text:
❤No Mambo Jambo.No Fake Hope❤What He/She Think/Feels/Wants?I'll UNFOLD everything. If U can Face TRUTH❤CALL ME❤ I ...
Special Offer: ❤Accurate n Fast❤Let's Get Ur Life Back❤Your Satisfaction is Priority❤
❤❤❤❤EXPERT IN LOVE & RELATIONSHIP ISSUES. 99% Accuracy & 100% Honesty.FAST TYPIST IN LIVE CHAT SESSION. NO ...
Special Offer: 1 HOUR IS $180.00 1/2 hour 90.00 this is for cyber Monday Only
Search Results for love whisperer
Love Whisperer Daniel G. (love_whisperer_daniel_g.)
LOVE WHISPERER DANIEL G. Hello! I am a gifted seer and psychic blessed to empower people with life's truths and spiritual guidance needed in order to get through these difficult and uncertain times. I'm referred to as Love Whisperer Daniel G. because I sense compatibility and see where a relationship is headed before ...
$20.00 per minute Special Offer: Prepaid only (10 Minutes $99.99) (20 Minutes $179.99)
advice breakup divorce empathic future intuitive love advisor love and relationships. love whisperer love whisperer daniel g. lovewhisperer
Love Assurance (loveassurance)
Love And Relationship, Marriage, Soulmate, Lesbian/Guy, Heart Reader, Mind ... I can you about your lovelife,present,past and future. I will tell you what is coming for you and what is good for you. Together we can walk and talk into the light to correct your stumbling blocks and issues, to open the doors to all you are entitled and will know what is coming for us. I will tell you what ...
My $10 deal: 10 minute. Love and Career life Reading
$0.99 per minute Special Offer: 25 Minutes in 20$,
Love astrology and many more business career lifepartner oracle card relationship soulmate tarot card
❤ Spiritual Advisor - Psychic Visionary ❤ ~ Are you confused? ~ Lost in clouds of despair? ~ Need help now? ~ Clear that fog of confusion by discovering the answers to your relationship, love, career and other life questions. Allow my Spiritual Giftings to unfold the arriving events about your future through an amazing flow of second sight visions! ...
My $10 deal: None at This Time - No Per Minute
$5.73 per minute Special Offer: 10 minutes $45 - Please read my Profile before coming into Chat.
clairvoyant dream analysis dreams duval love love advice medium michael michael duval psychic relationship
Barb's Readings Honest readings on all love situations
$10.00 per minute Special Offer: NO FREE READINGS. YOU MUST HIRE UPON CONTACTING ME.
Tarot Reader, Psychic, Licensed Spiritual & Metaphysical Practioner/Counselor I have been reading Tarot cards since I was little, being very drawn to all the possibilities offered by everything that surrounded me. What you will get from me comes from various paths. I am able to pick up energies from the cards, the Universe, yourself, my Guides, and your Guides. Please be prepared to ...
$1.50 per minute
EFT Empath Friend Healing Lithomancy Psychic Reading Reiki Runes Spiritual Counselor Tarot Reader
Soni UK I am offering my services here and hope I am able to help those in need of support and insight to your love and life problems. Hope to hear from you soon. Blessings :) j^ From the angels ^j "We're aren't that difficult to hear, if you will listen for us with an open heart. Most of the time ...
$15.99 per minute
angels astrologer divorce guides love reading psychic psychic reading soni uk soniuk tarot
Psychic Andy R Honest and compassionate psychic guidance and distant energy healing, led by Spirit. Fast typing. Let me help you bring more light into your life today! I've been clairvoyant, clairaudient, and empathic since I was a child, by this I can easily gather information by "seeing," "hearing" and "feeling" the ...
$0.99 per minute Special Offer: Free connection Before hire
Angelique379 Blessed are those who Seek and Dare to Believe.* Hello! I'm Angelique. I've been reading tarot and Knowing for 25+ years. I am honest, fair, and very, very real. Please understand. I Must tell you what I See. Anything less is a disrespect to you & the Forces that granted this Gift. I can't always deliver ...
My $10 deal: Five cards on one question only.
$1.25 per minute
Whispering Spirit (sacredspace)
Psychic Medium Readings Kevin is a natural born Psychic medium. He has 30 years International Experience Online connecting people with their loved ones in Spirit. Give him the opportunity to re-unite you with your loved ones now. As an Intuitive Psychic he can also offer guidance in any areas of your life that currently concerns you
$0.90 per minute
accurate authentic clairsentient clairvoyant empathic finance job spiritualism clairvoyant healing life after death loved ones psychic development reiki relationship spirit
Natalie Kauftheil With rare psychic gifts I never take for granted, I can tell you what someone's thinking or planning. I am always loving caring and give a straight forward read for you. I only tell you the truth of what I see never sugar coating. Love readings, finances, so if you want to know when that job is coming ...
$4.99 per minute


text:
Are Chackerian Likes to Make Technological Advances
For Ara Chackerian, the point of coming up with new ideas is so he can help other people have a better experience no matter what they do or what part of the industry they're in. He knows what people want and he's not afraid to make it happen so they have a chance to get more from everything he's offering. By looking at these options, people will have a better chance at a brighter future thanks to the work he does. Ara Chackerian always wanted to make sure he could help people see what they could get from these opportunities. It's his goal to always help others and always give them the options they need to succeed. He believes he can make things easier and make sure people have all the opportunities they need to succeed. When he came up with these ideas, Ara Chackerian knew what he wanted to do and knew it would be an important part of all the work he did. You can visit his about.me page to see more.
Thanks to the experience he had in the technology industry, Ara Chackerian could keep helping more people than what he knew about when he first started. He pushed forward to make sure there were ways he could give back and that's how he made things easier for himself and for the people he worked with. Chackerian continues showing others they can have positive experiences and that's what allows him to do business the right way. No matter how hard he has to work to help people, he can come up with new solutions for success. You can visit angel.co for more.
After Ara Chackerian learned about the right way to do things, he felt comfortable helping others realize he was among the best in the industry. It showed them he was making positive choices and he was coming up with all the right solutions. Between his hard work and the work he did with other people, Ara Chackerian could create a positive experience in the world around him. He wanted people to get the relief from depression that would help them feel better about themselves and the way they lived.
Click here: http://californiablog.org/content/exploring-tms-ara-chackerian-non-invasive-mental-health-treatment-targets-brain

subset: commoncrawl


text:
ACTEM Listserv
The ACTEM listserv has been established as a mechanism for information exchange and problem resolution for use by those interested in enhancing and influencing education though the use of technology in Maine schools. It is intended to provide a statewide forum for the discussion of all matters relating to the educational technology in Maine consistent with ACTEM's mission and vision.
Policy Statement
ACTEM listserv subscription is reserved for current members and those who are interested in education and technology in Maine. ACTEM's listserv is not moderated and messages are not approved before posting.
Postings may include questions and discussion items, ACTEM announcements, technology position vacancies, professional development opportunities and items that can be considered "public service" in nature to the listserv. Be considerate of ACTEM's audience.
ACTEM is a non-profit, professional organization therefore listserv postings that promote or advertise goods or services are forbidden.
By subscribing to the ACTEM listserv you are confirming that you have read and agree to the terms of our listserv policy and guidelines.
Listserv Guidelines
Listserv Registration Procedures
The ACTEM listserv is a great way for individuals in the field of educational technology to stay abreast of the latest happenings in this new and exciting frontier. You will receive updated information on new technology initiatives occurring at both the state and local level. Additionally, your subscription will allow you to share ideas and access a pool of knowledge that would otherwise be difficult to obtain, join today!
How To Subscribe to the main ACTEM List
To subscribe to the ACTEM listserv, send a message to: email@example.com
In the text of the message enter the following:
subscribe actemlist first last
(where "first last" is his/her real name).
Don't put anything else in the body of the letter - just that one line.
That starts the process.
A confirmation letter will come back to that user's e-mail
address requesting that he/she reply to confirm the subscription. Just
follow the instructions in the letter. Listserv will send a second letter
saying that the person is subscribed.
Finally, listserv will send a third letter, explaining how to unsubscribe.
You may leave the list at any time by sending a "SIGNOFF ACTEMLIST"
command to firstname.lastname@example.com.
You may also go to http://lists.maine.edu to control your account on the ACTEMlist. Once you've successfully joined the ACTEMlist, you can control your account to do things like change your email address or unsubscribe from the list.


text:
If you need to know about building and retaining assets in Europe, you need Fund Radar.
Fund Radar was founded specifically to provide asset management professionals with authoritative and innovative research on all aspects of European fund industry developments and dynamics.
Current key services offered are bespoke consultancy and publication of the widely recognised Fund Radar monthly report series. "Fund Radar – First Sight" and "Fund Radar – Second Sight" combine latest data with cutting edge commentary on both domestic and cross-border markets to assist fund groups' senior management with their strategic planning.
MackayWlliam's key personnel each have over twenty five years industry experience and against continually changing stock market horizons their objectives are:


text:
Meeting of the Scientific Committee of the BMC to be held in the Reading Room of the Mathematics Department, University of Swansea, on 18 April and 19 April 2007.
The meeting is in TWO parts. First part Wednesday 18.15 - 19.00 in the Reading Room of the Mathematics Department. Second part Thursday 13.00.
[Item 9 (Galway 2009) will be taken at the Wednesday meeting along with some other items]
Minutes of the Scientific Committee of the BMC held in the Mathematics Seminar Room, University of Swansea, from 13.00--14.00 on Thursday 19 April, 2007.
Rob Archbold, Garth Dales, Charles Goldie, Iain Gordon, Niels Jacob, Eugene Lytvanov, Edmund Robertson (Chair), James Ward, Chris Wood (Scribe).
The following suggestions were discussed:
Edmund Robertson (St Andrews) - until 31 May 2008 email@example.com
Rachel Camina (Cambridge) - until 31 May 2007 firstname.lastname@example.com
Garth Dales (Leeds) - until 31 May 2008 email@example.com
Charles Goldie (Sussex) - until 31 May 2009 firstname.lastname@example.com
Rob Archbold (Aberdeen) - until 31 May 2007 firstname.lastname@example.com
Iain Gordon (Edinburgh) - until 31 May 2008 firstname.lastname@example.com
Francis Clark email@example.com
Niels Jacob firstname.lastname@example.com
Steve Donkin firstname.lastname@example.com
Maurice Dodson firstname.lastname@example.com
Chris Wood email@example.com
Ted Hurley email@example.com
James Ward firstname.lastname@example.com
Jim Howie email@example.com
BMC AGM Representative:
Tony Mann (Greenwich) firstname.lastname@example.com


text:
The Sunday Youth Rides program is intended to showcase the numerous intermediate and advanced trails throughout Hartland and Partridge Hills. Lead by experienced guides, you can expect a 3 hour ride (with snack breaks), full of challenging but rewarding riding. Each ride is uniquely adapted to that day's participants, if it's a faster group, the ride will be paced that way, if it's a group of less experienced riders, the pace will reflect their needs. If it's a mixed group the guides might opt to split the group up. The guides will offer skills feedback to participants throughout the ride, mini lessons on trail are typical.
Location: Hartland Mountain Bike Park (Mt Work, West Saanich)
Sundays 10am-1:00pm
*September 18th- November 20th | 8 classes | $279
*No class October 9th and 30th (Thanksgiving & Halloween)
Ages: 10-16 years. Group may be split based on age and abilities. Participants should be confident riding blue square trails up and down at moderate speeds, and should be open to learning to ride black diamond trails. Please bring a spare tube, hand pump, and snack and water, in either a hydration pack or good fitting pack. To find out if this program is the right fit for your son or daughter, contact firstname.lastname@example.com
Dropping in? We need 24 hours notice. Email email@example.com to confirm please.


