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Iron availability regulates ferritin synthesis posttranscriptionally by the interaction between iron-regulatory proteins (IRPs) and an iron responsive element (IRE), a stem-loop sequence located on the 5′ untranslated region of ferritin mRNA. IRPs recognize IREs as a sequence/structure motif, blocking ferritin translation. Recently, we and others independently described families with a combination of hyperferritinemia (serum L-ferritin ≥ 1,000 μg/L, without iron overload) and congenital bilateral cataract, transmitted as an autosomal-dominant trait. The molecular basis were two distinct point mutations in the highly conserved CAGUG(X) hexaloop of L-ferritin IRE on chromosome 19. A new three-generation family with a similar phenotype and a unique genotype is here reported. DNA amplification by polymerase chain reaction and sequence analysis showed a 29-base pair deletion in the L-ferritin IRE, involving the whole 5′ sequence essential to the base pairing of the IRE stem. This deletion is predicted to cause the disruption of IRE stem-loop secondary structure and the nearly complete abolition of the negative control of ferritin synthesis by IRE/IRP binding. Hereditary Hyperferritinemia-Cataract Syndrome (HHCS) appears as a new genetic disorder with a unique phenotype associated with at least four different mutations in the L-ferritin IRE. Hematologists should take into account HHCS in the differential diagnosis of unexplained hyperferritinemia.
IN THE LAST decade important advances have been made in understanding of the regulation of the synthesis of ferritin, the ubiquitous iron-storing protein.1 Whereas cytokines (ie, interleukin-1α and tumor necrosis factor-α) can activate ferritin gene transcription as well as translation, explaining the hyperferritinemia commonly found in cancer and inflammatory diseases,2,3 in absence of these conditions ferritin synthesis is finely regulated at the translational level by iron availability. This mechanism is part of a coordinated control of the expression of other proteins involved in iron homeostasis, such as erythroid δ-aminolevulinate synthase (δ-ALAs) and the transferrin receptor (TfR) (see Fig 1 and reference 4 for a review). It is achieved by the high-affinity interaction between iron-regulatory proteins (IRP 1 and 2) and iron responsive elements (IREs), which are a family of stem-loop sequences located in the untranslated regions (UTR) of the mRNAs.5 A single IRE is located in the 5′ UTR of ferritin and δ-ALAs mRNAs, where binding of IRPs represses translation; on the other hand, five IREs are in the 3′ UTR of the TfR, where binding of IRPs stabilizes the mRNA. Intracellular iron levels modulate the affinity of the IRPs for the IREs. When iron is low, the IRPs/IREs binding prevents iron utilization and storage by blocking the translation of ferritin and δ-ALAs mRNAs, whereas iron uptake is promoted by increasing the synthesis of TfR. Conversely, in iron-repleted cells the affinity of IRPs for IREs is low, so that the synthesis of ferritin and δ-ALAs increases, whereas that of TfR decreases.
Ferritin is a multimeric hollow sphere composed of 24 heavy (H, Mr 21,000) and light (L, Mr 19,000) subunits, the genes of which have been assigned to human chromosome 11 and 19, respectively.6 Circulating ferritin, a by-product of intracellular ferritin synthesis,7 generally reflects the size of iron stores, providing a reliable biochemical marker of body iron status. Hereditary hemochromatosis (HH), an autosomal recessive disorder due to a gene close to HLA on chromosome 68 and characterized by parenchymal iron overload, has long been considered the only genetic disease with elevated serum ferritin. Biochemical features of HH are usually an early increase of transferrin saturation followed by a progressive rise of the serum ferritin level, which reflects the increasing iron stores due to excessive iron absorption during several decades.9
In 1995 we first described two Italian families with a new autosomal-dominant genetic disorder, the "Hereditary Hyperferritinemia-Cataract Syndrome" (HHCS),10 clinically characterized by the combination of congenital bilateral cataract and marked elevation of serum ferritin levels (≥1,000 μg/L). The hyperferritinemia was found to be not related to iron overload and entirely due to the increase of the L-subunit, as determined by subunit specific immunoassay. The HHCS is clearly distinguishable from HH because of: (1) the dominant transmission; (2) the lack of any relation with HLA; (3) normal to low serum iron and transferrin saturation, without evidence of parenchymal iron overload assessed by liver and bone marrow biopsy. Typically, if unnecessary phlebotomies are performed, HHCS patients rapidly develop iron-deficient anemia (reversed by adequate iron therapy), despite persistently elevated levels of serum ferritin.10
A few months after the description of HHCS, we identified in the first family the molecular basis of the new disease, consisting of a point mutation in the IRE of ferritin L-subunit gene on chromosome 19 (in the region 19q13.3 → 19qter).11 It was a single base substitution (G to C) in the third nucleotide of the highly conserved CAGUG motif of the IRE loop, essential to the high-affinity interaction between ferritin mRNA and the IRP. Beaumont et al12 also described another three-generation French family with clinical characteristics identical to those of our HHCS patients and carrying an analogue mutation in the L-ferritin IRE, ie, an A to G change in the second nucleotide of the CAGUG loop.12 A third distinct point mutation (G to A change in the IRE bulge) was then found in the second Italian family of our original report.13
We report here a new Italian family with HHCS caused by a 29 base pair (bp) deletion in the 5′ stem of the IRE in the ferritin L-subunit gene, the first described so far, bring to four the number of IRE mutations/deletions observed in HHCS.
Family history.This three-generation family (Fig 2), living in northern Italy for many generations, was well known to ophthalmologists for the segregation of dominantly inherited congenital bilateral cataract. Visual symptoms became clinically evident during infancy, consisting of glare and slowly progressive loss in visual acuity.
A few years ago, the proband (III-2 Fig 2), a 36-year-old female, underwent a biochemical evaluation of iron status because of slight anemia several months after her first pregnancy. Serum ferritin was 1,753 μg/L whereas serum iron and transferrin saturation were normal (92 μg/mL and 23%, respectively). To evaluate the possible occurrence of HHCS, a family study of biochemical iron parameters was performed. All family members with bilateral cataract also had marked elevation of serum ferritin (>1,000 μg/mL), with no other hematological or biochemical abnormalities, including normal to low serum iron and transferrin saturation. Following inquiry by the proband at the Service of Medical Genetics of the local Hospital, she was directed to our Institute based on a search of a genetic database on the Internet,14 that reported information about our previous description of the HHCS. The age of surgery for cataract and serum L-ferritin levels are shown in Fig 2. A complete family history did not reveal any other clinical symptoms that are apparently linked to the new syndrome.
Molecular analysis of the 5′ UTR of the L-ferritin gene.Genomic DNA was isolated from peripheral blood lymphocytes according to standard protocols. Polymerase chain reaction (PCR) amplification was performed on 300 ng of genomic DNA. Denaturation was at 94°C, annealing at 57°C, and extension at 72°C, each step for 30 seconds for a total number of 30 cycles. The PCR mixture contained in a final volume of 50 μL: 10 mmol/L Tris-HCl (pH 8.4), 50 mmol/L KCl, 2.5 mmol/L MgCl, 0.01% gelatin, 0.01% Tween 20, 0.01% NP40, 2 U of Taq polymerase, 1% dimethyl sulfoxide (DMSO), 200 mmol/L of each dNTP, 10 pmol of each primer. The primers were: T7F1-TCCTTGCCACCGCAGATTG, to which the T7 tail (TAATACGACTCACTATAGGG) was added; and R1-CCGGATCTGTTCGTCAAAC. Amplified fragments were then sequenced on an automatic sequencer (Applied Biosystem 373A, Foster City, CA), according to manufacturer's protocols.
