text:
Using VPN Services to Combat Internet Surveillance Using Deep Packet Inspection
Posted by amapuranga on November 5th, 2018
Internet users use VPN services for a variety of reasons, including bypassing restrictions or censorship, accessing entertainment services such as Netflix and to cover their tracks online. VPN services can mitigate against potential deep packet inspection of your communications by your Internet service provider.
Internet communications, whether sending an email, surfing the web or making a phone call using VoIP uses Internet Protocol (IP). In IP, the information you transmit is arranged in packets, each packet consisting of some header information and the main information being transmitted, known as the payload. The header consists of the origin information, including the IP address of the source, and the destination information which includes the destination IP address.
In shallow packet inspection, processors examine the header information of the packet to determine the origin of the packet, its destination and how best to route it to its destination. This is analogous to the postal system where the origin and destination addresses of a letter are required on the envelop. The letter can therefore be forwarded to the receiver or, if need be, returned to sender without the need to open the envelop.
In deep packet inspection, however, processors go beyond the header information and deep into the information being transmitted. Imagine your postmaster opening your letter to find out information in it and make whatever decisions based on that information. There are many reasons why your service provider may be interested in implementing deep packet inspection on data transmitted through their network. These include gathering information for targeted advertising, preventing spam and viruses, or in response to a law enforcement order to monitor your communications.
Deep packet inspection is routinely used to examine information, in real time, to detect certain phrases that may reveal criminal activity. For example, the word "Jihad" is sometimes monitored in communications by national law enforcement agents. Too many occurrences of the word from a single source could trigger a more focused monitoring of that source.
After the Boston Marathon bombing of 2013, the Russian Intelligence indicated that they had been monitoring one of the bombing suspects, Tamerlan Tsarnaev. Temerlan was reportedly notorious for posting jihadist messages on Facebook so it is conceivable that deep packet technology was used to monitor his behaviour on the Internet. The Russians also indicated that the word "Jihad" had been picked up when the suspect was having a conservation with his mother.
Unfortunately, the same deep packet inspection technology used to monitor criminals and terrorists can be used to rob law abiding citizens of their privacy. Intelligence officials, especially in repressive regimes, are known to use this technology to monitor online activities of political opponents and cyber-activists. It is well known that some African governments have acquired this technology from China under the guise of cybersecurity but the technology is oftentimes used for thwarting decent.
The use of VPN services such as those feauture on vpn-service.info are very cost effective solutions for keeping your communication on the Internet safe. The VPN client, installed on your computer, encrypts any of your communications before it is routed to the ISP. Without knowing the contents of your communications, the ISP forwards your information to the VPN server which decrypts it and forward it where it needs to go.
For the cost of a beer a month, you can ensure that your communication is encrypted and even your Internet provider does not know what you are communicating.Top Searches - Trending Searches - New Articles - Top Articles - Trending Articles - Featured Articles - Top Members
Copyright © 2019 Uberant.com654,335 total articles and counting.


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subset: commoncrawl


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Many smartphone users have been complaining of poor network connectivity during load-shedding this year.
Mobile networks have acknowledged that load-shedding can have an adverse effect on the functionality of their base stations, with operators telling MyBroadband that they "face an incredible challenge" when load-shedding takes place.
This can pose problems for users who purchase limited-time data bundles and are unable to make full use of their data due to networks going down.
For example, if someone purchases a daily data bundle while at work to use once they get home and experience connection problems once they arrive due to load-shedding, they may not be able to make full use of the data bundle.
Once its validity period has elapsed, the data is gone – regardless of the reason you did not use it.
MyBroadband asked South Africa's mobile networks if they had plans in place to deal with this potential problem or if they issued refunds to affected customers.
Cell C
Cell C said its network is affected by load-shedding just like all other business in South Africa, and advised customers to plan around scheduled power outages.
"Cell C makes every effort to ensure uptime on its network, however, as with all other businesses, we are in some cases affected by load-shedding," Cell C told MyBroadband.
"Customers are advised to check their load-shedding schedules and plan accordingly, but even if there is no power, it does not necessarily mean that they cannot use their data."
With regards to daily bundles in particular, Cell C said there should be enough time to use the data when the power is up.
"Additionally, daily bundles last for 24 hours, which should provide ample time for customers to make use of it outside of load-shedding periods."
A Vodacom spokesperson told MyBroadband that it dealt with all refund requests according to its guidelines.
"Vodacom has guidelines in place for network disputes and they are dealt with on a case by case basis," the company said.
MTN executive for corporate affairs Jacqui O'Sullivan told MyBroadband that it is impossible to determine whether unused data claims could be attributed to load-shedding.
"Refunds to customers are generally made as a consequence of an internal MTN fault that resulted in a service not being available," O'Sullivan said.
"While MTN is fortunately the network least affected by the current spate of load-shedding, due to its extensive investment in battery and generator back-ups, the company would simply not have the means to verify a customer's claims of unused data due to load-shedding."
O'Sullivan added that a similar argument could be made for DStv customers claiming refunds due to load-shedding.
"It could not be expected for DStv to compensate customers for hours of TV not watched, as a consequence of load-shedding," she said.
"These are complex and often frustrating times for South Africans."
MyBroadband reached out to Telkom for feedback but the company did not respond by the time of publication.


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Residence #1 Rehabilitation
- SCH Number
- 2019070571
- Lead Agency
- Parks and Recreation, Department of (California Department of Parks and Recreation)
- Document Title
- Residence #1 Rehabilitation
- Document Type
- NOE - Notice of Exemption
- Received
- Posted
- 6/28/2019
- Document Description
- Rehabilitate the dilapidated California Conservation Corps era Residence #1 to restore and repair damaged materials including sheetrock and roof, replace heater. hand railing, flooring and bathroom fixtures, and repaint interiors of residential units at Calaveras Big Trees State Park. See NOE for full description of project.
- Contact Information
Heather M. Reith
Department of Parks and Recreation
22708 Broadway Street
Columbia, CA 95310
Phone : (209) 536-2887
- Counties
- Calaveras
- Other Location Info
- Calaveras Big Trees State Park
Notice of Exemption
- Exempt Status
- Categorical Exemption
- Type, Section or Code
- Reasons for Exemption
- Project consists of repair and maintenance of existing public structure involving no expansion of use beyond that currently existing; conversion of existing small structures from one use to another where only minor modifications are made to the exterior of the structure; and minor public alterations in the condition of land which do not involve removal of healthy, mature scenic trees; and maintenance, repair, stabilization, rehabilitation, restoration, preservation, conservation, or reconstruction of historical resources, in a manner consistent with the Secretary of the Interior's Standards for the Treatment of Historic Propertim; with Guidelines for Preserving, Rehabilitating, and Reconstructing Buildings (1995), Weeks and Grimmer.
- Notice of Exemption
Disclaimer: The Governor's Office of Planning and Research (OPR) accepts no responsibility for the content or accessibility of these documents. To obtain an attachment in a different format, please contact the lead agency at the contact information listed above. You may also contact the OPR via email at email@example.com or via phone at (916) 445-0613. For more information, please visit OPR's Accessibility Site.


