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Resort Report
- Talking Taino: Obeah and Zombies September 1, 2005 The African Connection By Dr. Bill Keegan and Dr. Betsy Carlson Whenever we visit the Turks & Caicos we try to get together with our old friend, Chuck Hesse (Caicos Conch Farm). And every time we see Chuck he promotes his belief that Africans were living in the Islands prior to the arrival of the Spanish. The case ... Read more about this post
- Getting Out of the Loop: Windmills Plantation on Salt Cay September 1, 2005 By Michelle Belanger-McNair ~ Photos by Chris Sanders Cell phones are forbidden; shoes are optional. The bar is always open. Check your worries at the door. This is the Windmills Plantation on Salt Cay. Salt Cay is a laid back, out-of-the-loop-of-life, island in the sun. The Windmills Plantation takes you even further from the frenetic pace of ... Read more about this post
- A Perfect Hue of Blue: St. Charles Condominiums, North Caicos September 1, 2005 By Kathy Borsuk When Phillip Misick was brainstorming for a name for North Caicos' first condominium resort development, it was his father Charles that came to mind. "My dad was a founding member of the Turks & Caicos Islands Progressive National Party (PNP), served for over 15 years in the Legislative Council and was committed to ... Read more about this post
- Four-Legged Visitors September 1, 2005 Traveling to TCI with your pet Story & Photos By Michele Belanger-McNair My husband has packing nightmares before we leave on our annual two month trip to Salt Cay. I thought, "Why not add to those nightmares by taking the dog?" Fortunately, taking Marley to Salt Cay, a small, somewhat isolated part of the Turks Islands, was ... Read more about this post
- An Unexpected Visitor September 1, 2005 By Brian Riggs, Curator, National Environmental Centre When Lisa Wandres, who lives in Grand Turk, took her dog Scooter down to South Creek for a walk on Saturday morning, April 23, she expected to see the usual things you can see there: birds, bonefish, crabs and mosquitoes. It's a quiet spot, the South Creek, and quite ... Read more about this post
- The Meaning of Sanctuary: It's for the Birds September 1, 2005 Story and Photos By Kathleen McNary Wood There are no places left on earth that are not altered by man and his activities. As time ebbs and flows, a tide of change has swept across the planet. Gone are the days when man battled against nature only to maintain a fragile foothold on existence. We are ... Read more about this post
- If Windows Could Speak… June 1, 2005 Photos By Michele Belanger-McNair If only windows could tell what they have seen and heard. I was looking up at a bedroom window at the White House on Salt Cay one day, shooting pictures of this venerable old home and the now fallen Treasury office next door. As I stood there, I thought: How many women have ... Read more about this post
- Right Place, Right Time June 1, 2005 The Royal Reef Resort By Kathy Borsuk~ Renderings by QR Imaging North Caicos beach fronting Royal Reef Resort North Caicos beach fronting Royal Reef ResortEvery so often, an opportunity appears that is too good to pass up. That's the way Fred Paatz and Mark Hall felt when they first saw the beach just north of Sandy Point, North ... Read more about this post
- Knowledge is Power June 1, 2005 By Brian Riggs, Curator, National Environmental Centre In late 2001, the Turks & Caicos Islands Government signed an important and far reaching document. It was called the Environmental Charter. That document outlined our country's commitment to the environment and conservation efforts on behalf of the people of the Islands. The very first guiding principle recognized that ... Read more about this post
- Talking Taino: If You Like Pina Coladas… June 1, 2005 By Dr. Betsy Carlson and Dr. Bill Keegan Pineapple and coconut are an interesting combination. While the former comes from the Americas, the latter was introduced from Southeast Asia (via the Canary Islands) by the Spanish. The Spanish believed that coconuts had "the most palatable taste of all things one can find on earth." They also ... Read more about this post
- Time For Safekeeping June 1, 2005 Marine Turtle Project Story and Photos by Peter Richardson, Marine Conservation Society Turks & Caicos Islanders have eaten turtles for centuries. Archaeological digs around the Islands have revealed that Taino settlers were heavily dependent on turtle meat and eggs long before these Islands were "discovered" by Europeans. These later colonists continued to exploit the rich marine turtle ... Read more about this post
- Searching For Sun June 1, 2005 By Steve Rennie It's been more than one year since Conservative Member of Parliament Peter Goldring introduced a motion in the Canadian House of Commons calling for discussions to explore the possibility of a union between the Turks & Caicos Islands and Canada. While there has been some progress made, the two nations are still half ... Read more about this post
- The Butterflies of The Turks and Caicos Islands April 1, 2005 Story and Photos by Richard Ground Over 40 species of butterfly have been recorded in the Turks & Caicos Islands. They range from the large and showy Bahaman Swallowtail (Heraclides andraemon) down to the tiny Pygmy Blue (Brephidium exilis). While most of the species range throughout the Islands, some are quite local in their distribution. The Swallowtail, ... Read more about this post
- Talking Taino: Starry, Starry Night April 1, 2005 By Dr. Bill Keegan and Dr. Betsy Carlson Jacques Derrida is dead. He died on October 9, 2004 at the age of 74. Derrida was a French philosopher who recognized the importance of language in shaping our perception of the world around us. He pioneered a field of critical theory called deconstructionism. The approach argues that ... Read more about this post
- Mandalay on Grace Bay April 1, 2005 Caribasian Resort & Residences By Kathy Borsuk~ Artwork by Kevin Melbourne Many travelers find themselves captivated by the mysterious charms of the East. Its ancient blend of energy, peace and wisdom grows ever more compelling as the Western world becomes increasingly chaotic. As well, the standards of its high-end hospitality industry are unparalleled. With this in mind, ... Read more about this post
What's Inside The Latest Edition?
On the Cover
Agile LeVin grew up in the Turks & Caicos Islands and has a keen eye for capturing the country's natural beauty. This aerial shot depicts kayakers exploring Mangrove Cay, a very well-known kayaking and paddle boarding location near Leeward on Providenciales, part of the Princess Alexandra Nature Reserve. To see more of Agile's work, go to visittci.com.


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It can be said that good procurement is at the heart of good government. Proper conduct of public procurement entails proper stewardship by each level of government of the public funds entrusted to it, whether raised through taxes levied by that level of government directly, or obtained by way of a transfer payment from some other level of government.
Stewardship, in the public procurement context, means the careful and responsible management of public funds, not only through the safeguarding of taxpayers' money, but also through the promotion of the public interest. Without government, the responsibility for proper stewardship is pervasive. It is not simply the responsibility of elected politicians and senior members of the public service.
Important as the operational and control aspects of municipal procurement may be, the strategic aspect of such activity are of even more importance. In dealing with the subject of municipal procurement, I have always maintained this continuing theme. It is a fact that municipal procurement needs to become more strategic in design, more deliberative in execution, and more critical in its approach and implementation.
When I started in the procurement field over 40 years ago purchasing departments both in the public and private sectors viewed themselves as essentially the purchasing police. Despite a general change in attitude at most governmental contracting authorities, there are unquestionably many who continue to cling to this view. Consistent with the belief that "the only product of government is process", those of the purchasing police mentality are completely preoccupied with such weighty matters as whether the correct form was filled out and filed within the time allowed, whether it had the requisite signatures in the right places, all of which were affixed with an appropriate authority, and whether the correct reports were filed on time and with the right people. To the individuals still of this mindset, whether or not the municipal procurement function furthers or undermines overall municipal operations is completely beside the point.
While all of us recognize the importance of following the rules, I think it is safe to say that the purchasing function does not end with the rules. Far more important considerations are at stake. It is, in my opinion, the critical goal of public procurement at all levels of government is to get the taxpayer a good deal — or, at the very least, to exercise every precaution to avoid having the taxpayer saddled with a bad deal. In advancing the idea that public procurement should be more result-oriented, I am not alone.
Strategic planning within a municipality is a joint responsibility of the municipal council and its senior management. Responsibility for strategic planning is ongoing in nature, rather than a once and for all thing. A suitable strategy must be pursued on a continuous basis and matched to the changing circumstances of the municipality and the market in which it competes.
Ongoing strategic planning has become more critical as the pace of change accelerates. At times, if requires not simply adjustment by individual municipalities, but changes across the entire municipal sector — as, for instance, due to the practice of downloading responsibilities to municipalities from senior levels of government.
Strategic purchasing is a systematic approach towards reducing procurement cost while improving the quality of supply, and enhancing the internal process of control. Although my focus has always been on procurement, it is worth observing that the business planning process integration and coordination among the various decision making and operating levels of the municipality is critical.
If a plan is to be carried into effect, it is essential that all operational levels understand the long-term direction of the municipality. The practical implications of a proposal must be taken into account. One of the main goals of critical review is to ensure that these requirements are satisfied.
Stephen Bauld is a government procurement expert and can be reached at email@example.com.
Some of his columns may contain excerpts from The Municipal Procurement Handbook published by Butterworths.