Sequence analysis of the 5′ UTR of the L-ferritin gene permitted the identification of a 29-bp deletion (Fig 3a). The deletion involved residues 10-38 of the normal L-ferritin transcript, corresponding to the 5′ stem of the IRE stem-loop (Fig 3b). The mutation could be easily analyzed by PCR followed by agarose gel electrophoresis counterstained by ethidium bromide. It was found to segregate with the disease within the affected members of the family studied (Fig 4).
Clinical and molecular data from this family, carrying a unique deletion in the L-ferritin IRE, give a substantial support to the recent description of the HHCS previously made by us10,11 and, independently, by Beaumont et al.12 In particular, new information about the molecular heterogeneity of the disease is added, as three different single-base substitution in the L-ferritin IRE were so far reported in HHCS families. The IRE(s) are a family of cis-acting stem-loop structures of approximately 30 nucleotides located in mRNAs that encode proteins involved in iron homeostasis.5 Both primary and secondary structures of the IREs are highly conserved during evolution; a hairpin with terminal CAGUG(X) hexaloop is common to all known IREs. This probably reflects the central importance to life of regulating iron metabolism. Depending on the location in the mRNA (5′- or 3′-UTRs) and the specific structure, IREs control either mRNA translation or stabilization. Ferritin mRNA has a single IRE located near the cap of the 5′ UTR. Besides the hairpin structure, distinct features of the ferritin IRE are a G/C-rich stem and an internal UGC bulge, which interrupts the upper stem on the 5′ side (see Fig 3b).5 A series of site-directed mutagenesis experiments have clearly shown that both the sequence and the secondary structure of the IRE stem-loop are essential to the maintenance of the iron-dependent regulation of protein translation.4,15-17 For example, single substitution of nucleotides in the loop or mutations leading to disruption of base pairing in the upper stem decreased the IRE/IRP affinity and/or the capability of regulating translation in response to iron. In keeping with these data, the different single base substitutions in the IRE hexaloop previously found in Italian and French families were shown to be the molecular basis of the HHCS. An in vitro study testing the point mutation in the IRE loop detected by us in the first HHCS family showed that this IRE had a 28-fold lower affinity for IRP than did the native RNA.17 Similarly, the mutation detected in French HHCS patients abolished the binding of IRP to IRE in vitro, and cultured lymphoblastoid cells from the probands exhibited high constitutive, poorly regulated L-ferritin synthesis.12 These data were consistent with the biochemical hallmark of the HHCS, ie, hyperferritinemia as expression of iron-insensitive upregulation of L-ferritin synthesis due to loss of the inhibition of ferritin mRNA translation physiologically operated by the IRE/IRP interaction.
As expected, site-directed mutagenesis studies also showed that even minimal (single base) deletions in the IRE hexaloop reduced IRE/IRP binding more drastically (up to 650-fold) than did substitutions.17 Moreover, the bulge C on the 5′ upper side of the stem was also shown to be critical for the IRE/IRP interaction, as its removal determined a 378-fold reduction of binding affinity with respect to the native IRE.17 In the family here reported, the molecular basis of the iron insensitive upregulation of ferritin expression was represented by a relatively large deletion spanning 29 nucleotides on the L-ferritin IRE. Deleted nucleotides corresponded to the whole 5′ sequence involved in the base pairing essential to form the IRE stem, including the C bulge in the upper stem (Fig 3b). Thus, this deletion is predicted to disrupt the IRE stem-loop secondary structure, leading to the nearly complete abolition of the negative control of ferritin synthesis by IRE/IRP binding.
Despite this unique, apparently severe genotype, the phenotype in this new family is relatively attenuated and quite similar to that previously reported in HHCS families.10,12 The increase of serum L-ferritin was of the same magnitude, serum transferrin saturation tended to be normal to low, and early-onset cataract was the only constantly associated symptom. The lens opacities showed a relatively slow progression during decades from dust-like deposits to starring opacities, so that surgical correction could be delayed to the fourth decade or later.
The mechanism of cataract formation in HHCS remains obscure. The heterogeneity of molecular defects in the L-ferritin IRE leading to the same phenotype, further strengthened by this report, suggests that cataract formation is likely a direct consequence of cellular L-ferritin overproduction. Noteworthy, lens epithelial cells are prone to active ferritin synthesis, especially in response to oxidants.18 An intracellular accumulation of L-rich apoferritin in the lens, analogous to that shown in erythrocytes10 as well as in hepatocytes from HHCS patients,12 may alter the delicate equilibrium between water-soluble proteins in the lens, ultimately leading to loss of transparency. Further studies are needed to clarify this point.
The description of this new family suggests that HHCS, which has an intrinsic interest as an unique human model providing insights into the in vivo regulation of iron homeostasis, may be not so sporadic. Hyperferritinemia is not an uncommon finding in practice. A recent survey from Lee et al19 reported that 122 of 1,826 (6.7%) ferritin determinations in a general hospital population exceeded 1,000 μg/L.19 Differential diagnosis in these circumstances included a broad range of clinical syndromes, such us HH, liver disease, malignancies, systemic infections or inflammations, transfusional iron overload and others. However, in 8 of 95 (8.4%) patients none of the above mentioned conditions could be detected. Hematologists should now consider HHCS in the differential diagnosis of "unexplained" hyperferritinemia. A mistaken diagnosis of HH could lead to unnecessary liver biopsy and/or to the rapid development of phlebotomy-induced iron-deficient anemia.10,11 Similarly, cataract is one of the commonest ocular pathology,20 and serum ferritin measurement should be considered when facing patients with a family history of early-onset cataract. In this way, additional descriptions of HHCS are expected to come, improving the description of the clinical pattern and further elucidating the pathophysiology of the new syndrome.
Supported by Telethon-Italy (Grant no. E.547).
Address reprint requests to Domenico Girelli, MD, PhD, Institute of Medical Pathology, Chair of Internal Medicine, Policlinico Borgo Roma, 37134 Verona, Italy.


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Price was right for what I wanted and ordered. Severely disappointed in quality of material as well as the print. The material is very rough. The print on my towel was much lighter than advertised and the pixels on the print were terrible and splotched with the white of the towel. I can only imagine how it would just deteriorate after a couple washes. This was supposed to be a gift and I'm embarrassed to give this as a gift.
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If you're looking to make the leap from cannabis consumer to pot producer, Home Grown Academy in Carver can help. Owners Jason Cullinan and Paul Brennan offer classes for all levels, from the aspiring cultivator to the experienced producer. Learn the fundamentals in Intro to Growing Cannabis or discover how to tackle a bigger project with Grow Room Design & Construction. The four-hour classes cost $150; a series of five goes for $500.
With the shift in federal policy, some investors are skirting the cannabis industry by either choosing to wait out the storm or by leaving it altogether for fear of increased marijuana prosecutions. However, members of Congress – both Democrats and Republicans – are pushing back with the claim that the turnover not only violates states' rights but it is also destructive and backward.


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North Korean and US officials have both said the first talks since February could take place sometime next week. Soon after the announcement, South Korea's military said North Korea launched "unidentified projectiles."
North Korea and the United States announced Tuesday that they will hold working-level nuclear talks sometime next week, which would be the first such dialogue between Washington and Pyongyang since a bilateral summit in February ended without a deal.
North Korea's state news agency said in a statement that the two sides agreed to have "preliminary contact" on October 4, and hold negotiations the next day. US State Department spokeswoman Morgan Ortagus later confirmed the talks, but did not specify an exact time or location.
After the talks were announced Tuesday evening, the South Korean military reported that "short-range projectiles" were launched Wednesday morning from the North Korean port city Wonsan.
Japan condemns launch
A Japanese government spokesperson said one of the projectiles landed in Japanese waters off of Shimane Prefecture in the country's southwest.
Japanese Prime Minister Shinzo Abe said Japan would hold a meeting of its National Security Council over a response to the launches.
"The launch of ballistic missiles violates UN Security Council resolutions. We sternly lodge a protest over the launch and strongly condemn it," said Abe.
