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TweetSquat Form Tips...
By: Rickey Dale Crain, B.B.A., I.S.S.A., IPF/WPC/AAU World Champion, 2000 Powerlifting Hall of Fame Inductee
Form, style and technique are everything.
Only in the world of powerlifting, when one is asked how to improve one's lifts, are we encouraged to try this new routine, or asked, "What is your routine? If I was a baseball player, I might ask what technique do you use to swing the bat, increase bat speed or shorten the distance the bat travels? I would not ask what routine you use to become a better hitter. If I was a football player, I might ask what technique should I use to throw the ball more accurate or faster/harder? Surely I would not ask what routine would I use to accomplish it. If I was a shot-putter, I would surely ask what form and style do you use to throw the shot 50-60 foot or more, not what routine did you use to accomplish the feat. So why in powerlifting is the first thing asked and the first thing offered is a routine? We dont ask how do we accomplish the lift the best way possible. The strongest do not always win. Instead, the best prepared and the ones who perform the lifts flawlessly are the ones who win. It is a goal orientated and a performance orientated sport like all others, so form, style and technique should be the first thing on the athletes mind, as well as the first thing on his agenda when trying to improve his lifts, i.e. his max single. I believe the reason we do not focus on form is that we have been influenced by our brother sport, bodybuilding, and its results orientated status. It has a big influence because of its popularity in magazines and books aimed at bodybuilders. It is, however, a different sport and has different goals and needs. We should not confuse the two, and allow it to get in the way of our goal as a powerlifter. Our goal is to become not only stronger, but in how to display that strength in the most productive way, i.e. a big single max lift. As we look into this phenomenon, let us describe what we are trying to accomplish. To describe this phenomenon, we need to understand some very simple terminology. Therefore, we shall agree on the following definitions: Form: The shape or appearance of a thing that makes it identifiable, and/or the nature, structure, or essence of a thing, considered apart from its content, color, texture, or composition. It is visible, distinct, or discernible. Style: A way of doing something; especially a way regarded as expressing a particular attitude or typifying a particular period (i.e. old style/school). A self-confident willingness in exhibiting skill or quality. Technique: The procedure, skill, or art used in a particular task. The way in which the basics of something are done. Skill or expertise in handling the technique of something. Special ability or knack. All three are separate and distinct, but all come into play and overlap in any sport when trying to achieve that maximum result. There are many areas of each lift: the squat, the bench press and the deadlift, that are effected by form, style and techniques.
Feet: in, out, straight, flat, raised Hips: going back, staying where they are, raised Hands: in, out, open, closed, palmed, on the bar, on the plates, on the collar, tilted in, out, straight Head: up, down, straight Arms: down, up, tilted in, out Breathing: how much you breathe, when you breathe
These all affect each other and in turn make up your form, style and technique, in conjunction with your body type and style and the length of your limbs, etc. These are just some of what is needed to be looked at to insure the best outcome of the lift. Your stroke (distance traveled) on the lifts, you can alter the distance traveled dramatically on the bench press and deadlift, but not so dramatically on the squat as to effect the increased or decreased leverage. So, as we begin to look at these always keep in mind: form, style and technique is everything. The squat and bench press seems to be more brute strength, but to excel at the deadlift, I always had to learn to finesse it up. I know for a fact that when lifting, through all the hundreds of state, regional, national, and world records I broke I was not the strongest on the platform. Instead, I was the smartest, the best prepared, and had the best form, style and technique.
Powerlifting became an official sport in 1963, thanks to Bob Hoffman and York barbell. The three powerlifts: the squat, the bench press, the deadlift are a true measure of strength and power. All are used, with success to train for almost all other sports in the world. When that contest time rolls around, however, the one who is the strongest does not always necessarily win. Rather, it is the one who displays the best combination of strength and power and is able to produce the big numbers coupled with form, style and technique. As in any sport these components are important and will usually be the difference in winning and losing. Better form not only yields more weight lifted, but also lessens the chance of injury and down time in training. Staying free of injury is as important as anything else, as longevity in this sport is determined by your health. The longer into your training career you go, the higher the numbers will be.
Let us look at each individual lift and break down all the parts that will affect what weight is lifted successfully, and how to perform them to your best advantage.
The Squat, the King of all lifts: Everybody's body structure can and does dictate different form and style, but some things are the same or very similar (or should be to be successful) for the vast majority of lifters. Let us take a look at these: -Hand placement on the bar and bar placement on the back -Arms and elbows -Walk out and set up -Feet placement and hips -Head placement and eyes -Breathing and flexing of certain muscles -Thinking and concentrating through the lift from beginning to end Before you approach the bar, all your equipment should be fitted and fitting properly. All your psyching up and mental preparation should be pretty much done. It is time to perform. Hand placement on the bar and bar placement on the back:
A persons structure, limb lengths and size have a lot to do with hand placement on the bar. The main rule of thumb is the closer the better. It will keep the bar tighter on your back, and no chance for the bar to roll. The lighter lifter usually has no problem with this, but the bigger and heavier lifter, usually through inflexibility, wants put his hands out wide. Thus, he decreases his leverage by the fact the bar will have to be placed higher on the neck to keep it from falling. "I will say this once, and I am sure I will take some hits on it, but it is the absolute truth. The vast majority of bigger/heavier lifters have very poor form, for many reasons, but inflexibility and the refusal to practice good form is the main reason. They pretty much try to rely on their size to muscle up a lot of weight. That is one reason why the smaller lifter is so much superior pound for pound at all the lifts."