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Fox Jewelry Factory Co. Ltd – Small Orders Online Store – More Jewelry on
1. Away from chemical — Longe de química
2. Take off when taking bath — Retire quando tomar banho
3. No striking — Não bata
4. No wearing when doing exercise — No vestindo ao fazer exercício
5. Take off when sleeping — Retire quando dorme
6. Cleaning with soft cloth — Limpeza com um pano macio
Currently, you can pay using Boleto, Visa, MasterCard, QIWI, Western Union, Maestro debit card, WebMoney and bank transfer. More payment options will be available on AliExpress in the future.
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(From left): MSM CFO Ab Aziz Ismail, MSM group CEO Datuk Khairil Anuar Aziz, MSM chairman Datuk Wira Azhar Abdul Hamid and MSM director Datuk Haris Fadzilah Hassan at a press conference after the group's annual general meeting here today. Photo by Patrick Goh/The Edge
Azhar: One of the appeals that we are making and will continue to make to the government [is that] whichever decision that is made as far as the sugar industry is concerned, it has got to be done on an equitable basis. Patrick Goh/The Edge
KUALA LUMPUR (June 19): Refined sugar producer MSM Malaysia Holdings Bhd has warned that it will resort to taking commercial approaches that may not be beneficial to Malaysia as a whole, should the group's financial performance continue to be impacted by sugar import permit holders that are approved by the government.
Group chairman Datuk Wira Azhar Abdul Hamid told a press conference today after MSM's annual general meeting that the two local industry players have constantly engaged with the government to express concerns and for their views on approved permits (APs) to be taken into consideration.
"If this situation is not managed well, we will probably have to resort to other alternative strategies that would be positively beneficial to MSM without taking into account national interest or Malaysian consumers' interest.
"One of the appeals that we are making and will continue to make to the government [is that] whichever decision that is made as far as the sugar industry is concerned, it has got to be done on an equitable basis," said Azhar.
According to Azhar, MSM has an installed production capacity of 2.25 million tonnes, including the group's latest refinery in Tanjung Langsat, Johor. The plant, which was physically completed in July 2018, still runs at a utilisation rate of 30% in view of the current market surplus.
Together with Malaysia's other sugar player, Central Sugar Refinery, there is adequate capacity to serve the domestic demand for sugar, estimated at 1.6 million tonnes annually, he added.
However, the APs issued by the Malaysian government expose local refiners further to the global sugar market surplus, as excess supplies from producing countries such as Thailand are being directed into the Malaysian market, Azhar said.
"We are not burdening the government, we try our best to complement the government's objectives and we understand where the government wants to go.
"We seek the government's understanding to help us — not by subsidising our business — but to ensure that we can maximise our potential in, especially, the domestic sugar market," he stressed.
At 3.20pm, shares in MSM were unchanged at RM1.43, for a market capitalisation of RM1.01 billion.


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Craeft: How Traditional Crafts Are about More than Just Making [EPUB]
02 November 2017, 22:54
In the modern world we are becoming bombarded by craft. Hand-made tools, artisan breads and craft beers are all part of a pantheon of goods designed to appeal to our earthier selves, our sense of tradition, quality and luxury, all brought together through a personal touch - objects to savour in a world of meaningless mass manufacture.
But once, craft - or more specifically, cræft - meant something very different. When it was first written down in Old English, over a thousand years ago, it had an almost indefinable sense of 'knowledge', 'wisdom' and 'power'. To be cræfty was to be truly intelligent - but in a way that is almost inconceivable to us today.
Through a series of mini-histories, detailed craft analyses and personal anecdotes, archaeologist, historian and broadcaster Alex Langlands goes in search of the lost knowledge of cræft.
Fusing stories of landscapes, personalities and mesmerising skill, with back-breaking hard work, this book will convince readers - for their health, wealth and well-being - to introduce more cræft into their lives.
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Track & field: E-N Area Athletes of Week, April 18
BOYS — Bailey Henderson, New Braunfels Canyon: Senior cleared 16 feet, 7 inches in the pole vault to win the District 25-6A championship on Wednesday at Rutledge Stadium. The clearance was 1 inch short of the Greater San Antonio area record.
GIRLS — Olivia Pappas, Smithson Valley: Senior won the 100- and 300-meter hurdles on Thursday during the District 25-6A championships at Rutledge Stadium. Won the 100 hurdles in 14.55 seconds and the 300 hurdles in 43.79. Both times are area bests this season.
To nominate athletes, coaches may email firstname.lastname@example.com.
Photo: Marvin Pfeiffer /San Antonio Express-News


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ONE hundred motorbikes roared into a Sway care home as part of a special surprise to mark the 100th birthday of resident Jean Broadley.
The spectacle at Gracewell care home was organised by Jean's son John and his partner Sylvia Walker to celebrate the milestone. "It is a very emotional experience when something like that is arranged," Jean told the A&T through tears. "They told me to be ready and dressed, and said something is happening.
"I went out the front door and saw something through the trees towards the entrance; I think I said something like, 'Oh no!', and there was a roar of bikes. I didn't want a fuss!"
Bikers who took part in the event on Sunday came from local clubs, including Blackfield and as far afield as Portsmouth. They wore turquoise ribbons on their machines, Jean's favourite colour, and each carried a rose they presented to her.
The bikers then joined care home residents and Jean's relatives for a special cream tea celebration, with 160 people in all toasting her birthday. Jean had turned 100 on Tuesday, when she went out with John and Sylvia to the Grand Harbour Hotel in Southampton.
The bike tribute was slightly tongue-in-cheek, since when John was young Jean banned him from having a motorcycle because she believed the machines were dangerous. She also did not want him associating with the mods and rockers in fashion at the time.
"Back then bikers had a bad reputation, but nowadays things are totally different," Jean explained. "They do a lot of good work and I was overwhelmed."
John now owns a bike and Sylvia is a proud biker from the Waterside who has been a member of various associated clubs.
Born in Cheshire, Jean says she has led a "very lucky" life; having only spent two nights in hospital when she delivered John.
However, she did suffer heartbreak aged just 17. Her father, a senior engineer, died after fumigating a boat; he went back onto the ship to sleep but a pocket of cyanide gas was left in his bunk.
As a young woman, Jean went to business college before working for Liverpool City Council. "It was for the princely sum of 17 shillings and six-pence a week," she said.
Jean later changed roles, working as a secretary in the offices of film company Metro- Goldwyn-Mayer. "In those days cinemas rented films and the film company had to send a salesman out to sell a film to the cinema before going back to the branch," she said.
When the war started in 1941, Jean faced being conscripted, but married Noel, an accountant, the following year in a small, intimate ceremony in west Kirby, on the Wirral.
She did not see Noel for the next four years, when he went off to war serving under Montgomery and fighting in the North African and Italian campaigns.
She said he came back a "changed man" in 1946. "He was thin and I hardly recognised him – and they said he looked much better than he had been," she said. "He was a good man; he was loyal and hardworking."
Noel and Jean were married for 68 years before his death, and lived in the same house for 56 of those. John is their only son.
"The younger generation will never know what the older generation went through – if there's another war there'll be a button pressed and that will be it. There won't be the bombing that we had.
"In Liverpool we were right near the docks – there'd be bombing five, six or even seven nights of the week and it wouldn't just be one house it would be a while load of houses blown up."
She also remembers the rationing, adding: "After the war ended the first thing we bought was a new vacuum cleaner – everything was second-hand during the war."
Jean was a housewife after her husband was demobbed and led an active social life, playing bowls and joining the townswoman's guild, acting as its president for a spell.
Since moving to the New Forest around nine years ago, Jean has enjoyed her time at Gracewell, where she plays Scrabble, does crosswords and takes part in its quizzes.
A long-term passion of Jean's is poetry, which she has been writing for the past few decades. She has penned more than 100 pieces on a range of themes, including ladies bowling, her late husband and going to lunch.
"I love writing poetry and being able to express myself," she added with a smile.
As for her philosophy on life, Jean reveals: "I think there is too much publicity printed in the newspapers. I do not want to hear about everybody's sordid life and what they are doing, it scares me. I think about children growing up with phones stuck to their hands.
"I do like to see higher standards of morals, and peace for everyone. I think a lot of it comes down to greed – I have never been a greedy person," she continued.
"I can remember – I must have been five or six and at school – we were given books to copy for our writing. It stuck in my mind, and I have never forgotten it, that if something is worth doing it's worth doing well. That's what I have strived to do."
Asked for the secret to a long life, she replied: "Loyalty; loyalty to your family, loyalty to each other and to be grateful. Be grateful for what you have. I am most grateful for everything."