text:
Our waiting area called "Svalbard" is a Viking longhouse-style building which was designed to complement the existing Scandinavian complex. It is named after the island archipelago north of Norway and beautifully reflects the "natural place" ethos of Roucan Loch.
Svalbard is the summer home of the Barnacle Geese who winter here on the Solway and often visit Roucan Loch. The geese theme continues inside the waiting room with flying geese engraved onto the windows and the poem "Something told the wild geese it was time to go" by Rachel Field, etched on a wooden plaque.
"Svalbard" means "a land at the end of the ocean", in old Norse. In the depths of a Scottish winter, we feel this could bring comfort to a lot of people who have lost someone. The flight of the geese may be symbolic of our loved ones who are no longer with us, resting in a land at the end of the ocean.
The waiting area enhances Roucan Loch and will provide a bright and welcoming place for people needing a coffee after a long journey.
Svalbard serves not only as a very practical building where families are encouraged to gather before a service, but also as a shelter from the strong winds, rain and the snow of winter. It is also possible to view our many garden birds and red squirrels feeding, as Svalbard can also act as a bird hide and has a nest box camera with viewing screen installed.


text:
Recent Posts
Tools for Calming Down
May 8, 2019 By Sandra Sunquist Stanton Leave a Comment
The Cozy Comforter Weighted vests can calm an agitated nervous system. These folks based out of Menomonie make them to order: www.weightedwearables.com https://weightedwearables.com … Read More
Max Your Mind Video
November 12, 2018 By Sandra Sunquist Stanton Leave a Comment
Frustrated with your brain? Wishing you could remember where you put your car keys? Mature brains-those over 30-sometimes leave us stranded. Max Your Mind explains the process with humor and hope. … Read More
CVLA Interview Mind Maxing Conference
August 9, 2018 By Sandra Sunquist Stanton Leave a Comment
Hope you can join us to Max Your Mind on Saturday, October 6 at The Center (Day Retreat Center) Eau … Read More


text:
From the Palm Beach Post
Florida Bar President Mayanne Downs predicts some Florida attorneys will pay the ultimate professional price for foreclosure-related wrongdoing – disbarment – as investigations mount statewide.
"It's the death penalty of the legal profession," said Downs, who spoke to The Palm Beach Post's editorial board this week about legislative proposals affecting the courts and the state's ongoing foreclosure tumult.
The bar, which is responsible for investigating complaints of attorney misconduct, has 222 foreclosure fraud cases open on 157 lawyers.


text:
This blog is supposed to be all encompassing of every aspects of our life, however, until I get a better camera for portraits, beauty and fashion posts, I'm going to stick to some recipes and more trivial things.
I've honestly never had an Italian Soda, but at a girls night the other night, my friend suggested we make them. She even had a Keto version for me (although substituting the syrup for sugar free was the main Keto change)! They are very easy to make and now that I have been on Keto, I am always looking for new things to try, especially on the sweeter side.
To make an Italian Soda you will need: Flavored Syrup (sugar free if it fits your fancy), sparkling water, we used S. Pelligrino, and half and half or heavy whipping cream.
Since starting Keto, flavored syrups have been amazing in my bulletproof coffee. I have also experimented using them elsewhere since it's hard to find a delicious Keto dessert that doesn't have the underlying aspartame taste. For my Italian Soda I used, 6 pumps of the Torani – Sugar Free: Black Cherry and went heavy on the heavy whipping cream, and poured the S. Pelligrino to the brim. It was delicious. I want to try this out with the Torani – Sugar Free: Cookie Dough flavoring (currently in the mail). I have no idea if it will be delicious or disgusting, but I'm willing to take that risk.
Comment below and let me know your favorite Italian Soda substitutes and flavorings!


text:
You've heard it a million times that life is short, you live your youth only once and you should truly enjoy a care-free life. What's most important is to know how young you'd feel if you never knew your age. Yet there are some things that are better done when you're young. Once you start a family and responsibilities take a hold of you, there are many things at stake if you do one silly thing at a wrong time and wrong place, such as your dignity and your social status.
In youth, luckily, there's nothing at stake. Anything you do can only teach you a lesson you'll find important later in life. You have both the energy and the ability to take spontaneous actions and live your life without care. Before you realize that you're wasting your youth and you can no longer be irresponsible, we got you a list of things you simply must do while you're young, wild and free.
Grasp your life with both hands and squeeze all the good stuff your youth offers. You learn a new lesson with each experience, so make sure you'll learn a lot of important life lessons that will help you build a life you'll love. No matter how young you are, here are 10 things you must do before it's too late.
Travel as Much as You Can
Before you get trapped in your everyday grown-ups-routine, spend all your savings on traveling around the world. Visit the country you always wanted to see. Meet people from different cultures. Make small local trips often. Pack your bag and get out there. There is a lot around the world you need to see.
Go Out as Often as You Can
Your parents or other relatives have probably asked you once why are you still home at Saturday night when you can go out with your friends and have fun. While there are undoubtedly times when you're going to feel down and not in the mood for going out, try to go out as often as you can when you're young and full of energy. As you grow, you will only be getting lazier, less interested and less enthusiastic about having a beer at a bar with your friends.
Learn a Language
Wondering why would you spend more time reading, learning and educating yourself? Simply because there will never be a better time for learning something that you never know when it may come in handy than now, when you have a plenty of free time. It may not necessarily be time well spent, but once you start building a career, having a second or third language under your belt will be a big advantage of yours.
Go See Your Favorite Musician Perform Live
Whether it's a local celebrity or a world-famous star, go see your favorite musician play live. Don't say you can go to their concert some other time, because they just might retire or something else could happen and you'll carry a regret all your life. Grab your ticket for your favorite musician's very next show and have the time of your life.
Take Risks
Although life itself is a series of risks and rewards, take all the risks you can when there's nothing much to lose. Whether you want to create a news website or open a restaurant, give your "crazy" idea a try and see how it turns out for you. Despite being a risky move, it might just turn out to be your early career breakthrough.
Find Your Best Friend
Finding your best friend can be a tricky, confusing and emotional path, but the earlier you start looking for it, the bigger your chances are to find that one person with whom you can build a long-lasting friendship. While you surely should hang out with tons of friends in your youth, you need only one friend to refer to as best friend.
Try a New Haircut
Before you decide to cut your hair as you always do, try a new haircut instead and try to keep it longer than ever. Regardless of whether you're a girl or a boy, don't settle for the same style for such a long period. Do whatever you want with your hair or your clothes. In worst case, you will discover what does and what does not work for you early in your life.
Find a Job You Love
Although not impossible, finding your dream job at early age is quite difficult these days, mostly because a big number of teenagers and young adults haven't found themselves as individuals yet, as well as their dream jobs. But whether you're still in high school or college, you could surely use some cash. This way, you are also increasing your chances of discovering what your dream job is.
Spend a Weekend Partying
As the years go by, the chances of pulling an "all-weekender" are largely decreasing. Your responsibilities will make it almost impossible to spend an all nighter, yet alone partying 2-3 consecutive nights. Before they take hold, check how big of a party animal you really are. It's really worth trying.
Have a Hangover to Remember
There's nothing more insane than getting wasted to a level that will give you a hangover to remember next day. Since we are curious by nature, getting drunk is more common than one would guess – everyone gets drunk at least once. Experience what it's like to be so hungover that you can feel your body saying "No" to your commands. Get this out of your system when you're still young, so you can be better at having a full control over your life.
Of course, making mistakes, being stupid and experimenting doing all sort of things are naturally a part of your youth, but don't worry, it is the only way to gain experience and grow to an intelligent, responsible and confident person. But you can significantly reduce the number of mistakes in your life as an adult if you do these 10 things while you're young. So brace yourself and start shaping your future!


text:
The group meets over pizza and beer or soft drinks, ranging and rambling chat, in addition to interesting and informative talks. Over the years we've had talks about design, continuous integration, docker, optimisation, side projects, learning, katas, devops, testing, joomla, minihacks, lightning talks, PHP7 and many other things. The group is diverse, welcoming, sociable, relaxed, irreverent, informative and fun.
Code of Conduct:
to (Europe/London time)
About AberdeenPHP
Aberdeen PHP User Group aims to provide a regular meeting for developers in Aberdeen and the surrounding areas to get together and discuss just about anything in and around the PHP Community.
More details
On Twitter
At Fifth Ring
This is part of these Curated Lists


text: Lendo 1,901,681 Posted February 23, 2009 I hear you man, i'd been thinking about the boots or the 2 eye mocs. The Quddoy bluchers are nice too though. I need a magic 8-ball, some tea leaves, and chicken bones or some shit to figure it out. 0 Share this post Link to post Share on other sites


text:
The latest Blu-ray sales figures from NPD Group have been far from stellar since the demise of the competing HD DVD format back in February.
Sales of standalone Blu-ray players were down 40 percent from January to February, then up 2 percent from February to March, following the death of HD DVD. Hardly the sales spike many predicted after Toshiba canned the competing high def format.
DVD upscalers blamed
Ross Rubin, director of industry analysis at NPD claims that cheaper upconverting DVD players (on average $70 in the US right now) are still the preference for the majority of consumers, when compared with far more expensive standalone Blu-ray players (costing American consumers $300 and up).
NPD claims Blu-ray sales should pick up nearer to Christmas, when prices should drop down to the $200 range, while research firm ABI Research are even less optimistic, claiming it will be later in 2009 before Blu-ray really goes mass market.
Meanwhile Microsoft refuses to confirm support of Blu-ray for its Xbox 360 console and seems to be sticking to its original strategy of supporting movie downloads.


