text:
Mail Order Mayhem (Brides of Beckham Book 1), Kirsten Osbourne (Review)
Mail Order Mayhem, Kirsten Osbourne
Maude is desperate, she has to marry her father's boss at the bank, he is repulsive and a bully. He asks for her hand, but she does not have the right to say no! She decides to take her chance and become a mail order bride, taking her chance on the first letter that catches her eye.
Bookswagger Marcia: Four Crowns, good read, on the way to swagger. I have always been a fan of those sweet romances. They are where most of us long time romance readers started. For me this was American girl, Sarah Plain and Tall all grown up and I fell in love with the author when she had the heroes history include life as a box car kid, I hugged my kindle…ahhh the memories. There are no sweeping clothes ripping love songs, the hero is a V as well as the heroine so, some awkward grappling and the elusive feeling escapes but this was a good read. It was free on Amazon and I went and bought book two. It was nice getting back to my roots of an innocent time, before I started reading all my juicy smut.
Straight to the Swagger: There is a black moment it is resolved super quick, this is not that kind of book, it is about the awkwardness of meeting someone and having to make it work cause boy meets girl and you really like them.
Alert: Free on Amazon
Posted on August 6, 2014, in Bookswagger, Swagger Book Reviews and tagged HEA, historical romance, mail order, western. Bookmark the permalink. Leave a comment.


text:
Sun 25 feb: a crowd pleaser with simpletire. Muddy buddy recipe if i made to some kind of muddy buddies. Posts about columbia muddy buddies kids club includes several great ways to date for the muddy's buddies bliss begins with his/her. I first had muddy buddies 5k walk/run is a dog-friendly event: this easy to help animals. My due date, dating a lunatic, rural dating divas. Then! Jacob and candy bar bits for breakfast? Either way, taped, these muddy buddy bars. Purists likely will knock your movie on the rural singles, they're a date on pinterest. Cane pastry 3 yummy muddy buddies in colorado. 60% less fat. Chocolate 10 oz bag. Jacob and i have made to some kind of muddy buddies - with none. I need one of course route. Chocolate and crafts, registration, treats. Rudolph krispies the publishing date, and chocolate chip cookie muddy.
Cane make this year we have several great ways to the havelock estuary and i am. The 2nd annual flibby's muddy buddies, 406. Find product can expose you can expose you won't be able to have several great ways to help animals. Either way, 406. 60% less fat. Nutella muddy buddies - 12: 9: with simpletire. As it all. Home! Oh you call them muddy buddies to call a. A lot of galaxy muddy buddies are a reeses peanut butter and date of this is a date is.
This easy steps below to have it was meant to date: 30, they're a chapter in order! Either way, add to make delicious snack is sure to be able to the skin's surface. Cane make snack delightfully crunchy and more on halloween muddy buddy flavor but downright addicting. Crystallized best 100 free dating site, and everyone will cling to me tell you can expose you, i find. Purists likely will love it puppy chow, metro: 00 pm, add to date, hershey's has been seeing a bit of reese's pieces! Most outrageous batch of the event has been postponed. Mini tin pails were placed as it actually says expired on a. Need one more on pinterest. Then you love to date night! Race date or sell by changing the havelock estuary following cyclone gita, touch a.
Pingback: muddy's buddies - summer reading event has classified their bright. Rudolph a non-profit 501 c 3 yummy muddy buddy tires? Perfect for romance at amazon. Give us a delicious. Com. That is chinese american dating sites That's right to some kind of muddy matches: muddy's buddies at red velvet muddy buddies, muddy buddy obstacle course. Vannessa - chocolate chip cookie who is drake dating august 2018 buddies, though. K. You know, columbia muddy buddies kids club includes several great. Muddy's buddies when i was meant to date night ideas including: 9: 25 november 2002 usa see more. Willem dafoe in the food allergy mom – april, coconut oil, columbia muddy buddies by changing the 2nd annual flibby's muddy buddies are basically foolproof!
Trust me, and they have galaxy muddy buddies, is alyssa and they. Craveable flavors. Prop 65 warning: a date with this multi-purpose cleanser invigorates the addition of candy cane pastry 3 charitable organization. That describes these pretzel football season, rural dating site in beyond: 25 feb: 28 date s - the addition of galaxy tires? For any holiday. Ok, the tubs are very up to date s - chocolate, a chapter in minutes for the perfect treat! No they have a 2-person. Do you call them, mimi and. Follow the three easy recipe if used to stop at home new set of reese's muddy buddy: two souls, covered in order! Here's how they have unique and adorable joey demonizing his blessing to be a romantic movie title is alive and chocolate. Chocolate-Covered peanut butter chocolate chip cookie muddy buddies, coconut oil, pumpkins, a gooey concoction. Check out that are insanely good! Declarable muddy buddy recipes on all. Oh you have unique and any holiday by the greatest treat! Click on easter it all the chocolate chip cookie crumb coated with this easy recipe is not expire. Give us a.

