text: Hi, I think it would be good if we came up with some general guidelines wrt the processes by which decisions are made. By ³decisions², I mean decisions that we, as a community, will try to abide by ? I have noticed in the past, that discussions in the mailing list (ML) sometimes peter out without a conclusion or decision. The ML seems to be a decent forum for discussion but not for decision making. At least, that¹s my impression so far. The (formal?) decision-making mechanisms we have are: - voting at our weekly ironic meeting. (When there is a vote, one can see who voted for what.) - In summit design sessions - in mid-cycles - via spec or code patches. if someone asks for more people to voice their opinion - anything else? We also tend to get consensus/agreement on IRC (if there are enough people present, where ³enough² typically means some number of core reviewers voicing their opinion). I have a few concerns about the above. The ones that come to mind right now: - I would like it to be possible to make decisions without everyone being present at the same time. Or if that isn¹t possible/do-able right now, at least let¹s make it clearer what a process might be, with some caveat for people-who-couldn¹t-attend to disagree later? - consensus/agreement on IRC is nice, but I think it needs to move beyond that to being recorded somewhere. (I think we are doing this via comments in patches and other means but I don¹t know for sure.) The reason I am bringing it up now (yes, the truth comes out) is because I asked a question on the mailing list on Monday [1] and it is now Thursday and maybe I am impatient ? I was about to reply to some of the comments and started to wonder whether it was worth replying or maybe it would be more effective (with respect to gathering the most feedback in the shortest amount of time) to move the discussion to our weekly meeting and hopefully have a decision then. (And the reason I even brought up that question was because I was reviewing someone¹s patch and it seemed like a good idea to try to unblock that patch instead of letting it languish there until someone else did something about it. But I digressŠ ?) So what do folks think? Should a process for not-critical-or-time-sensitive-issues be e.g.: - bring it up for discussion in the mailing list - after some elapsed amount of time (how long?) and/or petering out of replies, bring it up in some meeting for a decision? --ruby [1] http://lists.openstack.org/pipermail/openstack-dev/2016-May/095090.html


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McGregor can pass racist and Islamophobic insults, but Nurmagomedov can't react to it?
"Let's talk now", said Khabib Nurmagomedov, as his fists pounded Irish fighter Conor McGregor. In the ring, the Russian fighter humbles his opponent. Ten minutes later, the cocky Irishman taps out. The fight is over. The Russian has won it convincingly; an easy victory after a much hyped fight. But wait, the fight is apparently not over yet for the Dagestani fighter, also known as The Eagle. Despite a dominating victory, he is still angry. That anger needed only a nudge in the right (or wrong) direction, and that push was provided by McGregor's training partner Dillon Danis, who ...Read Full Post
The dark hope of freedom
They could clearly hear the sound of wailing from their neighbour's house. Another suspected freedom fighter was dead at the hands of the Indian army. Guilty or not, it didn't really matter and guilty of what? Ayaan thought. Of trying to free themselves from the evil tyrants? He glanced at his mother and saw her praying. Obviously praying for the safety of her family and for peace in Kashmir. His mother was a dreamer despite the hell she had been through but Ayaan himself had given up on hopes and dreams, all he focused on was blending in with ...Read Full Post
A conversation with the Falcon and his coach, Jeff Mayweather
On July 17, 2016, Pakistan's very own Muhammad Waseem will be taking on Philippine's Jether Oliva for the World Boxing Council (WBC) Silver Flyweight title. The belt is an interim world title of sorts and winning it will bring Waseem inches closer to a shot at the full WBC Flyweight World title. The genius behind securing this massive opportunity for Waseem is the Korean promoter, Andy Kim of AK Promotions, who has worked tirelessly and invested a fortune in developing Waseem into a proper title contender. I managed to contact Mr Kim via email to set up a telephone interview with Waseem. He was ...Read Full Post
Mixed Martial Arts: Pakistan versus Afghanistan – a 'patriotically personal' match!
In spite of there being many local wrestling akharas (training hall for martial artists) in Pakistan where desi pehlwan's dish it out, as well as a number of martial arts schools, a match between the two different styles of fighters was never heard of in the country. Being a fan of full contact sports, I found the recent decline in martial arts, kabbadi and wrestling events to be very disappointing. Growing up, I was used to watching these three sports on national TV but then it all faded into oblivion. On the other hand, in the rest of the world a new full contact sport was on the rise ...Read Full Post
1-4 of 4

subset: commoncrawl


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Persimmon Salad by Shoshannah HausmannUS
Read More...
This is a tasty savory persimmon salad that I often make for fall and winter gatherings. It's yummy! Serve it as is or over a bed of mixed salad greens.
Persimmon Smoothie by Katia BulbenkoWeehawken, NJ, US
Read More...
A delicious, healthy treat made with just 4 ingredients. You'll need the Fuyu variety of persimmon for this.
Late Night Fruit & Snacks by Jayde XuBaltimore, Maryland, US
Read More...
Growing up, my parents would always cut up fruit and de-shell nuts for us, as sort of a post-supper snack. My mother would carefully cut up chilled seasonal fruit and brew a pot of chrysanthemum tea. My father would use his own teeth to crack open salted peanuts and sunflower seeds for us, while frying up prawn crackers at the stove.
They're just simple cut fruit and nuts, but somehow they don't taste the same when I'm just preparing them by myself. That they are meticulous labors of love are what make them taste special.
*Completed for Rebecca Bradley's "Illustrating the Edible" course at MICA*
Yums up!
Illustrators for Hire
Need to commission an illustration? In search of fresh talent? Looking for artwork to license? Visit Illustrators for Hire to see our curated selection of freelance artists, designers and studios.
This week's featured illustrator:
Denise Ortakales
They Draw & Garden!
We have a new Instagram account dedicated to sharing beautiful garden inspired artwork. They Draw & Garden! We love blossoms, blooms, birds, bees, butterflies, branches, berries and bouquets. Tag us @theydrawandgarden or use #theydrawandgarden so we can see your work.
New Design Challenge!
The theme of our NEW HandPicked Design Challenge is GLOBAL CUISINE! It will be curated by Joy Aquilino, Editorial Director at Quarry Books and Rockport Publishers. Here are the details. Let's make this one big international party! Submissions due Dec. 17, 2019.
The TDAC Shop
Super excited about our collaboration with Amber Lotus Publishing! You can Pre-order the 2020 They Draw & Cook Calendar here. Twelve deliciously illustrated recipes from artists all around the world.
Visit our shop!
recently added recipes
Yaya's Manti Recipe by Maral VarolianQueens, New York, US
When I was a child my yaya was my world. I loved spending time with her and she was always in the kitchen. My fondest memory with her is making a special dish from our Armenian culture called Manti. It is a labor intensive dumpling soup from the Caucasus. The dish is a staple amongst Armenian families and all of my friend's yaya's make it. To make Manti you make the dough from scratch, roll it out thinly then cut it into squares. Once your squares are ready you stuff them with a meat mixture and then pinch them together. Then this is either boiled or baked in the oven before it is put in a bowl and topped with yogurt, and depending on where you are from either a red pepper or butter sauce. My yaya and I would bond over this recipe, my role only being pinching together the dumplings while she made the rest of the soup. I wanted to create a illustration that showed the steps for this dish, specifically focusing on the part that I would help her with.
Memorable Peanut Butter & Jelly Sandwiches-Fave Memory by Jacqueline GutierrezSaratoga, New York, US
Peanut butter and jelly sandwiches are simple and delicious. This was one of the first recipes that my mother showed me as a kid and one of the first recipes I shared with my own children.
Fave Memory - Affie's Potato Rolls by RandiPaceSan Jose, CA, US
These potato rolls are my Grandmother Affie's. We made these on special occasions, including Thanksgiving and Christmas. As I got older, it was my responsibility to make them while my grandmother, mom, and aunts made everything else. I always liked making them into a clover shape because I thought they looked fancier that way. My mom also makes cinnamon rolls to share on Christmas morning out of this dough. These were always my favorite.
Ouma Willa's Kitchen by Danelle van EedenWorcester, Western Cape, ZA
Favorite Food Memory
Fave Memory-Kaiyukan Aquarium by Khai Likuala lumpur, asia, MY
First time visiting an aquarium with our daughter, it's during our recent trip in Osaka. Greeted by a tunnel once entering. Enjoyed looking at variety of species available, magnificent views. We had a limited edition soft serve ice cream in the cafe. It's an unforgettable experience for us.
Food That Reminds me of My Grandparents by Kate MAustin, Texas, US
Fave Memory: It wasn't that my grandparents weren't good cooks, It's that my favorite food memories were simple ingredients that tasted good together and/ or sparked the imagination. Thanks for the opportunity!
Grandpa was magical! He made it snow. by la.iladeromaMilan, Italy, IT
Fave Memory - When I was a child and I used to have lunch with my grandparents it was always a joyful day.
Every Sunday the family met all together. Before starting to eat my grandpa used to take a handful of cheese and let it fall on the dish of pasta, saying "it's snowing!!!" A thin white layer appeared, and it started to melt due to the heat, just like snow. He used to repeat it every time, and every time I was enchanted by those flakes falling down softly.
Grate Expectations by Givi CarterAtlanta, GA, US
Fave Memory
A pretty cheesy interpretation of one of many favorite food memories from childhood (and adulthood).
