Nick Offerman is fed up with the American political scene.
Actor-humorist Nick Offerman rattles off a list of North Bay spots he and his wife, actor Megan Mullally, like to visit when they're in the area: Canoe trips in the Russian River, dinner at Peter Lowell's in Sebastopol, a drive along the coast. "My wife and I are very big fans of the area," he says. "We are crazy about the whole coastline."
A North Bay visit for the couple always involves "some sort of intoxicant" says the co-star of NBC's hit sitcom Parks and Recreation. "We like to renew our vows whenever we get the chance."
And those North Bay adventures are all undertaken in the nude, correct?
"Absolutely," Offerman says. "Full nudity" is one of the many entendres on display in Full Bush, his one-man show coming to the Wells Fargo Center for the Arts in Santa Rosa on Oct. 3.
"If we can learn to cast off the oppressive social norms we've been brought up with, it leads to a happy and successful life," Offerman says. "Don't be embarrassed, go into things full bush. Sure, you're going to be in a compromising position at times, but you'll get a whole lot more done."
A follow-up to his American Ham show, Full Bush, says Offerman, will offer audiences songs of ribaldry, "rife with chuckles and chortles."
Offerman, a skilled woodworker, will be playing those songs on a ukulele he made himself.
"I am taking the opportunity to talk to the American audience about the things we can all be doing a better job of to try and keep ourselves ahead of those rascally Chinese," he says.
This involves "promoting good manners, and a rather natural lifestyle."
Offerman's had a busy few years, starting with his 2009 breakout role on NBC's Parks and Recreation as Ron Swanson. He published a book earlier this year, Paddle Your Own Canoe: One Man's Fundamentals for Delicious Living, and is working on another one.
Parks and Recreaction placed Ron Swanson into the pantheon of super-memorable sitcom characters for the ages: the hilarious hyper-libertarian with the outsized moustache and wood-working obsession.
The 44-year-old, farm-raised humorist from the Midwest might be thought of as a grunge-generation Garrison Keillor.
"I'm not wild man," he says. "I grew up in the country, and we loved to spend time in the outdoors, and I love the woods, I love canoeing. But I live in Los Angeles and I get out into nature for my escape and to daydream about a place in the woods to retire. I found a lot of happiness in the urban centers that I dwell."
Offerman says he tries to maintain his survivalist edge by cooking "a lot of meat on the open fire, and I let the beard grow."
His schtick rides roughshod over down-home territory with a wisdom that can be as biting as it is wistful. Some of it's corny, but when he brings the dirty, that can be pretty corny too.
Offerman has, in previous shows, mined matrimonial turf for territory, a comedic tradition that runs from Henny Youngman to Howard Stern to Louis CK and beyond. Yet there's nothing degrading or weird about his wife-related material.
"I tried to mine some comedy from how much I enjoy my marriage and how much I worship my wife," says Offerman. "And that always goes over very well, because it's sincere, but I don't want to come across as saccharine."
Offerman's "Rainbow Song," for example, "is a pretty, lovely song, but there's a little bit of anal sex in it."
Mullally and Offerman have on-again, off-again plans to tour with their Summer of 69, No Apostrophe show. It got put off this year when Mullally joined Nathan Lane and Matthew Broderick in Terrence McNally's It's Only a Play, now on Broadway.
"I'm on my own for the fall," says Offerman.
In the meantime, there's his tour and his next book, where Offerman says he plans to address the "consumerist polarization of political practices."
"The channels are steering us to purchase their products and consume everything from morning to night," he says. The list extends from food, clothes and cars "to the president we choose."
"I'm really fed up with the rut our nation has found itself in," he says. Everyone's comfortable, soft and tuned in to their affinity channel.
"I'm as guilty as anybody," he says. "I tune in to Colbert or Jon Stewart to find out what I think, and I think the other side, such as they are, tune in to Limbaugh for what they think, who to vote for, who they think is an asshole."


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Today I want to share with you some old texts that are my main source of inspiration in healthy bread baking. They were written in the second half of the 19th century by Ellen G. White: a prominent Christian writer, lecturer and an active and influential health reformer. The following is a collection of excerpts from her book "Counsels on Diet and Food" chapter 18:
The Staff of Life
"Religion will lead mothers to make bread of the very best quality…. Bread should be thoroughly baked, inside and out. The health of the stomach demands that it be light and dry. Bread is the real staff of life, and therefore every cook should excel in making it".
Religion in a Good Loaf. Sourness in bread is totally unfit for the human stomach.
"Some do not feel it is a religious duty to prepare food properly; hence they do not try to learn how. They let the bread sour before baking, and the saleratus (baking soda) added to remedy the cook's carelessness makes it totally unfit for the human stomach. It requires thought and care to make good bread. But there is more religion in a good loaf of bread than many think".
No soda or baking powder
"The use of soda or baking powder in breadmaking is harmful and unnecessary. Soda causes inflammation of the stomach and often poisons the entire system. Many housewives think that they cannot make good bread without soda, but this is an error. If they would take the trouble to learn better methods, their bread would be more wholesome, and, to a natural taste, it would be more palatable".
No Milk in Yeast Bread
"In the making of raised or yeast bread, milk should not be used in the place of water. The use of milk is an additional expense, and it makes the bread much less wholesome. Milk bread does not keep sweet so long after baking as does that made with water, and it ferments more readily in the stomach".
Light and sweet (not sour), small loaves thoroughly baked
"Bread should be light and sweet. Not the least taint of sourness should be tolerated. The loaves should be small, and so thoroughly baked that, as far as possible, the yeast germs shall be destroyed".
Hot from the oven: no good to eat
"When hot, or new, raised bread of any kind is difficult of digestion. It should never appear on the table. This rule does not, however, apply to unleavened bread. Fresh rolls made of wheaten meal, without yeast or leaven, and baked in a well-heated oven, are both wholesome and palatable".
"Zwieback, or twice-baked bread, is one of the most easily digested and most palatable of foods. Let ordinary raised bread be cut in slices and dried in a warm oven till the last trace of moisture disappears. Then let it be browned slightly all the way through. In a dry place this bread can be kept much longer than ordinary bread, and if reheated before using, it will be as fresh as when new".
Old is better
"Bread which is two or three days old is more healthful than new bread. Bread dried in the oven is one of the most wholesome articles of diet".
The Evils of Sour Bread
"The stomach has not power to convert poor, heavy, sour bread into good food; but this poor bread will convert a healthy stomach into a diseased one".
"In many families we find dyspeptics, and frequently the reason of this is the poor bread. The mistress of the house decides that it must not be thrown away, and they eat it. Is this the way to dispose of poor bread? Will you put it into the stomach to be converted into blood? Has the stomach power to make sour bread sweet? heavy bread light? mouldy bread fresh?"
(It seems that EGW didn't know rye sourdough in her times in The States. The sour bread she talks about is certainly wheat sourdough bread, which is very sour. I do not like it and, of course, I don't bake it by principle.- Carlos Perrone).
Hot Biscuits
"Hot soda biscuits are often spread with butter, and eaten as a choice diet; but the enfeebled digestive organs cannot but feel the abuse placed upon them".
No hot biscuits
"Hot biscuit raised with soda or baking powder should never appear upon our tables. Such compounds are unfit to enter the stomach. Hot raised bread of any kind is difficult of digestion".
Whole-Wheat Bread Better Than White
"Fine-flour bread cannot impart to the system the nourishment that you will find in the unbolted-wheat bread. The common use of bolted-wheat bread cannot keep the system in a healthy condition".
"For use in breadmaking, the superfine white flour is not the best. Its use is neither healthful nor economical. Fine-flour bread is lacking in nutritive elements to be found in bread made from the whole wheat. It is a frequent cause of constipation and other unhealthful conditions".
Grains in Bread May Be Varied
"All wheat flour is not best for a continuous diet. A mixture of wheat, oatmeal, and rye would be more nutritious than the wheat with the nutrifying properties separated from it".
No Sweet Breads sweetened with sugar
"Sweet breads and cookies we seldom have on our table. The less of sweet foods that are eaten, the better; these cause disturbances in the stomach, and produce impatience and irritability in those who accustom themselves to their use".
"It is well to leave sugar out of the crackers that are made. Some enjoy best the sweetest crackers, but these are an injury to the digestive organs".
(To see the whole chapter visit: https://egwwritings.org/?ref=en_CD.305¶=384.2356 )


