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Professional Makeup For Beginners
Make-up For Beginners
Make-Up for Beginners: Learn Doing Make-Up like a Pro is an online course created by Lana Vallo. It helps individuals do their makeups in a professional way such that they are durable, last for long and enhance beauty. It transforms you into an expert that other people will turn to for help over and over. Subscribing to this program guarantees you more beautiful than ever before. The course was designed following an increasing demand for brand-neutral, timely, and professional advice on the skill of makeup. Enrolling to the course does not require any special tool or requirements. Nonetheless, once you are done with the sessions you will require professional makeup brushes and other necessary tools including a complete makeup kit. It will also be necessary that you find a model for putting into practice all the strategies covered by the video tutorials, especially if you aspire to do makeups for other individuals. This is a fantastic program with thousands of positive reviews. It will significantly improve your skills and make you an expert in the makeup industry. Payment is processed via ClickBank and the product has a 60-day warranty. Read more here...
Makeup For Beginners Summary
Contents: Online Course
Author: Lana Vallo
Official Website: courses.glowmakeup.com
My Makeup For Beginners Review
I've really worked on the chapters in this ebook and can only say that if you put in the time you will never revert back to your old methods.
All the modules inside this ebook are very detailed and explanatory, there is nothing as comprehensive as this guide.
Genetic Makeup and Gene Structure
Vesiculoviruses exemplify one of the simplest genome architectures among the Mononegavirales. The entire CHPV genome has been sequenced and comparison with other vesiculoviruses has confirmed similar genetic makeup among vesiculoviruses. The Chandipura virus RNA genome comprises a 49-nt long leader sequence (l), followed by five transcriptional units coding for viral polypeptides separated by intergenic, nontranscribed spacer regions, and a short nontranscribed trailer sequence (t) arranged in the order 3' l-N-P-M-G-L-t 5' (Figure 1(c)). The CHPV gene junctions encompass a 23-nt long sequence that is highly conserved among different vesiculoviruses this conserved sequence is comprised of a 11-nt gene end signal that regulates transcription termination and polyadenylation of viral mRNA, a 2 nt nontranscribed spacer region, and a 10 nt conserved promoter element that has been implicated in
Decorative Cosmetics Sunscreens Toiletries Tables 4 and
Table 4 .Testing of decorative cosmetics and sunscreens. Abbreviations for vehicles in the following tables ac acetone, MEK methyl ethyl ketone, oo olive oil,pet petrolatum, w water Table 4 .Testing of decorative cosmetics and sunscreens. Abbreviations for vehicles in the following tables ac acetone, MEK methyl ethyl ketone, oo olive oil,pet petrolatum, w water
Dimethylaminopropylamine is an aliphatic amine present in amphoteric surfactants such as liquid soaps and shampoos. It is present as a residual impurity thought to be responsible for allergy from cocamidopropylbetaine. It is structurally similar to diethyl-aminopropylamine. It is also used as a curing agent for epoxy resins and an organic intermediate in chemical synthesises (ion exchangers, additives for flocculants, cosmetics and fuel additives, dyes and pesticides). Patch test has to be carefully interpreted, since the 1 aqueous solution has pH ii (personal observation).
Water And Wastewater Disinfection Treatment
The fourth and final disinfection mechanism is that of altering and disrupting a cell's genetic makeup so that the cell is prevented from reproducing even though it may still have the energy to do so. This disinfection effect is largely associated with the use of ultraviolet irradiation, and its consequent high-energy cross-linking of adjacent nitrogen base groups poised side by side at various points within stranded DNA (see the thymine dimer reaction in Figure 16.54). The resulting impact of polymerizing DNA and formation of thymine dimers follow much the same path, such that cells are effectively sterilized by this UV exposure.
Supercritical Fluid Extraction SFE
Extraction and separation processes are basic industrial operations applied in many areas with considerable economic relevance. Supercritical fluids, especially carbon dioxide, are of increasing interest for new separation processes in the fields of foodstuffs, cosmetics and pharmaceuticals.
PVPEicosene Copolymer
PVP eicosene copolymer is the polymer of vinylpyrrolidone and of 1-eicosene, and one of the 11 PVP copolymers recorded in the International Nomenclature of Cosmetics Ingredients inventory system. This substance is utilized in cosmetics, in sunscreens to enhance their water resistance, and is an inert ingredient in pesticides. Contact sensitization to a close compound VP eicosene co-polymer was also reported.
Hexamethylene Diacrylate
Kanerva L, Estlander T, Jolanki R, Tarvainen K (1993) Occupational allergic contact dermatitis caused by exposure to acrylates during work with dental prostheses. Contact Dermatitis 28 268-275 Kanerva L, Lauerma A, Estlander T, Alanko K, Henriks-Eckerman ML, Jolanki R (1996) Occupational allergic contact dermatitis caused by photobonded sculptured nails and a review of (meth) acrylates in nail cosmetics. Am J Contact Dermat 7 109-115
Genetic Testing and Alzheimers Disease
The Ames test is widely used by the pharmaceutical industry to test drugs prior to using them in clinical trials. When a drug is mutagenic in the Ames test, it is usually rejected for further development and will probably not be tested in animals or used therapeutically in humans. The cosmetic industry also uses the Ames test to assess the mutagenic potential of makeup and other hygienic products. The Food and Drug Administration requires companies to perform the Ames test before marketing most drugs or cosmetics. see also Cancer Carcinogens Mutagen Mutagenesis Mutation Nucleotide.
Angioedema and Urticaria
INTRODUCTION Angioedema and urticaria are common transient phenomena that result from mast cell degranulation with the release of mediators that promote vascular permeability, causing proteins and fluids to extravasate into the extracellular space. In urticaria fluid collects within the dermal tissue, whereas in angioedema fluid collects in the deeper subcutaneous space. The causes of mast cell degranulation are varied and include both immunologic and nonimmunologic mechanisms. Systemic involvement may include rhinitis, bronchospasm, or anaphylaxis. Severe reactions may lead to syncope, bronchial asthma, and hypotension. In rare cases both urticaria and angioedema may be triggered by exercise. Acute cases reach a peak in one to three days and usually fade in 7-21 days. In chronic cases the condition waxes and wanes for months or may even persist for years. There may be recurrent attacks separated by months to years. Inciting allergens are numerous and include foods, cosmetics,...
Woodsia polystichoides
Culture and comments Easily introduced to the sunny, fern-forbidding sites of rock gardens, holly fern woodsia cheerfully cascades and meanders among the rocks and keeps company with alpine fellow travelers. My garden plants are in neutral to slightly acid grit, with slick drainage and exposure more critical than soil makeup.
Transient Global Amnesia
Decline in Personal Hygiene and Grooming. The caregivers' accounts of failure to wash, bathe, groom, apply makeup, and dress appropriately as before are reinforced by clinical observations of unkemptness, body odor, clothing stains, garish makeup, and inappropriate clothing combinations.
Pest Impact Assessment
The mere occurrence of an insect species in association with a crop or a farm animal does not necessarily mean that the species is a pest of that crop or animal. To be a pest it must cause economic losses. The assessment of economic losses from pests is the subject of studies conducted under conditions that match as closely as possible the conditions under which the crop is grown commercially or the animals are raised. Much of the methodology used in crop loss assessment has been established under the sponsorship of the Food and Agriculture Organization (FAO) of the United Nations as a means of prioritizing budget allocations and research efforts. Key data for these studies relate to the determination of the yield potential of a crop. The genetic makeup of a crop variety determines its maximum yield in the absence of adverse environmental factors. This is known as the attainable yield. To determine the attainable yield, the crop is grown under nearly ideal conditions the actual yield...
Pharmacogenetics and Pharmacogenomics
The complete sequencing of the human genome in 2000, along with new technologies, such as DNA microarrays, for analyzing human genes on a genome-wide scale, provides scientists with the tools to study the molecular basis of diseases on a level and scale that previously had not been possible. Pharmacogenomics is a biomedical science that aims to use this knowledge to tailor drug therapies based on patients' individual genetic makeup. Doctors hope to use pharmacogenomics to develop safer and more effective medical treatments. For some diseases, this promise has already been realized.
Microdistribution None
Light applications of liquid nitrogen sufficient to produce a 0.5- to 1-mm rim of freeze at the perimeter of the base of the SK is usually sufficient for total removal. The advantage of this technique is the absence of scarring. Heavily pigmented persons must be warned about the possibility of posttreatment hyper- or hypopigmentation. This is especially important when working on the facial area. When patients express concern in this regard, we encourage treatment of one or two test lesions in an inconspicuous location before proceeding. During the sunny season, we strongly urge sun avoidance and the use of a sunscreen with makeup to prevent posttreatment darkening. Cryosurgery is the appropriate way to treat these lesions.
Pglycoprotein Gene Polymorphisms And Their Implications In Drug Therapy And Disease
Digoxin and higher plasma drug levels. These results, however, were later contradicted by those of other groups. A recent metaanalysis suggested that the C3435T SNP has no effect on the expression of MDR1 mRNA or the pharmacokinetics of digoxin.211 Conflicting data have been reported on the effects of other alleles using various drug substrates, and the controversy seems likely to continue. The differential effects of Pgp polymorphisms on Pgp expression and drug disposition will probably not be resolved until progress is made in standardizing parameters such as sample size and makeup, environmental factors, and the assays used for Pgp protein and mRNA quantification. MDR1 haplotypes, rather than individual SNPs, are also more likely to affect the pharmacokinetics of MDR1 substrates. Two common Pgp polymorphisms (G2677T A and C3435T) may play a role in the differential response to the cholesterol-lowering statin drugs.212 When haplotypes were also considered, a subgroup of female...