text:
Thomas Cook – Can I get a cheaper deal with Holiday Gems?
Thomas Cook is one of the most well known holiday names in the UK. But big names don't necessarily guarantee the lowest prices for 2020. You might find that Holiday Gems can get you the same or a similar holiday deal cheaper.
How can Holiday Gems find me a cheaper deal than Thomas Cook?
First and foremost, Thomas Cook is a tour operator. This means that the company operates their own flights and have a large number of own-brand hotels.
Some customers like the uniformity of this way of holidaying. However, there are a few downsides. Many find the reduced choice in flights and accommodation restrictive.
In contrast, Holiday Gems is a booking agent which gives us the freedom to take advantage of exceptional holiday deals from many different airlines and hotels. We specialise in comparing all these deals from the range of airlines, hotels and resorts and we pass these savings onto you.
So you could save money in a range of different ways, like flying out from an airport closer to your home, to discounts and deals on hotels that you just can't get with Thomas Cook.
You can also book safe in the knowledge that Holiday Gems sell ATOL bonded holidays. ATOL is backed by the British government and means you're protected when you book your holiday with us.
Want to find out more? See if we can find you a better holiday deal than Thomas Cook. Call us on 0871 943 1300 10p/min + network extras


text:
Lund University was founded in 1666 and is repeatedly ranked among the world's top 100 universities. The University has 40 000 students and 7 600 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.
The Division of Synchrotron Radiation Physics (www.sljus.lu.se) is a part of the Department of Physics and has more than 40 employees. The focus of the research is experimental studies of electronic, structural and chemical properties of materials, accelerators for Synchrotron radiation and instruments and methods for Synchrotron radiation. At the Division we use and develop a wide range of Synchrotron- and lab-based techniques, such as X-ray photoelectron spectroscopy/imaging and X-ray diffraction/imaging. We also host one of Sweden's largest facilities for scanning probe microscopy. We are additionally engaged in the development of the MAX IV Laboratory in the fields of beamlines, experimental stations, techniques for Synchrotron radiation and the accelerator systems.
MAX IV (www.maxiv.lu.se/) is a national large-scale research laboratory hosted by Lund University and situated within biking distance from the Department of Physics. It provides scientists from Sweden and the rest of the world with the most brilliant Synchrotron radiation source and instrumentation for research in areas such as materials science, structural biology, chemistry and nanotechnology. Fully developed it will receive around 3000 scientists annually and host around 26 beamlines (www.issuu.com/lundsuniversitet/docs/strategyreport_2016_2026).
NanoLund (www.nano.lu.se) is the Centre for Nanoscience at Lund University. NanoLund is today Sweden's largest research environment for nanoscience, engaging approximately 270 PhD students and scientists in the Faculties of Engineering, Science, and Medicine. It operates Lund Nano Lab, a state-of-the-art cleanroom for the synthesis, processing, and characterization of semiconductor nanostructures.
In order to rationally design semiconductor nanostructures with realistic applications in future electronics and photonics, it is crucial to reach a fundamental understanding of their structure-function relationship at length scales from microns to the atomic scale. In nano-objects, surfaces and interfaces are of particular importance, as they often directly define device functionality and strongly influence local electrostatics and strain fields.
This project aims to study the structure and influence of semiconductor nanostructure surfaces and interfaces using cutting edge Synchrotron based diffraction, spectroscopy, and imaging techniques.
In the research we will use and develop a wide range of Synchrotron-based techniques, such as X-ray photoelectron spectroscopy/imaging and X-ray diffraction/imaging. This will allow us to study detailed geometric and electronic structure of both particularly interesting surfaces and interfaces as well as fully operational devices – even in-operando. The highly advanced Lund III-V semiconductor nanowire platform will be a basic building block to create structures that are both interesting model systems as well as functioning devices using quantum effects for functionality. Structures of both 3-, 2-, 1-, and 0-dimensional character will be investigated. The overarching goal of the project is a new understanding of how (opto-)electronic nanostructures function on the atomic scale.
The project is supported by major grants from the Swedish Research Council and the Wallenberg Foundation.
Work description
The main duty involved in a post-doctoral position is to conduct research. Teaching may also be included, but up to no more than 20 % of working hours. The position shall include the opportunity for three weeks of training in higher education teaching and learning. The postdoctoral fellow is expected to interact with the master students and the PhD students in the research group and contribute to meetings and seminars.
This project aims to study the structure and influence of semiconductor nanostructure surfaces and interfaces using cutting edge Synchrotron based diffraction, spectroscopy, and imaging techniques.
Work will be carried out at the new Synchrotron MAX IV in Lund as well as other synchrotrons world-wide. An important aspect will be the use of Hard X-ray diffraction/imaging techniques to study the strain and structure in nanowire-based devices and complex structures. However, photoemission-based spectroscopy/imaging will also be part of the work. Advanced X-ray imaging techniques such as Coherent Diffraction Imaging or Bragg Ptychography can be used and further developed. The successful candidate will interact with experts in manufacturing of semiconductor nanoscale structures and devices to design relevant structures. The work will be performed in collaboration with several other researchers at the institute as well as a number of Ph.D. students and master students.
Qualification requirements
Appointment to a post-doctoral position requires that the applicant has a PhD degree, or an international degree deemed equivalent to a PhD, within the subject of the position, completed no more than three years before the last date for application.
Additional requirements:
The subject of the doctorate degree should be in physics, chemistry, nanoscience, or equivalent.
Very good oral and written proficiency in English.
Assessment criteria and other qualifications
This is a career development position primarily focused on research. The position is intended as an initial step in a career, and the assessment of the applicants will primarily be based on their research qualifications and potential as researchers. Particular emphasis will be placed on research skills within the subject.
For appointments to a post-doctoral position, the following shall form the assessment criteria:
A good ability to develop and conduct high quality research. Teaching skills or related experience, such as mentoring, supervision, or training in equipment use.
Additional assessment criteria are:
Important personal qualities are, beside creativity and a curious mind, the ability to work both independently and in a group, and experience in the scientific interaction with researchers from other disciplines and in other countries.
Terms of employment
This is a full-time, fixed-term employment of a maximum of 2 years. The period of employment is determined in accordance with the agreement "Avtal om tidsbegränsad anställning som postdoktor" ("Agreement on fixed-term employment as a post-doctoral fellow") between Lund University, SACO-S, OFR/S and SEKO, dated 4 September 2008.
|Type of employment
|Temporary position longer than 6 months
|Contract type
|Full time
|First day of employment
|As soon as possible for two years
|Monthly salary
|Number of positions
|Working hours
|Skåne län
|Reference number
|Union representative
|Last application date
|27.Feb.2018 11:59 PM CET