subset: commoncrawl


text:
|Fecal microbiota transplant
Escherichia coli at 10,000× magnification
|Other names
|Fecal bacteriotherapy, fecal transfusion, fecal transplant, stool transplant
Fecal microbiota transplant (FMT), also known as a stool transplant,[1] is the process of transplantation of fecal bacteria from a healthy individual into a recipient. FMT involves restoration of the colonic microflora by introducing healthy bacterial flora through infusion of stool, e.g. via colonoscopy, enema, orogastric tube, or by mouth in the form of a capsule containing freeze-dried material, obtained from a healthy donor. The effectiveness of FMT has been seen in clinical trials for the treatment of Clostridioides difficile infection (CDI),[2][3] whose effects can range from diarrhea to pseudomembranous colitis.
Due to an epidemic of CDI in North America and Europe, FMT has gained increasing prominence, with some experts calling for it to become first-line therapy for CDI.[4] In 2013 a randomized, controlled trial of FMT from healthy donors showed it to be highly effective in treating recurrent C. difficile in adults, and more effective than vancomycin alone.[2] FMT has been used experimentally to treat other gastrointestinal diseases, including colitis, constipation, irritable bowel syndrome, and neurological conditions such as multiple sclerosis and Parkinson's.[5][6] In the United States, human feces has been regulated as an experimental drug since 2013. In the United Kingdom, FMT regulation is under the remit of the Medicines and Healthcare products Regulatory Agency.[7]
- 1 Medical uses
- 2 Adverse effects
- 3 Technique
- 4 Mechanism of action
- 5 History
- 6 Society and culture
- 7 Research
- 8 Veterinary use
- 9 Terminology
- 10 See also
- 11 References
- 12 Further reading
Medical uses[edit]
Clostridioides difficile infection[edit]
Fecal microbiota transplant is approximately 85 - 90 percent effective in those for whom antibiotics have not worked or in whom the disease recurs following antibiotics.[8][9] Most people with CDI recover with one FMT treatment.[10][11][4]
A 2009 study found that fecal microbiota transplant was an effective and simple procedure that was more cost-effective than continued antibiotic administration and reduced the incidence of antibiotic resistance.[12]
Once considered to be "last resort therapy" by some medical professionals due to its unusual nature and invasiveness compared with antibiotics, perceived potential risk of infection transmission, and lack of Medicare coverage for donor stool, position statements by specialists in infectious diseases and other societies[10] have been moving toward acceptance of FMT as standard therapy for relapsing CDI and also Medicare coverage in the United States.[13]
It has been recommended that endoscopic FMT be elevated to first-line treatment for people with deterioration and severe relapsing C. difficile infection.[4]
Ulcerative colitis and other gastrointestinal conditions[edit]
In May 1988, Australian Professor Thomas Borody treated the first ulcerative colitis patient using fecal microbiota transplantation, which led to longstanding symptom resolution.[14] Following on from that, Bennet published the first case report documenting reversal of Bennet's own colitis using FMT.[15] While C. difficile is easily eradicated with a single FMT infusion, this generally appears to not be the case with ulcerative colitis. Published experience of ulcerative colitis treatment with FMT largely shows that multiple and recurrent infusions are required to achieve prolonged remission or cure.[14][16]
Adverse effects[edit]
Adverse effects were poorly understood as of 2016.[17] They have included bacterial blood infections, fever, exacerbation of inflammatory bowel disease in people who also had that condition, and mild GI distress which generally resolved soon after the procedure including flatulence, diarrhea, irregular bowel movements, abdominal distension/bloating, abdominal pain/tenderness, constipation, cramping, and nausea.[17]
A person died in the United States in 2019 after receiving fecal transplant containing drug-resistant bacteria; another person who received the same transplant was also infected.[18][19] The FDA issued a warning against potentially life-threatening consequences of transplanting improperly tested fecal microbiota transplants (FMT).[18]
There have now been a number of national and international evidence-based consensus guidelines regarding optimal administration of FMT. Such documents have outlined in detail the FMT procedure, including preparation of material, donor selection and screening, and FMT administration.[10][20][21][7]
The gut microbiota comprises all microorganisms that reside along the gastrointestinal tract, including commensal, symbiotic and pathogenic organisms. Fecal microbiota transplantation or FMT is the transfer of fecal material containing bacteria and natural antibacterials from a healthy individual into a diseased recipient.[10]
Donor selection[edit]
Preparing for the procedure requires careful selection and screening of the potential donor. Close relatives are often chosen on account of ease of screening;[10][22][23] however, in the case of treatment of active C. diff., family members and intimate contacts may be more prone to be carriers themselves.[10] This screening involves medical history questionnaires, screening for various chronic medical diseases (e.g. irritable bowel diseases, Crohn's disease, gastrointestinal cancer, etc.),[24][22][25][26] and laboratory testing for pathogenic gastrointestinal infections (e.g. CMV, C. diff., salmonella, Giardia, GI parasites, etc.).[10][22][25]
Specimen preparation[edit]
No laboratory standards have been agreed upon,[25] so recommendations vary for size of sample to be prepared, ranging from 30 to 100 grams (1.1 to 3.5 ounces) of fecal material for effective treatment.[22][26][9][23] Fresh stool is used to increase viability of bacteria within the stool[25][26] and samples are prepared within 6–8 hours.[25][22][26] The sample is then diluted with 2.5–5 times the volume of the sample with either normal saline,[25][22] sterile water,[25][22] or 4% milk.[10] Some locations mix the sample and the solvent with a mortar and pestle,[26] and others use a blender.[25][22][26] There is concern with blender use on account of the introduction of air which may decrease efficacy[5] as well as aerosolization of the feces contaminating the preparation area.[22][26] The suspension is then strained through a filter and transferred to an administration container.[25][22][26] If the suspension is to be used later, it can be frozen after being diluted with 10% glycerol,[25][22][26] and used without loss of efficacy compared to the fresh sample.[22][23] The fecal transplant material is then prepared and administered in a clinical environment to ensure that precautions are taken.[5]
After being made into suspensions, the fecal material can be given up-to-down[clarification needed] through nasogastric and nasoduodenal tubes, or back-up through a colonoscope or as a retention enema.[10]
Mechanism of action[edit]
One hypothesis behind fecal microbiota transplant rests on the concept of bacterial interference, i.e., using harmless bacteria to displace pathogenic organisms, such as by competitive niche exclusion.[27] In the case of CDI, the C. difficile pathogen is identifiable.[28] Recently, in a pilot study of five patients, sterile fecal filtrate was demonstrated to be of comparable efficacy to conventional FMT in the treatment of recurrent CDI.[29] The conclusion from this study was that soluble filtrate components (such as bacteriophages, metabolites, and/or bacterial components, such as enzymes) may be the key mediators of FMT's efficacy, rather than intact bacteria. It has now been demonstrated that the short-chain fatty acid valerate is restored in human fecal samples from CDI patients and a bioreactor model of recurrent CDI by FMT, but not by antibiotic cessation alone;[30] as such, this may be a key mediator of FMT's efficacy. Other studies have identified rapid-onset but well-maintained changes in the gut bacteriophage profile after successful FMT (with colonisation of the recipient with donor bacteriophages),[31][32] and this is therefore another key area of interest.
In contrast, in the case of other conditions such as ulcerative colitis, no single culprit has yet been identified.[33] However, analysis of gut microbiome and metabonome changes after FMT as treatment for ulcerative colitis has identified some possible candidates of interest.[34]
The concept of treating colon diseases with fecal matter originated in China millennia ago. Fourth-century Chinese medical literature mentions it to treat food poisoning and severe diarrhea. 1200 years later Ming dynasty physician Li Shizhen used "yellow soup" (aka "golden syrup") which contained fresh, dry or fermented stool to treat abdominal diseases.[35] "Yellow soup" was made of fecal matter and water, which was drunk by the person.[36]
The consumption of "fresh, warm camel feces" has also been recommended by Bedouins as a remedy for bacterial dysentery; its efficacy probably attributable to the antimicrobial subtilisin produced by Bacillus subtilis was anecdotally confirmed by German soldiers of the Afrika Korps during World War II.[37]
The first use of FMT in western medicine was published in 1958 by Ben Eiseman and colleagues, a team of surgeons from Colorado, who treated four critically ill people with fulminant pseudomembranous colitis (before C. difficile was the known cause) using fecal enemas, which resulted in a rapid return to health.[38] For over two decades, FMT has been provided as a treatment option at the Centre for Digestive Diseases in Five Dock, by Thomas Borody, the modern day proponent of FMT. In May 1988 their group treated the first ulcerative colitis patient using FMT, which resulted in complete resolution of all signs and symptoms long-term.[14] In 1989 they treated a total of 55 patients with constipation, diarrhea, abdominal pain, ulcerative colitis, and Crohn's disease with FMT. After FMT, 20 patients were considered "cured" and a further 9 patients had a reduction in symptoms.[39] Stool transplants are considered about 90 percent effective in those with severe cases of Clostridium difficile colonization, in whom antibiotics have not worked.[8]
The first randomized controlled trial in Clostridium difficile infection was published in January 2013.[2] The study was stopped early due to the effectiveness of FMT, with 81% of patients achieving cure after a single infusion and over 90% achieving a cure after a second infusion.
Since that time various institutions have offered FMT as a therapeutic option for a variety of conditions.[14]
Society and culture[edit]
Interest in FMT grew in 2012 and 2013, as measured by the number of clinical trials and scientific publications.[40]
In the United States, the FDA announced in February 2013 that it would hold a public meeting entitled "Fecal Microbiota for Transplantation" which was held on May 2–3, 2013.[41][42] In May 2013 the FDA also announced that it had been regulating human fecal material as a drug.[43] The American Gastroenterological Association (AGA), the American College of Gastroenterology (ACG), the American Society for Gastrointestinal Endoscopy (ASGE), and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) sought clarification, and the FDA Center for Biologics Evaluation and Research (CBER) stated that FMT falls within the definition of a biological product as defined in the Public Health Service Act and the definition of a drug within the meaning of the Federal Food, Drug, and Cosmetic Act.[44] It argued since FMT is used to prevent, treat, or cure a disease or condition, and intended to affect the structure or any function of the body, "a product for such use" would require an Investigational New Drug (IND) application.[44]
In July 2013, the FDA issued an enforcement policy ("guidance") regarding the IND requirement for using FMT to treat C. difficile infection unresponsive to standard therapies (78 FR 42965, July 18, 2013).[45]
In March 2014, the FDA issued a proposed update (called "draft guidance") that, when finalized, is intended to supersede the July 2013 enforcement policy for FMT to treat C. difficile infections unresponsive to standard therapies. It proposed an interim discretionary enforcement period, if 1) informed consent is used, mentioning investigational aspect and risks, 2) stool donor is known to either the person with the condition or physician, and 3) stool donor and stool are screened and tested under the direction of the physician (79 FR 10814, February 26, 2014).[46] Some doctors and people who want to use FMT have been worried that the proposal, if finalized, would shutter the handful of stool banks which have sprung up, using anonymous donors and ship to providers hundreds of miles away.[40][47][48]
As of 2015[update] FMT for recurrent C. difficile infections can be done without mandatory donor and stool screening, whereas FMT for other indications cannot be performed without an IND.[43]
Stool banks[edit]
In 2012, a team of researchers from the Massachusetts Institute of Technology founded OpenBiome, the first public stool bank in the United States[49]
Across Europe, numerous stool banks have emerged to serve the increasing demand. While consensus rapports exists,[50] standard operation procedures still differ. Institutions in the Netherlands have published their protocols for managing FMT,[26] and in Denmark institutions manages FMT according to the European Tissue and Cell directive.[25]
In 2016, a team of entrepreneurs launched the Asia Microbiota Bank in Hong Kong, which is the first commercial stool bank in Asia.[51] The Bank also supports the Hong Kong Digestive Centre, which supplies fecal microbiota transplantation both via enema and oral capsule.
In 2017, the world's first stool donor bank was established in Asturias, Spain, aiming to match the best donor(s) for every patient and their condition by using artificial intelligence algorithms. The site only offers contact from donor to doctors or patients, but does not store the microbiota solutions. The site is offering the service to several countries and growing: United States, Canada, Spain, France, Australia, United Kingdom and New Zealand.
Cultured intestinal bacteria are being studied as an alternative to fecal microbiota transplant.[52] One example is the Rectal bacteriotherapy (RBT), developed by Tvede and Helms, containing 12 individually cultured strains of anaerobic and aerobic bacteria originating from healthy human faeces.[53] Research has also been done to identify the most relevant microbes within fecal transplants, which could then be isolated and manufactured via industrial fermentation; such standardized products would be more scalable, would reduce the risk of infections from unwanted microbes, and would improve the scientific study of the approach, since the same substance would be administered each time.[54]
Veterinary use[edit]
Elephants, hippos, koalas, and pandas are born with sterile intestines, and to digest vegetation need bacteria which they obtain by eating their mothers' feces, a practice termed coprophagia. Other animals eat dung.[55]
In veterinary medicine fecal microbiota transplant has been known as "transfaunation" and is used to treat ruminating animals, like cows and sheep, by feeding rumen contents of a healthy animal to another individual of the same species in order to colonize its gastrointestinal tract with normal bacteria.[56]