Medicinal Hamamelidaceae
The family Hamamelidaceae consists of 26 genera and about 100 species of shrubs or tress known to contain tannins and iridoids. The leaves are alternate, simple, and often palmately lobed. The flowers are small and appear in spikes. The fruits are woody, capsular, and scepticidal. In Western medicine, the dried leaves of Hamamelis virginiana (hamamelis, British Pharmaceutical Codex, 1963), yielding not less that 20 of alcohol (45 )-soluble extractive, have been used as astringents for the treatment of hemorrhoids. Hamamelis water (British Pharmaceutical Codex, 1969) made from the stems has been used as a cooling application to sprains and bruises and as a styptic remedy. It is also used in cosmetics and as active ingredient of eye lotions.
Haralambos Stamatis Vasiliki Sereti and Fragiskos N Kolisis 1 Introduction
Fatty acid monoesters and diesters of sugars are widely used as emulsifiers in a great variety of food and cosmetics formulations (1). Traditionally, these surfactants are produced by transesterification at high temperatures in the presence of an alkaline catalyst. Among drawbacks of the conventional chemical process, significant coloration of the final product and the formation of undesirable side products are especially worth mentioning. Consequently, the enzyme-catalyzed regioselective acylation of sugars in nonpolar organic solvents and supercritical fluids (SCFs) at ambient temperatures has received much attention in recent years (2-5).
Future Perspectives
It is interesting to note that the enteroviruses, originally established on provisional bases, now appear to form a 'real' genus, in which the members are indeed related in fundamental ways. The original grouping was based on small size (about 27 nm), an RNA genome, resistance to ether and mild acid and an enteric habitat. The grouping has been validated by studies utilizing sophisticated techniques of modern molecular virology that allow us to compare the genetic makeup of these viruses and details of their structure and their mode of replication.
Genomics And Proteomics
The amount of DNA sequence data available and the methods used to exploit it have grown exponentially in recent years. The aim of this work is to understand how the various components of an organism interact to function properly, not just to catalogue a list of genes and how they function. Genomics describes the study of the genetic makeup of an organism, whereas proteomics is the study of the protein composition of the cell. There are more proteins in an organism than there are genes because transcriptional control, posttranslational modification, and so on can lead to multiple products form the one gene hence the need to study the interrelationship between genomics and proteomics, which is termed functional genomics.
Comparison Of Viral Load Assays
Log variation in the detection of some strains. 10 The choice of method for quantification is dictated by throughput of samples and the genetic makeup of the patient cohort. There is an urgent requirement for international standards which should include non-clade B strains to enable quality control of viral load measurements.
Microbial Taxonomy 1041 Basis of Identification
Precise characterization of DNA and RNA sequences is now being used extensively to determine relationships among organisms. Such analysis of an organism's genetic makeup reveals its genotype. Genotype obviously affects phenotype, but not all genetic capabilities are necessarily expressed in an organism at a particular time. As might be expected, knowledge of genotypes has greatly increased and modified our understanding of the relationships among microorganisms. In fact, the separate domain of Archaea was not recognized until these newer tools were applied previously, they were simply considered types of (and may still often be referred to out of habit as) bacteria.
Public Health Approaches in Genetics
Common chronic diseases such as cancer and heart disease. Risk for almost all human diseases results from the interactions between inherited gene variants and environmental factors, including chemical, physical, and infectious agents, as well as behavioral or nutritional factors. Thus it appears reasonable to direct disease-prevention and health-promotion efforts toward individuals at high risk because of their genetic makeup.
Ethical And Social Aspects Of Genetic Profiling
Genetic profiling for pharmacogenetic purposes is less likely to raise objections than genetic testing for primary disease risk assessment. Nevertheless, ethical issues concerning patient confidentiality, possible misuse of geno-typing data, and possible harm to patient's social and insurability status need to be resolved before the implementation of pharmacogenetics in healthcare. Holding sensitive information on someone's genetic makeup raises questions of privacy and security and ethical dilemmas in disease prognosis and treatment choices. After all, polymorphisms relevant to drug response may overlap with disease susceptibility, and divulging such information could jeopardize an individual. On the other hand, legal issues may force the inclusion of pharmaco-genetic information into clinical practice. Once the genetic component of a severe adverse drug effect is documented, doctors may be obliged to order the genetic test to avoid malpractice litigation.
Inhibitors Of The Ras Pathway
What, then, is the preferred point of intervention in the RTK Ras Raf MEK ERK MAP kinase CDK Rb pathway A number of factors influence this selection, including issues of technical feasibility, extent of validation and proof principle, and the potential for therapeutic selectivity. One argument claims we should seek to interfere as closely as possible to the point of molecular deregulation, e.g., at the overexpressed RTK, the mutated Ras, or the deregulated CDK. This may provide maximum pharmacological selectivity, since the therapy would be tailored to the particular genetic makeup of the individual tumor.
Oral ingestion studies
The bioactivity of a toxicant ingested varies with the frequency, presence of food, and the makeup of the food, such as amount of purified sugar, fiber, high protein, or high fat. The different pH conditions of the gastrointestinal tract affect the ionization of weak organic acids and bases. Following absorption in the gastrointestinal tract, the bioactive chemical is translocated to either the lymphatic system or the portal circulation. The portal circulation directs the chemicals to the liver, and many of the chemicals are excreted by the liver as bile. Because the bile empties back into the intestine, a cycle involving translocation of the chemical from the gastrointestinal tract to the liver and via the bile back to the intestine occurs. This cycle is known as enterohepatic circulation. Ingestion of chemicals from the gastrointestinal tract and enterohepatic cycle exposes the liver to those concentrations of the agent that would not be obtained by other exposure routes, such as...
Culture Media And Upstream Components
The ideal culture medium will use inexpensive components to supply their complex nutrient requirements. Miller and Churchill (13) provide an excellent summary of inexpensive media components and their makeup. These ingredients are crop, animal, marine or yeast based components. The culture medium alone can represent 30 to 70 of the fermentation production costs. Slight changes in medium micronutrients can have a major impact on the fermentation (14,15). Thus, the food industry demands a consistent product from suppliers of these complex components. Failure to provide a consistent product will eliminate the commercial use. What decides the culture medium makeup Essentially, it is the nutritional requirements of the microorganism of choice and its ability to biosynthesize essential elements such as amino acids, vitamins, lipids, and carbohydrates. For example, bacteria and yeast are high in protein (40-50 ), whereas molds are not (10-25 ). Yeast
Plant Cell Cultivation
Stirred tank fermentors have also been used for the growth of plant cells for the production of valuable products in single or multiple stages of cultivation. Plant cell culture is carried out by propagation of a callus, which is a mass of undifferentiated cells. To develop a new plant with shoot and root, cells from the callus must be cultured in different media. Desirable metabolites can be extracted from a callus without progression to a shoot and root. Plant cell culture may serve as a good medium for synthesis of metabolites useful in foods, biopesticides, and cosmetics. Plant cell culture has been proposed as an alternative technique for the supply of phytochemical to the normal plantation system (160). The benefits of such a system include a final product of required quality and consistency independent of the variations in plantation due to season, weather, disease, and pest destruction. Cultivation of plant cell suspensions in bioreactors has led to higher productivity of the...
Regulatory Process And Requirements
The FDA is a subcabinet organization within the Department of Health and Human Services (HHS) which is one of the major cabinets in the United States government. The FDA is headed by a commissioner with several deputy or associate commissioners to assist him or her in various issues such as regulatory affairs, management and operations, health affairs, science, legislative affairs, public affairs, planning and evaluation, and consumer affairs. Under the office of commissioner, there are currently six different centers of various functions for evaluation of food, drugs, and cosmetics. They are Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), Center for Devices and Radiological Health (CDRH), National Center for Toxicological Research (NCTR), Center for Veterinary Medicine (CVM), and Center for Food Safety and Applied Nutrition (CFSAN).
History Of Clinical Trials
In 1906, the United States Congress passed the Pure Food and Drug Act. The purpose of this act is to prevent misbranding and adulteration of food and drugs. However, the scope of this act is rather limited. No preclearance of drugs is required. Moreover the act does not give the government any authority to inspect food and drugs. Since the act does not regulate the claims made for a product, the Sherley Amendment to the act was passed in 1912 to prohibit labeling medicines with false and fraudulent claims. In 1931, the U.S. Food and Drug Administration (FDA) was formed. The provisions of the FDA are intended to ensure that (1) food is safe and wholesome, (2) drugs, biological products, and medical devices are safe and effective, (3) cosmetics are unadulterated, (4) the use of radiological products does not result in unnecessary exposure to radiation, and (5) all of these products are honestly and informatively labeled (Fairweather, 1994). The concept of testing marketed drugs in human...