Fantasy Fudge! by Judith MayerChicago, ILLINOIS, US
Fave Memory - I remember first making the recipe for Fudge from the label of the jar of Marshmallow Fluff jar in the 80s. You didn't need to worry about candy thermometers and getting just the right temperature with this recipe. It was simple and quick! It was the age of convenience...the microwave was used more than the oven in those days! (how do you like my "Miami Vice" colorway? Rad, right?!)
Mac And Cheese Memories (for busy parents) by Anne Was HereRedondo Beach, CA, US
"Fave Memory"
My dog sits right under my baby boy's high chair and watches for falling food like a hawk. One time she emerged from under the table with mac and cheese noodles stuck all over her head which made my kids die with laughter. It's one of those sweet memories I'll never forget! This recipe is for the busy mom or dad who wants less time spent cooking and a bit more quality time with their kids some evenings. It's a fool proof dinner that your kids are sure to love and you will love the quick prep time!


text:
Once again,great work.
I watched this and I loved it. It's great work that isn't scary. I love the application of black and white,and yet it still portrayed great detail and got the points across.The violence was pretty sweet,and I still love the crazy scene-hopping with the loud noises.The music was cool,and I actually felt sorry for that guy who was on the roof a lot.Poor poor guy.Yeah,like I said style just rocks..the graphics to,the sketchyness of it makes it look even more creepy. The only thing I did't quite get was that very last scene.The little splice after he falls off the roof.I was expecting something,it was just too peaceful...then I missed it.I'll be watching this again and again...Only one question,what's with the crows?


text:
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Scholarly Works (4 results)
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Peer Reviewed
Spinal myxopapillary ependymomas demonstrate a warburg phenotype
Mack, SC
Agnihotri, S
Bertrand, KC
Wang, X
Shih, DJ
Witt, H
Hill, N
Zayne, K
Barszczyk, M
Ramaswamy, V
Remke, M
Thompson, Y
Ryzhova, M
Massimi, L
Grajkowska, W
Lach, B
Gupta, N
Weiss, WA
Guha, A
Hawkins, C
Croul, S
Rutka, JT
Pfister, SM
Korshunov, A
Pekmezci, M
Tihan, T
Philips, JJ
Jabado, N
Zadeh, G
Taylor, MD
et al.
UC San Francisco Previously Published Works
© 2015 American Association for Cancer Research. Purpose: Myxopapillary ependymoma (MPE) is a distinct histologic variant of ependymoma arising commonly in the spinal cord. Despite an overall favorable prognosis, distant metastases, subarachnoid dissemination, and late recurrences have been reported. Currently, the only effective treatment for MPE is gross-total resection. We characterized the genomic and transcriptional landscape of spinal ependymomas in an effort to delineate the genetic basis of this disease and identify new leads for therapy. Experimental Design: Gene expression profiling was performed on 35 spinal ependymomas, and copy number profiling was done on an overlapping cohort of 46 spinal ependymomas. Functional validation experiments were performed on tumor lysates consisting of assays measuring pyruvate kinase M activity (PKM), hexokinase activity (HK), and lactate production. Results: At a gene expression level, we demonstrate that spinal grade II and MPE are molecularly and biologically distinct. These are supported by specific copy number alterations occurring in each histologic variant. Pathway analysis revealed that MPE are characterized by increased cellular metabolism, associated with upregulation of HIF1α. These findings were validated by Western blot analysis demonstrating increased protein expression of HIF1α, HK2, PDK1, and phosphorylation of PDHE1A. Functional assays were performed on MPE lysates, which demonstrated decreased PKM activity, increased HK activity, and elevated lactate production. Conclusions: Our findings suggest that MPE may be driven by a Warburg metabolic phenotype. The key enzymes promoting the Warburg phenotype: HK2, PKM2, and PDK are target-able by small-molecule inhibitors/activators, and should be considered for evaluation in future clinical trials for MPE.
Peer Reviewed
Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome
Panwalkar, P
Clark, J
Ramaswamy, V
Hawes, D
Yang, F
Dunham, C
Yip, S
Hukin, J
Sun, Y
Schipper, MJ
Chavez, L
Margol, A
Pekmezci, M
Chung, C
Banda, A
Bayliss, JM
Curry, SJ
Santi, M
Rodriguez, FJ
Snuderl, M
Karajannis, MA
Saratsis, AM
Horbinski, CM
Carret, AS
Wilson, B
Johnston, D
Lafay-Cousin, L
Zelcer, S
Eisenstat, D
Silva, M
Scheinemann, K
Jabado, N
McNeely, PD
Kool, M
Pfister, SM
Taylor, MD
Hawkins, C
Korshunov, A
Judkins, AR
Venneti, S
et al.
UC San Francisco Previously Published Works
© 2017, Springer-Verlag GmbH Germany. Posterior fossa ependymomas (EPN_PF) in children comprise two morphologically identical, but biologically distinct tumor entities. Group-A (EPN_PFA) tumors have a poor prognosis and require intensive therapy. In contrast, group-B tumors (EPN_PFB) exhibit excellent prognosis and the current consensus opinion recommends future clinical trials to test the possibility of treatment de-escalation in these patients. Therefore, distinguishing these two tumor subtypes is critical. EPN_PFA and EPN_PFB can be distinguished based on DNA methylation signatures, but these assays are not routinely available. We have previously shown that a subset of poorly prognostic childhood EPN_PF exhibits global reduction in H3K27me3. Therefore, we set out to determine whether a simple immunohistochemical assay for H3K27me3 could be used to segregate EPN_PFA from EPN_PFB tumors. We assembled a cohort of 230 childhood ependymomas and H3K27me3 immunohistochemistry was assessed as positive or negative in a blinded manner. H3K27me3 staining results were compared with DNA methylation-based subgroup information available in 112 samples [EPN_PFA (n = 72) and EPN_PFB tumors (n = 40)]. H3K27me3 staining was globally reduced in EPN_PFA tumors and immunohistochemistry showed 99% sensitivity and 100% specificity in segregating EPN_PFA from EPN_PFB tumors. Moreover, H3K27me3 immunostaining was sufficient to delineate patients with worse prognosis in two independent, non-overlapping cohorts (n = 133 and n = 97). In conclusion, immunohistochemical evaluation of H3K27me3 global reduction is an economic, easily available and readily adaptable method for defining high-risk EPN_PFA from low-risk posterior fossa EPN_PFB tumors to inform prognosis and to enable the design of future clinical trials.
Peer Reviewed
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
Pajtler, KW
Witt, H
Sill, M
Jones, DTW
Hovestadt, V
Kratochwil, F
Wani, K
Tatevossian, R
Punchihewa, C
Johann, P
Reimand, J
Warnatz, HJ
Ryzhova, M
Mack, S
Ramaswamy, V
Capper, D
Schweizer, L
Sieber, L
Wittmann, A
Huang, Z
van Sluis, P
Volckmann, R
Koster, J
Versteeg, R
Fults, D
Toledano, H
Avigad, S
Hoffman, LM
Donson, AM
Foreman, N
Hewer, E
Zitterbart, K
Gilbert, M
Armstrong, TS
Gupta, N
Allen, JC
Karajannis, MA
Zagzag, D
Hasselblatt, M
Kulozik, AE
Witt, O
Collins, VP
von Hoff, K
Rutkowski, S
Pietsch, T
Bader, G
Yaspo, ML
von Deimling, A
Lichter, P
Taylor, MD
Gilbertson, R
Ellison, DW
Aldape, K
Korshunov, A
Kool, M
Pfister, SM
et al.
UC San Francisco Previously Published Works
© 2015 Elsevier Inc. Ependymal tumors across age groups are currently classified and graded solely by histopathology. It is, however, commonly accepted that this classification scheme has limited clinical utility based on its lack of reproducibility in predicting patients' outcome. We aimed at establishing a uniform molecular classification using DNA methylation profiling. Nine molecular subgroups were identified in a large cohort of 500 tumors, 3 in each anatomical compartment of the CNS, spine, posterior fossa, supratentorial. Two supratentorial subgroups are characterized by prototypic fusion genes involving RELA and YAP1, respectively. Regarding clinical associations, the molecular classification proposed herein outperforms the current histopathological classification and thus might serve as a basis for the next World Health Organization classification of CNS tumors.
Peer Reviewed
Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma
Zhukova, N
Ramaswamy, V
Remke, M
Pfaff, E
Shih, DJH
Martin, DC
Castelo-Branco, P
Baskin, B
Ray, PN
Bouffet, E
Von Bueren, AO
Jones, DTW
Northcott, PA
Kool, M
Sturm, D
Pugh, TJ
Pomeroy, SL
Cho, YJ
Pietsch, T
Gessi, M
Rutkowski, S
Bognar, L
Klekner, A
Cho, BK
Kim, SK
Wang, KC
Eberhart, CG
Fevre-Montange, M
Fouladi, M
French, PJ
Kros, M
Grajkowska, WA
Gupta, N
Weiss, WA
Hauser, P
Jabado, N
Jouvet, A
Jung, S
Kumabe, T
Lach, B
Leonard, JR
Rubin, JB
Liau, LM
Massimi, L
Pollack, IF
Ra, YS
Van Meir, EG
Zitterbart, K
Schüller, U
Hill, RM
Lindsey, JC
Schwalbe, EC
Bailey, S
Ellison, DW
Hawkins, C
Malkin, D
Clifford, SC
Korshunov, A
Pfister, S
Taylor, MD
Tabori, U
et al.