"We will do the utmost to protect the safety of the people and stay on high alert while coordinating with the United States and the international community," he added.
Missiles and talks
The short-range launch would be the ninth by North Korea since US President Donald Trump and North Korean leader Kim Jong Un had an impromptu meeting at the Demilitarized Zone (DMZ) dividing the two Koreas in June.
Read more: Opinion: Donald Trump strolls through Kim Jong Un's North Korean minefield
The missile tests are widely seen as a strategy by Pyongyang to show its expanded military capabilities to gain leverage ahead of any new negotiations with the US.
In September, Pyongyang said it had tested a "super-large multiple rocket launcher" system, shortly after signaling it was ready to resume talks.
Trump and Kim agreed to new nuclear negotiations at the DMZ meeting, however progress has stalled due to North Korea's anger at joint US-South Korea military drills.
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wmr/se (Reuters, AP, AFP, dpa)
North Korea's ongoing weapons program has shown why an imperfect nuclear deal is better than no deal at all. By applying "maximum pressure," the US has isolated Tehran and failed to stop Pyongyang. (13.09.2019)
More progress has been made to end the Korean conflict under US President Donald Trump than in 60 years. If Trump's unconventional approach secures peace, he deserves recognition for it, writes DW's Alexander Freund. (30.06.2019)


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So to avoid infections, all medical institutions must apply the use of the aseptic techniques in all their procedures. It will also be harder for them when the patients encounter dangerous complications that can lead to worse situations and even death.
Category: Health Condition
Blue waffle disease is a fictionalized STD that came from online rumors. It is said that it is a sexually transmitted infection that disfigures and turn the vagina blue.
Bone Marrow Cancer: Signs, Common Treatment, Survival Rate
Cancer of the bone marrow is literally cancer that affects the bone marrow of a patient. But what is exactly is the bone marrow and how does it help the human body? Bone marrow is a type of tissue that is characterized as spongy and is located in the core of a person's. These bones include the thighbones and the hipbones. Stem cells that further develop and produce into many other forms of blood cells in the human body come from the said bone marrow.
Common Symptoms of Catatonic Schizophrenia
Catatonic behavior in schizophrenia might manifest as a patient's lack of reactivity to his or her surroundings.
Spigelian Hernia: What Causes It?
When a hernia forms in the Spigelian fascia or Spigelian aponeurosis, this is known as a Spigelian hernia.
Lump in Throat: What Causes It and Should you See a Doctor?
Feeling a bump or a lump in the throat without actually having one is called the globus sensation.
What Causes Inner Thigh Pain?
Injury is the most common cause of inner thigh pain.
Itchy Anus or Anal Itching: Causes and Treatment
The persistent urge to reach out to scratch your butt is known as pruritus ani or anal itching.
Flea Bites: Ways to Treat It
Fleas are very hard to detect or visibly monitor as they are rather tiny.
Flank Pain: Common Symptoms and Causes
The first sign and symptom of kidney problems or a urinary tract infection is flank pain. But then it can also be caused by pinched nerve or muscle strain.


text:
Ovarian inflammation
Ovarian inflammation
Ovarian inflammation is a popular term that means inflammation of the ovaries or also pelvic inflammatory disease. The inflammation affects multiple organs in the pelvis, including the uterus, the endometrium, fallopian tubes, ovaries and possibly the abdominal wall or the peritoneum. Ovarian inflammation is most often caused by bacteria that cause sexually transmitted diseases. A cold or direct coldness does not cause ovarian inflammation, but they are a risk factor. The cold weakens the body, which makes it easier to undergo infection.
The ovaries are an important part of the female reproductive system. It is a pair gonad that forms the female gametes, or eggs and female sex hormones, estrogens and progestogens. The ovaries are located in the pelvis on both sides of the uterus. In their close proximity are the fallopian tubes, which approach to the ovaries during ovulation to capture the released egg. Female ovulation is the moment when a mature egg leaves the ovary and is ready for fertilization, by male gametes, sperm. A fertilized egg can then develop in the environment of the uterus in to a human being. If the egg is not fertilized, the egg disappears.
Causes of ovarian inflammation
The most common causes of ovarian inflammation are two bacteria Chlamydia trachomatis and Neisseria gonorrhea (cause of gonorrhea). These bacteria are sexually transmitted. The infection spreads upwards from the cervix in to the uterus, fallopian tubes, and ovaries and also might into the peritoneum or the abdominal wall. The risk factors of ovarian inflammation are many sexual partners and unprotected sex without condoms. As already mentioned cold supports the development of ovarian inflammation, and therefore we should avoid sitting on the cold ground or wearing short shirts in cold weather.
Symptoms of ovarian inflammation
A typical symptom of ovarian inflammation is a mild to severe spasmodic pain in the lower abdomen. Sometimes there is pain during sexual intercourse, which may be associated with bleeding, as well as pain during urination, yellowish smelly discharge or prolonged menstruation. The general symptoms are sometimes high temperature, fever, nausea and vomiting. If any suspicion or presence of these symptoms, please seek your doctor as soon as possible. It is important to start treating ovarian inflammation early and thoroughly. When delayed or inadequate treatment, there is a risk of complications, which include inflammatory adhesions, ovarian cysts, tubo-ovarian abscess or ovarian torsion or rotation. By abscess is meant a cavity filled with pus. Due to inflammatory adhesions, problems associated with blocked fallopian tubes and emptying urine or stool develop. If the fallopian tubes are blocked, there is an increased risk of ectopic pregnancy or partial or complete infertility.
Diagnosis of ovarian inflammation
Early diagnosis and immediate treatment of ovarian inflammation is very important, otherwise there is a risk of developing the already mentioned complications. The doctor performs gynecological, laboratory and possibly ultrasound examination. During gynecological examination cervical pain, pain of the lower abdomen and ovaries is detected. It is important to swap a sample from the cervix. The sample is then sent to a laboratory for determination of the inflammatory agents. The sensitivity of bacterial pathogens to antibiotics is also investigated. Furthermore enlarged lymph nodes in the groin area are investigated. Patient's blood samples are analyzed in the laboratory, which again confirms an ongoing inflammation in the body. Furthermore, urine can be examined for infections of the urinary tract and kidney and the doctor may also perform tests for other STDs, including syphilis and HIV. During ultrasound examination the doctor rather looks for complications of the ovarian inflammation.
Treatment of ovarian inflammation
The treatment of ovarian inflammation is based on the administration of antibiotics. Antibiotics are chosen so they are effective on both types of bacteria. Alternatively, the treatment is adjusted according to the detected sensitivity. It is important to always use up a full dose of the antibiotics and to continue treatment even when the symptoms disappear, otherwise the disease may return. Bed rest and enough intake of fluids is also recommended. Since ovarian inflammation in the early stages is very painful, painkillers are used. Treatment of both sexual partners is necessary to prevent transmission of the infection. In the case of inflammatory adhesions, abscesses or larger cysts surgical removal is performed. The most frequently used method is laparoscopic surgery. During laparoscopy the doctor performs a few small holes in the abdomen, through which are put tools, a light source and a camera attached to a television screen on which the doctor monitors the removal of these complications.
Prevention of ovarian inflammation
Prevention of ovarian inflammation consists mainly in reducing the likelihood of sexually transmitted infections. It is mainly the use of barrier contraception, a condom. Also a good prevention is the reduction of sexual partners, especially the random ones. It is important to emphasize that if you feel pain in your lower abdomen, you must seek your gynecologist. Please do not underestimate ovarian inflammation, as they can have serious consequences.
