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Are you considering visiting Japan for the first time?
Do you want more than a "typical tourist experience"?
Do you enjoy self-guided travel, yet find Japanese language and logistical issues pose significant challenges?
Adventures in Japan has what you are looking for!
Destinations will include art districts, craft studios, museums, and Japanese art supply houses across Japan from Tokyo to Takamatsu. Learn More Here
Japan is one of the safest, cleanest countries you will ever visit. The people are courteous, the food is amazing, and the culture, with its ancient roots, is fascinating and unique.


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A Brief History of the Marque
Manufrance, St Etienne
Hirondelle 1914-1954
Hirondelle machines were built by Manufacture Francaise d'Armes et Cycles de Saint-Etienne (Manufrance) and often displayed an MF logo.
Established in 1885, Manufrance was France's first mail order company, with an annual catalogue, known as la Manu. It offered a wide range of products, the most famous being guns, bicycles and sewing machines. After WW2, the company introduced cyclemotors and mopeds, with some success.
Hirondelle Models
The 1914 Hirondelle Legere had a 332cc Manufrance SV engine, and was available with sidecar or voiturette remorque (a trailer with seat).
1947 Model B - Ultima 2T 121cc (52 x 57 mm)
1950 125cc 3 speed, 105,000 francs.
Model n°60 of 1953-1954 was a Bernardette scooter type Y52, rebadged.
The 1959 125cc model had an Ydral engine
Sources: BuyVintage.co.uk, Cyclememory.org
Sun Aug 10 2014
speakeasyeslcafe at gmail.com
1948 Hirondelle 125cc
Your advert says its for sale. I would like to know how much is the cost to purchase it. I may also want it shipped to me in Bangkok, Thailand.
Bangkok, Thailand
Tue Mar 18 2014
info at totallybuddha.com
For Sale / A Vendre
Hirondelle 1948 125m3
Barnfind without papers. Was stored for over 35 years. Was running at that time. Engine is not blocked but didn't try to start it.
The frame number is 3293

subset: commoncrawl


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Pokemon Crystal Version - Pok¿mon of the Day: Abra (#63)
|Everybody remembers the good ol' Pokémon of
the Day Guy, right? Well, once Gold and Silver hit the shores of the US
and all the hype had died down a bit, he decided to move to the top of
Mount Kilimanjaro to seek enlightenment. Now that every self-respecting
Pokémaniac has Ruby and Sapphire on the brain, however, it's high
time we revitalize the age-old tradition of bringing you your Pokémon
of the Day! And, as everyone knows, there's only one thing better than
a Pokémon of the Day Guy...a Pokémon of the Day Chick!
Each and every day we'll be taking a close and personal look at one of these unique creatures called Pokémon. Here you'll find all the moves you could ever want (learned, hereditary and all compatible TMs/HMs from G/S/C and R/B/Y, if applicable), breeding chains for hereditary moves, Pokédex entries, general descriptions, max stats, in-game locations, weaknesses and resistances, gameplay tips and one or more suggested movesets (SUGGESTED, people; I'm not telling you what to do) to get the most bang for your Pokébuck.
Today's Pokémon is Abra. Abra has the distinction of being
the first Pokémon you'll find in any alphabetized Pokédex
in addition to being the first step in the widely-respected Alakazam evolutionary
chain. This Psychic family is very versatile and can easily fill any Special-type
niche you might have on your team...no wonder it's almost unanimously considered
the Psychic type of choice amongst those who don't favor legendaries. With
Speed and Special Attack stats that are through the roof and a Defense
stat that's through the...um...floor, Abra and its kin will hit hard and
fast yet shatter like a blown-glass figurine if sent in against the wrong
|NAME: Abra
TYPE: PSI (Psychic)
WEIGHT: 43 lbs.
EVOLUTION: evolves into Kadabra at level 16
AVAILIBLE IN: Red, Blue, Yellow, Gold, Silver, Crystal
LOCATION: Wild Abra are relatively rare in all versions, though they appear in numerous areas. Routes 24 and 25 are your best bet for finding an Abra in Red and Blue, or you can exchange your winnings from the Celedon City Game Corner for one (180 coins in Red, 120 in Blue). Yellow owners can find wild Abra on Routes 5-8 as well as in the Game Corner (this time for 230 coins). Gold and Silver players will meet Abra on Routes 5, 6, 8, 24, 25, 34 and 35 and, once again, can buy one from the Game Corner (though now it's the one in Goldenrod City...200 coins, for those of you who are interested). In Crystal, Abra appears most of the places he did in G/S, though he's migrated from Route 6 to Route 7 and no longer appears on Route 25.
|Learned Moves:
Teleport - Basic
Teleport - Basic
|Compatible TMs:
TM01- Mega Punch
TM05 - Mega Kick
TM06 - Toxic
TM08 - Body Slam
TM09 - Take Down
TM10 - Double-Edge
TM17 - Submission
TM18 - Counter
TM19 - Seismic Toss
TM20 - Rage
TM29 - Psychic
TM30 - Teleport
TM31 - Mimic
TM32 - Double Team
TM33 - Reflect
TM34 - Bide
TM35 - Metronome
TM40 - Skull Bash
TM44 - Rest
TM45 - Thunderwave
TM46 - Psywave
TM49 - Tri Attack
TM50 - Substitute
HM05 - Flash
TM01 - Dynamicpunch
TM02 - Headbutt
TM03 - Curse
TM06 - Toxic
TM07 - Zap Cannon
TM09 - Psych Up
TM10 - Hidden Power
TM11 - Sunny Day
TM13 - Snore
TM17 - Protect
TM18 - Rain Dance
TM20 - Endure
TM21 - Frustration
TM27 - Return
TM29 - Psychic
TM30 - Shadow Ball
TM32 - Double Team
TM33 - Ice Punch
TM34 - Swagger
TM35 - Sleep Talk
TM41 - Thunderpunch
TM42 - Dream Eater
TM44 - Rest
TM45 - Attract
TM46 - Thief
TM48 - Fire Punch
TM50 - Nightmare
HM05 - Flash
|Hereditary Moves (G/S/C only):
Barrier: Breed a female Abra/Kadabra/Alakazam with a male Mr. Mime.
Encore: Breed with a male Mr. Mime.
Light Screen: Breed with a male Electabuzz or Mr. Mime.
Suggested moveset
Talk about versatility...the Abra family can go from all-out offense (such as the moveset seen here) to virtually all defense (considering their ability to learn moves like Reflect, Counter, Thunderwave and Recover), or anywhere in between. Since this is a three-part evolution, I'll have a chance to analyze several different potential movesets and the various roles Abra and its brethren can play on a team. For now I'll go with what has affectionately been dubbed the Elemental Punching Abra (mostly to keep you people from yelling at me for leaving off Recover, since Abra is the only one in its line who can't learn that particular move).
Psychic is a no-brainer. Taking into account Abra's monstrous Special Attack and the 50% extra power STAB affords it, there aren't many Pokémon in the game who won't be severely limping after absorbing a Psychic from Abra. Use it on Poison and Fighting types, naturally, or any of the few types you might encounter against whom none of your punches are super-effective (with the obvious exception of Dark types...using Psychic against one of them would be pretty dumb, considering the fact that it won't hit...*cough*).
There's really no need to explain each of the punches in separate paragraphs; all of them are 100% accurate, a modest 75 base power and work exceptionally well with Abra's incredible Special Attack (can you believe they wasted these beautiful moves on the likes of Hitmonchan in the first three games??). Fire Punch is for Grass types, Ice types, Steel types, and those pesky Bugs that Abra is weak to. Ice Punch will also take care of Grass types in addition to Flying, Ground and Dragon types (kiss your colossal orange butt goodbye, Dragonite!). You'll likely be using Thunderpunch mainly to fend off the plethora of Water types out there, though it's also very effective against Flying types. Of course, messing around with your opponent's stats is always fun, and the elemental punches afford you a one in ten chance of either burning, freezing or paralyzing your opponent.
The King's Rock is an interesting item...in addition to helping Pokémon like Poliwhirl and Slowpoke evolve in new and interesting ways, it grants any Pokémon who carries it into battle the chance to make their opponent flinch with any move in their arsenal (assuming the bearer is faster than their foe, of course). Therefore, it's a great choice for a quick Pokémon with nothing but flat-out attack moves like this particular Abra. Bright Powder and Focus Band are also decent items for Abra to hold, but I hardly ever get a chance to recommend King's Rock so I'm taking advantage of it now.
As you can imagine, this particular Abra won't last long in battle. It's super-effective against darn near everything but its paltry 128 Defense is right out there in the open for all to see and exploit. I'd recommend using this Abra to pick off already-weakened opponents before they have time to react and (hopefully) recalling it before they have a chance to reciprocate. Oh yeah, and this little guy owns the Little Cup in Pokémon Stadium 2. Trust me.
Good luck mastering this sleepy little bundle of kinetic energy, and be sure to check back on Monday for another new Pokémon of the Day!
Please email any questions or comments to firstname.lastname@example.com, or drop me a line if you just wanna say hello! I'm always up for a rousing Pokémon chat. And, as always, feel free to visit us on IGN's dedicated Pokémon Board. See you there!


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The Malibu Award an all-time favorite in crystal awards expresses the exhilaration of riding the wave of success. From its base to the crest the graceful curves in the delicate optical crystal surface are a stunning example of displaying appreciation in a grand manner. This crystal trophy is an expansive dense piece of clear optical crystal that is perfect keepsake for including sand etching.
Production Time: 5-7 Business Days Engraving: Sand Etching Materials: Optical Crystal Artwork Info: Proofs are usually generated within 2-3 business days after placing an order. Nothing is engraved without client approval. Important note: All awards start blank. If you see a specific design you like please advise and discuss with your artist before proof approval.
- Black Premier Box
- Foam Liner
- Ideal for Crystal


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- Lifestyle: Glamour Girl
- Price: $2,500 - $5,000
- Type: Engagement ring
- For a: Woman
- Metal: White Gold
- Stone color: Blue
- Stone cut: Emerald
This award winning bridal ring features diamonds and French cut sapphires in 18k white gold. This unforgettable Beverley K design is available in all metals, mount sizes and various stone options. Price excludes center stone.
From the same designer


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NEMA Research is a Boutique Contract Research Organization that specializes in delivering a range of services that support the needs of the client.
NEMA Research follows a Market Aligned Plan (MAP) whereby we can assist companies from benchtop to bedside.
All projects are processed throughout the entire integrated clinical research network so that comprehensive input can be provided.
We customize our offering of services to the particular project in a time sensitive and cost effective manner. The core of our expertise is in drug development, clinical research implementation, and product support which lead to the generation of accurate, timely, high quality data crucial for our partners' success.
The process begins with a simple phone call to a member of the NEMA Team.


text:
Apidra SoloStar 100 Units/ml, each ml contains 100 Units insulin glulisine (equivalent to 3.49 mg).
Apidra SoloStar 100 Units/ml each pen contains 3 ml of solution for injection, equivalent to 300 Units.
Treatment of adults, adolescents and children, 6 years or older with diabetes mellitus, where treatment with insulin is required.
(Not in-use pens)
Store in a refrigerator (2°C-8°C).
Do not freeze.
Do not put Apidra next to the freezer compartment or a freezer pack.
Keep the pre-filled pen in the outer carton in order to protect from light.
(In use pens)
For storage conditions after first opening of the medicinal product, see section 6.3.
Choose a currency below to display product prices in the selected currency.