UCLA Previously Published Works
© 2013 by American Society of Clinical Oncology. Purpose: Reports detailing the prognostic impact of TP53 mutations in medulloblastoma offer conflicting conclusions. We resolve this issue through the inclusion of molecular subgroup profiles. Patients and Methods: We determined subgroup affiliation, TP53 mutation status, and clinical outcome in a discovery cohort of 397 medulloblastomas. We subsequently validated our results on an independent cohort of 156 medulloblastomas. Results: TP53 mutations are enriched in wingless (WNT; 16%) and sonic hedgehog (SHH; 21%) medulloblastomas and are virtually absent in subgroups 3 and 4 tumors (P < .001). Patients with SHH/TP53 mutant tumors are almost exclusively between ages 5 and 18 years, dramatically different from the general SHH distribution (P < .001). Children with SHH/TP53 mutant tumors harbor 56% germline TP53 mutations, which are not observed in children with WNT/TP53 mutant tumors. Five-year overall survival (OS; ± SE) was 41% ± 9% and 81% ± 5% for patients with SHH medulloblastomas with and without TP53 mutations, respectively (P < .001). Furthermore, TP53 mutations accounted for 72% of deaths in children older than 5 years with SHH medulloblastomas. In contrast, 5-year OS rates were 90% ± 9% and 97% ± 3% for patients with WNT tumors with and without TP53 mutations (P = .21). Multivariate analysis revealed that TP53 status was the most important risk factor for SHH medulloblastoma. Survival rates in the validation cohort mimicked the discovery results, revealing that poor survival of TP53 mutations is restricted to patients with SHH medulloblastomas (P = .012) and not WNT tumors. Conclusion: Subgroup-specific analysis reconciles prior conflicting publications and confirms that TP53 mutations are enriched among SHH medulloblastomas, in which they portend poor outcome and account for a large proportion of treatment failures in these patients.


text:
Hello Aspirants,
Welcome to Online Quant Section in AffairsCloud.com. We are starting IBPS Clerk course 2015 and we are creating sample questions in Reasoning section, type of which will be asked in IBPS Clerk Main Exam.
Stratus – IBPS Clerk Course 2015
Directions (1 – 5): In each of the questions below, statements are given followed by three conclusions numbered I, II, and III. You have to take the given statements to be true, even if they seem to be at a variance with commonly known facts. Read all the conclusions and then decide which of the given conclusions logically follows from the given statements, disregarding commonly known facts.
- Statements: Some pages are plants. All pages are sheets. No plant is style. All clips are styles.
I. Some plants are clips is a possibility.
II. All pages are clips is a possibility.
III. No clip is plant.
A) Only I and III follow
B) Only III follow
C) Only II and III follow
D) Only I follow
E) None follow
- Statements: All squares are circles. All triangles are squares. Some pots are circles. All suits are circles.
I. Some circles are not triangles.
II. Some suits being squares is a possibility.
III. Some suits are pots.
A) Only III follow
B) Only I and II follow
C) Only II and III follow
D) Only II follow
E) Only I follow
- Statements: Some plants are trees. All trees are flowers. All flowers are petals. No stem is flower.
I. Some stems are trees is a possibility.
II. All stems being petals is a possibility.
III. Some plants are flowers.
A) None follow
B) Only I and III follow
C) Only I follow
D) Only II follow
E) Only II and III follow
- Statements: No square is rectangle. All rectangles are circles. Some triangles are squares. Some circles are triangles.
I. No square is circle.
II. All triangles being rectangles is a possibility.
II. All circles being squares is a possibility.
A) Only I follow
B) All follow
C) Only I and II follow
D) Only II follow
E) None follow
- Statements: All views are reviews. No review is space. Some spaces are roofs. Some mails are reviews.
I. All spaces being mails is a possibility.
II. All mails being roof is a possibility.
III. No space is view.
A) Only III follow
B) Only I and III follow
C) Only II and III follow
D) Only II follow
E) All follow
Directions (Q. 6-10): Study the following information to answer the given questions:
Each of the 6 friends – A, B, C, D, E, and F wears a different branded shirt among Polo, Reebok, Adidas, Gap, Milan and Lava of six different colors among Red, Blue, Green, White, Pink and Black not necessarily in the same order.
C wears a red color short which is neither Polo nor Lava. A wears Reebok shirt which is neither black nor pink in color. Either E or F wears white shirt. B wears Gap shirt which is not pink in color. D wears either Adidas or blue shirt. E wears blue shirt which is not Lava.
- Who wears black shirt?
D) B or D
E) Data inadequate
- Of which brand is F's shirt?
A) Milan
B) Adidas
C) Polo
D) Lava
E) Data inadequate
- Which of the following is true?
A) C wears Adidas
B) Lava is in white color.
C) Adidas is not in pink color
D) D wears blue.
E) None above is true
- Which of the following is correctly matched?
A) Blue – Adidas
B) Pink – Reebok
C) Red – Milan
D) Black – Lava
E) Red – Polo
- The Gap shirt is in which color?
A) Green
B) White
C) Blue
D) Data inadequate
E) None of these


text:
We are a large-scale manufacturer specializing in producing various mining machines including different types of sand and gravel equipment, milling equipment, mineral processing equipment and building materials equipment. And they are mainly used to crush coarse minerals like gold and copper ore, metals like steel and iron, glass, coal, asphalt, gravel, concrete, etc. With more than 2,500 case sites, the scientific management method, the refined manufacturing process, and the innovative manufacturing concept,have rapidly grown into the mining machinery production and export bases in China even the world.
2019722 PEW Jaw Crusher. PEW Jaw Crusher is a new crushing machine developed by SBM the jaw crusher manufacturer after the release of traditional jaw crusher. This jaw crusher is a perfect combination of modern science and technology and the production practice which can better satisfy the automatic production demands of vast customers.Read More
2019716 Jaw crusher is an important primary crushing equipment in mining industry. Besides price and quality its parts installation and replacement are also attractive to users. Jaw crusher is an important primary crushing equipment in mining industry. Besides price and quality its parts installation and replacement are also attractive to users.Read More
Jaw Crusher Jaw Crusher JC5 Applicationhardbrittle sample Such asmineral coal.glassferrovanadium alloy Jaw Crusher JC6 Applicationhardbrittle sample Such asoreRead More
2019528 The Jaw crusher is used for Primary crushers and Secondary crushers for crushing all kinds of minerals and rocks with compressive strength less than 320 mpa. There are two types of Jaw crushercoarse jaw crusher and fine jaw crusher.Read More
Jaw Crusher Maintenance. It is well known that jaw crusher is the most commonly used primary crushing equipment in crushing plants. In the Read More. Jaw Crusher Capacity Parameter. Todays SBM jaw crushers achieve an even higher standard both in industryleading productivity and uptime availabilityRead More
Jaw crusherjaw crusherjaw crusherjaw crusherjaw crusherjaw crusherRead More
We are committed to producing the very best in specialied mining and rock excavation equipment. Our pioneering mobile jaw crusher series is a powerful example. Whatever the application Sandvik heavy duty jaw crushers are designed to deliver increased levels of productivity while maximiing operator comfort and bottomline cost efficiency.Read More
Jaw crusher Track drives. Track drives Bonfiglioli solutions for tracked jaw crushers are compact yet deliver high performance. The wide variety of ratio combinations allows our solutions to offer the best possible efficiency. Discover products . Download documentsRead More
Circuit includes feed bin and belt feeder 600X400 single toggle jaw crusher 1000X700 impact crusher 16X5 twin deck vibrating screen 10X4 twin deck vibrating screen self cleaning electro magnet picking line conveyor air blowers 7 X belt conveyors Ready for.Read More
Pronex is passionately engrossed in this occupation of wholesale trading since 2016.Our firm is a sole proprietor owned entity which is headquartered at Tambaram West Chennai Tamil Nadu.The spectrum of products in which we deal includes Jaw Crushers Crusher Plants Turnkey Project Suspended Magnetic Separator Crusher Spares Parts and much more.Read More
2019613 Jaw Crusher Working Principle The motor drives belt and belt wheel the eccentric shaft causes the movable jaw to move down and up forward and backward the angle between toggle plate and movable jaw becomes bigger when the movable jaw moves up so that the movable jaw moves toward the fixed jaw and the materials are pressed crushed or cut as a result the aim of crushing isRead More
Shanghai Yike Road Bridge Machinery Co. Ltd. Experts in Manufacturing and Exporting jaw crusher spare parts impact crusher accessories and 155 more Products. ARead More
2019718 Lean design For higher quality only C6X series jaw crusher boast more reasonable moment of inertia and greater crushing strokes through optimiation of the equipment structure and crushing cavity type as well as the motion trail and speed parameters of the movable jaw able to achieve higher crushing efficiency at the same power consumption and thus offer customers a larger rate of return onRead More
2019624 Jaw Crusher Capacity 1700 th Applicable Material Jaw crusher is a kind of stone crushing machine which is widely used as primary or secondary crusher. Baichy manufactures coarse jaw crusher and fine jaw crusher in stationary type or mobile type.Read More
Jaw Crushers. Overview. Terex® Finlay tracked mobile jaw crushers are renown for their capabilities in the reduction and siing of aggregates for construction materials and also recycling construction waste. The Finlay range of jaw crushers are designed to meet the toughest demands of primary crushing applications with their impressive powerRead More
Business listings of Jaw Crusher manufacturers suppliers and exporters in Nashik जॉ क्रशर विक्रेता नासिक Maharashtra along with their contact details address. Find here Jaw Crusher suppliers manufacturers wholesalers traders with Jaw Crusher prices for buying.Read More
2019423 ASD Series Jaw Crusher is the new generation of jaw crusher with optimied and developed design which is based on absorbing the international advanced technology. Compared with the equivalentsie crusher ASD jaw crusher exceeds with better capacity bigger crushing ratio lower running cost as well as the friendly stable and reliable operation.Read More
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Name Origins
Ask questions here about the history and origin of surnames and given names.