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A Change of Season
A Change of Season
Her spectacles had slipped down her nose and her pepper and salt curls danced about. She announced:
"I call on Comrade Brainin to speak next. Comrade Koroteyev will speak after him."
Dmitry Koroteyev slightly raised his thin dark eyebrows in an expression of surprise. Yet he knew that he would have to speak at the readers' meeting. The librarian had asked him well in advance and he had accepted.
Everybody at the factory treated Koroteyev with respect. The director, Ivan Zhuravlyov, had recently admitted to the secretary of the Party Town Committee that without him the release of the new precision-cutting tools would have had to be put off to the following quarter. Nor was Dmitry valued only as a brilliant engineer--people were impressed by his many-sided learning, his intelligence, and his modesty. Even Chief Designer Sokolovsky, who was known for his sharp tongue, never said a word against him. As for the librarian, who had had a discussion with him about literature, she told everyone: "His feeling for Chekhov is unique." It was evident that the readers' meeting, for which she had worked more than a month like a schoolgirl for a stiff examination, could not possibly be held without him.
Engineer Brainin spread a pile of papers on the table. He spoke too fast, as though frightened of not having enough time . . .


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Datopsys is a technology based startup founded by a team of IIT and IIM graduates.
Our focus is on product development and we are launching a content based application for the Indian market. It will be a web and mobile application aimed to bring knowledge and entertainment together which will change the way people view and consume the content.
We are currently Hiring aggressively for positions of content writers and mobile developers.


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Our client is a multi-award winning, market leading agricultural manufacturer who are recognised globally. They're looking for a validation engineer to join them to work on a new project which involves the integration and validation of embedded systems in a new vehicle project. They're offering a 6 month contract with an opportunity to extend.
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Consultant: Stefene Balende
Contact number: +44 2 030 533 722 / +44 2 075 494 042