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text: Quality Assessment of Colonoscopic Cecal Intubation An Analysis of 6 Years of Continuous Practice at a University HospitalAslinia, Florence, M.D.; Uradomo, Lance, M.D., M.P.H.; Steele, Allison, M.S.N., C.R.N.P.; Greenwald, Bruce D., M.D.; Raufman, Jean-Pierre, M.D., F.A.C.G.American Journal of Gastroenterology: April 2006 - Volume 101 - Issue 4 - p 721–731 ORIGINAL CONTRIBUTION: ENDOSCOPY Buy Abstract Author InformationAuthors BACKGROUND Despite increased emphasis on endoscopic performance indicators, e.g., cecal intubation rates, limited data from actual clinical practice have been published. OBJECTIVES Retrospective database review to determine the rate and documentation of cecal intubation during colonoscopy at the University of Maryland Medical Center. METHODS We reviewed 5,477 consecutive colonoscopies performed by 10 faculty gastroenterologists at a University hospital over a 6-yr period (March 1, 1999 to February 28, 2005). Unadjusted cecal intubation rates were analyzed as were rates that were adjusted based on the U.S. Multi-Society Task Force on Colorectal Cancer recommendations. We analyzed trends in overall and individual cecal intubation rates, circumstances that impact these rates, and the quality of documentation of cecal intubation. RESULTS The overall adjusted cecal intubation rate for the entire 6 yr was 90.3%, and increased over the study period with the highest adjusted rate (93.7%) in the most recent year studied. There was no correlation between cecal intubation rate and patient age, gastroenterology fellow involvement, or endoscopist experience and number of procedures/year. In contrast, colon cancer screening, male gender, outpatient colonoscopy, and adequate bowel preparation predicted a higher cecal intubation rate. Written and photographic documentation of cecal intubation improved significantly after 2002. CONCLUSIONS Our analysis revealed cecal intubation and documentation rates that meet current guidelines, and identified factors that may cause substantial variance in these rates depending on the nature of the practice. The present analysis confirms that computerized databases can be used to assess individual and group cecal intubation and documentation rates on an annual basis, and to make these data available to the public. Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, Maryland Reprint requests and correspondence: Jean-Pierre Raufman, M.D., F.A.C.G., Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, 22 S. Greene Street, N3W62, Baltimore, MD 21201. Received June 30, 2005; accepted August 28, 2005. © The American College of Gastroenterology 2006. All Rights Reserved.


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Keychain AutoUnlock - Tool to automatically unlock the OS 9 Keychain
Version: 1.2Keychain AutoUnlock is a mini-utility that will automatically unlock your keychain on system startup. It will also unlock it whenever you run the application.
License: Free
Operating System: Mac OS X
Homepage: www.chaoticsoftware.com
Developed by:
It's quite handy for those of us who love the keychain, but hate the fact that every time we restart or boot-up, we must unlock it first before it can be used.
What's New in This Release:
· Keychain installed and activeAdded the deluxe "how to" instructions below in the "How Do I Use It?" section.
· Added a new feature to "always prompt" on startup. Yes, this sort of defeats the purpose of having it auto-unlock, but it is useful for certain software configurations, where the keychain screws up by trying to open certain servers before other software is setup correctly on startup. Most people will not want this feature, and they should just leave it off.


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No, no, I think it was, "take five steps in any direction and you're screwed."
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Well, I mean her psychic had a lot of appointments.
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It's important to be just salty enough, really.
Hey, you know we all like to watch.
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HYDERABAD: People holding accounts with a post office can now operate their accounts from any other post office and also online. The department of posts, AP Circle, launched Core Banking Services (CBS) on Thursday, offering online banking, mobile banking and SMS alerts. ATMs will be opened in another six months.
The services can be availed at 82 of the 95 Head Post Offices located in the sibling states of Andhra Pradesh and Telangana, and the remaining 13 also will be shifted to the CBS platform by the first week of February.
Inaugurating the Core Banking Services, BV Sudhakar, chief postmaster-general, AP Circle, said that they would be enabling the CBS through 2,438 Sub Post Offices by June this year. ATMs will be opened in another six months.
He said post offices would also offer cashless service. People can use debit cards of any bank to draw cash up to Rs 1,000 at 63 post offices. Areas where there are no banks or ATMs will be given priority to launch the service.
NIRANTARA SEVA: To assist transportation of medicines from district headquarters to primary health centres in remote places in 13 districts of Andhra Pradesh, the department has provided 13 vehicles which will be kept at the disposal of the state's health department. "We expect a revenue of Rs 2 crore a year from this service," Sudhakar said.
Initially, the vehicles will ply on around 15 routes in each district.
TTD TICKETS: Apart from selling special entry darshan tickets of Tirumala Tirupati Devasthanams (TTD) at post offices, the department also intends to provide online booking of rooms and other services and the TTD is examining the proposal.
"Those wanting to book the darshan tickets have to be present in person at the post office while booking," Sudhakar said.


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Barbers Barnsley
Barbers in Barnsley (Results 1 - 20 of 46)
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- The Barbers Chair Ltd36 ROCHESTER ROADS71 2NJ Barnsley 07876 797 119
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- Mikes Barber Shop208 Sheffield RdS70 4PG Barnsley 01226 241052
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- Request for QuotationAre you looking for Barbers ?Use our 'Request for Quotation' service and get customized offers from companies in Barnsley.
- Sunshine Barbers Shop261A Doncaster RoadS70 3RH Barnsley 01226 299513Closed
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- Michael's Barber Shop16 Eldon Street NorthS71 1LG Barnsley 01226 215161
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- Bill Greenoff Hairdressing16C CROSS STREETS71 2EU Barnsley 01226 242 636Closed
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- Karl Smith Mens GroomingHanson StS70 2HZ Barnsley 01226 208555Closed
barbers using only the finest shave products. Colours and highlights are also available. All services are undertaken in our shop which can only be described as a gentleman's club meets old American...
- Rain Hair & Beauty Salon346, Sheffield RdS70 5TU Barnsley 01226 369620
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- The Barbers ChairAlhambra Shopping Centre, CheapsideS70 1SB Barnsley 07449 970611Closed
Barbers Chair now open on New Street Gent's hair cut £5 Beard Trim £2 Ladies trims from £7 Long hair (Ladies) from £9 All staff are fully qualified, professional hair stylists with 10-15 years...
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this was a gift for someone that was well worth it. As I have been told repeatedly since.. Unless its ghd its not a proper straightener.
heats up so quickly takes less than a minute I swear works like a dream. I love mine.
ghd is always a perfect choice for a straightener. I love this so much.
If you are looking for faster results, a hair straightening brush is more appropriate – it is a hybrid between a brush and a straightening iron, used best on dried hair and effective even for the most unruly naturally curly hair. You can use the straightening brush on hair that is washed and dried, and obtain the straightening iron results with much easier and intuitive brushing move.
Lovely item the usual excellent quality from ghd
I have spent years and years looking for the ultimate set of straighteners but have always resisted the ghd's because of the price but I finally gave in and ordered a pair this sunday and they arrived today I can assure anyone that these are the real thing the serial number has been authenticated by the official ghd website. As for the results wow my hair has never felt or looked so good and I have fine curly frizzy hair I have even washed the car and guess what no frizz or curls please order them you seriously won't be disappointed
works like a charm
When it comes to straightening, the hair color doesn't matter so much. Its thickness and health are way more important. If you have such a question, you may be one of the girls out there who have African American hair or Asian hair. Your hair is probably dense, thick, and hard to tame. For styling it, you need a flat iron that can maintain high temperatures. Other features depend on your hair length and health.
This straightener is awesome especially if you travel. Unlike the chi you do not need a converter in europe. Just plug in an adapter and you are set
After I wore out the brushes on the first two, I was looking for another brand that might have a better, longer lasting brush. I found the Hot Revolver by Martino Cartier. This was a very poor product and extremely overpriced. The brush would not glide through my hair and it was worthless for smoothing. The brush started to "click" and would no longer spin while in my hair. Terrible product.