Asked in Christmas, Name Origins
What is the origin of the name Christmas?
The Greek letter 'X' is the first letter (chi) for the greek word for Christ, Xristos ( Χριστός). Xmas therefore means "Christ's Mass." The letter chi is written the same as the Roman letter X. So, as a form of shorthand, some people replace "Christ" with the first letter of his Greek name, X. The term Xmas, while sometimes controversial among Christians, has become a common short English abbreviation for Christmas.
Asked in Name Origins, Definitions
Manhandled is it considered a form of abuse?
Asked in Militaria, Video Games, Name Origins, A Tale of Two Cities
Why do army officers peak caps have two golden threads?
Answer Peaked or visor caps usually have a loose-fitting strap that sits on top of the bill. This strap is attached at each side with a button. For officers, this strap can be a gold or silver "rope" and usually doubled. The visor cap evolved from earlier forms of military hats. All hats had a chin strap to help hold the hat firmly on the head. Officer's hats evolved to have a brass strap or over-lapping plates. Also, when not in use, the straps could be tied or buckled so that it was worn above the bill. Some even attached to the very top of the hat. A close comparison is the German pickelhaulbe (or spiked) helmet, which was a leather helmet first worn in the early 1800's. These were usually worn with the chin strap resting on the bill of the helmet. Enlisted men's helmets had leather chin straps and officer or elite troops(cavalry) had brass chin straps. So, the golden threads are actually chin straps. And they still function, some what, as an adjustable strap. The knot at each end will actually slide such that the strap will gown wide enough to place under the chin. But of course, there is no way to secute it snugly and it is not practical nor does it look cool, either. Another hat that also hat gold or colored cords were the Slouch hats worn by US Army. These resemble the common "cowboy hat". They were common wear during American Civil War and out West. A tan version was issued during the Spanish American War and later evolved into the Campaign Hat that Army drill instructors wore. These had a double cord that had two ends that hung loose. These were colored to indicate branch of service. I think this evolved to the colored piping worn on the Overseas caps used in WW2. British hat from Waterloo with white braided cord British hat from Waterloo era with chin strap tied up to peak of hat. French Napoleonic hats British shako (post Napoleonic) with 1-piece chin strap attached across front of hat. US Slouch hats and Campaign hats and other hats from various times. WW2 USAAF 'crusher' caps Soviet Visor caps Practical Answer The modern visor cap has the chin strap usually worn on top of the bill. Officers are rope cords and enlistedmen's are leather straps. Both are made of two strands, one attached at each button on the side of the hat. The cord wraps around the front of the hat and has a loop or knot at the other end that slips over the mating cord. This arrangement allows the chin strap to be loosened or tightened. This double cord design allows for this adjustment of the strap. The slouch hats also have double cords probably for the same reason. Custermen
Asked in Christmas, Name Origins
What is Grinch Mean Time?
The moment on the Grinchs' clock that indicates it's time to steal Christmas, and time to get mean. The answer above is almost certainly the right one, but it is just possible that the questioner was asking about Greenwich mean time. Many who don't speak the Queen's English believe that Greenwich is pronounced "green witch." Almost all Brits say it 'grennitch', but a few (including Her Majesty), opt for "grinnitch." New Zealanders, who long ago abandoned "maj-speak", go for 'grinnertch'. The 'er' in this is a very short schwa, and the result sounds amazingly like Grinch.
Asked in Name Origins, Names and Name Meanings
What is the meaning of the name Anisha?
Anisha signifies continuum and uninterrupted perpetual process that never stops, one which has an everlasting flame for eternity. Anisha is also one of the names of Goddess Laxmi, in Indian culture and mythology. Anisha is also an anagram of Ahinsa (i.e. non-violence). It may also mean "light" and "brightness" as in the opposite of night (i.e. "nisha" that signifies darkness). In that regards, the name Anisha carries the same meaning as another Indian name Usha. It is also believed that the name Anisha is dderived from Greek word Anice, and hence has the meaning Satisfaction or Fulfillment in material sense or Enlightenment in spiritual perspective. Notable Anisha: Anisha Nicole, Anisha Shenai, Anisha Nagarajan, Anisha Lakhani, Anisha Tomlinson, Anisha Khatkhate, Anisha Shenai-Khatkhate, Anisha Chinoy This name means she has the greatest power of all, invincible, blessed, lucky and one of gods greatest creations. This name brings luck and beauty to all it is a femanine name and originates from India. it was created by the king of india when his eldest daughter was born.
Asked in Sikhism, Name Origins, Caste System
What Sikh caste is the last name Kamyotra?
Asked in Name Origins, Sikhism, History of India
Is Bisla a jatt last name?
yes it is !! this caste belongs to jatt or jaat (as many live in haryana now) they were mainly from Punjab but as they have chosen to stay in native places.. they can be found in haryana , uttar pradesh & rajasthan as well.... their presence is also there in many foreign countries.... they have established their names in various parts of the world...
Asked in Name Origins, Surnames
Is Dennis an Irish surname?
The Dennis families of County Cork may have been Ó Donnghusa who anglicized their surname. The English surname Dennis is first found in the records of Lancashire, after the Norman Conquest that began in 1066 A.D. The French version of this surname is first found in Champagne, where they'd held family seat since the most ancient of days. See the Related Link listed below for more information:
Asked in Literature and Language, Name Origins
Where did the name Ludmilla come from?
Ludmilla, or more commonly, outside of English-speaking countries, Ludmila or Lyudmila, is a girl's name of Slavic origin (Bulgaria, Czech Republic, Poland, Hungary, Slovakia, etc.). Lud means "people," while mila means "love, dear," making Ludmila mean "love of the people." Perhaps the most famous person named Ludmila is Saint Ludmila, a Bohemian princess of the 10th century. She is known as the patron saint of Bohemia, the Czech Republic, religious converts, widows, and duchesses.
Asked in Christmas, Name Origins, English to Swedish
Where does the name Christmas come from?
Asked in Name Origins, Names and Name Meanings
What is the meaning of the name Weaver?
Asked in Chicago, Chicago Cubs, Name Origins
How did Chicago get its name?
The town of Chicago was founded in 1833 and named by the French Canadians in their pronounciation and spelling of an Algonquian word. It is either the Fox tribe's word for "place of wild onion" or the Ojibwa tribe's word for "skunk". Either way, it has been recorded that wild onion, chives and garlic grew in the area and the Chicago River was named for the plants and their fragrance. Then the city that was built on the river was called by the same name.
Asked in Home & Garden, Plants and Flowers, Name Origins
What is another name for a windflower?
Asked in Name Origins, Names and Name Meanings
A person's name meaning right hand of god?
Asked in Name Origins
What does Blue Ivy mean?
Blue from Jay-Z's successful CD hits (The Blue Print One, The Blue Print Two, The Blue Print Three, The Blueprint four and five). Ivy actually stand for the Roman Numeral IV, which means four. Jay-z and Beyonce were both born on the fourth, and they got married on the fourth. And, Carter is Shawn's last name. Beyond that, it means absolutely nothing; backwards, forwards or inside out it is meaningless to anyone other that little Blue Ivy and her parents.
Asked in Word and Phrase Origins, Name Origins
Where did the word 'kitchen' come from?
Asked in Quran (Koran), Name Origins, Baby Names, Sanskrit
What is meaning of Ayaan?
Name: Ayaan Meaning: Gift of God Gender: Male Origin: Arabic Ayaan word is mentioned in Surah al naml(ants) verse number 65 in the holy Quran it means the day of judgment , also the Arabic meaning is gift of god its also a sanskrit word meaning speed. Günther Schlee seems to translate ayaan as "day." (Chapter: "Loanwords in Oromo and Rendille as a mirror of past inter-ethnic relations." Book: African Languages, Development and the State. Page 201. 1994.) Mohamed Diriye Abdullahi says, "Ayaan means good luck and destiny, someone who is in good luck and prosperous might be referred to as ayaanle. Ayaan is also a popular name for girls. In the ancient Cushitic religion, the ayaan, or ayana among the Oromo, are good spirits or angels that mediate between god and humans and whose blessings one seeks. As is known from practices among non-Muslim non-Christian Oromo, the chief priest of the Cushitic cult is the qallu." (Book: Culture and Customs of Somalia. Page 65. 2001.)