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2nd Grade Kindness
In second grade my friends and I were playing tetherball. A kid was being rude to my of my friends saying stuff like, "you suck", and "your stupid." He was saying all this super rude things about her. She told me what he was saying and that it was making her upset. I went over to him and said, "Stop saying rude things to (her name). She is very upset and you are being rude." My friend told my teacher that I stood up for her after he said all the mean things. My teacher gave me a be kind bracelet and I was elected student of the month. My mom and teacher were very proud of me.
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NFkB activation regulates a certain number of genes which are required for physiological T-cell response. These include IL-2, IL-6, IL-8 genes as well as a number of receptor genes (Fig. 5.1). There is evidence that the intracellular redox condition is a very important regulator of NFkB function. ROS have been denoted as universal second messengers of the T-cell signalling cascade, which can activate NFkB [46,93-95]. However, oxidation is unable to fully activate NFkB in T-cells without interference from other inducers. It seems as if oxidation is important for the phosphorylation and degradation of the IkB inhibitor while the reduced state is essential for NFkB DNA binding.
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Dunes, Desert Elephants and Nomads
From the dunes of Sossusvlei to the Skeleton Coast and utterly remote Serra Cafema
Personalised journeys from start to finish
Save an acre of rainforest each time you travel
Every detail taken care of
At a glance
This is a proper African adventure exploring the most remote and breath-taking landscapes in Namibia while staying at some of its finest luxury camps.
After a night in the modest capital, Windhoek, fly out to the iconic red sands and twisted trees of Sossusvlei where you can climb some of the highest dunes in the world and marvel at the often surrealist vistas.
Next head to Hoanib Skeleton Coast Camp, an oasis of comfort in the middle of a vast desert. Head on out game drives in search of desert elephant, lion, giraffe and oryx, or head to the rocky shoreline to get an earful of the noisy Cape fur seal colony among the bones of whales and shipwrecks which gave this region its name.
Heading further north still to the somehow even more isolated Serra Cafema which sits alongside the Kunene River which acts as the border with Angola. A rare source of water, it supports wildlife such as crocodile, zebra and a surprisingly rich array of birdlife, as well as the nomadic Himba people who you'll get to meet as you become one of the few people to have explored this corner of Africa.
Example Trip Itinerary
After landing at Windhoek's International Hosea Kutako Airport, you will be welcomed by our representative who will discuss the details of your safari with you. After your briefing, you will be introduced to your pilot before boarding your scheduled light aircraft flight to your camp.
Private transfer from Windhoek airport to Windhoek hotel
Accommodation in Windhoek
- Seven suites
- Bar and lounge
- Swimming pool
- Restaurant
- Wi-Fi
Your home before you venture off into the barren and beautiful Namibian Desert, this stylish boutique hotel is hidden away in the Eastern corner of Namibia's capital and only proclaimed city, Windhoek. The city itself is the seat of the country's cultural and administrative powers but despite this, it remains one of the smallest capitals in the world with just 250,000 residents. The Olive reflects Windhoek's small size, providing a cosy but luxurious bolt-hole with great access to the surrounding wilderness. Reminders of the prevalent Namibian culture are spread throughout the hotel as the modern is combined with the traditional. Rough-hewn wooden benches sit on plush carpets around sculpted granite coffee tables, animal-skin rugs lay beneath large beds covered in crisp white cotton and wide glass doors lead out onto your personal terrace for a view across the small city.
- 7 Luxury Rooms
- 1 Luxury Family Unit
- Free WiFi
- Swimming Pool
Named after the famous explorer Sir Francis Galton, this small hotel has a relaxed but efficient style which creates a very welcoming atmosphere. Impressive wildlife photography adorns the walls whilst the rest of the interior is a combination of modern minimalistic and understated chic. A mere ten minute drive from the centre of town and perched on the edge of Windhoek's northernmost affluent suburb of Eros, guests staying here will be ensured of peace and tranquillity. There is Wi-Fi throughout the property and the eight guest rooms all have wired internet connectivity and satellite television. The communal areas are really comfy, especially after a long international flight and consist of a large lounge, indoor and outdoor dining areas, a swimming pool as well as understated garden areas. There is also a delightful 'al fresco' dining area by the pool where freshly prepared and very tasty meals can be served (including lunch and dinner). There are also a number of shops, restaurants and supermarkets within easy striking distance – a real gem to have as a base when staying in the capital.
Windhoek is one of the smallest capital cities in the world with a population of just 234,000, but it is home to some fascinating buildings with typical German architecture. You could also visit the National Botanical Gardens which has the densest stand of mountain aloes in Namibia. The restaurants in town are good with delicious game meat on offer to those who fancy trying it.
Transfer to Windhoek airport
Light aircraft flight to Sossusvlei
Accommodation in Sossusvlei
- Eleven self-contained villas, each with private pool
- Air conditioning
- Lounge
- Dining area
- Wine cellar
- Library
- Craft boutique
Offering more of a 'boutique' polish and size set in the 37,000- hectare private Kulala Wilderness Reserve, and a stone's throw from the Sossusvlei dunes, this beautiful lodge is easily the most luxurious in the area. Little Kulala consists of eleven self-contained 'kulalas', sympathetically designed so as to merge deceptively into the desert landscape. Each one is air conditioned with an en suite bathroom, and has its own private outdoor pool and shower. The rooms are huge and with floor to ceiling windows designed to spoil you with the incredible views that flood in. Or take it a step further and sleep under the stars on your own rooftop 'skybed'. The main lodge is built on three levels and provides an elegant entertainment area, with a spacious lounge, stylish dining area , well-stocked reference library and its own wine cellar to boot.
- 25 en suite kulalas
- Dining room
- Lounge (with computer for internet access)
- Pool
- Stargazing deck
Located within the 37,000 hectare private Kulala Wilderness Reserve, this lodge enjoys convenient access via a private gate to the iconic red dunes of Sossusvlei. Staying here is extremely comfortable, with 25 thatched and canvas "kulalas", each on a raised platform to catch the cool desert breezes and with private rooftop decks should you want to spend the night under the spectacular star-filled skies. All are en suite, and solar powered heaters provide hot showers. The main lodge is a clay construction with a North African inspired décor, and it's here you enjoy the simple yet delicious meals in the spacious dining area followed by relaxing in the comfortable lounge. There is also an outdoor plunge pool and stargazing deck from which to enjoy the breathtaking scenery.
- 10 desert villas
- Star-viewing skylights
- Swimming pool
- Safari Shop
- Observatory with professional astronomer
Cradled against the ancient mountains, Sossusvlei Desert Lodge is renowned for its desert experience with luxurious accommodation overlooking the stark yet beautiful Namib Desert. Designed to capture the splendour and solitude of the desert, just ten stone and glass desert villas spread out along the curve of the escarpment allowing absolute privacy. Each air-conditioned suite features a private veranda, split-level bedroom and living room with fireplace, en-suite glass-encased bathroom and outdoor shower. The villas are equipped with a stunning star-viewing skylight, discreet CD system, custom-stocked personal bar and compact spotting scope for magnificent star and game viewing. The guest area, where walls have become windows that fold away completely, boasts unimpeded desert vistas. The split-level Lodge features a fire-lit bar, comfortable sitting room, swimming pool, wraparound verandas and a Safari Shop. A fine selection of wines from an impressive walk-in wine cellar complements delicious Pan African meals. Guests can escape the desert heat with a revitalizing midday dip in the pool fed by water from an underground spring. At sunset, animals are drawn to a nearby waterhole, enhancing desert sundowner drinks.
- 23 Dune Chalets
- Two Honeymoon Chalets
- Swimming pool
- Restaurant and bar
Lying just 4km (2.5 miles) from the Sesriem gate, at the base of a mountain, Sossus Dune Lodge is the first and only lodge inside the century-old Namib Naukluft Park. Linked by a raised wooden walkway to the left and right of the main communal building, 25 wood, canvas and thatch chalets enjoy expansive views over the dunes, mountains and Sesriem Canyon. Being inside the park, guests can be at the great rust-red dunes of Sossussvlei for sunrise and be the first to climb some of its towering neighbours, and stay until after sunset, when the light is most spectacular. There are also nature drives to see the incredible desert adapted wildlife and guided walks.
Populated with some of the world's highest dunes, all set beneath a deep blue sky, no self-respecting Namibian safari would be complete without a visit to the awe-inspiring Sossuvlei. Spend your days here exploring the desert sands on foot and by quad bike. When you're back at your accommodation, have some drinks and watch the sun set in one of the world's most striking locations.
Head out to Sossusvlei and Deadvlei together with your guide. Deadvlei is a white clay pan near the salt pan Sossusvlei inside the Namib-Naukluft Park. The area is dotted with dead camel thorn trees which are estimated to be about 900 years old but haven't decomposed due to the dry climate.
Fly north up the coast in a light aircraft accompanied by spectacular views of Damaraland, the desert and sea from the air.
Hoanib Skeleton Coast
Accommodation in Hoanib Skeleton Coast
- Seven twin-bedded suites and one family unit
- Shaded, private outdoor decks
- Laundry services
Placed at the confluence of two tributaries in a broad valley of the Kaokoveld Desert, the camp offers an unforgettable gateway from which to experience both the thrillingly desolate Skeleton Coast and the private Palmwag Concession, alive with desert-adapted wildlife. You'll get a feel for the exclusivity and wonderful remoteness of your accommodation as you fly in by light aircraft – the only way to access the camp. The imitate, luxury tented camp consists of just seven twin-bedded suites and one family unit, each complete with shaded outdoors decks from which to contemplate the valley's starkly stunning, moon-like landscape. Scenic flights over desert shores reveal lonely shipwrecks, massive dunefields, floodplains and the Auses Spring. Explore the Hoanib Riverbed for sightings of elephant, lion, giraffe, gemsbok and springbok, shaggy brown hyaena and opportunistic black-backed jackal, or head to the rocky shoreline to get an earful of the noisy Cape fur seal colony. Unravel the mysterious history of the original ancient Strandloper people and the enigmatic stone circles they left behind and encounter the Welwitschia on a nature walk – one of the oldest and strangest plants on the planet.
Placed at the confluence of two tributaries in a broad valley of the Kaokoveld Desert, the camp offers an unforgettable gateway from which to experience both the thrillingly desolate Skeleton Coast and the private Palmwag Concession, alive with desert-adapted wildlife. Explore the Hoanib Riverbed for sightings of elephant, lion, giraffe, gemsbok and springbok, shaggy brown hyaena and opportunistic black-backed jackal, or head to the rocky shoreline to get an earful of the noisy Cape fur seal colony. Unravel the mysterious history of the original ancient Strandloper people and the enigmatic stone circles they left behind and encounter the Welwitschia on a nature walk – one of the oldest and strangest plants on the planet.
This fascinating 4x4 trip to the coast takes you via the wilderness and wildlife of the Hoanib River and floodplain, the dune fields and Klein Oasis, while the Skeleton Coast itself reveals a rocky coastline with its huge Cape fur seal colony and a few shipwreck remains. Weather dependent, a scenic flight back to camp offers a magnificent perspective of your journey from the air.?
Light aircraft flight to Serra Cafema
Kunene River
Accommodation in Kunene River
- 7 Luxury Canvas Tents
- 1 Luxury Canvas Family Unit
- Ceiling Fans in each tent
Serra Cafema is located in the extreme north-west of Namibia on the banks of the Kunene River in the Hartmann Valley. Undoubtedly amongst the most remote camps in Southern Africa, Serra Cafema is only reachable by light aircraft which adds to the exclusivity of this beautiful property. Serra Cafema is an intimate, peaceful camp with a unique mix of rustic and luxury elements nestled amongst the shady Albida trees on the banks of the Kunene. Rapids just below camp provide a calming ambiance with guests often lulled into dreamland by the gurgling waters after a day exploring one of the driest, starkly beautiful regions in the world. Accommodation at Serra Cafema consists of eight riverside Meru-style canvas and thatched villas on spacious, elevated decks blended smoothly into the picturesque surroundings. Each fully furnished tent has an en-suite bathroom, ceiling fan and mosquito nets. A late afternoon spent lounging on the front deck soaking up the breathtaking vistas of this contrasting wilderness is an absolute must.
Enjoy your days in the stunning Serra Cafema region, in the oasis of this mostly desolate and arid region, one of the remotest places on Earth, with nature drives, guided walks and even visits to the local villages of this extraordinary nomadic Himba people.
Light aircraft flight to Windhoek International
Get in Touch
Dunes, Desert Elephants and Nomads
How We Work
We create fully personalised trips from start to finish, working with you to pick locations, accommodation and guides that suit you.
Each time you travel with us, you preserve an acre of precious rainforest through our partnerships.
From in-depth private tours to restaurant reservations, we take care of every detail so you can make the most of your journey.