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Search Engine Optimization for Doulas
Don't miss out on clients simply because your website doesn't show up well in search. The SEO Birth Plan will take you step by step through everything you need to know to get your birth or holistic practice found online. You'll find a perfect blend of self-paced video lessons and handouts with a private facebook group for extra support.
What's Included:
Ten self-paced lessons to rock the SEO on your doula website, including video tutorials, handouts & homework assignments.
- Understand how search engines work, and what Google is looking for.
- Develop a strong SEO strategy for your website.
- Learn creative ways to identify keywords using Google
- Transform your website content to boost your SEO
- Improve your website structure to increase your search rankings.
- Extra tips to help give your website an extra boost in search rankings.
- Simple steps to help Google recognize you as a local expert.
- Use SEO as an ongoing tool to grow your online presence.
The SEO Birth Plan was designed especially for those serving families in birth and postpartum, but will work well for any local holistic practitioner. Participants have included doulas, childbirth educators, midwives, yoga teachers, lactation consultants, photographers, holistic nutritionists, massage therapists, and counselors.
Learn SEO techniques for your website in 10 simple lessons!
I've worked really hard to make sure the content in this course is accessible, easy to implement, and extremely useful every step of the way. If you don't feel it has helped you learn the SEO skills you need to improve your website's search rankings just let me know within 15 days of purchase and I will refund every penny.
"A great resource for doulas with concrete, easy to follow steps to increase your website traffic and, ultimately, clients purchasing your services. I loved that the videos were so brief but still contained large amounts of helpful information. I was never overwhelmed. She will guide you from ignorant to confident in 10 short lessons."
Birth Doula
"It really helped demystify SEO for me! She did a beautiful job taking a subject that seemed so overwhelming and making it something that I understand and even feel excited about using! The easy to understand language, fantastic pace, and clear and beautiful PDF handouts made the whole process very straightforward."
Childbirth Educator, Doula, Lactation Support, & Photography
"Sarah is incredibly clear when describing what has been an overwhelming topic for me. I LOVE how she breaks down SEO into easily digestible pieces, sharing one simple and specific technique after another. Now I know what to do to reach my target market online. I feel confident in managing my own SEO strategy plan after taking this course."
Birth + postpartum doula agency, placenta encapsulation
Postpartum Doula
Frequently asked questions
If you can devote one hour of your time per lesson to both watch the video(s) and plan your website changes, you will have plenty of time for the ideas and information to take root. You could complete the course in a week, or spread it out over a few months. Good news - there is no such thing as falling behind. You will have full access to the course materials and facebook group for the lifetime of this course.
While this is an online course, it is important to me to be an active part of your learning process. I visit the facebook group twice a week to answer questions and contribute to the discussion. For extra support, you can choose an hourly website doula care package at a 10% client discount.
It's totally fine if you would rather not participate in the facebook group support. Seeing the questions and answers from other group members, however, is a great part of the learning process and will definitely add to your experience.
This course is designed for all of you, from the tech gurus, to the tech phobic. Setting up your website with good SEO is far simpler than you might imagine - all you really need is curiosity and a willingness to get creative with your website. I will guide you through every step of the way and answer your questions on the private facebook group! I promise.
I wish there were a 100% secure way to ensure that your website will be able to achieve top search results right away. Unfortunately, there is no way to accomplish this result for every website, even if you use every single tip I share. Your results will depend on a multitude of factors, many of which are in your control, such as good SEO practices on the important pages of your site, your creativity in choosing search terms and writing good content, and how inter-linked your website is with other sites on the web.
Ultimately, good SEO results take time. The changes you make will definitely have a great impact on your rankings within a few weeks, and then you should see a gradual improvement from there as you site gains in domain authority and you continue to build your online presence through tactics such as guest blog posts and link building. The more closely you follow the tips shared in this course, the better results you will see.
Taught by Sarah Juliusson, the Website Doula
I have supported birth and holistic professionals around the world as a Business & Website Doula since 2011, plus another 20 years of supporting families as a doula and childbirth educator. I bring a unique perspective to SEO work, moving beyond the technical to include a holistic perspective on how you can use SEO to better connect with your ideal clients and extend your reach in your community. Curious to read more of my story? Here you go!
"When it comes to web design and SEO, there's no one better to learn from than Sarah. My coaching clients who have taken this course come out the other side feeling empowered and ready to build (or improve) sites that rank highly on search engines, wow potential clients and drive inquiries. Sarah has a unique gift for understanding both the birth world and the online realm. The SEO Birth Plan breaks down the sometimes complicated art of finding clients online and gives step by step direction in a way that makes sense to both new and seasoned birth business owners. It is worth the investment 100x over."
Jessica English
Owner and Business Coach, Heart + Soul + Birth Pros, Doula Agency Owner, Birth Kalamazoo
"If you've been wanting to understand SEO and how to take your website to the next level, this is the course for you! The SEO Birth Plan course offers great value for the beginner and experienced entrepreneur. I like the easy-to-follow videos that clearly explain the concepts of SEO, which, quite frankly, seemed mysterious to me before taking this course. And I love how you learn to organically incorporate these practices into your website to make your rankings more sustainable. It's all about providing great content to your potential clients AND getting it in front of them, and this course definitely shows you how to do this!"
Birth doula & childbirth educator
"I am not a tech savvy person. I was blown away by the knowledge that Sarah had to offer. I felt the information was easy to understand and implement into your business and website – it kept me engaged and eager to learn. I am so excited to see the results that come from all Sarah shared! I can't recommend this program enough, I feel like everyone looking to have a successful business & wants their website to work for them needs the SEO Birth Plan!"
Nutritionist, Chef, Life Coach, Yoga Teacher & Doula
"I have finally reached the first page of search results! After two years of being stuck on page two of search results I have finally reached the first page for local birth doulas, and already am seeing an increase in site traffic. I'm still towards the bottom (#8), but now I have confidence that it will rise even higher. Thank you!"


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I'm a freelance animation director, animator and motion designer. Everything you see here (unless it says otherwise) has been designed, illustrated, directed and animated by myself. I take pride in being able to take an idea from it's initial concept all the way through to production.
A quick animation of a logo design by Roham Bayat - I just made it move


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Since 2014 the British Council in Venezuela has been working closely with the Venezuelan Education Ministry to strengthen the teaching of English in state schools. With the support of the British Council, the Ministry has initiated innovative training programmes for both secondary and primary teachers, introduced a new high school textbook and increased the number of classroom hours dedicated to English. This book describes (in Spanish) these initiatives and evaluates their impact.
This publication is free to download in pdf format below.


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Did you know that you could shop on our www.chainreactioncycles.com/us/en website?
Suggested in the name, the Urban 700, is the ultimate in urban commuter lights. With built in side visibility, day light technology, with a weatherproof design, and fully micro-USB rechargeable. The light is the perfect, ultra-bright front headlamp with integrated universal mounting system and a output of up to 700 lumens.
The save you the hassle of having to find and replace your bike lights battery every couple of days the Urban 700 is fully micro-USB rechargeable. This means that you can plug the light straight in to any standard USB port which can easily be found in your laptop, computer desktop, or as part of your smartphone charger. This makes charging on the go and universally easier than ever.
The light meets the FL-1 standard of water resistance which means that the Urban 700 is fully waterproof up until 5 metres of submersion. The body of the light has been specially cased to therefore protect the light from rain, snow, sleet, mud, grit and dirt. This means you don't have to worry about losing light no matter what the weather conditions are like. The light has also been developed to protect against high impact for when taking on potentially harder bits of road debris or accidental knocks and scrapes along the way.
When commuting in built up urban areas and dealing with a combination of other types of road users it's sometimes just as important to stay visible from the side as it is from the front. The Urban 700 comes with a special safety feature built into the channelling of the lights beam to provide a greater level of side visibility than with regular bike lights. This makes it perfect for cruising down multiple-lane roads, dealing with passing junctions, or when cycling pass potential reversing cars coming out of driveways.
The Motion Urban comes with 4 different light modes which you can change between dependent on your current cycling environment or on your depleting battery life. The light modes are also capable of working during daylight when dealing with the lights of other road users:
Buy Light and Motion Lights from Chain Reaction Cycles, the World's Largest Online Bike Store.
Order in the next
and choose Next Day Delivery at the checkout
Need help? Have a question?Get in contact with us
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Welcome to ChemDelta Bavaria!
ChemDelta Bavaria – the Bavarian chemical triangle: 18 companies, around 20,000 employees, over €10 billion in annual sales and around €3 billion in planned investments in the last years.
ChemDelta Bavaria is a joint initiative by the companies in the Bavarian chemical triangle. Its aim is to secure and improve the economic region's competitiveness – in harmony with the people and environment of South-East Bavaria.
ChemDelta Bavaria is the global chemical industry's key region at the heart of Europe.
++++++++++++ news ++++++++++++
Informationen über Sicherheitsmaßnahmen