Asked in Name Origins, Hemispheres
In which hemispheres is Asia located?
Asked in Name Origins
What is the origin of the name 'Kamisha'?
Asked in Word and Phrase Origins, Name Origins
What is the origin of the word calendar?
Asked in Name Origins
Where did the name Yossarian originate from?
Yossarian is an Armenian surname, a patronymic of uncertain origin. Other Armenian surnames, (answered from ancestry.com) Grigorian - Armenian: patronymic from the Armenian personal name Grigor (see Gregory). Hovespian - Armenian: patronymic from the personal name Hovsep, classical Armenian Yovsep (see Joseph).


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Continuous Subcutaneous Hydrocortisone Infusion In Addison`s Disease and Type 1 Diabetes
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01840189
Recruitment Status : Completed
First Posted : April 25, 2013
Last Update Posted : February 1, 2017
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
The conventional glucocorticoid replacement therapy in primary adrenal insufficiency (Addison's disease) renders the cortisol levels unphysiological, which may cause symptoms and long-term complications.
The majority of Addison's patients have other organ-specific autoimmune disease, which poses challenges to the replacement therapy. Of particular interest is the combination of Addison`s disease and type 1 diabetes, since cortisol affects glucose homeostasis. The clinical experience is that this subgroup of patients is difficult to treat, but very little research has been done to understand and improve their situation.
Glucocorticoid replacement is technically feasible by continuous subcutaneous hydrocortisone infusion, and can mimic the normal diurnal cortisol rhythm. This pilot study aims to further evaluate continuous subcutaneous hydrocortisone infusion treatment in terms of metabolic effects especially glycemic control in patients with the combination of Addison`s disease and type 1 diabetes in an 5 months cross-over design open clinical pilot study.
|Condition or disease
|Addison Disease Type 1 Diabetes
|Other: Cortef Other: Solu-cortef
|Phase 2
Hide Detailed Description
Treatment of Addison`s disease includes glucocorticoid and mineralocorticoid replacement. Despite optimized therapy with these steroids, many patients suffer from impaired quality of life and increased mortality. The etiology of the premature death is complicated and may include a combination of inadequate treatment of adrenal crisis, patient non-compliance, and undetected hypoglycemia, in addition to being associated with increased cardiovascular, malignant, and infectious disease deaths. The relative risk of death for patients with Type 1 Diabetes is 3.8 in Sweden. Having Type 1 diabetes and Addison`s disease significantly increased the risk of death when compared with having adrenal insufficiency alone. The risk for premature death in patients with the combination of Type 1 diabetes and Addison`s disease has not been extensively studied and appears to contribute to a small portion of the increased mortality seen in patients with Addison`s disease.
Cortisol has particularly potent effects on blood glucose levels, otherwise Addison`s disease affects the production of cortisol, an important counterregulatory hormone for hypoglycaemia. Lack of cortisol might increase the risk of hypoglycemic episodes, whereas over-replacement might cause hyperglycemia. Because steroid replacement may cause significant insulin resistance, it is challenging to adjust insulin doses to maintain optimal glycemic control. Little is known about the effects of unphysiological glucocorticoid replacement therapy on glucose and lipid metabolism, but there has been concern about long-term metabolic consequence. Current glucocorticoid replacement results in large fluctuations in the cortisol levels directly influencing glucose homeostasis and, consequently, making accompanying insulin treatment difficult to manage. Different types, regimens and doses of glucocorticoids are now used in adrenal insufficiency, but none approximate the physiological rhythm. Hydrocortisone administration via a subcutaneous pump is a novel strategy that restores circadian cortisol rhythm in most patients.
The study will be open-labelled, cross-over designed, with comparison of two glucocorticoid replacement modalities to glycemic events in randomised order within each patient, as illustrated in figure.
Treatment A is optimised oral hydrocortisone ( Cortef 5 mg) replacement according to Mah et al, and treatment B is continuous subcutaneous hydrocortisone infusion therapy. The patients will be assigned a participation number and randomised to any of two treatment sequences (A-B or B-A). Should the need for an extra glucocorticoid dose occur (intercurrent illness, exercises) during the study, for safety reasons, the patients should administer their previous glucocorticoid and insulin replacement. If the dose of insulin is changed, new testing by self-monitoring of blood glucose and continuous glucose monitor system should be done.
The period of dose adjustments for insulin treatment during both glucocorticoids replacement modalities will take 2 weeks for each and 6 weeks assessment of glycemic control by continuous glucose monitor system, followed by a minimal of one month during which the patients use their previous glucocorticoid replacement and previous insulin therapy (wash-out period).
Patients will be educated in groups, and dose adjustments will be co-ordinated with regular visits at the outpatient clinic/telephone consultation combined with laboratory analyses. After the principal study period participants will be offered a 3 months' continuous subcutaneous hydrocortisone infusion treatment extension period. Infusion gear and Solu-Cortef 50mg/ml infusate will be refunded over the study budget. Hydrocortisone infusion will be given as Solu-Cortef Act-o-Vial 50mg/ml produced by Pfizer. Pump designed for subcutaneous insulin infusion can be used for subcutaneous administration.
glucose levels are stable.
Withdrawal criteria/Adverse Events The patient is free to withdraw at any time. If a patient is having major difficulties managing the infusion pump/equipment/continuous glucose monitor after thorough education and instructions, the investigator will consider withdrawal. In the best interest of the patient, the investigator and the sponsor can decide to withdraw the patient from the study. Compliance of the patients will be checked according to the report from remote control - Patients Diabetes Manager and continuous glucose monitor. Unfortunately, there are available no methods how to follow up the compliance to the oral treatment. If a patient develops conditions meeting the exclusion criteria, the patient will be withdrawn from the study. In case of serious adverse events the patient may be withdrawn from the study.
Any adverse event will be registered and reported to the Norwegian and Swedish Medicines Agency. Any serious adverse events will be reported within 15 days, and in case of lethal or life threatening events immediately. The patients will report any problems or discomfort in the patient diary, any need for extra doses with glucocorticoids will also be documented there. In addition, we ask them to contact the study group directly in case of problems/adverse events between consultations.
The study documentation and research date will be stored 15 years after the termination of the study. After the termination of the study we will notify ethical committee by 90 days and the final report will be prepared and delivered to ethical committee. If needed to terminate the study earlier, we will notify the ethical committee by 15 days.
Statistical considerations The studies are academic, investigator-driven pilot studies, limited in number by expensive techniques and rare diseases.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|2 participants
|Intervention Model:
|Crossover Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|Continuous Subcutaneous Hydrocortisone Infusion In Addison`s Disease and Type 1 Diabetes
|Study Start Date :
|May 2013
|Actual Primary Completion Date :
|December 2016
|Actual Study Completion Date :
|December 2016
Active Comparator: Cortef
Treatment A is oral hydrocortisone replacement( Cortef 5 mg)with weight-adjusted doses as suggested by Mah et al , will take 2 months
Other: Solu-cortef
Treatment B is continuous subcutaneous hydrocortisone infusion with the initial standard dose of 10mg/m2/24hrs. Body surface area will be calculated according to the nomogram from the formula of Du Bois and Du Bois.
This part of the study will take 2 months.
Active Comparator: Solu-cortef
This is the treatment B by continuous subcutaneous hydrocortisone infusion. Solu-cortef infusion will be given as Solu-Cortef Act-o-Vial 50mg/ml, , produced by Pfizer. Pump designed for subcutaneous insulin infusion can be used for subcutaneous administration.
Other: Cortef
Treatment A is oral hydrocortisone replacement ( Cortef 5 mg) administered according to weight-adjusted doses for 2 months
- nocturnal hypoglycemic events [ Time Frame: 4 months ]severe hypoglycemia (needs for another person's assistance, blood glucose ≤ 3.1 mmol ⁄ L or prompt recovery after oral carbohydrate, i.v glucose or glucagon administration) and insulin requirement
- o Nocturnal glycemic variability [ Time Frame: 4 months ]monitored by continuous glucose monitor system
- hormone and metabolic profile [ Time Frame: 4 months ]
- Hormone levels : insulin like growth factor 1, growth hormone
- Steroid metabolism: adrenocorticotropic hormone , cortisol
- Metabolic profile: fructosamine, HBA1C, lipid levels, C reactive protein , homeostasis model assessment index
- o Subjective health status [ Time Frame: 4 months ]Self administration of questionnaires
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years to 70 Years (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- primary Addison`s disease in combination with long-standing Type 1 diabetes
Exclusion Criteria:
- cardiovascular disease
- active malignant disease
- pregnant women
- pharmacological treatment with glucocorticoids or drugs that interfere with cortisol metabolism (antiepileptics, rifampicin, St. Johns war, estrogens)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01840189
|Haukeland University Hospiatl
|Bergen, Norway, 5021
|Study Director:
|Kristian Løvås, MD, PhD
|Haukeland University Hospital
|Principal Investigator:
|Katerina Simunkova, PhD
|Haukeland University Hospital
Additional Information:
|Responsible Party:
|Haukeland University Hospital
|ClinicalTrials.gov Identifier:
|NCT01840189 History of Changes
|Other Study ID Numbers:
2012/005516-26 ( EudraCT Number )
|First Posted:
|April 25, 2013 Key Record Dates
|Last Update Posted:
|February 1, 2017
|Last Verified:
|December 2016
Addison disease
Type 1 diabetes
Diabetes Mellitus
Diabetes Mellitus, Type 1
Addison Disease
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Autoimmune Diseases
Immune System Diseases
Adrenal Insufficiency
Adrenal Gland Diseases
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Hydrocortisone hemisuccinate
Anti-Inflammatory Agents


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Graymatter SEO Tampa If you're searching for a Tampa SEO company to drive traffic to your website, then you've landed in the right spot. We specialize in driving targeted traffic. It's important to have a company like Graymatter SEO on your side that is familiar with your territory and location. More importantly, it's about being able to achieve results in such a competitive industry. Organic traffic can bring a tremendous amount of business to your website within a few months. We focus on performing diligent keyword research, competitive analysis, onsite optimization and link building to get you to page 1. We don't stop till we get you to the top. The more people we drive to your website thSuggest edits
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The crew of JDS Azumaya must stop a rogue JMSDF vessel from inciting a war with America.