The Role of Host Genes in Determining the Phenotype of Autoimmune Disease
Determine which organs or tissues are targeted by the responses 52, 53 . The genetic makeup of the host mainly determines the phenotype of the autoimmunity triggered by altered T cell regulation. For example, NTx predominantly produces autoimmune oophoritis in the A strain, autoimmune gastritis in the BALB c but not DBA 2 strain (which shares the H-2d MHC haplotype), and no apparent organ-specific autoimmunity in the C57BL 6 strain 53 . Administration of neutralizing anti-IL-2 mAb produced gastritis in BALB c mice, exacerbated T1D in NOD mice 25 , and produced de novo autoimmune peripheral neuritis in NOD mice 25 . ATx and subsequent fractionated X irradiations predominantly induces thyroiditis in PVG c rats with the RT1c MHC haplotype, and T1D in MHC congenic PVG-RT1u rats 54 . Thus, MHC and non-MHC genes contribute to determining the phenotype of autoimmune disease triggered upon reduction or dysfunction of natural Treg. Polymorphisms of these genes may affect the formation of a...
Protecting the Public Health
The FDA is responsible for not only drugs and biologics, but their regulatory authority also extends to food, medical devices, veterinary drugs, cosmetics, nutrition products, and radiation devices. Thus, they are responsible for protecting the health of the nation's citizens across a broad spectrum, including such areas as labeling of the nutritional content on food, approving only drugs found to be safe and effective for human or veterinary use, the allergenic potential of cosmetics, and the certification of mammography equipment. FDA further interprets new laws from Congress and promulgates regulations and guidelines for the industry to follow.
Why Study Quantitative Theories
Sometimes we may formulate a model in a very abstract, nonbiological way, for example, to study how variation in rates of transition between stages influences age-onset patterns. In this case, stages remain abstract notions that we manipulate in a mathematical model in order to understand the logical consequences of various assumptions. In other cases, we may try to match the definition of stages and rates to the biological details of a particular cancer. A stage may, for example, be an adenoma of a particular size, histology, and genetic makeup. A transition between stages may occur at the rate of a somatic mutation to a particular gene.
Raising A Child Conceived With Donor Material
In the case of donor sperm, eggs, or embryos, you'll also need to decide if you want to explain this to your child. If you do decide to be open about the conception, consider how much information to share with the child. Some people choose to portray the donor in the same way as a biological parent who placed the child for adoption. Others explain that the donor was more of a helper who assisted in conception but has no further role. At some point, will the child be able to find out about the donor Should they meet and form a relationship Many agencies keep this information on file, and so it may become available to the child once he or she reaches age 18. Ideally, this type of information should be spelled out in your donor agreement prior to conception. At the very least, the child should know about the donor's medical history because it is part of the child's genetic makeup and medical family history.
Lowpolarization Surface Electrodes
Warning The materials used to form Ag AgCl electrodes are relatively dangerous. Do not breathe dust or mist and do not get in eyes, on skin, or on clothing. When working with these materials, safety goggles must be worn. Contact lenses are not protective devices. Appropriate eye and face protection must be worn instead of, or in conjunction with, contact lenses. Wear disposable protective clothing to prevent exposure. Protective clothing includes lab coat and apron, flame- and chemical-resistant coveralls, gloves, and boots to prevent skin contact. Follow good hygiene and housekeeping practices when working with these materials. Do not eat, drink, or smoke while working with them. Wash hands before eating, drinking, smoking, or applying cosmetics.
The Maturational And Biological Models
Gesell also made significant contributions with the development of the co-twin method for comparing the relative effects of heredity (nature) and environment (nurture) on development. One identical twin would receive specific training in some skill (such as stair climbing), and the other twin would receive no training in the skill. The rationale for this strategy was that because the children had an identical genetic makeup, any difference in stair-climbing ability must be the result of training. This is the basic paradigm that Gesell used to question some very interesting and controversial statements about the nature of intelligence.
Laboratory Animal
The use of laboratory animals creates an ethical dilemma for humans, offering the possibility of improvements for human health but also causing possible pain* and discomfort to animals. One result of this dilemma has been a growing resolve to find alternatives* in research, teaching, and testing. At the same time, finding alternatives has become an established goal of many organizations and has been enacted as a requirement in some legislation. This idea that it is desirable to develop new methods reflects changing attitudes toward animals. More and more people, both inside and outside the scientific community, have come to believe that it is worth considerable effort and cost to reduce discomfort of laboratory animals. This shift in consciousness was accelerated by publicity concerning the Draize test in rabbits (see ACTIVISM FOR ANIMALS), which was used to test new cosmetic and pharmaceutical products for eye and skin irritancy. Henry Spira's concerted campaign begun in 1979 against...
Cinnamic Alcohol 3Phenyl2Propenol CAS Registry Number [104541
Cinnamyl alcohol occurs (in esterified form) in storax, Myroxylon pereirae, cinnamon leaves, and hyacinth oil. It is obtained by the alkaline hydrolysis of storax, and prepared synthetically by reducing cinnamal diacetate with iron filings and acetic acid, and from cinnamaldehyde by Meerwein-Ponndorf reduction with aluminum isopropoxide. Cinnamic alcohol is contained in the fragrance mix. As a fragrance allergen, it has to be mentioned by name in cosmetics within the EU. Occupational cases of contact Citral is an aldehyde fragrance and flavoring ingredient, a blend of isomers cis (Neral) and trans (geranial). As a fragrance allergen, citral has to be mentioned by name in cosmetics within the EU.
Susceptible Responses
Disease responses vary dramatically depending on the virus-host combination under investigation. The type of response, for example chlorotic versus necrotic symptoms, is generally dependent on the genetic makeup of both the plant and the infecting virus. However, environmental factors such as the availability of micronutrients, nitrogen, water and light can also have significant effects on the severity of the observed disease. Additionally, the developmental stage of a plant or leaf at the time of infection can also determine the type of disease response. For example, Matthews and colleagues determined that for tobacco leaves infected with TMV the critical leaf size at which mosaic symptoms develop is at or below 1.5 cm in length. Leaves that were developmentally larger when inoculated failed to display the mosaic
Concluding Remarks
Our current understanding of the discrete steps of the CHPV replication cycle relies on the studies being conducted on the CHPV as well as on other vesiculoviruses. Remarkable similarities between CHPV and VSIV in genetic makeup, gene structure, polypeptide composition as well as function allow the postulation of a generalized model to describe vesiculovirus transcription at the molecular detail. While the proposed mechanism for
Unknown Effects on Human Health
In the U.S., the regulatory process is confused because three different government agencies have jurisdiction over GM foods. To put it very simply, the EPA evaluates GM plants for environmental safety, the USDA evaluates whether the plant is safe to grow, and the FDA evaluates whether the plant is safe to eat. The EPA is responsible for regulating substances such as pesticides or toxins that may cause harm to the environment. GM crops such as Bt pesticide-laced corn or herbicide-tolerant crops but not foods modified for their nutritional value fall under the purview of the EPA. The USDA is responsible for GM crops that do not fall under the umbrella of the EPA, such as drought-tolerant or disease-tolerant crops crops grown for animal feeds or whole fruits, vegetables, and grains for human consumption. The FDA historically has been concerned with pharmaceuticals, cosmetics, and food products and additives, and not whole foods. Under current guidelines, a GM ear of corn sold at a...
Discharge And Home Healthcare Guidelines
Protection factor of greater than 15 before going outdoors. Apply sunscreen on cloudy days because roughly 70 to 80 of ultraviolet rays can penetrate the clouds. Reapply sunscreen every 2 to 3 hours during long sun exposure. Be aware that the sun's rays are reflected by such surfaces as concrete, snow, sand, and water, thereby increasing exposure to ultraviolet rays. Wear protective clothing when outdoors, particularly a wide-brimmed hat to protect the face, scalp, and neck area. Wear wrap-around sunglasses with 99 to 100 ultraviolet absorption to protect the eyes and the skin area around the eyes. Be aware of medications and cosmetics that increase the sensitivity to ultraviolet rays. Minimize ultraviolet exposure as much as possible and use sunscreen that contains benzophenones. Avoid tanning booths or sunlamps.
Genetic Characteristics of Founder Populations
Because the founder population is small, genetic drift can play an important role in determining the genetic makeup of subsequent generations, and allele frequencies may fluctuate. For example, consider an extreme situation where a new population is founded by just two individuals, a male and a female, perhaps because they are stranded on an island. Assume that the
Error Prone Replication and Quasispecies
Also led to some counter intuitive conclusions, such as the concept of selection of 'the fittest' compared to the consensus character of the master template. Quasispecies from a virus with high error rates (such as HIV-1) might be composed of all mutant progeny RNAs such that the consensus template (the mean, the fittest, or the master template) may not actually exist. With classical population genetics, an asexual clonal population should fix the clonal sequence. With quasispecies, this is not observed. The first laboratory measurements of viral quasispecies were made using Qp RNA polymerase in vitro. Error estimates ranged from 10 3 to 10_ substitutions per site per year (an error rate applicable to most RNA viruses). With Qp, the replication of many nonviable mutants generated a genetic spectra that had a characteristic makeup. For example, separate DNA clones of Qp were initially distinct from each other but quickly generated the same RNA quasispecies as before cloning. Additional...
Advantages of DNA Comparisons
There are several advantages to comparing DNA data instead of external physical characteristics (collectively called the phenotype). Environmental factors can shape the phenotype to make two individuals with the same genetic makeup look different. For instance, nutrition has a profound effect on height, and if we used average height to classify humans, we might mistakenly conclude that medieval humans represented a different subspecies because they were significantly shorter than modern humans. DNA comparisons, on the other hand, would show no significant difference between these groups.