Getting gorgeous hair at home is now within reach, thanks to professional-quality hair styling tools from ghd. The pros at ghd have made it their business to help ensure you have a great hair day every day. And with their revolutionary range of hair straighteners, styling devices, and more available at QVC, you can enjoy stunning styles without taking a trip to the salon.
pricey yes but what can I say daughter swears by ghd's no substitute no point buying cheaper brands. If she's happy then so am i. Her second paid of ghd's in 10 years so good value.
The mysterious product that smells earthy and looks like wet sand… is good for your hair? The answer is: YES! Think of it this way; the more natural smelling, the more natural the ingredients. Clay products DO contain clay, mostly what's called bentonite clay, which has highly absorbent properties. Clay is best used for building volume, absorbing oil and grease and drawing out impurities that can cause HAIR LOSS! Barbers choose to style with clay over other products because of its clean feel, density and ability to sculpt super flexible hairstyles. Clay products are NOT sticky, which you will find in some waxes and pomades.
after reading review with titles like fake I was a bit nervous but took a gamble anyway. Its authentic. I also found out that ghd has outsourced the production of some of there irons to china. In fact when I went to register my iron I clicked the help link for the date code and the example label had made in china clear as day on it.on the iron amazing night and day with the old one my favorite feature is the no tangle swivel cord
Not my first ghd. Very happy with both of them. My last one quit so I'm hoping this one lasts longer.
Hair breakage is an all too common problem, and even the most seasoned of hair stylists can slip up from time to time. That's why LumaBella's Keratin Duel Touch Hair Straightener features a unique smart heat sensor. This nifty little gadget can actually tell when there is too much heat for your hair, and will automatically adjust to a safer styling temperature!
For the last 12 years I've been saying I don't need ghd's my hair is straight already. And my 20 cheap straightens work just as well bough these during the prime day sale. And I can't believe I've lived all this time with out them. So smooth. And been able to make styles I've only dreamed of before.
Perfect for all hair typesincluding curls, fine, thick, long, short, extensons, wigs, or weavesTangle Teezer's Compact Styler helps reduce hair loss and cuticle damage. Offering pain-free detangling for wet and dry hair, you can use this in the shower to brush through conditioning treatments. The patented teeth formation bends and flexes through the hair, while the convenient clip-on/off cover protects teeth when in your luggage, gym bag, or handbag. Plus, the ergonomically designed shape fits snugly in your palm for creative styling and easy handling.
I was told by my stylist to get this flat iron because my chi was totally worn out. I was a little skeptical after reading reviews that some were fakes but I ordered the sold by amazon one and I was able to register it at ghd's website. I am definitely so happy that I chose to get this styler. It is awesome. It's the one and done styler. I don't have to keep going over and over my hair to get it straight so I know it's better for my hair overall. Plus you can't beat the fact that it turns itself off after 30 minutes. It takes away my did I remember to turn it off fear every time I left the house after straightening my hair. I also have really curly hair and this makes my hair soft smooth and shiny. Definitely recommend
as expected
There is a real risk of damaging your hair if you use a flat iron or hairbrush straightening tool on wet hair (or even damp hair if you have thin hair and are not extremely careful). The quick application of heat on wet hair brings the water within the hair follicle to a quick boil, the bubbles are then pushed out resulting in split ends and cracks in the hair. At the same time, essential vitamins and minerals are forced out which further adds to the problem, reducing the hairs natural elasticity which can lead to further brittleness and breakages. All of these issues can be further compounded if you have any residual product in your hair (especially any products containing alcohol) as these chemicals are boiled into the hair follicle.
Professional styling tool product reviewghd classic one inch flat ironthe ghd flat iron is a high performance professional styling tool. This is the original classic styler that is perfect for straightening and curling all hair types and lengths.features of product • ceramic plates for smooth hair• automatic shut off after 30 minutes of use• reaches a 350 to 365 degree temperature in under 40 seconds• rounded barrel• 8 foot styling cordpro's • 2 year manufacturer's warranty• guaranteed product authenticity• secure online payments• ordering tracking is availablecon's • no heat control but preset temperature does not burn hair• high cost but is also a high quality producti purchased my ghd straightener in december of 2013. It still works just as well as the first day I bought it. It is a very quality and reliable flat iron that holds up to its award winning standards. Since buying this product I have noticed more shine to my hair as well as little to no frizzing. It is effective in keeping my hair straight and smooth all day. In fact I have had friend's use this styling tool and purchase it after using it because they loved how quick and easily it flat ironed their hair.before I purchased the ghd I used a chi flat iron compared to a chi straightener the ghd keeps my hair looking healthier and less dry. After using this product I would not return to using a chi straightener because of the positive effect the ghd has had on my hair. Although the cost is high it delivers the promised performance. This product is designed for men and women with thick and curly hair looking to straighten their hair in a fast and healthy way. I would highly recommend this product to anyone that flat iron's his or her hair on a regular basis
great ghd styler . Very happy with them
I had this hair styler when it was first released and when mine finally died I was distraught as I could not find it, or anything like it, locally. When I finally found it on Amazon, I was so relieved! I am so happy to have this as it works great for me. My hair is short but I think your hair length is irrelevant. My hair is not curly but it has body and is a little coarse. When it rains or I am in a humid environment, it will frizz a bit. This hot air styler--which does away with the need for a separate brush--works perfectly to smooth out my hair and at the same time add volume and direction to my hair. A friend saw me using it at the beach recently and wanted to get one too. It ... full review
Short hair for fashionable men was a product of the Neoclassical movement. Classically inspired male hair styles included the Bedford Crop, arguably the precursor of most plain modern male styles, which was invented by the radical politician Francis Russell, 5th Duke of Bedford as a protest against a tax on hair powder; he encouraged his frends to adopt it by betting them they would not. Another influential style (or group of styles) was named by the French "à la Titus" after Titus Junius Brutus (not in fact the Roman Emperor Titus as often assumed), with hair short and layered but somewhat piled up on the crown, often with restrained quiffs or locks hanging down; variants are familiar from the hair of both Napoleon and George IV of England. The style was supposed to have been introduced by the actor François-Joseph Talma, who upstaged his wigged co-actors when appearing in productions of works such as Voltaire's Brutus (about Lucius Junius Brutus, who orders the execution of his son Titus). In 1799, a Parisian fashion magazine reported that even bald men were adopting Titus wigs,[18] and the style was also worn by women, the Journal de Paris reporting in 1802 that "more than half of elegant women were wearing their hair or wig à la Titus."[19]
At the price of a coffee and sandwich, you will be over the moon with the Revlon 5265CU Shape and Smooth Air Styler. It boasts 108 Amazon customer reviews with combination of 74 at 4 or 5 stars; I believe this is an excellent low cost air styler. I would buy one of these just as a spare or to carry round as it is also lightweight so makes for a good travel solution.
During this period, Western men began to wear their hair in ways popularized by movie stars such as Douglas Fairbanks, Jr. and Rudolph Valentino. Men wore their hair short, and either parted on the side or in the middle, or combed straight back, and used pomade, creams and tonics to keep their hair in place. At the beginning of the Second World War and for some time afterwards, men's haircuts grew shorter, mimicking the military crewcut.[30]
love this straightener. Heats up in no time and makes my hair nice and silky. No burnt smells. And has auto shut off.
There are less expensive stylers but if you use one everyday you want one that works very well.this one works great. It's well built to begin with. The grip is easy to hold and it springs open when you aren't clamping it. There's a very long 9 foot cord and unlike any others I've seen it connects to the styler with a swivel. That makes it easy to maneuver especially for styling someone else's hair if you need to walk around them and go at it from all sides. The other thing that makes this extremely useful is how quickly it heats up and is ready to go. Turn it on and it beeps and then in under half a minute it beeps again twice signaling it is ready.you can straighten hair very quickly and it does an impressive job. Curling is easy too whether you go for tight curls or wavy hair.if you leave it sitting and forget to turn it off it shuts off automatically after half an hour. I almost think that it would be better to shut off after 15 minutes inactive. Given how quickly it heats up that wouldn't be a bother if you happened to step away too long inadvertently. Easy to use built to last and built safe this heats up quickly and does a good job.