The weight should be supported by not only the back of the deltoids where the bar sits, but some should be supported by the arms, forearms, elbows, wrists, hands. This dictates as narrow a hand placement as possible. Smaller frame people will have narrower grips than bigger frame people, i.e. my grip is considerably narrower than Bill Kazmaier's. Grip the bar tight. The tighter the grip, the less pressure will be on the wrists and elbows and shoulders, and the bar will have less of a chance or almost no chance of moving or rolling. Arms and elbows:
If your elbows, wrists or shoulders hurt, try tilting your elbows up as you get under the bar, and/or rotate your hands a bit inward. If you still have a lot of problems, you may need to move the grip out a bit, but work on flexibility constantly so as to keep them in as close as possible. The wider the grip the more the hands will probably tilt inward. I disagree with false grips. They are dangerous because you do not have the bar under full control, and it makes you place the bar higher on the neck, hurting your leverage. Also, some federations allow holding the collars. This practice is very dangerous and really cuts down the leverage. The key is to not only feel tight but also be tight and have everything under control. The lower the bar, the better your leverage is and the more the hips will be utilized. And the hips are where the power comes from. You should not squat totally upright utilizing the legs only.
Only a few people are so big they cannot grip the bar fully and squeeze into a position inside the collars. Many big guys could work on flexibility and be able to achieve this. Walk out and set up:
Walk under the bar, elbows high, squeezing the bar tight and pull yourself under the bar. With the bar about 1-2 inches or so below the deltoid or shoulder, there is a groove for every person that will be evident and sit comfortably. You may have to experiment to find it or it may come naturally. If you are having trouble finding it, ask an experienced lifter. After the bar is sitting tight on your back, set your feet side by side but with one foot just ahead of the other, i.e. heel to toe. Make sure your back is chalked up good to help keep the bar from slipping down your back.
Take a very deep breath, squeeze your hands, shoulders, abs, (i.e. everything) and swing the hips forward. Push up and come back out of the rack. The momentum of the bar and plates, while under control will help you to come out of the rack much easier. Walk out with a minimum of steps, 2-3 at the most. Practice your walk out with an empty bar and while warming up. Practice does make perfect, and learn to do it right every time.
Feet placement and hips:
After walking out and setting up, make sure your feet are the proper distance apart. What is that you might ask? Hopefully you have some idea what is comfortable, and best suited to your body structure, age and strengths. In case you have not a clue as to what planet we are now on, here a few helpful suggestions: -Shorter people usually are narrower -Taller people further apart -Short back and long legged people (i.e. Lamar Gant) can use either form of foot placement Look at this chart to summarize stances:
Short Back Medium Back Long Backs
Short Legs: Med/Wide Medium/Wide Short/Medium
Medium Legs: Med/Wide Med/Wide Short/Medium
Long Legs: Narrow/Med/Wide Medium Short/Medium
This is fairly accurate and there are reasons for the above. It would take a few pages and 20 minutes to put it down on paper to give it a fair discussion. If you really want to know call or e-mail and we will talk. Hip, leg, and back strength also dictate to a point where your stance might be at the present...but not where it should be. See the chart below to help with this area:
Strength comes from: Hips Legs Back
Stance: Wide Wide/Med Med/Narrow
Head placement and eyes:
After walking out and setting up, look out (not up too far), but never down! Now your head can be in 1 of 4 places:
1. Looking way up - for people with wider stances, and the bar higher on their back (and checking out for aliens and space ships in the sky).
2. Looking out - for the average lifter, and the most correct way.
3. Looking down - for the closer stance squatter with the bar really low on the back (and also allows you to check to see if you tied your shoes).
4. Looking at the mat, with a flat face, showing you screwed up and haven't listened to anything I've said to you.
Breathing and flexing of certain muscles:
You should still be holding that deep breath from the set up and walk out. Make sure as you get ready to descend (that means go down for some of you), you are flexing everything: abs, face, hands, neck, and all upper body parts. As you go down, push your knees out, hard. As you cock your hips and shoot them back (as if sitting on a chair), get your chest out, shoulders back, and have a small arch in the back. At the bottom, your shins should be vertical or almost vertical and never past your feet. Michael Bridges made this popular by giving it a name: The Bridges Fair. It has been part of my form, however, for 30 plus years. As you approach the bottom of the lift, where the imaginary line from the top of the knee to your hip joint breaks parallel, you pull yourself through the point with a slight bounce. Then drive upward with your upper body, hands, arms, legs, hips, back, or otherwise with everything you own. Sometimes the imaginary line is more imaginary at times than others depending on how much you paid the referee or whether you are dating his sister or daughter. As you stand up (or get scraped up, whatever the case may be) and as you complete the lift, go ahead and walk forward and rack the bar. Hopefully the spotter/loaders are not taking a lunch break and will help you a bit, hopefully a lot. Stop, walk, rack, and breathe. Finally it is over. Thinking and concentrating through the lift from beginning to end:
Remember: Squat slow and under control. Form is everything. Always squeeze the bar. Always squeeze your abs (or ab, whatever the case may be). Always squeeze everything. Practice makes almost always perfect. And remember, form and style is in essence more important than the workout itself. Age dictates style and form. The older you get, the more your form will need to be altered or adjusted. Sex (male or female, not the action) will dictate form changes. Experience in lifting, etc. will also be a factor.