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It's official: London is awash with Lady Gaga fever. Fresh from her barn-stomping Roundhouse show opening this year's iTunes festival, the singer has also found the time to astound and delight with her — how shall we put this?— imagination-stretching outfits. Click through to see our top three looks and let us know which mermaid / steam punk / Miss Marple ensemble gets your vote.
Photo: REX USA/Beretta/Sims/Rex.
It's hard to steal focus from those specs, but this intriguing take on modern suiting does the trick.
Photo: REX USA/Beretta/Sims/Rex.
Gaga gives Miss Marple a run for her money in a Vivienne Westwood suit.
Photo: REX USA/Beretta/Sims/Rex.
The Little Mermaid has nothing on this lady. Loving the hot pink lingerie, too.


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Tim Curry did not receive an Oscar nomination for portraying Dr. Frank N. Furter in The Rocky Horror Picture Show.
It is pretty easy to say that Tim Curry is the best part of the film in his feature film debut as Dr. Frank N. Furter a mad scientist transvestite who hails from the planet of transsexual in the galaxy Transylvania. There is not a great deal to Frank N. Furter other than his overt strangeness and the way he things interested in all things sexual, although is also capable of a great deal of violence when brought to it usually in fits of jealousy. Frank N. Furter is the bizarre sexuailzed version of both doctor Frankenstein as well as the monster itself. I suppose there was probably only one way to play the part, and that is the approach Curry takes which is to go head first with his character and to be completely unabashed with his character's style.
This performance is rather in the same vein as Joel Grey's performance as the Master of Ceremonies in Cabaret where it is more about how the performance is performed than what is being performed. Yes there is various strands to this character the lustful transvestite, the evil scientist, the alien with some plan, or just the homicidal maniac, but they don't exactly make a cohesive whole. I am not saying against Curry nor am I really saying anything against the part as this really is the intention of the part. Frank N. Furter is simply there to freak you out well entertain you at the same time, he is not there to create an in depth look at the nature of an evil alien scientist. Frank N. Furter is simply suppose to be strange and entertaining so it is good that Curry's performance is strange and entertaining.
Curry doesn't hold back, that is for sure, playing the part with a devilish glee almost like Frank N. Furter is filled with orgasmic ecstasy simply from talking. This certainly works in creating the sexual creature that is Frank N Furter, and he only adds to that through his delivery of the songs which are done in such a forceful as well as rather slithery fashion. Curry not only fascinates with his style but as well threatens as well. Curry has such strange menace even well he is singing. It is most unusual but Curry pulls it off quite marvelously as being a pure evil but also quite magical in the musical sense. It is an interesting trick and one that Curry pulls off without any visible effort in his outrageous delivery.
Curry jumps around in the styles from a seductive force with his sly smile and piercing eyes, to the mad scientist with a maniacal glee, and to the jealous psychopath with his a ferocious stare. Curry does this all well and is something fascinating to watch every moment he is given something to do. He is just filled with energy and the fact that he is clearly having so much fun does rub off. The only problem with his part really is the fact that sometimes Frank N Furter is forced to just kind of stand there, and that is part of the problem with the film as a whole when it seems to be trying something but takes too long to do anything and ends up going nowhere. To his credit though Curry would be the reason to see the film since whenever he does get the chance to do something he gives it his all and then some.


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Morgan - posted on 10/11/2010 ( 10 moms have responded )
My son is almost 2 years old and he really won't eat anything. He loves his fruits, some veggies, peanut butter and jelly sandwiches, and baby food still. I give him something new and he gags and spits it back out. Can anyone help me please? He use to eat really well and was off baby food and now he won't touch that food again. Any advice would be helpful!
- Helpful (1)
- Nice
- Funny
- Encouraging
- Hugs


text:
Our mission is to build a passion in our community for nature
and the environment through education, experience and action.
Contact Us |
Log In
We've got great programs for campers ages 2 to 15!Click on your age group below for all the details.
The Nest at Earthplace provides all day, safe and reliable care for children aged six weeks to two years of age by trusted professionals in a newly renovated Earthplace space. Learn more.
See first-hand how your efforts can make a difference in protecting and preserving the environment by volunteering at Earthplace! We are looking for volunteers to help clear and line trails, remove invasive plants, weed, rake, spread compost, remove trash, plant native plants, etc. To get involved, email email@example.com.
© Copyright -
10 Woodside Lane
203-557-4400 |
EZ-CMS Content Management SystemBy Build 'N Serv Internet Services


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Engaging, riveting, sad and humorous; demanding the audience to participate both live and while listening to their albums—Slim Cessna's Auto Club has been tagged with every musical description possible. This is fitting, as the group describes their music as American (Is that not what America is, a mixture of everything resulting in something new?); and after more than a decade of working and living as Slim Cessna's Auto Club, they have created their own genre.
Unentitled is another high-water mark in the Auto Club's career. The nine songs here are each thoughtfully crafted with unique arrangements, executed by superb musicianship and fully realized via original, insightful and intelligent lyrics. Tracks like "Three Bloodhounds, Two Shepherds, One Fila Brasileiro" add creepy lyrical imagery to their jaunty choruses. "Do You Know Thee Enemy?" uses Cessna's trademark call-and-response vocals and "Hallelujah Anyway" has Munly serving as an ominous narrator.
Slim Cessna's Auto Club has released a number of critically acclaimed albums on Jello Biafra's Alternative Tentacles label, and Spin Magazine and No Depression have described them as the best live band in America. With two of the most charismatic frontmen around and a tight-knit group of accomplished musicians, Slim Cessna's Auto Club is the past, present and future of American music.


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Rent-to-Own Rentals in Nevada (0)
Welcome to RentalAds.com, where renters, landlords and property managers can either search an assortment of Nevada houses, condos, townhouses, duplexes, apartments and other rent-to-own property rentals, or can promote their properties to rent to potential tenants. RentalAds.com is where both rent-to-own tenants and landlords or property mangers are brought together at a click of a button.
Whether you're new to the state or a current resident looking to relocate to another area, renters literally have thousands of Nevada rent-to-own rentals and lease options so that they can find the exact rental with the precise specifications they're looking for.
Las Vegas is backed by not only a perpetual service industry, which is directly tied to tourism, but a rather strong rent-to-own property market. Based on the annual tourist report for Las Vegas, the average visitor not only stayed for a longer period but spent more in 2012 and 2011 than 2009. Vegas casinos have had their best performances in the past couple of years. In 2012, this trend is expected to not only continue but increase.
Renting Vegas residential property is an investment in a long-term, sustainable and thriving community. There is a steady influx of tourists and new residents that consistently stream into Las Vegas, which provides a consistent number of opportunities in spite of the current state of the economy in the U.S. The success that sustains Nevada as a thriving business and investment venture is not limited exclusively to bright lights, loud casinos, luxurious hotels and wild nightlife. It continues to prove itself as a stable community in which to reside.
Cities like Las Vegas, Nevada was the number one residential market picks on a list of the top ten Best Undervalued Places to Live, which was a comprehensive survey conducted by U.S. News and World Report. Moreover, National Geographic Adventure Magazine deemed Vegas as the most desirable place to live and play in a list of fifty locations. Nevada residents still enjoy no state income tax, low unemployment, clean and safe neighborhoods and spectacular parks and recreation.
From cliff climbing, hiking and mountain biking in the Red Rock National Conservation Area to skiing and snowboarding on the ridge of Mount Charleston, Nevada is a mecca of outdoor events and activities for outdoor enthusiasts. You can also be assured that the local weather will never disappoint, with averages of sunny climate more than three hundred days a year, year round.
RentalAds.com is the quickest and most efficient way renters and landlords can achieve their goals with a user-friendly search tool. This website is simply the most ideal way to promote their rental property. The listings have been posted by owners, landlords and property managers throughout the Nevada area.
Renters have the luxury of advanced search tools that allow them to pick from a list of rent-to-own properties throughout the region, whether in Reno, Las Vegas, Lake Tahoe or Carson City with the exact amenities, features and specifications they're looking for. The bigger the selection, the less time is spent searching and more time living and enjoying what the Silver State has to offer.


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Help Desk Hours
Fall and spring hours *
Monday through Thursday: 8 a.m. to 10 p.m.
Friday: 8 a.m. to 5 p.m. Phone support begins at 9am
Saturday: closed
Sunday: noon to 10 p.m.
* Open limited hours on breaks and closed on holidays
Summer and break hours *
Monday through Thursday: 8 a.m. to 5 p.m.
Friday: 8 a.m. to 5 p.m. Phone support begins at 9am
Saturday: closed
Sunday: closed
* Open limited hours on breaks and closed on holidays
The Help Desk is closed for the following holidays.
- Independence Day
- Labor Day
- Thanksgiving Day
- Day after Thanksgiving
- Christmas Day
- New Year's Day
- Martin Luther King Jr. Day
- Easter
- Memorial Day
The Help Desk is located on the second floor of the University Computing Center.
After hours help desk
An after hours help desk provides support for Bronco NetID, password and Elearning issues when the on campus help desk is closed. Please note that other types of issues will be escalated to the on-campus help desk for resolution during normal business hours. To reach the after hours help desk, call (269) 387-4357 and select option 1.
To report an after-hours campus-wide or system emergency, e.g. Elearning or GoWMU is down, call (269) 387-4357. Appropriate action will be taken in the event of an emergency. Non-emergencies will be handled during normal business hours.
The Technology Help Desk is moving!
April 26, 2018
As of April 30, the walk-in Technology Help Desk will be located, in the same building, at the what was formerly called the UCC lab check-in desk. The move provides quicker and easier access for walk-in customers who need assistance with technology. Checkout the map showing the new location.
Chat-based help is now available!
August 14, 2017
A new "Chat Now!" button has been added the Help Desk contact page. Clicking the button will bring up a chat window where students, faculty and staff can receive instant-message assistance from our Help Desk staff during regular business hours.