text:
St. John's Wort Collection Mined for Its Medicinal Value
A unique collection of St. John's wort (Hypericum) curated by Agricultural Research Service (ARS) scientists in Ames, Iowa, is providing university collaborators with genetically diverse, well-documented sources of this herb to use in studies examining its medicinal potential.
In collaboration with Mark Widrlechner, a horticulturist with the ARS crop genebank at the North Central Regional Plant Introduction Station in Ames, scientists from the Center for Research on Botanical Dietary Supplements (CRBDS) are screening 180 germplasm accessions of St. John's wort for biologically active compounds. Some may be worth evaluating further in clinical trials for their potential to combat viral infections, reduce inflammation or improve digestive health.
Established in 1948, the ARS Ames crop genebank curates more than 50,000 accessions of ornamental plants, maize, oilseeds, vegetables and other crops, and provides them to researchers for many applications. Accessions with medicinal or nutraceutical value include Echinacea (purple coneflower), Hypericum, Prunella (self-heal) and Actaea racemosa (black cohosh). ARS horticulturist Luping Qu curates the collection and Widrlechner coordinates its use for research at CRBDS, one of six Botanical Research Centers funded by the National Institutes of Health from 2005-2010.
The Hypericum collection at Ames was started in the 1990s and today encompasses about 60 species collected from around the world. This diversity has enabled investigations of genetic, environmental and developmental factors affecting the quantity and quality of bioactive compounds, as well as their modes of action.
Of particular interest is how these compounds interact, and whether those interactions are critical to human health benefits. In a recent issue of Pharmaceutical Biology, researchers noted that combinations of four compounds from St. John's wort (amentoflavone, chlorogenic acid, pseudohypericin and quercetin) were more effective at reducing inflammation in mouse macrophage assays than when each was used alone.
Widrlechner's collaborators include Diane Birt, Kimberly Hammer, Matthew Hillwig, Jingqiang Wei, George Kraus, Patricia Murphy and Eve Wurtele at Iowa State University; Jeffrey Neighbors, David Wiemer, Wendy Maury and Jason Price at the University of Iowa; and Joe-Ann McCoy, formerly with ARS.
ScienceDaily (Mar. 30, 2010)
» For a more detailed discussion of Extracts of St. John's wort – and the medical studies that support its use – see the article on our website at:
Hypericin: the active ingredient in Saint John's Wort
by A.Y. Oubre
Hypericin, a photochemical extracted from St. Johns Wort (Hypericum perforatum) and related species, has been shown to have potent, broad spectrum antimicrobial activity. This compound is an aromatic polycyclic anthrone, a class of colored or pigmented chemical substances which have photosensitizing activity. In both in vitro (laboratory) and in vivo (animal) studies, low, non-toxic doses of hypericin significantly inhibited the replication of several viruses, including HIV, influenza A, cytomegalovirus (CMV), Herpes simplex 1 and 2 (HSV-1 and HSV-2), and Epstein-Barr virus (EBV). Hypericin and its chemical relative, pseudohypericin, produce antiviral activity through a different mechanism of action than do AZT and other nucleoside antiviral agents. Hypericin does not appear to directly alter the activity of reverse transcriptase although it does block the formation of HIV synctium. Recent findings have shown that the antiretroviral action of this compound disrupts uncoating of the lipid envelope of both DNA and RNA viruses, thus preventing infected cells from releasing HIV copies. Theoretically, hypericin and AZT, in combination, may have synergistic antiviral effects against HIV. On the other hand, hypericin actually may increase the toxicity of antiretroviral nucleosides such as AZT, ddI, or ddC.
Traditionally, extracts of St. Johns Wort (which contain hypericin) have been used as an antidepressant, possibly by acting as a MAO inhibitor. The psychotropic effects attributed to hypericin in St. Johns Wort extract suggest that the pigment compound can cross the blood brain barrier (possibly treating neuropsychological symptoms such as dementia). Laboratory investigations indicate that hypericin may be beneficial as an HIV therapy. However, its administration should be carefully monitored by a physician. The levels of hypericin found in most commercially available extracts of St. Johns Wort generally are not sufficient to be therapeutically effective against viral infections.
Liver function should be tested periodically in persons taking hypericin. Also, extreme photosensitivity has been observed in a few cases of people taking this high doses (in excess of 10 mg per day) of this compound. Finally, there is a very small possibility that adverse reactions could occur on occasion between hypericin and other foods or drugs which interfere with MAO inhibitors.
Active principles in St. Johns Wort
The quantity and quality of active principles in Hypericin species vary according to geographical locale, climate, time of day, and time of year. St. Johns Wort contains dianthrone derivatives, mainly in the form of hypericin and pseudo-hypericin as well as flavonoids. Small amounts of coumarins, phenolic carboxylic compounds, phloroglucinol derivatives, monoterpenes, sesquiterpenes, n-alkanes, n-alkanols, carotenoids, and beta-sitosterol are present. The roots contain zanthones. Practitioners and consumers should note that St. Johns Wort extracts, whether standardized or not, consist of other active ingredients in addition to hypericin and pseudohypericin.
Pre-clinical studies
Both in-vitro (test tube) and in-vivo (animal) pre-clinical studies suggest that hypericin (and, to a lesser extent, pseudo-hypericin) may have therapeutic benefits for HIV infection and other retroviral diseases. Certain compounds other than hypericin extracted from Hypericum species have antibiotic activity. marked antiretroviral effects, however, have been reported primarily for hypericin which is isolated mainly from Hypericum perforatum. However, synthetic hypericin has been used in recent studies.
In in-vitro and in-vivo studies, both hypericin and pseudohypericin (extracted from Hypericum triquetifolium) had antiviral activity against several retroviruses. In one experiment, mice were simultaneously injected with low doses of the compounds and with Friend leukemia virus (FV). This aggressive retrovirus normally causes rapid splenomegaly (swelling of the spleen) and acute erythroleukemia in mice. However, these symptoms were effectively suppressed by the addition of hypericin. Splenomegaly had not occurred ten days after infection at the close of the study. No infectious virus could be recovered from the spleen. Also, viremia normally associated with FV was absent. Mice treated with hypericin and pseudohypericin survived a much longer time than mice treated with a toxic antiviral (N3dthd). Unlike most antiretroviral drugs, hypericin (given in a single dose of low concentration) was effective without being cytotoxic. Even when it was administered after viral infection had already started, it still inhibited the onset of disease.
In in-vitro studies, mouse cell lines were infected with radiation leukemia virus (Rad LV) and then incubated with hypericin. The activity of reverse transcriptase in these cells was suppressed through indirect mechanisms. In contrast to nucleoside analogues, polycyclic diones such as hypericin interfere directly with the viral replication cycle during stages in which virions are assembled or intact virions are shedded from immature cores. Alternatively, these aromatic compounds may directly inactivate mature retrovirus that contains normal, assembled cores. Other findings indicate that hypericin is able to inactivate virions and block viral release from infected cells by interacting with the cell membrane.
Unpublished data show that hypericin disrupts the formation of synctia in HIV disease as well as in de novo infection of cells. In in-vitro studies, hypericin showed selective activity against HIV and modest inhibition of reverse transcriptase. In vitro research also revealed that hypericin lowered viral activity in whole human blood taken from HIV infected persons. "Wild" strains of HIV taken directly from infected patients are sometimes more resistant to antiviral agents than are viral strains bred in the laboratory.
Other investigations indicate that the antiviral effects of hypericin on murine cytomegalovirus (MCMV), Sindbus virus (SV), and HIV are enhanced by exposure to fluorescent light. Hypericin and to some degree, pseudohypericin, were effective against FV and HSV-1 when the viruses were first incubated with the compounds for one hour at 37 degrees C before mice were infected. Pre-incubation for one hour at 4 degrees C, however, produced no antiviral effects. The authors of this study (who are scientists at Lilly Research Laboratories) reported that hypericin and pseudohypericin were effective in vitro against enveloped viruses such as HSV and influenza when the cultures were pre-incubated with these agents at 37 degrees C. They also correctly showed that hypericin and its analogue inhibit DNA and RNA viruses, but not viruses which lack a lipid envelope. The Lilly researchers, who call AZT a preferred therapy for HIV, however, claim that single dose administration of hypericin is not efficacious. Human clinical trials are needed to evaluate the appropriate dose ranges at which hypericin is therapeutic but nontoxic, and to assess the differences, if any, between natural and synthetic hypericins. In animal studies, natural sources of hypericin (in combination with its analogue, pseudohypericin), showed greater antiviral activity that did synthetic hypericin. Preliminary findings thus far strongly indicate that the wide spectrum antiviral properties of hypericin, its experimental effectiveness at low concentrations, and its unconventional mechanisms of antiviral action make it a promising candidate for a new class of HIV therapies.
Mechanisms of action
Hypericin and pseudohypericin had no effect on purified reverse transcriptase alone. They did not alter levels of intracellular viral mRNA. Instead, hypericin lowers the number of mature viral particles without suppressing intracellular levels of viral mRNA. The concentrations of viral antigens on the cell surface were also unaffected by hypericin. These findings, as a whole, imply that the compounds interfere with viral assembly, budding, shedding or stability at the level of the cell membrane When hypericin was added to viral-infected cell cultures, red fluorescence appeared at localized areas on the lipid surface membrane.
Unlike nucleoside analogues, polycyclic diones such as hypericin have no effects on transcription, translation, or transport of viral proteins to the cell membrane. They are not directly active against reverse transcriptase even though reverse transcriptase activity was reduced in infected cells that had first been incubated with hypericin. Cells treated with hypericin form immature or abnormally assembled cores. This indicates that hypericin may block the processing of gag-encoded precursor polypeptides. Hypericin, whether in the intracellular medium or bounded to the membrane, is thought to lower the activity of reverse transcriptase by interfering with protein synthesis. (It is noteworthy that the antiviral effects of harmine, a photoactive alkaloid, involve disrupted kinase activity in enveloped RNA viruses.)
Viral particles are not formed when gag-related polyproteins fail to be cleaved or synthesized. Gag-related polyproteins, therefore, may play a decisive role in the virucidal actions of hypericin. Reverse transcriptase within the core of the assembled virus probably takes the form of an inactive enzyme or proenzyme. Mechanisms involving viral-encoded proteases or kinases might be required to activate reverse transcriptase. These mechanisms could transform the enzyme from a nonfunctional to a functional state. Both hypericin and pseudohypericin are thought to influence protease activity. In turn, altered protease activity could disrupt the cleavage or synthesis of gag-related polyproteins. As a result, immature viral cores would be formed. Alternatively, by selectively binding to viral polyproteins, hypericin could interfere with the gag and gag-pol polyproteins needed for viral assembly. Thus, hypericin could block the process whereby RNA packages encapsulated viral particles.
Some investigators, however, propose that hypericin lyses infectious virion by interacting directly with the viral envelope instead of disrupting gag-encoded precursor polyproteins or modifying other proteins. In any case, the antiviral properties of hypericin appear to involve its interactions with the cell membrane or cell surface recognition sites. Molecular modifications at or near the surface provide a model for rationally designing a new class of anti-HIV agents. Such therapies may be able to block HIV-encoded protease located in the gag-pol region. Importantly, drugs of this type would not be toxic like AZT and other agents whose pharmacological actions are based on direct inhibition of reverse transcriptase.
The aromatic, ringed structure encircled by six phenolic hydroxy groups seems critical to the antiviral activity of the hypericin molecule. Quinone groups, which often have antiviral properties, also exert photodynamic effects. Hypericin is thought to generate singlet oxygen. However, free radical quenchers can interfere with singlet oxygen reactions involving hypericin thereby reducing its antiviral properties.
Hypericin has a unique molecular structure in which one-half of the molecule is hydrophilic (water loving) while the other half is hydrophobic (water repelling). The top, bottom and side (non-polar) of the hypericin molecule which contains the methyl groups are hydrophobic. It is thought that the molecule might bond to the outer surface of the cell membrane. Presumably, the hydrophobic side would be immersed in fat Singlet oxygen, though less reactive than triplet oxygen, binds with two-electron targets, including, for example, the double bonds found in polyunsaturated fatty acids. The hydrophilic sides, in contrast, could hydrogen-bond to the aqueous media.