sumo set up.......... approach the bar...........take one foot or the other....your choice as to which is most comfortable and depending on whether you are a wide sumo or a narrow sumo..............the shin goes up to the bar.....toes tilted out 45 degrees or even more in some cases...........shins vertical...knees slightly bent........hands down inside the legs with the forearms touching the inside of the thigh if possible..........as you push your knees out (like the squat)......you bend over slightly....arms straight....and grasp the bar half on and half off the knurling..........arms should be straight vertically from the shoulders to the bar..this will determine exactly where the hands are to be placed.........for a very big lifter with wider shoulders this may be all the way on the knurling......but for most; half off and half on will insure the best and shortest pull...........THE ARMS ARE STRAIGHT........AND THE BAR LIES IN THE FINGERS, LIKE IT IS HOLDING A HOOK......THUMB OVERLAPPING ONE OR TWO OF THE FIRST TWO FINGERS.......the bar should "not" be squeezed......it should just lay in the fingers/hand..only the thumb should be flexed....or squeezed......not the hands...not the forearm.......if this is done incorrectly most likely the bar on a very hard pull will slip out of the hands.........also if the hands are rotated as you grip the bar..it will most likely slip out as the weight pulls down and pulls the rotated hands back to a straight up and down position......one does not have to have a strong grip to hold onto large amounts of weight.......i have a very poor grip and grip strength and have never lost a deadlift......i.e 716 at 165lbs......... as you are leaning over the bar knees pushed out.....you dip the hips slightly to start your pull......short and sweet.........the hips will pull in towards the bar......the head will follow from down to out as you start the pull.....you will pull the slack first out from the plate/bar...then the bend in the bar slack will come next............the bar will pull into the fingers even more as this slack is pulled out and as all the different areas of slack are pulled out you will explode.......up.......with a very short in line stroke............the back will not be arched but have a slight curve in it/or perhaps even straight.........you should take a short half breath right as you go down to the bar..........too much breath expands the chest and rib cagemore than it need be........raises the shoulders and lengthens the distance the bar travels...as well as forces the shoulders back while at the bottom......right before the pull......... a variation of the slow sumo pull is the drop and grab and explode method......everything is still the same as far as the hands.........but it is done very quickly........many times, when done to quickly or out of control, one grabs the bar wrong and/or the hips rise to fast...giving way to a stiff legged deadlift...... conventional stance......... walk to the bar.....feet about shoulder width.......the shins should be 2-4 inches from it........some minute experimentation will find the exact spot you need to be........as you lean over to the bar...grab it the same way as you did in the sumo except outside the legs a few inches on the knurling........touching the calves....small breath and dip the hips and pull........one variation of this used, nowdays is to dip...roll the bar a few inches out in front of you and then reverse and pull it back in;...as it gets to the shins start the pull upward......some momentum can be obtained from this and the bar can be started in closer to the center of gravity...but if not done exactly right a moving bar can be a problem..... form...style....and technique......is more important than the routine.......we know this to be true in every sport and so it is in powerlifitng.........we need to concentrate more on it...and spend hours on it...consistently........every week........throughout your whole career.............a baseball player takes thousands of swings.....a week........so a lifter should do many...many reps with little or no weight to perfect his form....style and technique.......
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Hot off the Press
Salvagnini to Open Canadian Showroom
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Monday, January 6, 2014
Sheetmetal-fabricating machinery supplier Salvagnini, Hamilton, OH, announced plans to open a full-service office, spare-parts warehouse and showroom in Ontario, Canada, in May 2014. Salvagnini Canada, ULC will continue to operate from temporary facilities in Mississauga, Ontario, until the new facility opens. It will staff the office with a regional sales manager, office manager and three field-service engineers. More at www.salvagnini.com/.
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subset: commoncrawl


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Sun, Oct 08
31 HORROR STORIES – "Men Without Bones" (1954)@ 12:00 PM
Gerald Kersh is another one of those writers who have so many good stories -- and such great titles! -- but the problem with Kersh would be choosing his SECOND best story. "The Dancing Doll", "The Man Who Sold His Head", "A Game Played in the Twilight", and "The Unkillable Man" would all be up there.
But Kersh took a trip into the metaphoric jungle, as well as outside the margins of space and time, for this one. If you're a fan of British gangster films, and are as aware of how influental Kersh's work was on the genre, then this story will confuse and chill you.
An explorer is dying, and tells a fellow passenger on his boat about discovering a crashed alien spaceship deep in the darkest jungle. And then, before he dies, he lets slip the even WORSE thing he discovered.
I know everyone likes "Sweets for the Sweet" and "To Serve Man" for their punch-in-the-gut, final line, twist endings.
But I think this one's got 'em beat.


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ANSI/TIA-1179 "Healthcare Facility Telecommunications Infrastructure" was developed by the TIA TR-42.1 Commercial Building Cabling Subcommittee and published in July, 2010. This Standard specifies recognized cabling and cabling category recommendations for healthcare facilities. In addition to IT systems, the structured cabling specified by this Standard is also intended to support a wide range of clinical and non-clinical systems such as non-IP and IP-based RFID, BAS, nurse call, security, access control, and pharmaceutical inventory.
This Standard provides specifications for the planning and installation of a structured cabling system for healthcare facilities and buildings. Included are requirements for cabling, cabling topologies, and cabling distances, pathways and spaces (e.g., sizing and location), and other ancillary requirements. Guidance on selection of media and network design is provided and of particular importance for larger healthcare facilities, which may have a useful life far longer than traditional office-oriented commercial buildings.
NOTE: TIA-1179 under revision
In 2010 the Telecommunications Industry Association (TIA) published the ANSI/TIA-1179 Healthcare Infrastructure Standard. The standard was the culmination of years of work within the TIA's TR-42 Engineering Committee that began in 2004 when a study group was formed in an attempt to gain an understanding of the telecommunications and connectivity needs of healthcare environments. The study group's findings prompted the formation of a task group, whose responsibility was to define those needs in the form of a standard.
The ultimate product-ANSI/TIA-1179-is based on the ANSI/TIA-568 series of standards, which specify generic telecommunications cabling for customer premises. That is to say, the 1179 standard does not rehash or deviate from the fundamentals spelled out in 568, but rather, 1179 builds upon them with requirements and recommendations specific to healthcare environments. A notable difference between the 1179 and 568 standards is that within TIA-1179, the size of the telecommunications room is increased to a 130-square-foot minimum, to allow for as much as 100-percent growth. Also, the 1179 standard takes an entirely different approach to work-area cabling and in particular the volume of connections needed within a work area. In a commercial office building, a work area may be a desk, conference room, or other shared-use space. In a healthcare facility, a work area may be anything from a waiting room to a nurses' station or a patient room. Accordingly, the 1179 standard specifies low, medium, and high densities for work-area outlet volume and includes examples of the types of spaces to which each density may apply. TIA-1179 recommends 2 to 6 work area outlets (WAOs) for low-density areas, 6 to 14 WAOs for medium-density areas, and more than 14 WAOs for high-density areas. The standard also recognizes certain twisted-pair copper, multimode fiber, and singlemode fiber media types for use in backbone and horizontal cabling circuits, as well as recommending specific performance levels.