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Football coaching made specially for young children
About SoccerDays
Coaching from experience
SoccerDays is a high quality provider of football coaching for pre-school children. Our toddler football classes are located within Essex and East London, the London Boroughs of Havering, Redbridge and Waltham Forest.
Classes take place at School Venues and have been chosen for their excellent gymnasium and sports hall facilities.
Our attitude to go the extra mile and exceed expectations is why our football classes have grown to become so popular with parents and children.
We structure our training programme to be fun and exciting, the games and staff encourage children to build confidence and self esteem at every available opportunity!
Instrumental in achieving such a positive experience for children is to ensure our coaching staff are of the highest calibre.
We recognise the coach is paramount to the success of the business, the ability to interact and engage with young pre-school children requires many individual qualities and skills.
Also our easy to follow football training programme enables children to have fun and participate within a pressure free environment, whilst also giving opportunities for children to improve their physical, personal, social, emotional, communication and language development areas all recommended by the Department of Education Early Years Foundation Stage.
We are proud to achieve such a high standard of coaching and strive to ensure children always enjoy and feel confident within our classes.
Our toddler football classes
Our FA qualified coaches make learning fun and engaging using gameplay techniques specifically designed for toddlers. Making use of their imagination and building on concepts that toddlers understand means they learn super fast – you'll be amazed at their progress.
Toddlers build the foundations of an active and healthy lifestyle and develop confidence. Football really can help give your child an all-round good start in life.
Boys and girls aged 2-7 years are welcome, whether they have played with a football before or not. There's no need to worry about your child enjoying our classes either – we have some fantastic coaches who excel at providing fun and exciting activities, making sure everyone is happy and that every session is a memorable experience.
We guarantee that you'll see the benefits from the very first session – every week your child will be excited and eagerly awaiting their next SoccerDays class!
I have been impressed with the SoccerDays organisation. The programmes are fun and well structured. The staff are brilliant with the children – SoccerDays has a reputation for employing excellent staff.Colin Reid


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Power Play
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You must be logged into Bookshare to access this title. Learn about membership options, or view our freely available titles.
- Synopsis
- It is the year 2018—a highly volatile nuclear world. Israel has obliterated the deep underground nuclear weapons facility built by Iran. The United States has destroyed the nuclear facility of a defiant North Korea. Against this background, the Russians have upped the stakes in the latest world power-play—cyber warfare—to reduce the United States to helplessness: a three-strike missile attack on the National Security Agency at Fort Mead, Maryland, while simultaneously jamming the top-secret electronic access key to America's nuclear launch system—the nuclear football. If successful, Russia would blow the United States off the nuclear map. Meanwhile the British Royal Navy, formerly the most powerful in the world, is rapidly crumbling, leaving the United States without its main deep sea ally at a time when they're needed most. As this geo-political battle comes to light behind close doors dealings and dark secrets, it is up to Mossad spymaster, codenamed the 'Golan,' to avert the Russian scheme, and there is only one man he in turn can trust to get the job done: US Navy Seal Mack Bedford. It is now up to Mack Bedford, the hero previously encountered in The Delta Solution , Intercept , and Diamondhead , to devise a plan to stop the Russians before they and their cyber weaponry reach the Chinese border—the launch site of their master plan. And with the entire country's fate in his hands, Mack and his hard-trained, one of a kind SEAL Team 10 must not, cannot fail.
- Copyright:
- 2012
Book Details
- Book Quality:
- Publisher Quality
- 9781593157326
- Publisher:
- Vanguard Press
- Date of Addition:
- 09/24/12
- Copyrighted By:
- Patrick Robinson
- Adult content:
- No
- Language:
- English
- Has Image Descriptions:
- No
- Categories:
- Military, Literature and Fiction, Mystery and Thrillers
- Submitted By:
- Bookshare Staff
- Usage Restrictions:
- This is a copyrighted book.


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Enjoy these Free Stickers.
This printable is a basic themed starter kit for your planner.
For more Planner Sticker options please check out my
Budget Friendly Printable
Etsy Shop.
Large Planner Boxes measure 1.5x1.9
Small Boxes measure 1.5x1"
Large Washi Tape is designed to be cut down to your planning preference.
With some creativity this set can be used on multiple planner designs.
I do not own the Graphic Images. The illustration credit belongs to their rightful owner.
Anyone can make these stickers using Google search.
Reminder all of my printables on my Blog are FREE for your printing pleasure.
All I ask of you is, please send your friends over my way, please do not share the actual file.
To download your free printable CLICK HERE.
You will be redirected to a PDF download.
These are NOT cut FILES.If you would like to convert your PDF file into a JPEG
there are free websites that offer this service such as THIS one.
Print as many times as you want on Plain Printer Paper, Sticker Paper or Large Shipping Labels.
Personal Use Only. Not to be redistributed for resale or part of a giveaway.


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Enter the YouTube ID of each video separated by a semi-colon (;). Example: "LV5_xj_yuhs; QgaTQ5-XfMM; VWW8DMpfI9U; BgAlQuqzl8o;"
NTSB is investigating the March 23, 2018 crash of a 2017 Tesla Model X electric passenger vehicle on U.S. 101 in Mountain View, Santa Clara County, California.
4/12/2018 - Tesla Party Removal Notification Letter to CEO Elon Musk
Contact: NTSB Media Relations
Phone Number
(202) 314-6100


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San Francisco College Counseling & Tutoring:
Ages 4-12 Academic Enrichment, study skills, Talent Search Test Prep for High Achievers (pre-K-6th graders):
I accept young students for private tutoring sessions throughout the year. Parents in the San Francisco Bay Area: please email or call to discuss your child's needs and desires and we can schedule a first session if it seems likely your student and I will form a good learning partnership.
7th/8th grade SSAT/HSPT/Lowell Test/ISEE:
I am accepting highly motivated, high-achieving students who want to attend best-fit high schools in the San Francisco Bay Area or excellent Boarding Schools throughout the USA and around the world.
7th graders: This is the PERFECT year for ambitious students to begin study for TOP SSAT scores and readiness to excel in the most rigorous and exciting College Prep High School Programs.
8th Graders: Improve GPA & increase SSAT/ISEE/HSPT/Lowell scores & Prep for High School success all at the same time — Start NOW on an intensive program.
8th and 9th graders:
Schedule a two-hour consultation now to map out YOUR route to less stress, greater enjoyment of your High School years, and many rewarding successes as you prepare for your best GPA, SAT/ACT scores, and mix of rewarding activities that ensure you gain admission to a college you love.
HS Sophomores and Juniors College Counseling and/or Test Prep, intensive full-service options:
Those who want to register for one of the few available spots for Full Service College Counseling or Full Service College Counseling + Test Prep should call ASAP. Only 2 spaces left for juniors and only 4 spaces remain for sophomores.
Students may begin private test prep lessons any time, as this test is offered year-round. Those who wish help with Graduate School applications may make appointments before your application process begins, usually in Mid February for Fall enrollment. If you seek help with applications to Graduate programs which continue to accept applications into February or March, email or call today.
Writing of all levels, AP/SAT II exams in French, Spanish, US History:
Call or email to discuss ways I can help you reach your highest goals in one-to-one partnerships for enrichment and expansion of all you do in school and via small group work with ambitious peers.
I will continue to accept students of all ages for private lessons aimed at surpassing individual goals. I look forward to a school year filled with exciting challenges in which I continue to learn and grow along with all my clients.


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Salero's Glazed Pork Belly Is a Gleefully Fatty Sandwich
The new West Loop spot has a 1/2-inch thick slab of uncured pork belly, and it's good for every bite.
Price point: $14 for the glazed pork belly sandwich
While bacon enjoys nearly universal approval, devouring a 1/2-inch thick slab of uncured pork belly still divides us. It's sort of like Kanye at an awards show: Either you think he's an ungrateful brat hogging the spotlight, or the only exciting presence at a staid and completely superfluous ceremony. Salero's (621 W Randolph St, 312-466-1000; salerochicago.com) opinion on the matter is made absolutely clear with the glazed pork belly sandwich.
At first glance, the sandwich looks like a BLT variation, but this glistening slab of pork is far too greedy to share the spotlight. Instead, it completely dominates each bite, with a crispy exterior and an ultra juicy interior. Obviously, the rest of the components play more of a supporting role, but that doesn't stop them from making an impression. The creamy hazelnut romesco sauce accentuates the richness of the pork, while the pickles go in the other direction, adding crunch and acid.
Instead of fries, Salero serves the sandwich with a heap of papas bravas. They certainly look beautiful all coated in the sauce, but the potatoes probably would have been a bit crunchier had they come out naked with the spicy tomato sauce on the side. But that's a minor quibble on an otherwise gleefully fatty lunch.
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Have you heard? I'm back internet dating!
I know I swore off internet dating a while ago - too many freaks, too many £££, but I was recommended a London based site that I have to say is coming through with the gays. After being on there for a week I already have two dates set up AND they're with relatively normal looking people.
However I decided to go on a practice date this weekend before I started dating anyone half decent. I know harsh, but welcome to the world of internet dating - it's really cutting. And transparent. I sent a message to a guy the other night, referencing something from his "About Me" blurb - made it funny - and I can now see that he has read that message, checked out my profile and not messaged me back. I'm sorry, I'm hardly a munter and at least answer an engaging question that I sieved out from your fucking dull profile.
I may be coming at this the wrong way.
So anyway, a guy messaged me out of the blue and I decided he would be my warm up before the real invitations started flooding in - not really my type, his hair looked like he had taken styling tips from Peter Andre circa 1995, but I thought what harm could a coffee date in Soho on a Saturday afternoon with a Myst-e-rious Girl do?
I walked in and The Practice Date was sitting alone at the end of a long communal bench. Let me tell you, girlfriend needs to update his profile pic because he was hot. Long gone was the Peter Andre look-a-like hairstyle and in it's place was a salt and pepper do that would out Clooney, Clooney.
We sat down and right out of the gate we were chatting about everything from gay rights in Russia to when did we think Betty White from the Golden Girls was going to die. It was one of those great first dates that you hoped would never end.
OK a few stats: he is Indian - I know, I'm a Pilau Rice Queen (that's it, I promise), he is a doctor, he lives in Hampstead, he is a doctor, he is originally from Wales, but has lost the accent, he is a doctor, he prefers riding a bicycle to a car, he is a doctor, he prefers dogs to cats and he is a doctor.
So we finish coffee and walked out into the early spring sun for a stroll around a bustling Soho. As we walked we invaded each others personal space with gentle arm grazes and nudges. We even stood gazing into each others eyes as I teetered on a curb, achingly close to a kiss, giggling at the moment. It was so fucking cute, I felt like I was in a British rom-com called Notting Actually.
After a few blocks lost in conversation not realising we had been going round in circles, I could see him looking at his phone. He had eluded to the fact he had plans later and I asked if he needed to go and meet those plans. He said yes and then asked if I wanted to join him for a drink with his friends. I hesitated initially and then agreed to one. So off we went, almost skipping, down Old Compton street.
I have to say his friends were a bit of debbie downer and I couldn't wait to get away. So after one drink I made my excuses and left, but not before I told my Practice Date that I had a great time and made a plan for the coming week to meet and perhaps have dinner. We both agreed on a day and then gave him a peck and a cuddle and off I went.
I floated down to Leicester Square and then onto the tube, my mind racing, replaying every moment, every glance. I made mental preparations to introduce him to my friends and family. I even thought about what colour Sari I would wear when we tied the knot in a lavish four day Bollywood style wedding on the beaches of Goa with my entire back catalogue of Kylie CDs as a dowry.
I may have skipped ahead.
So on Monday morning he messaged me asking if we could move Thursday to Saturday. Oh and also if it would be OK if we could be just friends.
Erm buried the lead!
WHAAATT? Friends? I just bought a home henna kit!
But seriously how does that date equate to a "just be friends" message? And no we cannot move Thursday to Saturday because there isn't going to be a Thursday at all! I have enough friends, what I don't have is enough boyfriends. And that's exactly what I said back to him. He didn't reply.
Maybe I was his practice date.