subset: commoncrawl


text: PICTURS: ACTRESS,ADAORA UKOH SHAVES HER HAIR FOR N2 MILLION IN NEW MOVIE ADAORA UKOH starrs in a transitional movie role with a working title THY KINGDOME COME. alongside SAM DEDE , KENNETH OKONKWO, MAUREEN SOLOMON, MIKE EZURONYE, etc. She played a multiple character from young to old and even went as far as shaving off her hair in same movie. The movie celebrates the existing tradition of an igbo royal household. and also reveals the challenges a king could go through just to keep his throne and blood lineage on if he cant have children..... 'this movie is a wonderful story and dear to my heart so i was willing to go the extra mile for intepretation. in the course of making this movie i learnt tradition that i never knew' says Adaora Ukoh............ its a must watch." MOVIE STORY AND DIRECTED BY IYKE ODIFE SCREENPLAY BY EMEKA AMAKEZE STORY BY............. POTECH NIG. Previous Article CONTROVERSIAL RAPPER,RUGGEDMAN IN THEFT SCANDAL Next Article MOHITS STAR,D'BANJ ALLEGED ARREST FOR DRUG TRAFFICKING Previous Article CONTROVERSIAL RAPPER,RUGGEDMAN IN THEFT SCANDAL Next Article MOHITS STAR,D'BANJ ALLEGED ARREST FOR DRUG TRAFFICKING Share This Story facebook twitter google+ linkedin Whatsapp email Unveiled Beautiful Women Ready To Battle For Miss Earth Nigeria Crown Get Well Soon: Actress, Kemi Afolabi Hospitalized For Serious Health Issues In Saudi Arabia (PHOTOS) Why Actress Ruth Eze Spills On Tasha Big Brother Naija Strong Warning To Tope Alabi On How To Make Heaven From Evangelist Victor Edet COZA Scandal: Police Storm Busola And Timi Dakolo Residence Rape Allegation: Timi Dakolo React To COZA's CAN Visit Revealed! Actress, Dolly Nwaduba Who Plot Of kidnapping Her Ex On His Wedding Day Funke Akindele Warn Her Friends Against Calling Or Visiting Husband! Trending Stories SCANDAL: My Affair With Pastor Biodun Fatoyinbo Of COZA – Ese Walter See Stunning Pre-wedding Picture Of Former Militant Leader, Ateke Tom's Daughter Women Acting is Abnormal where I come from-Rahama Sadau Actress, Mercy Macjoe Undresses for the Camera (photos) See this Unbelievable Throwback Picture of Bobrisky My Embarrassment On Live TV Over Sex Was Taken Too Far - Reakado Banks Actor, Sam Sunny Mcdon in Secret Romance with Amanda Ebeye Latest News Naomi Campbell: Blocked From Entering French Hotel Because She's Black Trouble Man: Regina Daniel's Brother Arrested Again Nigerian Actress Confess Her Darkest Secrets Along Admiralty Way, Lekki Why Girls Follow Me – Pretty Mike View More Latest News Nigeriafilms Nollywood