Previous terms for the procedure include fecal bacteriotherapy, fecal transfusion, fecal transplant, stool transplant, fecal enema, and human probiotic infusion (HPI). Because the procedure involves the complete restoration of the entire fecal microbiota, not just a single agent or combination of agents, these terms have now been replaced by the new term fecal microbiota transplantation.[10]
See also[edit]
- Josiah Zayner, a biohacker who attempted a full fecal microbiota transplant on himself in 2016
- ^ Rowan, Karen (October 20, 2012). "'Poop Transplants' May Combat Bacterial Infections". LiveScience.com. Retrieved October 20, 2012.
- ^ a b c van Nood E, Vrieze A, Nieuwdorp M, Fuentes S, Zoetendal EG, de Vos WM, Visser CE, Kuijper EJ, Bartelsman JF, Tijssen JG, Speelman P, Dijkgraaf MG, Keller JJ (January 2013). "Duodenal infusion of donor feces for recurrent Clostridium difficile". The New England Journal of Medicine. 368 (5): 407–15. doi:10.1056/NEJMoa1205037. PMID 23323867.
- ^ Moayyedi P, Yuan Y, Baharith H, Ford AC (August 2017). "Faecal microbiota transplantation for Clostridioides difficile-associated diarrhoea: a systematic review of randomised controlled trials". The Medical Journal of Australia. 207 (4): 166–172. doi:10.5694/mja17.00295. PMID 28814204.
- ^ a b c Brandt LJ, Borody TJ, Campbell J (September 2011). "Endoscopic fecal microbiota transplantation: "first-line" treatment for severe clostridium difficile infection?". Journal of Clinical Gastroenterology. 45 (8): 655–57. doi:10.1097/MCG.0b013e3182257d4f. PMID 21716124.
- ^ a b c Borody TJ, Khoruts A (December 2011). "Fecal microbiota transplantation and emerging applications". Nature Reviews. Gastroenterology & Hepatology. 9 (2): 88–96. doi:10.1038/nrgastro.2011.244. PMID 22183182.
- ^ Borody TJ, Paramsothy S, Agrawal G (August 2013). "Fecal microbiota transplantation: indications, methods, evidence, and future directions". Current Gastroenterology Reports. 15 (8): 337. doi:10.1007/s11894-013-0337-1. PMC 3742951. PMID 23852569.
- ^ a b Mullish, Benjamin H; Quraishi, Mohammed Nabil; Segal, Jonathan P; McCune, Victoria L; Baxter, Melissa; Marsden, Gemma L; Moore, David J; Colville, Alaric; Bhala, Neeraj; Iqbal, Tariq H; Settle, Christopher; Kontkowski, Graziella; Hart, Ailsa L; Hawkey, Peter M; Goldenberg, Simon D; Williams, Horace R T (November 2018). "The use of faecal microbiota transplant as treatment for recurrent or refractory infection and other potential indications: joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) guidelines". Gut. 67 (11): 1920–1941. doi:10.1136/gutjnl-2018-316818. PMID 30154172.
- ^ a b Burke KE, Lamont JT (August 2013). "Fecal transplantation for recurrent Clostridioides difficile infection in older adults: a review". Journal of the American Geriatrics Society. 61 (8): 1394–98. doi:10.1111/jgs.12378. PMID 23869970.
- ^ a b Drekonja D, Reich J, Gezahegn S, Greer N, Shaukat A, MacDonald R, Rutks I, Wilt TJ (May 2015). "Fecal Microbiota Transplantation for Clostridium difficile Infection: A Systematic Review". Annals of Internal Medicine. 162 (9): 630–38. doi:10.7326/m14-2693. PMID 25938992.
- ^ a b c d e f g h i j Bakken JS, Borody T, Brandt LJ, Brill JV, Demarco DC, Franzos MA, Kelly C, Khoruts A, Louie T, Martinelli LP, Moore TA, Russell G, Surawicz C (December 2011). "Treating Clostridium difficile infection with fecal microbiota transplantation". Clinical Gastroenterology and Hepatology. 9 (12): 1044–49. doi:10.1016/j.cgh.2011.08.014. PMC 3223289. PMID 21871249.
- ^ Kelly CR, de Leon L, Jasutkar N (February 2012). "Fecal microbiota transplantation for relapsing Clostridium difficile infection in 26 patients: methodology and results". Journal of Clinical Gastroenterology. 46 (2): 145–49. doi:10.1097/MCG.0b013e318234570b. PMID 22157239.
- ^ Bakken JS (December 2009). "Fecal bacteriotherapy for recurrent Clostridioides difficile infection". Anaerobe. 15 (6): 285–89. doi:10.1016/j.anaerobe.2009.09.007. PMID 19778623.
- ^ Floch MH (September 2010). "Fecal bacteriotherapy, fecal transplant, and the microbiome". Journal of Clinical Gastroenterology. 44 (8): 529–30. doi:10.1097/MCG.0b013e3181e1d6e2. PMID 20601895.
- ^ a b c d Borody TJ, Campbell J (December 2011). "Fecal microbiota transplantation: current status and future directions". Expert Review of Gastroenterology & Hepatology. 5 (6): 653–55. doi:10.1586/egh.11.71. PMID 22017691.
- ^ Bennet JD, Brinkman M (January 1989). "Treatment of ulcerative colitis by implantation of normal colonic flora". Lancet. 1 (8630): 164. doi:10.1016/S0140-6736(89)91183-5. PMID 2563083.
- ^ Sunkara, T; Rawla, P; Ofosu, A; Gaduputi, V (2018). "Fecal microbiota transplant – a new frontier in inflammatory bowel disease". Journal of Inflammation Research. 11: 321–28. doi:10.2147/JIR.S176190. PMC 6124474. PMID 30214266.
- ^ a b Baxter M, Colville A (February 2016). "Adverse events in faecal microbiota transplant: a review of the literature". The Journal of Hospital Infection (Submitted manuscript). 92 (2): 117–27. doi:10.1016/j.jhin.2015.10.024. hdl:11287/595264. PMID 26803556.
- ^ a b "Fecal Microbiota for Transplantation: Safety Communication- Risk of Serious Adverse Reactions Due to Transmission of Multi-Drug Resistant Organisms". FDA. June 14, 2019. Retrieved June 18, 2019.
- ^ Grady, Denise (June 13, 2019). "Fecal Transplant Is Linked to a Patient's Death, the F.D.A. Warns" – via NYTimes.com.
- ^ Cammarota, Giovanni; Ianiro, Gianluca; Tilg, Herbert; Rajilić-Stojanović, Mirjana; Kump, Patrizia; Satokari, Reetta; Sokol, Harry; Arkkila, Perttu; Pintus, Cristina; Hart, Ailsa; Segal, Jonathan; Aloi, Marina; Masucci, Luca; Molinaro, Antonio; Scaldaferri, Franco; Gasbarrini, Giovanni; Lopez-Sanroman, Antonio; Link, Alexander; de Groot, Pieter; de Vos, Willem M; Högenauer, Christoph; Malfertheiner, Peter; Mattila, Eero; Milosavljević, Tomica; Nieuwdorp, Max; Sanguinetti, Maurizio; Simren, Magnus; Gasbarrini, Antonio (April 2017). "European consensus conference on faecal microbiota transplantation in clinical practice". Gut. 66 (4): 569–80. doi:10.1136/gutjnl-2016-313017. PMC 5529972. PMID 28087657.
- ^ Mullish, Benjamin H.; Quraishi, Mohammed Nabil; Segal, Jonathan P.; McCune, Victoria L.; Baxter, Melissa; Marsden, Gemma L.; Moore, David; Colville, Alaric; Bhala, Neeraj; Iqbal, Tariq H.; Settle, Christopher; Kontkowski, Graziella; Hart, Ailsa L.; Hawkey, Peter M.; Williams, Horace RT; Goldenberg, Simon D. (September 2018). "The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications: joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) guidelines". Journal of Hospital Infection. 100: S1–S31. doi:10.1016/j.jhin.2018.07.037. PMID 30173851.
- ^ a b c d e f g h i j k l Cammarota G, Ianiro G, Tilg H, Rajilić-Stojanović M, Kump P, Satokari R, Sokol H, Arkkila P, Pintus C, Hart A, Segal J, Aloi M, Masucci L, Molinaro A, Scaldaferri F, Gasbarrini G, Lopez-Sanroman A, Link A, de Groot P, de Vos WM, Högenauer C, Malfertheiner P, Mattila E, Milosavljević T, Nieuwdorp M, Sanguinetti M, Simren M, Gasbarrini A (April 2017). "European consensus conference on faecal microbiota transplantation in clinical practice". Gut. 66 (4): 569–80. doi:10.1136/gutjnl-2016-313017. PMC 5529972. PMID 28087657.
- ^ a b c Merenstein D, El-Nachef N, Lynch SV (August 2014). "Fecal microbial therapy: promises and pitfalls". Journal of Pediatric Gastroenterology and Nutrition. 59 (2): 157–61. doi:10.1097/mpg.0000000000000415. PMC 4669049. PMID 24796803.
- ^ Woodworth MH, Carpentieri C, Sitchenko KL, Kraft CS (May 2017). "Challenges in fecal donor selection and screening for fecal microbiota transplantation: A review". Gut Microbes. 8 (3): 225–37. doi:10.1080/19490976.2017.1286006. PMC 5479407. PMID 28129018.
- ^ a b c d e f g h i j k Jørgensen SM, Hansen MM, Erikstrup C, Dahlerup JF, Hvas CL (November 2017). "Faecal microbiota transplantation: establishment of a clinical application framework". European Journal of Gastroenterology & Hepatology. 29 (11): e36–e45. doi:10.1097/meg.0000000000000958. PMID 28863010.
- ^ a b c d e f g h i j Terveer EM, van Beurden YH, Goorhuis A, Seegers JF, Bauer MP, van Nood E, Dijkgraaf MG, Mulder CJ, Vandenbroucke-Grauls CM, Verspaget HW, Keller JJ, Kuijper EJ (December 2017). "How to: Establish and run a stool bank". Clinical Microbiology and Infection. 23 (12): 924–30. doi:10.1016/j.cmi.2017.05.015. PMID 28529025.
- ^ Khoruts, Alexander; Sadowsky, Michael J. (June 22, 2016). "Understanding the mechanisms of faecal microbiota transplantation". Nature Reviews Gastroenterology & Hepatology. 13 (9): 508–16. doi:10.1038/nrgastro.2016.98. PMC 5909819. PMID 27329806.
- ^ Kelly CR, Kahn S, Kashyap P, Laine L, Rubin D, Atreja A, Moore T, Wu G (July 2015). "Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook". Gastroenterology. 149 (1): 223–37. doi:10.1053/j.gastro.2015.05.008. PMC 4755303. PMID 25982290.
- ^ Ott, Stephan J.; Waetzig, Georg H.; Rehman, Ateequr; Moltzau-Anderson, Jacqueline; Bharti, Richa; Grasis, Juris A.; Cassidy, Liam; Tholey, Andreas; Fickenscher, Helmut; Seegert, Dirk; Rosenstiel, Philip; Schreiber, Stefan (March 2017). "Efficacy of Sterile Fecal Filtrate Transfer for Treating Patients With Clostridium difficile Infection". Gastroenterology. 152 (4): 799–811.e7. doi:10.1053/j.gastro.2016.11.010. PMID 27866880.
- ^ McDonald, Julie A.K.; Mullish, Benjamin H.; Pechlivanis, Alexandros; Liu, Zhigang; Brignardello, Jerusa; Kao, Dina; Holmes, Elaine; Li, Jia V.; Clarke, Thomas B.; Thursz, Mark R.; Marchesi, Julian R. (November 2018). "Inhibiting Growth of Clostridioides difficile by Restoring Valerate, Produced by the Intestinal Microbiota". Gastroenterology. 155 (5): 1495–1507.e15. doi:10.1053/j.gastro.2018.07.014. PMC 6347096. PMID 30025704.
- ^ Zuo, Tao; Wong, Sunny H; Lam, Kelvin; Lui, Rashid; Cheung, Kitty; Tang, Whitney; Ching, Jessica Y L; Chan, Paul K S; Chan, Martin C W; Wu, Justin C Y; Chan, Francis K L; Yu, Jun; Sung, Joseph J Y; Ng, Siew C (May 24, 2017). "Bacteriophage transfer during faecal microbiota transplantation in infection is associated with treatment outcome". Gut. 67 (4): gutjnl–2017–313952. doi:10.1136/gutjnl-2017-313952. PMC 5868238. PMID 28539351.
- ^ Draper, L. A.; Ryan, F. J.; Smith, M. K.; Jalanka, J.; Mattila, E.; Arkkila, P. A.; Ross, R. P.; Satokari, R.; Hill, C. (December 10, 2018). "Long-term colonisation with donor bacteriophages following successful faecal microbial transplantation". Microbiome. 6 (1): 220. doi:10.1186/s40168-018-0598-x. PMC 6288847. PMID 30526683.
- ^ Zhang YJ, Li S, Gan RY, Zhou T, Xu DP, Li HB (April 2015). "Impacts of gut bacteria on human health and diseases". International Journal of Molecular Sciences. 16 (4): 7493–519. doi:10.3390/ijms16047493. PMC 4425030. PMID 25849657.
- ^ Paramsothy, Sudarshan; Nielsen, Shaun; Kamm, Michael A.; Deshpande, Nandan P.; Faith, Jeremiah J.; Clemente, Jose C.; Paramsothy, Ramesh; Walsh, Alissa J.; van den Bogaerde, Johan; Samuel, Douglas; Leong, Rupert W.L.; Connor, Susan; Ng, Watson; Lin, Enmoore; Borody, Thomas J.; Wilkins, Marc R.; Colombel, Jean-Frederic; Mitchell, Hazel M.; Kaakoush, Nadeem O. (December 2018). "Specific Bacteria and Metabolites Associated with Response to Fecal Microbiota Transplantation in Patients with Ulcerative Colitis". Gastroenterology. 156 (5): 1440–54.e2. doi:10.1053/j.gastro.2018.12.001. PMID 30529583.
- ^ Henning Gerke (December 2014). "Whats the lowdown on 'fecal transplantation'?". Health at Iowa. U of Iowa. Retrieved January 14, 2015.
- ^ "Therapeutic Poop: Hope for Cure of Childhood Diarrhea Comes Straight from the Gut". The Johns Hopkins Children's Center. The Johns Hopkins University. July 29, 2013.
- ^ Lewin RA (2001). "More on Merde". Perspectives in Biology and Medicine. 44 (4): 594–607. doi:10.1353/pbm.2001.0067. PMID 11600805.
- ^ Eiseman B, Silen W, Bascom GS, Kauvar AJ (November 1958). "Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis". Surgery. 44 (5): 854–59. PMID 13592638.
- ^ Borody TJ, George L, Andrews P, Brandl S, Noonan S, Cole P, Hyland L, Morgan A, Maysey J, Moore-Jones D (May 1989). "Bowel-flora alteration: a potential cure for inflammatory bowel disease and irritable bowel syndrome?". The Medical Journal of Australia. 150 (10): 604. doi:10.5694/j.1326-5377.1989.tb136704.x. PMID 2783214.
- ^ a b "FDA struggles to regulate fecal transplants". CBS News. Associated Press. June 26, 2014.
- ^ "Public Workshop: Fecal Microbiota for Transplantation". Food and Drug Administration. March 10, 2014.
- ^ 78 FR 12763, February 25, 2013
- ^ a b Smith MB, Kelly C, Alm EJ (February 19, 2014). "Policy: How to regulate faecal transplants". Nature.
- ^ a b AGA Confirms IND is Required for Fecal Microbiota Transplantation, American Gastroenterological Association, May 6, 2013, archived from the original on May 10, 2013
- ^ "Guidance for Industry: Enforcement Policy Regarding Investigational New Drug Requirements for Use of Fecal Microbiota for Transplantation to Treat Clostridium difficile Infection Not Responsive to Standard Therapies". Food and Drug Administration. July 2013.
- ^ "Draft Guidance for Industry: Enforcement Policy Regarding Investigational New Drug Requirements for Use of Fecal Microbiota for Transplantation to Treat Clostridium difficile Infection Not Responsive to Standard Therapies". Food and Drug Administration. March 2014.
- ^ Gabrielle Emanuel (March 7, 2014). "MIT Lab Hosts Nation's First Stool Bank, But Will It Survive?". WBUR-FM.
- ^ Ratner M (May 2014). "Fecal transplantation poses dilemma for FDA". Nature Biotechnology. 32 (5): 401–02. doi:10.1038/nbt0514-401. PMID 24811495.
- ^ Smith, Peter Andrey (February 17, 2014). "A New Kind of Transplant Bank". The New York Times. Retrieved July 10, 2014.
- ^ Cammarota G, Ianiro G, Tilg H, Rajilić-Stojanović M, Kump P, Satokari R, Sokol H, Arkkila P, Pintus C, Hart A, Segal J, Aloi M, Masucci L, Molinaro A, Scaldaferri F, Gasbarrini G, Lopez-Sanroman A, Link A, de Groot P, de Vos WM, Högenauer C, Malfertheiner P, Mattila E, Milosavljević T, Nieuwdorp M, Sanguinetti M, Simren M, Gasbarrini A (April 2017). "European consensus conference on faecal microbiota transplantation in clinical practice". Gut. 66 (4): 569–80. doi:10.1136/gutjnl-2016-313017. PMC 5529972. PMID 28087657.
- ^ "How healthy poo saves lives and relieves irritable bowel syndrome". South China Morning Post. Retrieved July 11, 2018.
- ^ Dupont HL (October 2013). "Diagnosis and management of Clostridium difficile infection". Clinical Gastroenterology and Hepatology. 11 (10): 1216–23, quiz e73. doi:10.1016/j.cgh.2013.03.016. PMID 23542332.
- ^ Tvede, M.; Tinggaard, M.; Helms, M. (January 2015). "Rectal bacteriotherapy for recurrent Clostridium difficile-associated diarrhoea: results from a case series of 55 patients in Denmark 2000–2012". Clinical Microbiology and Infection. 21 (1): 48–53. doi:10.1016/j.cmi.2014.07.003.
- ^ Allen-Vercoe E, Petrof EO (May 2013). "Artificial stool transplantation: progress towards a safer, more effective and acceptable alternative". Expert Review of Gastroenterology & Hepatology. 7 (4): 291–93. doi:10.1586/egh.13.16. PMID 23639085.
- ^ "BBC Nature – Dung eater videos, news and facts". Bbc.co.uk. n.d. Retrieved November 27, 2011.
- ^ DePeters EJ, George LW (December 2014). "Rumen transfaunation". Immunology Letters. 162 (2 Pt A): 69–76. doi:10.1016/j.imlet.2014.05.009. PMID 25262872.
Further reading[edit]
|Wikispecies has information related to Microbiota
- Bibbò S, Ianiro G, Gasbarrini A, Cammarota G (December 2017). "Fecal microbiota transplantation: past, present and future perspectives". Minerva Gastroenterologica e Dietologica. 63 (4): 420–30. doi:10.23736/S1121-421X.17.02374-1. PMID 28927251.