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text:
Joe Finch
For over forty years I have earned my living making pottery. I owe this success to many people who have helped me over the years but especially my father who not only gave me an excellent training but has continued to be a source of knowledge and inspiration.
My pottery is intended for everyday use: dishes, bowls, jugs and plates, pots for cooking and serving food. Practical, unassuming, wood-fired stoneware ceramics that I hope are both desirable and affordable. All my pots are 'thrown' on the wheel and most are decorated with slips before being raw-glazed and fired once in my large wood fired kiln, where the random effects of the wood ash makes each pot individual.
Joe makes pots for every day use: dishes, bowls, jugs and plates, pots for cooking and serving food, vases for flowers. Practical, unassuming, stoneware ceramics. His pots are 'raw-glazed' then 'once fired' in a large wood burning kiln that he designed and built himself. Recently he has built a second chamber to the kiln and is 'soda firing' in it.


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Local plan
NSP: Additional information
You can find out more information about the different parts of the New Southwark Plan previously consulted on, including their supporting documents, below.
New and Amended preferred option policies consultation
Following previous rounds of consultation (see below for more information) the council consulted on a set of new and amended policies for the preferred option stage of the New Southwark Plan between June to September 2017. This 'interim' consultation set out:
- new and amended planning policies including a social regeneration policy, new housing policies (including affordable housing), business and employment policies and car parking policies
- new and amended site allocations
- a new area vision for Crystal Palace and Gipsy Hill
New Southwark Plan: New and amended preferred option policies (pdf, 3.8mb)
You can view and download the supporting documents below:
- Cabinet report (pdf, 180kb)
- Integrated impact assessment, including equalities impact assessment and health impact assessment (pdf, 449kb)
- Consultation plan (pdf, 256kb)
- Consultation report on the New Southwark Plan consultation so far (pdf, 300kb)
- Habitats regulations assessment (pdf, 108kb)
Area visions and site allocations preferred option consultation
We consulted on an initial set of area visions and site allocations (pdf, 15.6mb) between February to July 2017. You can view and download the supporting documents to the draft Area Visions and Site Allocations below, and view and download the cabinet report under item 13 on this page.
- Site Allocations methodology paper (pdf, 153kb)
- Integrated Impact Assessment, including the health impact assessment and equalities impact assessment (pdf, 1.4mb)
- Consultation Plan (pdf, 76kb)
- Consultation report on comments on sites and visions received during the preferred option consultation on the policies of the New Southwark Plan (pdf, 953kb)
- Habitats Regulations Assessment (pdf, 169kb)
Area visions
Area Visions provide the strategic vision for the future of Southwark's distinct places and neighbourhoods. They set out key infrastructure enhancements, opportunities for public realm and transport improvements and growth opportunities for new homes and jobs. Area Visions also identify the prevailing character of different places to be renewed, retained or enhanced. Development proposals should be formulated in the context of the relevant Area Vision and should demonstrate how they contribute towards realising the strategic vision for that area.
As part of this draft of the plan, we consulted on Area Visions for:
- Bankside and The Borough
- Bermondsey
- Blackfriars Road
- Camberwell
- Dulwich
- East Dulwich
- Elephant and Castle
- Herne Hill and North Dulwich
- London Bridge
- Nunhead
- Old Kent Road
- Peckham
- Rotherhithe
- Walworth
Following this consultation, we consulted on a new Area Vision for Crystal Palace and Gipsy Hill as part of the "new and amended policies" consultation (see above).
Note on Old Kent Road Area Vision
The detailed Area Vision for the Old Kent Road is being prepared separately through an Area Action Plan (AAP). The Area Vision contained in this consultation is based on the vision and detailed proposals presented in the AAP Preferred Option Version which was consulted on from June to November 2016. The council will consider all consultation responses which were received in this previous stage of consultation in preparing an updated vision.
Site allocations
Site Allocations are planning policies which apply to key potential development sites. Site Allocations set out the land uses that must be provided as part of any redevelopment, alongside other acceptable land uses that may be provided in addition to the required land uses. For example, Site Allocations may specify that development must provide new public open space, new public access routes, and new health or education facilities.
New Southwark Plan preferred option policies consultation
We consulted on the preferred option draft of the policies in the New Southwark Plan between October 2015 and February 2016. You can find the draft policies document (pdf, 1.7mb) here and the supporting appendices and documents below. You can find the cabinet report agreeing to go out for consultation on the plan here.
New developments proposed in the borough need to meet the requirements set out in our planning policies. This needs to be demonstrated in the various documents submitted as part of a planning application. The council makes a decision on whether to approve or refuse planning permission for the new development. This decision is informed by whether the proposed development meets the requirements set out in our planning policies.
Our studies and documents used to support our policies and plans can be found in the evidence base section.
You can find supporting appendices for the preferred option version of the New Southwark Plan below:
- NSP PO Appendix 1 Southwark Council strategies/link to related NSP policies consultation v1 (pdf, 59kb)
- NSP PO Appendix 2 Town centre boundaries consultation version (pdf, 1.5mb)
- NSP PO Appendix 3 Protected shopping frontages consultation version (pdf, 8.3mb)
- NSP PO Appendix 4 New open spaces consultation version (pdf, 2.2mb)
- NSP PO Appendix 5 SINCs consultation version (pdf, 2.3mb)
- NSP PO Appendix 6 Cycle and car parking standards consultation version (pdf, 147kb)
- NSP PO Appendix 7 Plan monitoring targets consultation version (pdf, 99kb)
- NSP PO Appendix 8 part 1 APZs class I consultation version (pdf, 9.8mb)
- NSP PO Appendix 8 part 2 APZs class II consultation version part 1 of 3 (pdf, 9.7mb)
- NSP PO Appendix 8 part 2 APZs class II consultation version part 2 of 3 (pdf, 9.1mb)
- NSP PO Appendix 8 part 2 APZs class II consultation version part 3 of 3 (pdf, 3.3mb)
- NSP PO glossary for consultation (pdf, 70kb)
- Policy comparison table FINAL V2 (pdf, 116kb)
- Southwark vision areas bubble map Jan 2016-1 (pdf, 240kb)
Supporting documents for the policies of the preferred option version
You can find supporting documents for the preferred option version of the New Southwark Plan below:
- NSP options consultation report (pdf, 1.2mb)
- NSP preferred option consultation plan (pdf, 127kb)
- Integrated impact assessment New Southwark Plan PO and appendix (pdf, 195kb)
- NSP PO IIA appendix 2 part 1 of 2-1 (pdf, 2.1mb)
- NSP PO IIA appendix 2 part 2 of 2 (pdf, 2.2mb)
- NSP PO IIA appendix 3 (pdf, 400kb)
- Draft validations checklist assessments list (pdf, 54kb)
Sign up to MySouthwark and opt in to receive planning policy consultation updates on your profile, including on the New Southwark Plan and the Old Kent Road.
Page last updated: 08 October 2019