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A well-designed yolk-shell Fe3O4@graphitic carbon (YS-Fe3O4@GC) submicroboxes with a tunable internal cavity were constructed by one-step pyrolysis strategy followed by partially etching, in which the Fe3O4 magnetic core was well confined in compartment of GC submicroboxes. The suitable internal cavity, graphitic carbon shell and large specific surface area, play great roles in improving mass transfer of analytes. Compared to its core-shell structure, the YS-Fe3O4@GC submicroboxes as dispersive magnetic solid-phase extraction (d-MSPE) materials exhibited superior enrichment performance for sulfonamides (SAs). Thus, it was applied to sensitive/simultaneous detection of trace SAs in milk and meat samples, combing with high performance liquid chromatography (HPLC). Under optimized conditions, limits of detection (LODs, 0.11-0.25⯵gâ¯L-1 for milk and 0.46-2.24⯵gâ¯kg-1 for meat) and recoveries (77.2-118.0%) were obtained. This work not only offers a facile strategy for the tunable fabrication of yolk-shell architecture, but also successfully affords its exploration as d-MSPE materials.
AssuntosAnálise de Alimentos , Grafite/química , Extração em Fase Sólida/métodos , Sulfonamidas/isolamento & purificação , Animais , Cromatografia Líquida de Alta Pressão , Compostos de Ferro/química , Limite de Detecção , Magnetismo , Carne/análise , Leite/química , Sulfonamidas/análise
Brain glioma is the most common malignant tumor of the central nervous system, and one of the leading causes of death in patients with intracranial tumors. The clinical outcome of glioma is usually poor due to abundant vascularity, fast growth and susceptibility of invasion to normal brain tissues. Our microarray study showed that lncRNA-LINC01116 was significantly upregulated in glioma tissues and played an important role in cell proliferation, cycle, migration, invasion and angiogenesis. In addition, vascular endothelial growth factor (VEGFA) may be the major target genes in the downstream of lncRNA-LINC01116. Dual luciferase assay showed that LINC01116 and VEGFA both contained a miR-31-5p binding site, and LINC01116 could regulate the expression of VEGFA through competitive absorption of miR-31-5p. RNA immunoprecipitation indicated that LINC01116 and VEGFA were present in the miR-31-5p-RISC complex, and biotinylated miR-31-5p pull-down assay suggested that there was a competitive relationship between LINC01116 and VEGFA to bind with miR-31-5p. Collectively, our study has identified a novel lncRNA-LINC01116 and clarified the role and mechanism of LINC01116 in the tumorigenesis of glioma. LINC01116 may prove to be a potential target for the clinical diagnosis and treatment of glioma.
BACKGROUND: Gastric cancer (GC) incidence and mortality in China remained high due to delayed diagnosis and accounted for about half of the world's GC cases and deaths. Early detection with endoscopic screening and consequent timely treatment can significantly improve survival. This study aimed to explore the long-term population impact of endoscopic screening on national GC disease burdens in China. METHODS: Most of previous studies investigated the disease burdens of cancer using Markov model or age-period-cohort (APC) model, which are difficult to estimate the population size of undiagnosed cases. In this paper, we proposed a new dynamic compartmental model based on GC natural history and calibrated model outputs to diagnosed GC cases and GC-related death counts using Markov Chain Monte Carlo methods. We investigated the impact of screening strategies with various coverage (10%, 40%, 70%) and frequency (every 1, 3, 5 years) on disease burdens. RESULTS: We estimated that 2.22 (95%CI: 1.97-2.47) million Chinese are living with GC in 2019, among which, 42.7% (40.3-45.0%) remained undiagnosed. Without systematic screening, we projected 10.46 (9.07-11.86) million incident cases and 7.35 (6.59-8.11) million GC-related deaths over the next 30 years (2019-2049). Screening with coverage rate at 10%, 40%, 70% every 3 years could prevent 0.85 (0.63-1.06), 2.32 (1.79-2.86), and 3.04 (2.38-3.70) million incident cases, and prevent 1.17 (1.01-1.32), 3.08 (2.70-3.46), and 3.93 (3.46-4.40) million deaths respectively, compared with 'no screening' scenario. Screening would substantially increase the number of diagnosed GC cases within the first three years of program initiation, but this number would quickly reduce below 'no screening' scenario. Three-yearly screening at the above coverage rates would reduce the proportion of undiagnosed GC cases to 38.8% (36.9-40.7%), 25.5% (23.4-27.6%), and 17.8% (16.0-19.6%) by 2049, respectively. Delaying implementation of the screening program would substantially reduce its effectiveness. CONCLUSIONS: Initiating national endoscopic screening programmes would likely have a major effect on reducing GC incidence and mortality in China. Health resources should be substantially increased and directed to treatment of GC to cope with the initial rise in diagnosed GC cases.
Atherosclerosis is an inflammatory disease of the arterial wall, which involves endothelial cells and immune cells. Endothelial dysfunction has been considered an important step in the initiation of the disease. TIPE1 is a newly identified protein of the TIPE family, and plays a vital role in inflammation and tumorigenesis. However, its role in atherogenesis remains unclear. In this study, we demonstrated that TIPE1 promoted atherogenesis by inducing endothelial dysfunction. When human umbilical vein endothelial cells (HUVECs) were exposed to oxidative stress, the level of TIPE1 was significantly up-regulated, and the ROS generation markedly increased in TIPE1 over-expressing HUVECs. As a result, the growth of HUVECs was inhibited, and the apoptosis was enhanced. However, the cell contact ability between HUVECs and THP-1 cells were augmented due to the up-regulation of adhesion molecules such as E-selectin and ICAM-1 induced by TIPE1 overexpression. Importantly, ApoE-/- mice injected with TIPE1 recombinant lentivirus developed significantly severe atherosclerosis accompanied by hyperglycemia, hypercholesterolemia and increased white blood count. These findings indicated that excessive ROS induced by the overexpression of TIPE1 in endothelial cells accelerated the process of atherogenesis.
Renal interstitial fibrosis is a key factor in the development of chronic renal diseases, possibly leading to uremia. The present study conducted aimed to assess the hypothesis whether keratin 1 (KRT1) silencing could suppress kidney interstitial fibrosis and glomerular sclerosis via the Notch pathway to alleviate uremic symptoms. Differentially expressed genes associated with uremia were identified using the gene expression omnibus (GEO) database. Uremic rat models were established, in which short hairpin-RNA against KRT1, activators, and inhibitors of the Notch pathway were transfected. To further validate the mechanism of KRT1 in uremia, KRT1 expression, cell apoptosis, glomerular area (GA), and glomerular capillary volume (GV), the score of glomerular sclerosis, and tubulointerstitial injury were assayed and investigated. GEO database revealed that KRT1 was upregulated in uremia and regulated the Notch pathway. GA, GV, cell apoptosis, glomerular sclerosis, and tubulointerstitial injury were typically located in more elevated levels of uremia in rats. KRT1 silencing and Notch pathway inhibition decreased the expression of Jagged1, Notch1, NICD1, Hey1, Hes1, α-SMA, and FN, which further resulted in decreased cell apoptosis, GA, GV, the score of glomerular sclerosis, and tubulointerstitial injury. Subsequently, the effect of KRT1 silencing on uremia was no longer evident once the Notch pathway was activated. The co-localization of high expression KRT1 and Notch1 was found in uremia. In summary, the results identified KRT1 as a key regulator in uremia progression, and KRT1 silencing can suppress glomerular sclerosis and tubulointerstitial injury via inactivation of the Notch pathway in uremic rats.
In this work, 3D hierarchical Cu2SnS3@SnS2 flower assembled from nanopetals with sandwich-like Cu2SnS3-SnS2-Cu2SnS3 double interfacial heterojunction was successfully designed and synthesized on fluoride doped tin oxide (FTO) for photoelectrochemical (PEC) sensor by in situ electrodeposition p-type Cu2SnS3 nanoparticles on both inner and outer surfaces of n-type SnS2 nanopetals. The unique double interfacial heterojunction simultaneously combines 3D flower-like architectures to drastically increase the light trapping and absorption in visible-near infrared range (Vis-NIR), and dramatically inhibites the charge carrier recombination, which is crucial for boosting the PEC activity. Benefitting from the shape and compositional merits, the Cu2SnS3@SnS2 heterojunction possess dual-mode signal by controlling the electrodeposition time to manipulate the composition ratio of Cu2SnS3 and SnS2. The Cu2SnS3@SnS2/FTO electrode not only exhibits excellent photoeletro-reduction capacity for ultra-sensitive sensing trace persistent organic pollutant (nitrobenzene, NB), but also presents photoeletro-oxidization activity for high selective detection of L-cysteine (L-Cys) without any auxiliary enzyme under the light illumination. Dual mode sensor displayed superb performance for the detection of NB/L-Cys, showing a wide linear range from 100 pM to 300 µM/10 nM to 100 µM and a low detection limit (3S/N) of 68 pM/8.5 nM, respectively. Such a tunable double interfacial heterojunction design opened up new avenue for constructing multifunction PEC sensing platform.
China has been suffering from endemic fluorosis for the past 30 years. This study investigated fluoride concentrations in 10 districts of Tianjin, China, to illustrate their spatial distribution characteristics and potential human health risks. The results showed fluoride concentration of 0.01-6.30â¯mgâ¯L-1 with a mean value of 0.99â¯mgâ¯L-1, and 78.82% of water fluoride reaches the standard for drinking water (1.5â¯mgâ¯L-1). Higher fluoride levels were recorded in deep well pumps supply zones, and more potential changes in fluoride occurred was positively correlated with pH in groundwater. Mean value of fluoride in drinking water in 10 districts followed the order of WQâ¯>â¯BCâ¯>â¯JZâ¯>â¯NHâ¯>â¯BDâ¯>â¯BHâ¯>â¯JNâ¯>â¯JHâ¯>â¯DLâ¯>â¯XQ. Estimations of non-carcinogenic risk for drinking water indicated that mean hazard quotient values of fluoride for combined pathways (i.e., oral ingestion and dermal absorption) were >1.0 for all age groups of WQ and BC. The results also showed that the estimated risk primarily came from the ingestion pathway. Risk levels for children varied obviously, generally in the order of 1-4yâ¯>â¯4-7yâ¯>â¯7-9y (years old). In the central tendency center and reasonable maximum exposure conditions, estimated risks were 1.25, 1.12, 0.771 and 3.66, 3.29, 2.27, respectively. The results supply material information for health authorities in fluorosis areas to put forward more efficient policies to control the endemic diseases. Attention should be paid to the formulation of health promotion strategies and measures to reduce fluoride intake in order to protect the health of residents.
BACKGROUND: Although gankyrin has been identified as a vital regulator of tumorigenesis, its role and regulatory mechanism in osteosarcoma (OS) remain unclear. METHODS: QRT-PCR, western blot and IHC staining were conducted to detect the expression of gankyrin in OS. Pearson's χ² test was adopted to examine the associations between gankyrin expression and clinicopathologic characteristics. Kaplan-Meier method was used to investigate the relationship between gankyrin expression and overall survival of patients with OS. Next, a series of in vitro and in vivo assays were performed to determine the positive feedback loop between gankyrin and YAP in OS. RESULTS: We first reported that gankyrin is upregulated in human OS specimens and cell lines and predicts OS progression and poor prognosis. Furthermore, we demonstrated that gankyrin protects miR-200a-mediated yes-associated protein (YAP) downregulation through p53 and establishes a positive feedback loop to regulate YAP signaling in U2OS and MG63 cells. Intriguingly, gankyrin interacts with YAP to promote OS cell growth in vitro. In addition, our results showed that gankyrin promotes OS tumor growth and regulates YAP levels in vivo. Notably, we also observed a positive correlation between gankyrin and YAP expression in human OS tissues, and co-upregulation of gankyrin and YAP indicated a poor prognosis. CONCLUSIONS: Our results identify that gankyrin acts as an oncogene in OS by forming a positive feedback loop with YAP, and disrupting the gankyrin-YAP regulation may be beneficial for controlling OS tumorigenesis.
Quantification of plasma membrane proteins (PMPs) is crucial for understanding the fundamentals of cellular signaling systems and their related diseases. In this work, a super-quadruplex scaffold was designed to regulate assembly of oligonucleotide-grafted AIEgens for detection of PMPs. The nonfluorescence oligonucleotide-grafted AIEgen (Oligo-AIEgen) was firstly synthesized by attaching the AIEgen to 3'-terminus of the oligonucleotide through click chemistry. Meanwhile, the tetramolecular hairpin-conjugated super-quadruplex (THP-G4) as cleavage element and signal enhancement scaffold composited of three elements: a substrate sequence of DNAzyme in the loop region, partial hybridization region in the stem, and six guanine nucleotides to form G-quadruplex. Once the DNAzyme was anchored on the specific PMPs through aptamer-protein recognition, the substrate sequence on the loop of THP-G4 was cleaved by DNAzyme with the aid of cofactor MnII, resulting in the conformation switch of THP-G4 to the activated G-quadruplex scaffold. The latter could assemble Oligo-AIEgens to generate aggregation-induced emission (AIE) enhancement, resulting in a simple and sensitive strategy for detection of membrane proteins. Moreover, the DNAzyme continuously cut the next THP-G4 to achieve recycling amplification. Under the optimized conditions, this AIE-based strategy exhibited good linear relationship with the logarithm of MUC1 concentration from 0.01 to 10⯵gâ¯mL-1 with the limit of detection down to 4.3â¯ngâ¯mL-1. The G4-assembled AIEgens provides a universal platform for detecting various biomolecules and a proof-of concept for AIE biosensing.
Source diverted blackwater collected from toilets can be anaerobically digested to recover energy. The anaerobically digested blackwater (ADB) contains high levels of ammonium and low carbon to nitrogen (C/N) ratio. In the present study, ADB was treated by a two-stage nitritation-denitrification/anammox process in an integrated fixed film activated sludge-continuous flow reactor (IFAS-CFR). NH4+-N, NO2--N, total nitrogen (TN), and chemical oxygen demand (COD) removal efficiencies were 80%, 82%, 76%, and 78%, respectively. Anaerobic ammonium oxidation (anammox) and denitrification contributed to 44-48%, and 52-56% of total nitrogen removal, respectively. Both of the protein- and humic acid-like matters were removed during the process. An increase in feed load promoted the sustained growth of anammox bacteria-Candidatus Brocadia in the biofilm, as well as an increase of denitrifiers (Pseudomonas, Thermotonus, Phodanobacter, Caulobacter) in both biofilm and suspended biomass, which remained higher in the suspended biomass than in biofilm. Overall, biofilm had higher nitrogen removal efficiency than suspended biomass, while suspended biomass had a higher COD removal efficiency than biofilm.
A dual-optimized adaptive Kalman filtering (DO-AKF) algorithm based on back propagation (BP) neural network and variance compensation was developed for high-sensitivity trace gas detection in laser spectroscopy. The BP neural network was used to optimize the Kalman filter (KF) parameters. Variance compensation was introduced to track the state of the system and to eliminate the variations in the parameters of dynamic systems. The proposed DO-AKF algorithm showed the best performance compared with the traditional multi-signal average, extended KF, unscented KF, KF optimized by BP neural network (BP-KF) and KF optimized by variance compensation (VC-KF). The optimized DO-AKF algorithm was applied to a QCL-based gas sensor system for an exhaled CO analysis. The experimental results revealed a sensitivity enhancement factor of 23. The proposed algorithm can be widely used in the fields of environmental pollutant monitoring, industrial process control, and breath gas diagnosis.
Colorimetric sensor array is a sensitive, rapid, and inexpensive detection technology which simulates human olfaction system based on various organic dyes. In this work, a sensor array based on acid-sensitive CdTe QDs coupled with chemometrics method was developed and proved to be a rapid, accurate and sensitive method for identification of 32 kinds of Chinese traditional cereal vinegars (CTCV). The specificity of identification of this method was mainly depends on the organic acids and melanoidins of CTCV. Among them, organic acids can quench the fluorescence of QDs through enhancing their electron transfer (hydrogen bond) and resonance energy transfer, and the fluorescence intensity of melanoidin was closely related to the brewing technology and aging year of CTCV. The types and aging time of 32 CTCV can be 100% identified at a dilution of 1000 by partial least squares discriminant analysis, when the latent variables were 4. And only one kind of QDs is needed instead of various organic dyes to this kind of colorimetric sensor array. Except for vinegar, this method can also be used in the identification of other food which rich in organic acid.
Psoralen (P) and isopsoralen (IP) are the main active ingredients in the dried fruit of Psoralen corylifolia L. (PC), with a wide range of pharmacology activities. The intestinal bacteria biotransformation plays a central role in the metabolism of the complex ingredients in traditional Chinese medicine (TCM). Our study aimed to investigated the metabolic profile of P and IP in the intestinal condition, co-cultured with human fecal bacteria anaerobically. Four bio-transforming products were obtained, including 6,7-furano-hydrocoumaric acid (P-1) and 6,7-furano-hydro- coumaric acid methyl ester (P-2), which transformed from P, and 5,6-furano-hydrocoumaric acid (IP-1) and 5,6-furano-hydrocoumaric acid methyl ester (IP-2), which were transformed from IP. It is worth mentioning that IP-2 is a new compound that has not been published. Their structures were analyzed based on their spectroscopic data. Moreover, a highly sensitive ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was used to characterize the metabolic pathways of P, IP, and their bio-transforming products in the reaction samples. In addition, the dampening effects against the oxidative stress of P, IP, and their bio-transforming products by human intestinal flora were estimated in vitro via the human colorectal cells (HCT116) and heterogeneous human epithelial colorectal adenocarcinoma cells (Caco-2) cell lines. The results showed that the metabolites have stronger activity than P and IP, which possibly provides a basis for elucidating the treating mechanisms of PC extract against inflammatory bowel disease.
The first open hollow Sn13-oxo cluster family has been successfully prepared and characterized. These Sn13 clusters contain a {Sn7} moiety that is similar to the basic structure unit of rutile SnO2. Interestingly, the Sn13 clusters show labile coordination sites on the edge, which could be functionalized by different ligands. With the different decorated types of functionalized ligands, the open hollow Sn13 clusters present different structural details and framework diameters. The presented results provide a new open hollow structural motif of tin-oxo clusters and also a good platform for their ligand functionalization.
The study aimed to retrospectively investigate the clinical significance of anti-rods and rings (anti-RR) antibodies in antinuclear antibodies (ANAs) test samples of western China. Between January 2016 and November 2018, the laboratory data and clinical details of patients with positive anti-RR antibodies were collected and analyzed. The results showed that total of 197227 patients tested, 109453 patients presented with positive ANAs (55.50%), but only 107 patients with positive anti-RR antibodies (0.10%)ï¼including 51 females and 56 males. Diagnose were established in 51 of 107 patients: 25 were hepatopathy (HCV 8/25 and HBV 12/25); 13 were autoimmune diseases (AID); and 7 were renal insufficiency; 6 were chronic obstructive pulmonary disease (COPD). We make the conclusions that anti-RR antibodies have a low prevalence, and there is no gender difference. Anti-RR antibodies exist other diseases besides hepatitis C, such as HBV, some autoimmune diseasesï¼renal insufficiency and COPD, which we need further investigation.
Microneedles are primarily designed for enhancing transdermal drug delivery in a minimally invasive manner. In particular, coated microneedles have attracted increasing attention due to the resulting mode of rapid and highly efficient drug administration. In this study, we developed a novel gelatin/sucrose film-coated poly(ethylene glycol)diacrylate (PEGDA) microneedle patch, which can effectively improve the skin permeability of therapeutic drugs and realize convenient and efficient drug administration. A simple and reliable technique was proposed to produce uniform film coatings on microneedles at room temperature. After introducing a prepolymer solution into the mold cavity, a film-coated microneedle patch was fabricated via a photo-induced polymerization process. Four categories of molecular models, including rhodamine B (RhB), bovine serum albumin (BSA), doxorubicin (DOX) and indocyanine green (ICG), were encapsulated into the gelatin/sucrose film to evaluate their transdermal delivery and therapeutic effects both in vitro and in vivo. The presented methodology represents a facile technique for rapid formation of film-coated microneedles for efficient transdermal delivery of small molecular drugs and large proteins.
Colorectal cancer (CRC) is a major health problem and third most common deaths in western world. Dietary interventions together with modified dietary style can prevent the CRC in humans. Xanthohumol (XHA), a polyphenol isolated from Humulus lupulus L. contains many beneficial effects. The aim of the study is to analyze the effect of XHA on Azoxymethane (AOM)-induced experimental CRC in rats. Levels of MDA were increased and enzymic antioxidants levels were decreased in AOM-induced rats. However, these levels were reversed upon XHA treatment. Further, the mRNA expressions of iNOS and COX-2 were also downregulated in XHA treated rats compared to AOM-induced rats. Further, we found that administration of XHA suppressed the wnt/ß-catenin signaling together with modulation of apoptotic proteins Bax, Bcl-2, and caspase 3. We conclude that XHA can able to quench the free radicals, inhibits cell proliferation and induces apoptosis, thus it can be a chemopreventive/therapeutic agent against CRC.
The retrosplenial cortex (Rsp) is a transitional cortex located between the neocortex and archicortex, but the molecular mechanism specifying Rsp from the archicortex remains elusive. We here report that the transcription factor Satb2 is required for specifying Rsp identity during its morphogenesis. In Satb2 CKO mice, the boundary between the Rsp and archicortex [i.e., subiculum (SubC)] disappears as early as E17.5, and Rsp efferent projection is aberrant. Rsp-specific genes are lost, whereas SubC-specific genes are ectopically expressed in Rsp of Satb2 CKO mice. Furthermore, cell-autonomous role of Satb2 in maintaining Rsp neuron identity is revealed by inactivation of Satb2 in Rsp neurons. Finally, Satb2 represses the transcription of Nr4a2. The misexpression of Nr4a2 together with Ctip2 induces expression of SubC-specific genes in wild-type Rsp, and simultaneous knockdown of these two genes in Rsp Satb2-mutant cells prevents their fate transition to SubC identity. Thus, Satb2 serves as a determinant gene in the Rsp regionalization by repressing Nr4a2 and Ctip2 during cortical development.
Cancer cells reprogram their energy metabolic system from the mitochondrial oxidative phosphorylation (OXPHOS) pathway to a glucose-dependent aerobic glycolysis pathway. This metabolic reprogramming phenomenon is known as the Warburg effect, a significant hallmark of cancer. However, the detailed mechanisms underlying this event or triggering this reprogramming remain largely unclear. Here, we found that histone H2B monoubiquitination (H2Bub1) negatively regulates the Warburg effect and tumorigenesis in human lung cancer cells (H1299 and A549 cell lines) likely through controlling the expression of multiple mitochondrial respiratory genes, which are essential for OXPHOS. Moreover, our work also suggested that pyruvate kinase M2 (PKM2), the rate-limiting enzyme of glycolysis, can directly interact with H2B in vivo and in vitro and negatively regulate the level of H2Bub1. The inhibition of cell proliferation and nude mice xenograft of human lung cancer cells induced by PKM2 knockdown can be partially rescued through lowering H2Bub1 levels, which indicates that the oncogenic function of PKM2 is achieved, at least partially, through the control of H2Bub1. Furthermore, PKM2 and H2Bub1 levels are negatively correlated in cancer specimens. Therefore, these findings not only provide a novel mechanism triggering the Warburg effect that is mediated through an epigenetic pathway (H2Bub1) but also reveal a novel metabolic regulator (PKM2) for the epigenetic mark H2Bub1. Thus, the PKM2-H2Bub1 axis may become a promising cancer therapeutic target.
Eight-membered cyclic and [5,5]-bicyclic sulfides were synthesized via a domino reaction between thioaurone analogues and arynes. Density functional theory calculations were performed to elucidate the reaction mechanism, which involves the elementary steps of the [3 + 2] cycloaddition, 1,2-hydrogen shift, and C(sp2)-S bond cleavage as well as the substituent effect.