Discrepancies between in vivo findings from different studies on the antiretroviral effects of hypericin and pseudo-hypericin may be due partly to variations in light. However, differences in hypericin isolation methods and in the strains of mice used also could account for variable findings in several investigations. The antiviral effects of hypericin are largely but not completely, attributed to its photodynamic properties. In the presence of light, hypericin completely inhibited infection of cell cultures of equine infectious anemia virus (EIAV). On exposure to fluorescent light, hypericin inactivated MCMV, Sindbis virus (SV), and HIV-1. Both membrane virions and virus-infected cells were more strongly inactivated by visible light. (Polyacetylene phenylheptatriyine (PHY), a substance purified from the plant, Bidens pilosa, also shows antiviral activity against membrane-bound viruses such as MCMV. The antiviral effects, which involved interactions between PHY and membrane, occurred in the presence of long wave ultraviolet light). Significant advances in photobiological research have been made in recent years. New findings demonstrate clearly that photodynamic action accounts for the antiviral properties of several natural product derivatives, including hypericin.
Light is required for the photosensitization of hypericin. The compound absorbs light quanta and generates it in the form of singlet oxygen. In so doing, hypericin triggers the photo-oxidation of cellular components, including, for example, the photohemolysis of red blood cells. The underlying mechanism of photodynamic reactions is not fully understood. It is thought to involve interactions between oxygen and light as well as sensitizing pigment which binds to the cell membrane.
In photodynamic reactions mediated by hypericin, singlet oxygen serves as the main oxidant. Singlet oxygen has a strong affinity for pi electron-systems found in compounds such as polycyclic diones. The pi electrons, responsible for the photoactive properties of hypericin, absorb visible and ultraviolet light and then reemit it within the range of green and red light. The two hydroxy groups and the two methyl groups flanking each side of hypericin's eight ringed structure do not lie within the same plane. Instead, they repel each other, placing strain on the benzenoid structure. This causes the hypericin molecule to twist and become unstable. Hypothetically, the steric strain could increase the energy state of the pi electrons. This would allow them to form temporary bonds with singlet oxygen which, at a later point, could be released to disrupt mechanisms of viral replication. Pi electrons therefore, seem to play a major role in the antiviral activity of hypericin.
The "impressive light-mediated antiviral activities" of hypericin have been shown in several studies. Sindbus virus (SV), for example, was 99% inhibited in the presence of light. In the dark, however, the antiviral effects of hypericin were reduced by more than two orders of magnitude. On exposure to light (650-700nm.), hypericin undergoes type II photosensitization in which singlet oxygen and other reactive molecular species are produced. Though not as destructive as free radicals (which are generated in Type I photosensitization, singlet oxygen could damage viral membranes, thereby interfering with proteins and nucleic acids. Nonetheless, hypericin also has some degree of virucidal activity in the dark, though much less so than in light. It is thought that the antiviral effects produced in the absence of light take place through a different mode of action than light-mediated virucidal activity. Protein kinase C, for example, may represent an alternative target for hypericin's antiviral action in the absence of light.
One of the therapeutic advantages of hypericin is that it works by multiple steps. Hypericin is probably able to interrupt various phases in the replication of enveloped retroviruses. These stages include polyprotein cleavage and protein alterations as well as assembly, budding and shedding of viral components. The compound's disadvantages as an anti-HIV agent involve its potential toxicity when patients are exposed to sunlight. Also, it has been reported that in humans, hypericin is more effective in suppressing HSV-1 and HSV-2 than HIV. Future research is required to elucidate the mechanisms through which hypericin generates and reacts with singlet oxygen in triggering antiviral effects.
Clinical trials that were being conducted in early 1990's by Dr. Bihari in New York City recommend the following regimen. For the first two weeks, patients were given 10 mg of hypericin once a day for two weeks. During the second two weeks, the dosage alternates between 10 mg per day on the first day, 20 mg on the second day, 10 mg on the third day, and so forth. The ultimate dosage was given during the fifth and sixth weeks when patients were given 20 mg per day.
It has been proposed that beta-carotene, a known free radical quencher, be administered in combination with hypericin. Theoretically, this might reduce any toxic side-effects associated with hypericin's generation of free radicals. Some investigators, however, have warned that quenchers also may lessen the anti-viral properties of hypericin. The role of beta-carotene and other free-radical scavengers in hypericin therapy deserves further clarification.
Hypericin, a pigment molecule with photodynamic activity, has dramatic antiviral activity, especially in the presence of light. Like several other plant derived substances, hypericin only inhibits viruses with membranes. It has antiviral effects against a wide range of retroviruses, including HSV-1, HSV-2, (murine) CMV, and HIV-1. In contrast to nucleoside agents such as AZT, hypericin and its chemical relative, pseudohypericin, do not directly affect the activity of reverse transcriptase. Rather, these agents seem to disrupt various stages of viral replication, including assembly, budding, shedding and possibly protein synthesis, all of which depend on the integrity of the viral membrane.
Hypericin and related compounds, with their alternative targets for virucidal activity, comprise a new class of potential anti-HIV drugs. It is not yet known how effective hypericin will be in human AIDS. Preliminary findings, however, strongly suggest that this compound is one of the most promising, new anti-HIV prototype molecules currently under investigation.
Trans fats linked to increased endometriosis risk and omega-3-rich food linked to lower risk
Women whose diets are rich in foods containing Omega-3 oils might be less likely to develop endometriosis, while those whose diets are heavily laden with trans fats might be more likely to develop the debilitating condition, new research published today (Wednesday 24 March) suggests.
The study – which is the largest to have investigated the link between diet and endometriosis risk and the first prospective study to identify a modifiable risk factor for the condition – found that while the total amount of fat in the diet did not matter, the type of fat did. Women who ate the highest amount of long-chain Omega-3 fatty acids were 22% less likely to be diagnosed with endometriosis than those who ate the least and that those who ate the most trans fats had a 48% increased risk, compared with those who ate the least.
The findings from 70,709 American nurses followed for 12 years, published online in Europe's leading reproductive medicine journal Human Reproduction, not only suggest that diet may be important in the development of endometriosis, but they also provide more evidence that a low fat diet is not necessarily the healthiest and further bolster the case for eliminating trans fats from the food supply, said the study's leader, Dr Stacey Missmer, an assistant professor of obstetrics, gynaecology and reproductive biology at Brigham and Women's Hospital and Harvard Medical School in Boston, Massachusetts, USA.
'Millions of women worldwide suffer from endometriosis. Many women have been searching for something they can actually do for themselves, or their daughters, to reduce the risk of developing the disease, and these findings suggest that dietary changes may be something they can do. The results need to be confirmed by further research, but this study gives us a strong indication that we're on the right track in identifying food rich in Omega-3 oils as protective for endometriosis and trans fats as detrimental,' Dr Missmer added.
Endometriosis occurs when pieces of the womb lining, or endometrium, is found outside the womb. This tissue behaves in the same way as it does in the womb – growing during the menstrual cycle in response to oestrogen in anticipation of an egg being fertilized and shedding as blood when there's no pregnancy. However, when it grows outside the womb, it is trapped and cannot leave the body as menstruation. Some women experience no symptoms, but for many it is very incapacitating, causing severe pain. The tissue can also stick to other organs, sometimes leading to infertility. It afflicts about 10% of women. The cause is poorly understood and there is no cure. Symptoms are traditionally treated with pain medication, hormone drugs or surgery.
In the study, the researchers collected information from 1989 to 2001 on 70,709 women enrolled in the U.S. Nurses Health Study cohort. They used three food-frequency questionnaires spaced at four-year intervals to record the woman's usual dietary habits over the preceding year. They categorized consumption of the various types of dietary fat into five levels and related that information to later confirmed diagnoses of endometriosis. A total of 1,199 women were diagnosed with the disease by the end of the study. The results were adjusted to eliminate any influence on the findings from factors such as total calorie intake, body mass index, number of children borne and race.
Long-chain Omega-3 fatty acids are found mostly in oily fish. They have been linked to reduced heart disease risk. In the study, the highest contributor was mayonnaise and full-fat salad dressing, followed by fatty fish such as tuna, salmon and mackerel.
Trans fats are artificially produced through hydrogenation, which turns liquid vegetable oil into solid fat. Used in thousands of processed foods, from snacks to ready-meals, they have already been linked to increased heart disease risk. Some countries and municipalities have banned them. The major sources of trans fats in this study were fried restaurant foods, margarine and crackers.
'Women tend to go to the Internet in particular to look for something they can do. The majority of the dietary recommendations they find there are the ones prescribed for heart health, but until now, those had not been evaluated specifically for endometriosis,' Dr Missmer said. 'This gives them information that is more tailored and provides evidence for another disease where it is the type of fat in the diet, rather than the total amount, that is important.'
Besides confirming the finding, a next step could be to investigate whether dietary intervention that reduces trans fats and increases Omega-3 oils can alleviate symptoms in women who already have endometriosis, Dr Missmer added.
Source: European Society of Human Reproduction and Embryology
Indian spice may delay liver damage and cirrhosis
Curcumin, one of the principal components of the Indian spice turmeric, seems to delay the liver damage that eventually causes cirrhosis, suggests preliminary experimental research in the journal Gut.
Curcumin, which gives turmeric its bright yellow pigment, has long been used in Indian Ayurvedic medicine to treat a wide range of gastrointestinal disorders.
Previous research has indicated that it has anti-inflammatory and antioxidant properties which may be helpful in combating disease.
The research team wanted to find out if curcumin could delay the damage caused by progressive inflammatory conditions of the liver, including primary sclerosing cholangitis and primary biliary cirrhosis.
Both of these conditions, which can be sparked by genetic faults or autoimmune disease, cause the liver's plumbing system of bile ducts to become inflamed, scarred, and blocked. This leads to extensive tissue damage and irreversible and ultimately fatal liver cirrhosis.
The research team analyzed tissue and blood samples from mice with chronic liver inflammation before and after adding curcumin to their diet for a period of four and a period of eight weeks.
The results were compared with the equivalent samples from mice with the same condition, but not fed curcumin.
The findings showed that the curcumin diet significantly reduced bile duct blockage and curbed liver cell (hepatocyte) damage and scarring (fibrosis) by interfering with several chemical signalling pathways involved in the inflammatory process.
These effects were clear at both four and eight weeks. No such effects were seen in mice fed a normal diet.
The authors point out that current treatment for inflammatory liver disease involves ursodeoxycholic acid, the long term effects of which remain unclear. The other alternative is a liver transplant.
Curcumin is a natural product, they say, which seems to target several different parts of the inflammatory process, and as such, may therefore offer a very promising treatment in the future.
Source: British Medical Journal
Dietary Supplement Speeds Silver Cyclists
Taking arginine supplements can improve the cycling ability of over-50s. Researchers writing in BioMed Central's Journal of the International Society of Sports Nutrition tested a combination of the amino acid and an antioxidant in sixteen cyclists, finding that it enhanced their anaerobic threshold — the amount of work done before lactic acid begins to accumulate in the blood.
Zhaoping Li worked with a team of researchers from the University of California, Los Angeles, USA, to carry out the randomized controlled trial. She said, "The loss of exercise capacity with age often results in a reduction in physical fitness and more rapid senescence. A dietary supplement that increases exercise capacity might help to preserve physical fitness by optimizing performance and improving general health and well being in older people."
One way in which older people may reduce their exercise capacity revolves around the signaling molecule nitric oxide (NO), which is involved in many physiological processes, including those related to working out. NO production diminishes in quantity and availability as we age and is associated with an increased prevalence of other cardiovascular risk factors. In the body, NO is created from the amino acid arginine and is inactivated by oxygen free radicals. By supplementing diet with both the precursor and an anti-oxidant, the researchers hoped to support the NO system in the cyclists and thereby enhance performance.
Sixteen cyclists aged between 50 and 73 were randomly assigned to receive either the supplement or dummy placebo pills. After one week of study, the anaerobic threshold of the supplement group increased, while that of the control group did not significantly alter. This increase in anaerobic threshold was preserved at week three. According to Li, "We've demonstrated a 16.7% increase in anaerobic threshold. This indicates a potential role of arginine and antioxidant supplementation in improving exercise performance in elderly."
ScienceDaily (Mar. 23, 2010)