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« ForrigeFortsett »
pleted, they set sail homewards; and though the ships were dispersed by violent storms, they all arrived safely in different ports of England. The queen and the persons engaged in this adventure were delighted to find " that the matter of the gold ore had appearance and made show of great riches and profit, and that the hope of the passage to Cathaia by this last voyage greatly increased." The queen gave the name of Meta Incognita to the newly discovered country, on which it was resolved to establish a colony. For this purpose a fleet of fifteen ships was got ready, and 100 persons appointed to form the settlement, and remain there the whole year, keeping with them three of the ships: the other twelve were to bring back cargoes of gold ore. Frobisher was appointed admiral in general of the expedition, and on taking leave received from the queen a gold chain as a mark of her approbation of his past conduct. The fleet sailed on the 31st of May, 1578, and in three weeks discovered Friezeland, of which possession was formally taken, and then held its course direct to Frobisher's Straits. The voyage hitherto had been prosperous, but distresses and vexations of every kind thwarted the attempt to fix a colony. Violent storms dispersed the fleet; drift-ice choked up the
strait; one small bark, on board of which was the wooden
house intended for the settlers, was crushed by the icebergs and instantly went down; thick fogs, heavy snow, with tides and currents of extraordinary violence, bewildered the mariners, and involved them in endless distresses. At length, after enduring extreme hardships, it was resolved to return, and postpone to the ensuing year the attempt to make a settlement in the country. The storms which had frustrated the object of the expedition pursued the fleet in its passage homeward: the ships were scattered, but arrived at the various ports of England before the commencement of October." The Busse of Bridgewater, in her homeward passage, fell in with a large island to the south-east of Frieze* Hakluyt, vol. iii.
land, in latitude 5739, which had never before been discovered; and sailed three days along the coast, the land appearing to be fertile, full of wood, and a fine champagne country. On this authority the island was laid down in our charts, but was never afterwards seen, and certainly does not exist; though a bank has recently been sounded upon, which has revived the opinion that the Friezeland of Zeno and the land seen by the Busse of Bridgewater were one and the same island, which has been since swallowed up by an earthquake.*
Success seems to have deserted Frobisher after his first voyage, which alone indeed had discovery for its object. When the sanguine expectations to which he had given birth were disappointed, his voyages were looked upon as a total failure; and he appears himself, for a time, to have fallen into neglect. But in 1585 he served with sir Francis Drake in the West Indies; three years later he commanded one of the largest ships of the fleet which defeated the Spanish armada; and his gallant conduct on that trying occasion procured him the honour of knighthood.
Frobisher's zeal in the pursuit of north-western discoveries is supposed to have been fostered by the writings of sir Humphrey Gilbert, a gentleman of brilliant talents and romantic temper. When we contemplate the early discoveries of the Spaniards and Portuguese, we see needy adventurers, and men of desperate character and fortune, pursuing gain or licentiousness with violence and bloodshed. But the English navigators, who, in the reign of Elizabeth, sought to extend our knowledge of the globe, were men of a different stamp, and driven forward by motives of a more honourable nature. They undertook the most difficult navigations through seas perpetually agitated by storms and encumbered with ice, in vessels of the most frail construction and of small burden; they encountered all the difficulties and distresses of a rigorous climate, and, in most cases, with a very distant or with no prospect of ultimate pecuniary advantage. Sir Humphrey Gilbert was one
* Barrow's Chron. Hist. p. 94.
of those gallant spirits who engaged in the career of discovery chiefly from the love of fame and thirst of achievement. In 1578 he obtained a patent, authorising him to undertake western discoveries, and to possess lands unsettled by Christian princes or their subjects. The grant in the patent was made perpetual, but was at the same time declared void unless acted upon within six years. In compliance with this condition sir Humphrey prepared, in 1583, to take possession of the northern parts of America and Newfoundland. In the same year queen Elizabeth conferred on his younger brother, Adrian Gilbert, the privilege of making discoveries of a passage to China and the Moluccas, by the north-westward, north-eastward, or northward; directing the company, of which he was the head, to be incorporated by the name of "The colleagues of the fellowship for the discovery of the north-west passage." The fleet of sir Humphrey consisted of five ships, of different burthens, from 10 to 200 tons, in which were embarked about 260 men, including shipwrights, masons, Smiths, and carpenters, besides "mineral men and refiners;" and for the amusement of the crew, " and allurement of the savages, they were provided of
music in good variety, not omitting the least toyes, as .
morrice dancers, hobby horses, and Maylike conceits, to delight the savage people, whom they intended to win by all fair means possible." This little fleet reached Newfoundland on the 30th of July. It is noticed, that at this early period, "the Portugals and French chiefly have a notable trade of fishing on the Newfoundland bank, where there are sometimes more than a hundred sail of ships." On entering St. John's, possession was taken in the queen's name of the harbour and 200 leagues every way; parcels of land were granted out; but the attention of the general was chiefly directed to the discovery of the precious metals. The colony being thus apparently established, sir
Humphrey Gilbert embarked in his small frigate, the Squirrel, which was, in fact, a miserable bark of ten tons; and, taking with him two other ships, proceeded on a voyage of discovery to the southward. One of these vessels, the Delight, was soon after wrecked among the shoals near Sable Island; and of above 100 men on board, only twelve escaped. Among those who perished were the historian and the mineralogist of the expedition; a circumstance which preyed upon the mind of sir Humphrey, whose ardent temper fondly cherished the hope of fame and of inestimable riches. He now determined to return to England; but as his little frigate, as she is called, appeared wholly unfit to proceed on such a voyage, he was entreated not to venture in her, but to take his passage in the Golden Hinde. To these solicitations the gallant knight replied, "I will not forsake my little company going homeward, with whom I have passed so many storms and perils." When the two vessels had passed the Azores, sir Humphrey's frigate was observed to be nearly overwhelmed by a great sea; she recovered, however, the stroke of the waves; and immediately afterwards the general was observed, by those in the Hinde, sitting abaft with a book in his hand, and calling out, "Courage, my lads! we are as near heaven by sea as by land." The same night this little bark, and all within her, were swallowed up in the sea, and never more heard of. Such was the unfortunate end of the brave sir Humphrey Gilbert, who may be regarded as the father of the western colonisation, and who was one of the chief ornaments of the most chivalrous age of English history."
* Hakluyt, vol. iii.
voy AGES of John DAVIS. – RESULT OF HIS RESEARCHES. HE BELIEVES IN THE ExistENCE OF A NORTH-WEST PASSAGE. - NorthERN ExPEDITIONS OF THE DUTCH. - VOYAGEs of WILLIAM BARENTz. – cortNELISON PASSES THE STRAIT of WAIGATz. - BARENTZ REACHES THE NORTHERN EXTREMPTY of Nov.A. Z.E.M.B.L.A. - DESCRIPTION OF THE WALRU.S. — SEconID Voy A.G.E OF BARENTZ. - infortMation Received froxi THE SAMoy EDs. – THIRD Vox AGE.- SPITZ BERGEN AND CHERRY ISLAND DISCOVERED. — BARENTZ AND HIS CREW WINTER, in Nov.A. Zevi Bla. - THEIR surfert INGs. - Extraortoin ARY REFRACTION. —DEATH OF BARENTZ, AND voy AGE OF THE crew IN open BoATs. - ATTEMPTs or THE DANEs. To ExPLORE GREENLAND. - Vox AG es or JAMEs HALL. — FATE or HALL AND or KNIGHT. - HENRY Hu Dson. - HE MAKEs obSERVATIONS ON THE DIP OF THE NEEDLE. - HIS VOYAGE Tow ARDS THE POLE. – SECOND voyag E. – PLACE of THE MAGNETIC POLE.-A MERMAID DESCRIBED.- Thir D Voyag E. – Discovers HUDson's River. — FourTH voyage. — sails To THE west. — ENTERs HUDson's BAY. — NARRATIve of HIS PROCEEDING. - MUTINY OF THE CREW. – H UDson AND THE SICK MEN TURNED ADRIFT. —- RETURN of The MUTINEERS.
THE zeal and ability exerted by Frobisher in the cause of north-western discovery was foiled, as we have seen, by the vain pursuit of the precious metals. The ill success of the recent voyages restored speculation to its legitimate pursuit; and it was now resolved to despatch an expedition of which discovery should be the sole object. The merchants of London, being satisfied " of the likelihood of the discovery of the north-west passage," fitted out two small barks, the one of fifty, the other of thirty-five tons, which they entrusted to the command of John Davis, an expert and courageous seaman. He sailed from Dartmouth on the 7th of June, 1585, and by the middle of July was on the western side of Greenland, where the coast presented such a bleak and


text:
Well, I was able to sleep in a bit this morning thank goodness. Because tomorrow the adventure really begins. We had a small breakfast at the hotel and then headed for Greeneville. It was a nice drive and as we got close you could see the snow covered Great Smoky Mountains with clouds nestled among the peaks. It was a very pleasant site.
Years ago, when I first applied to work for the National Park Service, I could apply to two parks. I put in for Mesa Verde and the Great Smoky Mountains. I was actually contacted by both parks but Mesa Verde came first and I moved to Colorado. While I never became a permanent Ranger, my time at Mesa Verde is what brought me back to Colorado. I had met my future wife Tracey while working at the Santa Monica Mountains in California. I fell in love and proposed and then convinced her to move to Colorado. I love living in the Mountains. But sometimes I wonder what life would have been like if I had gone to the Great Smoky Mountains instead?
After checking in to the Quality Inn, we went out to find some food and drove through Historic Greeneville. Today, I got my first glimpse into the town where my father was born and live during his childhood. He grew up as a Sharecropping Farmer and moved around quite a bit between Florida and Greene Co. Tennessee. However, Historic Downtown Greeneville on a Sunday is a very desolate place and we ended up getting some food on the main highway nearby.
But I am looking forward to exploring the multitude of historical markers, monuments and buildings around here. My Uncle Ross will be arriving tomorrow and we can make some plans for the week to see the many places of their youth. While many of the buildings are now gone, it will still be great to see the locations and imagine of a time long past.
Tonight I was able to meet Hayley Stills for the first time. We have emailed and talked on the phone for the past five years and it was great to see her in person. We spent a few hours reviewing what we knew of the Stills line and of William Henry Stills, the progenitor of all the Stills in this area. William is something of an enigma, we know of his time in Greeneville but we only have hints of his time in South Carolina and Virginia. Whispers from old Census records and stories passed down through generations. We know not who his parents are. Our conversation concluded with the idea that the science of a new generation, Y-DNA testing may be our only fruitful path forward. Hayley and I will meet up again a few more times this week to track down stories from old generations and hunt for ghosts in Kelley's Gap. Named for our Ancestor John Kelly.
John is supposedly from Ireland and a recent DNA test of my father reveals that my dad is 23% Irish and this supports that believe. His origin story goes something like this.
John Kelley, Sr. came from Armagh, Ireland about 1771 and landed in North Carolina on the captain's pretense of having lost his bearings, some say because of the slave trade. Apparently, so the story goes, their vessel drifted so far south that the heat was intense, and they were thirteen weeks in reaching their destination and then only because, after fourteen days in such heat that the ship's chains would sizzle as they touched the water, they persuaded the captain with the rather forcible argument that they would throw him overboard if he didn't change his course. John landed on the North Carolina coast, taught school, and finally married Anna Hunter, by whom he became the father of three children: John, Joseph, and Andrew. He crossed the mountains at Kelley's Gap, and settled in Greene county, where some of his descendents still live, and hold as a relic his old chest brought from his native land.
Hayley and I will visit Kelley's gap and we hope to meet up with a Kelley relative to hear the stories in person.
But tomorrow morning belongs to TnBreeze, Cemetery Hunters Extraordinaire who post their accomplishments on Findagrave. Like Hayley, we have corresponded over the years. I brought my boots just for them and we will be hunting ghosts, thankfully my cousins, Brian and Tammy Clouse, know just where to look.
Pleasant Dreams.