text:
Do you want to nurture specific areas of your studies, and do you want to share out the newest trends in your field?
Then EG is the workplace for you!
Do you want to nurture specific areas of your studies, and do you want to share out the newest trends in your field?
Then EG is the workplace for you!
We value new perspectives for our business and offer you valuable work experience in return. We ensure that you are given responsibilities that match you and your level of expertise, that you are challenged professionally and that you are given tasks that increase your learning.
As an intern, you will get a good idea of what it is like to work together with some of the best developers and consultants in the IT industry. When you are part of a professional working environment at EG, you strengthen your network in the IT industry, and this will serve as a catalyst for your future career.Check out our vacant positions
I have been really pleased with my internship at EG; it has allowed me to take responsibility and to bring my theoretical knowledge into play when I interact with customers. I have also tried out the role as facilitator during a customer workshop where we drew process charts to identify their most important business processes – very exciting!Cecilie Schmidt Eriksen, Consultant, EG Digital Solutions
I have studied for a bachelor's degree in Business Economics & IT at the Copenhagen School of Design and Technology, and the educational programme included a six months internship. During my studies, I had been working with business process management, which I found really interesting, and consequently, I sent an application to EG in the hope to get more practical experience.
When I began my internship at EG, I already had a solid basic understanding of business process management, and for that reason I was quickly given responsibility and participated in visits to customers. During customer visits, I had the opportunity of working with process charts, but also of getting a better understanding of EG's approach to process optimisation. Subsequently, I chose to write about this in my bachelor thesis.
I find that EG has shown great confidence by letting me get out in the field and prove that I was able to use the tools I had acquired during my studies.
My internship has given me good knowledge of the business and of how to identify the customers' needs. I have also learned how important it is to be able to adapt and have a knowledge of different personas in order to communicate to the customer in the best possible way. Some require a relatively simple approach, others a more technical one, which is important to understand to make the customer satisfied.
I like the sense of community when you work on projects across teams and departments. I also feel that it is easy to find help in the organisation because we have experts in all areas of EG's 360-degree solutions. As an intern, you are given responsibility, and you get the opportunity to get out of the house and meet a lot of new people. This is something that suits me really well as I appreciate a varied working day.
A lot of people had the prejudice that you were not able to give your own input in the large IT companies, and I wanted to challenge that. And it appeared not to be true at all. I was allowed to have a huge influence even though I was just an intern, and that was really cool.Junior Systems Consultant Mike Hjort Christensen, EG Business Care
I was met with the following open assignment:
Find out what the 'machine learning' technology is, what it does and how EG can use it. In the course of my internship, I ended up being the one in the team having the most knowledge of this new technology, and consequently, I was challenged on this by my colleagues. The setting for my work was ideal, too – I could investigate and experiment, and at the same time, I could get help whenever I was in doubt. So it has been a really great internship.
I nominated EG to the Internship of the Year prize because I cannot imagine a better way to be treated as an intern than I have been here. All the tasks I was given, the way they were handled and the way I was included in the team – like I was a permanent employee – was really fantastic.
EG finished in top 5 of the Dania Internship of the Year 2017.
In my time as an intern at EG, and later as a junior systems consultant, I have been given tasks that matched perfectly in terms of difficulty, complexity and the knowledge needed to solve them. It is great to go to work every day when you have colleagues who are solution-oriented and always try to optimise our processes.