text: Each screen burning session often becomes a trial and error process that produces inconsistent results. What you need is a device that will work effectively each and every time you burn a screen. There is a simple solution to this problem. In the ASPA Screen Hold-Down "how-to" tutorial, we show how to make an effective, low cost screen hold-down that works perfectly each time you burn a screen. Get the complete plans, only $5.99.


text:
Meredy's blog about classic movies, classic stars, and Meredy.com updates.
July 15, 2012
Oscar-winning actress Celeste Holm dies at 95
Celeste Holm, a versatile, bright-eyed blonde who soared to Broadway fame in "Oklahoma!" and won an Oscar in "Gentleman's Agreement" but whose last years were filled with financial difficulty and estrangement from her sons, died Sunday, a relative said. She was 95.
Holm had been hospitalized about two weeks ago with dehydration. She asked her husband on Friday to bring her home and spent her final days with her husband, Frank Basile, and other relatives and close friends by her side, said Amy Phillips, a great-niece of Holm's.
Holm died around 3:30 a.m. at her longtime apartment on Central Park West, located in the same building where Robert De Niro lives and where a fire broke out last month, Phillips said.
"I think she wanted to be here, in her home, among her things, with people who loved her," she said.
In a career that spanned more than half a century, Holm played everyone from Ado Annie — the girl who just can't say no in "Oklahoma!"— to a worldly theatrical agent in the 1991 comedy "I Hate Hamlet" to guest star turns on TV shows such as "Fantasy Island" and "Love Boat II" to Bette Davis' best friend in "All About Eve."
She won the Academy Award in 1947 for best supporting actress for her performance in "Gentleman's Agreement" and received Oscar nominations for "Come to the Stable" (1949) and "All About Eve" (1950).
Holm was also known for her untiring charity work — at one time she served on nine boards — and was a board member emeritus of the National Mental Health Association.
She was once president of the Creative Arts Rehabilitation Center, which treats emotionally disturbed people using arts therapies. Over the years, she raised $20,000 for UNICEF by charging 50 cents apiece for autographs.
President Ronald Reagan appointed her to a six-year term on the National Council on the Arts in 1982. In New York, she was active in the Save the Theatres Committee and was once arrested during a vigorous protest against the demolition of several theaters.
But late in her life she was in a bitter, multi-year family legal battle that pitted her two sons against her and her fifth husband — former waiter Basile, whom she married in 2004 and was more than 45 years her junior. The court fight over investments and inheritance wiped away much of her savings and left her dependent on Social Security. The actress and her sons no longer spoke, and she was sued for overdue maintenance and legal fees on her Manhattan apartment.
The future Broadway star was born in New York on April 29, 1917, the daughter of Norwegian-born Theodore Holm, who worked for the American branch of Lloyd's of London, and Jean Parke Holm, a painter and writer.
She was smitten by the theater as a 3-year-old when her grandmother took her to see ballerina Anna Pavlova. "There she was, being tossed in midair, caught, no mistakes, no falls. She never knew what an impression she made," Holm recalled years later.
She attended 14 schools growing up, including the Lycee Victor Duryui in Paris when her mother was there for an exhibition of her paintings. She studied ballet for 10 years.
Her first Broadway success came in 1939 in the cast of William Saroyan's "The Time of Your Life." But it was her creation of the role of man-crazy Ado Annie Carnes in the Richard Rodgers and Oscar Hammerstein II's musical "Oklahoma!" in 1943 that really impressed the critics.
She only auditioned for the role because of World War II, she said years later. "There was a need for entertainers in Army camps and hospitals. The only way you could do that was if you were singing in something."
Holm was hired by La Vie Parisienne, and later by the Persian Room at the Plaza Hotel to sing to their late-night supper club audiences after the "Oklahoma!" curtain fell.
The slender, blue-eyed blonde moved west to pursue a film career. "Hollywood is a good place to learn how to eat a salad without smearing your lipstick," she would say.
"Oscar Hammerstein told me, 'You won't like it,'" and he was right, she said. Hollywood "was just too artificial. The values are entirely different. That
balmy climate is so deceptive." She returned to New York after several years.
Her well-known films included "The Tender Trap" and "High Society" but others were less memorable. "I made two movies I've never even seen," she told an interviewer in 1991.
She attributed her drive to do charity work to her grandparents and parents who "were always volunteers in every direction."
She said she learned first-hand the power of empathy in 1943 when she performed in a ward of mental patients and got a big smile from one man she learned later had been uncommunicative for six months.
"I suddenly realized with a great sense of impact how valuable we are to each other," she said.
In 1979, she was knighted by King Olav of Norway.
In her early 70s, an interviewer asked if she had ever thought of retiring. "No. What for?" she replied. "If people retired, we wouldn't have had Laurence Olivier, Ralph Richardson, John Gielgud ... I think it's very important to hang on as long as we can."
In the 1990s, Holm and Gerald McRainey starred in the CBS's "Promised Land," a spinoff of "Touched by an Angel." In 1995, she joined such stars as Tony Randall and Jerry Stiller to lobby for state funding for the arts in Albany, N.Y. Her last big screen role was as Brendan Fraser's grandmother in the romance "Still Breathing."
Holm was married five times and is survived by two sons and three grandchildren. Her marriage in 1938 to director Ralph Nelson lasted a year but produced a son, Theodor Holm Nelson. In 1940, she married Francis Davies, an English auditor. In 1946, she married airline public relations executive A. Schuyler Dunning and they had a son, Daniel Dunning.
During her fourth marriage, to actor Robert Wesley Addy, whom she married in 1966, the two appeared together on stage when they could. In the mid-1960s, when neither had a project going, they put together a two-person show called "Interplay — An Evening of Theater-in-Concert" that toured the United States and was sent abroad by the State Department. Addy died in 1996.
Funeral arrangements for Holm were incomplete. The family is asking that any memorial donations be made to UNICEF, Arts Horizons or The Lillian Booth Actors Home of The Actors Fund in Englewood, N.J.
Posted by Meredy at 7:32:00 PM No comments:
July 09, 2012
Ernest Borgnine dies at 95
The stocky, gap-toothed Connecticut native won an Academy Award for his portrayal of a lonely Bronx butcher looking for love in the 1955 drama 'Marty.' He also starred in the popular TV show 'McHale's Navy.'
Ernest Borgnine seemed born to play the heavy when he burst onto the Hollywood scene as "Fatso" Judson, a sadistic stockade sergeant who viciously beats a private to death in the 1953 movie "From Here to Eternity."
But two years later came the title role in "Marty," where the stocky, gap-toothed Borgnine defied typecasting and earned recognition as a versatile actor by inhabiting the part of a lonely Bronx butcher looking for love.
He went on to a prolific seven-decade career in film and television, moving easily from scoundrels and serious portrayals to a comedic role on the 1960s TV sitcom "McHale's Navy" and a spate of grandfatherly parts.
Borgnine, who won an Academy Award for his performance in "Marty," died Sunday of apparent kidney failure at Cedars-Sinai Medical Center in Los Angeles, said his longtime publicist, Harry Flynn. He was 95.
The role opposite Frank Sinatra in "From Here to Eternity," based on James Jones' acclaimed novel depicting Army life in Hawaii before the attack on Pearl Harbor, moved Borgnine into the top echelon of movie villains in films such as "Vera Cruz" and "Bad Day at Black Rock."
He left expectations behind in "Marty," the 1955 film version of Paddy Chayefsky's original TV play about a sensitive Italian American bachelor butcher who longs for more than simply hanging out with his pals on Saturday night.
"Well, waddaya feel like doing tonight?" Marty's best friend, Angie, played by Joe Mantell, asks in the movie's often-quoted exchange.
"I don't know, Ang', wadda you feel like doing?" Marty replies.
Borgnine's sensitive portrayal of the self-described "fat ugly man" not only earned him an Oscar for best actor, but the movie also won Academy Awards for Chayefsky and director Delbert Mann, as well as the best picture Oscar.
In a film career that began in 1951, Borgnine appeared in more than 115 movies, including "Johnny Guitar," "Demetrius and the Gladiators," "The Flight of the Phoenix," "The Oscar," "The Dirty Dozen,""The Wild Bunch,""Willard," "The Poseidon Adventure" and "Emperor of the North."
From 1962 to 1966, he played the title role in the ABC sitcom "McHale's Navy." As the regulation-breaking commander of a PT boat in the South Pacific during World War II, Borgnine was pitted against the constantly frustrated Capt. Binghamton (played by Joe Flynn). Tim Conway played McHale's bumbling sidekick, Ensign Charles Parker.
Born Ermes Effron Borgnino in Hamden, Conn., on Jan. 24, 1917, Borgnine was the son of Italian immigrants. His parents separated when he was 2, and his mother took him to live in Italy, returning after a few years.
Borgnine graduated from New Haven High School in 1935, then worked a few weeks as a vegetable truck driver before enlisting in the Navy as an apprentice seaman. He was discharged two months before the attack on Pearl Harbor and promptly reenlisted. He spent the war as a gunner's mate on a destroyer.
After his discharge, Borgnine returned home, unsure of what he was going to do.
Finally, his mother suggested he give acting a shot. After all, she told him, "You're always making a fool of yourself in front of people."
After six months of study at the Randall School of Dramatic Art in Hartford, Conn., on the GI Bill, Borgnine got a job at the Barter Theatre in Abingdon, Va., working behind the scenes before finally landing a $30-a-week acting spot in the theater's road company.
"We kept 14 shows in our heads all the time," he told Hollywood columnist Hedda Hopper in 1956. "We'd go from 'John Loves Mary' to 'Much Ado About Nothing' — what training! Dramatic school is OK, but the road is where you learn."
He continued his acting apprenticeship over the next four years, including making his Broadway debut playing the hospital attendant in"Harvey."
More stage work followed, supplemented by television appearances, including playing a villain on the science fiction series "Captain Video and His Video Rangers."
Borgnine made his motion picture debut in 1951, appearing in three films: "China Corsair," "The Whistle at Eaton Falls" and "The Mob." But he was unemployed in New York when the call came to play his next film role: Fatso Judson in "From Here to Eternity."
Borgnine made a convincingly menacing Fatso — so much so that when young Frank Sinatra Jr. saw the movie for the first time, Borgnine later told The Times, "He looked at it and said, 'Dad, when I meet that man, I am going to kill him.' And his father said, 'No. When you meet that man, you put your arms around him and kiss him. He helped me win an Academy Award!' "
Borgnine was on location in Lone Pine, Calif., playing another menacing heavy, this time in "Bad Day at Black Rock," when director Mann and writer Chayefsky flew up to have him read for the lead in "Marty."
As Borgnine recalled during a panel discussion at the Lone Pine Film Festival in 1999, he met with Mann and Chayefsky in his hotel room.
"The very first thing when we started reading, Paddy Chayefsky said, 'Hold it! Hold it!' I said, 'What's the matter?' He said, 'You're doing it with a western twang.' 'OK,' I said, 'wait a minute.' I threw off my hat, kicked off my boots and I went at it.
"Paddy was reading all the other parts and Delbert was stretched across my bed, listening, and we came to the part where my mother says, 'Put on your blue suit or your gray suit and go down to the dance hall; there are a lot of tomatoes there.' And I said, 'Mom, you don't understand. I'm just an ugly, ugly man,' and I turned away and tears were coming out.
"And I looked back and Paddy Chayefsky had tears in his eyes and Delbert was wiping tears from his face, and inwardly I said, 'I got it!'"
"Marty" proved to be both an artistic and commercial success.
Life magazine called Borgnine's characterization of the lonely butcher who falls in love with an equally plain and lonely schoolteacher (played by Betsy Blair) "one of the most successful pieces of movie casting so far this year."
New York Times film critic Bosley Crowther wrote that Borgnine's Oscar-winning performance was "a beautiful blend of the crude and the strangely gentle and sensitive in a monosyllabic man."
In the wake of "Marty," Borgnine played an Amish farmer in "Violent Saturday," a prizefight promoter in "The Square Jungle," a rancher in "Jubal" and a Bronx taxi driver (opposite Bette Davis) in "The Catered Affair."
But he was soon back in front of the cameras playing another heavy, this time the villainous Norse chief in "The Vikings," a 1958 film co-starring Kirk Douglas and Tony Curtis.
"After 'From Here to Eternity,' I decided to steer away from heavies, but here I'm playing one again," he told The Times at the time.
"I made the original decision after some young Bronx characters almost took me apart. 'You're the guy that killed Sinatra,' a group yelled at me one day in New York, and it looked bad until I spoke soothingly to them in Italian — a language they understood. 'Fellows, it was just a picture,' I said. They were so intrigued that I spoke Italian, they let me go."
Borgnine closed out the '60s with a memorable role in Sam Peckinpah's bloody 1969 western "The Wild Bunch" and later made numerous television guest shots as well as appearances in TV movies and miniseries.
In the short-lived 1970 series "Future Cop," he starred with John Amos as veteran policemen whose new partner is a biosynthetic computerized android.
And he played Jan-Michael Vincent's older war buddy, Dominic Santini, on "Airwolf," a mid-1980s CBS adventure series about a high-tech attack helicopter.
In 1995, Borgnine was back in series television playing a friendly, pasta-loving doorman on "The Single Guy," which ran for two seasons on NBC. He also was the longtime voice of Mermaid Man on the animated TV series "SpongeBob SquarePants."
Off-screen, Borgnine has been described as soft-spoken and affable — a simple, unassuming, average man.
Beginning in the late 1980s, when he wasn't working, he traveled the country in a custom-made bus dubbed the Sunbum. In 2001, at age 84, he had just completed his latest trip to Alaska.
"I find it terribly relaxing," he told The Times in 1996. "It's like driving a big car. You see everything. The minute you get out of the cities, it's wonderful. You become part of America."
When Borgnine received the Screen Actors Guild Life Achievement Award in 2011, his career in front of the camera had spanned six decades. And at age 94, the venerable actor was still going strong.
As he said in 2008 when he received a Golden Globe nomination for his performance as a retired song-and-dance man in the TV-movie "A Grandpa for Christmas": "You die on the vine if you just sit down in a chair and get old. The idea is to get up out of the chair and go out there and hustle."
Borgnine's final role came earlier this year in "The Man Who Shook the Hand of Vicente Fernandez," as a retired radio DJ with an unfulfilled dream of stardom who winds up in a nursing home staffed by Latin American immigrants.
Borgnine was married five times, including to actress Katy Jurado from 1959 to 1964, and briefly to Broadway musical star Ethel Merman in 1964.
In 1973 he married his Norwegian-born fifth wife, Tova, who became head of her own cosmetics company.
Besides his wife, he is survived by his children Nancee, Cristofer and Sharon Borgnine and David Johnson; six grandchildren; and a sister, Evelyn Velardi.
Services will be private.
Posted by Meredy at 2:01:00 PM No comments:
Subscribe to: Posts (Atom)