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You watch your once mentally sharp parent decline before your eyes. Their uncontrollable anger and outbursts, the devastation of memory loss, and the worry that your parent will wander away from home and never come back are all overwhelming. When you are taking care of a parent with Alzheimer's disease (AD), you are trying to cope with your own grief over their illness, help them with their feelings of loss, keep them safe, make your immediate family reasonably content and work at your job. You may be wearing out, but caregiver guilt just will not let you say, "enough!"
Listen to Your Own Needs
Most of us, when we have a vulnerable loved one, want to take care of them. We aren't excited about having strangers take over the care of our loved ones, and our loved ones normally aren't excited about that idea, either.
However, outside care eventually becomes a necessity for many. When we are talking about elder care, often people jump immediately to the "nursing home" solution, since in days past, that was pretty much the only choice people had once someone couldn't stay at home, or with family. Things have changed now. We have more options, but that does not mean it is easy to accept them.
With more options for care comes more confusion. When is in-home help enough? Is assisted living the best option? What about nursing homes? Have they shed their bad reputations? Have new and increasing needs made them better or worse?
That Promise You Made
Hindsight can make us pretty smart. Sometimes, when our parents are younger and healthier, we make promises: "I'll never put you in a nursing home." We should not tell our parents this, since we have no idea what the future will bring. Also, that promise just underscores their view of the old style nursing homes, which were truly depressing places. So much has changes in long-term care facilities in recent decades.
Unfortunately, there are still areas of the country where nursing homes are far from excellent, and our whole nation has a long way to go before most homes are what they should be. However, we are talking about your reality here. We are talking about what is happening right now.
You may have made a promise that you might need to break. If that's so, remember that by caring for your parent for as long as you have has honored the spirit of your original promise. The idea is that you have done all you can to keep your elders safe and to help them through some tough times. However, times have gotten tougher than you expected, and you must look for other options. This is okay.
Do Not Make the Promise if You Haven't Already Done So
If you have not made this fateful promise, but your parents want you to do so, simply say, "I love you very much and will do everything I can to take care of you. We don't know what the future holds, but I'll do my best, always, to care for you in the best way I can." They may continue to pester you, but repeat this as needed.
Browse Our Free Senior Care Guides
Back to Options
The first place I recommend people check for help is their state website. Since each state is different, it's hard to give one answer as to what help is available in your community. By going to your state Web site (just type in the state name and scroll down until you find the official site), you should find some help. If you type "aging" into the search box of your state site, you'll find your state's version of the National Family Caregiver Support Program (NFCSP). Click that link and check in with these people. They will know what your state and community have available. They will also offer emotional support.
Many states have some federally funded hours of in-home care that go to waste because people don't know about them. The NFCSP folks should be able to point you to the organization in your area that would administer this help.
Click on any site that looks useful under this state aging help category. You may find quite a lot of help – or not much. Some states and communities offer an abundance of resources and information, while others have not been updated regularly in years.
In-home care can be expensive, but it is flexible. You may find an agency that can help your loved one, at least for awhile so you have a break from constant care, and then you can look for more permanent help. The main idea is that you need to get some relief.
Assisted living centers often have memory units, which generally offer good care to folks with dementia who are not having a lot of other physical problems. Assisted living is expensive. Expect that most of your elder's money will go for their care, if they need outside help. Unless people are wealthy, long-term diseases can eat up most of your parents' assets. You will have to accept that reality and so will they.
Your own health is expensive, too. If you get physically or mentally sick, you are not going to be able to care for your loved ones well, if at all. You may have to explain this to your elders (and to yourself) repeatedly. But believe me, it's true. If you are coming to the end of your rope with caregiving, you need to get help. Guilt is not an option. Your sense of guilt will only contribute to your parents' feeling of insecurity. So, please work on your own feelings about outside help. Think of this as giving more care, not about you caring less.
Assume as upbeat an attitude as you can, and start looking at assisted living facilities. Treat it as an adventure, even if your elders are complaining. Do your best to detach from their complaining and look anyway. Try to be cheerful but firm about any help you seek.
Nursing homes are for the sickest people. They, too, are expensive. Most people who spend a long time in a home end up spending all of their money and most of their other assets. At that time, they usually go on Medicaid, which is the government's program for helping the poor. A good nursing home should not give lesser care to someone on lower paying Medicaid than to someone who is on what they call "private pay."
When my loved ones moved to a local nursing home, I watched the staff closely. This was an exceptionally good home, to be sure, but I will say that I never, ever saw any difference in care based on how the home got paid. Nursing homes are all supposed to be this way. If you see a home that discriminates, report this home to your state ombudsman.
Back to Your Own Needs
When you have had enough, you have had enough. No one who is burned out is able to do his or her best to care for another person. Do not let this happen to you. Get help before you are at the stage where your loved one needs more attention and help than you can give.
When caring for a parent with Alzheimer's becomes too much for you, you are at risk for depression and other health problems. You may even put your loved one at risk because you cannot watch after him or her safely. Do it now before you completely break down. Do it for your family and yourself.
There is no shame in seeking help, nor should there be guilt. Seeking and providing the best care for your aging parents takes a team. You do not have to be the sole person responsible for meeting for every need.


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2 Bears release new remixes EP
Last year the 2 Bears were responsible for one of my biggest tracks of the year, the unforgettable 4×4 work out 'Be Strong'. Now they have announced they will be releasing a remix EP with the likes of Dj Sneak and Totally Enormous Extinct Dinosaurs reworking tracks from the forest dwelling duo's second E.P
Southern Fried Records released the Curious Nature EP, the second from the 2 Bears aka Raf Daddy and Joe Hot Chip in 2010. The label is now releasing a 5-track remix EP, with reworks from Dj Sneak, Totally Enormous Extinct Dinosaurs, rising house talent Midland as well as Supabeatz and Gingy.
Highlights come courtesy of the Sneak and TEED, with both tracks destined to spend the next 6 months destroying dance-floors across the globe.
Curious Nature EP Remixes is available on Southern Fried on 14th February.


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Hi Jeanne! Welcome to The Fox's Hideaway! I'm so glad you could stop by.
Me too! Thanks for having me.
Describe Charisma in a single tweet.
Super shy girl takes super shady DNA-altering drug to become super shiny. It works, but might also kill her.
Where did the idea for this story come from?
A multitude of sources, including a trip overseas that had me obsessing over viruses, all morphed into the final story line. But one peek at your TV or social media will show that charisma is a valuable commodity that I believe many would take huge risks to acquire.
Okay, I HAVE to ask about the cover. What is with the rabbits (bunnies?), especially that lonely pink one in the middle?
I love the cover! Kudos go to Danielle Calotta, who designed it. Although there are no bunnies mentioned in the story, other less-fluffy lab animals are. In fact, the main character is a lab animal of sorts. But bunnies are the cutest, and the pink one is about standing out from the crowd.
Describe your main character, Aislyn, in six words or less.
Brainy introvert unaware of her potential.
What is her main mission in the book?
At first, it's to break free from her inhibitions so that she can lead a full life and advocate for her seriously ill brother. However, once she realizes how dangerous Charisma is, her goal is to survive and find a cure.
I am a very shy person in real life, so I'm really intrigued by this drug that is supposed to change that. So if you were trying to sell this drug to me (hypothetically speaking, of course), what would your hook or tagline be?
Hey, Holly, what's your dearest dream, and what's stopping you? Nothing a rockstar personality couldn't help with, I'll bet. Now, imagine the trajectory your life could take if you approached everything with boldness and had the power to influence whomever you wanted. That dream sounds a whole lot closer, doesn't it? Just one teensy dose, as quick as a flu shot, and your future expands—pow!
(Wow, I might just have to try it now). And lastly, what do you hope people take away from your book?
Mostly that they have a fun time reading it. But if got them talking about the ethics of genetic enhancement, which will be a real thing one day, so much the better.
Thank you so much for stopping by the blog and answering my questions, Jeanne!☺
My pleasure! (BTW, have you decided to try a dose of Charisma yet?)


text: DO YOU NEED A TRUST? There are many different reasons to establish a trust. Do you have a family member who is unable to manage their affairs due to intellectual impairment or addiction? Do you have family members who are under the age of 18? Do you have a family member who is at risk of divorce, bankruptcy or litigation? Are you part of a blended family? Are you interested in tax savings for your beneficiaries? Would you like to support charitable causes now or as part of your estate?