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Research Policies
- Funding Opportunities Announcement Guidance
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Project Research Online Database (PROD)
Searchable database of AHRQ Grants, Working Papers & HHS Recovery Act Projects
The Agency for Healthcare Research and Quality (AHRQ)'s programs offer practical information to help a variety of health care organizations, providers, and others make care safer in all health care settings.
1-10 of 42 Programs displayed
The National Quality Strategy is a national effort to align public- and private-sector stakeholders to achieve better health and health care for all Americans. It was first published in March 2011 as the National Strategy for Quality Improvement in Health Care, and is led by AHRQ on behalf of HHS.
AHRQ provides free continuing education events in the areas of comparative effectiveness, quality and patient safety, and prevention/care management.
The AHRQ Surveys on Patient Safety Culture (SOPS™) program enables health care organizations to assess how their staff members' perceive various aspects of patient safety culture in hospitals, medical offices, nursing homes, community pharmacies, and ambulatory surgery centers.
Evidence-based research provides the basis for sound clinical practice guidelines and recommendations. The recommendations of the U.S. Preventive Services Task Force are especially useful.
AHRQ's research-based resources for hospitals include toolkits, recommendations, and other resources to improve quality, reduce errors, and increase patient safety.
AHRQ offers toolkits, recommendations, and other resources for long-term care facilities to improve quality, reduce errors, and increase patient safety.
TalkingQuality is a comprehensive resource and guide for organizations that produce and disseminate reports to consumers on the quality of care provided by health care organizations (e.g., hospitals, health plans, medical groups, nursing homes) and individual physicians.
The Patient Safety and Quality Improvement Act of 2005 authorizes AHRQ to list or designate entities as PSOs that attest to having expertise in identifying the causes of, and interventions to reduce the risk of, threats to the quality and safety of patient care. The primary activity of an entity or component organization seeking to be listed as a PSO must be to conduct activities to improve patient safety and health care quality.
AHRQ's health information technology (IT) initiative is part of the Nation's strategy to put information technology to work in health care. By developing secure and private electronic health records for most Americans and making health information available electronically when and where it is needed, health IT can improve the quality of care, even as it makes health care more cost-effective.
AHRQ offers free resources that care providers can use with their teams and share with their patients.


