text: Pediatric fellowships provide home-grown solution to physician shortagesPublished on Monday, September 28, 2015By: Alana Bowman at 601-984-1970 or firstname.lastname@example.com. Published in News Stories on September 28, 2015 No parent wants to hear the words "your child needs to see a specialist," then hear that the next available appointment is two months away. This is a problem facing parents and kids nationally - a shortage in pediatric subspecialists. According to the Children's Hospital Association (CHA), the most severe pediatric shortages are in neurology, developmental/behavioral medicine, gastroenterology, surgery and neurosurgery.Barr"Certain pediatric specialists are always hard to recruit. This isn't just Mississippi. It's everywhere," said Dr. Rick Barr, Suzan B. Thames Professor and chair of pediatrics. "We aren't producing enough pediatric specialists nationally to meet the need - probably aren't producing enough to keep up with the retirement of physicians."Subspecialist shortages mean a longer than average wait for an appointment - up to 14.5 weeks, when a two-week wait is considered normal. Patients often must travel long distances to keep these long-awaited appointments. The American Academy of Pediatrics reports that one in three children in the U.S. travel 40 or more miles to see a pediatric specialist.Recruiting pediatric specialists can be a difficult task for several reasons. Becoming a subspecialist requires additional training beyond specializing in pediatrics. And according to the CHA, the subspecialists' income can also be lower because they provide more consulting services than daily patient care in a clinical setting, and Medicaid pays 30 percent less than Medicare for services. Half of Mississippi's children are covered by Medicaid.Hematology/Oncology fellows, Dr. Laura Newman, left, Dr. Hafsat Mashegu and Dr. Amanda Strobel, visit the bedside of oncology patient Andrew McCall of Philadelphia, Miss.Being able to train specialists from candidates who are already settled in Mississippi and call it home can lessen the uncertainty of recruitment. "Fellowship programs tie directly into our mission: improving child health in Mississippi. It is incredibly important to be able to grow your own," said Barr.Although some pediatric residents show an interest in seeking further specialized training, Barr said they are hesitant to move away for a fellowship in another state. "They want to stay in Mississippi. They have family ties here and don't want to move away for the three-year training process. If they do, sometimes we have trouble recruiting them back because they get established in the new area."Although Children's of Mississippi operates satellite locations in Tupelo, Grenada, Hattiesburg and on the Gulf Coast, most of Mississippi's pediatric specialists are located in the Jackson area. Barr would like to see that change. "That's the rationale for all of our fellowship programs, train specialists for the state and have them branch out throughout the state to provide care. If we can grow our own, I can make sure we are serving the entire state."Dr. Radhika Narang, right, neonatal-perinatal fellow, rounds in the NICU with residents Dr. Edward Landry and Dr. Diana Tate.Regulated by the Accreditation Council for Graduate Medical Education, fellowships are approved and monitored in a way similar to residency programs. Barr said that the school must have enough board-certified faculty to provide a well-rounded educational experience for the fellows. The training in any pediatric subspecialty is three years long, with both clinical and research aspects."We are training people to ask questions, to really contribute new knowledge to the field," said Barr.Barr said a division has to have a game plan when deciding to pursue a fellowship accreditation. "We built the capacity over the past four years. We have the infrastructure in place with qualified research mentors and challenging projects that can translate into improved health for our patients."The ACGME accredited the new gastroenterology fellowship program in May of this year. In July 2016, the school will welcome its first pediatric gastroenterology fellow, adding an additional fellow each year to bring the total to three.Currently, the School of Medicine has pediatric fellows training in allergy, cardiology, critical care, hematology-oncology, neonatology, neurology, pediatric surgery and palliative care.TipnisDr. Neel Tipnis, division chief of pediatric gastroenterology, said that qualifying to host a fellowship is a source of pride for a medical school."I think that it says a lot about the quality of academics here with regards to both clinical exposure and the depth and diversity of the faculty," said Tipnis.Tipnis said that having a basic science researcher in the group, access to the vast network of researchers, academic programs, lectures and faculty who have published well all contribute to being able to host a fellowship.In the past five years, the department has grown from two pediatric gastroenterologists to six, one of whom is primarily a researcher. The department also has added a nurse practitioner, and a seventh physician will join the group at the end of October. Specialty areas of the team include motility, short bowel syndrome, liver transplant patients, childhood obesity and biofeedback.BleckerDr. Uwe Blecker, professor of pediatric gastroenterology, is the fellowship director for the new program. He arrived at Batson in July 2014 with the goal of starting a gastroenterology fellowship."Having a medical school-wide accredited education program, an established pediatric residency program and six other fellowships, there was a support system already in place," said Blecker.Blecker is pleased by the initial interest in the program, despite having missed this year's matching process to obtain fellows. "I received a significant number of inquiries about the fellowship program," said Blecker.The department will begin interviewing candidates in the fall.Dr. Jenna Dear, hospice and palliative medicine fellow, speaks with Dr. Rick Boyte, professor of pediatrics and division chief of pediatric palliative medicine at Batson Children's Hospital.


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Sleep Channel
Topics & Medications
Related Channels
ProSom Uses
ProSom is used for the short-term treatment of insomnia in adults. Studies have shown that it helps people fall asleep and stay asleep. As part of a group of medications known as benzodiazepines, ProSom works by affecting a certain brain chemical that produces a naturally calming effect. The medication has not been approved for use in children, and there are currently no off-label ProSom uses.
ProSom Uses: An OverviewProSom® (estazolam) is a prescription medication that is approved for treating insomnia. It is part of a group of medications known as benzodiazepines.
What Is Insomnia?For many people, it is not unusual to have trouble sleeping from time to time. However, if you feel that you do not get enough sleep or cannot obtain satisfying sleep, you could possibly have a sleep disorder called insomnia.
Symptoms of insomnia can include:
- Having trouble falling asleep at bedtime
- Waking up often during the night and having trouble going back to sleep
- Waking up too early in the morning
- Having unrefreshing sleep.
There are several types of insomnia. These types are often based on how long the insomnia lasts and how often it occurs. They include:
- Acute insomnia (short-term)
- Chronic insomnia (long-term)
- Transient insomnia (comes and goes).
Short-term insomnia can last from one night to a few weeks. It is often caused by physical or emotional discomfort, and can be related to a single specific event (see Insomnia Causes). About 60 million Americans each year experience insomnia.
ProSom is approved for the short-term treatment of insomnia, meaning that it should generally not be used for long periods of time.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD

subset: commoncrawl


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Cellular Gateways
Developer Kits
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Custom Cables
Novotech's value-added service offering includes:
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Can't find what you're looking for? Please email firstname.lastname@example.com or call 1-800-268-8628 for a free consultation with one of our sales representatives.


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You're ready to take the next step in your home buying journey and apply for your mortgage loan preapproval. Here, you can start the loan application process by following one of the links below:
Short Loan Application
This form should take only 5 minutes to complete and requires only the minimum amount of information that is necessary to start the loan process.
Complete Loan Application
This application should take approximately 15-30 minutes and requires information from personal documents to collect all of the information that will be necessary to process your loan.
Please contact one of our loan officers if you have any questions about either of these forms.


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Code: PRZ-WOPUmh4
This flat rental is located in Courchevel 1650, a world renowned ski resort with all the modern amenities and facilities it offers. The flat is suitable to 6 guests and can be a great accommodation for a get-together whether you're a family or a group of friends.
This rental boasts of a spacious lounge and dining area with bay windows opening out to a south facing balcony with a great view of the neighbouring Courchevel 1850. It also has a fully equipped kitchen for self-catered guests.
With more than 70 restaurants in Courchevel you can eat everything from a simple crepe for a few Euros to a seven course gourmet meal for over 100 euros. Courchevel has some excellent food shops ready to serve its discerning clientele with everything from the ingredients of an omelette to a gourmet meal.
Great Mountain Retreat in Courchevel 1650 is one of our France Luxury Rentals . View Guide to France Luxury Vacations
Disclaimer: Pins in map may not be accurate if Google Maps cannot find the exact address. In this case an approximation is made.
View Destination Guides: Courchevel, French Alps, Courchevel 1650
Courchevel 1650 offers a separate ski area which is much quieter than the higher slopes. There's a busy centre with shops, some excellent restaurants (notably Le Petit Savoyard, L'Eterlou and Montagne) and some great bars – all friendlier and much more affordable than what the rest of Courchevel has to offer. There are 3 lifts leading up from Courchevel 1650, providing convenient access to the challenging terrain, including the Ugly Sisters Couloirs, the off-piste, and of course, the other resorts of The Three Valleys.


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Welcome to Jersha & Dup!
I'm Jessica Holbrook, (aka Jersha). I'm a 28 year old woman who loves blogging, computers and technology, video games, photography, and learning new stuff. I'm a little sarcastic and I'm not afraid to tell it how it is. I've been working on Jersha & Dup for over 4 years now and I've seen it grow from humble beginnings to a respectable following. My favorite category on Jersha & Dup is product reviews because I love testing a product, weighing its pros and cons, and sharing whether I think it is worth buying. I also love writing about new experiences like trying the Konmari Method or going on a mini-vacation to a water park.
My husband is Phillip (aka Dup). He's 26 years old but he doesn't love blogging (I dragged him along for the ride). He loves geeky stuff like Dungeons and Dragons and Magic the Gathering, board games, video games, and new gadgets. He doesn't like to write so you'll mostly see Phillip in video reviews. Phillip is also into electronics tinkering so you may see him writing a Raspberry Pi tutorial or in an Arduino project video.
What to Expect on Jersha & Dup
Jersha & Dup is about our life. We post about lifestyle tips and tricks (like Konmari), great deals, craft projects, awesome websites I find, product reviews, new gadgets, tech and craft projects, and lots of other random stuff. Take a look around, the homepage is a great place to start. If you're a company with a product available for review, head on over to our media kit.
And hey, let's be friends! Tweet me @jershaanddup and say Hi!