Genomewide effectschromosome rearrangements
She also recognized the very important set of responses to challenges that were not hard-wired into the genomic makeup of organisms. In this regard she observed that 'An experiment conducted in the mid-1940's prepared me to expect unusual responses of a genome to challenges that the genome is unprepared to meet in an orderly, programmed manner.' McClintock suggested that one such response could result from the genomic shock associated with crosses between divergent evolutionary lineages (e.g. Y.-M. Wang et al. 2005). Specifically with regard to the present topic she stated, 'Major restructuring of chromosome components may arise in a hybrid plant and continue to arise in its progeny, sometimes over successive plant generations. The restructuring may range from apparently simple to obviously complex' (McClintock 1984).
Solid Waste Treatment
Highest level of potential degradability, due to both their organic makeup and their high water content. Cellulose-rich residues, whether discarded as lawn clippings or paper products, would also be amenable to biochemical degradation, although perhaps at a somewhat slower rate. Extending beyond these two segments, though, municipal solid waste includes many other materials whose composition will not be amenable, and possibly even antagonistic or inhibitory, to biochemical degradation. For example, MSW generated within affluent countries includes a sizable proportion of plastic, for which the vast majority will have no susceptibility to biochemical breakdown. Similarly, affluent countries generate municipal solid wastes with a proportionately higher percentage of metals (e.g., cans, batteries, used appliances) whose presence may actually lead to the release via leaching of soluble heavy (e.g., cadmium, chromium, nickel, lead) and transition (e.g., arsenic, selenium) metal ions that...
Genomics Of Dairy Cultures
Currently, there are three complete genomes from dairy cultures that have been sequenced and published. These are for Lactococcus lactic IL1403 (177), Bifidobacterium longum NCC2705 (178) and Lactobacillus johnsonii NCC533 (179). A fourth genome from L. plantarum WCFS1 (180) may also be of interest as it is sometimes speculated to be a potential probiotic culture. The L. lactis IL1403 genome was the first one published and it provided an exciting glimpse into the makeup of a lactococcal chromosome and the evolution of this organism. Remnants of a once aerobic existence are evident, and a set of genes analogous to the natural competence genes in Bacillus. While analysis of the L. lactis IL1403 genome does give intriguing information, it does not shed light on many of the commercially significant phenotypes, as these are largely encoded on plasmids, and IL1403 is a plasmid cured laboratory strain. Therefore, as part of the LABGC effort a commercial strain of L. lactis subsp cremoris...
TREATMENT Patients should understand that this condition will likely be a life-long problem that can be controlled, but seldom eliminated. The main goals of treatment are to reduce meibomian gland inflammation and to reduce increased tear osmolality. Eyelid cosmetics may be an aggravating factor and should be avoided for a time. Scalp seborrhea must be controlled with 1 selenium sulfide shampoo, and a baby or no tears shampoo can be used for lid scrubs. Scales and crusts should be soaked and removed daily with cotton-tipped applicators or a moist washcloth wrapped around a finger. Cultures of the lid margins and of material expressed from the meibomian glands should be obtained for antibiotic sensitivities prior to starting topical antibiotics to suppress the bacterial growth. Preferred anti-infective agents in topical ointment form are bacitracin, sulfacetamide, and erythromycin. In the most severe cases a short course of systemic antibiotic, preferably a semisynthetic penicillin,...
Octocrylene is an anti-UVB filter used in cosmetics that may induce photoallergic contact dermatitis. Octyl gallate, a gallate ester (E 311), is an antioxidant added to foods and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were sparsely reported in food industry or from lipsticks. Patch tests are frequently irritant.
NETTLE juice combed through the hair to prevent baldness has been a common folk practice (Baker). The Wiltshire cure for dandruff was to massage the scalp with a nettle infusion each day (Wiltshire). PARSLEY was recommended for baldness as far back as Pliny's time (Bazin), repeated a long time afterwards as powder your head with powdered parsley seed three nights every year, and the hair will never fall off (Leyel. 1926). Actually, it really does make a good lotion for getting rid of dandruff, and helps to stave off baldness (A W Hatfield). ROSEMARY, besides providing the base of various hair rinses (see COSMETICS), was also used for the more serious purposes of preventing baldness. A manuscript from 1610 claims that if thou wash thy head with rosemary water and let it drye on agayne by itselfe, it causeth hayre to growe if thou be balde (Gentleman s Magazine Library Popular superstitions p162). Equally optimistic was a wash to prevent the hair from falling off , noted in the...
HOUSELEEK, probably because a growing plant in the thatch brought luck and order to the house NARCISSUS. The story of Narcissus, enamoured of his own beauty, becoming spell-bound in front of his own image, is too well-known for comment JASMINE GOLDEN ROD CAMOMILE, perhaps from the truism that the more it is trodden, the faster it grows PERIWINKLE, as in an old ballad, in which a noble lady is called the parwenke of proesse OPIUM POPPY, in Christian art (Ferguson). Presumably from the great number of its seeds ALKANET, for its roots, for making rouge, seem to be one of the most ancient of face cosmetics CARNATION
Genetic Diversity
The individuals that make up a population are rarely identical. Such variation in the outward appearance of individuals (i.e., in their phenotype) results from the interaction of their individual inherited genetic makeup (genotype) with their surrounding environment. Most natural populations maintain a high level of such genetic diversity. This inherited genetic variation is the basis upon which evolution operates, and without it adaptation and speciation cannot occur. Genetic diversity fundamentally occurs in the form of nucleotide variation within the genome, which originates by mutation (changes in the nucleotide composition of genes, in the position of genes on chromosomes, and in the chromosome complement of individuals) and is maintained both by natural selection and by genetic drift. Other forms of genetic diversity include the amount of DNA per cell and chromosome structure and number. It is estimated that there are 109 genes in the world, although some of the genes for key...
Types Of Color
A second basis for color is structural, caused by the interaction of white light with minute and precise arrays on or in the material. The effects depend on the architecture, rather than the chemical makeup of the material. Light may be reflected, refracted, or scattered, but it is not absorbed, and so structural colors are additive if two are combined, both sets of wavelengths are represented in the final effect. If all wavelengths of the visible spectrum are reflected, we call the sensation white. (Technically, white, even if caused by a pigment, is always a structural color, because it is the absence of any absorption of light.) Because the underlying architecture must generally be precise and stable, most structural colors are typically produced by stiff, nonliving materials, and of these insect cuticle is literally a brilliant example.
Enzyme Engineering
Enzymes have been used by humankind for millennia for a wide variety of biotechnological purposes, including the production of foodstuffs such as cheese, bread, wine, and beer. Currently, enzymes are used for a multitude of applications in a number of diverse areas ranging from detergent manufacturing to the production of fuels and pharmaceuticals, from food and feedstuff manufacturing to cosmetics production, as medicinal products, and as tools for research and development 3-8 .
Process Changes
Could give rise to significant environmental benefit. Biological synthesis, either by whole organisms or by isolated enzymes, tends to operate at lower temperatures and, as a result of high enzymatic specificity, gives a much purer yield with fewer byproducts, thus saving the additional cost of further purification. There are many examples of this kind of industrial usage of biotechnology. In the cosmetics sector, there is a high demand for isopropyl myristate which is used in moisturising creams. The conventional method for its manufacture has a large energy requirement, since the process runs at high temperature and pressure to give a product which needs further refinement before it is suitable for use. An alternative approach, using enzyme-based esterification offers a way to reduce the overall environmental impact by deriving a cleaner, odour-free product, and at higher yields, with lower energy requirements and less waste for disposal.
Hyperplastic Polyps
Hyperplastic polyps comprise a majority of all gastric polyps. Initially thought to makeup 75 or more of gastric polyps (1,27), they are probably the second most common polyp after FGPs. Hyperplasiogenic, regenerative, hyeprplastic-adenomatous, adenomatous polyps, inflammatory, and benign polyps are other names in the literature used for hyperplastic polyps. They affect men and women equally and tend to develop later in life than FGPs. They are small, dome-shaped or stalked polyps with an average size of about 1 cm (range
Carotenoids comprise a group of natural pigments that are ubiquitous throughout nature. Over 600 different carotenoids with diverse chemical structures have been identified in bacteria, fungi, algae, and plants (Shew-maker et al., 1999 Mann et al., 2000). Their colors range from yellow to red, with variations of brown and purple in addition, carotenoids as colorants take advantage of their good pH stability and their insensitivity to reducing agents such as ascorbic acid (Mann et al., 2000). Not to be outdone, humanity through the ages has learned to exploit the pleasing visual properties of carotenoid pigments by supplementing feedstocks and incorporating caro-tenoid pigments into cosmetics and foods (Delgado-Vargas et al., 2000 Jez and Noel, 2000). As precursors of vitamin A, they are fundamental components in our diet and play additional important roles in human health (Delgado-Vargas et al., 2000 Van den Berg et al., 2000 Ye et al., 2000). Because animals are unable to synthesize...
Genomics is a recent scientific discipline that strives to define and characterize the complete genetic makeup of an organism. Its primary approaches are to determine the entire sequence and structure of an organism's DNA genome the total (its genome) and then to determine how that DNA is arranged into genes.