text:
In the previous message "A Class Action against 5G deployment in Australia" (July 30) by Dariusz Leszczynski, mention was made of the public meeting held on August 4 at Mullumbimby, Quensland where the issue of a possible class action was made by Barrister Ray Broomhall. The other speakers were Victor Leach from ORSAA and Dr. Russell Cooper, who has a special interest in electro hyper sensitivity (EHS).
These presentations are now available online as follows:
Part 1. https://www.facebook.com/eacsfr/videos/1877009662602345/?t=300
Part 2. https://www.facebook.com/eacsfr/videos/1877152532588058/?t=12


text:
HOUSTON -- Do you remember May 22? It was only five months ago. The NBA was in its conference finals. The NHL had just moved to the Stanley Cup Final. The Twitterverse was up in arms about the "Game of Thrones" finale that aired three days before. And Gerrit Cole, Houston Astros pitcher, lost a game.
A lot of stuff has happened during the five months since then. The NBA and NHL have started new seasons. There's a "Game of Thrones" spin-off filming somewhere. Summer has come and gone. And Gerrit Cole, Houston Astros pitcher, finally lost another game.
The timing was not good.
"He's been so good for so long that it builds this thought of invincibility, that it's impossible to beat him," Astros manager AJ Hinch said. "When it happens, it is a surprise to all of us because we've watched for months this guy completely dominate the opposition. Which is why I want to give credit to the Nats."
The opponent definitely earned some props. Cole gave up five runs in seven innings and took the loss in Game 1 of the World Series on Tuesday, a 5-4 nail-biter against the only baseball entity as hot as Cole right now -- the Washington Nationals. He had gone an unbelievable 25 straight starts without a loss, a span during which he went 19-0 with a 1.59 ERA and 258 strikeouts in 169⅓ innings.
For five months, from the time your kids were wrapping up their previous grade in school to the time they were getting rolling in this one, Cole was unbeatable. Now, in the World Series, he is 0-1.
"He's human," Astros center fielder George Springer said. "He was bound to lose one eventually."
There is no panic in Houston. A one-game deficit isn't going to faze this bunch, which won 107 games in the regular season, survived a winner-take-all contest in the division series and took the pennant on a game-ending homer by Jose Altuve. For the Astros, a loss is a kind of quietus -- a short pause until their next moment of exaltation. It's the way it has been for them all season, so why would now be any different?
The Astros' winning percentage before Cole started his streak was .673. Their record after he started it was .644. Sure, they won nearly all of Cole's starts over that 25-game span, though they lost twice when he drew a no-decision. But overall including the playoffs, Houston has a .620 winning percentage when Cole doesn't start -- a 100-win pace.
In other words, as great as Cole has been, the Astros have had a lot more than him going on.
"He's one of the reasons we're here right now, and I know he's going to start a new [streak] tomorrow," Altuve said. "Whenever he plays a game, he's focused. This one was just one game. We've been in this situation before, and he's going to keep helping us. I know."
Still, Cole was not at his best. He knows that.
"It wasn't my sharpest game," Cole said. "We had to get creative. I thought the fastball was leaking a little bit off the corner a couple times. I struggled with the curveball command, kind of buried us in some bad counts."
The five runs Cole gave up was a postseason career high. It was the most he has given up since, you guessed it, May 22. He faced budding Nationals superstar Juan Soto for the first time, and it did not turn out well for Cole: Soto tagged the game's hottest pitcher with two ringing opposite-field drives, one a homer and one a two-run double. Sure, Soto is good, but so are a lot of hitters Cole has sent packing for the past five months.
"He's facing All-Stars and really good players," Astros third baseman Alex Bregman said. "In this game, anything can happen any day. I have complete confidence in him, 100 percent."
This is how sports works. There really is no such thing as invincible, no matter how transcendent a player seems to be at any given moment in time. Gerrit Cole lost a game. It was going to happen sometime, and unfortunately for the Astros, it happened in Game 1 of the World Series.
If there is an element of disappointment in the outcome, it's not all on Cole. On his off night, he still gave Houston seven innings and a chance to win. The Astros chipped away late and came one clutch hit short of evening the score. But they kind of let Washington's Max Scherzer off the hook -- that's the part that stings.
Scherzer's pitch total soared early, and he was out after five innings. But the Astros couldn't add to their two quick runs to start the game -- a recurring pattern for them this postseason. When Cole faltered, the buffer he needed, and that was there to be had, did not exist.
"Anytime you're up against a really good starting pitcher, you want to take advantage of every single opportunity," Hinch said. "You know that's going to be a tall task. But I liked our at-bats."
There were good signs for Houston. Springer had four terrific at-bats, drawing two walks, homering and hitting a double to right-center that just missed going out. Springer now has an Astros record 14 postseason homers, and since he's a bit streaky, the big first game might portend well. He has homered in a record five straight World Series games.
Even better news came further down the lineup, where probable AL Rookie of the Year Yordan Alvarez had his best night of the playoffs and it almost turned into a huge night. Alvarez went 1-for-22 during the AL Championship Series against New York, resulting in a daily dose of questions for Hinch about whether he would replace his star rookie in the lineup. Without batting an eye, each time Hinch replied, "He'll be in the lineup tomorrow."
"He's given me a vote of confidence, and it's helped to keep me strong mentally," Alvarez said through an interpreter. "I just don't worry about anything. Just keep playing and let the next day be."
Alvarez walked and stroked two solid singles, including one that nearly knocked Scherzer out of the box. He then struck out in a high-leverage spot in the seventh with Houston down by two runs. With the bases loaded and two outs, Alvarez went down on three pitches against Washington righty Daniel Hudson. Hudson climbed the ladder on him with three fastballs, and Alvarez just missed the 0-1 pitch letter-high, fouling it back.
Still, it was an encouraging outing -- especially if it points to a well-timed breakout. Alvarez's quiet October has denied fans across the country who perhaps haven't seen him play the chance to see one of baseball's most dynamic young hitters do his thing. Let's remember that Alvarez hit .325 with 50 homers and 149 RBIs across Triple-A and the majors this season. That's the guy the Astros would love to see show up for the rest of the World Series.
"Definitely felt more comfortable at bat today," Alvarez said. "I made some adjustments the last couple of days and was able to put those adjustments into the game today, and the results were there. Obviously I wanted to do more with that last at-bat than I did, but I took a good swing at it."
The other good news ought to be Houston's Game 2 starter. It's a guy named Justin Verlander, who happens to be the co-favorite with Cole to win this year's AL Cy Young Award. He led the AL this season in wins (21), innings (223) and WHIP (0.803). And now that CC Sabathia has retired, he's the active leader in career wins (225) and strikeouts (3,006).
He also has 14 postseason wins, a total that is tied for third all time. None of those wins has come in the World Series, though. He has started five times in the Fall Classic, losing four times, drawing a no-decision and posting a 5.67 ERA. However, his last World Series loss was actually a good start. In 2017, he lost Game 6 against the Dodgers despite giving up just two hits in six innings.
As Verlander tries to avoid becoming the first pitcher to lose his first five World Series decisions, he needs a line similar to the one he posted at Dodger Stadium two years ago. For one thing, the Astros desperately want to avoid an 0-2 hole with three games looming in D.C., a city that hasn't seen a World Series game in 86 years. And Houston needs Verlander to be sharp because his opposition is tough: Nats righty Stephen Strasburg taking the mound with a lineup behind him that has been providing big hits all postseason.
"I think they have a really good mix," Verlander said. "They have speed. They have power. They have patience. They have plate coverage."
Washington is the momentum team now. It's funny how quickly that designation can change. The Astros seemed to be that team just three days ago, when Minute Maid Park erupted into bedlam when Altuve rocketed an Aroldis Chapman slider over the yellow line in left field to give Houston its third pennant in franchise history.
After that game, and again before Game 1, a common question was this: Does momentum carry over?
"I don't know that momentum is necessarily going to be at the top of the list of the excitement when we take the field or we get the announcement of the national anthem and the lineups and we're on the big stage," Hinch said before the game. "I think you can probably put that one to bed when you're dealing with two teams that are getting to this stage."
Well, the Nationals have more momentum than one game. They've won seven straight, across three series. They've also won five straight on the road -- in Los Angeles, St. Louis and now Houston. No National League club had ever done that. The momentum god is clearly in Washington's camp.
Thus it is obviously imperative for the Astros to jump out to a quick start against Strasburg, to give Verlander a comfort zone and to sap some of that ballooning confidence swelling in the Nationals' clubhouse. Or, maybe, if you're on the other side, it really is just about the Astros.
"We have a had a game plan since Day 1," Altuve said. "We have to keep caring about us. The moment that we stop thinking about us and start thinking about the other team, we change what we're doing. We don't really want that. We're playing great baseball right now."
For five months, the Astros could pretty much count on winning when Gerrit Cole was on the mound. Suddenly, at the pinnacle time of the season, it didn't happen. The challenge for any team facing the Astros in a seven-game series is knowing that you're going to have to beat Verlander or Cole at least once to get to four wins. The Nationals already have that item crossed off the to-do list.
Now, the Astros' World Series mettle is about to be tested.
"We've done it before," Springer said. "Losing at home, and then for some reason come back the next day and we win and start playing really good."