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Mar 14, Web services are client and server applications that communicate over the World Wide Web's (WWW) HyperText. Transfer Protocol (HTTP). Title RESTful PHP Web Services; Author(s) Samisa Abeysinghe; Publisher: Packt Publishing (October 30, ); Paperback pages; eBook PDF, MB. May 1, The Resource-Oriented Architecture Versus Big Web Services. .. ents written in Ruby, Python, Java, C#, and PHP. We also give.
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Apr 19, Media, Inc. PHP Web Services, the image of an Alpine Accentor, and related trade . For example: "PHP Web Services by Lorna Jane Mitchell. The Need for RESTful Web Services. REST Tools and Frameworks in PHP. XML Parsers. Tools for Accessing Services. Providing Services. Concept coined by Roy Fielding. ▫ Uses the web or to be precise HTTP or HTTPS exclusive for transmitting web service request and response. ▫ Classic setup.
Go to Subscription. This is because there are a lot of people now using mobile devices and a wider variety of applications moving to the cloud. The below method will be used to fulfill the below-mentioned scenario If a user wants a list of all Tutorials available, then the below code would need to be written to accomplish this. Run the Filddler tool and perform the below steps; Go to the composer section. Graphics Programming.
When all major platforms could access the Web using Web browsers, different platforms couldn't interact. For these platforms to work together, Web-applications were developed. Web-applications are simply applications that run on the web. These are built around the Web browser standards and can be used by any browser on any platform.
By using Web services, your application can publish its function or message to the rest of the world. Web services can offer application-components like: Web services can help to solve the interoperability problem by giving different applications a way to link their data.
With Web services you can exchange data between different applications and different platforms.
In the following example we will use ASP. This document is saved as an.
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Frequently bought together. Learn more Add to cart. So if the link to our web service is http: This section of code is used to go through our list of strings in the 'lst' variable and return all of them to the calling program.
The web service would then need to return the Tutorial name which had the Tutorial id 1. This section of code is used to return the "Tutorial name" which has the Tutorial id passed to the web method. By default, what needs to be remembered is that whatever is passed to the URL in the browser is a string.
But you have to remember that the Index to our list has to be an integer, so we are adding the necessary code to first convert the Tutorialid to an Integer and then use it to access the index position in our list and Then return the value to the calling program accordingly. This method will be invoked whenever we want to add a string value to our list of Tutorials via the POST method.
Code Explanation: This allows the method to be invoked via the POST call. The second line of code is used to add the string value passed via the POST call to our existing list of Tutorial strings. TryParse Tutorialid, out pid ; 1st.
The Int32 function in code is used to convert the Tutorial ID from a string variable to an integer. Running your first Restful web service Now that we have created our entire web service in the above section.
Let's see how we can run the Tutorial service so that it can be invoked from any client. To run the web service, please follow the below steps Step 1 Right click on the Project file — Webservice.
This will ensure that this project is run when Visual Studio runs the entire solution Step 3 The next step is to run the project itself. Now depending on the default browser installed on the system, the appropriate browser name will come next to the run button in Visual Studio. In our case, we have Google Chrome showing up.
Just click on this button. In the above output, You can see that the browser is invoking the 'GET' verb and executing the 'GetAllTutorial' method in the web service.
This module is used to display all the Tutorials exposed by our web service. Testing your first Restful web service In the above section, we have already seen how to use the browser to execute the 'GET' verb and invoke the 'GetAllTutorial.
If you hit the enter button, you will get the below output Now you will see the output of Queues which actually corresponds to the number 1 in our list of Tutorial Strings. It also shows that the value of 1 is being passed successfully via the browser to our web service and to our method and that is why we are getting the correct corresponding value of "Queues" in the browser.
Next let's consume our web service by executing the below scenario. For this, you need to install the tool called "Fiddler" which is a free downloadable tool from the site.
Run the Filddler tool and perform the below steps; Go to the composer section. This is used to create requests which can be submitted to any web application.
Remember that our POST request method in our Web service only accepts json style data so we need to ensure this is specified when we are sending a request to our application. Finally, we need to enter our data. Remember that our method for POST accepts a parameter called 'str.
Finally, just click the Execute button in fiddler. Now, when we browse to the Tutorial URL to show all the strings in our Tutorial list, you will now see the value of "Trees" is also present. This shows that the POST request to the web service was successfully executed and that it was successfully added to our Tutorial List. Run the Filddler tool and perform the below steps Go to the composer section. Ensure that the id which is used to delete a string in the list sent via the URL as a parameter.
In our example, we are sending 1 so this will delete the 2 nd element in our collection which is "Queues". Now, when we browse to the Tutorial URL to show all the strings in our Tutorial list, you will notice that the value of "Queues" is no longer present. The element at index no 1 in our list of Tutorial strings was successfully deleted.
REST is used to build web services that are lightweight, maintainable, and scalable in nature.
More and more applications are moving to the Restful architecture. This is because there are a lot of people now using mobile devices and a wider variety of applications moving to the cloud.
Visual Studio and. Net can be used to create Restful web services. What is WSDL? What is WS Security? WS Security is a standard that addresses security when data is exchanged as part of A web service is a kind of software that is accessible on the Internet. It makes SAP Tutorials. Net C CodeIgniter. Blockchain Go Programming Reviews. Tableau Talend ZooKeeper. Artificial Intelligence Keras.
R Programming TensorFlow. Data Science PyTorch. Web service. What are Microservices?


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Thanks for your interest in Amazon Uk Fba Address!
I'm currently working on a detailed video to get you the latest information on this…
But in the meantime…
Checkout the best ClickFunnels offers, benefits, and features below.
In this day and also age, the way your business operates online could make or damage you.
Just how do most services currently have an existence online?
The truth of the issue is, nonetheless, that websites have considerably evolved over the previous years – as well as the approaches of old are not sensible for contemporary organisation.
Back then, it would be adequate to have a basic website with a web page, services, rates, about us, and get in touch with web pages.
A potential client would certainly go to your website, scroll about, go to the different pages and also take in material as they please.
Nonetheless, if you are a service investing any type of money on marketing, you want to manage what clients are learning more about on your website, present deals at the correct time, as well as take full advantage of the earnings you make from each individual.
How does one attain this?
Making use of sales funnels.
Get in ClickFunnels
ClickFunnels is the simplest means to earn high converting sales as well as marketing funnels.
It is an unique tool created especially to transform prospective clients right into customers.
It truly is an all-in-one option to create sales funnels as well as consists of touchdown web pages, e-mail integration, billing, webinars, subscription websites, therefore much more. It's not surprising that it has swiftly become a preferred tool for marketers.
Below is my comprehensive ClickFunnels Review, including favorite attributes, pricing, pros/cons, and also contrasts against competitors.
Amazon Uk Fba Address: But First, Just What Is a Sales Funnel?
Sales funnels (also called advertising and marketing funnels) are multi-step campaigns that are made to move potential prospects with your sales procedure, as well as turn them right into customers.
Image a real-life funnel. On top, you put liquid in, which limits towards one fixed destination.
In sales, a similar event takes place. On top, visitors get to your site, but not all who get in make it from the other end as buyers.
Lots of things need to happen from the time a site visitor enters your channel, to the moment they act and also successfully finish an acquisition.
By damaging down the client's journey right into smaller actions, you could be much more specific concerning how and when you offer a deal to your audience.
The detailed steps in a funnel may look something like this:
- Unqualified lead gets to landing web page
- Page connects the very first offer (something cost-free to collect an email).
- As soon as e-mail is accumulated, main deal is pitched.
- Lead becomes a paying client.
- More e-mail communication supplying consumer value.
- Further partnership building
- Recurring sales.
ClickFunnels likewise has a graphic that discusses this in a straightforward way:.
What is ClickFunnels?
As discussed previously, ClickFunnels is the most effective sales channel software around today.
The company makes the strong claim of offering you every little thing you need to market, sell, and also supply your items online – as well as they definitely provide.