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Yoga Classes
Each audio yoga class is recorded with love and shared in gratitude. Please accept any extra sounds just as you would in your favorite yoga studio.
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General Physics
1-D Particle Kinematics
1) An 18-year-old runner can complete a 10.0-km course with an average speed of 4.87 m/s. A 50-year-old runner can cover the same distance with an average speed of 3.46 m/s. How much later (in seconds) should the younger runner start in order to finish the course at the same time as the older runner?
2) A bicyclist makes a trip that consists of three parts, each in the same direction along a straight road. During the first part, she rides for 23.0 minutes at an average speed of 32.0 ft/s. During the second part, she rides for 36.0 minutes at an average speed of 17.0 ft/s. Finally, during the third part, she rides for 9.10 minutes at an average speed of 48.0 ft/s. (a) How far has the bicyclist traveled during the entire trip? (b) What is the average speed of the bicyclist for the trip?
3) A high-performance car accelerates from zero to 26.8 m/s (60 mi/h) in 3.21 s. What is the car's acceleration, in m/s2?
4) In getting ready to slam-dunk the ball, a basketball player starts from rest and sprints to a speed of 29 ft/s in 1.4 s. Assuming that the player accelerates uniformly, what is the distance he runs?
5) The left ventricle of the heart accelerates blood from rest to a velocity of +28 cm/s. (a) If the displacement of the blood during the acceleration is +1.4 cm, what is its acceleration (in cm/s2 )? (b) How much time does blood take to reach its final velocity?
6) From her bedroom window a girl drops a water-filled balloon to the ground, 16.1 ft below. If the balloon is released from rest, how long is it in the air?
7) A wrecking ball is hanging at rest from a crane when suddenly the cable breaks. The time it takes for the ball to fall halfway to the ground is 3.9 s. What is the time it takes for the ball to fall from rest all the way to the ground?
8) A bus makes a trip according to the position-time graph shown in the drawing. What is the average velocity (with appropriate sign) of the bus during (a) segment A, (b) segment B, (c) segment C, and (d) the entire trip? Express your answers in km/h.


