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This concert has already taken place!
Laeiszhalle Hamburg Großer Saal
»Mozart and the Magic Wig«
Children's Concert with the Hamburger Camerata and Andreas Peer Kähler
»Kinder, könnt ihr euch vorstellen, statt vormittags in den Kindergarten oder in die Schule zu gehen und nachmittags Hausaufgaben zu machen, zusammen mit Papa und der großen Schwester in einer ruckelnden Pferdekutsche jahrelang durch ganz Europa zu reisen?« Eine derart ungewöhnliche Kindheit hat man, wenn man – wie Wolfgang Amadeus Mozart vor etwa 250 Jahren – als Wunderkind geboren wird. In einem fröhlichen und abwechslungsreichen Familienkonzert erzählt die Hamburger Camerata mit dem Dirigenten und Moderator Andreas Peer Kähler die ungewöhnliche Lebensgeschichte von Wolfgang Amadeus Mozart – wobei die »magische Perücke« eine große Rolle spielt!
Hamburger Camerata
Andreas Peer Kähler moderation and direction
Promoter: Hamburger Camerata
Concert-Related Events
Food & Drink
Along with a wide range of food options, a large and changing selection of wines and the perfect delicacies to go with them are on offer before events and during the interval.More about Food & Drink
Laeiszhalle Hamburg
Großer Saal
Since 1908, the Laeiszhalle has been a meeting place for Hamburg's musical life. The neo-baroque Laeiszhalle Grand Hall accommodates over 2,000 guests.
Cloakrooms are located in the foyer areas. Baby carriages, wheeled walkers, walking-stick umbrellas, handbags larger than DIN A3 (42 cm x 30 cm) as well as sport bags, backpacks and suitcases must be checked in at the cloakroom. If required, wheeled walkers can be parked in the immediate vicinity of the hall entrances. Our front of house staff is happy to assist you in this regard.
Cloakroom fee: €1.50
The accessible entrance to the Grand Hall and Brahms Foyer is located on Gorch-Fock-Wall. The Brahms Foyer is only accessible to folding wheelchairs or wheelchairs under 75 cm in width.
The accessible entrance to the Recital Hall is located at Dammtorwall 46 (Artists' Entrance). The Recital Hall is only accessible to folding wheelchairs or wheelchairs under 68 cm in width.
Three parking spaces for visitors with disabilities are located at the entrance on Gorch-Fock-Wall. Six parking spaces for visitors with disabilities are available in front of the Artists' Entrance on Dragonerstall.
All halls and spaces are accessible for visitors with disabilities. The Grand Hall has space for six wheelchairs, while the Recital Hall has space for four wheelchairs (audience seats can be dismounted to make space for two further wheelchair spaces). Space for wheelchairs in the Brahms Foyer is available. Further information
Getting Here
Laeiszhalle Hamburg
20355 Hamburg
The Laeiszhalle can be easily reached by bus, underground and bicycle.
The nearest stops include:
Underground line U2: Gänsemarkt / Messehallen
Underground line U1: Stephansplatz
Bus 4, 5, 109, Schnellbus 34, 36: Stephansplatz
Bus 3, 112, Schnellbus 35, 36: Johannes-Brahms-Platz
City bicycle (Stadtrad) station: Sievekingplatz / Gorch-Fock-Wall
Gänsemarkt multistorey car park: Dammtorwall / Welckerstrasse, 20355 Hamburg
First 30 minutes: €2.00
First 60 minutes: €4.00
Rate per further hour or part thereof: €4.00
Night Rate (18:00–06:00): maximum €11.00
24-Hour Rate: maximum €30.00
Photography and Video Recordings
Photography is permitted at the Laeiszhalle for private purposes only. Please respect the privacy of other visitors and help ensure an undisturbed concert experience for all guests and artists. Employees and artists may not be photographed.
Photography, audio or video recordings of concerts and events are strictly prohibited.
Event-related video recordings or photographs for editorial or commercial purposes must be authorised by the Press Office of the Elbphilharmonie and Laeiszhalle.
Smoking Ban
Smoking is prohibited throughout the entire premises of the Laeiszhalle.
All halls and spaces are accessible for visitors with disabilities. More information at www.elbphilharmonie.de/en/accessibility.
Arrival Time
The foyers of the Grand and Recital Halls open their doors 90 minutes before the start of the concert or event. The bars in each foyer open simultaneously.
Admission into the halls begins 30 minutes before the start of the concert or event; for events offering pre-concert talks, admission into the halls begins 60 minutes before the start of the concert.


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In future Genome editing technologies will have therapeutic potential for various incurable diseases i.e. cancer and genetic disorders. The genome editing platforms currently in use have revolutionized the field of genetics. At an accelerating rate these tools are entering areas with direct impact on human beings. We discuss here applications in agriculture, in medicine and Challenges, concerns and ethical implications of CRISPRCas9 and Human genome editing.
The introduction of CRISPR tools takes place in 2012. The power of these technologies allows direct modification of specific DNA sequences at their normal chromosomal locations including changes as small as a single base pair or large deletions, insertions or translocations. It is used to produce models of human disease in experimental organisms and fundamental gene function. [1]
CRISPR-Cas9 is a genome editing tool which is used to target a particular deleterious and disease causing gene in certain genetic disorders. The targeted genes are altered that brings about the changes in the germline to the next generation so that the disease causing genes can be completely eradicated. The impact of genome editing takes place on the security world food supply and therapies. The important uses of it in agricultural and clinical evidences and many social issues were recognized by this technology. [1] It allows the modification of any part in the genome of an organism. The modifications depends upon the DNA repair capabilities of the cells in which the breaks are made [2].