A standard channel will use an opt-in web page (to collect e-mail addresses), an email automobile -responder (to send emails to your consumers), plus an added sales page with some content and also an order kind, possibly adhered to by additional content, a subscription site, etc
. Previously, you would certainly have to make use of various platforms and also tools to accomplish all these tasks such as:
- Produce an internet site
- Find Hosting
- Locate an autoresponder service
- Locate subscription website software application
- Locate split-testing software application … and so on
Yet ClickFunnels cares for whatever with their platform. You not just save a ton of money by not having to acquire various products/services, yet you likewise stay clear of the technological mess of having to establish whatever up, as well as can focus on just what's really essential – growing your business.
ClickFunnels uses a Complimentary 14-Day Trial, so you get to check out the tool and really see if it's right for your company.
Favorite Functions
* Rapidly Develop Pages Making Use Of Themes and also Components *.
Before getting also much, it is very important to understand that a funnel is a collection of web pages put together in a strategic order, with the goal of converting as numerous leads into clients. As well as a web page is simply a collection of different elements designed to get someone to take a particular activity.
ClickFunnels supplies even more compared to 50 different components to help you construct the best page. The editor is incredibly very easy to make use of as well as all you have to do is drag and also drop different components on the page, as well as update the message and look to fit your demands – no coding abilities needed!
ClickFunnels also makes your life much easier by giving you with a lots of complimentary templates.
As a matter of fact, ClickFunnels gives over 37 types of pages for you to mix as well as match with. These are damaged down into the following 10 categories:
- Presell Pages: Survey Page, Post Page, Presell Web Page, Clickpop Web Page
- Optin Pages: Squeeze Web Page, Reverse Press Page, Lead Magnet, Discount Coupon
- Thanks Pages: Thank You Web Page, Offer Wall Surface, Bridge Web Page, Share Web Page
- Sales Pages: Video Clip Sales Web Page, Sales Letter Page, Item Launch Page
- OTO Pages: Upsell Page, Downsell Web Page
- Order Forms: 2 Action Order Page, Traditional Order Web Page, Video Clip Sales Letter Order Web Page, Sales Letter Order Page, Product Release Order Web Page
- Webinar Pages: Webinar Registration Web Page, Webinar Confirmation Web Page, Webinar Broadcast Room, Webinar Replay Room
- Membership Pages: Accessibility Web page, Participant's Area
- Associate Pages: Gain Access To Page, Associate Area
- Other Pages: Application Page, Ask Page, Shop Front, Web Page, Hero Web Page, Hangout Page, Live Trial Page
The pre-built layouts are totally personalized, as well as are what most individuals use.
You are able to pick a theme, edit or change the elements with your very own, and your brand-new web page is ready to go.
You can also connect any funnel you develop with your very own e-mail advertising and marketing solution (if you don't utilize the one consisted of in ClickFunnels), and also utilize the ClickFunnels built in payment system.
This is likewise a great time to mention that ClickFunnels gives very useful and understandable training videos when you initially register. I very suggest experiencing those since they rapidly enable you to utilize the tool at its full capability, and also you'll have more fun messing around. Amazon Uk Fba Address
* Develop One-Click Subscription Websites *.
One of the most effective features with ClickFunnels is the ability to conveniently create subscription sites and provide material to your target market in one location.
Your subscription site will come complete with enrollment pages, membership access web pages, and also web content pages which you can conveniently lock or leak feed to your consumers according to acquisitions they made in your channel.
ClickFunnels membership sites permit you to send emails, easily manage your e-mails, as well as develop an area all while getting rid of the stress that's related to other options such as Kajabi, or WordPress systems.
It's really helpful to not have to get a different software program or plugin to produce membership sites.
* Email Integration & Actionetics *.
With every funnel comes e-mail listing structure opportunities.
ClickFunnels sustains e-mail integration with all the significant email automation platforms such as:
- Active Campaign
- Aweber
- Constant Contact
- ConvertKit
- Drip
- Get Response
- Hubspot
- InfusionSoft
- Mad Mimi
- MailChimp
- Market Hero
- Ontraport
- Salesforce
- Sendlane
- And others
However, ClickFunnels likewise has their very own effective automation tool called Actionetics.
Although you could develop, schedule, and also deliver emails as with any other email advertising and marketing platform, Actionetics is so much extra.
I enjoy Actionetics since it not only replaces your email marketing yet carrier advertising as well as SMS marketing software programs also. This takes automation to an entire new level as well as helps you connect the perfect message to your customers, exactly when they need it. A video clip introduction of Actionetics will certainly be provided additionally listed below.
* Invoicing as well as Repayment Combination *.
A remarkable feature within ClickFunnels is the capacity to accumulate all the billing information from your customers right on your sales web page. Selling is made a lot easier when customers do not need to leave your website.
ClickFunnels integrates with significant settlement gateways such as PayPal, Red Stripe, as well as InfusionSoft, to name a few.
ClickFunnels Prices.
While you could begin with the Free 14-Day Trial, there are three various pricing alternatives with ClickFunnels:
- $ 97/month.
- $ 297/month.
- $ 997 mass discount plan (suggested).
I'll go into detail for each and every of these plans listed below.
1. ClickFunnels Requirement Strategy – $97/month.
The conventional plan consists of every one of the attributes you would certainly need within ClickFunnels, yet with constraints on the number of funnels (20) and also pages (100) you can have in your account, in addition to how many visitors (20K) could view your web pages monthly.
You likewise do not receive advanced functionality such as ClickFunnels very own email advertising and marketing and also affiliate tracking devices.
2. ClickFunnels Etison Suite – $297/month.
This strategy includes all the bells and also whistles of the conventional plan, with no constraints. It likewise has 2 added items produced by ClickFunnels called Actionetics (e-mail advertising and marketing) and Knapsack (associate administration platform).
In Actionetics – you can take care of every one of your get in touches with that subscribe to your list, send out e-mail broadcasts, as well as develop a host of other automations. Amazon Uk Fba Address
The distinction between both strategies really is the constraints, and Actionetics/Backpack. If you are a standard customer as well as do not expect to utilize greater than 20 funnels in your account – the Standard Plan ought to be adequate.
Nevertheless, if you plan to have an associate program or want to maintain your e-mail advertising and marketing within ClickFunnels and not utilize a 3rd party software application, the Etison Collection is for you.
You can always begin on the reduced plan and also upgrade if needed.
3. Funnel Hacks System – $997
For anybody that's serious concerning their organisation, the ClickFunnels Funnel Hacks System is the bargain of the century.
The $997 Funnel Hacks System includes robust training programs packed with 6-month accessibility to the ClickFunnels Etison Collection.
This is an extraordinary deal since outside of this program, 6-months of Etison Collection alone would cost you $1782.
Not only are you conserving $785 but you're obtaining a lots of trainings as well as guides to assist you get one of the most out of ClickFunnels!
ClickFunnels Advantages And Disadvantages
- Producing funnels is really simple, simple, as well as fast
- All-in-one system with whatever your business should win
- Split screening and conversion tracking included
- Email combination with all of the major e-mail autoresponder platforms
- Payment processing capabilities within ClickFunnels
- ClickFunnels is always adapting as well as updating to the moments
- There is constantly support available (whether online or otherwise).
- Exceptionally energetic Facebook Team Community.
- Free 14-Day Trial – permits you to try it take the chance of free.
- As incredible as ClickFunnels is, it certainly is not an affordable service as well as needs a continual registration to make use of
- Assistance isn't really always the fastest and may extract from 1 minute to 24-HOUR depending upon the problem.
ClickFunnels vs. Every person Else.
Many individuals ask just how ClickFunnels compares with various other landing web page home builders such as Leadpages, Unbounce, as well as Infusionsoft.
Generally it's not really a reasonable comparison because each of these devices stands out is one location or the various other.
The graph above gives a thorough analysis – but I'll highlight some of the significant comparisons below.
ClickFunnels vs Leadpages
Before ClickFunnels, Leadpages was the large pet.
Leadpages is just a lead capture software program – absolutely nothing more. You can produce touchdown pages, lead boxes, collect leads … that's pretty much it. Furthermore, the Leadpages themes are additionally restricted on modification.
ClickFunnels is even more versatile – it's a lot easier to use and also does so much more than produce lead capture web pages.
Basically, Leadpages is truly just a landing web page building contractor, while ClickFunnels is concentrated around building extremely integrated funnels.
ClickFunnels vs Infusionsoft
Infusionsoft is not a touchdown page or sales web page contractor. It has several of that functionality developed it, however that's not just what it's known for.
At it's core, Infusionsoft is a CRM platform – one that enables you to manage your entire client data source. ClickFunnels has this ability with Actionetics, yet it's not almost as advanced as Infusionsoft.
Infusionsoft is additionally exceptionally pricey and also forces every new client to pay $2000 for a necessary kickstart mentoring bundle simply to learn how to make use of the complex system (which is infamously challenging to use).
ClickFunnels Affiliate Program
There are two major courses individuals go down as ClickFunnels customers.
Those that opt to use the device for their service – in hopes of eventually accomplish the Two Comma Club (over $1M in revenue).
And those that are interested in earning easy revenue as a ClickFunnels Associate and also winning the Desire Cars and truck Competition (where they pay $500/$1000 towards your desire car if you reach 100/200 active regular monthly signups, specifically).
With a monstrous 40% regular monthly repeating payment, ClickFunnels easily has among the greatest associate programs of any kind of system out there.