Marsh Mallow
The roots are used in the cosmetics trade, but in France there is a more immediate use. Dried, and known as Hochets de Guimauve, they are sold in chemists' shops as teethers. They are hard and fibrous enough for a baby to chew on, but slowly soften on the outside as their mucilage is released (Mabey. 1977). There is one interesting piece of folklore. In the Isle of Man, marsh mallow was used (both internally and externally) to remove the result of walking or lying on bad ground , and bad ground meant ground affected by the fairies (Gill. 1963).
Skin Tests
Methodological details regarding dilution, vehicle, pH measurement, open test, closed patch test, repetitive open application test (ROAT), and use test are dealt with in Chap. 22. In Dortmund we found large Finn chambers (12 mm diameter) useful for testing cosmetics with low irritancy (e.g., moisturizers, lip cosmetics, sunscreens, eye drops 14 Fig. 1).
This emulsifying agent can be contained in many products such as cosmetics, topical medicines, metalworking cutting fluids, and color film developers. Traces may exist in other ethanolamines such as mono- and diethanolamine. Contact allergy seems to be rarer than previously thought.
Where the simplest preparation is still in use, in the Pacific islands and New Guinea, it serves mainly for cosmetics or for painting wood, etc., (Buhler). Body painting of one form or another was the main use of the yellow powder in Polynesia, and there are distinct sexual overtones to its use. On the Marquesas it was used in quantity by adolescents, particularly during orgiastic ceremonies and other situations involving sexual activity. The smell was supposed to have a sexually stimulating effect (Suggs). To the Muria, of India, the yellow colour makes it both a ghost scarer and a sexual symbol. The oil with which it is mixed is another sex symbol, recalling the oil traditionally put on a lover's mat to make it slippery (Elwin). The rubbing of turmeric and oil on the bride and groom is an essential part of a marriage festival in India (Pandey).
Achieve the safe and effective use of the drug. Pharmacogenetics and pharmacogenomics are the sciences of understanding the correlation between an individual patient's genetic makeup (genotype) and their response to drug treatment. They already have influenced therapeutics. For a drug that is primarily metabolized by CYP2D6, approximately 7 of Caucasians will not be able to metabolize the drug, but the percentage for other racial populations is generally far lower. Similar information is known for other pathways, prominently, CYP2C19 and -acetyl transferase. For example, codeine is metabolized to its active molecule, and about 10 of the population are rapid metabolizers and only need a much smaller dose for the same pharmacodynamic outcome. Omeprazole, used to treat peptic ulcers, is poorly metabolized related to SNPs in the CYP2C19 liver enzyme in 2.5-6 of Caucasians and 15-23 of Asians. For thiopurine, an antimetabolite used in cancer chemotherapy, the dose is 1 10 for the poor...
(Santalum album) A fragrant oil, called Oil of Santal, is distilled from the heartwood for use in perfumery and cosmetics. The paste that can be got by rubbing the wood on a stone with a little water is used for painting the body after bathing, and is also used for making caste marks, especially in south India (Pandey). The Chinese make joss sticks from the wood (Usher), and incense from the sawdust, mixed with swine's dung( ) (Moldenke & Moldenke). The oil is used for the treatment of urinary complaints and sexually transmitted diseases, and heartwood is sliced and used in Chinese medicine for abdominal and chest pains, i.e., angina (Geng Junying). In Indian mythology, it is described as surrounded by snakes, but it is a sacred tree, and the devotees of Vishnu apply a paste made from it on their foreheads. Hindu funeral pyres are made from it if the family is rich enough to afford such a luxury (Upadhyaya).
Specific History
Inappropriate self-treatment with topical 5-fluorouracil (5-Fu) obtained from relatives or prescribed by misguided practitioners can alter lesions or hide established malignancies without effectively removing them. Patients will also attempt to treat themselves with various cosmetics and patent medications, but soon discover that this is fruitless.
Genetic Engineering
Tool available to accomplish this in the past was to breed animals selected specifically for this purpose. This in turn required many generations of gradual change in order to produce significant changes in the animals and also limited manipulation of genes to those that could be introduced by normal reproduction. Since the late 1970s, however, the technology for inserting all manner of genes into an animal's genome, including radically foreign genes (for example, genes from human beings), has progressively developed in sophistication. This opens up a vast range of possibilities for manipulating animals' genetic makeup and thus their phenotypic traits. In 1989, the U.S. Patent Office announced that it had issued the first animal patent for a mouse (see MICE) that was genetically engineered to be highly susceptible to developing tumors, a trait rendering the animal extremely valuable for cancer research.
Nuclear Transfer
This procedure could be beneficial for women who are not able to produce their own viable eggs. In such a case, a donor egg would be obtained and the nucleus removed. Then the intended mother's nucleus, containing her DNA, would be implanted into the donor egg. The egg would then contain the intended mother's genetic material but would also contain the cytoplasm and other structures from the donor. Because the nucleus with DNA is what determines the baby's genetic makeup, the baby would be genetically linked to the intended mother and not to the donor.
Historical Views
What have stimulated and continue to drive the charge of speciesism are justifications of many avoidable, nonessential human activities. Instrumental use of other animals, sport hunting,* factory farming,* testing of cosmetics, biomedical experiments, roadside animal shows, and recreational animal parks involve intentional, but avoidable damage to other animals' interests.
Antivivisectionists tend to be abolitionists (those who demand the total end of animal experimentation, whether accomplished immediately or gradually), but they may also have more limited and practical goals, such as the ending of certain kinds of experiments deemed morally unacceptable (e.g., cosmetics testing on rabbits' eyes by the Draize test, burn experiments on animals, or pain* experiments performed without anesthesia or analgesia). In contrast, animal welfarists, though they oppose cruelty, generally accept the use of animals in research but campaign for their more humane treatment and for reduction, refinement, and replacement (the Three Rs see ALTERNATIVES TO ANIMAL EXPERIMENTS) in regard to overall animal usage.
Dowding Lady Muriel
Lady Muriel Dowding (1908-1981), a leading British humanitarian, vegetarian, and antivivisectionist, was the founder in 1959 and later chairperson of Beauty without Cruelty, the organization that led the way in the commercial production of synthetic alternatives to fur and cruelty-free cosmetics. She was a longtime president of the National Anti-Vivisection Society. In 1969, she cofounded the International Association against Painful Experiments on Animals (IAAPEA) and remained a patron until her death. She was the wife of Air-Chief Marshall the Lord Dowding, former commanderin-chief of the British Fighter Command, who died in 1970. Together, they shared a lifelong interest in spiritualism that informed their ethical concern for animals. Selected Bibliography. Berry, Rynn, Interview with Lady Dowding, in The New Vegetarians (New York Pythagorean Publishers, 1993), 137-152 Brophy, Brigid, The Darwinist's Dilemma, in David A. Paterson and Richard D. Ryder (Eds.), Animals' Rights A...
Red No
In 1990, FDA outlawed several uses of the strawberry-toned FD&C Red No. 3, invoking the Delaney Clause. The banned uses include cosmetics and externally applied drugs, as well as uses of the color's non-water-soluble form. FDA previously had allowed these provisional uses while studies were in progress to evaluate the color's safety. Research later showed large amounts of the color cause thyroid tumors in male rats. Though FDA viewed the cancer risk by Red No. 3 as low, ca. 1 in 100,000 over a 70-year lifetime, the agency banned provisional listings because of Delaney directives. At the same time, Red No. 3 has permanent listings for food and drug uses that are still allowed, although the agency has announced plans to propose revoking these uses as well. For now, Red No. 3 can be used in foods and oral medications. Products such as maraschino cherries, bubble gum, baked goods, and all sorts of snack foods and candy may contain Red No. 3.
(Anchusa officinalis) The gentlewomen of France do paint their faces with these roots. as it is said (Gerard). Anchusa is from the Greek meaning to paint or dye (another species is Dyer's Bugloss (A tinctoria). Alkanet seems to be one of the most ancient of face cosmetics (Clair). This use of the roots for making rouge led to the plant becoming known as a symbol of falsehood (Folkard).
Environmental stresses can cause changes in the genetic makeup of a population by favoring organisms with certain alleles more than others. This is, in fact, the normal way that populations can adapt rapidly to changes in their environment without mutations being required to produce new adaptations. It is also the reason why populations with genetic diversity are more likely to survive in the face of change. However, there is another side of this phenomenon related to human impacts on populations. Toxins added to the environment exert selection pressure for individuals that are more tolerant of the toxins. One negative impact of this is that it can reduce the genetic diversity of a population, making it vulnerable to further stresses. Another problem occurs if the organism is a pest and the toxicant is an agent such as a pesticide or antibiotic. As a result of the selection pressure, the population seems to develop tolerance or resistance to the agent, which then becomes less...
Sludge Treatment
Up until the past decade, all forms of these concentrated residuals, whether raw or treated, were commonly described with the same sludge label in deference to the typically negative context associated with words whose spelling begins with sl '' (e.g., slap, sleet, slum, slam, etc.). However, despite the unwholesome connotations implied by sludge, the nature and makeup of many properly treated residuals (i.e., suitably degraded, stabilized, disinfected, and dewatered) can actually be rather positive, if not altogether even valuable harkening back, as it were, to the earliest days of wastewater processing as a means of generating nutrient-rich fertilizers.