Per ANSI (American National Standards Institute) procedures, in 2015-five years after publication of TIA-1179-work began on a revision to the standard, which will be published as ANSI/TIA-1179-A. During an online seminar hosted by Cabling Installation & Maintenance and originally broadcast on November 10, Henry Franc-national solutions specialist with Belden and chair of the TIA's TR-42.1 subcommittee that is revising the standard-delivered a presentation updating the status of the revision project.
Within that presentation Franc explained that the revised standard is currently in a fourth draft. Like the original, TIA-1179-A will be based on the TIA's 568 standard set. Because the 568 standard set has been updated since the original publication of 1179, the 1179-A standard will be based on the most-recent iteration, which is ANSI/TIA-568.1-D. Additionally, the "A" revision will include references to other TIA documents, including the following.
ANSI/TIA-862-B Structured Cabling Infrastructure Standard for Intelligent Building Systems
ANSI/TIA-5017 Telecommunications Physical Network Security Standard
ANSI/TIA-606-B Administration Standard for Telecommunications Infrastructure
ANSI/TIA-607-C Generic Telecommunications Bonding and Grounding (Earthing) for Customer Premises
ANSI/TIA-942-A Telecommunications Infrastructure Standard for Data Centers
ANSI/TIA-1005-A Telecommunications Infrastructure Standard for Industrial Premises
Telecommunications Systems Bulletin TSB-162-A Telecommunications Cabling Guidelines for Wireless Access Points
Telecommunications Systems Bulletin TSB-5018 Structured Cabling Infrastructure Guidelines To Support Distributed Antenna Systems
Franc further noted that, as of its current draft, the 1179-A standard includes multiple-user telecommunications outlet assemblies (MUTOAs) and consolidation points as design elements for structured cabling systems in healthcare environments. The standard includes additional requirements for systems such as wireless access points, distributed antenna systems, security systems, intelligent building systems and others. When speaking about intelligent building systems, he pointed out that systems such as nurse-call and wayfinding fall within this framework.
Additionally, Draft 4 of the standard permits array (MPO-style) fiber connectors in the work area and it requires a minimum of two fibers in backbone and horizontal links.
The committee drafting the revision has not come to consensus on recommendations for media performance levels.


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My name is Paul. I've been a BMWMOA member since I bought my first beemer in 1978; an R80/7. Since then I've owned a R100RT and now a R1100RT. I'm a long distance solo rider. Solo in that I don't tend to join clubs a do group rides. I like the freedom of deciding where I want to go without having to negotiate. I'm not adverse to riding with others I just don't really know too many other riders in the area.
I live in RI and VA because my job is in DC. I commute to work on the beemer year round and do a lot of weekend riding around the VA, WV back roads. I'm leaving July 1 for a 16 day trip that will end up totaling about 6,200. Counting the days.
"Keep the rubber side down"


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The Accounting Historians Journal Vol. 16, No. 2 December 1989
Sarah Auman Reed TEXAS A&M UNIVERSITY
Abstract: This paper examines the magnitude of the reporting bias inherent in the historical cost accounting of a firm's physical capital. Reported depreciation data pertaining to U.S. Steel Corpo-ration (currently USX) between 1939 and 1987 are compared with standardized historical cost figures and replacement cost esti-mates. The findings suggest that replacement cost depreciation would have provided more information about U.S. Steel's ability to maintain its productive capacity than historical cost depreciation did. Thus, this analysis provides an illustration of one of the primary arguments for replacement cost accounting.
Changing prices have created accounting measurement problems for business enterprises throughout the twentieth century. Paton [1922] noted that in periods of sweeping price changes the accountants' yardstick (money) becomes "an un-stable, variable unit; and comparisons of unadjusted accounting statements prepared at intervals are accordingly always more or less unsatisfactory and are often positively misleading . . . When prices on all sides are climbing sharply it seems clear that a mere increase in the number of dollars possessed is not a valid expression of true improvement in economic condition" [pp. 427-428]. In such periods, Paton pointed out that management must be careful not to pursue a dividend policy which threatens "the preservation and expansion of the physical capital of the enterprise" [p. 440].
Paton argued that "by reducing what would otherwise be the net income figure," recognition of replacement cost depre-
I would like to thank Barbara Merino for her helpful comments on earlier drafts of this paper and for her professional guidance in general. This paper also has benefitted from the substantive comments provided by four anonymous reviewers. Finally, I would like to thank graduate students: Byron Harris, William Shows, and Alan Pavelec.


text: By Dr. Cathy Alinovi, D.V.M. One of the worst experiences for pet owners is to watch their dog or cat have a seizure. Canine seizures can range from mild ones that look like your dog was bitten by a bug, moderate muscle tremors and drooling, to full-blown laying on the side, screaming, arching the back,


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In this tutorial the Guru shows you how to make lush pads from just about any monophonic melody using Edison and Newtone (or just Edison if you don't have Newtone) ...
Download the project created above here
The steps are:
1. Load a monophonic melody (vocal/instrumental whatever you have, tonal/timbre variation is good) into Newtone. If you don't have Newtone you can get it here. You can also skip this step and use Edison edit out a string of notes of the same pitch.
2. Use Newtone to flatten the pitch to a single note (close to the average of the melody).
3. Load the flattened melody into Edison and remove any gaps between notes and other non-melodic noises. 'S,T,C,CH & F' sounds can become unwanted noise 'hiss' after blurring.