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I am involved in a pre-seed project with another person. When I started this project I was looking for a person who I thought would take care of the administrative and executive tasks of the company while I handled the technology and finances. I found my cofounder, Adam, because I thought he was this kind of person.
I didn't really know Adam when I agreed to start this project with him. As I've worked with him for 3 months I've realized that for the project to succeed, it will be without him as cofounder. When we started to build the product, it went how I thought it would. However, as time went on Adam started wanting to be a more of a developer, even though he had no developer experience. We built a product together that was horrible and hacked together because half of my time was spent mentoring him and fixing his code.
It's obvious to me now that what he wants to do is different than what I wanted him for. I've built a new product from scratch, completely myself, and I've stopped pushing code because I'm frankly afraid of his drag on it and I work much more quickly without him. I know that he doesn't think long-term enough to take the company where I want to take it. Essentially, I was looking for a CEO and I see now that he is not fit to be CEO of this company. I own everything and I have to do everything myself. I own the domain, the email inboxes, the code for the landing page, the product, and all the labor that has gone into this new version. I do not know why I'm continuing to allow him to be take credit. However, I know that he feels ownership of the idea since we formed the idea together and this is the only leverage he has.
Basically the way I see it I have 3 paths: 1) Act like everything is cheery and let him take 50% of a company that I built and own. I allow him to take CEO role and I am unhappy. 2) Reduce him to a minority position, around 20%. This is basically just a consolation prize, because he was around and provided "moral support" through the first iteration cycle of a failed product. I don't even know what his role will become, maybe "community manager." 3) Separate from him. Basically tell him that he is no longer involved in the project. The project is mine, I own the assets and built the product. We don't sign a non-compete and he can take my code once I publish it and fork the project if he wants. I don't care.
Overall my largest dilemma is that I know he's bad at organizing work priorities, has personal weaknesses that makes him a bad leader, doesn't engage in the same form of long-term thinking that I do, lacks overall project vision that is ambitious enough, and requires a lot of nurturing from my end. I've changed my mind about wanting him involved.
What can I do?
Am I being sociopathic / anti-social by thinking all this?
EDIT: No legal contracts, verbal commitments and emails up to this point has made clear we plan to split equity 50 - 50 in the case that an entity was formed. Locale is the EU.
EDIT2: I added the "unlucky" descriptor because he went broke 1 month into the project because he had mismanaged his personal finances. I did not know this at the time. It was overall detrimental to the project since it put an unnecessary burden on us to raise funds before we had reached the right maturity to do so. Because of this, I've also been working full-time on this while he's taken a 30/hr week job at another startup. He was supposed to continue working but all he's done for the last week has been send some emails.


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On the strength of first place finishes by freshman Gabriel Ballesteros (Mesa, AZ HS) and sophomore Tyree Cox (Lancaster HS), the Cerritos College wrestling team placed second at the West Hills Tournament on Saturday. Ballesteros won the 125-pound weight division, while Cox swept through at 184 pounds for the Falcons, who also had four third place finishers and six who came in fourth place. On the day, Cerritos compiled 126 team points and trailed only Sierra College, who had 140.5 points. The team will now compete in the Santa Ana Tournament on Saturday.
For Ballesteros, he entered as the #1-seed and opened with a pin over Kyle Doughty of Santa Rosa College in 6:08, followed by a thrilling 7-6 victory against Brian Santana of Chabot College. A pin in 3:22 against Yubini Barerra of Chabot in the semi-finals sent him into the championships, where a reversal in overtime secured an 8-6 decision against Silverio Esparza of West Hills College Lemoor in the finals.
As for Cox, another top seed, he received a bye in the first round and then posted a 10-3 decision over Tyler Wood of Sierra College. In the semi-finals, Cox earned a technical fall 16-0 win against Justice Cortez of West Hills College Lemoor before recording a 5-2 decision against Quentin Becker of Sierra College for the championship.
At 141 pounds, a pair of Falcons faced each other in the third place match, with Joshua Ewing (Mesa, AZ HS) defeating freshman Michael Behnke (Arlington HS), 8-6 in overtime. Ewing worked his way into the third place match through the consolation round, while Behnke was defeated in the semi-finals by eventual champion Michael Ruiz of West Hills Lemoor. The same scenario played out at 157 pounds, with freshman Yuuki Murai (West Torrance HS) defeating sophomore Dylan Garriott (North Torrance HS), 7-4 for third place. Both won their first match, but were defeated in the quarter-finals before winning three straight matches to meet up in the third place match.
The third pair of Cerritos wrestlers to square off for third place came at 197 pounds, where freshman Tyler Smith (Marina HS) was credited with a win over sophomore George Knight (Corona HS). Smith was in the semi-finals before losing, while Knight lost his first match and then won four straight to meet up with SMith.
Also placing third in the tournament was freshman Dylan Clarke (Burnt Hills, NY HS), who was pinned in the semi-finals by eventual champion Robin Callas of Sierra. But Clarke came back and won two straight matches, including an 11-7 decision against Romen Ornea of Victor Valley College for third place.


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- light89stitch
- 9 years ago
Ok, so I was reading the boards obsessively (as you do) this morning and saw a post by @kmurley that made me go 'AHA!'
I have been so hung up about how to dye my hair for the wedding so am coming to the bee for help!
Please be brutally honest (I promise I won't take it to heart or start hating on you!) – I am relying on the awesomeness of the bees here! (I love my hair any colour but just want to have what looks BEST on the wedding… you know how I feel I am sure!)
[attachment=1371727,174086] With a great g/f
[attachment=1371727,174087] With a LOVELY ex
[attachment=1371727,174088]With a great friend
[attachment=1371727,174089] Me looking drunk and silly