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Great News, TransferPaperSupplies.com is positioned to be a premier provider of heat transfer vinyl, heat transfers, heat presses and accessories. We believe that by providing high quality products and our 50 combined years or garment decorating experience we will soon be your choice supplier.
When you're trying to decide who can do the best for you at the right price, there are several factors to consider. At HTS, we proudly model our organization in a manner that is professional, knowledgeable, and helpful.
In early 2000, TransferPaperSupplies.com opened its doors on 1810 N. Hercules Ave. Clearwater, Fl. 33765. With a grand plan to provide courteous service, extensive knowledge and outstanding products in the areas of garment decorating, we have grown from a small owner operated business in 2005 to a 30 person highly experienced individuals to help you. Our founder had a vision to become the premier trusted provider of garment decorating materials, equipment and accesories. We continue those ideas and values today.


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A blog about my adventures as a professional garden writer, radio show host and obsessive veggie gardener! My first book, the award-winning, The Year Round Vegetable Gardener, was published in 2012 and Groundbreaking Food Gardens hit shelves in March 2014!
Saturday, April 4, 2015
A sampling of the new All-America Selections winners for 2015
To be considered for AAS testing, plant breeders must enter new, never sold before, cultivars. I've grown AAS winners since I was a teenager, but this year, I have been asked to grow, evaluate and blog about some of the winners from the past five years. So last week, a big box of seeds arrived and I spent a happy hour pouring through the box, choosing what to grow. I ended up starting 8 flats of seeds, selecting a combination of vegetables, herbs and ornamentals. As the spring turns to summer, I will continue to blog about these award-winning plants and update you on their progress, successes and failures.
Here are a few of the 2015 All-America Selections Winners that I'll be growing in my garden this year. To see more of current and past award winners, just visit the AAS website.
I know you're going to think I'm weird, but sometimes when I'm feeling snacky, I crave broccoli! I'll steam up an entire head, sprinkle it with salt and devour it in mere minutes. Therefore I'm rather excited to try this new AAS award-winning broccoli.
Artwork is a stem broccoli, which means that the central head is just the opening act. After the initial crown is harvested, the plants begin to pump out side shoots for a long harvest of tender, bite-sized florets. The plants continue to produce stem (also called baby) broccoli for an extended period of time and are both heat and bolt resistant. I'm looking forward to testing this in my spring and early summer garden, but I also want to see how it fares for fall and winter harvesting.
This is the first lettuce to win and AAS award in 30 years!! Wow, it must be good.
Sandy is a green oakleaf type lettuce that produces tight rosettes of crinkly leaves that are mild and sweet. The plants are resistant to powdery mildew and bolting, which means they won't throw in the towel on that first warm summer day.
AAS suggests growing Sandy in containers and/or the garden, so I'm going to do both to see how it fares. I've already seeded about a 1/2 flat under my grow lights and will try direct seeding it in the garden as soon as the snow disappears (June? July? AGH!)
It's great to see such a strong showing of veggies and herbs winning AAS awards in 2015, including this unique and beautiful summer squash. Bossa Nova boasts exceptional flavour and eating quality, but for me, it's the gorgeous fruits that make this a must-grow.
Each elongated squash has a mottled combination of dark and light green skin, which contrasts nicely against the dark green leaves, making the fruits more visible. No more missed zucchinis hiding beneath the foliage that grow to the size of baseball bats!
Ok, I'm a basil freak. It's my #1 herb and I'm growing about a dozen varieties this year, but Dolce Fresca is the one I'm most excited about.
In growth habit, it's compact, forming a tidy mound that averages about 18 inches tall and 12 inches wide. The plants are quite dense, and attractive enough to be tucked in ornamental beds and containers.
It fills in quickly after each harvest and is also drought tolerant. If you have trouble growing basil, a common complaint among gardeners, consider giving Dolce Fresca a try!
Do you have a favourite All-America Selections award winner?
10 comments:
I love broccoli and this is my first time to grow it from seed. I have a question about basil from seed. Do you have any growing tips? Should I start it now indoors (I'm in zone 5b Ohio) or could I put some seeds in my raised bed?ReplyDelete
I'm looking forward to following your shares as your plants grow this season.Replies
Thanks Bren!! You know I'm a HUGE fan of yours! I'm super excited about this new broccoli.. I think it will really stretch the harvest season. I just started mine this week - April 2nd - and it will go in the garden in about 5 weeks.. assuming the snow actually melts! ha ha.. You can direct seed outdoors, but I find I get much stronger plants when I transplant. If I direct seed, they have to deal with all the challenges of early life outdoors - slugs, dry soil, wet soil, cold temp's, unexpected frost, etc, so it's better to give them a head start under some grow lights or in a sunny window. :)Delete
Really looking forward to seeing how these perform!!! Lettuce Sandy looks awesome!ReplyDeleteReplies
Doesn't it!? :) I will try it in pots and the garden.. assuming the snow melts sometime this year? ha ha..Delete
Just reading your "year round gardening" book. Mostly trying to plan ahead for the fall and next year to extend our seasons at both ends. I do have one raised bed that we have managed to clear the snow off ( we still have 3-4 feet on the ground) It's about 30" x 6 feet I have put plastic on it to speed its thaw. Do I have to wait till it is thawed through or can I seed cold tolerant plants with just the top thawed? ( it is completely off the ground - a "trug". We can get a cold frame made for it this week. We are in northern Ontario about zone 3b? It is still going to -10 to -15 at night but creeping above zero in the day. Next week is supposed to be plus 3-8 most days. Is it too soon, what would you recommend to start?ReplyDeleteReplies
Hi.. great questions!! And I hope you enjoy the book.. you can sow when the snow has gone and the ground is still frozen, but you'll have better germination rates when the soil has thawed.. particularly with cool season veggies like lettuce. I would just leave the plastic cover on a few extra days to hasten thawing.. it's hard to be patient I know, but it will pay off.. Those cold night temp's will delay germination and growth too. We have 3 feet on the garden too.. crazy year! I hope it melts soon, but in the meantime, I'm starting so many seeds under my grow lights.. at least my basement looks like spring! ha ha.Delete
Hi Nikki. Just got your "Year Round Gardening" book and are busy planning for how to implement things to extend our season for the fall and next year. We live in Northern Ontario (zone 3b? ) and are trying to increase the amount of food we can grow for ourselves. I do have one fully raised bed (fully above ground) that we have been able to clear of snow ( still have 3-4 feet on the ground). I have covered with plastic to get it warming up. Temps are hovering just around freezing to +4 in day and about -10 at night. Question. Does the whole bed need to be thawed to seed some cold hardy spring crops or just the top layer? Should I be getting a cold frame top on it or would a tunnel be enough? ThanksReplyDelete
Your post is really wonderful. I can expect more information from this postReplyDelete
I am trying these selections too. Hard to select a favorite. They all look great. The lettuce Sandy has popped up really fast. Also their pepper, Ace. Like you, I'm really excited to try Sandy. It looks great. I hope I'm able to try the new basil - unfortunately the basil mildew has gotten so bad in our area that I didn't get any basil last year. But I'm going to try. I'm also looking forward to Butterscotch, Johnny's new Butternut squash. An a local selection, Parisian Gherkin. My shelves are fuller than usual this year with all these fun new plants! Kathy - Skippy's Vegetable GardenReplyDeleteReplies
Wow Kathy!! I'll be following your posts on Skippy's Vegetable Garden to see how your fare. I'm super excited about Johnny's Seeds new Butterscotch butternut squash too - tiny fruits and compact plants. Ideal for those with smaller spaces. There is NO room left under my grow lights, but I still have about 6 more flats to sow. May have to expand my grow op! ha ha..Delete
Please feel free to leave comments. I welcome your tips, questions, thoughts and ideas (and suggestions for new veggies to grow!)


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Vijay Adiraj is a famous personality on Television, who has been part of many TV serials and reality shows. The TV star has sidelined his acting talents for a while and has taken a liking towards directing movies in big screen. Vijay Adiraj's debut attempt as a director in big screen has resulted in Puthagam. Puthagam is a comic thriller, that attempts to throws light on three youngsters living in Chennai and things that happen in their life with the mix of love, politics and so on.
Here is the plot of Puthagam. Three youngsters live a life with less money to survive. Actors Sathya, brother of actor Arya, Sanjay Bharathi, son of actor Santhana Bharathi and Vignesh have played the three lead roles. Actress Rakul Preet Singh plays the female lead role as a press reporter. She finds romance with Sathya. While the life seems dry without enough money, soon the three youngsters find too much money through an ill way with a connection to a local politician (Suresh). What happens to them forms the rest of the plot.
Puthagam is a slow page turner. The reason is that the director Vijay Adiraj takes his own time to present characters well to the audiences. He almost takes an entire first half of the movie to make the audiences get along with his characters on screen. Some comic sequences and dialogues help the first half a bit.
The second half, however, seems to inject thriller elements, which fails to create what the director intends to create. The screenplay appears dud, as the interesting essence is missing somewhere along the script. The scenes just do not help the movie establish its theme. The climax again turns out in a manner where the hero is portrayed as the one man army to destroy all the evil.
Overall, Puthagam is not a good read for this Pongal holiday!
|: Hot News , Tamil Actress , Tamil Cinema News , Tamil Cinema Reviews
|: Jegapathy Babu , Puthagam Movie Review , ragul Preeth , Tamil Movie Puthagam , Vijay Athiraj


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Have a Question?
Owings Mills Campus
Garrison Hall North, Second Floor
Deciding Students
Bachelor's to Master's Option
A Bachelor's to Master's Option is available for qualified students who are interested in earning both a bachelor's and master's degree. With this option, students may be eligible to save on tuition for up to six graduate courses (18 credits). Students must apply for admission to the Stevenson University Online graduate program and to the Bachelor's to Master's Option during the first semester of their junior year. Admitted students may begin taking graduate-level courses during their junior and senior years. Participating bachelor's and master's degree programs at Stevenson are designed to blend seamlessly, giving students in the Bachelor's to Master's Option a powerful education in a shorter period of time.
Bachelor's to Master's Admission Requirements
- Have and maintain a minimum 3.0 GPA.
- Minimum of 60 completed credits at time of application. Must have completed at least 75 credits to enroll in graduate courses.
- Completed Bachelor's to Master's Application. Please submit these materials to Director of Admission, Amanda Millar (443-334-3334 / email@example.com) in Garrison Hall South - Second Floor.
- Personal Statement
Application deadline for Fall is May 1 and Spring deadline is December 1.
For more information on applying to this program please contact Admissions at 443-334-3334. Note: If you are applying to the Forensic Science and Master of Arts in Teaching programs please contact Ellen Roskes at 443-394-9652 / email@example.com.
The following chart shows which undergraduate majors commonly participate in the Bachelor's to Master's Option. Qualified students in other majors may participate in the Bachelor's to Master's Option with permission from the undergraduate division director or department chair.