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Francis Carr Begbie — Occidental Observer Nov 11, 2015
Sunday, November 8th, was Remembrance Day, and members of the National Front made their traditional march to the Cenotaph in London as a tribute to Britain's war dead. As part of the NF's Forgotten British Heroes Campaign, a special mention was made of a young Sheffield gunner called Harold Yates who was killed in Palestine in 1945, six months after the end of the war in Europe when Jewish terrorists in British uniform attacked a railway junction.
At first glance it seems as if the story of 25-year-old Gunner Yates would scarce merit a footnote. After all, he was only one among hundreds of thousands of others being remembered in similar ceremonies across Britain. But there is an appalling story behind the death of Gunner Yates. For two senior politicians were complicit in the attack that killed him. Tipped-off about the impending assault, they gave it their tacit approval, agreed to turn a blind eye, said nothing and warned no-one.
This is a story of treachery, squalid political expediency and a despicable indifference to the lives of British servicemen. It has not been told in full until now. In 1945 the Palestine Mandate was in the grip of a Jewish insurgency aimed at forcing the British to allow a flood of Jewish immigrants from Europe into the territory. The British Foreign Secretary Ernest Bevin was determined to resist, as it not only would have been in breach of the undertakings given to the Palestinians by the Balfour Declaration but it would have also meant losing the support of all other Arab countries in the region. To allow this to take place would have meant a war in the Mandate, so Bevin had no option but to maintain a desperate policing action to keep the two sides apart.
But the problem did not end there. The 1945 general election had not only swept Churchill out of office and the Labour Party into power, but among the Labour's landslide were no less than 46 Jewish MPs. The overwhelming majority of these were not only fanatical Zionists, but they were supported by a loyal auxiliary of non-Jewish MPs at the highest levels of the party, including two men, John Strachey and Richard Crossman, both to become prominent names in post-war Britain. The collusion of these two in an attack that killed a British serviceman is a paradigmatic example of the abasement of non-Jewish politicians who prostitute themselves to Jewish interests.
Both were typical of high-flying Labour ministers at the time and far removed from the English working class they claimed to represent. They both came from well-to-do backgrounds. Strachey was a product of Eton and Oxford. Sophisticated and urbane, he moved in the most politically fashionable circles. In the thirties, this one-time Communist had moved into the Labour Party and had worked hard to ingratiate himself closely with Jewish wealth and political power. When the White working class of the East End of London rose up against Jewish predation under the banner of the British Union of Fascists, Strachey had organised counter-demonstrations with Communist and Jewish street agitators. Working with wealthy Jewish publisher Victor Gollanz and academic Harold Laski, Strachey helped launch the Left Book Club which became an energetic source of anti-German propaganda. He was elected a Labour MP in 1945 and became Under Secretary for Air.
Richard Crossman attended the highly prestigious and exclusive Winchester College before obtaining a double-first in Classics at Oxford. He later worked for the television magnate Sidney Bernstein, but it was Zionist leader Chaim Weizmann who most impressed him. Weizmann was a roving emissary promoting the Jewish cause who was buoyed up by Lord Rothschild's generous financial contributions. With Rothschild's patronage, Weizmann was able to buy influence across the globe. Crossman described him as the greatest man he had ever met.
Richard Crossman's political career was to rise sharply with his support of Zionism. Crossman said that Jewish state should have been forced on the Arabs by the British at the earliest possible time and that Jewish immigration should have been built up as fast as possible. It was a view he repeated through the pages of the New Statesman which was published by the Jewish founder of the Fabian Society, Sidney Webb. (Crossman was later appointed editor). Crossman became an MP in the 1945 government at the height of the Palestine emergency.
The Jews in Palestine were represented by the Jewish Agency for which the British Board of Jewish Deputies acted as representative in Britain. The Jewish Agency maintained that it had no power over the terrorist gangs operating in Palestine, but this was a deception. In fact, the Haganah was its military wing.
In late 1945 the Jewish Agency decided it had to carry out a terrorist spectacular against British forces in Palestine as a show of strength to its American backers. But worried that this would trigger a brutal clampdown and reprisal from the British, the action had to be carefully measured. The Agency therefore planned one further large-scale operation to paralyse Palestine's railways.
There the matter might have rested until a remarkable passage was published in Professor Hugh Thomas's 1973 biography of John Strachey which gave the game away:
Only on Palestine did Strachey have any serious dispute with the government. One day, Crossman, now in the House of Commons, came to see Strachey. The former was devoting his efforts to the Zionist cause. He had heard from his friends in the Jewish Agency that they were contemplating an act of sabotage, not only for its own purpose but to demonstrate to the world their capacities. Should this be done, or should it not? Few would be killed. But would it help the Jews. Crossman asked Strachey for his advice and Strachey, a member of the Defence Committee of the Cabinet, undertook to find out. The next day in the smoking room in the House of Commons Strachey gave his approval to Crossman. The Haganah went ahead and blew up all the bridges over the Jordan. No-one was killed but the British Army in Palestine were cut off from their lines of supply with Jordan.
Incredibly, at a time when the British Army was taking casualties from Jewish terrorist attacks in Palestine, here were two senior Labour members — one a Minister — conspiring to agree to an attack on British soldiers.
But Prof. Thomas was wrong to state that no-one was killed in the attack. The huge Haganah attack is known in Israel as "The Night of the Trains" and took place on the night of October 31, 1945. The railway network was severed in 153 places. Three police launches were sunk and many railway yards and the Haifa oil refinery attacked by Jewish gangs. At one railway junction, 25-year-old Gunner Yates from Sheffield was shot to death. Perhaps he let his guard down by the approaching figures in British officers' uniforms.
A few days later, the British finally broke the Jewish Agency code, and Crossman and Strachey spent an agitated next few days fearing their role might be discovered. Certainly in the war that had ended just six months earlier, traitors had ended up on the end of a rope for far less.
But in the end it was pressure from the US that forced Britain to allow the Jews into Palestine. In the mid-forties, a bankrupt Britain was dependant on American goodwill for her economic survival through an aid program known as the Marshall Plan. President Truman, as he later explained frankly in his memoirs, was equally dependant on Jewish goodwill for his presidential campaign funds.
This story might never have come to the light but for the authors of a remarkable book published in 2006 which exposed how Britain's Labour Party had been captured and exploited by Jewish interests from the earliest days of the 20th century. As noted in Publish It Not — The Story of the Middle East Cover-Up by Michael Adams and Christopher Mayhew (a principal in the affair), "the British government was subjected to ruthless pressure from Washington to get the Arabs to accept the Zionist demands. It was a disgraceful abuse of power." On one occasion the US Ambassador insisted that the British government comply with the President's request that Britain admit a hundred thousand Jewish refugees to Palestine "immediately." Bevin and Christopher Mayhew, his Under-Secretary, objected to what was an obvious recipe for war with the Arabs.
The (US) Ambassador then replied carefully and deliberately that the President wished it to be known that if we could help him over this, it would enable our friends in Washington to get our Marshall Aid appropriation through Congress. In other words we must do as the Zionists wish — or starve. Bevin surrendered — he had to — but he was understandably bitter and angry. He felt it outrageous that the United States, which had no responsibility for law and order in Palestine (and no intention of permitting massive Jewish immigration into the United States), should, from very questionable motives, impose an impossibly burdensome and dangerous task on Britain. (pp. 17–18)
Publish It Not is a remarkable publication not least because both of the authors were men with impeccable socialist and anti-racialist credentials. Mayhew was a Labour minister while Adams was a Middle East correspondent for the Guardian.
They were outraged at the way in which the Arabs were treated and that Britain's assurances to them counted for nothing. But equally they were appalled at how Labour, Britain's main progressive party, seemed to have been, to a large extent, taken over by Jewish influence and money.
Despite their naiveté over the ethnic nature of the conflict, their book has penetrating insights and fascinating information about the perversion of the Labour Party in the twentieth century. Throughout the text they insist on the prophylactic word 'Zionist', but it avails them of nothing. In a memorable phrase Mayhew writes:
But a striking feature … has been the relentless way in which those of us who chose to speak up for the Arabs have been harassed by our opponents. They seem not to be satisfied with trying to prove us wrong; they have to prove us wicked as well. Indeed they sometimes showed themselves much less concerned to answer our arguments than to damage our reputations — and they can be surprisingly unscrupulous in the way they go about it.
The capture of the Labour Party by Zionism had been a remarkable phenomenon, wrote Mayhew:
It is a remarkable fact that the Labour Party leaders, though representing a movement which has always vigorously opposed racialism, colonialism, militarism and the acquisition of territory through conquest, never appeared to have made any (recorded) public criticism of Israel at all.
All the more amazing when you compared it with South Africa which practised many of the same policies but which was treated as a pariah. Often it was the same Jewish Labour MPs who led the charge against South Africa who were most active in defence of Israel.
Mayhew was one of the huge Labour intake of MPs who entered parliament in 1945 and soon he was in government office dealing with the fraught question of Palestine. He freely admits that at the time he was new to the Palestine problem and did not understand all the ramifications. At the time it seemed a sideshow. The British Foreign Office was struggling with a number of issues. India and Pakistan had to be given their freedom. The Marshall Aid plan had to be pushed forward. Institutions had to be created for a divided Germany. NATO was about to be formed.
Soon, in addition to an intense whispering campaign, he was being subjected to verbal intimidation, mind games and harassment from increasingly shrill "Zionist" deputations who were demanding more Jewish immigration into Palestine from Europe.
These deputations were always well-informed, articulate, demanding, passionate and ruthless. The most formidable of their spokesman, unquestionably, was Mr Sidney Silverman; he would attack me personally in the most merciless fashion, placing on my shoulders the responsibility for the deaths and suicides of the immigrants whom we had turned back.
On 11 July 1948 a young MP called Christopher Mayhew rose in the House of Commons to speak in an Adjournment Debate about recognition of the state of Israel. The debate had been initiated by an ambitious and energetic backbencher called Harold Lever, and Mr Mayhew was to answer for the government as the Under Secretary at the Foreign Office.
"With an importunity typical of Zionists at that time Mr Lever had started the debate at eight o'clock in the morning after an all-night sitting, and my reply sounds appropriately tired and irritated." Mr Mayhew pleaded for balance and then said "Has my Honourable Friend ever heard that there is an Arab point of view?"
Thirty years later Mayhew still remembered the scene vividly. While he was accompanied by his sole supporter, his Private Secretary, he faced the massed ranks of the Zionist lobby in parliament on the other side. A group of twenty or thirty pro-Israeli Labour members, most of them Jewish. They included Sydney Silverman, Maurice Edelman and Ian Mikardo. Among them was Israel's most devoted non-Jewish supporter Richard Crossman.
Mayhew's boss, the Foreign Secretary Ernest Bevin, felt the pressure too as he was constantly being harried by groups of Jewish Labour MPs. At the end of one tense Question Time session he exploded. "We must also remember the Arab side of the case — there are, after all, no Arabs in the House." This remark provoked uproar and endless accusations of anti-Semitism. But of course there was no counter pressure from the Arabs whose homes, lands and property these Jewish immigrants were seizing. Bevin was passionately anti-Zionist and held that Zionism was basically racism.
Years later an attempt was made to place Mayhew on the pro-Israeli payroll. It happened in 1951 after he had lost his Parliamentary seat and was working as a freelance television journalist. The Director of the World Jewish Congress, Mr A I Easterman summoned him to his office in Cavendish Square, and proposed an informal arrangement. Whenever Mayhew was asked for advice by Mr Easterman, he would be paid "a substantial honorarium" — an obviously corrupt "consulting" arrangement. This was to be a personal arrangement between the two with nothing in writing. "In fairness to Mr Easterman, it should be said that he has denied my version of events." Easterman claimed he did not make the offer and in any case the World Jewish Congress was a far from wealthy organisation. "All I did say to him about finance was that, naturally, we would re-imburse him for any expenditure that he might incur on our behalf," Easterman said.
In 1953 Mayhew made his first visit to a Palestine refugee camp and learned first-hand what had been going on. For him, this visit destroyed the myth that in 1948 the refugees had fled voluntarily. This was underlined when the refugees from the 1967 war behaved in the same way and suffered the same fate. They left their homes in panic before the advancing Israeli armies and were then prevented by the Israelis from returning. The pattern was the same in both wars with the exception of the massacre of the village of Deir Yassin.
This was important. Before 1967 the myth that the 1948 refugees had fled voluntarily was almost universally believed in European countries and repeated across the media. During his visit, Mayhew began to feel actively committed to the Palestinian cause. He was shocked by the Israeli leaders' callous and self-righteous indifference to the suffering of the Palestinian refugees (which they stated to their faces) and he made his views public.
This had consequences for his political career. A senior colleague told Mayhew that frankly it had been his attitude to Israel that counted against him. This was confirmed in an article in Israeli newspaper Maa'riv in 1974.
He wasn't the only one. One charge that Jewish leadership in Britain has always been sensitive to is that of "dual loyalty" — disloyalty by any other name. Despite the passionate embrace of the cause of Israel by many Jewish Labour MPs, the charge of dual loyalty always left them spitting with indignation.
Andrew Faulds was one Labour MP who did question the matter of dual loyalties. He was not only taken to task by the Prime Minister but deprived of his post as a Front Bench spokesman. In letter to him PM Harold Wilson wrote: "It was because of 'uncomradely behaviour'… you caused great offence by impugning the patriotism of Jewish Members of Parliament by implying that they had dual loyalties."
Mayhew notes that while Zionist political contributions to politicians in the United States had always been discussed with admirable frankness (an exaggeration at best), the discretion surrounding such arrangements in Britain meant they were kept confidential.
But one hint as to how things really worked in Britain came in a letter published in a Tel Aviv newspaper in which an Israeli diplomat in the UK defended his embassy against charges that they were not doing enough to sway political opinion. Mr Benad Avital said that he and the Ambassador met personally with 100 supportive British MPs before one debate. "Inevitably, we concentrate on target groups which we consider opinion-making, rather than on every man in the street. This policy has so far paid well" (italics added). As always, the default option for Jews is to pursue a top-down strategy.
Young Harold Yates was far from the last Briton to be killed by terrorists in Palestine in 1945. In the months immediately following VE day, the casualty list included the following colonial police officers: George Wilde, Bertie Sharpley, James Barry, Gordon Hill, Denis Flanagan and Richard Symons.
On December 27, 1945 in an attack on the CID HQ the following officers were killed : Edward Hyde (28), Noel Nicholson (20), George Smith (44) and Privates Likoebe Kurata, Vincent Nthinya, Tapotsa Ntisa all in African Pioneer Corps.
The remains of Harold Yates are interred at Ramleh War Cemetery, Israel, Plot 7, Row C.