text: I haven't been posting a lot have I? I think the dates can speak for themselves, but I have been EXTREMELY busy this week and it's not letting up. *Tears* Seriously, somebody do my projects for me!! Then I'll be able to blog everyday like back in the day!! *Crickets* Well, I understand, but let's get into this birthday post. Big names and big groups are in this post! Yes, I'm talking to the Exotics! Continue reading


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Hewlitt Packard dropped the price on their tablet all the way down to 99 bucks. That sounds like a great deal and it is. However HP has had a lot of trouble moving their not-ready-for-prime time tablet in the last two months and they've already DISCONTINUED the product after a brief 2 month run.
HP announced they are dropping their PC, phone, and tablet ambitions entirely. So just know that if you purchase their tablet, you are buying a DEAD PLATFORM.
Of course, HP might sell their consumer business to someone... I would imagine that some company out there would love to control the patent portfolio that includes the ones that cover WebOS. Even if a buyer never puts any more development into WebOS or Palm's stuff, I bet they would be valuable to Google or MS just to help protect them from other patent trolls.
Be careful if you intend on buying the HP Touch Tab
Found a good deal on the interwebs and want to share? Post it here!
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- Brewmaster
- Posts: 3289
- Joined: Thu Dec 01, 2005 6:27 pm
- Cash on hand: Locked
- Custom Rank: Billions and billions eaten.
- Location: Verbosity, USA. Population Me.
Be careful if you intend on buying the HP Touch Tab
Just past the line of sanity ^.
Just past the line of sanity ^.
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Statement by Attorney General Doug Downey on Delivering Construction Industry Prompt Payment on Time
Today, Doug Downey, Attorney General of Ontario, issued the following statement:
"Our government is pleased to announce the full implementation of Canada's first-ever prompt payment regime and a new, streamlined dispute resolution process that will cut red tape to support jobs and growth in Ontario's construction industry.
Ontario is open for business and open for jobs, and these industry-leading changes demonstrate our government's commitment to restoring our province as an economic powerhouse.
Effective today, subject to transition rules, these changes to the Construction Act will help prevent payment disputes from delaying work on construction projects, speed up the payment process and reduce time and money spent on litigation. This will ensure workers and businesses are paid on time and disputes are resolved quickly.
We would like to thank Ontario's construction sector for sharing their expertise and continued support as we work together to grow jobs and the economy in our province. Today marks a new and prosperous era for our construction industry and thousands of businesses, workers and their families."
"ADR Chambers commends the Government of Ontario for fully implementing Canada's first-ever prompt payment and adjudication regime. This industry-leading initiative puts in place a new process for settling payment disputes in a timely, cost efficient way – allowing workers and businesses to keep construction projects on schedule. ADR Chambers is honoured to have been selected as the Authorized Nominating Authority and we look forward to drawing on our experience to oversee the adjudication process for dispute resolution under Ontario's new prompt payment and adjudication framework."
Allan Stitt
"The Ontario General Contractors Association applauds today's implementation of a prompt payment and dispute resolution process in the province. The construction industry has been calling for a solution that addresses payment challenges for years, and the new prompt payment regime brought in by the Ontario government will ensure all parties are paid on a timely basis."
Clive Thurston
"Prompt Payment Ontario and all of its members thank the government for holding fast to making prompt payment and adjudication a reality. We have worked for over a decade to bring attention and action to the issue of delayed payments and their impact on Ontario's small businesses and the families they support. The government's changes to the Construction Act and implementation of the prompt payment and adjudication framework will result in a more efficient and productive industry. A stronger construction industry means a stronger Ontario economy that is open for business."
Sandra Skivsky