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The INT-3D platform has been created at the beginning of 2008 by Dr. Xavier Morelli and Dr. Philippe Roche to answer an increasing demand of the academic laboratories regarding molecular modeling (virtual mutagenesis mainly) and virtual screening (hit finding and hit to lead optimization). Our platform is lodged by the laboratory CRCM in the Institut Paoli-Calmette research campus.
Cancer Research Center of Marseille (CRCM)
Université Aix-Marseille / Institut Paoli Calmettes
27 Boulevard Leï Roure-BP30059
13273 Marseille Cedex 09
The INT-3D platform is dedicated to the "Acceleration of the discovery of new bioactive molecules". The know-how of this platform concerns mainly:
• Molecular Modeling (3D model, structural alignment, virtual mutagenesis…).
• Molecular Dynamics Simulations (free, targeted, steered) and normal mode analyses.
• Management of virtual 2D/3D chemical databases for pharmacological screening.
• Protein-Protein and Protein-Ligand Docking.
• In silico screening (docking, 2D/3D pharmacophore filtering, similarity search)
• Quantitative Structural Analysis Relationship for small molecules (QSAR, CoMFA)
• Hit to Lead Optimization, scaffold hopping.
The antiviral projects represent the main part of the platform activities. We strongly collaborate with many academic research groups in Marseille and in France. We also share several research projects in collaboration with industrial partners.
INT3D is supported by the GIS-IBISA and by the Region PACA
Xavier Morelli (Administrative Director)
Xavier Morelli is "Chargé de Recherche, CR1" CNRS and group leader of the group iSCB group in the CRCM laboratory. He has created the INT-3D platform at the beginning of 2008 and his main interest concerns protein-protein interaction, their specificity and inhibition.
In addition to the administration of the platform, Xavier Morelli is also in charge of the:
• In silico screening protocols
• Docking tools development
• Hit to Lead optimization
+33 (0)184.108.40.206.31 xavier.morellime.com
Philippe Roche (Scientific Director)
Philippe Roche is "Chargé de Recherche, CR1" CNRS. He is in charge of the molecular modeling and dynamics simulations projects in the group ID3 and his main interest concern protein-protein and protein-sugar interactions.
In addition to the general scientific direction of the platform, Philippe Roche is specifically in charge of the:
• Molecular modeling protocols
• Molecular Dynamics Simulations (MD)
• Database management
• Scaffold hopping
+33 (0)18.104.22.168.06 philippe.rocheinserm.fr
1 Integrated Tour dedicated to in silico screening and molecular modeling:
Linux Centos Cluster:
• 32 CPU Intel Xeon running @3,00 Ghz
• 64Go Memory
• 4To-Raid 5-Fiber Chanel-SAS Storage (hard drive)
• 10 Gbytes internal ethernet network
State of the art molecular modeling software:
• Chemo-Informatic: Tripos package (Sybyl, molcad, biopolymer, UNITY, UNITY3D, QSAR, HQSAR, CoMFA, Topomer search, Topomer CoMFA, Volsurf plus, Selector…)
• Docking Protein-Ligand: FlexX (BiosolveIT), OpenEye, Autodock
• Docking Protein-Protein: Haddock, Chemera
• Molecular Dynamics Simulation: CHARMM, NAMD, VMD
• Molecular Visualization & Structure Calculations: pymol, modeller, CNS, ARIA
Quality Control and Label @ INT3D
The 'antiviral activity & projects' of the INT-3D platform has now joined the PCML platform and the Virology Platform of Marseille-La Timone (Dir: X. De Lamballerie) at the beginning of 2009 to create the AD2P platform (Antiviral Drug Discovery Platform, Director: Pr. Jean-Claude Guillemot).
INT3D is now supported by the GIS-IBISA and by the Region PACA
Xavier Morelli (Administrative Director)
Philippe Roche (Scientific Director)
Véronique Hamon (Postdoc)
Marie-jeanne Basse (Technical support)
Bernard Chetrit (IT support)
Betzi S, Restouin A, Opi S, Arold ST, Parrot I, Guerlesquin F, Morelli X, Collette Y. Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein. Proc Natl Acad Sci USA. 2007 Dec 4;104(49):19256-61. Pubmed ID: 18042718
Betzi, S., Suhre, K., Chetrit, B., Guerlesquin, F., Morelli, X. GFscore: A General Non-Linear Consensus Scoring Function for High-Throughput Docking. Journal of Chemical Information and Modeling. 2006 Jul-Aug;46(4):1704-12. Pubmed ID: 16859302
Morelli, X., Rigby, A.C. Acceleration of the Drug Discovery Process: A Combinatorial Approach Using NMR Spectroscopy and Virtual Screening. Current Computer-Aided Drug Discovery. 2007 March;3(1):33-49.
Betzi, S., Guerlesquin, F. and Morelli, X. Protein Protein Interaction Inhibition (2P2I):Less and Less Undruggable Targets. Comb Chem High Throughput Screen 2009 Dec;12(10):968-83. Pubmed ID: 20025563


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State Grassroots Coordinator
State Grassroots Coordinator
As a State Grassroots Coordinator, you will be on the front line to train District Captains to recruit, train and activate new volunteers. You will actively reach out to new District Captains and welcome them into our organization as well as train them to reach out to volunteers to match up their talents with our needs. Responsibilities include...
- Network with our existing District Captains to actively recruit new volunteers.
- Create a team of rapid response District Captains to respond to new volunteers in a timely manner.
- Actively engage District Captains to reach out to volunteers and encourage a deeper involvement within the organization.
- Assist in recruiting District Captains in select areas as delegated by the State Director.
Expected commitment level: 5-10 hours per week
To Apply:
- Step 1: Provide the information below and hit the "Submit application" button.
- Step 2: Complete the 6 question State Grassroots Coordinator survey that follows.
- Step 3: We will be in contact with you shortly.
Your application is not complete until you finish the 6 question survey that follows.


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I'm trying to design my DJ setup and its killing me. I'm no sound guy and the locals in my area are worthless.
My Club will average around 300 people and max out at 700. I'm looking for a simple system with a lot of power. The SQ FT of the room is around 2500 sq ft.I think I can figure out my mixer, laptop, and all of that setup. I'm having a hard time deciding between amps and passive woofers vs active woofers. I see a lot DJs in my area using Cerwin Vega passive woofers. I was searching online and seen good reviews on the QSC KW181 and the JBL PRX618S-XLF Active Woofers. Which direction would you go in? I'm really looking for some serious bass


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The kick-the-can Congress
To understand how far this Congress will go to kick the proverbial can down the road, consider the farm bill — yes, the farm bill.
In the midst of a severe drought, the House Republican leaders are proposing to walk away from farm states and decades of precedent by not calling up the new five-year plan before the current law expires Sept. 30.
Story Continued Below
Whatever its flaws, the bill promises $35 billion in 10-year savings from exactly the type of mandatory spending that Congress promised to tackle in last summer's debt accord. But rather than disrupt its political messaging, the GOP would put it all at risk by delaying action until after the November elections.
There's little institutional memory left in the Capitol — or perspective on the accumulation of cans rolling down the road these days. But the farm bill delay is new ground for any Congress.
Never before in modern times has a farm bill reported from the House Agriculture Committee been so blocked. POLITICO looked back at 50 years of farm bills and found nothing like this. There have been long debates, often torturous negotiations with the Senate and a famous meltdown in 1995 when the House Agriculture Committee couldn't produce a bill. But no House farm bill, once out of committee, has been kept off the floor while its deadline passes.
If pushed into November's lame-duck session, farmers will join Medicare physicians whose pay will be running out, idled workers worried about jobless benefits, and very likely, millions of families faced with expiring tax breaks.
For all the backslapping over the recent transportation bill, that measure expires in just 15 months. The Democratic Senate no longer even tries to do 12-month appropriations bills. Already in mid-July — when the floor used to be humming — the "smart money" is plotting a stop-gap continuing resolution to get to November or beyond.
Such a CR was once treated as a backstop by the Appropriations committees. Now the practice is so prevalent in all areas of government that the letters might stand for "Congress Retreats."
"It's to the point where you almost think you should vote against extensions because they are extensions," Rep. George Miller (D-Calif.) told POLITICO. "If you were looking at the United States from outside, you look and you say, 'What are these people? Fools?'"
Elections do matter, and there's some logic to letting the voters reshuffle the deck before tackling tough issues. But that's not what's happening here.
The presidential campaigns are already being criticized for lacking all substance. But whoever wins, neither President Barack Obama nor Mitt Romney has shown any appetite for this debate — or even knowledge of farm issues.
The Senate has already approved its farm bill; even if Republicans were to win control in November, the GOP's majority will be so narrow that Democrats will be able to block wholesale changes. In the House, the only certainty about a lame duck is there will be even more unhappy people hanging around.