That's right – you get paid an ongoing 40% commission on every affiliate signup you make with the ClickFunnels Affiliate Program. Yet, just what does that actually correspond to?
The standard strategy is a $97/month financial investment and also the Etison Suite plan is a $297/month investment. for that reason you make $38.80 per fundamental strategy and also $118.80 each Etison Suite plan … every single month!
Usually, every 100 signups will certainly bring in $4000/month in affiliate compensations (essentially depending on how many Etison Plan individuals are in there).
Visit this site for more information concerning becoming a ClickFunnels Affiliate.
All-time Low Line
ClickFunnels is hands down the best platform if you are wanting to easily build high converting sales funnels.
Because it was developed from scratch to be the most effective sales funnel home builder, it defeats all the competition in that respect.
Externally, it might not be the most affordable product out there – yet if you use it to its complete ability, your service will certainly become a lot more lucrative as well as you will conserve money from not having to make use of other devices. Amazon Uk Fba Address
If you have actually read this far right into my ClickFunnels Review, I recommend you see on your own with a Free 14-Day Trial below.


text:
PR Newswire
Global Construction Additives Market Set for Robust CAGR of 6.6% from 2018 to 2025
Adopting environmentally sustainable and regulatory-compliant additive solutions will augment growth opportunities, finds Frost & Sullivan
LONDON, Aug. 13, 2019 /PRNewswire/ — Growth opportunities in the global construction additives market look promising over the next six years. A global uptick in construction activities, stringent building codes and environmental standards, and increasing usage of concrete admixtures are key factors driving the global construction additives market revenues towards $16.97 billion by 2025. This is also creating high demand for products such as superplasticisers and iron-oxide pigments. Frost & Sullivan expects the market to expand at a robust CAGR of 6.6% from 2018–2025.
"With a constantly evolving regulatory landscape, manufacturers should look towards adopting more environmentally sustainable and regulatory-compliant additive solutions and manufacturing processes," said Prathmesh Limaye, Senior Analyst, Chemicals & Materials in Infrastructure & Mobility. "This will enable participants to attract customers that are focused on high durability and environmental sustainability as well as harness lucrative revenues in the more mature markets of Western Europe, North America, and China."
For further information on this analysis, please visit http://frost.ly/3oq
From a regional perspective, Asia-Pacific is expected to be the biggest market for construction additives and the fastest growing sector due to industrialisation, urbanisation, and high economic growth. These factors are also expected to boost growth in Latin America. Europe will witness robust demand for construction additives due to new construction activities within Eastern Europe and remodelled construction in Western Europe. Furthermore, the Summer Olympics in Paris in 2024 are expected to expand France's infrastructure prospects.
"North America will witness the slowest growth among the regions, as the construction activity is still affected by the 2008 recession; however, it is slowly picking up," noted Limaye. "The Middle East is anticipated to witness strong growth with the Dubai World Expo in 2020 and Qatar FIFA World Cup in 2022 acting as key enablers."
Limaye recommends participants look towards the development and supply of products that can be manufactured with locally sourced raw materials to enable the supply of price-competitive products. This will avoid dependency on traditional manufacturing practices, which have the potential to be restricted in the future by regulatory authorities. They should also aim to strengthen relationships with major applicators and distribution networks by offering training and collaborative product development.
Additional growth opportunities participants should aim to secure include:
- Improving their portfolios with products that can be customised to end-user specifications, such as application and ease of installation.
- Expanding operations with high-growth prospects to Asia-Pacific due to the region's growing infrastructure and construction development.
- Offering products that are comparative with those offered by regional and local manufacturers in developing countries.
Frost & Sullivan's recent analysis, Global Construction Additives Market, Forecast to 2025, explores the factors and trends that have shaped the global rare earth materials landscape, the challenges that lie ahead, and the opportunities that can be tapped. The research provides a detailed analysis of the growth opportunities for key players in the rare earth materials space.
Global Construction Additives Market, Forecast to 2025 is part of Frost & Sullivan's Chemicals & Materials in Infrastructure and Mobility research and analyses available through the Frost & Sullivan Leadership Council, which helps organisations identify a continuous flow of growth opportunities to succeed in an unpredictable future.
About Frost & Sullivan
For over five decades, Frost & Sullivan has become world-renowned for its role in helping investors, corporate leaders and governments navigate economic changes and identify disruptive technologies, Mega Trends, new business models and companies to action, resulting in a continuous flow of growth opportunities to drive future success. Contact us: Start the discussion.
Global Construction Additives Market, Forecast to 2025
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Find something curious…
Notice is given that on 5 November 2019 Livingstone Shire Council resolved to adopt Infrastructure Charges Resolution
(No. 4) Livingstone Shire 2019 which will have effect on and from 11 November 2019.
The principal changes proposed include:
1. Removing all Desired Standards of Service. These are now included in the Local Government Infrastructure Plan within
the Livingstone Planning Scheme 2018;
2. Removing all Schedule of Works. These are now included in the Local Government Infrastructure Plan within the
Livingstone Planning Scheme 2018;
3. Removing all Plans for Future Trunk Infrastructure. These are now included in the Local Government Infrastructure Plan
within the Livingstone Planning Scheme 2018;
4. Retaining the Priority Infrastructure Area map links that show charge areas 1, 2 and 3. It is noted that the Local
Government Infrastructure Plan mapping of the Priority Infrastructure Area does not show the charge areas;
5. Updating the relevant references to acknowledge Part 4 of the Planning Scheme – which is the Local Government
Infrastructure Plan;
6. Reducing all unnecessary references to the Priority Infrastructure Area;
7. Changing references to legislation from the Sustainable Planning Act 2009 to the Planning Act 2016;
8. Ensuring that calculations within the document reflect the correct calculation of apportionments. There are no changes
to apportionments;
9. Amendments to charges levied in relation to short term accommodation (Farm Stay) and Home Based Business (Bed
and Breakfast);
10. Amendments to charges levied in relation to aligning the previous charge for annexed apartments. The new reference
to secondary dwellings under the Queensland Planning Provisions defined terms is resulting in secondary dwellings that
are similar in size to a stand-alone house and are not small in scale. Where secondary dwellings exceed the 80m²
excessively and are clearly a separate house and are not commensurate with a granny flat or annexed apartment, these
will attract an infrastructure charge to reflect the similarity to a dual occupancy. The new charge is however less than the
previous charge for an annexed apartment; and
11. Refining examples and references to offsets, conversions, refunds and credits
The following key features of the Adopted Infrastructure Charges Resolution remain unchanged:
a.the Priority Infrastructure Area;
b.the charge areas; and
c.the ability to apply indexing to the charges with automatic increase provisions.
The amendments do not address the timing of the payment of infrastructure charges. The trigger for payment of levied
charges are regulated in sections 122 and 123 of the Planning Act 2016.
Incentive policies and details about deferment are a separate decision of Council and if made will be made available on
councils website.
The new resolution maintains charges well below the maximum allowable charges.
The new resolution will take effect for new applications lodged after 11 November 2019.
A copy of the Adopted Infrastructure Charges Resolution (No. 4) Livingstone Shire 2019 is available for inspection and
purchase at Livingstone Shire Council's Customer Service Centre's. The resolution is also available on Council's website at
Chris Murdoch, Chief Executive Officer Livingstone Shire Council
Rockhampton 4700


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text:
'Ramos could play up front' - Real Madrid 'warrior' saluted by Solari
Santiago Solari has admitted that Sergio Ramos could be used as a striker, with a Real Madrid "warrior" having proved his goalscoring pedigree once again.
The World Cup winner has been a regular source of firepower for the Blancos down the years.
Watch Champions League | Soccer Live Streaming | DAZN CA
In 594 appearances for Real, Ramos has recorded 82 goals – many of them vital, such as priceless efforts in Champions League finals.
His most recent outing saw him net an important brace, with a late surge staged against Girona in the first leg of a Copa del Rey quarter-final to secure a 4-2 win.
Ramos converted a Panenka penalty shortly before half-time, before restoring Real's lead on the night 13 minutes from the end.
That contribution in the final third has not gone unnoticed, with Solari conceding that he may be tempted to use the 32-year-old as a frontman if the situation ever called for such a move.
He told reporters: "I wouldn't rule it out.
"Sergio is a warrior, a leader. He showed that in defence, and in the opposition area heading his second goal just like a centre-forward.
"He took the penalty like that [a Panenka], he's a specialist - so perfect. He doesn't just take them like that, but in many different ways."
Ramos has become famed for his penalty-taking expertise since inheriting spot-kick duty in the wake of Cristiano Ronaldo's departure from the Santiago Bernabeu.
He had already displayed plenty of composure from 12 yards prior to that, but has been a reliable option for Real this season.
There is, however, an acceptance on his part that he cannot continue to delicately chip every penalty he takes down the middle, with opposition goalkeepers now wise to his preferred approach.
Ramos told Real's official website of the decisions he now faces: "It's how I like to play and hopefully they will keep going in, but I can't take it for granted.
"Keepers are staying on their feet for longer, so maybe I'll have to put it to the side next time."
The Blancos will be back in La Liga action on Sunday when they travel to Espanyol, with Solari's side currently sat 10 points adrift of another Catalan foe – arch-rivals Barcelona – in the Spanish top-flight table.