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jeff.young needed a new book or magazine design and created a contest on 99designs.
A winner was selected from 11 designs submitted by 6 freelance designers.
Nonfiction/academic book publishers
Textbook interior layout/typesetting with index (index page numbers to be supplied by publisher) There are no tables, charts or images, but numerous block quotes and subheadings. Please supply final design files in native layout format and both PDF and ePub formats.
Book Title: Dramatic Analysis: A Reader on Western Drama
Sample MSWord manuscript file attached (187 pages taken from actual manuscript)
Total number of manuscript pages: approx. 485 pages
Charts, tables or images: None. But numerous block quotes and sub headings
Layout page trim: 6"x9"
Output files required in both PDF & ePub formats.
Output 1: PDF should conform to PDF/X1a 2001 or PDF/X3 2002
Output 2: ePub format for iTunes distribution.
See URL below for PDF printing file specs.
Book Synopsis:
This is a combined play-analysis textbook and course companion that contains 22 essays on major playwrights from the European and American theaters: among them, Ibsen, Shaw, Brecht, Strindberg, Pinter, O'Neill, Williams, Miller, Mamet, Molière, and Shakespeare. Supplementing these essays there is a critical apparatus consisting of A Step-by-Step Approach to Dramatic Analysis, a list of Bibliographical Resources, a Glossary of Dramatic Terms, Study Guides, Topics for Writing and Discussion.
AuthorBioText: R. J. Cardullo's essays have appeared in such journals as the Yale Review, New Theatre Quarterly, and Modern Drama. He is the author, editor, or translator of a number of books, among them A Critical Edition of Two Modern Plays on the Dramatic Character of Sir John Falstaff; Theater of the Avant-Garde, 1890-1950; The Theater of Fernand Crommelynck; German-Language Comedy: A Critical Anthology; and What Is Dramaturgy? (which has been reprinted three times and has been translated into Spanish). A Phi Beta Kappa graduate of the University of Florida, Cardullo took his master's degree from Tulane and his doctorate from Yale.
Sample layout styles of similar type textbooks (For reference only, please submit updated and improved design.)


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my friend jordan has been frustrated by my lack of blogging lately, and has decided to ghost write for me. so here's my life according to her:
Dear diary,
Today I went to my interpreting class at Southeast community college. It was pretty fun. We had a break in the middle, because the class is super long. I got this really awesome burrito from a vending machine in the basement. It's super cool because it's a vending machine with frozen things, but dont worry becuz there is a microwave. I guess I'm learning stuff; the teacher has a masters and really knows her stuff! i wish that one day i could know as much as she does and help others to learn it too.
After class I'm gonna watch the the Nebraska game (GO BIG RED!--for those of you that don't live in nebraska, that's what we chant, because they wear red). I'll probably watch it with my mom. I hope she makes little smokies. they are really good. last time she added cheese to the barbecue sauce, and it was pretty good. but randy kept farting! EWWWWW!
well, guys, i hope you liked the update. sorry it took me a month. i've been spending a lot of time chatting and stuff. i'll post some pictures of my new haircut when i can get dad to show me how to use his digital camera.
okay, GO BIG RED! (now you know what that means! hey, maybe i am a teacher!).
13 November 2006
1 comment:
- Kansas City Star said...
¡Vaya Grande Rojo!
- November 14, 2006 7:25 PM
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text:
Item-Num.: CS9999
Foulard Print Silk Tie in Navy Blue
Product Details
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SEEKINGVocalist, Electronic Music.
Producer / writer seeking female singer / vocalist / writer who is able to provide good quality acapellas for online collaboration with a view to producing original album. No pressure, no time commitment and no time wasters (!) but a good level of commitment would be fantastic. Music should be fun.
More mature but don't let age put you off. The imagination, experience and the right equipment are marvelous.
ramseysounds @ g m a i l [dot] c o m
- Screen name:
- Ramseysounds
- Member since:
- Apr 02 2017
- Active within 24 hours
- Level of commitment:
- Committed
- Years playing music:
- 35
- Gigs played:
- Under 10
- Tend to practice:
- More than 3 times per week
- Most available:
- Nights
Depeche, Yazoo, PSB, Human League, Erasure, OMD, Goldfrapp, Chvrches, Tears for Fears, Clean Bandit, EBTG, Bat for Lashes and many more
Instrument experience:
- Keyboard:
- Advanced
- Electronic Music:
- Advanced
Cubase, lots of modern plug ins and my imagination.
Emma Harrop - Bad Books
Emma Harrop - Bad Books Year: 2019 Genre: Electronic
Another track reworked using just the original vocal stem and new electronica music
Bonnie Legion - Sticks n Stones
Bonnie Legion - Sticks n Stones Year: 2019 Genre: Electronic
My remix of a track originally written by Bonnie Legion, using just the vocal stem and featuring new electronica music.
Jo Engel - Except Now
Jo Engel - Except Now Track number: 1 Year: 2019 Genre: Electronic
So I took Jo's original piano ballad and turned it into this!
Fleur - Blind
Fleur - Blind Year: 2019 Genre: Electronic
My remix of Fleurs original track using just the vocal stem


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Amused by the shininess of a diamond, we ignore the fact that it is ultimately just a rock, and not worth its price. I call that the "ferret mentality".
Our society has become so commercialized and consumerist, that too many people are more focused on the medium than the message.
In a very literal sense, the medium is NOT the message.
Too much attention and effort are given to promotion, processing, presentation, protocol and procedure. Marketing, advertising and selling... symbolism over substance.
Pomp and circumstance. All sound and fury, signifying nothing.
We would be wise to realize that the packaging is not part of the product.
Our creative work is often and carelessly transformed from a project into a product. Foolishly, we`ve allowed the material to matter less to us than its marketability and appearance. "Appearance is everything" is deceptive nonsense we too easily and casually accept.
Instead of letting things stand on their merit, we prop them up with superficial and artificial imagery.
How crass. You would dismiss the most interesting man in the world...? just because he isn`t extravagant in clothing or manner? It`s easier, but lazy, to judge a book by its cover instead of content. We don`t necessarily lack vision, but haven`t bothered to look.
Short sighted and small mindedly, many expect conclusions and artifacts handed to them, fully formed and explained upfront, impatiently unwilling to work or ? wait for it.
The significance of artistic integrity is frequently underestimated and undermined... sacrificed or compromised for expediency and business concerns; as well as political and psychological posturing.
Artistry should be cherished and fostered, not perished and squandered.
What is actually important is not selling power, but telling power.
A shame "and a sham "that our culture expects us to "sell" ourselves and our work-- ingratiating ourselves through an inane masquerade aiming to convince others to "buy" us.
I`m an artist-- not a publicist, businessman or ringmaster.
I publish a book not to sell it, but to create ? to offer.
I have no interest in fame and fortune, nor the politics and pandering of "business".
None of that has anything to do with my writing.
Whether you read my book or not is your choice; buying is your responsibility. I`d rather not talk or trick you into buying Paradox: Journey Inside Out. The work speaks for itself, if you listen. You will either appreciate it, or you won`t.
I only show my artistic work to the world at all as a means and intention of contributing something awesome, interesting and meaningful to the world. Not to bring attention to me, but to my creative expression. Don`t make the mistake of confusing the messenger (medium) with the message.
Dare to look beyond the surface image or the moment to see not just what is, but what can be... what`s to come.
How unfortunate and negligent it would be to dismiss a great artistic project simply because it isn`t commercially processed, packaged and promoted in mainstream media trappings.
For More Information: http://www.myspace.com/exastral` target=_new>www.myspace.com/exastral.