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Nick & Norah's Infinite Playlist opens up on what appears to be the same street where Juno was filmed. This is no accident. Like Juno, it also stars Michael Cera as a sensitive young man somewhat befuddled by women who throws himself into his hobby as a way to deal with the outside world. Here, that hobby is playing and listening to music. And like Juno, the leading lady is a sharp-talking brunette who might be a little too aggressive for him but still has a heart of gold.
The comparisons aren't terribly flattering for Nick & Norah, which doesn't have the thematic depth or scintillating dialogue of its predecessor. But it does have Cera, who continues to play a variation of his wonderful Arrested Development character (no complaints from me), and Kat Dennings as Nora, who's endearing and compelling. In fact, the scenes with just the title characters are pretty wonderful, as they slowly come to realize they like each other, despite some holdover feelings for old exes.
The problem is the movie keeps tearing us away from our protagonists and focusing on those exes or other friends, who can't match Nick and Norah in the personality department. This is a bit unusual, as most romantic comedies feature sidekicks that are at least as interesting and quirky as the leads. Not so here, and so the inevitable scenes designed to keep our lovers apart quickly grow irritating.
I was also a bit surprised that director Peter Sollett, who made the wonderful Raising Victor Vargas, doesn't capture the vibrancy and specificity of Manhattan nightlife. This feels like it could've been made in any city. And am I the only one who was consistently surprised at how the characters kept driving around New York and, even more amazingly, kept finding parking spaces? At least the wall-to-wall music is good, befitting a movie that's about how people find each other in a song. If it had focused just on that, we might have been talking about moving beyond Juno, instead of falling short.
5 Responses to "Nick & Norah's Infinite Playlist"
there were some awkward moments in this movie that were hard to get past... such as every time that gum was passed around (yuck!)
Wow ... I don't like this film more than you do (I like it less, probably), but I had almost the opposite reaction. I don't think Cera works at all as a lead actor -- he's about as acharismatic as you can get. And Dennings is only good by comparison.
As for New York, it dawned on me while I was watching FIREPROOF right after that part of the reason I did not connect with NICK AND NORAH is that it was so specifically set in a world with which I simply could not connect -- gallivanting around New York club-hopping until dawn, leaving cars and drunk friends around, sex the first day you meet. Whatever my uneasy relationship to small-town Southern Protestant culture, it's at least a world I can mentally and emotionally navigate my way around. (And the reverse for most blue-state secular film critics.)
I have never seen Arrested Development.


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After you have a baby you will hear loads about your pelvic floor muscles and how you should be exercising them.
But what are they? And should you really wait until your baby is born to strengthen them?
Here is all you need to know.
What are pelvic floor muscles?
The pelvic floor muscles are the layer of muscles that support the pelvic organs and span the bottom of the pelvis.
The pelvic organs are the bladder and bowel in men, and bladder, bowel and womb in women.
Why you should strengthen them
These muscles basically stop you from peeing yourself, as well as giving you better sensations during sex. While you will be advised to do pelvic floor exercises post baby, it is actually beneficial to incorporating them into your routine before you even become pregnant.
Studies have shown that healthy, fit muscles before the baby is born will mend more easily after the birth and helps to reduce or avoid stress incontinence after pregnancy.
Also, incontinence is common during pregnancy so fit pelvic floor muscles will help with that too.
How to do it
Strengthening your pelvic floors is so easy and you can do it anywhere. All you have to do is sit comfortably and squeeze the muscles (as if you are stopping yourself from peeing) 10-15 times in a row.
Make sure not to clench or tighten the rest of your body or you could strain something. Just breath and relax and do it as often as you like.
Here is some info from the HSE on the exercises.
Chat about this, or anything else, over on our discussion boards.


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text: Ronnie \r(on)-nie\ as a girl's name (also used as boy's name Ronnie), is a variant of Roanna, Ronni (Old English) and Veronica (Latin), and the meaning of Ronnie is "strong counsel, true image". The baby name Ronnie sounds like Rennie and Ronnee. Other similar baby names are Bonnie, Connie, Donnie, Nonnie, Jonnie, Lonnie, Sonnie and Vonnie. View a list of the 3 names that reference Ronnie.


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It's the last day to participate: Christie's auction house have unveiled a handful of rare bags dreamed up by some of the biggest fashion houses, and the bidding isn't open for much longer.
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Calfbox, Hermès, 1960s
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Chanel clutch, 2014
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Translated by Ashe de Sousa


text: I may just be completely miss understanding the system but their appears to be something wrong with the resource system As you can see i should be getting 375 per day from this territory which i have farms on. How ever it also says that my next harvest is due in 247 hours 50 minutes. Is emptying the harvester a separate action from the amount of resources per day? If so i cant say I'm noticing 374 resources landing in my pocket every 24hr.


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(Deprecated) Insight Reporting API
The Insight reporting tool is designed to provide fast, reliable access to standard, every day reporting needs. To do this, Pulse pre-aggregates typical combinations of filters, dimensions, and metrics and makes them available to report against directly within the Insight UI or through the Insight API. Insight also allows some additional combinations of filters, dimensions, and metrics to be configured by the publisher as custom templates in the Insight UI.
Getting Started
- Base URL:
- Insight Report Requests: https://api.videoplaza.com/api/2.0/report
- Insight Report Definition Requests: https://api.videoplaza.com/api/2.0/report-definition
- Requests: GET and POST requests are used. You pass parameters by using common REST parameters like PATH and QUERY, as well as HTTP HEADERS. The body of the requests should be provided in JSON format and encoded using UTF-8.
- Responses: All responses contain an HTTP status code in the header and the body is in JSON format.
- Swagger documentation: https://api.videoplaza.com/docs
- Related user documentation:
The Insight Reporting API allows you to manage your reports and report definitions:
The following limitations apply to the Insight Reporting API:
- You can only create Insight reports based on existing Insight report definitions. You cannot create new Insight report definitions.
- Retrieving an Insight report returns report data without subtotals.
- You cannot pull an Insight report as Excel or view a report in browser.
- You cannot share an Insight report.
- You cannot add an Insight report to a relevant menu, for example the standard "Campaign performance by creative" report cannot be added to the campaign menu.


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Poison Ivy is a former botanist turned eco-terrorist and an enemy of Batman. She is voiced by Natasha Leggero.
History Edit
Biography Edit
Background Edit
Relationships Edit
Harley Quinn- Best Friend
Swamp thing-love interest
Powers, Skills, and AbilitiesEdit
- Enhanced Intelligence
- Plant Manipulation
- Chlorokinetic Combat
- Mind Control
- Pheromone Manipulation
- Scientific Prowess
- Chemistry Intuition
- Chlorokinesis
- Pheromone Control
- Toxikinesis
- Toxic Immunity
- Botany
- Toxicology
- Seduction
Weapons Edit
- Green Bamboo Staff
- Vine Whip
- Plant Seed Bombs
Weaknesses Edit
- Mental Instability
Appearance Edit
Ivy has white skin, green eyes, black lipstick, and red hair that reaches down on her left shoulder, consisting a leaf as well. Her out fit consists of a dark green leaf chest plate as well as grass-like skirt, a green neck collar, dark green gloves, dark green high heeled boots, and the right side of a pair of dark green leggings down her right leg. Unlike other carnations of her, she wears a leaf on her head like a french beret.
Appearances Edit
- Garden of Evil (First Appearance)
- System Error (robot)
Community content is available under CC-BY-SA unless otherwise noted.


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Two Point Hospital – Announcement Trailer | PS4
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SK gets Award at 2017 Annual TODAY's Awards Dinner Event
Todays have awarded SK the RISING STAR award at it's 30th Anniversary Awards Dinner in March 2017. This award was given on the basis t
We have been approved for AWRS
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Natco Almonds 100g
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© SK food & Drinks LTD. ALL rights reserved. Designed & Developed by www.multichannelcreative.co.uk


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New Finding Aids | Children's Literature
New finding aids are now available on Archives West for the following children's literature collections:
Bettina Ehrlich papers, circa 1959 (A 230)
Bettina Ehrlich (1903-1985) was an Austrian artist and author of children's books. The collection includes Ehrlich's manuscripts, sketches, and illustrated dummy for For the Leg of a Chicken.
Joseph Edward Van Wormer papers, 1961-1974 (Ax 770)
Joseph Edward Van Wormer (1913-1998) was an Oregonian wildlife photographer and author. The collection includes Van Wormer's literary manuscripts for eight books about animals of the Northwest, mostly for children, and related correspondence.