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The 1957 Topps baseball set offers several firsts, lots of rarities, and a large, evergrowing collector base. This popular set includes the rookie card of Brooks Robinson, the last regular issue card of Roy Campanella, and a card of Henry Aaron showing Hammerin' Hank batting lefthanded. From the #1 Ted Williams to the #407 Yankee Power Hitters, the '57 Topps Baseball set is a classic all the way.
For the first time, Topps issued the '57 set with actual color photographs, not just the handcolored black and white photos of earlier years. The crisp, clean card design is coupled with the gorgeous color photos to make one of the most attractive sets Topps has ever produced.
The '57 set was issued in five separate series: 188, 89176, 177264, 265352, and the final 353407. While it is typical for the final series to be the scarcest, it's the fourth series(265352) that's the most difficult to locate in the '57 set. In addition, the lifetime statistical information on each player's card was expanded for the first time.
Today's standard 2 1/2" by 3 1/2" card was introduced with the 1957 set. Although smaller than the previous years, the new format was immediately accepted by the collecting public as "just right." Another innovation in '57 was the combination star card. Card #400 featured Campanella, Furillo, Hodges, and Snider while #407 offered both Mantle and Berra. Combination cards had been issued before, but not star combinations. Collectors who are building their first highgrade '57 Topps Baseball set will find it challenging. The usual grading intricacies are there, of course, such as corner wear, focus, gloss, depth and brilliance of color, etc. But two other factors plague the set as well. One is centering; numerous cards from this set are found with below average centering. Two, quite a few cards have "print snow," an absence of color onthe surface due to a printing defect.
- The key cards in the set are as follows:
- #1 Ted Williams
An immensely popular card showing a full waist up portrait of Williams in his classic batting pose with the full color photo of his vintage uniform. The first card in the set; therefore, extremely difficult to find in Near Mint to Mint condition.
- #10 Willie Mays
Another classic looking card, highly popular, that features a great player. Many, many examples have print snow problems. Difficult to find well centered; equally elusive with deep, rich background color.
- #18 Don Drysdale
In great demand as it's Drysdale's rookie card. Not rare except in high grades. A "problem card," as 70% of the examples we encounter have back centering worse than 90/10.
- #20 Hank Aaron
This gorgeous, highly popular vintagelooking card tends to be difficult to locate without print snow or with deep, bold color. A real find in top grades.
- #35 Frank Robinson
Demand keeps this card elusive, as it's Robinson's rookie card and quite popular.
- #76 Roberto Clemente
There are no specific problems with this card, it's just so popular that locating a highgrade copy can be a real challenge. Some examples show extraordinary gloss for some unknown reason. When available, it's a gorgeous card and an immediate seller.
- #95 Mickey Mantle
"Super popular" is the only way to describe this issue. It's tough to find one wellcentered, or with vivid background color, or without printing flaws. A Near Mint to Mint copy with eye appeal is in heated demand.
- #302 Sandy Koufax
A condition rarity that has proved to be ultraelusive in high grades. Not rare in lower conditions, but very few top quality specimens surface.
- #328 Brooks Robinson
This immensely popular player's rookie card is in great demand. Robinson's "little kid" look seems to appeal to everyone.
- #400 Dodgers Sluggers
Of all the key cards mentioned, this is the toughest one in high grades. I'd estimate that nine out of ten copies show some degree of print snow, have centering problems, and exhibit substandard color and gloss. A real sleeper if you can locate a highend example.
- #407 Yankee Power Hitters
Not rare, but as the last card in the set it's highly popular and in great demand for its attractiveness. Most importantly, it has both Mantle and Berra on it.
- Checklists
The four checklists are not numbered, so some collectors include them in the set and others don't. All are rare in any condition; top quality examples are extremely rare. In fact, the third and fourth checklists deserve the accolade of ultrarare. As this small but significant segment of the '57 set becomes more appreciated, prices will increase dramatically.
- #10 Willie Mays
The 1957 Topps Baseball set has a phenomenal track record. Demand for this set has remained high regardless of the general state of the overall market. Today, it will take a collector two or three years to complete a Near Mint to Mint set at a cost of $12,000 or more. Even though the '57 set represents a challenging undertaking, the collector will know that he or she has completed the set that represents the pinnacle of baseball card design.