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Since a decade, I have been crafting colorful, fun-filled and trendy Nabee socks. My style of socks started with a good night thought when I was working as a nurse. I had been selling Beanie Babies on eBay when I was in the 6th grade (Believe it or not, Beanie Babies paid for my freshman year of college). It was when it all began. I figured out that my love for designing out-of-the-box compression socks resulted in unique and effortless pieces which were appreciated by many. I decided to give entrepreneurship a try.
At a very early age, I started a Kick starter campaign to raise some money and make my dream come true. I was shocked when the campaign made nearly $13,000 with the help of 253 generous people. Initially flying blind and putting in 70-hour weeks, I was continually encouraged by the amazing responses from all of my fans. And finally, with the incredible support from everyone, 'Nabee Socks' paved its way amidst all hurdles to be where it is now.
Today, Nabee socks are sold around the world and have won the hearts of millions of people. Be a part of the Nabee family and dance to the tune of your dreams!
Nabee Socks was born out of the idea of creating a unique and playful blend of stylish, comfortable, and poppy pair of colorful compression socks full of joy and fun. Our super soft top-quality Nabee Comfort Blend is designed to complement your happy feet with a classy look. Get your pair of Nabee Socks and rock on! All Nabee Socks are made with the 'art of the soul'. We gear up your feet with a sense of confidence. If you're looking for the perfect combo of fashion and comfort, Nabee is the place to be. Yes! You heard it right. Let's check out!
Nabee's compression socks provide your precious lower extremities with enhanced blood circulation by gently hugging your legs, which helps the flow of fluids from your legs back towards the heart.
• Improves circulation in your legs and feet and helps to alleviate pain swelling, & fatigue.
• Nabee's compression socks are the best treatment for varicose or spider veins.
• Nabee Socks ensure that your body's natural recovery systems work optimally while you rest.
Having studied biochemistry and nursing at Georgetown University, I had the ambition to become an anesthetist. However, after three years of working as a nurse, I realized that I was in love with the craft of designing compression socks and entrepreneurship is what lies ahead, not anesthesia. This is when I decided to start Nabee Socks.
Since then, I never looked back. I established my socks company that truly reflects my passion for developing the perfect pair of socks that boosts your lifestyle with effortless style. I cherish my journey as an entrepreneur and have found much joy in my life ever since I put on my first pair of Nabee Socks. My happiness and enthusiasm are evident in all of my services and products. I look forward to creating awesome socks that can bring fun and joy to your life.
Your happiness is all we want. We offer a 100% money back guarantee on your first pair of socks. If you don't like them for any reason, shoot us an e-mail and we will replace them or give you a full refund at no cost.
We recently started shipping all around the world! Please note that based on your location, you may be charged for customs.
All of our socks are made from the highest quality fabric. 72% Nylon and 28% Lycra
Isn't it good?! Nabee means 'butterfly' in Korean and was the name of my father's art gallery. Learn more.
Wear and care instructions can be found here
20 mm Hg at the ankle and 15 mm Hg near the knee. This amount of compression provides all the benefits of graduated compression therapy without causing discomfort.
Do not wear compression socks if you have any of the following conditions: advanced peripheral neuropathy, advanced peripheral obstructive arterial disease, arteriosclerosis, congestive heart failure, extreme deformity of the leg, dermatitis, gangrene, phlebitis, recent skin graft, or vein ligation. Ask your doctor before wearing compression socks if you have any history of blood clots.
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Wow! I just love Nabee socks. Wonderful designs and soft fabric.
The perfect combination of style and comfort. I suggest you try once and you never gonna stop using Nabee again.
Perfect combination of style and comfort. I suggest you try once and you never gonna stop using Nabee again.


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The Great Gambler
The Great Gambler is a 1979 Indian action thriller film, known in Hindi as Sabse Bada Zuari (Hindi: सबसे बड़ा जुआरी), starring Amitabh Bachchan, Zeenat Aman, Neetu Singh and Prem Chopra. It was directed by Shakti Samanta.
|The Great Gambler
Film poster
|Directed by
|Shakti Samanta
|Produced by
|C.V.K. Shastri
|Written by
|C.J. Pavri (adaptation)
Vrajendra Gaur (dialogue)
|Screenplay by
|Shakti Samanta
Ranjan Bose
|Story by
|Vikramaditya (novel)
|Amitabh Bachchan
Zeenat Aman
Neetu Singh
|Music by
|Rahul Dev Burman
|Aloke Dasgupta
|Edited by
|R.P. Bapat
Pran Mehra
Release date
Running time
|163 minutes
Initially, it did poorly at the box office, but it did decent business in Mumbai and has since attained cult status.[1][2] This film is a thriller, and its story is based on international gangsters, spies and secret agents of different countries' intelligence agencies and their undercover operations. This film had high production costs with a significant portions of it being shot in international locations including Cairo, Lisbon, Venice and Rome, and in India many scenes were shot in Goa. The Great Gambler has been widely appreciated for its action, direction and cinematography.
Jai (Amitabh Bachchan) is an expert gambler, has been for as long as he can remember, and has never lost a game. These skills bring him to the attention of the underworld don Ratan Das (Madan Puri), who is interested in hiring him to win large amounts of money from rich people and then influencing them into doing whatever he wants. Jai agrees to do so, and plays successfully, though unknowingly to entrap Nath (Jagdish Raj), who works for the government. After losing large amounts of money, he is blackmailed into revealing the blueprints of a top-secret military laser weapon that can hit any target within 50 miles and is wanted by another underworld don named Saxena (Utpal Dutt). When the Indian police come to know of this, they assign the case to Inspector Vijay (also Amitabh Bachchan), who is a lookalike of Jai.
Jai and Vijay's paths are soon intertwined when both coincidentally sent to Rome where Vijay is sent to retrieve evidence against underworld don Saxena by his former henchman and Jai is onto a money-making scheme where he would marry Mala (Neetu Singh) to inherit her money. Mala however, meets Vijay at the Rome airport and Vijay decides to go along with this to find out who his lookalike is. Jai meanwhile meets Shabnam (Zeenat Aman), a club dancer who mistakes him for Vijay, and was sent by Saxena to stop him on his mission to discover Saxena's plans. It is later revealed that Jai and Vijay are actually long-lost twin brothers and together they team up to stop Saxena from retrieving the laser weapon.
- Amitabh Bachchan as Jay / C.I.D. Inspector Vijay (Double Role)
- Zeenat Aman as Shabnam
- Neetu Singh as Mala
- Roopesh Kumar as Sethi
- Madan Puri as Ratan Das
- Iftekhar as Deepchand
- Utpal Dutt as Mr. Saxena
- Helen as Monica (Dancer)
- Jagdish Raj as Nath
- Prem Chopra as Romesh/Abbasi
- Sujit Kumar as Marconi
- Om Shivpuri as CID Head Mr. Sen Verma (Inspector Vijay's Boss)
- Brahm Bhardwaj as White haired elderly Indian secret agent in Rome.
All lyrics written by Anand Bakshi. Music composed by Rahul Dev Burman.
|"Tum Kitne Din Baad Mile"
|Asha Bhosle
|"O Deewanon Dil Sambhalo"
|Asha Bhosle
|"Raqqasa Mera Naam"
|Mohammed Rafi, Asha Bhosle
|"Do Lafzon Ki Hai Dil Ki Kahaani"
|Asha Bhosle, Sharad Kumar, Amitabh Bachchan
|"Pehle Pehle Pyaar Ki Mulaqaatein"
|Asha Bhosle, Kishore Kumar
1) The song "Do Lafzon Ki Hai Dil Ki Kahaani" was shot on a Gondola in Venice's Grand Canal.
2) The song "Pehle Pehle Pyaar Ki Mulaqaatein" was shot in Eduardo VII Park, Lisbon.
In 1976, Amjad Khan had a severe accident on the Mumbai-Goa highway which left him with broken ribs and a punctured lung. He was going to participate in the shooting of this movie according to the initial casting but did not materialize. Due to this, his role was given to Utpal Dutt.