Getting gorgeous hair at home is now within reach, thanks to professional-quality hair styling tools from ghd. The pros at ghd have made it their business to help ensure you have a great hair day every day. And with their revolutionary range of hair straighteners, styling devices, and more available at QVC, you can enjoy stunning styles without taking a trip to the salon.
My hairdresser really rates ghd products saying they know about hair and make sure their products style without causing damage. Everything about the ghd styler speaks of quality and a lot of attention to detail. The blue accented shoebox outer packaging is pretty enough to use for long term visible storage a heat resistant mat wraps around the storage bag and the straighteners themselves have metallic icy blue accents bringing the whole thing together into a coordinated package.heating up time is fast at a few seconds with a helpful 'beep' sounding at switch on accompanied by a flashing light. You are alerted to full heat attainment by further beeps and a constant light. A full head of curly tending towards frizzy shoulder length hair was straight within a couple of minutes.the cord length was ample for my requirements and the straighteners proved easy to use. The plates made short work of the task and a useful silicone guard safely holds the plates together once you're done. Everything then packs neatly away into a storage bag which has a divider to ensure the lead and plug remain separate to the styler and around which the heat resistant mat clips into place.in summary• fast heat up time of a few seconds• beeps to alert once ready for use• easy to use with a generous lead• simple on off switch no temperature control needed • heat resistant mat and storage bag• silicone guard to hold the plates closed for easy storagethis would make a beautiful gift whether to self or another delivering both practicality and icy good looks.
just received these as my first ghds and I'm amazed just how fantastic they are. They've straightened my shoulder length hair so quickly and better than any others I have tried. If you're thinking about getting these do it you won't regret it.
although they are selling a red version on their own website today for slightly less. So if you thought this was too cheap to be an authentic product don't worry. It isn't.
I am so happy since I bought my ghd. I should have bought it before. It is so easy to work with it love it
The titanium plates in the BaByliss Pro Nano Titanium Straightening Iron were designed to conduct high levels of heat (again, up to 450° F!) in a short amount of time. Coupled with the Nanotechnology that is packed in each plate, this hair straightener is ideal for anyone that experiences unwanted frizz or static on a regular basis! The titanium also acts as a barrier from corrosion keeping your hair straightener and precious strands free of build-up for years to come!
Featuring advanced ceramic heat technology, the ghd Gold Professional Performance 2" Styler is designed to operate at the optimum 365°F styling temperature for healthy-looking hair with enhanced, lustrous shine. Styling thicker, longer hair is quicker and easier thanks to the larger plates that glide through strands without snagging for fast, effortless styling and flawlessly polished strands. It heats up in as little as 30 seconds to tame frizz and transform coarse textures into sleek, smooth styles that last. The styler has contoured, round edges to unleash undulating waves, and with its styling versatility, you can change your look every day.
Eight embedded sensors regulate and evenly distribute the heat on this ceramic iron, minimizing damage and increasing shine and smoothness. With adjustable temperature settings that go as low as 140 degrees (the coolest we've ever seen), it's ideal for anyone with super fine hair, or to smooth out the tiny frizzies around your hairline. It also comes with a lifetime warranty, which is never a bad thing.
I ordered these straighteners as I'd had a pair before that lasted me 7 years it takes only 10 minutes to straighten my long hair and I would highly recommend these to anyone. These straighteners were also fantastic value for ghds which are usually over 100. They were extremely well packaged and arrived in perfect condition I am over the moon
I was a bit worried with buying a ghd hair straightener over the internet and I thought the cheaper price was too good to be true but I was able to do some research and was delighted to discover that the ghd I was sent was a genuine product it works great.
We have scoured through the natural hair scene to narrow down the options. Based on popularity, quality of ingredients, and overall effectiveness, our top 10 hair stylers collection was born. Not surprisingly, this collection features some of the most beloved brands on the scene such as EDEN Bodyworks, Carol's Daughter, Aunt Jackie's, and more. Of course, no collection is complete without the constant favorite of Ecoco! We offer only the best formulas in this collection to give your curls the hold and styling help they need to pull off any look with ease. While gels and pomades are important for laying perfect edges and achieving that sleek look, we also include other options in this collection of top natural hair stylers.
Love love my ghd I ordered this to replace my last ghd that had lasted me 7 years I love the quality and way it styles my hair.
In the middle of the 18th century the pouf style developed, with women creating volume in the hair at the front of the head, usually with a pad underneath to lift it higher, and ornamented the back with seashells, pearls or gemstones. In 1750, women began dressing their hair with perfumed pomade and powdering it white. Just before World War I, some women began wearing silk turbans over their hair.[14]
this has become my favorite flat iron yet. Heats up very quickly gets the job done and is very lightweight. Worth the price
Given its tiny stature, it is no surprise that the BaByliss Pro Nano Titanium Straightening Iron is ideal for users with short or medium hair lengths. Unlike the more industrial models we reviewed that are designed for longer or thicker hair, this BaByliss hair straightener is small and light enough to polish off a short bob or shoulder-length style in no time.
The L'Oréal Professionnel Steampod is unique in that unlike traditional hair straighteners, it relies on steam technology to straighten hair; reducing frizz and smoothing down the fibres. This technology provides gentle heat action which helps to minimise damage to the hair. Proven to be faster than other straighteners and giving up to 50% smoother hair, the Steampod is perfect for enhancing your blow-dry and giving you salon-perfect results each and every time.
This feature is particularly beneficial for users with naturally wavy or curly hair, which can have a tendency to easily snag in hair styling tools. This floating design, combined with the heat sensor, also ensures that your gorgeous curls won't become permanently damaged just because you decide to straighten things out a bit for an evening or two. After all, those curls are coveted by beauty pros the world over, and you never want to damage them just because of a styling trend!
I love ghd products. This is the only flat iron I will use on my hair. My last ghd lasted me 6 years. It still works ok because the every day abuse I gave it and I keep it as a back up .worth the money.
this straightener is amazing. It heats up in about 20 seconds and is slim and does it's job perfectly. I tell all of my friends about it
During this period, Western men began to wear their hair in ways popularized by movie stars such as Douglas Fairbanks, Jr. and Rudolph Valentino. Men wore their hair short, and either parted on the side or in the middle, or combed straight back, and used pomade, creams and tonics to keep their hair in place. At the beginning of the Second World War and for some time afterwards, men's haircuts grew shorter, mimicking the military crewcut.[30]
I was told by my stylist to get this flat iron because my chi was totally worn out. I was a little skeptical after reading reviews that some were fakes but I ordered the sold by amazon one and I was able to register it at ghd's website. I am definitely so happy that I chose to get this styler. It is awesome. It's the one and done styler. I don't have to keep going over and over my hair to get it straight so I know it's better for my hair overall. Plus you can't beat the fact that it turns itself off after 30 minutes. It takes away my did I remember to turn it off fear every time I left the house after straightening my hair. I also have really curly hair and this makes my hair soft smooth and shiny. Definitely recommend
Wife having as replacement after 5 years using first one ghd.