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Although it doesn't look a world different from the later evolutions of the original Koenigsegg CC the new Agera raises the Swedish supercar builder's game to a whole new level.Debuting in production form the Speed Racer liveried R version - complete with ski roof-box - puts out a stunning 1,115hp on biofuel, Koenigsegg reckoning it's on for a Veyron humbling 273mph on a good day. Truly stunning.
Koenigsegg Agera R
Ferrari FF
With the 458 Italia comfortably setting the benchmark by which all other supercars are judged, Ferrari has been given the freedom to do something a bit different. The four-wheel drive, four-seat FF is just that.
A replacement for the 612 Scaglietti, the 660hp FF is a wholly different proposition from its mad shooting brake styling to its all-wheel drive chassis. Luxurious and spacious it may be but it'll still do 0-62mph in 3.7 seconds and 208mph.
Gumpert Tornante
Monstrously fast and mega hardcore, the Gumpert Apollo is a hell of a piece of kit but, let's face it, blessed with a face only its mother could love. For this more mainstream Tornante, Gumpert has wisely enlisted help.
Who better than legendary coachbuilders Touring Superleggera, lightweight pioneers behind classic Astons and Ferraris of old. Thus, Italian style and German engineering combine to spectacular effect, with Gumpert's 700hp brutalism toned back slightly for a (relatively) more relaxed drive.
Pagani Huayra
The Zonda proved former Lamborghini man Horacio Pagani's mastery of carbon fibre as an art form so expectation was high for its replacement, the Huayra. Confusion still reigns about how to pronounce the name though!
Everyone agrees the million-Euro, 700hp, Mercedes-powered Pagani is an absolute stunner, mixing fabulous design with technical trickery - like the four moveable flaps controlling downforce and weight transfer under braking.
Lamborghini Aventador LP700-4
The honest truth? In pictures the Aventador LP700-4 looked like it might be a little too conservative for a flagship Lamborghini. No such worries having seen it!
In the flesh the Aventador is everything a Lambo should be - extravagant, exciting, aggressive and just a teeny bit mad. Given the tech at £200K it seems a relative bargain too!
MTM Audi R8 V10 Biturbo
Chrome wrap? Nope, MTM has actually got the wet and dry out and rubbed this R8's paintwork down to the bare aluminium and polished it for stunning effect. It took them 700 man hours but the result is fabulous.
As is the replacement of the regular 4.2-litre V8 with the 5.0-litre, twin turbo V10 from an Audi RS6. Tuned to 777hp it humbles the 525hp of the standard R8 V10 and unleashes the monster within, capable of 215mph.
Aston Martin Vantage S
The Aston Martin Virage also here at the Geneva Motor Show 2011 is a tasty piece of kit. But the 'baby' Vantage has also come in for attention, and though the changes are relatively detailed, on paper it promises to be an absolute stormer to drive.
There's a new seven-speed automated manual gearbox for starters, this giving a much more aggressive shift and raw feel than a dual-clutch transmission. 10hp extra, a faster steering rack and bulked up bodykit complete the Vantage S package.
Alfa 4C Concept
With all these 1000hp, 200mph-plus megacars around it's nice to see Alfa Romeo reminding everyone that the joy of driving a sports car isn't all about horsepower figures and chest-beating bragging rights.
Promised for production, the 4C will weigh less than 850kg and, as a result, needs nothing more than a 235hp 1750cc turbo engine (a significant number for Alfa fans) for a sub-5.0 seconds 0-62mph time and driving fun to match the stunning looks.
Brabus SLS 700 Biturbo
Brabus had teased with a wide-body styling conversion for the SLS. But we all know the Mercedes tuner is capable of more than that and, sure enough, the engineers have been busy unleashing more power from the 6.2-litre V8.
In the old days Brabus would have bored it out and gone big, but turbos are the way forward now, two of them attached to the V8 for a mighty 700hp and a top speed of 213mph.
GTA Spano
Aiming to put Spain on the supercar map, newcomer GTA faces an uphill struggle making a noise for itself at a show with new cars from Ferrari, Lamborghini, Pagani and others. But the Spano does a good job of standing out from the supercar crowd.
It looks distinctive for a start and features like a glass roof that switches from clear to opaque are neat, ditto the carbon fibre construction and self-built 8.3-litre V10 with a mighty 820hp. GTA claims 0-62 in 2.9 seconds and a 217mph top speed.


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|Our Lady of Good Success
From early childhood, Mother Mariana of Jesus had exercised the secrets of prayer. She was an industrious little bee who daily built her honeycomb with the pollen of her virtues. She loved her relationship with God and found in Him strength for suffering, stimulation for perfection, skill and valor for confronting the forces of evil and, finally, repose and sweetness in the toils of her exile.


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Tuesday, March 6, 2012
The upside down card reader outside my dorm, its magnetic stripe unexpectedly running down the right and not left side. The beep-beep of my door when I hurriedly swiped backward when returning from the shower. My glittery turquoise flip flops, squelching and wet, kicked off into my closet to dry with my yellow bathrobe. The yellow bathrobe I lost when an inebriated girl stumbled into my room nude and needed to be covered up. The Swiffer, wet wipes, dusters, laundry freshener and disinfectant neatly lined in my closet so I could clean my life back into order every time I had a paper to write. Three thousand pages of readings, printed, colour-coordinated and labeled in my transparent plastic drawers. I dropped them in the recycling bin when I finished my thesis. They fell inside with a thud I felt in my stomach and I missed them immediately. The soft pile of my rug which I felt against my face when I laughed so hard I cried and cried so hard I laughed, when there was nothing to do but lie on the floor with my face against the blue. My friend's obnoxious black boots, which I nudged away with my toe while lazing on the floor eating pizza with her, telling her to leave her shoes outside like a good Asian and laughing about how we weren't the clean kind of Asians. The PVTA schedule in my drawer, memorized backwards and forwards (except for the weekend B43 route, with too many stops to keep track of). People on the PVTA. Judging people on the PVTA. That one definitely goes to Hampshire. She is barefoot, not dirty but kind of dusty looking, wearing a shapeless knee length cotton dress and a nose ring. I marvel at how tiny her bones are, how pretty her cheeks and how filthy the soles of her feet from cultivating calluses in preparation for winter. The Amherst guy looks like a stereotype. Popped collar and everything. My red Mount Holyoke sweatshirt, with its Pegasus and class pride that means nothing to anyone but us. My lack of class pride. I am yellow and red, I am orange, I would say, because I am a fake senior, but on convocation I wore only red, unwilling to explain. Feeling fake at J show on senior night and feeling like a double senior while I wrote my thesis and worked three jobs. Walking into my Tuesday job at Ortega House on a Monday night and getting a bright smile from the Latina who thought I was there because I felt at home and not because my body clock was off by 24 hours. Taking naps between classes and forgoing sleep at night because there were too many amazing conversations to be had right outside my door. Amazing conversations, amazing conversations. Saying hey, let's Do Something and registering it as a whole organization over a pizza dinner. Conversations always meant something, except when they didn't. Saying hi, how are you, what can I get you today, would you like that with soy milk, cream cheese on your bagel, should I slice that for you, can I get the little one an orange juice, do you want that in a bag, should I leave space for half and half, no we don't take debit, we're out of Oolong tea and sometimes meeting great people and sometimes not. Cutting my hair and coming in for my shift and having my coworker come very close and look me in the eye and say, you cut your hair, did you? And trying to explain I am actually straight, but I like short hair. Pulling the belt on my black sweater tight around my waist and my gay friend told me I was almost attractive that day, but not usually because I look like the kind of girl a guy would be into and feeling oddly let down. My boyfriend, I would say, my boyfriend is waiting for me to call and thinking about all the girls whose boyfriends weren't a million miles away and wondering what it would be like, what heady freedom would actually mean if I could really use it with a boy I loved. Not really thinking about boys much and realizing how little I missed them, but eventually not realizing at all. The smell of winter-coming, the smell of winter here, the beautiful silence of snowfall. The cookies and kindergarten smell of Kendade-Cleveland-Carr-who knew the difference anyway-the preparing lunch sandwiches for grab and go smell in my 11am class. The boy in my history class-it took me all semester to realize he was a boy, I have never seen a boy so thin-he had a British accent, but he didn't speak much. The professor who always said "Good morning Miss Elahi," enunciating it correctly even though he had seventy two students and he never forgot a name. He said it was okay the day I fell asleep in my seat and actually slid off my chair, because everyone is exhausted sometimes and I clearly was. I excused myself to wash my face and dry it with woody-smelling paper towels and came back and wished I was awake enough to be as inspired as usual. Inspiration, inspiration. I don't remember when it left exactly, but it wasn't long ago. The Stimson room in the library had tea and cookies on Wednesdays at 4pm, but I always remembered too late. The room was full of poetry books and the fireplace was perfect. The feeling of my heart bursting the first time I saw spring, of my jaw dropping when the cherry tree blossomed and scattered pink flowers across the path to where I lived and thinking how ungrateful are these girls who are laughing at my incredulity. YouTube videos on the big screen in Cleveland L2 at night, when we were supposed to be studying biology. I still can't explain how mitosis happens, but the girl I spent the night with was a third culture kid from a dozen different countries and that was altogether more informative. The biology professor had a nice butt and the kind of face you had to imagine with straw hanging out of his mouth-a nice face, but an Anglo-Saxon farm face which asked me too many stupid questions about my culture. All the girls watched his behind and sometimes they noticed Fifi's legs, because she only wore shorts and she had the longest legs of any girl I had seen. She didn't like the professor because he made fun of her town. Towns, outside train windows and wondering what it was like to grow up in a town and be proud of it and caring about it more than other towns. If there was ever a DHA versus Saddar cricket match, I would not care who won, but these kids went nuts at the mention of sporting victories for their suburban homes. Nationalism, my professor scoffed. Ha. Nationalism. Imagined communities. Using those words and taking it for granted everyone would have read the book, or at least the recommended extracts. Coming home and realizing nobody had, but there was so much I had missed learning too. The past is a different country. My two year reunion invitation is in the mail. How far away. How long ago.
3 comments:
- nuclearbattery said...
i didn't want this post to end
- March 06, 2012
- Amna K said...
- March 06, 2012
great as always
made me miss my college. I graduated 3 weeks ago.
- June 16, 2012
Subscribe to: Post Comments (Atom)