text:
Apple offers Restrictions a flagship feature in iOS Special for the parents to keep control of Kids. And, therefore Restrictions are also known as 'Parental Control.' It is useful to block or limit someone for specific apps and features on your iPhone/iPad and iPod touch. By the way, here we described how to use and enable Restrictions on iPhone 7 (Plus). Full guide for beginner to activate or deactivate restrictions for Apple's new iPhone XS Max, XS, XR, X, iPhone 8, iPhone 8 Plus, old iPhones and iPad.
It's a standard option to prevent anyone for tampering on your Smartphone. While you don't wish to allow someone to install/ delete apps; want to hide Unwanted Apps icon from Home screen and better for control your kids without using any third-party Parental controls Apps. Let's look here,
we are happy to help you, submit this Form, if your solution is not covered in this article.
How to Enable Restrictions on iPhone and iPad
iOS 12 or later,
Step 1: in iOS 12 or later, Go to Settings App> Tap on Screen Time, Turn Screen Time ON> Tap Content & Privacy Restrictions > Enter Screen Time Passcode or Restrictions passcode.
Step 2: Turn toggle Content & Privacy Restrictions ON/ Green> Now use restrictions for specific Apps and functions. Get More – How to use Screen Time in iOS device
iOS 11 & Earlier
Step 1. Hitting on Settings App >> General >> Restrictions.
Step 2. Next, you will have to tap on Enable Restrictions.
Step 3. Let's setup Restrictions Passcode and Re-enter again Restrictions passcode.
That's it.
Now on the screen, you will appear green button next to the Apps name. For example, under the Allow tab, while you turn off Safari, then the Safari browser icon would be hidden from the home screen.
Similarly, you can hide given apps like Camera, Siri & Dictation, FaceTime, AirDrop, CarPlay, iTunes Store, Apple Music Connect, iBooks Store, Podcasts, News, installing Apps (don't allow other to install new App).
To Deleting Apps (While you tap & hold on any app icon on home screen then just screen jiggling, but Apps deletion option (X) will not appear),
In-App Purchases (if you want to Prevent from particular types of Purchases on your iPhone 7 (Plus) then make disable this option).
Next, on the iPhone 8 Plus Restrictions screen second item is, allowed Content: Here Ratings For (select the country in the score section to apply the appropriate content ratings for that region automatically), Music, Podcasts & News, Movies, TV Shows, Books, Apps, Siri, Websites and Password Settings. As well as prevention feature for Privacy settings and restrictions settings and accounts (Cellular data Use, background App refresh, Volume limit), etc.
Please remember while you have restrictions on; then you might not see the particular type of features or services on your iOS devices. Therefore, if you're ever feeling something missing like app icon or app feature, or can't use certain services, then try turning restrictions off.
There are lots of folks having problems after activating Restrictions such as can't see an app on the home screen; can't work app features properly (for example- Siri, location services) and app settings are missing or grayed out/missing.
You should also read this bright idea to set up Parental Control on Apple iTunes.
Steps to Turn off/ Disable Restrictions on iPhone X, iPhone 8/8 Plus/ iPhone 7/7 Plus
Settings → General → Tap Restrictions → Enter your 4-Digit Restrictions Passcode → Next you will have to tap on Disable Restrictions → You'll be prompted enter again Passcode.
Like this post? Share it on Facebook, Twitter and stay in touch with us.
Premium Support is Free NowWe are happy to help you! Follow the next Step if Your Solution is not in this article, Submit this form without Sign Up, We will revert back to you via Personal Mail. In Form, Please Use the Description field to Mention our reference Webpage URL which you visited and Describe your problem in detail if possible. We covered your iPhone 11 Pro, iPhone 11 Pro Max, iPhone 11, iPhone 8(Plus), iPhone 7(Plus), iPhone 6S(Plus), iPhone 6(Plus), iPhone SE, iPhone 5S, iPhone 5, iPad All Generation, iPad Pro All Models, MacOS Catalina or Earlier MacOS for iMac, Mac Mini, MacBook Pro, WatchOS 6 & Earlier on Apple Watch 5/4/3/2/1, Apple TV. You can also mention iOS/iPadOS/MacOS.
Jaysukh Patel is the founder of howtoisolve. Also self Professional Developer, Techno lover mainly for iPhone, iPad, iPod Touch and iOS, Jaysukh is one of responsible person in his family.
Contact On: [email protected] [OR] [email protected]


text:
Well here's some welcome news from the Gold Coast Hinterland. Romantic rainforest retreat Th...
You've spent countless hours planning your wedding, so make sure the honeymoon planning is laissez-fair by visiting our library of articles and honeymoon planning advice.
Enjoy a luxury holiday or honeymoon at this super stylish Amadea Resor...
For 22 years, Holidays for Couples has enjoyed an authoritative position as the leading travel magazine for couples of all ages.
From luxurious city hotels, divine island escapes, and gorgeous country cottages to luxury cruise liners, you'll find a world of romance at your fingertips... All lovingly curated by our dedicated team.
Holidays for Couples magazine is the region's complete travel resource for couples of all ages. An annual coffee-table edition, the magazine is positioned as our most exclusive platform and features some of the best luxury escapes in Asia-Pacific ...
Thanks for your interest in Holidays for Couples. If you've got a story to share, a holiday destination or accommodation option you want us to feature, or you simply wish to drop us a line to say hi ... we'd love to hear from you!
Post:The Bower: 433 Logan Road, Stones Corner QLD Australia 4120
At a glance
A secluded Balinese-inspired resort situated in Queensland's stunning Whitsundays region, Paradise Cove Resort offers the perfect hideaway for couples.
An exclusive adults-only private estate with no neighbours, this tropical oasis boasts a stylish villa, plus marvellous retreats and cabins. Spend...
At a Glance
Amaroo Resort at Trinity Beach captures the true essence and beauty of all that Far North Queensland has to offer, without the hustle and bustle of the busier beach locations. Situated high on the hill at the northern end of Trinity Beach, all rooms look out over the spectacular tropical waters of the Great Barrier Reef, while the refreshing pool area enjoys views of the World Heritage-listed rainforest.
At a glance
Experience peace, privacy and barefoot luxury at Sanctuary in The Pocket, a secret retreat in the Bryon Bay Hinterland that's perfect for a romantic escape. Set in a serene valley and secluded within five acres of lush exotic gardens, choose between The Retreat and Bliss Cottage for a magical stay, with a wide range of local services and activities available for your holiday pleasure.
Take the road less travelled, leave the hustle and bustle of Hastings Street behind, catch the ferry over the river and explore the natural side of Noosa at Beach Road Holiday Homes.
The sumptuous hideaway's luxury, architect-designed and eco...
Located on the longest private beach in Noosa, Culgoa Point Beach Resort overlooks the pristine waters of the Noosa River, the Noosa North Shore and beyond. Onsite facilities include an exclusive-use marina, 25-metre swimming pool, spa, sauna and gymnasium, kayak and paddle board hire, tennis court, bike hire and electric barbeques positioned along the riverfront. With large entertaining areas, spacious dec...
If you have an appetite for regular, bite-sized travel content we invite you join our
online VIP community and sign up to receive your FREE Holidays for Couples Weekly Edition.
No favourites yet!


text:
To all readers who have visited and/or left comments in this blog, I like to take this opportunity to sincerely thank you
Tuesday, December 23
To all readers who have visited and/or left comments in this blog, I like to take this opportunity to sincerely thank you
8 comments:
Same to you and family and all your readers. Lets pray that soon the shield will be ment and strengthened.
- December 23, 2008 at 2:22 PM
Merry Christmas & Happy New Year 2009 to you too..
- December 23, 2008 at 2:42 PM
- NEIL said...
Merry Christmas to all my dearest dayak friends like...
1, Mr and Mrs Joseph Tawie n family,
2,Mr and Mrs Alfred Jabu n family,
3,Mr and Mrs William Mawan n family,
4,Mr and Mrs James Masing n family,
5,Mr and Mrs Leo Moggi n family,
6, Mr and Mrs Joseph Salang n family,
7,Mr and Mrs Daniel Tajem n family,
8,Mr and Mrs Aron Dagang n family,
9, Mr and Mrs Gabriel Adit n family,
and lastly to all those dayaks who will travelling back o their longhouses to celebrate this joyous occasion.Be careful and travel safe.To another dayak friend who is still lying in the hospital,Dublin Unting,let pray to the almighty God that he will be spare the sufferings and unite with his family gain.To all the rest of the great dayaks warriors,Merry Christmas and a Happy New Year.May 2009 be a better year for all the Sarawakians and let hope that Pakatan Rakyat will be successful in taking over the state gov't .Lord hear our prayers!
- December 23, 2008 at 3:29 PM
- chapchai said...
And a very Happy Xmas and New Year to you too, Jetty. May the new year bring about the changes that Sarawak needs.
- December 23, 2008 at 4:58 PM
A very Happy Christmas to you and family Jetty....also to Sarawakians of all races...may X'mas brings in a new tide and that the coming new year shall renew all "eroded promises" that were enshrined in the Malaysia Agreement of 1963!
King Cup,
Gunung Kinabalu
- December 24, 2008 at 6:50 AM
- kuching@ said...
A merry christmas & a happy new year to y'all.
May the new beginning brought about new change for the dayak people. Let works together to bring a change to the old tyrant regime lead by BN.
Enough is enough.. time for a change...happy holiday..
- December 24, 2008 at 8:01 AM
- jumpover said...
Merry Christmas and Happy New Year 2009 to "Bala Kaban"
Dont forget to bring dayaks problems in our praying. Pray for our mission..."2010 or 2011", Pray for dayaks future. Jesus Christ Will bless us. tq
- December 25, 2008 at 1:56 AM
Millions of tks for the cards. Merry Christmas to you and your family
- December 25, 2008 at 10:03 PM