4. Add at least 4 seconds silence before and after the flattened melody.
5. NOTE: If your sample is mono, convert it to stereo before blurring it.
6. Apply the Blur tool function with ~4000 ms 'Amount' setting
7. Load the Blurred sample into your favourite sampler. Don't forget to set the root-note to the correct pitch of the sound.


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On this rudimentary website shall be posted the collected segments that ran on the Cavalier Daily's comics page under the title Amazing But True. While having a website to post my strips is a bonus, the real boon is my ownership of "Amazing Butt Rue UVa dot com."
Read Amazing... But True!! in the Cavalier Daily 3 times a week!
NEW: I'm taking question submissions for my "Mailbag" segment. Send your UVa queries to: abtuva (splat) gmail (dort) com. Hopefully you can figure that out if you aren't a robot designed to send me spam.
Like This on Facebook
"Wahoo"posted Jan 24, 2010, 11:54 AM by James Maxwell


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Jackson Rathbone & the Twilight makeup artist
Even Twi-Hards will agree: the wig and makeup situation in the Twilight movies is f-cking busted. This is supposed to be the most ridiculously beautiful family maybe ever, and instead when Jasper comes on the screen looking like a crazed clown, the laughs far outnumber the moists. Which is almost criminal. Because non-Twilight Jackson Rathbone is normally SO hot.
But for some reason he allowed Twilight's makeup artist to do his face for the Kids' Choice Awards. And the result is this.
I get it that he doesn't want to style it like Zac Efron, too bronzed and glossy, but Jackson Rathbone is supposed to be the one among them who doesn't give a sh-t. Unlike that beefcheese Kellan Lutz and his tree posing, or Taylor Lautner and his side leans, or contrived Pattinson and his open mouth, Jackson kinda lets it fly. Fine. Great. So wear nothing. Why wear white powder and a red mouth? If it's a statement I'd rather he not make one at all.
Jackson was at the event on double duty. He of course is one of the stars of the Twilight Saga and Eclipse opens at the end of June, but he will also be featured in M Night Shyamalan's The Last Airbender dropping pretty much at the same time at the beginning of July. I'll bitch about that movie later. There is a LOT to bitch about.
For now, this is Jackson with Twilight castmate Nikki Reed who has been largely undercover for the better part of 6 months, still reeling no doubt from the hate she received at the hands of vitriolic "Robsten" people who railed on her for her short affair with Robert Pattinson while he was waiting for Kristen Stewart. Nikki of course then took up with an old Ebola Paris Hilton victim for some rich refuge from the belligerating fans. Unfortunate decision. Because Ebola's infection runs deep and sadly Nikki doesn't seem to have much going on professionally either. See? Ebola's evil is never merciful.
Photos from Wenn.com and Jen Lowery/Splashnewsonline.com and Jason Merritt/Gettyimages.com


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a national Vice Chair for the National Association of County Agricultural Agents. More information of these ... gave presentations at a few programs across the state including the Columbus Dispatch Home and Garden ... the Forest College of Henan Agricultural University, to South Centers in May 2019. Dr. Lu has been ...
CD Wire- January 21, 2020
increasing urbanization is leading to proportionally fewer people producing food. On January 29 from 9:30 to ... books including Get Up Off Your Butt and Do It Now, Leading with Greatness, The Art of Communicating ... leadership development, strategic planning, legislative affairs, and youth and agricultural education and ...
East Ohio Women in Agriculture Conference
OSU Extension to Host 7 th Annual East Ohio Women in Agriculture Conference Ohio State ... University (OSU) Extension, the outreach arm of the College of Food, Agricultural and Environmental Sciences ... (CFAES) will host the 7th Annual East Ohio Women in Agriculture Conference. This year's conference ...
2020 East Ohio Women in Agriculture Conference
OSU Extension to Host 7 th Annual East Ohio Women in Agriculture Conference Ohio State ... University (OSU) Extension, the outreach arm of the College of Food, Agricultural and Environmental Sciences ... (CFAES) will host the 7th Annual East Ohio Women in Agriculture Conference. This year's conference ...
2019 eFields Regional Meetings
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WHO public health research agenda for influenza
The goal of the WHO public health research agenda for influenza is to guide research so that knowledge gained improves public health decision making in the prevention and control of influenza.
Biannual Progress Review and Report
In order to evaluate the impact of WHO's initiative to encourage research on better prevention and control of influenza globally, a biannual progress review was conducted. WHO Secretariat, with help from the scientific committee, identified high priority public health research topics from the five main research areas ('Streams') and commissioned literature reviews for each. Over 4000 citations of publications from 2010–2011 in more than 200 journals or other peer-reviewed publications were found through the literature reviews and database searches for this Progress Report.
WHO Public Health Research Agenda for Influenza - Executive Summary
pdf, 173kb
WHO Public Health Research Agenda for Influenza - Biannual Full Progress Review and Report with references
pdf, 2.73Mb
Influenza and Other Respiratory Viruses
Special Issue: Proceedings from the WHO Meeting on Global Research for Influenza
Download Appendices
Appendix 2 - List of publications, virus-specific factors associated with zoonotic and pandemic potential, 2010–2011
pdf, 93kb
Regional public health research agenda meetings
WHO public health research agenda for Influenza background documents
About influenza
- Infographic on seasonal influenza
- Fact sheet on seasonal influenza
- Fact sheet on avian influenza
- Fact sheet: Global Influenza Surveillance and Response System (GISRS)
Influenza virus infections in humans (update October 2018)
pdf, 239kb
Differences among seasonal, pandemic, and zoonotic or variant influenza


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Some weeks I find it difficult to carry the burden of knowledge of what is being done to parents and children in the UK. This is one of them. During the run up to Christmas, that most painful time of year for so many, the narratives and the lives of the people I work with and the faces of their children, stay with me through the night. Surrounded as we are these days in London, by the threat and fear of terrorism, it is unsurprising to me that my mind, usually resiliant, is unquiet. Like parents who live with the loss of their child, in the early hours, those small details of worry and anxiety cause me to be restless. Those of you who cannot sleep because of what you bear are not alone. I am here, in that place where the tides run restless, with you.