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Manitoba NDP leadership: Greg Selinger re-elected, remains premier
Pallister, Oswald react to Premier Selinger's leadership win; caucus revolt led to race for top spot
The votes are in and Greg Selinger remains the leader of the Manitoba NDP and the province's premier.
It was a tight race, but Selinger beat out former minister of infrastructure and transportation Steve Ashton and former health minister Theresa Oswald, scooping up 759 of a possible 1,490 votes in the second round of voting Sunday.
ON MOBILE? CBC reporters' Twitter election coverage
BLOG: Tears, cheers show uniting warring factions of Manitoba NDP no easy task
A total of 1,699 NDP delegate votes were cast in the morning in a first ballot that saw Ashton squeezed out of the race with 502 votes. That total number of votes dipped by about 209 in the second round, meaning that many Ashton supporters abstained from the final vote.
Oswald, Pallister react
In the end, Theresa Oswald netted 726 votes but it wasn't enough to oust Selinger.
"I think that when you stand up for what you believe in, and you try your best, even if you don't win in the end, then it's not for nothing ... It's for everything," Oswald said, who added that she still has hope that the party will win the next provincial election.
"I would have loved to have been on the other side in that decision, without question."
Manitoba Progressive Conservative leader Brian Pallister said the fact that New Democrats voted Selinger back into power reflects poorly on the party.
"There's a saying, I think something like: 'the more things change, the more they stay the same,'" said Pallister. "Nothing's changed here. I think Manitobans want change. I think the NDP proved today that they aren't going to get change from the NDP."
Selinger, who refused to step down and continued to govern during the NDP leadership campaign, ran a confident if not tepid campaign, juggling his daily duties as premier the entire time.
This was a historical race by many measures. It has never happened before in Manitoba where a sitting premier was openly challenged by someone within their party and a leadership race ensued.
"Our party is stronger now, we've got more members, our finances are in decent shape, we've focused ourselves ... we've got one of the strongest economies in the country," Selinger told media in Winnipeg following the decision.
"When you can get results for the people of Manitoba, you always earn the chance of [serving them again]."
How did we get here?
Selinger called for a leadership vote last fall after a caucus revolt saw five cabinet ministers resign. Oswald was among the infamous five rebel ex-ministers who went public with concerns over Selinger's ability to lead the party to victory in the 2016 provincial election.
The revolt stemmed from Selinger's public approval ratings tanking in the polls after the provincial government pushed through a PST increase of one per cent in 2013. That revolt, and the increase to an eight per cent provincial sales tax, ultimately precipitated the leadership election that would see Selinger retake the party helm.
What's next for Selinger?
Moving forward, Selinger will be flanked by the new president of the party Ovide Mercredi, the NDP's first aboriginal president.
Mercredi, a former Assembly of First Nations chief, was strongly endorsed by Selinger and ended up ousting incumbent Ellen Olfert and beat out 18-year-old NDP provincial council member Tyler Duncan for the position Saturday.
On the PST increase, Selinger's stance hasn't really wavered. The PST currently rakes in about $280 million for the province annually.
I believe we came out of this with a greater desire to serve the public.- Manitoba Premier Greg Selinger
He has committed to using the tax revenue created from the increase to fund a $5.5-billion plan that would focus on flood mitigation, road and bridge repair.
"The sales tax was a government decision, and Greg has repeatedly stated that he takes responsibility for the way in which it was introduced to Manitobans," Selinger's spokesperson told CBC News last week.
"It was a decision made following significant flood events and the need for a broader economic recovery plan. The sales tax has added much needed revenue to improve flood protection and address bridge and road infrastructure. And the overall economic plan has resulted in growth, protected services and job creation. The province's economic growth will be the best in the country over the next two years."
New childcare spaces
Selinger's 2014 budget guaranteed an increase of 5,000 new childcare spaces would be created. He has also claimed that under his watch the party would do away with interest on post-secondary university loans.
Selinger will also be expected to set a completion date for the spring 2015 budget, something that is normally handed down in early April. Selinger had said that the budget release was being postponed in light of news that the federal budget release date had been pushed back.
The re-elected leader made very few policy announcements on the campaign trail. And on Sunday, he declined to comment on what his first moves as premier would be going forward, but did say reconciling party divisions was on his radar.
"We all support those values; our profound respect and commitment to human rights. I know we all support those things as New Democrats, and I believe we're even more committed to that now that we've gone through this process," said Selinger.
"I believe we came out of this with a greater desire ... to serve the public."
With files from the Canadian Press