text:
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This is a free conference to launch an exciting new initiative to support schools in addressing the mental health needs of pupils in primary and secondary schools.
Please click here to download the flyer and the timetable for the day
Published: 04/01/2017
Audience: All Schools
Contact: Mental Health Matters
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So What Is Acid Reflux Really?
Emerging studies in acute reflux esophagitis inside humans support the brand new concept, suggesting that reflux-induced cytokine release may be the future target for healthcare therapies. Sometimes, reflux esophagitis heals with Barrett's metaplasia, a process facilitated by reflux-related nitric oxide (NO) manufacturing and Sonic Hedgehog (Hh) secretion by squamous tissue. We now have shown that SIMPLY NO reduces expression of family genes that promote a squamous cell phenotype, while Hh signaling induces genes that mediate the development of the columnar cell phenotypes of Barrett's metaplasia. Providers targeting esophageal NO creation or Hh signaling certainly could prevent the progress Barrett's esophagus.
This alternative concept is dependent on rat studies, and that is unclear if this particular model of the pathogenesis of reflux esophagitis can be applied to humans. However, a few recent circumstantial evidence within humans suggests that this particular model is valid. Kondo et al. enrolled 14 healthy, male volunteers in addition to randomized those to receive 30 minutes of either saline or acid perfusion by means of a tube with their tip positioned in typically the distal esophagus [8]. Distal esophageal biopsy specimens were obtained before in addition to after the perfusion, and levels of prostaglandin E2 (PGE2), a pro-inflammatory cytokine, were measured. Acid, but not saline perfusion, considerably increased PGE2 levels inside the esophageal mucosa without inducing surface erosions or even immune cell infiltration, indicating that acid exposure leads to cytokine secretion ahead of virtually any effects on epithelial cell viability or immune cellular migration in humans [8].
Body weight, lifestyle, dietary habits and gastroesophageal reflux disease. World J Gastroenterol. Dibley LB, Norton Chemical, Jones R. Non-pharmacological involvement for gastro-oesophageal reflux disease in primary care.
BA-induced apoptosis was suggested to become involved in human malignancies. Cells have the potential and tendency to survive apoptosis.
They found that exposure in the lung to filtered gastric aspirate induced fibrotic changes and severe severe rejection. 55 This type may be useful in elucidating the immunological covariates of which affect the lung's reaction to aspiration. As described under, GORD is prevalent among patients with diverse kinds of ALD. The pathophysiology with this association is not properly characterised.
Consequently, that means there will be a failure rate regarding 10-15 %. Redo antireflux surgery is required in 3-6 % of all patients who else undergo primary antireflux surgical procedure [216–220]. Recurrent reflux symptoms like heartburn plus regurgitation would be the main problems after unsuccessful antireflux surgical procedure and are found in 61 % of patients along with failure [219, 220]. Troublesome dysphagia will be the next most frequent symptom inside failed antireflux surgery (24 %). Combined recurrent poisson and dysphagia is reported in 6 % regarding patients.
Leads to of GERD: Carbohydrate Malabsorption and Bacterial Overgrowth
These people could be native to be able to the esophagus. For illustration, they might be principal cells of the squamous epithelium, or immature tissues that line the system of esophageal submucosal intrigue [16, 17]. The immature progenitor cells may reside in the proximal stomach. Recent studies within mice have suggested of which progenitor cells through the digestive, gastrointestinal cardia, or an unusual population of embryonic-type tissue at the gastroesophageal verse might migrate up the particular esophagus to correct the damaged squamous mucosa [18, 19]. In a rat type of reflux esophagitis, Barrett's metaplasia developed from moving stem cells from the bone fragments marrow that were transported through the blood to be able to the damaged tissue exactly where they differentiated into columnar cells [20].
Infection with the bacteria Helicobacter pylori, which resides inside the stomach and is associated with ulcers of the gastric liner, have been observed in upwards to 40% of GERD cases; though it truly is ambiguous whether H. pylori infection causes GERD (O'Connor 1999; Ferri 2012). Esophageal Cancer – 2 major types of esophageal malignancy are esophageal squamous cell carcinoma and esophageal adenocarcinoma. Esophageal adenocarcinoma EAC arises from metaplasia of tissue within the lower part of the esophagus, and is thought in order to develop as an effect of long-term GERD in addition to Barrett's esophagus (Siersema 2007). Peptic Stricture – healing of ulcerations can lead to the deposit regarding fibrous scar tissue simply because well as a stricture (i. e., narrowing) in the esophagus (Rosemurgy 2011).
Biohack Your own Acid reflux disorder: Treatment Without Harmful Drugs
It represents a premalignant condition of the éloigné esophagus in which squamous epithelial cells are changed by metaplastic intestinal-like columnar epithelium that contains cup cells. Apoptosis seems to maintain esophageal tissue homeostasis, which is regulated by simply p53, and is gradually lost in the metaplasia-dysplasia-carcinoma sequence of Barrett's oesophagus [17]. Similarly, apoptosis is involved in gastric epithelial homeostasis and honesty since its deregulation will be associated with the event of lesions such as atrophic gastritis, peptic ulcers, intestinal metaplasia, and intestinal, digestive, gastrointestinal malignancies [18]. The particular passage of duodenal items through the stomach generates consistent histological changes in the intestinal, digestive, gastrointestinal mucosa (reactive gastropathy) along with antral intestinal metaplasia being one of the nearly all prominent histological characteristics.
Many patients with a hiatal hernia are systematic 10. However, for several patients these symptoms are usually only mild as well as the condition is detected incidentally on a chest radiograph performed for another reason eight, 39. In patients along with sliding hiatal hernias signs are generally attributable to gastroesophageal reflux. Expert opinion suggests that truly asymptomatic paraesophageal hiatal hernias can be found, but are rare.
As I discussed earlier, it has been well established that acid-blocking remedies inhibit the absorption associated with critical minerals and vitamins, such while iron and cobalamin. Acid is needed to split these nutrients from our food for that body in order to absorb. Vitamin B12, in particular, is a key nutritional for your neurological system, plus B12 deficiencies in seniors patients are associated with higher risk of dementia and cognitive declines.