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Ross Family Pulling's "Triple Bypass" Earns Third SSD Championship in Four Seasons
Jody, Colin, and Lily Ross (Waynesburg, Pennsylvania)
"Triple Bypass"
2019 NTPA Grand National Super Stock Diesel Champions
Flash a "three" for RFP. That's "three" as in chargers for the "Triple Bypass" McCormick. "Three" as in a third Grand National championship for the team from Waynesburg, Pennsylvania. And "three" as in drivers over the course of the 2019 season, which welcomed Lily into the fraternity of Super Stock Diesel competition in Fort Recovery and for two late-season events in Napoleon and Sandwich. We might note that Jody's daughter/Colin's sister put up a 3-0 record in those Ohio and Illinois outings. But that performance was par for "Bypass," which posted 10 wins in 16 outings---including seven straight to open the campaign--- and finished out of the top three precisely twice all year. Kent Payne's "Super Rooster" (-19.5) opened the year with a victory at Cloverdale and diligently chased. But despite 10 top-threes of his own, Payne lost points to the leader in all but three appearances. Esdon Lehn return to the complete GN slate with "Diggin' Fever" (-33.5), and "Red Line Fever" (-110.5) missed only Rockwell in what was a carnage-filled year for the contenders. Steve Burge's "Lock-N-Load" (-153.5) missed Tomah and Hutchinson completely but returned to action in Iowa and steadily marched its way to fifth.
About National Tractor Pullers Association
The NTPA is the sport's oldest and most respected truck and tractor pulling sanctioning organization. Governed by a board of directors, the NTPA is managed by World Pulling International (WPI), an independently owned entity. Headquartered in Worthington, Ohio, the NTPA provides rules and regulations and the infrastructures required for organizations throughout the country to arrange truck and tractor pulls. The 2019 NTPA Championship Pulling Circuit was sponsored in part by Case IH, O'Reilly Auto Parts, Alliance Tire, Enderle Fuel Injection, MAC Trailer, Ag Protect 1, Shell Rotella, STOP-FYRE®, Cen-Pe-Co Lubricants, Columbus Diesel Supply, Heritage Iron Magazine, Stainless Diesel, Midwest Wheel Inc., the National Tractor Pulling Championships in Bowling Green, Ohio, PowerBore Cylinder Sleeves, Profab Machine Inc., the Budweiser Dairyland Super Nationals in Tomah, Wisconsin, and Riverside Engine Inc.
Watch the 14th season of "NTPA Championship Pulling" presented by Case IH: Tuesdays at 6:30 p.m. Eastern/5:30 p.m. Central. Encore performances appear on Mondays at 12:30 a.m. and 6 a.m. Eastern. RFD-TV is available on satellite through DirecTV (345), Dish Network (231), and AT&T (568) along with Spectrum/Time Warner, Brighthouse, Comcast, Charter, Suddenlink, Cox, and other cable providers. Check your current provider for details or visit the channel finder at www.rfdtv.com. Stream RFD-TV on the Country Club service: www.rfdcc.com.
NTPA Live Streaming produced internet broadcasts of 13 national events in 2019. Visit WatchNTPA.com to purchase on-demand access to individual events or the $299 Season Pass---that's less than $10 per session! NTPA Live Streaming's new interface includes "Live DVR" controls and adaptive bitrate technology to promote an interruption-free broadcast. Check the site for lists of streamed events and compatible internet devices.
Subscribe to the Official Magazine of the NTPA! The Puller brings you the best in NTPA news, stories, and related pulling information. Tractor Supply Company (TSC) carries The Puller and the PULL! Official Program and Souvenir Yearbook.
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For more information about the NTPA, visit our website, www.NTPAPULL.com, follow us on social media at our Facebook page (ntpapulling), Twitter (@NTPApull), YouTube (NTPApull), and Instagram (ntpa), or call the NTPA office at 614.436.1761.


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Interviews and video: OKC Philharmonic concertmaster Gregory Lee to be featured soloist for 2018-19 season finale
A version of this story appears in the Sunday Life section of The Oklahoman.
A finale for all seasons: OKC Philharmonic concertmaster Gregory Lee to be featured in season finale
The Oklahoma City Philharmonic will explore all four seasons in its 2018-19 Classics season finale.
"Vivaldi wrote over 400 concertos - so many - but 'The Four Seasons' is the most famous and recognizable," said Gregory Lee, the orchestra's principal first violinist. "This is the first time it's going to be played in our Classics series, which is amazing to me. … I just love the way Vivaldi is able to make the violin sound so virtuosic and brilliant but still in the baroque style. So, that's something that is definitely unique about this piece in a concert."
- Related to this story
- Video: OKC Philharmonic concertmaster Gregory Lee
The Oklahoma City Philharmonic's longtime concertmaster, Lee will take his place in the sun during Saturday night's performance as the soloist on "The Four Seasons." Music Director Alexander Mickelthwate has paired the Italian composer's iconic 1725 tone poem on the program with Brahms' "Symphony No. 1 in C minor."
"To highlight a piece's revolutionary character – like in this case, the Brahms first symphony – I like to then pair it with something much earlier. I could have done like a Mozart and Hayden, but in this case, I liked to go further out and have this kind of baroque angle … and then we create a contrast between the two," Mickelthwate said. "(Gregory is) a great player, and then he's just really, really helpful. He's a good leader."
Stepping into the spotlight
A native of Australia, Lee joined the OKC Philharmonic as concertmaster, a title given to the principal first violinist, 12 years ago, at roughly the same time he joined the music faculty at the University of Oklahoma.
"The concertmaster is sort of a role that has had a long tradition. I think before there was a conductor, the concertmaster would lead the orchestra. But now I serve as a liaison between the orchestra and the conductor, especially with the string section. I might help with doing bowings or letting the orchestra know which part of the bow to play in … and, of course, tuning the orchestra," Lee said. "I came here to teach at OU, teach violin, and the concertmaster opening happened to come up. So, I was fortunate to be able to audition for that the same year I came in."
While he loved working with the philharmonic's founder and music director emeritus Joel Levine, Lee said he is honored to be the soloist at final concert of Mickelthwate's debut season as music director.
"It's definitely very exciting. I don't do this very often, being a soloist, and it's great to be doing it in front of my own orchestra. … The orchestra is so supportive and kind and friendly, and I'm very fortunate to be able to be in an environment like that," said Lee, adding that his parents are traveling from Australia for Saturday's concert. "Alexander's often bringing in and playing pieces we've never done before or being a little more adventurous. I sometimes wonder, 'How's the audience gonna react?' But the audience seems to have really been accepting and really enjoy what we've done so far.
Playing an iconic piece
A pop culture favorite, Vivaldi's "The Four Seasons" has been adapted to jazz, techno, tango and rock stylings and featured in an array of ideo games, movie trailers and TV shows. Violin virtuoso Nigel Kennedy's 1989 recording of it with the English Chamber Orchestra in 1989 sold more than 2 million copies to become one of the best-selling classical recordings ever released.
"This piece can play in so many different ways. There's so many ways to interpret it," Lee said. "It's always trick to find a balance between wanting to play it in a style that has some reflection of performance practice - I think that's sort of been the trend that last 20, 30 years is to play it in some influence of how it was played back then – but also have a more contemporary, 21st-century take on it."
Even if the music is already familiar to them, Lee said he believes that concertgoers will be astounded with how much more powerful the "Seasons" are when experienced live.
"There's that sort of invisible interaction, I guess, that you feel with being a performer and also being in the audience. It definitely feels different performing for a full house, as we usually do get here, and hopefully the audience will also feel like it's a different experience than just turning on a CD," he said.
Oklahoma City Philharmonic featuring violinist Gregory Lee
When: 8 p.m. Saturday.
Where: Civic Center Music Hall, 201 N Walker.
Tickets and information: www.okcphil.org or call 842-5387.
Brandy McDonnell, also known by her initials BAM, writes stories and reviews on movies, music, the arts and other aspects of entertainment. She is NewsOK's top blogger: Her 4-year-old entertainment news blog, BAM's Blog, has notched more than 1... Read more ›