(Nardostachys jatamansi) This is the Spikenard of the Bible (Moldenke & Moldenke), the spike being the ear that grows from the rhizome (Dalby). It has scented roots, which are used in India as a perfume for the hair (Moldenke & Moldenke), and the oil is used to improve hair growth (Lewis & Elvin-Lewis). Distillation of this root produces oil of spikenard, although all parts contain the aromatic oil, especially the rootstock, whose fragrant oil is mixed with other oils to make spikenard ointment, once used in cosmetics and in medicine for the treatment of nervous disorders (Zohary). The 'ointment of spikenard' Mary used to anoint Jesus's feet before the last supper is thought to have been derived from this plant (Lewington), but there are other candidates, the desert Camel grass (Cymbopogon schoenanthus) being one.
Amino Acids
Amino acids are used extensively in the food industry as flavor enhancers, antioxidants, and nutritional supplements in agriculture, as feed additives in medicine, in infusion solutions for postoperative treatment and in the chemical industry, as starting materials for the manufacture of polymers and cosmetics (Glick and Pasternak, 1998). For the most part, amino acids are commercially produced either by extraction from protein hydrolysates or as fermentation products of either Corynebacterium or Brevibacterium spp., which are both nonsporulating Gram-positive soil bacteria (Glick and Pasternak, 1998). Traditionally, the productivity of these organisms has been improved by mutagenesis and subsequent screening for strains that overproduce certain amino acids (Glick and Pasternak, 1998 Demian, 2000b). However, this way of developing new strains is slow and sometimes inefficient.
Triclosan is a chlorinated bisphenol, which dissolves well in some detergents such as anionic soaps, and alcohol. It is only sparingly soluble in water. Concentration of 0.2 -2 are effective against gram-positive bacteria and gram-negative bacteria but with variable and poor activity against Pseudomonas aeruginosa. This agent is also active against mycobacteria and Candida spp., but it has limited activity against filamentous fungi such as Aspergillus spp. 49,72 . Because of acceptable antimicrobial activity, use of triclosan has risen dramatically in the past few years. Today it is used as an additive to hand soaps, dish-washing products, cosmetics, and toothpaste. It is also used as an additive to plastics, polymers, and textile and implant devices to confer these materials with antibacterial properties.
Although SPME has been widely used for highly efficient extraction of food components, little is known about the applicability of this technique for monitoring fragrance materials in household cleaning products, soaps, detergents, cosmetics, toiletries, etc. (61-63). Until recently, costly and laborious sample preparation techniques were required to isolate, separate, and identify fragrance components in perfumery matrices.
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This is the time of year when I like to set aside a chunk of time to be alone and do some introspection about what I want to happen in the upcoming year.
In fact, that's exactly what I did this past week. I hung out all alone in my office, journaling, planning and goal setting.
That's when I came across the 28 self-analysis questions from Napoleon Hill's classic book, Think and Grow Rich.
To be honest, it's been decades since I first read the book. I've picked it up several times since then, and still find it difficult to complete.
Yes, it's true.
I suppose that's why Sharon Lechter wrote Think and Grow Rich for Women. I do have to say, I'm so pleased with this version, written from a woman's perspective. (But I digress.)
I found Hill's questions to be a great journal prompt for reviewing the past year, and planning for what's to come.
Although, I do suggest answering the questions in segments in order to dive deep and not rush through the process.
Here are the 28 questions so you can dig deep into your New Year business planning, too. Enjoy!
SELF-ANALYSIS QUESTIONNAIRE FOR PERSONAL INVENTORY, by Napoleon Hill (1937).
- Have I attained the goal which I established as my objective for this year? (You should work with a definite yearly objective to be attained as a part of your major life objective).
- Have I delivered service of the best possible QUALITY of which I was capable, or could I have improved any part of this service?
- Have I delivered service in the greatest possible QUANTITY of which I was capable?
- Has the spirit of my conduct been harmonious and cooperative at all times?
- Have I permitted the habit of PRACRASTINATION to decrease my efficiency, and if so, to what extent?
- Have I improved my PERSONALITY, and if so, in what ways?
- Have I been PERSISTENT in following my plans through to completion?
- Have I reached DECISIONS PROMPTLY AND DEFINITELY on all occasions?
- Have I permitted any one or more of the six basic fears to decrease my efficiency?
- Have I been either "over-cautious," or "under-cautious?"
- Has my relationship with my associates in work been pleasant, or unpleasant? If it has been unpleasant, has the fault been partly or wholly mine?
- Have I dissipated any of my energy through lack of CONCENTRATION of effort?
- Have I been open minded and tolerant in connection with all subjects?
- In what way have I improved my ability to render service?
- Have I been intemperate in any of my habits?
- Have I expressed, either openly or secretly, any form of EGOTISM?
- Has my conduct toward my associates been such that it has induced them to RESPECT me?
- Have my opinions and DECISIONS been based upon guesswork, or accuracy of analysis and THOUGHT?
- Have I followed the habit of budgeting my time, my expenses, and my income, and have I been conservative in these budgets?
- How much time have I devoted to UNPROFITABLE effort which I might have used to better advantage?
- How may I RE-BUDGET my time, and change my habits so I will be more efficient during the coming year?
- Have I been guilty of any conduct which was not approved by my conscience?
- In what ways have I rendered MORE SERVICE AND BETTER SERVICE than I was paid to render?
- Have I been unfair to anyone, and if so, in what way?
- If I had been the purchaser of my own services for the year, would I be satisfied with my purchase?
- Am I in the right vocation, and if not, why not?
- Has the purchaser of my services been satisfied with the service I have rendered, and if not, why not?
- What is my present rating on the fundamental principles of success? (Make this rating fairly, and frankly, and have it checked by someone who is courageous enough to do it accurately).
As an award-winning spiritual life & money coach who is highly trained in the financial & insurance services industry, my focus is women, healing and financial empowerment. Currently, I'm fascinated by the mind-body-money connection because this is where you truly release the blocks and patterns that are holding you back from enjoying the financial success you truly desire.
My goal is to help you break free of the blocks and patterns that hold you back in any aspect of your financial journey. But, more importantly, I want you to be able to retire with enough money to take care of your needs throughout your golden years (when you can no longer work), no matter how long you may live.

subset: commoncrawl


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Missy is still having problems getting around. It's not so bad just walking...although I can see she is slower and hesitant. But she cannot jump up on anything...at least not easily. It appears she has not much strength in her hindquarters.
I went on to breakfast with Bob and when I got home I looked for her and she was up on the daybed. Strange...it is a lot taller then the recliner..even with me in it. Yet, somehow, she got up there. That is her favorite place nowadays.
In about ten minutes, I will leave for Independence. I will meet my daughter at the museum up there to look at Christmas crafts and decorations at three different locations. I probably won't buy anything. I didn't last year. But I like to look anyhow.
Bob is having some trouble with his hip again. he finally heard from his doctor that he has a deteriorating disk in his back and the nerve is extending out of it and being pinched. He has an appointment with Dr. Hsu to discuss the options on December 21st. Denise will go with him. I will be in Florida at that time. He had a bad day yesterday. For several days it had been a lot better and then he walked around our Walmart store yesterday afternoon and aggravated it and it hurt again last evening. This morning it appeared to be alright again. He just can't do a lot of walking or it starts hurting again.
It's time for me to leave so I'll get back to this later today when I get back home..
More later...
Got home just in time to leave for Independence to check out the Christmas Bazaars there. I met Leslie and we walked through five of them but neither of us bought anything. We neither one of us have room for anything else. But it was fun to look anyhow.
I got back home about 11:00.
More even later...
I called Bob and asked him if he was still interested in going to Joplin. he was. So I picked him up and we went over to Joplin. I wanted to go to Christmas shop. I only lack the little girls now and I am going to buy them books.
After the shopping,We went to Olive Garden to have soup and salad for lunch with raspberry tea. Everything was very good but they were swamped. We sat near a very noisy family who kept our waiter scurrying. We had a late lunch. We got out of Olive Garden at 3:00.
When I got Bob home to his apartment to take his nap, I went home and rested up too. He came over that evening and watched the news with me and when he went home, Missy and I watched TV until we went to bed. She is still crippling around. Her hindquarters seem to be the problem. They seem to have lost their strength.
Saturday, December 3, 2016
Saturday and Breakfast Out.
Posted by Margie's Musings at 8:25 AM
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Kendrie -- Day 215 Off-Treatment
Blaine -- almost back up to working full-days (I think he figures working is more restful than being at home with the kids during summer break)
The day after we returned from OKC, the kids were invited to a neighbor girl's birthday party. (Amy, if you're reading this, thanks again for the invitation!) Even though the party started at 4pm, when the temperature outside was reaching a million degrees Fahrenheit, and that's not counting the humidity or the heat index, I decided we would walk to the party since it was just around the corner, about eight houses away. I walked, Brayden rode her bike, and Kellen and Kendrie rode scooters.
We arrived at the party with the other guests, and merriment and frivolity began. There was pizza, and cake and ice cream, and silly string, and water balloons, and a prize box, and a piñata stuffed with candy. That was about the time Brayden made her enthusiastic observation, "Mom, this is the best party EVER!" (Too bad she didn't realize all the Laffy Taffy and Tootsie Rolls would be impounded by me the next day, after the Receiving of the Spacers Episode at the Orthodontists Office.)