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Gaming PC
When 16-year-old William Schindler received an unexpected inheritance from a long-lost uncle, he knew exactly where the money was going. "I wanted the ultimate gaming computer, something so fast I wouldn't have to worry about speed for years," says the high-school student from Yorktown, Virginia. This February, he spent $8,700 on a Falcon Northwest gaming box, with a 3.2-GHz Pentium 4 processor, 1GB of memory, a 256MB ATI Radeon 9800 XT graphics card, and a pair of 250GB, 7,200-rpm hard drives.
Now, 500GB of hard drive space is a tad excessive; a 160GB hard drive is adequate. And the price raises eyebrows: You can get a killer gaming system for $2,400 to $5,000. Otherwise, serious gamers should follow William's lead. His mega-desktop also includes a Creative Labs Sound Blaster Audigy 2 ZS sound card, six-piece speaker set, and 21-inch monitor, providing room-rattling surround sound and jaw-dropping graphics. He even shelled out for an exotic case design. "Mine," he says, "has a picture of the grim reaper on it."
[A] Creative GigaWorks S750 7.1 speakers. The S750 speakers provide surround sound for gaming and DVDs. The set includes four speakers, one center channel, two additional rear channels, and one subwoofer. With 7.1 surround sound, gaming is truly immersive. And opponents will have a hard time sneaking up behind you with all those surround channels.
[B] The Creative Labs Sound Blaster Audigy 2 ZS sound card. You can take advantage of the Audigy 2's abundance of input/output ports by connecting external speakers, an MP3 player, microphones, a MiniDisc player, or other audio devices. It also supports up to 7.1 surround sound (seven channels plus a subwoofer).
[C] A wired keyboard. Make sure your keyboard has customizable keys for playing first-person shooters or real-time strategy games. And slight lag time occurs with a wireless keyboardwhich could mean the difference between life and death.
[D] For gaming fanatics, look to game pads, joysticks, and force-feedback wheels as alternative game tools.
[E] A 21-inch or larger CRT or a 19-inch or larger UXGA (1,600-by-1,200) fast LCD (less than 16-ms pixel response time). Although only CRTs will suffice for most gamers, today's fast LCDs are improving. And though CRTs are faster, LCDs are lighter. With a 15- or 17-inch LCD monitor, gamers can take both their tower and monitor to LAN parties.
[F] At least an ATI Radeon 9800XT or nVidia GeForce 5950 Ultra with 256MB or more of graphics memory. Gamers want the fastest 3-D gaming card, and these graphics cards fill the bill. But this may change before the ink is dry on these pages. Look for PCI Express graphics cards soon, which will supplant AGP 8X shortly. (By the time you read this, the GeForce 6800 Ultra series graphics cards will likely be available, as will the ATI Radeon X800 XT.)
[G] The Intel 875P chipset or the nVidia nForce3 250Gb platform (for AMD processors). The 875P has an 800-MHz FSB, dual-channel DDR400 RAM, integrated SATA RAID, and 8X AGP. Dual-channel DDR doubles the memory bandwidth, and SATA RAID doubles hard drive throughput. The nForce3 250Gb platform also features dual DDR400 memory, 8X AGP, and on-board 5.1-channel surround sound, as well as Gigabit Ethernet with security and integrated IDE/SATA RAID.
[H] An AMD Athlon 64 FX-53 or Intel Pentium 4 Extreme Edition. Gamers who overclock their chipsets to improve performance should choose the AMD chip. But for those who don't want to open their boxes, the 3.4-GHz P4 EE will work.
[I] A DVD±RW drive and a DVD/CD-RW combo drive (for copying from disc to disc). A DVD±RW drive lets you burn discs in both formats to play on your DVD player.
[J] At least six USB 2.0 ports and two FireWire ports, plus an NTSC output. An abundance of USB ports (and a couple of FireWire ports) are essential for hooking up game controllers, external hard drives, and the like. (Four USB ports and one FireWire port should be on the front.)
[K] 1GB of DDR400 SDRAM. The fastest memory available, DDR400 is ideal for current and future games.
[L] A wired or fast wireless optical mouse. An optical mouse has a faster response time and won't get slowed down by dirt and grit (as a mouse ball can).
[M] At least one 160GB, 7,200-rpm SATA hard drive. A SATA hard drive is slightly faster than standard IDE, and the thinner cabling increases airflow. If you have the budget, you should go with dual SATA hard drives in a RAID 0 array.
[N] A cool chassis. Nothing's stopping you from getting a customized paint job, if your wallet permits. But if money's tight, there's always basic black with a see-through panel and fluorescent tubing.
[O] An 802.11g PCI or USB wireless solution. Wireless connectivity is a plus for those who want to play online games throughout the house but don't want to string Category 5 cable.
[P] Integrated 10/100/1,000 Ethernet for wired connectivity.
Windows XP Pro. We recommend Win XP Pro over Win XP Home because of such features as password-protected local file-access control, Remote Desktop, Encrypting File System, Roaming Profiles, SNMP, and Network Monitor. XP Pro also has advanced network and network-sharing options, which are useful for LAN parties.
Real-World Systems
($2,400 to $5,000): ABS Ultimate M6, Alienware Aurora Extreme, Apple Power Mac G5, Compaq X09, Dell Dimension XPS, Gateway 710G, Polywell Poly 900NF3, Velocity Micro Vision 64, WinBook PowerSpec 9361
Online Extra
Click here to download features lists for the systems mentioned above.


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Advanced project to help model customer and broker behaviours, and help predict and improve policy persistency. We created a set of bespoke time-to-event models using traditional and Bayesian inferential methods to understand key drivers.
Exploratory project to find non-invasive insights into the communication patterns between the client, customers and brokers. We mined large textual datasets, using advanced natural language processing and lightweight interactive dashboarding.
We are a small team with expertise in machine learning, statistical modelling, actuarial science, software development, and financial systems. A network of strategic partnerships allows us to bring in specific capabilities for projects.
Our core team combine many years experience in financial and business services, with a focus on statistical modelling, software development and business change.
Jon founded Applied AI in 2013 to bring a bespoke data science consulting service to the financial sector. His twelve years technical and advisory experience are sought by senior audiences worldwide.
We are a regular sponsor of the R in Insurance Conferenceand our team also organise, speak at and volunteer within several technical groups and industry events.
Applied AI worked with us over the course of a year helping to setup our in-house data science function. Their approach sits at the sweetspot of data science theory and insurance practice, and they enabled us to establish the department from scratch at low risk to perform high quality data science. They worked with internal staff, external contractors and university researchers and we found their help extremely valuable.David Kavanagh - Head of Analytics, Ireland - Zurich Life Assurance
Applied AI helped us clearly demonstrate how we can make better use of our internal data. The team worked closely with our actuarial staff to merge their custom socioeconomic information with our internal data to find patterns in our customer base and identify significant cost savings. The project was very successful and results were communicated to the board with a demonstrable recommendation that we start down the path of using our data more effectively.David Roberts - Actuarial and Finance Director - New Ireland Assurance
Applied AI Ltd is a limited company registered in England and Wales #08609649 152 City Road, London, EC1V 2NX, UK Applied AI Ltd © 2013 - 2016


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Check out the live stream for Germany's Rock AM Ring festival which features live performances from KoRn, Coldplay, System of a Down and more. We have only listed the bands that we highly recommend you watch on the schedule below but if you are curious about the full livestream schedule, then head over to the Rock Am Ring website for the full list.
01.50pm PST - COLDPLAY
03.25pm PST - KORN
09.20am PST - ALTER BRIDGE
01.30pm PST - SYSTEM OF A DOWN