This week I have been witness to something so unbearable that unless it is expressed it will haunt me. This is the essence of what so many parents are grappling with in the midst of the loss of their children and it goes to the very heart of what is wrong with UK family law and, I guess, family law around the world. Dr Childress and his supporters will be glad to hear that what I am speaking about is his category of pathogenic parenting (what I call pure) and the terrible damage that it does to children. The unspeakable nature of this being the acts of utter violence and cruelty which are enacted within this pattern of alienation and the absolute futility of the family justice system's ability to stop it.
Children are being abused in the UK and we have no methodology to prevent it, no standardised services that even recognise it. All we have is a legion of people who believe in a political ideology and a handful of clinicians and practitioners who know that this is not the way to help those families where parents are, shall we say, less than psychologically well.
Let me tell you this story. Heavily disguised of course, but a true story of an act of cruelty so unspeakable that for days now I have carried this, unable to know what to do with it. I cannot imagine what it must mean to have to wake up every morning knowing that your children are in the care of someone who is capable of this.
Three children all reunited with a parent. One day the children asked the once rejected parent if they may be able to take a much loved treasure that they had also been reunited with back with them for a few days. The treasure never returned. If only that treasure had been held hostage by the vengeful parent. I think you can guess the real ending. The children involved have been party to an act of unspeakable cruelty and I am awake in the early hours because I know that the reason the children are so incredibly vulnerable to this, is because the other 'professional' in the case undermined my work and ensured the power stayed in the hands of the unwell parent. How can I sleep? How can that parent whose life has been utterly shattered sleep?
In the light of this, my unquiet mind tells me that it is all well and good for me to discuss with Dr Childress his pathogenic parenting and it is all well and good for me to recognise those patterns and call it pathogenic, pure or downright sadistic. What good does it do when we are up against the reality which is that these unwell people can manipulate the family services supposed to support children, in order to maintain their control over them. We have a vast number of social workers, Cafcass workers and other mental health people who simply treat all cases of alienation as a he said/she said situation. And in the midst of that young, vulnerable children are being exposed to the unspeakable cruelty which is their parent's desire for vengence.
What kind of madness is this, that our families are so regularly torn apart and the children within them placed with people who are capable of unspeakable acts of violence and supported to do so by political ideologues who (appear to me) to lack skill insight and empathy?
Tonight I cannot sleep. Tomorrow I will because the exercising of my unquiet mind and the processing of the helplessness I feel in facing this and being unable to stop it, will let me.
I imagine it will be a long long time before that parent sleeps through the night again.


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I took a road trip to Mayapur with my friends (Vineet, Shiv, Souresh) on 15 Aug 2008.
Labels: My Friends, My Photos, My Travels
Related to Things to do, before I die…
I would like to have a baby boy.
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This page is updated periodically. Last updated 11 Oct, 2008.
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CRESTVIEW � With the flap of a vinyl strip, a gentle shower of plaster dust and a clatter of dislodged wooden furring strips, a downtown architectural gem long hidden behind a plastic fa�ade was once more unveiled.
CRESTVIEW � With the flap of a vinyl strip, a gentle shower of plaster dust and a clatter of dislodged wooden furring strips, a downtown architectural gem long hidden behind a plastic fa�ade was once more unveiled.
The single-story commercial building on the 200 block of Main Street, now the site of Brad Stewart's law practice, is receiving a complete restoration. A $9,000 Community Redevelopment Agency fa�ade improvement grant administered by the Main Street Crestview Association is partially funding restoration of the building's exterior, which is estimated to cost $18,000.
"My family is one of the pioneering families in the area," Stewart said. "We're excited about tackling this project and what the final result will be."
Most interior renovation of the 1928 building, which appears on the National Register of Historic Places, is completed, Stewart said. The high ceiling is hand-planed tongue-and-groove pine. A period light fixture hangs in the lobby�s reception area. The floor is newly milled heart pine.
"We try to keep everything era-specific as best we could," Stewart said.
Some of the interior walls are reclaimed period brick. The conference room�s wooden door features carved wood ornamentation and is set with a large, stained glass window. Janet Hurst, a member of the local Gilliland family, gave Stewart the door, which used to hang in the family's home.
As workers from Brad Stewart's brother Jeremy Stewart's general contracting firm pulled down vinyl siding strips from the Main Street fa�ade, thick stucco, painted deep maroon, was revealed.
On the north side of the building's front, an unexpected treat surfaced: a long closed up door decorated with a 1960s butterfly motif had been preserved behind the vinyl.
"That was a real hidden gem," Brad Stewart said. "It was exciting to expose that door and see that picture there."
The doorway originally opened onto a long hallway, at the end of which was a dentist's office, he said. Main Street passersby had not seen the door in more than 40 years.
Stewart hopes to remove the stucco on the front fa�ade and restore the original brick.
"The plaster they used back then was so incredibly thick it may be damaging to try to remove it," he said. A patch of the almost inch-thick stucco remains on one of the interior walls to show visitors how thick it is.
Stewart is considering commissioning a mural for the north-side wall, which faces an alley.
As workers Tommy Rogers and Ronald Hilliard removed the vinyl siding, Stewart watched as old stucco and the location of old commercial signs were revealed.
"There are certainly easier ways to go about renovating an old building, and cheaper," Stewart said. "But we're trying as much as we can to make it authentic."
Contact News Bulletin Staff Writer Brian Hughes at 850-682-6524 or email@example.com. Follow him on Twitter @cnbBrian.


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If you think that the bankrupticies of the mid-sized California Stockton and San Bernardino are minor news in the grand scheme of things, think again.