Absolute best flat iron on the market they last for years so it's totally worth the investment
I have been coveting one of these stylers since I borrowed a friend's in the uk in 2007... And I finally got one and it's an authentic one I suspect amazon's prices are low to compete with all of the vendors selling fakes on here which is a shame for them but worked out just fine for me. Make sure you select the one that's shipped from and sold by amazon the main page for this product seems to rotate between several vendors not all of them trustworthy and right now I have to check the little more buying choices sidebar to find the one sold by amazon itself. They were the main vendor for this page when I ordered but they're not now so it looks like it changes out.i was able to register mine with ghd's website and everything looks feels like the quality you'd expect from something that usually retails for almost twice what you'll pay for one here so I'm pretty positive it's legit.i've been using a chi for the last 8 years. The same chi. It's held up well clearly and still works but it just doesn't heat like it used to and its time has been up for a while now. It's served me well I'd read some reviews in several places saying that their quality had dropped off and I still remembered how wonderful the ghd I'd tried had been and that was when my chi was still in its prime so in looking to replace my straightener I really wanted to see if I could find an authentic ghd at a reasonable price. And I did I've only had my ghd for a few days now so I can't attest to its longevity I somehow doubt anything will ever compete with its predecessor on that front anyway but it works like an absolute dream. The first time I turned it on I was sure something wasn't working quite right because it gave me the all heated up beep so rapidly under 15 seconds. But no. Ready to go. It slid through my hair like butter leaving nothing but smoothness in its wake. My ends don't feel all frazzled like they do when I use cheaper straighteners and I can get pretty substantial waves out in a single pass with minimal styling product. And it goes into sleep mode after 30 minutes which is wonderful did I leave the hair straightener on is my personal equivalent of the old did I leave the gas on worry.a fantastic product for an excellent price and I couldn't be happier. Just choose your vendor wisely and make sure to check authenticity on their website
Makes my hair much shinier than my lower end flat iron about 30 range . I have wavy hair which straightens easily but will often gain wave as the day goes on. This makes my hair stay straight through the night and into the next day. Heats up fast and has the great option to use for curls waves. Mine was verified by ghd as authentic when I registered it.
My ghds finally broke after over 10 years so bought a new set still as good as they always have been
Bought these at a very reasonable price and they are great.they arrived within the week of ordering them which was also great.
The ceramic plates on this hair straightener ensure that hair remains glossy and nourished even through the high-level of heat. A brilliant all-rounder for quick and effortless everyday styling, the ghd IV Hair Straightener can create both smooth locks and curls; making it a great multi-tasking product. Suitable for all hair types and lengths, the styler glides smoothly through the hair in one gentle action so snagging is reduced.
A fabulous duo of top notch ghd products. Firstly the styler it's easy to use as it automatically heats to a predetermined non adjustable 185 c optimal for styling without damaging hair. Should one need a higher temperature then this is not for you. It's supplied with a chunky 20 cm square heat mat to protect surfaces and it auto powers off after 30 minutes if not in use. Given its speedy heat up rate I reckon this could be reduced to 10 minutes in use great results are possible with very little practise.and the hairdryer very nicely balanced with good access to the controls without stopping. The lower switch is the 3 position fan speed off medium high but it doesn't sit quite right ... To get to the highest speed one has to push the end of the switch down into the handle its as though the switch has not been installed level vertical but it's not a huge problem the 3 position heat switch is much better. The cold shot button requires a fair bit of effort to hold in with 1 finger for anything more than a few seconds.both have very good quality cable that are properly flexible unlike some 2.7 m styler 3.0 m on the dryer. With regard to cables the manufacturer's make it clear that the cables should not be wound around the device but folded as they were as they came out of the box ... That's ok in theory but using the twist ties is not practicable so it would have been useful to include some cheap and easy method of coiling the cable especially for travelall said and done superb kit with a niggle about a switch and cable storage
amazing styler curls my stubborn hair perfectly


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Breaded shrimp recipes
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text: Partners learn at Bains Lower Staff report Advocate Staff Author email Nov 22, 2019 - 2:30 pm 1 min to read Facebook Twitter SMS Email 1 of 2 Brighton Tilley and Dakota Linkous are learning partners at Bains Lower Elementary. Provided photo Jillian Brown and Tallan Guerra learn about numbers as partners at Bains Lower Elementary. Provided photo Facebook Twitter SMS Email Print Save Bains Lower Elementary students learn with partners during many classroom assignments. Facebook Twitter SMS Email Print Save Advocate Staff Author email Follow Advocate Staff Close Get email notifications on {{subject}} daily! Your notification has been saved. There was a problem saving your notification. {{description}} Email notifications are only sent once a day, and only if there are new matching items. Save Manage followed notifications Close Followed notifications Please log in to use this feature Log In Don't have an account? Sign Up Today View comments Follow Us Facebook Twitter Instagram Email


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Archive for November, 2010
The Bodybuilder
by Mr. Mandelbrot on Nov.09, 2010, under General, Images
There is one image that is similar to this "person" done in UF a long time ago, but it's more like a boxeur ready for a fight. This one is just a strong guy. Done with Mandelbulb 3D.
Related Images:
Mandelbulb mountains
by Mr. Mandelbrot on Nov.06, 2010, under General, Images
Some more stuff done with Mandelbulb 3D. Much probably as I'm late with the software everything I'm seeing and doing has been done already to death, but who cares. Also I'm starting to use a new watermark. I'm glad to see that the length of the visits are getting much longer, which means people are actually spending some time viewing my fractals. Thanks.


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Issues & Trends
|The rise of electric cars could leave us with a big battery waste problem
Carmakers, recyclers and tech startups are working to solve the question of how to deal with lithium-ion batteries when they wear out
|Plummeting insect numbers 'threaten collapse of nature'
Exclusive: Insects could vanish within a century at current rate of decline, says global review
|Monarchs 2018
Looking for good news? Last summer we were so pleased to see so many Monarchs in Pennsylvania and New York, more than we have seen in a decade. Eagerly awaited number of over-wintering population in Mexico confirms this impression. See updated graph below, and link to an article in the Guardiian.
|Sea Level Rise Will Flood Hundreds of Cities in the Near Future
Many shore communities in the U.S. face inundation in the coming decades.
|'Eat Less Meat Or Pay The Environmental And Human Price', Says UN
It says meat production is 'one of the most destructive ways in which we leave our footprint on the planet'.
|Global warming has changed the Great Barrier Reef 'forever,' scientists say
Two years after a long-lasting undersea heat wave scalded large sections of the Great Barrier Reef, scientists have found that because so many corals died, much of the reef has probably been altered "forever."
|The world's bleak climate situation, in 3 charts
We're currently heading for around 3 degrees of warming
Global average temperatures have risen about 1.1 degrees Celsius since preindustrial times. At current rates, they could exceed 1.5 degrees by 2030. And global greenhouse gas emissions, after a brief lull from 2014 to 2016, are rising again.
|New maps show the utterly massive imprint of fishing on the world's oceans
Humans are now fishing at least 55 percent of the world's oceans — an area four times larger than the area occupied by humanity's onshore agriculture.
|Can Planet Earth Feed 10 Billion People
All parents remember the moment when they first held their children—the tiny crumpled face, an entire new person, emerging from the hospital blanket. I extended my hands and took my daughter in my arms. I was so overwhelmed that I could hardly think.
|Research Highlight: Acid Ocean Poses Increased Reef Loss Risk
Scripps researcher Tyler Cyronak and test chambers in a study of ocean acidification effects on coral reef sediments in Bermuda
Much of the sediment that serves as the foundation of most coral reef ecosystems could begin to erode within 30 years as a result of increasing ocean acidity, according to new research.


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Shatarudriya, aka: Śatarudriya, Śatarudrīya, Shata-rudriya; 4 Definition(s)
Shatarudriya means something in Hinduism, Sanskrit. If you want to know the exact meaning, history, etymology or English translation of this term then check out the descriptions on this page. Add your comment or reference to a book if you want to contribute to this summary article.
The Sanskrit terms Śatarudriya and Śatarudrīya can be transliterated into English as Satarudriya or Shatarudriya, using the IAST transliteration scheme (?).