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Combustion and Pollution Control
The Research Centre for Combustion and Pollution Control (CPC) has been established since 2001. During the previous 10 years, the CPC Research Centre successfully develops a critical mass to deal with combustion-related air pollution problems. Because of our excellent effort in serving the industry, PolyU is recognized as a very good partner in dealing with the combustion-related air pollution problems in Hong Kong, or perhaps, the Pearl River Delta region.
During the previous 10 years, the CPC Research Centre makes the best effort to excel PolyU and the achievements can be recognized from the following indicators:
- There are many research projects conducted and more than half of them are supported by external funding.
- There are various activities performed with significant contribution to teaching and learning (including program development) with the aid of our research work.
- There are many research students graduated or working under our supervision.
- There are many prestigious international journal papers published and many conference proceedings presented.
- There are several conferences, seminars and workshops organized.
- The key members have obtained very good SCI citation counts.
- There are several consultancy projects conducted.
- There are several patents granted in burner design and development of air pollution control systems.
Membership of CPC
Name Institute Prof. CS Cheung (Centre Director) ME/PolyU Prof. TL Chan (Deputy Centre Director) ME/PolyU Prof. WWF Leung ME/PolyU Prof. CW Leung ME/PolyU Dr WT Hung CSE/PolyU Dr Z Ning SEE/CityU Dr LK Sze Exova Warringtonfire – Hong Kong Dr KK Tong Dah Chong Hong (Motor Service) Dr TT Wong ME/PolyU Dr P Zhang ME/PolyU Dr L An ME/PolyU
Affiliated members of CPC
Name Institute Dr YS Choy ME/PolyU Dr RCK Leung ME/PolyU Dr WO Wong ME/PolyU
The CPC Research Centre is established to create and develop a critical mass in the fundamental and applied studies of combustion-related air pollution problems and their control. The specific objectives are:
- To acquire funding to support research activities in dealing with energy utilization from combustion processes and control of the air pollution problems generated by the mobile and stationary sources. A major emphasis will be on the outputs and impacts of these activities including application of created knowledge to help the industry and community, publication of quality papers, and training of research students in the relevant areas.
- To provide professional services to the Government/industry/community in solving problems related to combustion-related air pollution, through carrying out consulting projects, arrangement of technical workshops and seminars, and development of engineering and scientific devices/systems/strategies.
- To underpin graduate/undergraduate teachings with knowledge created from research and development works. Efforts will be made to improve and develop the academic program curriculum in tackling the transportation-related air pollution control, and design of environmental-friendly combustion systems and products. Efforts will also be made to provide graduate/undergraduate final year projects in the relevant areas.
External Collaborations
Members of the CPC Research Centre maintain a very good collaboration in research and academic activities with other departments of PolyU, as well as other universities and institutions, both local and overseas. Through the implementation of these activities, excellent partnerships have been established in conducting research projects and developing program curriculum with the following universities/institutions:
- McGill University, Canada
- Chinese Academy of Sciences, China
- Nanjing University of Science and Technology, China
- Shanghai Jiaotong University, China
- Tsinghua University, China
- University of Science and Technology of China, China
- Xi'an Jiaotong University, China
- Zhejiang University, China
- The Environmental Protection Department, HKSAR, China
- The Hong Kong Institution of Engineers, HKSAR, China
- The Hong Kong University of Science and Technology, HKSAR, China
- The University of Hong Kong, HKSAR, China
- Institution of Engineering Designers, UK
- Purdue University, USA
Representative Research Projects
- Emission and thermal characteristics of gas-fired premixed or diffusion flame burning gaseous hydrocarbon fuel enriched with hydrogen fuel
- Highly efficient and permeable polymer based nano-fiber filter media for removal of sub-micron aerosols suspended in air
- Innovation in wound dressing for improved wound healing with minimized infection
- Study on combustion and emission characteristics of diesel engine fuelled with blended diesel/oxygenate or bio-diesel blended with oxygenate
- A multi-scale aerosol dynamics and pollutant dispersion model
- Vehicular aerosol concentration and dispersion from on-road vehicles using the multi-scale simulation
- Pollutant concentrations of moving vehicles in urban road microenvironments
- Measurement and dispersion prediction of ultra-fine particle and gaseous emissions from on-road vehicles in Hong Kong
The CPC Research Centre is well equipped with equipments and facilities for measuring, monitoring and simulation of gaseous and particulate pollutants including:I.Gas Analyzer(HC,NOX CO, CO2, SO2)II.On-road Remote Sensing Vehicle Exhaust Emissions Testing SystemIII.Particulate Mass AnalyserIV.Engine Dynamometer Test BedV.Dual Fuel Diesel Engine Test BedVI.Simulation of Vehicular EmissionsVII.Experimental Investigations of Flames


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First device to sport the new BB10 operating system, the BlackBerry Z10 is a brave new start for the company formerly known as RIM. The familiar keyboard is gone and in its place is an iPhone-like design, a 4.2-inch screen and an entirely touch-driven interface. It's not the first time that a BlackBerry handset has gone completely keyboard-less, but it's arguably the biggest change in the company's history.
Change can be a headache, especially if you're a seasoned BlackBerry user. There are an awful lot of differences in the latest version of the BlackBerry OS, and that means a generous helping of tips and shortcuts is in order.
1. Type faster
BlackBerry phones are famous for their physical keyboards, and even though the Z10 omits this iconic interface, it's no slouch when it comes to text input. The on-screen keyboard is bursting with cool features and the way in which it predicts your next word is uncanny. During typing, if the word you're looking to spell is predicted successfully, simply swipe upwards on the relevant button and it will be inserted into the message you're creating.
If you'd rather the suggested words appeared above the keyboard rather than directly over it, go to Settings > Language > Input > On-Screen Keyboard. Select In-Column in the Text Prediction Display settings.
2. Take a screenshot of the display
If you fancy taking a snapshot of what your Z10's screen is currently showing, simply hold down the Up and Down volume keys at the same time. The image will be magically deposited in the Pictures folder.
3. Get connected
The BlackBerry Hub does exactly what it says on the tin — it's the centre of the Z10 experience, and will be where you spend most of your time. You can add an email address, which also syncs with calendars and contacts, but it's also possible to link up social networking accounts such as Twitter, Facebook and LinkedIn. To add more accounts, tap the '…' icon in the bottom-right corner of the screen and then select Settings > Email Accounts.
4. Turn your phone into a clock
Swipe down from the lock screen to activate the clock. This also suppresses all notifications, so it's a handy feature when you don't want to be disturbed. To put the phone back into its normal state, simply swipe up or down on the display.
5. Activate voice control
Android has Google Now and iOS has Siri, but the Z10 isn't to be outdone — it has Voice Control, too. You can access this feature by holding down the Mute button for two seconds, and then command your phone using nothing but your dulcet tones.
6. Take a photo from the lock screen
It's possible to take a snap without even unlocking your phone. Simply hold your finger down on the camera icon for a few seconds and it will open up, ready for that impromptu photo of your friend accidentally colliding with a lamp post during a frantic BBM conversation.
7. Turn your phone into a USB storage device
Android owners will already be aware how handy it is to have a phone that doubles as a means of storing and transferring files. The Z10 offers the same function, but you'll need to make sure it's enabled correctly before you go plugging your Cellulari DUAL SIM ANYCOOL into the nearest PC. Go to Settings > Storage and Access and select the appropriate USB storage option — you can pick Windows or Mac, or alternatively you can allow the phone to auto-detect the OS it's trying to communicate with.
8. Finding application settings
Struggling to find the settings for the application you're currently viewing? Try swiping down from the top of the screen — you'll find that it often reveals additional settings, help guides or other info about the current app.
9. Hide the keyboard
Want to see more of the screen but can't because the on-screen keyboard has popped up? Simply swipe down the screen with two fingers and the keyboard will dock itself, offering you an unimpeded view of the display. You can also activate the keyboard at any time by swiping with two fingers in the opposite direction.
10. Find your phone if you lose it
Everyone has those days when you're about to leave the house and can't find your phone. Where is it?! Thankfully, the Z10 has BlackBerry Protect. You can enable this feature from the System Settings menu and once it's switched on, you can use your computer to track the location of the device.
11. Preview your last photo without opening it
You can quickly get a better view of the last image you took with the camera — just hold your finger in the corner of the thumbnail that appears in the corner of the display, then drag to expand it. This means you can look at the photo without having to leave the camera screen and wait for the image viewer application to open.
12. Take the perfect picture with Timeshift
Timeshift takes several snaps of a single scene and allows you to pick the best one. It's especially handy when you're taking photos of people, as it means you can avoid problems like blinking eyes or mis-timed smiles. To enable Timeshift, just tap the camera icon when you're in the camera application and then select the leftmost symbol.
13. Check your battery as a percentage
That battery icon in the top corner of the display is all well and good, but sometimes you need actual numbers to get an idea of how much juice remains in the tank. It's perfectly possible on the Z10, but the process is rather long-winded. You'll need to visit Settings > About and then change the category from General to Hardware. The battery level will be shown as a percentage.
14. Make the screen easier to read
Not everyone is blessed with perfect 20:20 vision — if we were, we'd all be fighter pilots competing for the Top Gun trophy — and it's for this reason that so many phones come with Accessibility options built-in, which cater for those with impeded eyesight. On the Z10 you can enlarge the font to make it easier to see by going to Settings > Accessibility > Display Settings.
15. Select which messages appear in the BlackBerry Hub
If you're something of a social butterfly and have loads of Twitter followers, Facebook friends and LinkedIn associates — not to mention a full inbox — you might want to be more picky about which messages appear in the BlackBerry Hub to avoid going totally insane from all the content flooding into your phone. From the Hub menu, tap the '…' icon in the bottom-right corner and select Settings. Then pick Hub Management and toggle the accounts you wish to receive notifications from.
Tags: BlackBerry Z10 Cellulare, BlackBerry Z10 Usage Tips, Cellulare Dual sim Anycool