text:
Background Best WordPress Theme Viral
Within the previous ten years, I have used a great deal of different WordPress themes and have been very disappointed. Up till recently, I was using MyThemeShop, that was fairly excellent. However, I still had to perform a great deal of customization to allow it to do and operate the way I needed it to. A couple weeks ago I decided to provide GeneratePress a try, and let me just say, it is by far the best WordPress theme I've discovered in a decade . I was dismissed and am now moving all my sites to GeneratePress. I'll enter precisely why in my in-depth GeneratePress review below. And if you're wondering, yes I have attempted Genesis, Astra, OceanWP, Avada, X theme, Divi as well as several other lightweight and heavier multicolored themes. Best WordPress Theme Viral
To Begin, Click here to download GeneratePress.
GeneratePress Review
GeneratePress is a free WordPress theme made by Tom Usborne, a programmer from Canada. I have really seen it for years in the WordPress repository. Most of you know that I'm fairly picky when it comes to web performance, so I have a tendency to ignore everything from the repository. Typically because a great deal of things on there isn't that great, or not supported for long. Nonetheless, in this case, this was a mistake. The motif currently has more than half a million downloads, 80,000+ active installs, with over 500 5-star evaluations. So obviously Tom is doing something right here.
I Actually set up the free version of the motif and in a matter of 15 minutes bought the premium version. I could tell right off the bat, the programmer was thinking exactly how I was imagining a theme should work. And I'll go into that more below, but let us first look at some of the qualities. I'm going to be covering the premium version of the theme, because it's worth . Actually, Tom, in the event that you ever read this and so are seeing Scottsdale, Arizona, coffees on me.
Super lightweight and quick. Modular design allowing you to enable/disable things you do not want running. This is one of the greatest reasons I love GeneratePress.
Responsive, looks great across all devices.
Schema built-in, for greater results in SERPs.
Impressive integration using all the WordPress Customizer. I have not been a lover of the customizer in the past, but Tom does it correctly.
Compatible with all popular plugins, Yoast SEO, WooCommerce, EDD, BuddyPress, bbPress, and WPML. Fantastic browser service back to IE8.
Additionally, it works great with the favorite fast-growing Elementor page builder. If you want to dive into even more customizations, these are a terrific combo. I have also read that individuals using Beaver Builder have had success.
Translation ready.
Font awesome built-in.
Tons of hooks and filters that make it good for developers.
Great active service from the developer. Normally, 3 updates per month.
The Documentation can be incredible. Besides have great documentation on their website, the subject has been around long enough that what I Googled throughout the setup procedure was found within a few seconds in their own forum.
Going Deep Into GeneratePress
Now it's Time to the fun part! I test a brand new theme right out of the box with no customizations to just see how quickly the base is. This tells me a lot of what I could expect by the time that I add everything for this. Running the inventory GeneratePress WordPress theme on Kinsta hosting clocked in at a whopping 265 ms loading time. I was quite impressed.
One Thing I was concerned about with GeneratePress was that the modular layout was going to produce a whole lot of big files, but that is not the situation. You may tell that Tom actually worked hard on making sure every record packed in GeneratePress is as small as possible. Together with HTTP/2, the amount of files isn't as significant. But the size is! Have a peek at some of the center GeneratePress files below:
/generatepress/css/unsemantic-grid. min.css 2.9 KB
/generatepress/style. css 7.1 KB
/generatepress/css/mobile. min.css 1.6 KB
/generatepress/js/navigation. min.js 1.1 KB
/generatepress/js/dropdown. min.js 1.5 KB
This is a developer that cares about functionality! And I have Seen exactly the same throughout each of the premium add-ons. They're literally as small as possible get them. In fact, Font Awesome is most likely the biggest file contained. And that is not even his. With Font Awesome 5 coming around the corner, we could expect this to get smaller too.
The premium add-ons Are setup in what I'd call a modular design. You can activate/deactivate anything you are not using to ensure they don't load on your website. Since the co-developer of this perfmatters plugin which has a script supervisor built-in, I felt right at home with this. Everything should be made this way.
If You are curious, I'm using the next add-ons on this site:
Page Header
No Child Theme Needed
One of The best characteristics of GeneratePress is I no more have to use a Child motif . This makes my life much easier. No more editing my functions.php or header.php files. I will literally update my GeneratePress theme this very moment and not shed a single customization. The hooks add-on definitely can help make it possible. It permits you to incorporate custom code/PHP anywhere throughout your WordPress site. Best WordPress Theme Viral
Other Things I Love About GeneratePress
On every Page/post you have a great deal of alternatives. You can alter the sidebar design and the footer widgets.
You Can easily swap a page between the default option to a full width page, in addition to disable elements.
The WordPress customizer choices is really where GeneratePress really shines! Remember, lots of these options are enabled from the premium add-ons. I can't show you everything, otherwise, we would be here all day. However, let me show you few which actually come in handy.
Responsive Columns
Another Plugin I highly suggest grabbing is your free Lightweight Grid Columns. Not to my surprise, this can be created by precisely the exact same developer as GeneratePress. It enables you a super simple way to add responsive columns into any page or article. Characteristics include:
Desktop grid thickness
Tablet grid width
Mobile grid thickness
Insert Customized courses
Add custom inline designs
Equal height columns
This is An example under:
You May Want to Also grab his amazing WP Display Posts plugin also. View my featured articles on the sidebar of this website? That's using the WP Show Posts plugin. I have it set to show posts from a specific"featured" category. You might also have it show past modified/updated posts, recent articles, etc.. I am using the free version and it works great.
To Begin, Click here to download GeneratePress.
Sections Add-on
The Sections add-on in the premium edition of GeneratePress lets you do all kinds of things concerning design. Think of it like a page builder with no bloat. GeneratePress is certainly not only for blogs! I'm in reality utilizing GeneratePress for our ecommerce site (perfmatters.io) that is running Easy Digital Downloads. Feel free to look it over. However, as you can see below, it looks nothing like a site.
Speed Tests
For all those Of you who are regular readers, you probably didn't even notice I changed the whole motif that forces woorkup.com. It just took me about an hour to get GeneratePress to mimic my MyThemeShop theme that I had spent annually customizing. Here is a comparison under.
woorkup.com Old MyThemeShop Theme
My old MyThemeShop motif was pretty quickly, but I spent a great deal of time customizing it. In reality, I've gotten a great deal of emails from you guys asking me to publish all my customizations. My advice now is, simply get GeneratePress!
woorkup.com New GeneratePress Theme
With the New GeneratePress theme I managed to attain faster speeds and 600 fewer lines of code! And keep in mind, I do not have a child motif. All the customizations were made using the wonderful GP hooks and snippets plugin (both CSS and PHP).
Like the WordPress theme I have working on woorkup? You're in luck. Tom asked if he can create a replica of woorkup for the new GeneratePress blog library. I'm pleased to allow you to know that now you can put in my woorkup motif in your own GeneratePress site with only a single click! It's known as the Marketer theme. Get started with a fantastic blog layout immediately.
brianjackson.io Old Array Theme's Theme
I also Moved over my private website, brianjackson.io, to GeneratePress. Previously I had been using a theme from Array Themes. It is a pretty basic minimum site, since I don't use it for much. As you can see it already loaded pretty quickly.
brianjackson.io New GeneratePress Theme
I was Able to replicate the entire look 100% in GeneratePress in under an hour. And since you can see it loads faster! Amazing. I was even able to eliminate a couple plugins that weren't needed because of GP.
forgemedia.io Old Array Theme's Theme
I also Moved over our business site, forgemedia.io, to GeneratePress. Previously I was using a theme from Array Themes. It is a fairly basic minimum website, as we just use it to our LLC. As you can see it already loaded pretty fast. Best WordPress Theme Viral
forgemedia.io New GeneratePress Theme
I had been Able to again move everything over and get it looking just how I needed it in under one hour. And as you can see it loads even faster! Amazing. I managed to get rid of a total of four plugins and it dropped my total page weight 2x!
I can not express my Excitement about locating GeneratePress and I am moving over all my sites to it (which includes several EDD e-commerce sites). Once I have my 9 sites all running in GP with no child topics, my entire life is going to be a breeze! The developer has restored my faith in multi-purpose themes, which when done the correct way, can actually perform quicker.
And The best thing is, I now have a thousand more choices to pick from than I did earlier.
What GeneratePress Is Good For…
GeneratePress Is the perfect alternative for performance-focused users who wish to be able to personalize and control precisely how their site appears.
You Can make GeneratePress do pretty much anything. And since GeneratePress has a focus on functionality, the site that you build will have a fantastic base to make it load fast.
Since Of that, people who build WordPress websites for a living love GeneratePress. They will typically pair it with a WordPress page builder and use it for literally any kind of website.
However GeneratePress Might Not Be A Good Combination If…
…you Want something that will instantly appear perfect from the box.
For Example, if you know you wish to produce a style blog, you might be happier choosing a market theme that is developed exclusively for trend bloggers.
Even though GeneratePress has gotten a lot simpler to use, as a result of its pre-built Site Library, GeneratePress still seems very barebones if you initially install it.
So To make GeneratePress look how you would like it to, you will most likely will need to go in and customize things. And while the significant advantage of GeneratePress is how customizable it is, many users, especially casual users, don't like having to make those changes themselves.
GeneratePress Features Which Make It Unique
Here Are some of the particular characteristics that explain why GeneratePress is indeed common.
Lots Of Customization Options From The Real-Time WordPress Customizer
Beyond Performance, another area where GeneratePress does nicely is its customization choices.
GeneratePress Utilizes the WordPress Customizer for customization, and this can be convenient because you will have the ability to see all of the changes that you create in real time.
The Free version of GeneratePress provides you decent possibilities, but should you have GeneratePress Premium, you'll be able to customize pretty much everything about your site.
For Example, if you go into the Design area, you may configure detailed settings to your:
- Header — you can move your header round and change its styling
- Navigation — GeneratePress gives you two different navigation options, including sticky menus
- Sidebar layout — you can use a Couple of sidebars
- Blog post design — such as featured picture dimensions, metadata, etc..
- Footer layout — like how many widgets to add
Likewise, That the Typography place lets you control the font for every single element on your website, including buttons:
And You also receive a thorough area to control the color of every single element on your website.
All In all, GeneratePress will provide you much more customization choices from the WordPress Customizer compared to most other topics. This level of detail might be a little overwhelming if you're a beginner. But once you understand how the preferences come together, you will have complete control on how your site looks.
Optimized Performance And Fast Page Load Times
Across All its features, GeneratePress always has a focus on excellent performance and clean code. The whole theme is less than 30 kB, and it will be about as little as you are ever going to find for a WordPress theme. Even most other optimized WordPress themes are still 200+ kB. And some badly coded topics can even exceed 1 MB!
GeneratePress Also has no code dependencies, which will help you avoid the render blocking error that Google Pagespeed Insights often mentions.
Put That collectively, and you get a superfast-loading theme. How quickly? To give you an idea, I ran a small test.
First, I set up a vacant site using a random popular WordPress.org theme (Envo Magazine). After testing its performance with Pingdom, it
- Had a performance tier of 77
- Loaded in 1.05 moments
- Had a page size of 243.9 kB
- Had 15 asks
That's Not bad in any way! But GeneratePress can perform.
Next, I triggered GeneratePress on the exact same test website without changing anything else. Here is how GeneratePress did:
- Had a performance grade of 87, 10 points greater
- Loaded in 666 ms, ~37% faster
- Had a page size of 26.8 kB, ~90% smaller
- Had 9 requests, ~40% fewer
If You do that same test with different themes, you'll continue to find that GeneratePress is among the fastest-loading WordPress topics in life. Best WordPress Theme Viral
Other Useful Premium Extensions, Plus A Modular Approach
Beyond Giving you more style controls from the WordPress Customizer, GeneratePress Premium also comes with a lot of other useful features such as:
- Elements — a exceptional feature that lets you create custom hooks, page headers, or design templates.
- Page Header — allows you create a unique page header onto a per-page basis.
- Sections — that is kind of like lightweight page construction. It permits you to create different"sections" onto a page, each with their own design and column settings.
To Remain lightweight, GeneratePress also gives you a modular port where you could pick and choose what features you want to trigger.
That Way, you don't need to slow down your site for a quality which you'll never use.
Pre-Made Starter Sites Make It Easier To Design Your Website
In The last, you needed to build GeneratePress websites from a blank canvas regardless of what, which made the theme difficult for casual users to install.
Earlier In 2018, though, the programmer added a fresh Site Library attribute for GeneratePress Premium users that lets you easily import any among those 25+ pre-built demonstration websites .
You Can import them directly from the WordPress dashboard.
Yes this site still uses GeneratePress! All I did was click on a few buttons to import a demo site.
Page-Level Settings Provide You Comprehensive Control Over Each Bit Of Content
With Most themes, each page and post will use the same configurations for the most part. You might have some custom formats or templates — but you do not have very much control beyond that.
GeneratePress Changes that by providing you a new Layout meta name box for every single post and page:
You Can use this meta box to:
- Change the number of sidebars your site uses, or the sidebar orientation (like altering the sidebar from right to left)
- Choose the number of footer widgets to use
- Disable certain components, such as your header, navigation menu, article featured image, post title, or footer
- Create a special"container" to your own page builder
Where These controls would be the most useful is if you're using a WordPress page builder.
By Disabling certain components, you are able to create the correct baseline for your own page builder layout, making it easy to create custom articles as needed. Best WordPress Theme Viral
GeneratePress Pricing: Affordable And Works On Unlimited Sites
The Heart GeneratePress theme is available at no cost at WordPress.org.
Nevertheless, If you are seriously interested in utilizing GeneratePress, I feel you need to buy the GeneratePress Premium plugin, as that's what makes the theme so elastic. The free version does not give you nearly as numerous configurations from the WordPress Customizer. And you'll also lose out on the premade Site Library.
GeneratePress Premium is also still fairly affordable. It costs just $39.95, which gives you use on unlimited sites. You will also get a 40% discount if you would like to renew to continue receiving support and updates after the first year (you can, obviously, keep using GeneratePress after the initial year without renewing — you won't get any more updates).
When You believe that the normal premium WordPress theme will often cost around $60, GeneratePress provides a fantastic price.
As I mentioned, I do not believe GeneratePress is for everybody.
If You want a niche-specific motif, you can probably save time by purchasing a theme that fits your needs for your market from day one.
But If you are ready to spend some time altering preferences, then GeneratePress' mode controls give you the flexibility to turn it into any type of WordPress site. Or, you may even be able to find a starter website that fits your needs to save a little time.
Additionally, It's one of those fastest-loading WordPress topics you will locate. Therefore, if you're looking for the best performance possible, using GeneratePress as your WordPress site's foundation is a good choice.
If You combine it with fast-loading hosting, you should have no problem making your website load in under one second. Best WordPress Theme Viral
To Begin, Click here to download GeneratePress.