text:
Seeing Spots with aussieBum
Lots of cute new underwear coming up at aussieBum. We just got some photos (and a promo video) for their Spot range. Check them out below!
Three color waistbands to choose from (Red, Yellow, Blue) in either a brief or a trunk style. They kind of remind us of 101 Dalmations – but in a "hey, there's a sexy guy in here" kind of way.
What do you think? We didn't mention the best part – the briefs are just over US$15 and the Hipsters just over US$16!
From aussieBum:
This fun, cheeky design from aussieBum is available with bold waistbands and stitching detail in primary colour options of red, blue and yellow. Made from a high quality cotton lycra material for a complimentary fitted look. Spot on for the stylish man!
About aussieBum:
aussieBum is Australia's leading men's underwear and swimwear label. If you doubt yourself, wear something else.
aussieBum is one of the world's most renowned, award-winning swimwear and underwear retail companies. Our products are all made in Australia and sold in over 135 countries across the globe. aussieBum is recognized for the high level of innovation in design and manufacturing plus the cheekiness of the brand itself.
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text:
SURPRISE, Ariz. – No. 1 BYU-Hawaii women's tennis captured its 11th consecutive PacWest title Saturday with a 5-1 victory over Hawaii Pacific at the 2017 PacWest Women's Tennis Championships at Surprise Tennis Complex.
The Sharks (13-5) were able to get the first point of the night as No. 9 Nicole Hoynaski and Oceane Adam topped No. 13 Min (Karen) Liu and Leah Heimuli, but it was all Seasiders (27-0) for the rest of the afternoon. BYU-Hawaii's Michelle Li Sha Khoo and Jeong-Min Jeon topped Leticia dos Santos and Bianca Schuloff 8-3 to tie the match. No. 2 Nannan (Dallas) Zhang and Xin (Summer) Wen then took the 8-0 victory on court one over Lara Meccico and Barbora Kijasova to give the Seasiders the 2-1 advantage heading to singles.
Jeon was the first player to earn a victory in singles topping Schuloff 6-2, 6-2 and Heimuli put BYU-Hawaii within a match of the victory after she won 6-4, 6-2 on court four. No. 2 Liu was the first to earn a set victory in singles with a dominating 6-1 win, but No. 48 Adam jumped out to a 3-0 advantage in the second set. Liu continued to battle tying match at 5 before taking the final two games for the 7-5 win and sealing the match for the Seasiders.
BYU-Hawaii will advance to the NCAA DII Championships May 9-13 at Sanlando Park in Altamonte Springs, Florida. The Seasiders will await its matchup for the tournament at the conclusion of regional play.


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The transition from casually dating someone to being in a fully committed relationship can sometimes be tricky. As your feelings for the person you are dating grow, it is appropriate to change your behavior in the relationship to match your feelings. While there is always a possibility that the guy you are dating will not reciprocate your feelings, showing him that you are interested in being more than just a casual date can bridge the gap between "Just dating" and "In a relationship."
Step 1
Stop planning dates with anyone else. The first step to relationship exclusivity involves sending the image that you are no longer interested in pursuing other men.
Step 2
Remove any questionable photos of you with other men on social media sites or other public venues. While you may just be having a good time with one of your guy friends, publicizing photos of you with other men can give the impression that you are not interested in settling down into a relationship.
Step 3
Spend more time with the guy that you are interested in pursuing a relationship with. He may bring up exclusively dating as a natural response to the increased amount of time that you are spending together.
Step 4
Talk to the guy that you are dating and let him know that you are not seeing other people and are interested in dating him exclusively. By being upfront with him, your date will not have to guess to interpret your intentions.
- Journal of Personal and Social Relationships: Relationship Resources for Coping With Unfulfilled Standards in Dating Relationships: Commitment, Satisfaction, and Closeness
- Journal of Personal and Social Relationships: Consequences of Relationship Status and Quality for Subjective Well-Being
- Journal of Social and Personal Relationships: What is Love? An Empirically-Based Essentialist Account
- Jupiterimages/Photos.com/Getty Images


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Got a 5Ghz lan card in a brand new computer and connected to the 5Ghz network
Sync speed is 75mb down and 20mb up
I used to get about 70/20 on speed tests on my old computer, however on my new PC im only getting 35 down and 3 up
Signal strength is excellent
If I hard wire I do get about 70/20
Solved! Go to Solution.
If you haven't already done it, make sure you turn off "smart setup" on the Homehub.
See link how to do that.
You should also make sure that your card's drivers are the most up to date via the card manufacturer's web site rather than using Windows drivers.
Can't get any drivers to work on Linux, it did come with a CD but i've no CD drive.
I am now trying wired and getting 67/18. My sync speed is 74/20 so shouldn't i theoretically be getting full speed wired ?
If the Network Card came with CD and there are Linux drivers on that you should be able to get them as a download from the card manufacturer.
If not you can get get portable CD drives for about £10 but you may have a driver problem with them due to using Linux.
Ok i already have the drivers on my linux machine.
I heard it is something to do with the full duplex settings ?
Another question, if im hard wired why am i not getting the full speeds ?


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Don't despair that it rarely gets cold enough to freeze lakes and ponds in Mooresville, North Carolina -- just visit one of the nearby ice skating rinks to work on those backwards crossovers. Mooresville, a town about a half-hour north of Charlotte, has several rinks within traveling distance.
Outdoor Rinks
A couple of places nearby have seasonal outdoor rinks, which are especially busy around the holiday season.
The WBT (wbtv.com) Holiday on Ice Outdoor Skating Rink in Charlotte -- 36 miles south of Mooresville -- has 7,000 square feet of ice -- a little less than half the size of an National Hockey League rink. You can bring your own skates and pay only the admission fee, or you can rent skates at the rink. Season passes and group discounts are available.There is some free parking, but not much, so plan to spend a few dollars on that. The rink is also near the NASCAR Hall of Fame. If you're interested in doing a side trip, you can buy a combo ticket for both. Your skating ticket is good all day, so you can take a break and come back later for more.
A smaller outdoor ice skating rink can be found 20 miles south of Mooresville at the Charlotte Motor Speedway in Concord (charlottemotorspeedway.com). The Coca-Cola Family Ice Rink has 5,100 square feet of ice. Besides public skating, it also provides lessons and is available for private events. The price of admission includes skate rentals. It's open seasonally.
Indoor Rinks
The Pineville Ice House in Pineville (pinevilleice.com) has an NHL sized rink -- 200 feet by 85 feet. It's about 45 minutes from Mooresville, and has public skating sessions, figure skating, hockey and private lessons. Synchro skating and hockey at the team level are other possibilities. You can buy snacks at the on-site shop. The rink also has flat-screen TVs, free WiFi and beer and wine available for purchase.
Ice Sports
The Extreme Ice Center (xicenter.com) in Indian Trail is farther away -- closer to an hour. This rink is open year-round; in addition to the standard figure-skating and hockey lessons, it offers broomball and curling. Classes are available for children and adults. Extreme Ice also has a synchronized skating team. If you get hungry, you don't have to eat the pizza microwaved on a paper plate -- the rink has a restaurant with a full-service bar. A fitness center and ballet dance studio are also on-site, as well as a physical therapy department.
Both of the indoor rinks also offer homeschool classes, birthday parties, summer camps and private rink rental. Each also has a pro shop where skaters can buy clothing and gear.
Photo Credits
- Hemera Technologies/AbleStock.com/Getty Images


text: We're not even sure how this is possible, but Shaq tells the WSJ he spends $1,000 a week buying apps. Lately he's been on a big deer hunter games kick, buying ~20 games. He also gives us a break down of his tweets. They're 60% funny, 30% inspirational, and 10% selling you stuff.


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Chrissy Teigen and John Legend have welcomed their second child, a healthy baby boy, People has confirmed.
Teigen announced the news herself on Twitter. "Somebody's herrrrrrre!" she wrote at 1:23 A.M. today—and Legend retweeted it. The couple has not shared any additional birth details yet.
In January, Teigen confirmed on Instagram that she and Legend were expecting a boy after using IVF. "Mama and her baby boy," she captioned her gender reveal shot.
In November, she announced her pregnancy:


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Cat (Feline) Monoclonal MYOD1 Primary Antibody for ICC, IF - ABIN4337151
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Davis, Weintraub, Lassar: Expression of a single transfected cDNA converts fibroblasts to myoblasts. in Cell 1988
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Mouse (Murine) Polyclonal MYOD1 Primary Antibody for WB - ABIN5663747
Ding, Wang, Liu, Li, Zhou, Hu: Characterization and isolation of highly purified porcine satellite cells. in Cell death discovery 2017
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Human Monoclonal MYOD1 Primary Antibody for ELISA, WB - ABIN969305
Mal: Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation. in The EMBO journal 2006
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Human Polyclonal MYOD1 Primary Antibody for IF (cc), IF (p) - ABIN740340
Gong, Zhao, Yang, Li, Chen, Chen, Zhou: The control of mesenchymal stem cell differentiation using dynamically tunable surface microgrooves. in Advanced healthcare materials 2014
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Human Polyclonal MYOD1 Primary Antibody for WB - ABIN6674061
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Human Polyclonal MYOD1 Primary Antibody for WB - ABIN546363
Kitzmann, Vandromme, Schaeffer, Carnac, Labbé, Lamb, Fernandez: cdk1- and cdk2-mediated phosphorylation of MyoD Ser200 in growing C2 myoblasts: role in modulating MyoD half-life and myogenic activity. in Molecular and cellular biology 1999
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Cat (Feline) Monoclonal MYOD1 Primary Antibody for IHC (fro), IF - ABIN531978
Sell, Eckardt, Taube, Tews, Gurgui, Van Echten-Deckert, Eckel: Skeletal muscle insulin resistance induced by adipocyte-conditioned medium: underlying mechanisms and reversibility. in American journal of physiology. Endocrinology and metabolism 2008
Human Monoclonal MYOD1 Primary Antibody for ICC, IF - ABIN2668627
Harada, Ohkawa, Ao, Odawara, Okada, Azuma, Nishiyama, Nakamura, Tachibana: Rat monoclonal antibody specific for MyoD. in Hybridoma (2005) 2010
Human Polyclonal MYOD1 Primary Antibody for IHC - ABIN966632
Reynaud, Leibovitch, Tintignac, Pelpel, Guillier, Leibovitch: Stabilization of MyoD by direct binding to p57(Kip2). in The Journal of biological chemistry 2000
SRF and its cofactor MYOCD likely contribute to the hypertrophy of peripheral airway smooth muscle observed in equine asthmatic airways, while the remodeling of the central airways is more static or involves different transcription factors.
Equine primary fibroblasts were transformed by lentiviral transduction of equine myogenic differentiation 1 into fusion-competent myoblasts.
We address this paradox using basic helix-loop-helix (bHLH) transcription factors ASCL1, ASCL2, and MYOD1, crucial mediators of lineage specification..Although the ASCL factors and MYOD1 have some distinct DNA motif preference, it is not sufficient to explain the extent of the differential binding. All three factors can bind inaccessible chromatin and induce changes in chromatin accessibility and H3K27ac
ACL regulates the net amount of acetyl groups available, leading to alterations in acetylation of H3(K9/14) and H3(K27) at the MYOD locus, thus increasing MYOD expression.
we found that MYOD transcription factor can upregulate miR-223 expression by binding to an E-box region of the gga-miR-223 gene promoter during avian myoblast differentiation. IGF2 and ZEB1 are two target genes of miR-223
A high extent more than 25% of BRAF(V600E) alleles may be associated with disease outcome in PTC patients.
we present the first report of MYOD1 (L122R) mutation in the largest cohort of 49 rhabdomyosarcomas reported so far, that are associated with a relatively aggressive clinical course
Analysis of human rhabdomyosarcoma revealed that MYF5 and MYOD are mutually-exclusively expressed and each is required for sustained tumor growth.
Cell transdifferentiation of primary skin fibroblasts by forced expression of myogenic transcription factor MyoD was performed by quantitative analyses of gene expression and chromatin accessibility profiles.
The results strongly suggest that the combination of MYCL plus MYOD1 may promote direct conversion of human fibroblasts into functional myoblasts that could potentially be used for regenerative therapy for muscle diseases and congenital muscle defects.
Analysis of the chromatin status of Cdkn1c promoter and KvDMR1 in unresponsive compared to responsive cell types showed that their differential responsiveness to the MyoD-dependent induction of the gene does not involve just their methylation status but, rather, the differential H3 lysine 9 dimethylation at KvDMR1.
Data show that MeCP2 promotes gastric cancer (GC) cell proliferation via FOXF1-mediated Wnt5a/beta-Catenin signaling pathway, and suppresses GC cell apoptosis through MYOD1-mediated Caspase-3 signaling pathway.
Our results on Pax7 and MyoD protein expression suggest that proliferation and differentiation of skeletal muscle stem cells are affected in ALS patients, and the myogenic processes cannot overcome the denervation-induced wasting.
The molecular pathogenesis of radiotherapy-induced muscle fibrosis involves the TGF-beta1 pathway and its repression of MyoD expression. Our results suggest a correlation between traditional swallow therapy /neuromuscular electrical stimulation combined therapy and the restoration of TGF-beta1/MyoD homeostasis in cervical muscles.
Unmethylated MYOD1 gene is associated with chemoradiation resistance in Invasive Cervical Carcinoma.
We provide the first description of a human phenotype that appears to result from MYOD1 mutation. The presentation with Lethal fetal akinesia deformation sequence is consistent with a large body of data demonstrating that in the mouse, MyoD is a major controller of precursor cell commitment to the myogenic differentiation programme
these results suggest that sarcoma metastasis can be partially controlled through Pax7/MyoD-dependent activation of miR-182 and provide insight into the role that myogenic transcription factors have in sarcoma progression
The mechanism of bakuchiol-induced myogenesis is described.
These observations demonstrated the first time that Wnt3a can directly activate MyoD expression through targeting cis-elements in the DE and the L fragment.
Studies indicate that MyoD occupies multiple promoters that induce the transcription of genes vital for establishing the myogenic fate and is also implicated as a mediator of many chromatin modifying enzymes for their recruitment to myogenic enhancers.
MUNC is not a classic cis-acting enhancer RNA (e-RNA) acting exclusively by stimulating the neighboring MyoD gene
MyoD acts to promote SC proliferation and transition of cells into differentiation, while myogenin is known to drive terminal differentiation
lncMUMA promoted myogenic differentiation by functioning as a miR-762 sponge to regulate the core myogenic regulator MyoD in vitro. The enforced expression of lncMUMA relieved the decreases in MyoD protein and muscle mass in miR-762 knockin mice
Ablation of the Hes1 oscillator in stem cells interfered with stable MyoD oscillations and led to prolonged periods of sustained MyoD expression, resulting in increased differentiation propensity
MyoD upstream noncoding RNA (MUNC) overexpression in MYOD (-/-) C2C12 cells induces many myogenic transcripts in the complete absence of MyoD protein. Genomewide analysis showed that, while many genes are regulated by MUNC in a MyoD-dependent manner, there is a set of genes that are regulated by MUNC, both upward and downward, independently of MyoD.
By comparative genomic analysis of single nucleotide polymorphism (SNPs) across publicly available data from 17 strains of laboratory mice, the authors show that variant sequences within the MyoD-bound motifs, but not their genome-wide counterparts, are under selection.
Expression patterns of the joint marker Gdf5, tendon and ligament marker Scleraxis, early muscle marker MyoD1, and blood vessel marker Cadherin5 (Cdh5) are presented during the most active phases of embryonic mouse limb patterning.
An absolute requirement for either MyoD or Myf5 in muscle regeneration.
MyoD signaling during myogenesis is regulated by HDAC1.
Linc-RAM regulates expression of myogenic genes by directly binding MyoD, which in turn promotes the assembly of the MyoD-Baf60c-Brg1 complex on the regulatory elements of target genes.
Studies indicate MyoD displays function to regulate determination of skeletal muscle progenitors [Review].
Muscle regulatory transcription factor MyoD regulates the expression of the pro-apoptotic Bcl2 family member PUMA by binding to the promoter region of PUMA. The increase in MyoD binding to the PUMA promoter as a consequence of culture in differentiation media (DM) is diminished in myoblasts silenced for MyoD expression. In myoblasts silenced for MyoD expression, p53 binding to the PUMA promoter is diminished in response
our results indicate that HDAC11 would suppress myoblast differentiation via regulation of MyoD-dependent transcription. These findings suggest that HDAC11 is a novel critical target for controlling myoblast differentiation.
The data showed that Mettl3 is required for MyoD mRNA expression in proliferative myoblasts.
Gm7325, as a novel MyoD-target gene, is specifically induced in activated satellite cells, and may have an important role in skeletal myogenesis.
The ELF-EMFs did not affect C2C12 myoblast viability or proliferation rate. Conversely, at ELF-EMF intensity in the mT range, the myogenic process was accelerated, through increased expression of MyoD, myogenin, and connexin 43
In this study, we identified ubiquitin-specific protease 4 (USP4), one of deubiquitinating enzymes, as a suppressor of MRFs by demonstrating that a knockdown of USP4 enhances myogenesis by controlling MyoD and the level of myogenesis marker proteins in C2C12 cells... we propose that USP4 is a key player in myogenic differentiation; it controls myogenic regulatory factors in a catalytic-independent manner
MyoD regulates the oxidative metabolic capacity of adult skeletal muscle;ChIP-seq analysis identified MyoD binding on the PGC-1b, but not PGC-1a, gene locus;MyoD cooperates with alternative NF-kappaB to regulate PGC-1b transcription; MyoD and RelB co-occupy many other genes involved in aerobic respiration
LSD1 is required for the timely expression of MyoD in limb buds.
bn1 expression is induced during myoblast differentiation, in a p38 MAP kinase- and MyoD- dependent manner. RNAi-mediated depletion of drebrin, or treatment with a chemical drebrin inhibitor, resulted in a similar phenotype in myoblasts: defective differentiation, with low levels of early and late differentiation markers and inefficient production of myofibers.
Data show that MyoD and myogenin associate with distinct chromatin states.
an Enhancer box and a binding site for a cooperative co-activator of MyoD are present in the promoter region of porcine PPARgamma.
Of the eight adult pig tissue types that were tested, the expression of Myf5 and MyoD1 was highest in the muscle tissue.
Single nucleotide polymorphisms in the MYOD1 and GDF8 genes are associated with genetic transcription during myogenesis in pigs.
Therefore, this study demonstrated that the different regulatory adipogenic roles of MSTN in ADSCs and MSCs act by differentially regulating PPARgamma and MyoD expression.
Therefore, the g.489C>T and g.1264C>A SNPs in MYOD1 may be meaningful DNA markers that can be used for improving important porcine economic traits.
The total expression profile of MyoD and Pax7 genes suggests that higher muscularity in Pietrain pigs is associated with the presence of a greater number of active satellite stem cells compared to other breeds.
SKIP might play a role in the regulation of skeletal muscle development in pigs.
Exons and promoters are amplified and sequenced in the 5'UTR region of this gene.
Relative MYOD1 expression was not different, but MYOG expression was higher in the (ligated-tube)crowded group embryos.
MYOD1 intron 1 DdeI polymorphism was not significantly associated with any meat quality traits tested
Transcript abundance for the muscle regulatory gene MYOD1 was lower in animals with more tender beef.
Bos taurus MYF5 activates MYF5 and MYOD1 expression in cultured fibroblasts.
results suggest that MyoD and Myf5 influence the MyHC isoform expression, although the effects are not decisive in specifying the phenotypes of adult muscles
n conclusion, hypoxia stimulates the proliferation of satellite cells and promotes their myogenic differentiation with MyoD playing an important role
Irxl1/Mkx can repress myoD expression through direct binding to its promoter and may thus play a negative regulatory role in muscle differentiation.
Myod in turn up-regulates cdkn1c, thereby providing a positive feedback loop that switches myogenic cells to terminal differentiation
Myf5 and Myod function independently during cranial myogenesis.
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.
myogenic factor 3
, myogenic differentiation 1
, MyoD
, myoblast determination protein 1
, MYOD protein
, myogenic factor MyoD1
, MYOD1 homolog
, myoblast determination protein 1 homolog
, myogenic factor 1
, class C basic helix-loop-helix protein 1
, myf-3
, myogenic regulatory factor
, myogenic differenciation 1, transcription activator
, myogenic differenciation 1
, myoblast determination 1