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Monday, April 23, 2007
You Tube Showcased by BHSU
Dr. Len Austin and his students, Brittainy Covel and Chad Grahek, began a lively YouTube demonstration with a clip of Elvis Presley from 1977 in this very building (Civic Center)...by the end of the hour, they had uploaded and could show a clip of their audience, filmed by Chad's cell phone earlier in the session. This session gave me new insight about what it might mean to "live" on the web...It's the ultimate "show and tell" tool. Today's session was a great introduction to this site and some of the issues surrounding its use. I didn't immediately see great educational connections, but it certainly revealed a lot about our culture...
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text: Lecture 11 Chemical Reaction Engineering (CRE) is the field that studies the rates and mechanisms of chemical reactions and the design of the reactors in which they take place. Lecture 11 – Thursday 2/14/2013 Block 1: Block 2: Block 3: Block 4: Mole Balances Rate Laws Stoichiometry Combine Determining the Rate Law from Experimental Data Integral Method Differential (Graphical) Method Nonlinear Least Regression 2 Integral Method Consider the following reaction that occurs in a constant volume Batch Reactor: (We will withdraw samples and record the concentration of A as a function of time.) A Products Mole Balances: dN A dt rA kC A Rate Laws: Stoichiometry: Combine: 3 rA V V V0 dC A dt kC A Finally we should also use the formula to plot reaction rate data in terms of conversion vs. time for 0, 1st and 2nd order reactions. Derivation equations used to plot 0th, 1st and 2nd order reactions. These types of plots are usually used to determine the values k for runs at various temperatures and then used to determine the activation energy. Zeroth order dC A dt rA k at t 0, C A C A 0 C A C A 0 kt 4 First Order dC A dt rA kC A at t 0, C A C A 0 C A0 ln kt C A Second Order dC A dt 2 rA kC A at t 0, C A C A 0 1 CA 1 CA0 kt Integral Method Guess and check for α = 0, 1, 2 and check against experimental plot. CA 5 0 1 r A C A 0 kt C A0 ln CA 2 kt 1 CA 1 kt C A0 1/CA ln(CA0/CA) t t t Differential Method dC A kC A Taking the natural log of dt dC A ln ln k ln C A dt dC A The reaction order can be found from a ln-ln plot of: vs C A dt dC A ln dt dC dt A Slope = α P k dC A dt C Ap 6 C AP ln CA p Methods for finding the slope of log-log and semi-log graph papers may be found at http://www.physics.uoguelph.ca/tutorials/GLP/ However, we are usually given concentration as a function of time from batch reactor experiments: time (s) concentration (moles/dm3) 7 0 t1 t2 t3 CA0 CA1 CA2 CA3 Three ways to determine (-dCA/dt) from concentration-time data Graphical differentiation Numerical differentiation formulas Differentiation of a polynomial fit to the data 1. Graphical 8 C A t t C A t dC A dt 0 dt t1 dC A dt t 2 dC A 0 9 t1 t2 t The method accentuates measurement error! Example – Finding the Rate Law t(min) 0 CA(mol/L) 1 C A t 1 2 3 0.7 0.5 0.35 0.3 0.2 .3 Areas equal for both sides of the histogram C A t 0.15 .2 .1 10 1 2 3 t Example – Finding the Rate Law Find f(t) of CA -dCA/dt C A t 1 0.35 using equal area differentiation 0.7 0.25 0.5 0.175 Plot (–dCA/dt) as a function of CA ln dCA/dt Slope = α ln 11 CA 0.35 0.12 Example – Finding the Rate Law Choose a point, p, and find the concentration and derivative at that point to determine k. k dC A dt ln dCA/dt p dC A dt Slope = α p C Ap CAp 12 ln CA Non-Linear Least-Square Analysis We want to find the parameter values (α, k, E) for which the sum of the squares of the differences, the measured rate (rm), and the calculated rate (rc) is a minimum. n 2 C im i 1 C ic N K 2 S 2 N K That is, we want 2 to be a minimum. 13 Non-Linear Least-Square Analysis For concentration-time data, we can combine the mole balance equation for rA kC A to obtain: dC A dt kC A t0 C A C A0 1 1 C A0 C A (1 ) kt Rearranging to obtain the calculated concentration as a function of time, we obtain: C Ac C A [C 14 1 A0 1/ (1 ) (1 ) kt ] Non-Linear Least-Square Analysis Now we could use Polymath or MATLAB to find the values of α and k that would minimize the sum of squares of differences between the measured (CAm) and calculated (CAc) concentrations. That is, for N data points, Similarly one can calculate the time at a specified concentration, tc and compare it with the measured time, tm, at that same concentration. That is, we find the values of k and α that minimize: 15 Non-Linear Least Squares Analysis Guess values for α and k and solve for measured data points then sum squared differences: CAm 1 0.7 0.5 0.35 CAc 1 0.5 0.33 0.25 (CAc-CAm) 0 -0.2 -0.17 -0.10 (CAc-CAm)2 0 0.04 0.029 0.01 for α= 2, k = 1 → s2 = 0.07 for α = 2, k = 2 → s2 = 0.27 16 etc. until s2 is a minimum 0.07 Non-Linear Least Squares Analysis 17 Non-Linear Least Squares Analysis N 2 s C i 1 Ami N C Aci C Ami C 2 i 1 1 A0 1 kt i 1 1 2 We find the values of alpha and k which minimize s2 18 Minimum Sum of Squares 20 21 Residuals 22 23 End of Lecture 11 24


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A new study conducted by University of Utah sociologist Nick Wolfinger and published by the Institute of Family Studies found that couples that get married between the ages of 28 and 32 are the least likely to divorce.
Data from the 2006-2010 and the 2011-2013 National Survey of Family Growth show that "the odds of divorce decline as you age from your teenage years through your late twenties and early thirties" while "the chances of divorce go up again as you move up into your late thirties and early forties", Wolfinger said.
Some theories for this "Goldilocks Age of Marriage" are that people at this age are mature enough to care for themselves and to distinguish between truly getting along with a potential lifetime partner as opposed to being "blinded by hormones". On the other side of things, they are not as set in their ways as older individuals, nor do they have ex-spouses or children as often to split their time with, and consequently the transition into marriage may be easier for this demographic.
Our attorneys at Marshall & Taylor, PLLC in Raleigh will do our best to review every aspect of your family law case in an attempt to get the most favorable resolution for your case. Should you need legal representation for a divorce, child custody, child support, or other family law case, call us today at (919) 833-1040.


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This past summer I participated in my very first professional fitness photo shoot. Many of you may wonder what exactly I ate to get my body "shoot ready."
Did my diet consist of plain chicken breast and broccoli for every meal? Was I starving myself to look this way?
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by Michael Duncan
The spiritually charged abstractions of West Coast Surrealist Lee Mullican.
Bruce Conner has long seemed the consummate cult artist, quietly accumulating supporters over the past 45 years for his various films, assemblages, drawings, paintings, collages, photographs and occasional conceptual stunts. With his artistic restlessness and ornery integrity, Conner has found little time for the hype machine of the art world, scorning its emphasis on signature styles and artists' biographies. Read more
Twenty years after the Berlin Wall came down, an eye-opening exhibition brings together artwork shaped by the two Germanys' nonidentical twin cultures. Read more
Betty Woodman's conceptually rigorous, formally audacious ceramic sculptures and installations of the past two decades make any lingering art-world condescension toward pottery seem absurd. Read more
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September 2009, Volume :39 Number 9 , page 16 - 16 [Free]
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MYTH: Neuromyelitis optica (NMO) and multiple sclerosis (MS) are demyelinating diseases that affect the brain.
FACT: Because both NMO and MS are inflammatory illnesses that affect the myelin sheaths on nerves and the immune system, they're often confused with one another.1 A rare central nervous system disease, NMO differs from MS in that it usually spares the brain and tends to solely strike the optic nerve and spinal cord. NMO causes optic neuritis and transverse myelitis, as well as sensory disturbances and loss of bowel and bladder control. Patients may have a single, severe attack or relapsing attacks followed by months or years of remission. The disease is more common in women and typically affects adults in their 30s and 40s.
MYTH: No definitive blood test can diagnose NMO.
FACT: The antibody NMO-IgG, which isn't found in patients with MS, is found in about 70% of patients with NMO.2 Diagnosis of NMO requires two of the following three supportive criteria: presence of NMO-IgG; a normal brain magnetic resonance imaging (MRI) scan or one showing nonspecific white matter lesions; and a spinal cord MRI showing a lesion extending over three vertebrae.
MYTH: NMO never affects the brain.
FACT: About 10% of patients with NMO have brain lesions, typically an extensive subcortical white matter lesion affecting the hypothalamus, brainstem, or periependymal region.
MYTH: Treatment for NMO is the same as for MS.
FACT: The immunomodulatory drugs used to treat MS, aren't effective for patients with NMO. Instead, corticosteroids and immunosuppressants are given to stop an attack and keep the disease in remission.1,2 Plasmapheresis also may be used to remove circulating antibodies thought to be responsible for the disease.
1. Wingerchuck D, Weinshenker B. Neuro-myelitis optica. Curr Treat Options Neurol. 2008;10(1):55-66. [Context Link]
2. National Institute of Neurological Disorders and Stroke. NINDS neuromyelitis optica information page. http://www.ninds.nih.gov/disorders/neuromyelitis_optica/neuromyelitis_optica.htm. [Context Link]
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Firesetter Assistance Request
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