I did have one sad moment during the party, when the kids lined up to whack the zebra piñata. In typical birthday fashion, the birthday girl of honor got to go first, then the rest of the kids lined up shortest to tallest. Kellen was the tallest, so the last in line. One of the kids before him had managed to knock off a zebra leg, but overall the thing was still pretty intact when he was ready to take his turn. As he squared up, like a big league hitter at the plate, broomstick at the ready, I admonished, "Kellen! Don't hit it hard --- the little kids might want another turn!" and the Mom of the party turned to me (Hi, again, Amy!) and said she wanted Kellen to hit it and burst it open, so the game could end. So, two good whacks, and candy went a-flying. The kids were scrambling, and happy, but I was feeling a bit nostalgic. Whatever happened to the good ole' days, when my short, young kids were in the front of the piñata line? And since when did my son become the big kid, delegated with the task of breaking the thing open? Today it's a piñata ….. tomorrow he'll be shaving, and driving, then marrying, and before you know it, he'll be applying for Social Security Benefits and carrying an AARP membership. OK, maybe I'm getting ahead of myself here, but it was a wee bit sad for me.
Anyway, on to the BESTEST PART EVER of the party ---- the party favors for guests? Goldfish! In their own bowls! With fish food and colored rocks for the bottom!!! I'm using a lot of exclamation points because that's how my own kids sounded as they were screaming for joy when they realized they would each get to take one home. (Of course, since we had walked to the party, and couldn't very well carry everything while riding bikes and scooters, in the zillion-degree weather, I had to call Blaine and get him to come pick us up. Half a block away. How sad is that? Nothing says, "Honey, I'm a lazy fat ass who needs lift --eight houses down-- because the goldfish are too heavy" quite like that does.)
So -- The next day? Petsmart! To buy water treatment tablets!! And castles!! Which were too tall for the bowls so they stick out the top!!!!
My kids are Ob. Sessed. They are pooling their money to buy a bigger tank, and more fish, and bigger, more grandiose castles. They've named their fish, and spend lots of time every day watching them, and studying them, and trying to convince me their fish look hungry and need to be fed again, and then squealing and giggling hysterically when they see one of them pooping in the bowl as is inevitable because they've been fed so much.
As for me, quite frankly, I can't take the pressure. It's bad enough that our dog is fifteen years old and every morning when we wake up I check to see if he's still breathing. Now my paranoia has extended itself to the damn fish. They're goldfish --- of course they're going to die! And my kids will be crushed. The best I can do is hope they all die at the same time, so one kid isn't more devastated than the other. In fact, I think I'll start setting my alarm so I get up before the kids. And then whenever the first fish dies, I'll take a teeny tiny pillow and suffocate the other fish. Then I'll blame the whole thing on a murder-suicide-goldfish pact.
If anyone has any better suggestions, I'm all ears. Just don't suggest I flush them, because we've got three tiny fish castles that the kids are determined to use. And big prospects for expansion. I don't know which is worse; to hope they die quickly and the obsession ends, or to hope they live, which means a bigger bowl and bigger castles might be in my future.
(sigh) Damn fish.
PS. Amy, you know I'm kidding --- the kids LOVE the fish!
PSS. Note to self: cross Amy off Christmas list.
Tuesday, July 18, 2006
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This is a discussion on Floofy Cattleya within the Photography Archive 1 forums, part of the Orchid Photography category; this is some obnoxiously long name hybrid I got from Maplethorpes for cheap. Flowers lasted ...
this is some obnoxiously long name hybrid I got from Maplethorpes for cheap. Flowers lasted about 3 weeks and were wonderfully fragrant.
Floofy for sure! What is the fragrance like? Though I don't go too much for the floof, the fragrance at shows I've been to is always impressive and so floral! Mmmm!
I cant say for sure what it smelled like, though it was a very floral type of a smell.
I love the smell of those. One I smelled at an orchid farm reminded me of my grandma's raspberry jam.


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Encrypt & Unlock Qtum Wallet
If you don't know how to deploy a Qtum node or don't know how to launch a Qtum wallet ,please refer to the following instructions:
- For command line users:《Guidance of Qtum Deployment》
- For GUI wallet users(common users):https://eco.qtum.org/wallet
Important: After you encrypt wallet or change your pin code, please remember to backup your wallet again!!!
Please do all following things after you successfully installed and run a Qtum wallet:
Encrypt Wallet
For command line users
qtum-cli command to encrypt wallet:
./qtum-cli encryptwallet "yourpassword"
note that
yourpasswordis the user defined password, please remember it or you might lost your QTUM.
After encryption, all fund security related actions (like send QTUM, staking, or dump private keys) will all requiring a password.
For GUI wallet users
Setting-Encrypt Wallet in the menu, as following:
create a new passphrase and repeat it. The wallet will restart after encryption.
After restart, there will be a lock flag shown on the bottom of the wallet, which means it is already encrypted (locked) :
Unlock wallet
For command line users
qtum-cli command to unlock wallet:
./qtum-cli walletpassphrase "yourpassword" 99999
the first argument
yourpassword is the passphrase you set when encryption, while the second is required unlock time, the unit is second (like 99999 seconds here).
After unlocking, you can send QTUM or do other fund security related actions.
If you only want to unlock the wallet for staking, please use :
./qtum-cli walletpassphrase "yourpassword" 99999 true
The first two arguments are the same, and the 3rd argument
true means you only want to unlock for staking. After doing this, you can start staking, but other fund security related actions like sending QTUM or dumping private key still need your passphrase to fully unlock your wallet first.
For GUI wallet users
Go to "Settings-unlock wallet" to unlock your wallet:
enter passphrase to unlock wallet. If you choose
For staking only, it means you only unlock the wallet for staking,but other fund security related actions like sending QTUM or dumping private key are still forbidened. So please unselect
For staking only if you want to fully unlock your wallet.
After unlocking, the lock flag on the bottom will switch to unlocked.
Change passphrase
For command line users
command for change passphrase:
./qtum-cli walletpassphrasechange "oldpassphrase" "newpassphrase"
oldpassphrase is the old passphrase you set last time,and
newpassphrase is the new passphrase you want set。
For GUI wallet users
Go to "Setting-Change Passphrase" to change passphrase:
enter old passphrase and new one to complete modification:


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Profession: English Teacher / Logistics co-ordinator / Football coach
Teaching Experience: Several years experience teaching people from around the world about pronunciation and grammar. I have also taught people about the logistics industry and helped others with shipping qualifications.
I have also been a football coach, teaching young ones about tactics and exercise.
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Health and Science
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Education: North Manchester academy / Manchester Openshaw College / ITS Training
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Episode 12!! And I hit 500 subs! And I made the Dev Report community spotlight! What a week! Well, I hope you all enjoy this video as it was a tough one to make, but you will see more in the video itself…….
Ciao for Now!
Intro/Outro Music:-
Suddenly – Otis McDonald
Music by Kevin MacLeod.
Available under the Creative Commons Attribution 3.0 Unported license.
Download link: https://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100414
Connect with me on:-
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This video was created using content of Bohemia Interactive a.s. and content created by Dean Hall
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See http://www.bistudio.com for more information.


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Background Search Premium WordPress Themes
When On the lookout for plugin or a theme, WordPress users are spoilt for choice. With the official repository, devoted marketplaces and various WordPress shops, there are thousands of options — so many, in reality, it can easily become hard to make a decision. Search Premium WordPress Themes
Making So is not something to be taken — the choice is vital to your site's success, however. After all, your site's theme will decide the design displayed to your customers, and your plugins will add most of its plugins.
To help You make an educated choice, I will take an in-depth look at one of the best places to purchase WordPress themes and plugins: MyThemeShop. As well as examining MyThemeShop in general, I will also be looking in its main features, reviewing a few of its best products and sharing hints for prospective buyers.
Click Here to register up to MyThemeShop Now!
Let's begin!
What Is MyThemeShop?
With a Title like MyThemeShop, you would think the answer would be clear cut. In fact, MyThemeShop occupies a middle ground somewhere between a WordPress theme shop and a WordPress'bar'. But because of its pricing policy, more leans towards being a club.
This is Because although all its products (MyThemeShop develops themes and plugins) are available to purchase individually, it also includes a membership option that provides users complete access to its whole product range.
Think It or not, MyThemeShop is one of the largest WordPress clubs round, boasting a catalog of 20 plugins and 99 topics and a satisfied clients. Search Premium WordPress Themes
MyThemeShop Support
As we have Touched numerous occasions in this article, MyThemeShop provides quality, 24/7 service for all its clients. And so that other users may learn from issues, it takes place primarily in its own support forum.
There is a Dedicated department for topics and plugins, also parting between free and superior products. Post your issue about the forum and among those MyThemeShop-employed service staff will respond to your query usually in no longer than an hour.
Instead Than only concentrating on paid members, MyThemeShop delivers great support to free users also, considering that the support someone receives for a product should not rely on whether they paid or not.
The forum Supports a search function, so that you may look to a problem — usually the fastest way to discover answers. Queries that were resolved are indicated with a postage.
Along with The service forum, MyThemeShop has included a collection of 45 video tutorials teaching the basics of WordPress, the way to utilize the MyThemeShop products, and even how to use some favorite non-MyThemeShop plugins. These videos are available via the Tutorial tab.
And, if You are still unable to fix your problem after posting to the support forum, MyThemeShop also provides support. In the event you require tweaks to your theme, specific customisations, website setup, or website migrations, the MyThemeShop service team can help you out (though these services are, as you'd expect, compensated ).
MyThemeShop WordPress Themes
Now, on Into the things that is important: its products' high quality and selection. We'll begin by studying MyThemeShop's core product range: WordPress themes.