text:
***Lincoln Football Announcement***
Unfortunately, the heat index today is going to be too high this evening. Lincoln workouts will be cancelled TODAY AND TOMORROW (Thursday and Friday).
Regular preseason practice begins Monday, July 24th from 4-6 P.M. until school starts. We will hand out pads on Monday, but padded practice begins Wednesday.
Saturday's 7 on 7 flag tournament is in the morning (July 29th) at Cocke County High School. Time is TBA (brackets are being finalized).
This will be the last announcement via FB. Any info regarding Lincoln football will now be found on the Remind Me app. If you are not yet in our group, P.M. me to get specifics.
Any Lincoln football practices require a T-shirt, workout shorts, cleats, tennis shoes, and a padded girdle.
We coaches would like to thank the parents for being so supportive and flexible during this summer off season! So many optional football camps and workouts have truly kept our players focused and in shape! We can't wait to begin our 2017 football campaign. We are all in this together, and it just goes to show..... THERE'S NOTHING BETTER THAN BEING A LINCOLN PATRIOT!
Please share/tag!
Lincoln Heights Middle School219 Lincoln AvenueMorristown, TN 37813Phone: (423)581-3200 Fax: (423)585-3763The Hamblen County Department of Education is committed to providing a website that is accessible to the widest possible audience, regardless of technology or ability. This website endeavors to comply with best practices and standards defined by Title II, Section 504 and Section 508 of the U. S. Rehabilitation Act. If you have accessibility concerns, contact our Central Office at (423) 586-7700 ext. 32063 or complete the online grievance form.Disclaimer Regarding PDF Documents, Videos and External Links
Copyright © 2019 Lincoln Heights Middle School


text:
The latest round of tensions between Iran and Saudi Arabia is unsettling what little is left of the Middle East's regional order.
Saudi Arabia's execution of the country's most prominent Shi'ite cleric on January 2nd triggered the apparently state-sanctioned burning of Saudi diplomatic facilities in Tehran and Mershad, a breach of international order that in turn resulted in Saudi Arabia cutting ties with their Persian Gulf neighbor.
Luckily, in the past Saudi Arabia and Iran have demonstrated at least a limited ability to keep their animosity in check.
The countries didn't go to war when an Iranian plot to assassinate the Saudi ambassador to the US at an upscale Washington, DC restaurant was revealed in 2011. It's unclear what if any long-term impact the latest series of incidents will have.
But they're likely to have one lasting effect, a political development that could tangibly shift hte terms of the Middle East's sectarian divide.
On January 4th, Sudan announced that it was also severing diplomatic ties with Iran. This move denied Iran of its sole Sunni Arab ally, undercutting the Tehran regime's argument that Iran's Islamic revolution is capable of transcending sectarianism and uniting the world's Muslims.
More practically, the freeze in relations also closes off the Red Sea port of Port Sudan to Iranian warships and weapons shipments, takes away a staging area for Iran's regional arms pipeline, ends a partnership with a fellow revolutionary Islamist regime, and flummoxes whatever remained of Iran's efforts to win over potential supporters in the Sunni world.
The relationship between Iran and Sudan stems from the National Islamic Front's elevating to power after the 1989 military coup in Khartoum, an event that marked the first instance of a revolutionary Islamist movement taking power in an Arab country.
Over the next decade, Sudan's government sheltered Osama bin Laden, attempted to assassinate the anti-Muslim Brotherhood Egyptian dictator Hosni Mubarak, and tried to impose Islamic law throughout what was then the territorial ly largest country in the African continent.
Even if these measures turned Sudan into an internationally sanctioned rogue state, they created an opportunity for a partnership with a fellow revolutionary regime in Tehran, which had been the world's only revolutionary Islamist government between 1979 and 1989.
The relationship paid off: Iran provided Sudan with weaponry and expertise that allowed the country to set up a fairly extensive domestic arms industry, giving it the capability of building its own automatic weapons, rocket launchers, and even tanks.
The Sudanese regime lost many of it its Islamist trappings. The Islamic Movement changed its name to the National Congress Party (NCP) in the late 1990s and began evolving into a somewhat more conventional dictatorship in hopes of improving the country's economy and relations with the west.
But Sudan maintained close ties with Iran. International isolation over the government's conduct in wars in Darfur and South Sudan gave Sudan the added incentive to deepen ties with a fellow sanctioned regime. Iran and Sudan completed a military cooperation agreement in 2008, while the Sudanese military has deployed Iranian-built drones in both Darfur and the south of the country. The two governments were allies through 2014.
That began to change as the NCP began to faced steep financial crisis — and as Saudi Arabia began mobilizing the Sunni Arab states against Tehran.
The NCP, which is still under international sanctions related to the Sudanese government's human rights abuses in Darfur, had faced a prolonged economic drought after the southern third of the country became the independent state of South Sudan in 2011. Khartoum and South Sudan failed to reach a durable compromise over the post-independence split of South Sudanese oil revenues (the oil's export is dependent on an oil transit infrastructure in the north of Sudan). Oil from the south had previously constituted nearly the entirety of Sudanese government revenue.
At the same time, the Middle East ignited. The escalating conflict in Syria sharpened the region's sectarian divisions, and events like the Yemeni civil war and the thaw in Iran-US relations heightened the competition between Riyadh and Tehran.
These tensions raised made a potentially swing state like Sudan even more important.
As Alberto Fernandez, current Vice President at the Middle East Media Research Institute and the Charge d'Affaires at the US embassy in Khartoum from 2007 to 2009 explained to Business Insider, amid both domestic and regional turmoil the increasingly pragmatic regime in Khartoum began to realize that its survival depended more on Saudi largess than on its relationship with Iran.
"These guys have been in power now for 26 years," Fernandez says of the NCP. "They're no longer the revolutionaries that they were. They're now a regime that wants to hold onto power. And in that sense they were fruit ripe for the plucking by the Saudis."
The thaw culminated in Sudan's March 2015 decision to join the Saudi-led anti-Houthi rebel coalition in Yemen, which is fighting to restore Yemen's internationally recognized government after an Iranian-supported Shi'ite militant movement deposed it in early 2015.
By that point, the NCP had determined that the Saudis had the unrivaled resources and willingness to secure the regime's long-term survival. "The Saudis can still outbid the Iranians," says Fernandez. "The Iranians have technical expertise and other things they can offer, but they're not swimming in cold hard cash the way the Saudis are."
The move has strategic implications for Iran. Sudan's partnership was more than just a symbolic victory for Iran, 0r a sign that the the Islamic Republic's state ideology was capable of resonating with Sunni Arab Islamists too. It also gave Iran a strategic way-point for weapons trafficking into both the Gaza Strip and Central and East Africa.
Sudan was a frequent staging area for Iranian weapons shipments heading north, to Hamas and Palestinian Islamic Jihad in Gaza. Sudan gave the Iranian arms industry, and the Iranian regime, access to regions of strategic and possibly commercial concern. Suspected Israeli attacks targeted Hamas weapons shipments or facilities in Sudan in 2009, 2011, and 2014. And as a 2012 study by Conflict Armaments Research detailed, Iranian munitions have been found throughout Africa, in places spanning from South Sudan to Cote D'Ivoire.
Iran also helped seed a Sudanese domestic weapons industry purported to be the third-largest in Africa, behind only Egypt and South Africa. According to a 2014 Small Arms Survey report, Iran owns a 35% stake in the Yarmouk industrial facility in Khartoum, which is believed to produce artillery, rocket launchers, and military-grade firearms.
Iran's Yamrouk investment hasn't been cost-free for the Sudanese regime: in October of 2012, the Israeli air force attacked the site, likely in order to destroy Iranian-supplied long-range rockets bound for Hamas in the Gaza Strip. Yarmouk was also cited in a 2006 US diplomatic cable published by WikiLeaks for its alleged connection to activities "that have the potential to contribute materially to WMD, missile, or certain other weapons programs in Iran or Syria."
As the Small Arms Survey recounts, Sudanese weapons factories produce a range of armaments, including light weaponry and small rocket launchers of Iranian design. Sudan has flown military drones of Iranian origin, and Patrick Megahan, a research associate for military affairs at the Foundation for Defense of Democracies, noted in an email to Business Insider that Sudan's state weapons enterprises had exhibited "a copy of an Iranian remote weapons station" at an international defense exhibition in Abu Dhabi in early 2015.
Emile Lebrun, the editor of the Small Arms Survey's Human Security Baseline Assessment for Sudan and South Sudan, speculates that Iranian assistance "was already very limited before the Yemen campaign was underway."
But it's still "unclear," he wrote to Business Insider in an email, "whether the Iranian technicians working in the Sudanese arms factories (some hundreds of workers, according to reports) can be replaced with local specialists."
Sudan's value as a strategic asset to Iran, and Iran's role in helping Sudan establish a domestic arms production capability, suggest that the relationship between the two countries may continue in some more muted, sub-official form. There might be some enduring (if informal) cooperation between officials from the two countries regarding weapons trafficking or continued Iranian involvement in the arms sector.
"My sense is that we're going to see Sudan inch away from Iran but Iran will maintain lingering assets in the country whether Sudan likes it or not," says Jonathan Schanzer, vice president of research at the Foundation for Defense of Democracies.
But on the geopolitical level, Saudi Arabia was able to ply away Iran's only Sunni Arab ally — a country that enjoyed longstanding military and strategic ties with Tehran.
"It looks like the Saudis have outmaneuvered the Iranians," Schanzer told Business Insider. "They pulled a proxy out from under Iran's wing."