The bankruptcies of these two places seem to have made one of the world's richest and most powerful men blink.
Warren Buffett's Berkshire Hathaway had made big bets on the health of municipal bond markets -- effectively wagering that all the dire predictions of municipal and state bankrupticies in the U.S. were overblown.
U.S. & World
News from around the country and around the globe
But in the wake of the California bankruptcies, Berkshire Hathaway terminated more than $8 billiion in contacts -- about half of this bet, according to the Wall Street Journal.
Why? Buffett in a TV interview made clear that he had been spooked by Stockton and San Bernardino. Their willingness to go into bankruptcy had made the once unthinkable possibility of massive municipal bankruptcies significantly more thinkable.
"The stigma has probably been reduced when you get very sizable cities like Stockton or San Bernardino to do it," Buffett said.
Buffett is a famous resident of Omaha, Nebraska, but he knows California well and spends significant times here. He owns a home in Orange County.
So if he's spooked by these bankruptcies, maybe the rest of us should be.
Lead Prop Zero blogger Joe Mathews is California editor at Zocalo Public Square, a fellow at Arizona State University's Center for Social Cohesion, and co-author of California Crackup: How Reform Broke the Golden State and How We Can Fix It (University of California, 2010).
Send us your thoughts via Twitter @PropZero or add your comment to our Facebook page.


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Travel Club & Business Opportunities
Fantasize Travel
Thursday, December 12, 2019 at 7:30 PM (Singapore Standard Time Singapore Time)
Event Details
*** Please Whatsapp Ryan at 9002 7441 To confirm meeting place and attendance ***
Join a community of life-enthusiasts whose thirst for adventure knows no bounds, poised to take a journey of self-discovery through shared experiences and the transformative power of travel. As an industry-leader in social travel with a diverse set of product offerings, we provide you access to thousands of curated trips to some of the most sought-after destinations worldwide through our transparent direct-selling model.
We believe the best way to experience the world is together... because together goes further. Welcome to DreamTrips.
What if the secret to a fulfilling and abundant life was as simple as doing what you love?
When you choose to join us, you become an integral part of a global family that supports and cares about you. We foster personal and professional development, and offer you the opportunity to earn extra income by selling products you can be passionate about — products that appeal to anyone who has ever dreamed of experiencing the world beyond their own backyard. We'll provide you with everything you need to market and sell travel and lifestyle membership that have already created joy for thousands of people around the world.
Welcome to our One Big Team. Your legacy starts here.
You are invited to this event by Ryan(Fantasize). Text to confirm at 90027441. By Invitation ONLY.
Come and see for yourself. If you do not like it. Well it's totally cool.
P/S: Just leave your credit card at home. No pressure. No hard sell. Come meet the community.
*** Please Whatsapp Ryan at 9002 7441 To confirm meeting place and attendance ***
When & Where
Suntec City Tower 3
Thursday, December 12, 2019 at 7:30 PM (Singapore Standard Time Singapore Time)
Add to my calendar
Fantasize Travel
Fantasize Travel is a organisation where events were created to pull together people with common interest, Travel, so that people get to travel more often and to more locations in a shorter period of time with Different group of friend. Travel deals at discounted rate at unbelievable price.
Contact/watsapp Ryan at 90027441


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Acetate Film Rolls
by Grafix
This high clarity, general purpose film is perfect for many commercial art applications. The film is an industry standard for overlays, color separations and layouts. Matte (frosted) on one side, this acetate is preferred when glare is a problem. Certified as 100% biodegradable.
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Paul F K. from Ocala, FL says:
.003 mil tears easily when cutting sharply curved pattern pieces. .005 mil works much better. I would prefer frosted both sides, but this is fine.
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As researchers learn more about how the body fights cancer, efforts are being made to turn the disease into the remedy. By using cancer cells to create vaccines, researchers are opening new doors to treatment and prevention.
On the following pages, you'll learn about cancer vaccines from our expert guest, Dr. Philip M. Arlen, director of the clinical research group and senior clinician at the Laboratory of Tumor Immunology and Biology at the Center for Cancer Research for the National Cancer Institute in Bethesda, Maryland. He talks about advances in cancer vaccine research, what makes vaccines such a promising new treatment option for cancer, and when cancer vaccines might be available for patients.
How Do Vaccines Treat Cancer?
Dr. Arlen:
A cancer vaccine is very similar to the vaccines that we received for childhood infections. It's actually not so much of a drug but a way of enhancing our immune system to recognize and fight illnesses. And basically the way these vaccines work is that the vaccine is given to an individual to try to elicit an immune response, to get the patient's own immune system to be revved up, recognize the cancer as a foreign target and then attack that.
The concept that we have used is that tumors actually can be vaccines in themselves in terms of turning the immune system on, but the cancers that grow in our body have ways of evading the immune system, hiding from the immune system and preventing it from being recognized. So coming in with a vaccine is a way of being able to train the immune system to see something that doesn't belong there and then attack it.
It's thought that we may be developing cancer cells over our lifetime throughout the body, and our immune system may be able to recognize those in small numbers and, through a process called immune surveillance, destroy potential cancer cells from forming. But in certain individuals and for multiple reasons, some of these cells can escape the immune recognition, start growing, and then as they grow become more evasive and start proliferating at much greater rates.
Will a Cancer Vaccine Treatment Soon Be Available?
Dr. Arlen:
Back in the early '90s, our understanding of immunology was really somewhat in its infancy. With the biologic breakthroughs and biotechnology, I think we have really made some great strides in understanding why the vaccines back then didn't work as well and how we could overcome these problems and make better vaccines. So I would actually use the analogy today that instead of a dog trying to bite a basketball we are probably more like a lion trying to bite a tennis ball. So I think we are really making some strides, but there is still quite a ways to go in terms of our scientific strengths.