The MyThemeShop collection is composed of 99 topics so far — 16 ones, and 83 premium topics. Search Premium WordPress Themes
MyThemeShop Topics were designed with usability in mind, and each theme ships with a market-leading motif options panel from which you are able to control the theme's settings, import dummy content (to have your site looking like the demo you saw when you purchased the motif ), or dive right into its numerous customisation options.
It is Worth taking a moment to discuss the extent of those customisation options, which makes the themes very versatile.
For a Start, every motif has support for infinite colours and the full catalogue of Google web fonts — over 600. Perhaps more importantly, all themes offer unlimited background options: such as a variety of built-in desktop layouts, the above unlimited colors, and also the choice to upload a custom background image.
The Themes are fairly feature-rich too. There is built in advertising management, fashionable and lightweight buttons, and contact type performance included with each motif. All topics come with support for the whole collection of MyThemeShop shortcodes, letting you incorporate eye-catching design elements to your website easily.
Most Importantly, though, is that under all of this is a lightweight, and powerful code. What's more, to make sure your website is as visitor-friendly as you possibly can, all themes boast a completely mobile responsive layout, lightning-quick load times, and cross-browser compatibility.
Another Bonus: every theme has a narrated movie tutorial, also MyThemeShop offers round-the-clock support that will help you out of any tight spots you may experience (more about this later).
The Topics are divided across four classes:
- Magazine topics (39 available)
- Website themes (41 available)
- WooCommerce topics (17 available)
- Business topics (9 available)
Searching For a motif is easy, and the MyThemeShop site has lots of features to give you a hand. For a start, you can look for themes in each of the four categories we have just listed, and there's another category for free and miscellaneous themes. Or, if you would prefer, you can start by searching for a keyword. Search Premium WordPress Themes
All Themes include a preview to help you to get an idea of the plan. These previews come in rows of three by default, butif you would prefer a slightly bigger preview, you can pick rows of two. There is also a filter that lets you sort the topics by release date or popularity.
Maybe Most useful of all is that MyThemeShop lets you choose which features you need in your theme. Features are chosen from a drop-down listing, and any theme that fails to meet with your standards is dropped out of the research page. There are nine options (and also you can pick more than one):
- Two column
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- AdSense optimised
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When You have discovered a theme you like the appearance of, you can click through to the theme's product page. Here, you'll have the ability to read more about this theme's major features, and you will get an notion of this theme's popularity — each theme involves a neighborhood rating from five.
As you'd Expect from one of the theme sellers every motif comes with its own demonstration.
Before You purchase a theme, I'd strongly recommend spending a couple of minutes. You will be able to sample the theme's layouts, try out the different customisation choices, and get an overall idea of how the motif looks and performs.
Click Here to sign up to MyThemeShop Now!
Most Popular MyThemeShop Topics
To give You a flavor of the characteristic of the topics, let's take a little time to check at a few of the best it has to offer you. No sales figures have been made available, so we're expecting the'popularity' search function . (Note: Click on a screenshot to be taken directly to the theme's demo page.)
From Social media to the search engines, Schema is a website tailored to dominating the SERPs — achieved by a carefully constructed, SEO-optimized design. The subject is also lightning fast, with website speed an important position factor. The site employs a stylish-yet-simple layout, plus it comes packaged with review performance and advertising management. For an SEO-focused motif named Schema, the theme, of course, adds the necessary Schema markup which powers Google wealthy snippets.
Social Traffic is always growing, and entire websites have popped up feeding exclusively off social traffic. If you are looking to construct a viral societal site, SociallyViral was built for you — the motif boasts many different features to Boost social shares and cater to viral traffic. That usually means a site with a great deal of social buttons, trending article widgets, and also, with one eye on monetization, advanced AdSense optimization.
Best is a beautiful, simple, and clean WordPress magazine theme. Even though Many magazine topics end up looking overly cluttered, Best remains organized throughout — it is clearly defined sections make your site easy for visitors to browse. As you'd expect from a magazine theme, there is also plenty of dedicated widgets; vivid, colorful social sharing buttons; and built-in review performance. Search Premium WordPress Themes
OnePage supports a gorgeous slider above The fold, catching traffic' attentions. It is primarily a company theme, supporting dedicated staff, portfolio, client, testimonials, and pricing segments — all of which seem extremely professional and extend stylish parallax effects. The motif also looks great when kitted out in its own alternative blogging skin.
PointPro is another stylish, professional motif, this Time in three variants — eCommerce shop, site, and business. The business template is particularly eye-catching, with a tidy, organized layout complementing a great deal of images — there is a picture slider, thumbnails, and gallery performance, also. The motif provides you loads of flexibility, with custom sidebars, boundless colors, and unlimited wallpapers.
MyThemeShop Plugins
As well As topics, MyThemeShop additionally has 20 WordPress plugins, including 12 premium (at $29 each) and eight complimentary.
All these Plugins permit you to add very special functionality to your site, such as telling bars, time-to-read quotes and coming soon pages.
You can Look for plugins in the exact same manner as topics, but, because plugins vary in terms of their capabilities, the plugin pages are the areas.
Each Plugin has a very long list of the plugin's features, giving you a very clear indicator of what it can (or can not ) do. You'll also see a user evaluation there's a presentation for every plugin so that you can see every one in action.
Most Popular MyThemeShop Plugins
Since There are fewer plugins than themes, let's run down the three MyThemeShop WordPress plugins. I provide a brief summary of what each plugin can perform.
WP Mega Menus provides amazing, interactive menus into your website. The menus arrive packed with options, and allow you to add thumbnail images. These menus are a prominent and stunning design feature for your site, plus they make it more straightforward to navigate.
WP Subscribe Pro lets you exhibit stylish popups and Subscription boxes to cultivate your list. This plugin boasts plenty of design choices to play , and support for exit intent technology. You could also integrate WP Subscribe Pro such as MailChimp AWeber and, of course, with the email marketing autoresponder solutions.
As the Name implies, WP Review Guru adds review functionality to any WordPress website. This lets you speed goods in style, utilizing a range of evaluation systems and customisation options. The plugin also adds your review posts, which powers the wealthy snippets of Google functionality and the schema markup. (Note: Recently featured in our best inspection plugin roundup.) Search Premium WordPress Themes
MyThemeShop Plans
With so Many competitors, how can MyThemeShop's theme and plugin prices pile up? Let us look at the product prices.
MyThemeShop Functions a pricing structure that is flat — any theme will put you back a 59, with plugins coming in at $29 each. This is a standard price for themes and plugins, and on a par with marketplaces such as ThemeForest and CodeCanyon.
If you Need access to its subject club, an membership account prices $167 a year. You'll receive access to client support and 20 plugins, as well as all 99 themes and access.
Membership Is more expensive than that of some of the other theme clubs, like ElegantThemes (from $59 a year), TeslaThemes (from $59 annually ), and ThemeIsle (from $99 a year), but more reasonably priced than the likes of WooThemes (from $399 a year — upgrade — 16th July: WooThemes.com is currently under the umbrella of WooCommerce.com, using their themes offered at https://woocommerce.com/product-category/themes/), WPMU Dev (from $294 annually ), also StudioPress (from $499 annually ).
Something Working well in its favour, though, is the simple fact that membership licences permit the goods to be used on an unlimited number of websites — which makes them ideal for agencies and salespeople. And, by purchasing the licence, as stated you receive continuing support. (Note: We'll get into this later on in the report.)
What is More, an elongated membership will also provide you with access to any new products published by MyThemeShop for the length of your subscription.
MyThemeShop Does a good job of releasing products that are new every few weeks — in 2015 with more than 30 releases.
In General, MyThemeShop is almost certainly among the WordPress clubs it delivers an impressive assortment. Throw in an excellent choice of plugins and service that is continuing, and it is not hard to see why more than 300,000 customers have taken the plunge and become MyThemeShop clients.
You will Be wondering if you should purchase motifs in an individual basis, or as a job lot as part of their'bar' subscription. This depends.
Should you Construct a lot of sites — perhaps as a programmer or a creative service the club membership is sure to be the most appealing alternative. This package will provide you access to almost a hundred themes to impress your customers each one comes loaded with customisation options so it is possible to tailor a site to a customer's liking.
If, However, you're an individual building a site that is single, the decision is difficult. On one hand, you'll save money by buying a single motif; on the other, paying for a club membership permits you to test your website until you discover the perfect one. Search Premium WordPress Themes
The Membership reflects the best value, and more than holds its own when compared for 20 specialist plugins and 99 quality topics is a complete bargain!
Click Here to register up to MyThemeShop Now!


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I stumbled across a website called NetGalley early last month, which allows Publishers to send books to the media and bloggers/influencers before they are released for free in return for a review. I was lucky enough to get the opportunity to read The Toymakers by Robert Dinsdale before general release and I fell in love… Continue reading The Toymakers
Tag: reading
My Reading List
One of my goals for this year is to read more books during my free time. During Uni, I didn't get the chance to read books for fun a lot of the time and I've missed it a lot! I decided to write a little list of the books I have lined up to read… Continue reading My Reading List
Happy New Year! Hope everyone had a great festive season. I've been a bit MIA for the last month due to a couple of things, but I'm going to try and keep this blog up as a goal for 2018. I'm not a big New Years Resolution type person, but this will be my first… Continue reading 2018