text:
Thursday, March 13, 2014
Back to the Paris 13 tower
12 comments:
I remember this one, yes.ReplyDelete
There's a building here that they're now in the process of dismantling... and in retrospect, I should have photographed it before the demolition started.
I hope you're there when it comes down, Eric.ReplyDelete
Quel dommage that this is coming down. We have a similar one in NYC (in Queens, actually) called 5 Pointz. Apparently, it's full of asbestos and too dangerous to leave standing. Sad in both cases.ReplyDeleteReplies
Asbestos is a real poison, so yes, no choice...Delete
Like Petrea, I also hope you're there when it (eventually) comes down Eric, but not standing underneath it!ReplyDeleteReplies
LOL. Anything to show you unexpected photos for you guys!Delete
I walked by this building last week, and thought about your October photo, Eric! But couldn't think you would post another one today... ;-)ReplyDeleteReplies
Les grands esprits...Delete
Such an interesting looking building.ReplyDeleteReplies
Yes it is really...Delete


text:
So true – I'm NOT a party animal (anymore – maybe some in my 20's). Went out a little earlier to pick up a few things to nosh on tonight with my husband: the chilled shrimp ring, some French onion chip dip & chips and some fried calamari (fried octopus – sounds gross but is really tasty – husband & I like it!). The boys will be 'out' – youngest probably with his friends, oldest the same with his family – middle son has to work ALL NIGHT as front desk clerk & Night Auditor at his job at the Hilton Hotel. I'm NOT looking forward to that for him – first he's not feeling 100%, has a persistent cough. I can't imagine doing his job tonight, what with all the people who book rooms NOT to stay in like a businessman would, but to have big drinking parties in their rooms – ugh! I talked with oldest (that hotel's Ex. Chef) and ask if he has to work – "No, I'm off until Tuesday!" (that's good – wish his younger brother was, too).
Got a request yesterday to knit (for pay) more boot toppers (for Mommy-to-be's Mother!) – she said she really likes the ones I knit her daughter and would I be able to make her 2 pairs just the same!? I'm not one for liking to do projects for pay – for me, it's too much pressure to make sure they are exactly perfect. Oh well, after much deliberation, I'm done with one of the cream ones and started one of the rust colored ones – just for the variety of knitting different patterns (it gets boring doing 2 of the same thing). I did tell her I'm not exactly sure I have enough rust colored yarn (it was given to me many years ago – not sure if they still make it!). I did find 2 partial balls of it, so am going to attempt to knit them, perhaps making the tops in white – we'll see. Still knitting on the little sage & white scarf – am hoping to finish it by Wednesday so I can turn it in, then it will just be the boot toppers & the pink baby blanket…maybe…knowing me, I 'might' decide to do another scarf, we'll see. (wink)
Mini Eclair Bites
2 C. graham cracker crumbs
1/2 C. powdered sugar
1 1/2 sticks margarine, melted
1 (4 serving size) instant French
vanilla pudding mix
1 1/4 C. milk
2 C. Cool Whip, thawed
3/4 C. premade chocolate frosting
Preheat oven 350 degrees F.
Line 18 mini muffin cups with paper
liners. In medium bowl combine
graham cracker crumbs, sugar & butter;
mix well then evenly press mixture
into bottoms of liners (use your
fingers – press over bottoms & up
sides of liners). Bake 5 minutes
until crust begins to brown – remove
from oven & cool completely.
In medium bowl whisk pudding mix &
milk – fold in thawed Cool Whip.
Place mixture in ziplock bag & snip
off one bottom corner. Fill cups
evenly with pudding mixture.
In small microwave-save bowl heat
frosting 10-15 seconds; stir until
smooth & pourable. Place in small
ziplock bag, snip off one bottom
corner & top pudding mixture with
a dollop of chocolate frosting.
Refrigerate 4 hours until ready to
serve. Makes 18
(recipe: mrfood.com)
Party Shrimp
1 T. olive oil
1 1/2 tsp. brown sugar
1 1/2 tsp. lemon juice
1 clove garlic, thinly sliced
1/2 tsp. paprika
1/2 tsp. Italian seasoning
1/2 tsp. dried basil
1/4 tsp. pepper
1 lb. uncooked large shrimp,
In large ziplock bag combine
first 8 ingredients. Add shrimp;
seal bag & turn to coat.
Refrigerate 2 hours. Drain shrimp,
discard marinade. Place shrimp
on an ungreased cookie sheet.
Broil 4 inches from heat 3-4 minutes
on each side or until shrimp turn
pink. Makes about 2 1/2 dozen
(recipe: tasteofhome.com)
Sesame Chicken Bites
3/4 C. mayonnaise
4 tsp. honey
1 1/2 tsp. Dijon mustard
1/2 C. dry bread crumbs
1/4 C. sesame seeds
2 tsp. minced fresh parsley
1/2 C. mayonnaise
1 tsp. onion powder
1 tsp. ground mustard
1/4 tsp. pepper
1 lb. boneless skinless chicken
breasts, cut into 1 inch cubes
2-4 T. canola oil
In small bowl mix sauce ingredients;
refrigerate until serving
In shallow bowl mix bread crumbs,
sesame seeds & parsley. In another
shallow bowl mix mayonnaise &
seasonings. Dip chicken into
mayo mixture then into crumb
mixture, patting to help coating
adhere to all sides.
In large skillet heat 2 T. oil over
medium-high heat. Add chicken,
in batches, cook until chicken is no
longer pink, turning occasionally
& adding additional oil as needed.
Serve with sauce. Makes about
2 1/2 dozen (with 3/4 C. sauce)
(recipe: tasteofhome.com)
Icy Holiday Punch
(overnight recipe)
1 (6 oz) pkg. cherry jello
3/4 C. sugar
2 C. boiling water
1 (46 oz) can (Dole) canned
100% pineapple juice
6 C. cold water
2 liters ginger ale, chilled
In 4 qt freezer-proof container
dissolve jello & sugar in boiling
water. Stir in pineapple juice &
cold water. Cover & Freeze overnight.
Remove 2 hours before serving.
Place in a punch bowl, stir in ginger
ale just before serving.
Makes 30 servings (about 5 3/4
(recipe: tasteofhome.com)
Almond-Bacon Cheese Crostini
1 French bread baguette (1 lb),
cut into 36 slices
2 C. shredded Monterray Jack
2/3 C. mayonnaise
1/2 C. sliced almonds, toasted
6 strips bacon, cooked/crumbled
1 green onion, chopped
dash salt
(additional toasted almonds,
Preheat oven 400 degrees F.
Place bread slices on ungreased
baking sheet. Bake 8-9 minutes
until lightly browned. In large
bowl combine cheese, mayo.,
almonds, bacon, onion & salt –
spread over bread. Bake 7-8
minutes until cheese is melted.
Sprinkle tops with additional
almonds, if desired. Serve warm.
Makes 3 dozen
(recipe: tasteofhome.com)
7-Layer Mediterranean Dip
1 (8 oz) tub plain hummus
1 (8 oz) C. sour cream
1 (8 oz) jar roasted sweet red
peppers, drained/chopped
1/4 C. crumbled feta cheese
1/4 C. chopped red onion
12 Greek olives, pitted/chopped
2 T. chopped fresh parsley
Baked pita chips for dipping
Spread hummus in 9 inch pie plate;
top with sour cream, red peppers,
cheese, onion & olives. Sprinkle
top with parsley & refrigerate
until serving. Serve with pita chips.
Makes 2 1/2 C.
(recipe: tasteofhome.com)
Hot Reuben Dip
4 oz. cream cheese, softened
1/2 C. Thousand Island salad
1 (8 oz) pkg. (Kraft) Big slice
Swiss cheese slices, chopped
1/4 lb. sliced deli corned beef,
chopped (about 1 Cup)
3/4 C. well-drained sauerkraut
Preheat oven 350 degrees F.
Mix cream cheese & salad
dressing in medium bowl until
blended; add remaining
ingredients & mix well.
Spray bottom of a 9 inch pie
plate with nonstick spray &
spread mixture onto plate.
Bake 20 minutes until heated
through. Serves 20 (2 T. each)
(recipe: kraft recipes)
Cheddar Jalapeno Dip
1 (8 oz) pkg. cream cheese,
1/4 tsp. garlic powder
1/4 C. beer
6 slices bacon, chopped*
1 c. shredded sharp Cheddar
2 fresh jalapeno peppers, halved/
seeded & thinly sliced
Preheat oven 350 degrees F.
Beat cream cheese & garlic powder
in medium bowl using elec. mixer
until blended. Gradually beat in
beer then stir in remaining
ingredients. Spread mixture on
bottom of a 1 1/2 qt casserole
dish or 9 inch pie plate. Bake
15-20 minutes until heated
through. Serves 16 (2 T. each)
*poster recommended using
Oscar Mayer Butcher Thick Cut
Hickory Smoked bacon
(recipe: kraft recipes)
Crockpot Hot Citrus Cider
1/2 gallon apple juice
2 1/4 C. water
1 1/2 C. orange juice
3 (4 inch, ea) cinnamon sticks
1 T. whole cloves
1/4 C. molasses
Garnish: apple slices
Pour all ingredients into crockpot;
mix well. Heat on Low, stirring
occasionally. Keep warm & serve
in mugs with apple slices. Refrigerate
leftovers in covered container up to
3 days. Makes 3 quarts
(recipe: recipesthatcrock.com)
Caramallow Dip
4 C. miniature marshmallows
25 caramels (unwrapped)
1/4 c. canned evaporated milk
Optional 'dippers':
cut up fruit, cubes of angel
food cake, marshmallows,
graham crackers,
Place all ingredients in large
microwaveable bowl. Microwave
on High 2 minutes; stir. Microwave
1 minute until marshmallows are
completely melted & mixture is
well blended. Cool slightly.
Makes 14 (2 T. ea) servings.
(recipe: Kraft recipes)
Our weather has been holding at NICE –
today it was almost 40 degrees F! The
next few days are supposed to get up
to almost 47 – that's amazing for this
time of year in Michigan! (almost makes
you feel like you're waiting for the other
shoe to drop…living here all my life I
KNOW snow is in the forecast sometime
soon – just hope it holds off a little
If you're celebrating the New Year
tonight – have fun, be safe and enjoy
yourselves! (I'll be happy right here
at home)


text:
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Yet the emotions the sight aroused were less about the building itself than about what losing it might mean. Notre Dame is an expression of humanity at its collective best. Nobody could look up into that vaulted ceiling without wondering at the cumulative genius of the thousands of anonymous craftsmen who, over a century and a half, realised a vision so grand in its structural ambition and so delicate in its hand-chiselled detail. Its survival through 850 years of political turbulence—through war, revolution and Nazi occupation—binds the present to the past.
The fire also binds people to each other. The outpouring of emotion it has brought forth is proof that, despite the dark forces of division now abroad, we are all in it together. When nationalism is a rising threat, shared sadness makes borders suddenly irrelevant. When politics is polarised, a love of culture has the power to unite. When extremism divides Muslim from Christian and religious people from atheists, those of all faiths and none are mourning together. An edifice built for the glory of God also represents the unity of the human spirit.