text:
LUCIR-K本店<ルシルケイ> welcomes you and presents its collection of TAG Heuer watches in 静岡県. Choose the watch that suits you most from the broad range of sports and elegant watches. In our TAG Heuer store, you will find a specialized adviser who will answer your questions and help you in your choice.
Looking for an elegant watch in 静岡県?
TAG Heuer is in 静岡県 to present its collection of prestige watches in a setting inspired by the spirit of the brand: LUCIR-K本店<ルシルケイ>
Trust our store and let yourself be seduced by a precision Swiss timepiece whether you are looking for a men or women's luxury watch.


text:
Le Skylab (2011)
Julie Delpy is a French-American filmmaker who has weaved between roles in acclaimed films, most notably Richard Linklater's (soon to be) Before… trilogy, and making accomplished films herself. As a director she is best known for 2 Days in Paris, a refreshing and genuinely funny romantic comedy which managed to deftly sidestep cliche, as well as follow-up 2 Days in New York. This, her fourth feature, is set in 1979, and centres upon a summer holiday family get together in Brittany, disrupted by the falling to earth of the space station which gives the film it's name.
Delpy drew upon her own childhood experiences during writing, and even admitted in an interview with the Guardian that "a lot of the lines in the film are literally out of my memory", with a number of characters inspired in some way by family members. The filmmaker stars as Anna, mother of Albertine, the nine year old obsessed with the satellite and unable to understand her elder's relative disregard of the news story unfolding in their direct vicinity.
Similarly to both 2 Days instalments, Delpy's dialogue is natural and well-crafted, her characters discussing age, sex and politics with poignancy and unforced, subtle humour. Politics, however, is much more an explicit presence in Le Skylab than her other features. The adults of the group, reluctant at first to discuss the unfolding news story at first lest the children begin to panic, soon begin to speculate wildly, to results both humorous and unnerving.
There's a tension which creeps into the extended family's interactions and results in many purely dramatic scenes delivered convincingly by the strong cast. The filmmaker's father, Albert, plays Herbert, a man struggling from the onset of mental illness and mounting depression, and proves a compelling screen presence. Elsewhere, scenes exploring early-teenage sexuality are well-judged. Delpy handles these darker themes with confidence and dexterity, and Le Skylab is an engrossing film, elegant yet unshowy, and a strong addition to the career of a highly talented filmmaker.
Take a look our coverage of the festival's Creating Your Own Funny World workshop, and A Liar's Autobiography.


text:
Your child's learning style: Part 2
How does your child learn best? As a parent, you are your child's first teacher. Learn more about how to help kinesthetic learners discover their strengths and have successful learning experiences.
Does your preschooler love to take things apart, to participate in sports and to move, rather than sitting still and studying? Are they well-coordinated and agile? If you answered yes, your child is probably a kinesthetic learner.
According to University Illinois Extension, children who are kinesthetic learners learn best by using their bodies and their hands. They love to move and get physically involved in their learning. When talking about preschoolers, according to Piaget's theories, the majority of preschool children are kinesthetic learners since many are still within the sensorimotor phase of development.
As your young child's first and most important teacher, it is important that parent's help their child embrace their kinesthetic learning style. Use it as a tool to for them to become a successful learner in their early years of school. As a kinesthetic learner, your child needs opportunities to manipulate and experiment with hands-on tools.
Michigan State University Extension recommends the following kinesthetic learning tools to help your young kinesthetic learner learn basic skills, such as counting and writing:
- Hula hoops
- Large yoyos
- Large colored markers
- Frisbees
- Play dough
- Sand
- Puzzles
- Stickers
Remember that kinesthetic learners are not fidgety and antsy, but rather learn by doing. The goal for you as parents is to try to maximize your child's kinesthetic learning strength. Remember your child needs your helping hand to lead them in learning, as well as opportunities to move their bodies within their environment.
Learn more about children's learning styles in Part 1 of this series.


text:
Create Safe Environments & Operations
Fournier, Robson & Associates provides services to new and existing sport and recreation center operators. These facilities include indoor and outdoor sports complexes, community recreation centers, arenas, and sports tourism destinations. Our capabilities encompass planning services for new centers such as design consultation, program recommendations and management expertise.
We also provide services for new or existing facilities such as development of operations manuals, management and staff training, and risk evaluation services for creating safe physical environments and safe program operations.


text:
Join us as we explore Park City's culinary scene. We'll tell you where you should eat, what you should order and what's new. Let's dish.
Dishing is a biannual print magazine focusing on the culinary scene in and around Park City, offering residents and visitors entertaining information about restaurants, food trends and chefs in the region. The first Dishing magazine was published in Jackson Hole in 2011 and has quickly grown into THE source for food information and restaurant options. It's a unique combination of food magazine and dining guide, which makes it a resource for locals, visitors and the hospitality industry.
Everyone eats out, so our audience is also that broad. Dishing is designed to reach a wide-ranging reader, from the well-traveled and well-fed foodie to a kitchen novice who eats out for convenience. The readership is comprised of a mix of locals and tourists of all ages and income brackets. Locals and tourists use it to keep current about what is going on in the restaurant scene. Tourists come to Park City for experiences and they use Dishing as their guide to the plan the most memorable culinary expediences. Concierge services use Dishing to direct others to the best spots to eat around town. Our easy, approachable content and mouthwatering photographs invite readers to savor the publication for months. It's designed to stay on the coffee table for six months until the next comes out.