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News overview
Simulo is now available for free download
Jun 11, 2019
Quentin Leirens
Nicolas Luyckx
We are pleased to announce that Simulo, our clinical trial simulator, can now be downloaded for FREE (yes, you did read it correctly!).
Especially for PAGE, a new version of Simulo has just been released.
And the icing on the cake, this version now includes features that were exclusively reserved to the Expert version.
It is FREE, no training is required and you activate your license yourself in a few seconds.
SGS Exprimo delegation at PAGE 2019
Jun 11, 2019
Quentin Leirens
Nicolas Luyckx
Elodie Valade
Ingrid Michon
SGS Exprimo will be present at the PAGE conference, 11-14 June in Stockholm. Come visit our booth to learn more about our consulting services. We will also demonstrate the Simulo software for clinical trial and dosing simulations.
Announcement Simulo workshop at ACoP
May 31, 2019
Quentin Leirens
Nicolas Luyckx
SGS Exprimo will run a one-day hands-on Simulo workshop on performingclinical trial simulations on 19th October 2019 at the ACoP conference.
Presentation of Simulo at PhUSE US Connect 2019
Mar 01, 2019
Quentin Leirens
Nicolas Luyckx
Nicolas Luyckx and Quentin Leirens gave a lecture about Simulo software, clinical trial simulation & optimization at the biometrics PhUSE confrence in Baltimore, 24th-27th February.
Announcement PBPK workshop in Berlin
Nov 23, 2018
SGS Exprimo and the FU Berlin will run a two-days hands-on PK-Sim® & MoBi® workshop on introducing PBPK for human dose projection and drug-drug interaction (DDI) prediction on 21st-22nd Feb 2019 at the Institute of Pharmacy, FU-Berlin, Germany.
Simulation course at KULeuven 2018
Jun 06, 2018
In collaboration with Exprimo, the Katholieke Universiteit of Leuven is organizing a 2-day simulation course on 9th and 10th of July.
Meet the team at PAGE 2018
May 31, 2018
Quentin Leirens
Nicolas Luyckx
A delegation of SGS Exprimo is present at the PAGE conference in Montreux with several posters.
Come visit our booth to learn more about our consulting services. We will also demonstrate new features on Simulo software for clinical trial and dosing simulations.
Pharmacokinetic-pharmacodynamic modelling of neutrophil response to G-CSF in healthy subjects and patients with chemotherapy-induced neutropenia
Mar 02, 2018
Philippe Jacqmin
Isabelle Delor
A paper where SGS Exprimo was heavily involved has been recently published in the British Journal of Clinical Pharmacology. Simulo was very useful to evaluate if the PKPD model reproduced adequately nadir values, time to nadir and time to recovery from neutropenia for subjects on chemotherapy.
Comparative assessment of pharmacokinetics, and pharmacodynamics between RTXM83™, a rituximab biosimilar, and rituximab in diffuse large B-cell lymphoma patients: a population PK model approach
Feb 15, 2018
In silico evaluation of pharmacokinetic optimization for antimitogram-based clinical trials
Feb 04, 2018
Through collaboration with the university of Lyon, Simulo was intensively used to simulate and optimize antimitogram-based clinical trials. The result is an impressive simulation-based paper published in the journal for American Association for Cancer Research.
Two-day Clinical Trial Simulation course at PAGE 2018
Jan 12, 2018
Quentin Leirens
In the context of the next PAGE meeting, SGS Exprimo is running a two-day Clinical Trial Simulation course on Monday and Tuesday 28-29 May.
Best wishes for 2018
Dec 20, 2017
SGS Exprimo wishes you all the best in 2018!
Clinical Trial Simulation course at University of Lyon
Nov 20, 2017
Ruben Faelens from SGS Exprimo teached a 4-hour session at the Master Pharmacology, Modeling and Clinical trials (PHAME) at the University Claude Bernard Lyon 1, using Simulo!
Simulo – A User-Friendly Platform for Advanced Trial Simulations. A Case Study in Oncology.
Oct 26, 2017
Quentin Leirens
In the context of ACoP, Belén presented a poster about a case study in oncology implemented in Simulo, our clinical trial simulator.
How can modeling and simulation improve the clinical trial go/no-go decision-making process, accelerating drug development?
Oct 23, 2017
Per Olsson Gisleskog
Following the Modelling and Simulation Webinar presented by Per Olsson and Alberto Russu (Janssen), a white paper entitled "Clinical Trial Simulation: An Efficient Tool for Improved Study Designs, Dose Selection, and Go/No-Go Investment Decisions" has been written.
How can Modelling and Simulation Fuel the Clinical Development of Biosimilars?
Oct 03, 2017
After gaining an extensive experience in biosimilar projects, Bernardo and Daniel discuss, within an article in the Journal of Clinical Studies, why Modelling and Simulation have an important role in the Clinical Development of Biosimilars.
SGS Exprimo delegation at ACoP 2017
Sep 28, 2017
Per Olsson Gisleskog
SGS Exprimo will be present at the American Conference on Pharmacometrics, 15-18 October in Fort Lauderdale. Come visit our booth to learn more about our consulting services. We will also demonstrate the Simulo software for clinical trial and dosing simulations.
Andreas Lindauer at the annual conference of the German Pharmaceutical Society in Saarbrücken
Sep 28, 2017
Our Senior Consultant, Andreas Lindauer, is giving a talk at the annual conference of the German Pharmaceutical Society in Saarbrücken entitled: From Mouse to Man – Translational Modelling in Immuno-Oncology.
Public Clinical Trial Simulation course in collaboration with Freie Universität Berlin
Sep 22, 2017
Quentin Leirens
Per Olsson Gisleskog
SGS Exprimo is running a public two-day Clinical Trial Simulation course on Thursday and Friday 2-3 November in Germany, together with Professor Charlotte Kloft's team at Freie Universität Berlin.
SGS Exprimo welcomes Merran Macpherson on board
Sep 08, 2017
We are pleased to announce that Merran starts with Exprimo on the 11th of September 2017.
Nicolas Luyckx joins Exprimo
Sep 05, 2017
We are delighted to announce that Nicolas Luyckx joins the Exprimo team, effective 11 September 2017.
Tobias Kanacher has joined Exprimo!
Aug 31, 2017
We are pleased to welcome Tobias Kanacher to the Exprimo team of consultants.
SGS Exprimo is now extending services to also include physiologically based pharmacokinetic modelling and simulation, PBPK M&S
Jul 11, 2017
The use of PBPK is expected to continue growing in all phases of drug development. During drug discovery the approach is utilized in the screening of compounds.
Modeling & Simulation Webinar
Jul 07, 2017
Per Olsson Gisleskog
Clinical Trial Simulations: An Efficient Tool for Improved Study Designs, Dose Selection and Go/No-go Investment Decisions, by Per Olsson and Alberto Russu.
Europe: Tuesday 19/09 at 3pm CEST.
US: Thursday 28/09 at 9am CDT.
Importing parameter estimates in Simulo: a video tutorial
Jul 05, 2017
We created a video tutorial, showing you how to import parameter estimates from Nonmem into Simulo.
Defining a model in Simulo: video tutorial
Jul 05, 2017
We created a video tutorial, showing you how to implement a basic model in Simulo.
Defining the trial protocol in Simulo: video tutorial
Jul 05, 2017
Philippe Jacqmin
We created a video tutorial, showing you how to define the trial protocol in Simulo
Can early phase ECG assessment serve as an alternative for thorough QT studies? A review of the literature
Jul 04, 2017
Thorough QT (TQT)-studies are recommended according to the 2005 ICH E14 guidelines to assess the potential of novel drugs to prolong QT interval. These stand-alone studies are expensive due to the large amount of subjects and typically carried out in Later Phase drug development. Replacing TQTstudies by incorporating QT-effect measurements in Early Phase SAD/MAD trials with an Exposure-Response (ER) QT-analysis could be an alternative enhancing cost-efficiency.
SGS Exprimo is sponsoring the DDMoRe Model Repository Challenge and works on a PharmML SO importer embedded in Simulo
Jun 19, 2017
SGS Exprimo decided to support the DDMoRe Model Repository Challenge and, consequently, to promote model sharing.
Two-day Clinical Trial Simulation course at PAGE 2017
Jun 05, 2017
Quentin Leirens
Per Olsson Gisleskog
In the context of the PAGE meeting, SGS Exprimo ran a two-day satellite course on Monday and Tuesday 5-6 June.
Angela Äbelö joining !
May 24, 2017
We are delighted to welcome Angela Äbelö to our team of consultants. She will start at SGS Exprimo on June 1.
How can modelling and simulation optimize the clinical development of adalimumab biosimilar candidates?
May 18, 2017
Quentin Leirens
Per Olsson Gisleskog
In the context of the 7th European Biosimilars Congress, held in Munich 15-16 May 2017, Bernardo de Miguel Lillo presented an abstract and a poster about how we optimized the clinical development of an Adalimumab biosimilar candidate thanks to modelling and simulation.
Population Pharmacokinetic and Pharmacodynamic Modeling of Etelcalcetide in Patients with Chronic Kidney Disease and Secondary Hyperparathyroidism Receiving Hemodialysis
May 15, 2017
Per Olsson Gisleskog
Same Stats, Different Graphs
May 03, 2017
Justin Matejka and George Fitzmaurice show a convincing example of the value of data visualization. In this short paper, the authors transform the "Datasaurus" dataset into 12 different datasets, all with the same mean and standard deviation.
This makes a very convincing argument to present more than only summary statistics, and it is an entertaining read as well!
Top selling pharma drugs in 2016
Apr 28, 2017
PharmaCompass provided an interesting overview of the top selling drugs in 2016. Abbvie's Humira generated record sales of US $16.078 billion in 2016, followed by Gilead's Harvoni (US $9.081 billion) and Amgen/Pfizer's Enbrel (US $8.875 billion).
Time-to-Seizure Modeling of Lacosamide Used in Monotherapy in Patients with Newly Diagnosed Epilepsy
Apr 04, 2017
Baseline disease severity was the most important predictor of seizure probability. Simulations suggest that an initial target dose >200 mg/day could potentially benefit patients with greater disease severity.
TDM Example in R Shiny
Mar 25, 2017
In this article, we demonstrate a TDM approach for dosing beta-lactams.
Simulo training for KULeuven
Mar 24, 2017
Quentin Leirens
Professors Pieter Annaert and Thomas Bouillon from the KULeuven (Belgium) attended a Simulo training session.
PK-Sim and Mobi now opensource
Mar 24, 2017
The PK-Sim and MoBi software suite, originally developed by Bayer Technology Services, has now become open-source under GPLv2.
SGS Early Phase Drug Development Course, 9 May 2017, Antwerp
Mar 13, 2017
On May 9th 2017, SGS Life Sciences is organizing a course in early phase drug development for clinical team members of start-ups and interested academics.
Next to regulatory and clinical protocol consultancy, SGS Exprimo will present PK/PD M&S methods to optimize drug development.
ISO9001:2015 certification for Exprimo datacenter
Mar 10, 2017
IT is considered a 'key risk area' for R&D Consultancy companies like SGS Exprimo. Our datacenter vendor has now achieved ISO9001:2015 compliance, further proving the quality Exprimo provides to its clients in all areas of project execution.
Simulo in the media
Mar 08, 2017
Several media outlets are writing about Simulo!
How can modelling and simulation optimize the clinical development of biosimilars?
Mar 01, 2017
Bernardo de Miguel Lillo explores the competitive advantages SGS Exprimo can offer in the development of biosimilars
Simulo Press Release
Feb 23, 2017
SGS Exprimo officially launches Simulo platform to provide modeling and simulation solutions for clinical trial design optimization.
Population pharmacokinetics of ticagrelor and AR-C124910XX in patients with prior myocardial infarction.
Jan 30, 2017
Simulo: technical information
Jan 27, 2017
Simulo is complex software. In this article, we explore how it was developed.
The Simulo Expert library: an overview
Jan 27, 2017
Philippe Jacqmin
Simulo Expert is delivered with a wide library of demonstration models. Explore them in this article.
Enrica and Belén on board
Jan 17, 2017
SGS Exprimo is pleased to welcome Enrica Mezzalana and Belén Valenzuela in its team of consultants.
Evidence of NI-0101 pharmacological activity, an anti-TLR4 antibody, in a randomized phase 1 dose escalation study in healthy volunteers receiving LPS.
Jan 01, 2017
Philippe Jacqmin
Using Model-Based "Learn and Confirm" to Reveal the Pharmacokinetics-Pharmacodynamics Relationship of Pembrolizumab in the KEYNOTE-001 Trial
Jan 01, 2017
Population Pharmacokinetic/Pharmacodynamic Modeling of Tumor Size Dynamics in Pembrolizumab-Treated Advanced Melanoma
Jan 01, 2017
Simulo training at University of Lyon
Dec 13, 2016
To support the University of Lyon (prof. Michel Tod) in their research efforts wrt cancer treatment optimization, SGS Exprimo provided a 1-day webinar training in Simulo.
Simulo training at University of Navarra
Dec 01, 2016
SGS Exprimo gave a course about "Simulo" at the research group of prof. Iñaki F. Trocóniz at the University of Navarra. At the end of the two days, all 10 attendees were confident to use Simulo in subsequent research and teaching activities.
How modeling and simulation (M&S) supported the development of the immuno-oncology drug pembrolizumab
Nov 25, 2016
During his time at Merck (MSD) our consultant Andreas Lindauer participated in the modeling and simulation team that worked on numerous model-informed approaches to support the development of pembrolizumab (KEYTRUDA), a new monoclonal antibody approved for the treatment of melanoma and other cancer types. Check out a series of recently published articles by this M&S team.
Clinical Trial Simulation training at University of Lyon
Nov 24, 2016
In collaboration with the University of Lyon, we presented a 2-hour session in Clinical Trial Simulation. This session fitted nicely within the Master's program curated by Emilie Henin (Calvagone).
The 10 students managed to explore the PK model for Sunitinib. 4 students struck gold at the end, managing to create an efficient design that proved biosimilarity.
An abstract for Simulo
Nov 23, 2016
Quentin Leirens
Per Olsson Gisleskog
Simulo – a platform for advanced model based simulations using R
Exposure-response analyses supporting ticagrelor dosing recommendation in patients with prior myocardial infarction.
Nov 18, 2016
Trip to PKUK 2016
Nov 11, 2016
Per Olsson Gisleskog
Per Olsson Gisleskog and Daniel Röshammar went recently to PKUK conference in London (9th to 11th November). They summarize their trip with a selection of presentations.
SGS BioPharm Day 2016
Oct 25, 2016
SGS hosted a scientific seminar on clinical trial solutions. Ruben Faelens from Exprimo was present to talk about model-informed adaptive trials in Phase 1.
Olaparib does not cause clinically relevant QT/QTc interval prolongation in patients with advanced solid tumours: results from two phase I studies.
Oct 01, 2016
Predicting the effects of combining broadly neutralizing antibodies (bNabs) binding to different HIV viral epitopes
Sep 06, 2016
Per Olsson Gisleskog
Clinical pharmacology profile of an oral selective androgen receptor down-regulator, AZD3514: Implications on the design of ongoing castrateresistant prostate cancer clinical studies
Sep 02, 2016
Population Pharmacokinetics and Pharmacodynamics of the Calcimimetic Etelcalcetide in Chronic Kidney Disease and Secondary Hyperparathyroidism Receiving Hemodialysis.
Sep 02, 2016
Per Olsson Gisleskog
Ordered mesoporous silica to enhance the bioavailability of poorly water-soluble drugs: Proof of concept in man
Aug 20, 2016
Characterisation of Population Pharmacokinetics and Endogenous Follicle-Stimulating Hormone (FSH) Levels After Multiple Dosing of a Recombinant Human FSH (FE 999049) in Healthy Women.
Jun 01, 2016
Population exposure-response modeling of oral nepadutant administration in infants with colic.
Jun 01, 2016
Evidence of Different Propofol Pharmacokinetics under Short and Prolonged Infusion Times in Rabbits
Jun 01, 2016
Population Pharmacokinetic Modelling of FE 999049, a Recombinant Human Follicle-Stimulating Hormone, in Healthy Women After Single Ascending Doses.
Jun 01, 2016
Systems Pharmacology Modeling of Prostate-Specific Antigen in Patients With Prostate Cancer Treated With an Androgen Receptor Antagonist and Down-Regulator
May 01, 2016
Phase Ib/II study of elisidepsin in metastatic or advanced gastroesophageal cancer (IMAGE trial)
Apr 01, 2016
Use of an integrated modelling and simulation approach to develop a simplified peginterferon alfa-2a dosing regimen for children with hepatitis C
Apr 01, 2016
Eric Snoeck
Population pharmacokinetic modeling and simulations of dopamine Dd2 receptor occupancy of long-acting intramuscular risperidone-ISM
Mar 01, 2016
Population pharmacokinetics of a three-day chloroquine treatment in patients with Plasmodium vivax infection on the Thai-Myanmar border
Feb 29, 2016
Phase I, dose-escalating study of elisidepsin (Irvalec®), a plasma membrane-disrupting marine antitumor agent, in combination with erlotinib in patients with advanced malignant solid tumors
Feb 01, 2016
Population pharmacokinetic properties of artemisinin in healthy male Vietnamese volunteers
Jan 02, 2016
Platelet Dynamics in Peritoneal Carcinomatosis Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Oxaliplatin
Jan 01, 2016
Pharmacogenomics, Pharmacokinetics, and Pharmacodynamics in the Era of Targeted Therapies
Jan 01, 2016
Excel-Based Tool for Pharmacokinetically Guided Dose Adjustment of Paclitaxel.
Dec 01, 2015
Temporal pharmacokinetic/pharmacodynamic interaction between human CD3ε antigen-targeted monoclonal antibody otelixizumab and CD3ε binding and expression in human peripheral blood mononuclear cell static culture
Nov 01, 2015
Quantitative Characterization of the Effects of Acute Radiation (AR) and Treatment with Filgrastim (Neupogen) on Absolute Neutrophil Counts (ANC) and Overall Survival (OS) in Non-Human Primates (NHP)
Oct 01, 2015
Per Olsson Gisleskog
Isabelle Delor
Philippe Jacqmin
A semi-mechanistic model of bone mineral density and bone turnover based on a circular model of bone remodeling
Aug 01, 2015
Philippe Jacqmin
Using early biomarker data to predict long-term bone mineral density: application of semi-mechanistic bone cycle model on denosumab data
Aug 01, 2015
Philippe Jacqmin
First-in-human, phase I study of elisidepsin (PM02734) administered as a 30-min or as a 3-hour intravenous infusion every three weeks in patients with advanced solid tumors
Aug 01, 2015
Population pharmacokinetics of kahalalide F in advanced cancer patients
Aug 01, 2015
Simulo: a new PK-PD-Disease model simulator
Jun 01, 2015
Quentin Leirens
Philippe Jacqmin
Automatic translation of Bayesian pharmacometric models: the PharmML-to- WinBugs converter.
Jun 01, 2015
Toxicity assessment via drug-drug interaction modeling for trabectedin in patients with advanced malignancies.
Jun 01, 2015
Evaluation of software tools for Bayesian estimation on population models with count and continuous data.
Jun 01, 2015
Pharmacometrics Markup Language (PharmML): Opening New Perspectives for Model Exchange in Drug Development.
Jun 01, 2015
Rilotumumab exposure-response relationship in patients with advanced or metastatic gastric cancer.
Jun 01, 2015
Per Olsson Gisleskog
Integrating Target Mediated Drug Disposition (TMDD) into a minimal physiologically based modelling framework: evaluation of different quasi-steady- state approximations.
Jun 01, 2015
Development and validation of an HPLC-UV method for pazopanib quantification in human plasma and application to patients with cancer in routine clinical practice
Apr 01, 2015
Influence of CYP2B6 516G > T and Long Term HAART on Population Pharmacokinetics of Efavirenz in Rwandan Adults on HIV and Tuberculosis Cotreatment
Jan 11, 2015
SGS BioPharm Day 2014
Nov 13, 2014
For SGS BioPharm Day 2014, Exprimo presented an overview of Modeling & Simulation services.
Population pharmacokinetics of artesunate and dihydroartemisinin during long-term oral administration of artesunate to patients with metastatic breast cancer
Sep 25, 2014
Artemether-lumefantrine co-administration with antiretrovirals: population pharmacokinetics and dosing implications
Aug 10, 2014
Development and validation of an HPLC-UV method for sorafenib quantification in human plasma and application to patients with cancer in routine clinical practice
Jun 01, 2014
Phase I study of elisidepsin (Irvalec®) in combination with carboplatin or gemcitabine in patients with advanced malignancies
Jun 01, 2014
A Target-Mediated Drug Disposition model to quantify the relationship between Otelixizumab in vitro concentration and TCR/CD3 engagement.
Jun 01, 2014
Stability study of oxaliplatin and doxorubicin for intraperitoneal administration with hyperthermia
May 01, 2014
Rate and extent of oxaliplatin absorption after hyperthermic intraperitoneal administration in peritoneal carcinomatosis patients
May 01, 2014
Translational Modeling to Identify Human Dosing of Filgrastim to Improve Overall Survival (OS) in Acute Radiation Syndrome (ARS)
Jan 01, 2014
Philippe Jacqmin
Per Olsson Gisleskog
Population pharmacokinetics of rilotumumab, a fully human monoclonal antibody against hepatocyte growth factor, in cancer patients.
Jan 01, 2014
Per Olsson Gisleskog
Neutrophil dynamics in peritoneal carcinomatosis patients treated with cytoreductive surgery and hyperthermic intraperitoneal oxaliplatin
Dec 01, 2013
Prediction of cytotoxic drug concentrations occurring on the day of autologous stem cell rescue during a high-dose chemotherapy regimen.
Dec 01, 2013
Development and validation of a high-performance liquid chromatography ultraviolet method for lapatinib quantification in human plasma
Dec 01, 2013
Modeling Alzheimer's Disease Progression Using Disease Onset Time and Disease Trajectory Concepts Applied to CDR-SOB Scores From ADNI.
Oct 02, 2013
Isabelle Delor
Philippe Jacqmin
Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat
Oct 01, 2013
Assessment of Maraviroc Exposure–Response Relationship at 48 Weeks in Treatment-Experienced HIV-1–Infected Patients in the MOTIVATE Studies
Aug 14, 2013
Philippe Jacqmin
Model based design and analysis of phase II HIV-1 trials.
Aug 01, 2013
Phase I study of weekly kahalalide F as prolonged infusion in patients with advanced solid tumors
Jul 01, 2013
A Target-Mediated Drug Disposition model integrated with a T lymphocyte pharmacodynamic model for Otelixizumab.
Jun 01, 2013
Real data comparisons of NONMEM 7.2 estimation methods with parallel processing on target-mediated drug disposition models.
Jun 01, 2013
External validation of the bilirubin-atazanavir nomogram for assessment of atazanavir plasma exposure in HIV-1-infected patients.
Apr 01, 2013
Simultaneous online SPE-HPLC-MS/MS analysis of docetaxel, temsirolimus and sirolimus in whole blood and human plasma
Mar 15, 2013
Population pharmacokinetics of hyperthermic intraperitoneal oxaliplatin in patients with peritoneal carcinomatosis after cytoreductive surgery
Mar 01, 2013
Frequencies of Single Nucleotide Polymorphisms in Cytochrome P450 Genes in a Rwandan Population: Difference to Other African Populations
Jan 09, 2013
Tolerability, pharmacokinetics, and pharmacodynamics of the glucokinase activator AZD1656, after single ascending doses in healthy subjects during euglycemic clamp.
Nov 01, 2012
Determination of soluble vascular endothelial growth factor receptor 3 (sVEGFR-3) in plasma as pharmacodynamic biomarker
Nov 01, 2012
Population Pharmacokinetic–Pharmacodynamic Analysis of Neutropenia in Cancer Patients Receiving PM00104 (Zalypsis®)
Nov 01, 2012
Population pharmacokinetics applied to optimising cisplatin doses in cancer patients
Oct 01, 2012
Populational pharmacokinetics of doxorubicin applied to personalised its dosing in cancer patients
Aug 01, 2012
External Validation of the Bilirubin-Atazanavir Nomogram for Assessment of Atazanavir Plasma Exposure in HIV-1-Infected Patients
Jul 12, 2012
Population pharmacokinetics of four β-lactams in critically ill septic patients comedicated with amikacin.
Jul 01, 2012
Philippe Jacqmin
An inhibitor of neuronal exocytosis (DD04107) displays long-lasting in vivo activity against chronic inflammatory and neuropathic pain
Jun 01, 2012
A Target-Mediated Drug Disposition model to quantify the relationship between Anti-CD3 monoclonal antibody and CD3/TCR receptors in Patients with autoimmune diseases.
Jun 01, 2012
Effect of reactivity on cellular accumulation and cytotoxicity of oxaliplatin analogues.
Jun 01, 2012
The Dose-Response Relationship of Peginterferon Alfa-2a and Ribavirin in the Treatment of Patients Coinfected with HIV-HCV
Feb 01, 2012
Eric Snoeck
The evaluation of CYP2B6 inhibition by artemisinin antimalarials in recombinant enzymes and human liver microsomes
Jan 01, 2012
Population pharmacokinetics of PM00104 (Zalypsis®) in cancer patients
Jan 01, 2012
Multinomial Logistic Functions in Markov Chain Models of Sleep Architecture: Internal and External Validation and Covariate Analysis
Sep 01, 2011
Quantitative Assessment of First Night Effect in a Polysomnographic Insomnia Study through a Multinomial Mixed-Effect Markov-Chain Model.
Jun 01, 2011
Bilirubin-a potential marker of drug exposure in atazanavir-based antiretroviral therapy.
Jan 12, 2011
Multinomial logistic functions in Markov-chain models for modeling sleep architecture: internal validation based on VPCs.
Jun 01, 2010
Mixed-effects modelling of the interspecies pharmacokinetic scaling of pegylated human erythropoietin
Jun 27, 2005
Population pharmacokinetic analysis of pegylated human erythropoietin in rats.
Jun 26, 2004
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2016 SGS Exprimo