In Hinduism
Shaivism (Shaiva philosophy)
Śatarudrīya (शतरुद्रीय):—It is also said that gods are satiated if Śrī Rudram is chanted and hence it is also called Śatarudrīya, which means extolling one hundred ways of glorifying Rudra.Source: Manblunder: Sri Rudram Introduction
Shaiva (शैव, śaiva) or Shaivism (śaivism) represents a tradition of Hinduism worshiping Shiva as the supreme being. Closely related to Shaktism, Shaiva literature includes a range of scriptures, including Tantras, while the root of this tradition may be traced back to the ancient Vedas.
Purana and Itihasa (epic history)
Śatarudrīya (शतरुद्रीय).—A portion of the Vedic (Yajus) literature except which the Trayī exists until the pralaya;1 here the Rudras partake of the offerings;2 sacred to pitṛs;3 Citrakarma, the Gaṇeśvara taught this to Madana;4 japa at Benares leads one to eternal beatitude;5 identified with Śiva.6
- 1) Vāyu-purāṇa 59. 57.
- 2) Brahmāṇḍa-purāṇa II. 9. 84.
- 3) Matsya-purāṇa 22. 35.
- 4) Brahmāṇḍa-purāṇa II. 32. 63; IV. 7. 49; 11. 30-33; 34. 52.
- 5) Matsya-purāṇa 184. 56.
- 6) Vāyu-purāṇa 30. 244.
The Purana (पुराण, purāṇas) refers to Sanskrit literature preserving ancient India's vast cultural history, including historical legends, religious ceremonies, various arts and sciences. The eighteen mahapuranas total over 400,000 shlokas (metrical couplets) and date to at least several centuries BCE.
General definition (in Hinduism)
The Śatarudriya (शतरुद्रिय), constituting the sixty-six subdivisions of chapter 16 of the Vājasaneyi-saṃhitā, is a litany accompanying no less than 425 oblations and addressed to the hundred forms and powers of the god Rudra.Source: Springer: The Śatarudriya
Languages of India and abroad
Sanskrit-English dictionary
Śatarudriya (शतरुद्रिय).—
1) a Vedic text (rudrādhyāyaḥ -'namaste rudramanyave' iti yājuṣaḥ prapāṭhakaḥ); गृणन्तौ वेदविद्वांसौ तद्व्रह शतरुद्रियम् (gṛṇantau vedavidvāṃsau tadvraha śatarudriyam) Mb.7.81.13;7.22.12.
2) a particular Śiva-stotra in the Mahābhārata; देवदेवस्य ते पार्थ व्याख्याः शतरुद्रियम् (devadevasya te pārtha vyākhyāḥ śatarudriyam) Mb.7.22.48.
Derivable forms: śatarudriyam (शतरुद्रियम्).
Śatarudriya is a Sanskrit compound consisting of the terms śata and rudriya (रुद्रिय).Source: DDSA: The practical Sanskrit-English dictionary
Sanskrit, also spelled संस्कृतम् (saṃskṛtam), is an ancient language of India commonly seen as the grandmother of the Indo-European language family. Closely allied with Prakrit and Pali, Sanskrit is more exhaustive in both grammar and terms and has the most extensive collection of literature in the world, greatly surpassing its sister-languages Greek and Latin.
Relevant definitions
Search found 293 related definition(s) that might help you understand this better. Below you will find the 15 most relevant articles:
Śaṭa (शट).—mfn. (-ṭaḥ-ṭā-ṭaṃ) Sour, astringent, acid. E. śaṭ to pain, aff. ac .--- OR --- Śaṭā ...
Śataghnī (शतघ्नी).—assumed by Senart to mean scorpion (so Wilson and Apte, no reference(s) in t...
Śatānīka (शतानीक).—m. (-kaḥ) 1. An old man. 2. The name of a sovereign, the son and successor o...
Śatānanda (शतानन्द).—m. (-ndaḥ) 1. Brahma. 2. Vishnu or Krishna. 3. The car of Vishnu. 4. The M...
Śatadru (शतद्रु).—f. (-druḥ) The river Sutlej, which rises in the Himalaya mountains in the vic...
Śatamāna (शतमान).—mn. (-naḥ-naṃ) 1. A pala of silver. 2. An Adhaka or measure so termed. E. śat...
Śatahradā (शतह्रदा).—f. (-dā) 1. Lightning. 2. The thunderbolt. E. śata a hundred, hrada a ray ...
Śatakumbha (शतकुम्भ).—n. (-mbhaṃ) Gold. m. (-mbhaḥ) The name of a mountain. f. (-mbhā) A plant,...
Śatapuṣpa (शतपुष्प).—n. of a former Buddha: Mv iii.231.10.--- OR --- Śatapuṣpā (शतपुष्पा).—n. o...
Śatapadī (शतपदी, "myriapod") represents an incarnation destination of the tiryaggati (animal re...
Śatapatra (शतपत्र).—n. (-traṃ) A lotus in general, (Nelumbium speciosum or Nymphæa nelumbo.) m....
Śatarūpā (शतरूपा).—Wife of Svāyambhuva Manu, who took his sister Śatarūpā herself as his wife. ...
Śatabhiṣā (शतभिषा).—f. Name of the 24th lunar mansion containing one hundred stars. Śatabhiṣā i...
Śatakratu (शतक्रतु).—m. (-tuḥ) Indra. E. śata a hundred, kratu sacrifice; a hundred Ashwa-Medha...
Śatadhāra (शतधार).—mfn. (-raḥ-rī-raṃ) 1. Flowing in many streams. 2. Having many edges. n. (-ra...
Relevant text
Search found 11 books and stories containing Shatarudriya, Śatarudriya, Śatarudrīya or Shata-rudriya. You can also click to the full overview containing English textual excerpts. Below are direct links for the most relevant articles:
The Garuda Purana (by Manmatha Nath Dutt)
Chapter CCXLVIII - The eight essentials of Yoga, etc. < [Dhanvantari Samhita]
Satapatha Brahmana (by Julius Eggeling)
Kāṇḍa IX, adhyāya 1, brāhmaṇa 1 < [Ninth Kāṇḍa]
Kāṇḍa IX, adhyāya 1, brāhmaṇa 2 < [Ninth Kāṇḍa]
Kāṇḍa X, adhyāya 3, brāhmaṇa 4 < [Tenth Kāṇḍa]
Lalitopakhyana (Lalita Mahatmya) (by G.V. Tagare)
Chapter 13 - A hymn in praise of Lalitā
Chapter 11 - The appearance of demon Bhaṇḍa
Chapter 34 - The Region of Śiva and of the guardians of quarters
The Shiva Purana (by J. L. Shastri)
Chapter 8 - Bhairava incarnation < [Section 3 - Śatarudra-saṃhitā]
Chapter 14 - Directions for the worship of Śiva < [Section 2.1 - Rudra-saṃhitā (1): Sṛśṭi-khaṇḍa]
Chapter 20 - Worshipping an earthen phallic image by chanting Vedic mantras < [Section 1 - Vidyeśvara-saṃhitā]
The Padma Purana (by N.A. Deshpande)
Chapter 34 - The Greatness of Kṛttivāseśvara < [Section 3 - Svarga-khaṇḍa (section on the heavens)]
Chapter 111 - The Sinner Vidhṛta Goes to Śiva's Abode < [Section 5 - Pātāla-Khaṇḍa (Section on the Nether World)]
Chapter 53 - Rules of Conduct for a Celibate Student < [Section 3 - Svarga-khaṇḍa (section on the heavens)]


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Santa Steam Trains
Travel on the Bo'ness & Kinneil Railway. Santa travels by Steam Train, giving a gift to each of the young passengers. Christmas decorations and Christmas songs create a festive atmosphere. Adults receive seasonal refreshments at Bo'ness station. Special timetable; Advance Booking Essential.
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