text:
Soft suede is lined with a warm, shearling lining in the ultimate slip-on-and-go style. Read More »
BEARPAW Women's Emma Short Boot,Hickory/Champagne,7 M US
April 26, 2016
April 26, 2016
April 25, 2016
This tall women's boot by BearPaw offers a style that's well paired with denim, a casual skirt, or country dress, with a ruggedly comfortable design ideal for kicking around town. Read More »
April 25, 2016
The Lauren is sure to be a fan favorite! Featuring a triple toggle closure, it Read More »
April 18, 2016
February 13, 2016
January 25, 2016
November 16, 2015
Relax your paws with these comfortable womens suede boots with shearling sheepskin lining from BearPaw. This boot features a leather upper, wool lining, sheepskin insole, and a manmade sole. Read More »
August 8, 2015


text:
I decided to go to Service Canada last week to begin the legalized change of my French slave name to a West African name. I searched long and hard and found new African names for me and my 2 year old son who is of African-Iranian descent.
I chose Nomolanga Achieng Eksenwe for myself because Nomolanga Achieng because it is Zulu for "sunny" and I'm an optimistic, cheery person born in the middle of summer. I also chose it because "Achieng" which means "sunlit" is reminiscent of the warm, chocolate brown skin I have. I chose the last name Eksenwe, which is a well known last name.
My son's new name Chilongola means "firstborn son" and his middle name Masego means "blessings". I feel our African names are not just a powerful way of reclaiming our African identity that was stolen away, but of defying the racist social control that exists today. It is a constant reminder of our Blackness, our heritage and history. Not just for ourselves, but for everyone we encounter from colleagues, school peers and strangers.
I have rid ourselves of the continuity of the Blanchette, Riviere and Dangleben slaveholding families that held dominance over my family for over a century by their French names. Therefore, what we achieve will be Black excellency, not that of our oppressors. They cannot bind us with their stamp no more.


text:
Ribbed housecoat, anonymous, c. 1930 - c. 1939
This heavy ribbed silk robe would have been worn at home as a dressing gown or for receiving guests. This was not unusual in the 1930s, when the distinction between garments for private and public eroded. To some extent this trend can be compared to the fashion for banyans in the 17th and 18th century.


text:
An overview of the news related to significant events in the field of competition in Russia and abroad is presented in the bulletin prepared by the Directorate for Competition Policy of the Analytical Center. The experts focus on competition between air carriers.
The seventh report of the Federal Antimonopoly Service notes that the current problem in this field is the competition in the markets of jet fuel and fueling services for aircraft. However, according to the experts of the Analytical Center, the high cost of aviation fuel is not the only problem in passenger air travel. In their opinion, the limited access by the carriers to necessary airport infrastructure and restricted access of foreign carriers to the Russian air transport market is also a problem.
Thus, the experts recognize that competition is not always a guarantee for the industry's development. For example, in the regional traffic segment, it may even be harmful, at least in the first stages of the market's formation.
More details can be found in the bulletin "Problems of Competition in the Airline Industry".


text:
Allok Video to DVD Burner is an easy and professional DVD maker software that lets you convert all favorite movies to DVD movies and burning it onto DVD Disc, and then watch them on home DVD Player ,car DVD Player or any other portable DVD Player.
It supports converting AVI, DivX ,Xvid, MPEG, VCD, WMV, ASF, MOV, RM, RMVB, 3GP, MP4, FLV, MKV video clips to DVD movies, with fast speed and hight quality.
It supports different output DVD quality, so you even can burn 7 hours movies to one DVD disc. All encoders/codec are built-in and any supported conversion can be done once you downloading the software .


text: Founded by the distinguished bandmaster Eddie Green, the University of Houston Wind Ensemble of the Moores School of Music has become recognised as one of the foremost university ensembles in the United States today. The ensemble is dedicated to exploring the full breadth of the wind-ensemble literature, from the canonic wind repertoire to exciting new and unexplored works. The International Grainger Society selected the Houston Wind Ensemble to record a four-volume series of compact discs featuring works by the Australian-American visionary. One of these recordings was named "compact disc of the year," by Stereophile. Two of the wind ensemble's other recordings have been nominated for GRAMMY® awards, making them the first college wind ensemble to earn a GRAMMY® nomination. The Moores School of Music's commitment to academic excellence and the highest performance standards has earned it a place in the forefront of music schools today. Undergraduate and graduate degrees through the doctoral level are offered in theory, performance, composition, music history, pedagogy, conducting, and music education. Through the excellence of its curriculum, the distinction of its faculty, the success of its graduates, and its alliances with the city's esteemed arts organizations, the Houston Symphony, Houston Grand Opera, and the Society for the Performing Arts, the school enjoys a reputation that attracts students from throughout the United States, Canada, Europe, Mexico, South and Central America, and the Far East.


text:
The right bag can make or break the overall look you're going for. Do you match your bag with your shoes? Or do you contrast your
Has having the time displayed on our phones made the humble watch disappear from our wish list? No the sale of watches is still going strong
When I first started experimenting with makeup in my youth I had absolutely no idea how to apply it and the trials in my bedroom
When out running or training in the gym its important afterward you don't get cold...yes whilst you're pounding the streets on that summer evening or
They say wearing black is slimming and many feel that wearing black is elegant and makes them feel more confident. Personal I NEVER wear black as


text:
The Republic of Armenia is considered a small landlocked country located in the Caucasian region of Eurasia. The landscape diversity in Armenia and the peculiarity of its terrain represent critical factors for the formation and evolution of the flora and fauna in the country. The biodiversity in Armenia includes more than 200 edible plant species, 40 edible fungi species, more than 1000 fodder plants, 350 species of honey plants, 350 ether bearing plants, 120 dye plants, 100 vitamin producing plants and 60 rubber producing plants; around 10% of the flora in Armenia are considered to have medical properties... More »
Biodiversity loss has been most rapid in the last century as a result of the development of industry, agriculture, urbanization, energy and the intensive exploitation of forests, grasslands and other ecosystems. The main threats to biodiversity are directly or indirectly connected with anthropogenic forces and include habitat change, overexploitation, pollution through wastewaters and mineral fertilizers, overgrazing, plowing and illegal logging, tourism development, introduced alien species, climate change and poor irrigation systems that cause salinization and soil erosion... More »
The main goal of Armenia's NBSAP is to ensure the conservation, sustainable use and regeneration of the landscapes and biological diversity of the Republic of Armenia for sustainable human development. As part of the NBSAP, 13 tasks have been proposed with a total of 245 actions and measures. Each of these actions and measures is relatively prioritized... More »
Specially protected areas serve as a means to effectively preserve biodiversity in Armenia. Their total area comprises 379,187 hectares or 12.7% of the country's total area (or 7% of the total area if the surface of Lake Sevan is excluded). Fifty-four percent of the specially protected areas consists of forest ecosystems; 70% of the country's flora and fauna is protected in specially protected areas... More »
Three main strategic documents have been developed in Armenia which are directly connected to biodiversity conservation, namely: Second National Environmental Action Programme of the Republic of Armenia (approved by the Government of Armenia in 2008, containing priorities for biodiversity conservation that are directly related to the 2010 Biodiversity Target); Biodiversity Strategy and Action Plan of Armenia (1999); Strategy for Developing Specially Protected Areas and National Action Plan of Armenia (2002)... More »
Multiple tools exist for monitoring and reviewing implementation. Within the framework of the Natural Resource Management and Poverty Reduction Project, the mapping of national parks, inventorying of biodiversity components and introduction of a system for biodiversity monitoring have been carried out.


text: Reports indicate that a supertanker and a container ship collided in Singapore waters southeast of St John's Island. But the incident did not result in any oil pollution or casualty, says the Maritime and Port Authority of Singapore. It has deployed an anti-pollution craft to monitor the situation and is investigating the incident. MPA says Greece-registered supertanker, Astro Luna, was heading west in the Singapore Strait when it collided with Panama-registered container ship, YM Earth. At the time of the collision, Astro Luna was not carrying any oil. YM Earth, which was loaded with containers, was then approaching the Eastern Pilot Boarding Ground 'A' enroute for the Tanjong Pagar terminal. Source: Channel News Asia


text:
You don't have to be super-fit to run the Lincoln 10k and you don't even have to take it too seriously – after all, last year a knight in full armour and a playful team of a 'doctor', 'nurse' and 'surgeon' were among those running in aid of the Lincs & Notts Air Ambulance charity.
And, the oldest participant was an octogenarian – showing that anyone really can take part.
Despite being dispatched to some of the most serious 999 calls in Lincolnshire and Nottinghamshire, the charity is not Government-funded and relies totally on the support of the community we serve to raise this money. Therefore, every penny raised by their fabulous fundraisers helps to save lives.
Community Fundraisers Faye Nam (Lincolnshire) and Karen Carter (Nottinghamshire) said: "This year we will increase the hours that we fly meaning we will soon be operational for 24 hours a day. We need to raise £4m a year to make this possible. That is why we are appealing to more people than ever before to run their local 10k in aid of our life-saving Charity.
"It is a great way to raise money in a fun way while getting fit at the same time. We look forward to hearing from anyone who would like to run for us and take advantage of the free entry this year."
The Lincoln 10k will take place on March 18, and the Nottingham 10k on August 12. If you sign up to either of these events through the Lincs & Notts Air Ambulance, it is free to enter. All they ask is that you pledge to raise a minimum of £75 in sponsorship which will help to support their live-saving work.
The charity will supply you with sponsor form and posters so that you can let people know that you are running for us and gain as much sponsorship as possible.
To sign up, either as an individual or as a team, visit www.ambucopter.org.uk/what-is-your-2018-challenge/
If you have already signed up, don't worry - you can still raise money for the Lincs & Notts Air Ambulance. Simply email firstname.lastname@example.com or call 01522 548469 to request a sponsor form.
Lincs & Notts Air Ambulance also still has charity places available for this year's Great North Run, taking place on September 9. If you would like to sign up for this half marathon (13.1 miles), email firstname.lastname@example.com or call 01522 548469.