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Indoor Air Quality
Video Overview
The product is a quaternary-based biocide, formulated in tablet form and enclosed in a plastic housing which in turn is sealed ultrasonically to an absorbent white filter pad. Water is absorbed by the pad and "wicked" to the tablet, resulting in the immediate, but controlled, release of the powerful biocide. PanPads can be used in any condensate pan arrangements, either horizontally or vertically. Their low profile fits most pan configurations, and they last three months or more. Formulated buffering agents help protect pan against corrosion. When used as part of the Clean Coil Program, equipment is assured of optimum performance at the lowest possible energy cost.
Air conditioning and refrigeration evaporator or cooling coils cool the air that is brought across them. In the process, moisture can be removed from the air, resulting in condensate. This condensate is collected in the condensate pan and drained away. Without proper treatment, bacteria can begin to grow in the pan, clogging the drain hole and resulting in overflow. In addition, this bacteria can also cause musty odors as well as respiratory ailments, contributing to an indoor air quality (IAQ) problem. Use of PanPads kills this bacteria, preventing these problems.
NOTE: This product is not registered for sale in Canada.
Packaging Size Part Number Additional Info.
PanPads-5 Slim 4295-36 Treats up to 5 tons
PanPads-5 4295-34 Treats up to 5 tons
PanPads-15 4296-24 Treats up to 15 tons
PanPads-45 4296-45 Treats up to 45 tons
This product must be used in accordance to the following directions by HVACR professionals only.
Place in air conditioning or refrigeration condensate drain pan.
Literature Downloads
Download the product bulletin and other relevant literature here.
Download a low resolution file of the product label here.
SDS Information
Read and understand the product's Safety Data Sheet for precautionary and first aid information.
panpads; Pan Pads; pan pads


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If you love eating seafood, you have to check out Orange Karenderia in Salinas Drive, Lahug, Cebu City. The seafood restaurant has gained popularity among Cebuanos and tourists for its very delectable tuna dishes like the Crispy Buntot, Paga ng Tuna, Tuna Belly, Tuna Bihod (eggs) and Tuna Bagaybay (gonad).
Non-seafood lovers will also enjoy dishes like Garlic Chicken and Sisig. Orange Karenderia is a great place to bring visitors and try one of the best seafood restaurants in Cebu City. Check out our full review at Kalami Cebu Blog.


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On November 6th at 10am, students in high schools and colleges across the country will walk out of class and march to the polls to cheer each other on as those eligible cast their votes. By bringing together young people across communities, issues, and organizations, we will ensure young people show up to the polls in record numbers and send a bold message to politicians and the country that young people are unified in our demand for change. Even if students aren't old enough to vote, they are still encouraged to lead and participate in the walkout to help make our message heard.
Walkout to Vote is a project of the Future Coalition–a national network of youth-led organizations and initiatives. The Future Coalition works collaboratively to share resources and ideas, all with a common goal of making the future a better, safer, and more just place for everyone.
Find an Event: https://walkouttovote.org/#map