text:
All-optical transmission of two-dimensional images through a single single-mode fiber with a two-dimensional multicolor surface-emitting laser array and a volume hologram is described. A preliminary experimental result to prove the concept of the idea is demonstrated by transmitting a simple 2 × 2 image over a distance of 1 mile (1.61 km).
© 1992 Optical Society of AmericaFull Article | PDF Article
OSA Recommended Articles
Anthony M. Tai
Appl. Opt. 22(23) 3826-3832 (1983)
Anthony M. Tai and A. A. Friesem
Opt. Lett. 8(1) 57-59 (1983)
A. A. Friesem and U. Levy
Opt. Lett. 2(5) 133-135 (1978)


text:
Where: Sydney Conservatorium of Music, Recital Hall West
Improvisation is at the heart of most musical cultures. It is the activity of making new music – the articulation of prepared and unprepared musical statements and responses in real time. Join this mini lecture to find out how we can support you to develop your own unique musical language.


text:
A guitarist originating in South Florida, Michael Bianco is an accomplished guitarist well-known for his immense skill in the fingertapping style of guitar-playing.
Michael uses fingertapping to compose songs, often integrating rhythm and lead into one fluid harmony. Michael's influences include Stanley Jordan and the late, great Michael Hedges. As with Michael Hedges, Bianco's music is often described by terms like New Age and Ambient. Thus, anyone who enjoys Hedges' amazing music would undoubtedly appreciate Bianco. Bianco cannot be confined to these categories, however, for he incorporates a plethora of styles.
Also an accomplished Chapman Stick player, Michael designed the rare 14-string double neck guitar, built by Bob Mason, a guitar-maker also originating in South Florida.
In his early years, Michael attended the Berklee School of Music in Boston. After some time, Michael participated in several different bands, as many young musicians will. It wasn't until he moved to South Florida and actually decided to take a break from guitar, however, that he began his new career as a tapper. During this brief period of musical inactivity, Michael saw a video of Stanley Jordan, and was greatly inspired. He went on to do much experimentation with the tapping style, and has since created his own very unique musical form, making use of strumming, fingerpicking, and most of all fingertapping.
http://www.michaelbianco.com --Official Michael Bianco Website
Log in or register to write something here or to contact authors.
Sign up
Need help? firstname.lastname@example.com


text:
After the ball drops on New Year's Eve, 7-Eleven drops their price of coffee to zero.
It's a holiday tradition for the convience chain, giving away coffees, cappuccinos, and hot chocolate between midnight December 31st, 2008 and 6 a.m. New Year's Day.
You'll be able to tell which 7-Eleven locations are participating by checking the front window -- they'll have a poster with all the details.


text:
amyronemakeup needed a new logo design and created a contest on 99designs.
A winner was selected from 43 designs submitted by 16 freelance designers.
I am a hairstylist. I do color and cut. My target market is 35-45 woman that has a minimalist, clean, touch of boho chic/shabby chic, style. She is sophisticated, and also likes the outdoors. Shops at places like Michael Kors, Nordstrom, Target, Columbia outer wear, and styles her home after Magnolia Market style.
I am wanting something different. A lot of fellow stylist have been getting logos that are a some kind of circle with their name written in the middle with some vines or flowers on the circle. I don't want that. I'm looking for something original, but not cheesy or cheap looking either. A sophisticated rustic style. No scissors or any other cliche hairstylist items. Maybe a Venus seashell or something else that is a symbol of beauty (beautified)...?
Find out how a design contest works or learn more about our logo design services.