The current world food supply is inadequate and the situation will get worse as populations continue to grow. There are various considerations that are demands on water supplies that is uncertain about changing climates and animal welfare. Genome editing will not provide general solutions to these issues but there are some areas where the technology can help us. [3] It has important Applications to improve plants as well as crops it provide nutrition for the world population. Through genome editing improvements takes place in nutritional values in many species. [4]
In the study related to livestock genome editing applied there so specific applications are still emerging. One example which is currently used is the genetic dehorning of dairy cattle [5]. Because the cattle are kept in close quarters dairy farmers typically remove their horns by physical methods that are painful and expensive. Natural genetic variants that are called polled exist in some beef breeds [6]. This trait could be transferred to dairy herds by traditional breeding but it would be time consuming and so expensive to do so as it would be necessary to perform extensive additional breeding to restore favorable dairy traits. [7]
Genome edited animals and plants are genetically modified organisms GMOs but they differ from the controversial genetically engineered crops currently under cultivation. The latter carry transgenes imported from other species obtained from bacteria. By contrast genome editing allows the precise inactivation of an endogenous gene the conversion of an existing allele to a more favorable one or the precise insertion of an identified variant into additional breeds. The animal and plant products of these modifications are essentially identical to ones that could and in some cases do occur naturally or could be created by traditional breeding methods.
Genome editing like its less efficient predecessors is touted by some for its potential to clear deleterious traits from the family line and criticized by others for its echoes of simplistic and cruel notions of genetic superiority and inferiority. Germline modification causes genetic changes to the embryos changes that are heritable this technique can have unpredictable effects to the future generations. Moreover unethical uses of the technique could emerge from gene editing of the human embryos. [11]
The biology and therapeutic potential of CRISPR-Cas9
In 2013 Feng Zhang opened the window through which genome editing became a therapeutic possibility [12] when he engineered a novel version of CRISPR-Cas9 to edit human genomes [13]. The speed and efficiency of CRISPR-Cas9 is a remarkable leap in research. This feature can enable it to increase the identification of genes that are associated with human diseases and facilitate the development of therapies to correct the mutated gene [14]. Due to its unparalleled genetic specificity scientists are using CRISPR-Cas9 genomic editing technology to facilitate discoveries in cancer biology. Cancer models have been developed using CRISPR-Cas9. [12].
Challenges, concerns and ethical implications of CRISPRCas9 Human genome Editing
Genome editing in human embryos using CRISPR-Cas9 could have unpredictable effects to the future generations. CRISPR-Cas9 technology could be used for non therapeutic modifications. This procedure will open the door to the loss of human diversity and eugenics [15]. The nuclease may not be as efficient. The nuclease may not necessarily cleave both copies of the target gene or the cells may start dividing before the corrections are completed resulting in genetic mosaic. Mosaicism is frequently masked. Mosaicism causes major phenotypic changes and reveal expression of lethal genetic mutations [16]. Some of the genetic disorders results from mosaicism include Down syndrome, Klinefelter syndrome and Turner syndrome.
While CRISPR-Cas9 genome editing technology holds promise to personalized medicine, human genetic modification and the development of new drugs, the technology has raised caution flags. Genome editing technology is a cautionary tale. We can easily get caught up in the glamour of scientific and technological advancement while at the same time oblivious to the ethical ramification of such scientific and technological advancement.
Some scientists have expressed concern that human germline editing has not only crossed the ethical redline. The recent research by Chinese scientists using it to edit the embryo genome was not completely successful but had to be abandoned at its preliminary stage. These off target mutations can be deleterious as they can cause cell death and transformation. Embryo germline editing could be exploited in nontherapeutic research. For example it can be used to produce designer babies by eliminating undesired qualities and replaced them with desired ones.
Genome editing technology should not hinder the promising area of therapeutic development are involved in making genetic changes in somatic cells. Due to it challenges and ethical concerns raised by genome editing technology a temporary moratorium should be called on the technology to allow scientific community and to engage in a broad discussion to map the way forward for this technology.
Despite the plethora of other applications much of discussion about this gene has focused on its potential for editing the nuclear DNA of human gametes are called germline editing. The critiques largely break down into two large categories that are used in ethical analyses of many different kinds of technologies and human actions.
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Zelensky appoints Oleksandr Syrsky as commander of Ukrainian Ground Forces
President of Ukraine Volodymyr Zelensky appointed Oleksandr Syrsky as commander of the Ground Forces of the Armed Forces of Ukraine.
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By another decree, the president dismissed Oleksandr Syrsky from the post of commander of the Joint Forces, and appointed Volodymyr Kravchenko to this post.
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Last weekend was the Karneval Der Kulturen in Berlin.
It was by far the hottest day of the year, way too hot to be spending it outside actually. But no one cared, because when it's Karneval der Kulturen in Berlin, there is no other place to be than at the march on Sunday. I wanted to start my day of looking at some of the wagons pass by Südstern with Tissi and Gina, then meet up with my friends but I bumped into my babe Mehtap and a few streets down Carina instead, saw Aminata from Germany's Next Topmodel and lost Nisi in the crowd of the YAM wagon, when it all went to fast. I only had my iPhone camera with me because it was either two bottles of iced water or my DSLR camera in my bag and surviving KDK seemed more important than HQ pictures. I gotta admit though that my iPhone diary has a more personal touch to it. Turns out it wasn't such a bad thing I wasn't out without my camera.