We are very close now to approval of the first vaccine for cancer. There are a number of different vaccines that are now in what we call Phase III clinical studies. These are 'registration' studies [designed to meet FDA standards]. And if they meet their end points, meaning either [prolonged] survival or activity in terms of disease [cancer] shrinkage, I think we are pretty close to the FDA approving one or more of these vaccines. So when some of these studies have completed accrual, meaning all the patients have been enrolled, we should be getting information toward the end of 2009 or at least in 2010 about whether or not one or more of these vaccines will actually be approved.
Vaccines That Prevent HVP and Other Cancer-Related Viruses
Dr. Arlen:
Vaccines designed to prevent cancer are very similar to vaccines that are now on the market [to prevent] infectious diseases and childhood illnesses. We know that in certain situations, in certain types of cancers, there are certain illnesses that predispose us to cancer, and some of these are viral illnesses.
There has been a lot of interest recently in the human papilloma virus that is known to cause the majority of cervical cancers in women that are infected with it. What studies have shown is that if you vaccinate young girls before they are sexually active and they acquire this human papilloma virus, you can reduce the development of cervical cancer considerably. So in this particular example what you are doing is not going after the cancer that's already there but giving prevention for a viral illness that predisposes people to cancer. By preventing that virus from forming, you could actually prevent the cancer from occurring.
One of the vaccines (for human papillomavirus [HPV]) that has been approved by the FDA for the prevention of cervical cancer is Gardasil, and there is another, Cervarix [that is not yet approved in the U.S.]. Both Gardasil and Cervarix target these different types of human papillomavirus in terms of preventing cervical cancer.
There are also vaccines for other types of viruses that can predispose us to cancer. Hepatitis B is a virus that we have a vaccine for. What we are seeing with a lot of primary liver cancers now is that hepatitis C seems to predispose a number of patients to that condition, and there are vaccines being looked at, but nothing is on the market in terms of preventing hepatitis C. If we are able to come up with a vaccine that can prevent that, we can eliminate a number of diseases that patients get with their liver, cancer being one of them. So currently the preventative vaccines are targeting viruses or preventing viruses that have high predisposition to cause certain types of cancers.
Most of the preventative vaccines aren't, at this point, targeting tumor antigens or cancer cells. What they are doing is targeting diseases that have high predisposition for cancer developing. Work is being done with the hepatitis vaccines that can actually prevent potential cancer forming in the liver and some other organs. A lot of the HIV-related malignancies or lymphomas are viral-related, so viruses such as Epstein-Barr and even vaccines against HIV in and of itself can be considered vaccines against certain malignancies because of the high chance or likelihood of cancer developing in patients with these types of infections.
In Clinical Trials, Vaccines Have Been Effective Against Solid Tumors
Dr. Arlen:
Therapeutic vaccines are designed for patients who already have cancer. What we are trying to do is find certain targets that are known on that patient's individual cancer, and by understanding what those targets are come up with vaccines that can introduce those proteins on the tumor cells to the immune system at a far greater level. That's using the vaccine to try to kill off those cancer cells.
A broad spectrum of therapeutic vaccines are out there in clinical studies. What we have found is that a lot of these vaccines are now focusing in on solid tumors. I think if you go back to what Dr. Steven A. Rosenberg [of the National Cancer Institute] was working on in the 1990s, a lot of effort was going into melanoma because melanoma was not responding to chemotherapy and was felt to be an immunogenic tumor, a type of tumor that responds to the immune system. But what we found is that a lot of the common, solid tumors such as breast cancer, lung cancer, prostate cancer, colorectal cancer are actually immunogenic, and we are seeing responses in these vaccines being used against these more common types of tumors [in clinical trials].
It was felt a long time ago that solid tumors would not respond [to a vaccine] because the types of cells that make up solid tumors are so differentiated or heterogeneous, whereas the liquid [blood cell] tumors, or the lymphomas or leukemias, are of a similar type of cell that makes up the cancer. I think what we found is that there are effective new treatments for the hematologic malignancies (cancers of the blood and related tissues), with monoclonal antibodies such as Rituxan (rituximab) that really have increased response and survival rates in lymphomas. So the issue of coming up with a vaccine is now being focused more on the solid tumors where chemotherapy and radiation therapy only go so far, and the immune system may actually play a role by itself or even in combination to attack cancers with this type of mechanism of action.
Are There Side Effects to Cancer Vaccines?
Dr. Arlen:
There is a broad spectrum of vaccines. In general, the mechanisms are pretty similar in terms of making the body's immune system recognize the cancer and attack it, but there have been a number of different approaches in how the vaccines are being used. Some vaccines are proteins or peptides that are just injected into the skin, and generally speaking the side effects are really not much more than getting a flu vaccine. There can be some fatigue and injection site reaction, but in general they are not what we call cytotoxic. Hair doesn't fall out. Nausea or vomiting doesn't occur. They are pretty well-tolerated.
There are some vaccines that are also using what we call viral vectors, and those can be in some situations a little bit more toxic because some of these viruses can actually replicate and cause more local inflammatory conditions. So there can be some pain and even more flulike symptoms associated with those. But, in general, I would say that cancer vaccines as a therapy are pretty well-tolerated.
Could a Vaccine Treat a Malignant Brain Tumor?
Dr. Arlen:
There has been a lot of work in brain tumors in terms of using vaccine strategies. Currently, surgery and radiation and some of the chemotherapy drugs have been used for these types of tumors, but unfortunately we haven't made a dramatic amount of progress in curing or prolonging survival beyond a year or year and a half in some patients. There has been a look at taking whole tumor cells from patients and making vaccines from the brain tumor of an individual, and there have been studies using approaches with other types of known proteins on these cancer cells.
There have been some very interesting and intriguing results in early stage clinical trials. These trials are not very large in numbers [of patients], but of those patients who have gone on them we have now seen as recently as a couple of weeks ago presented at the large oncology meeting in Chicago (the 2008 American Society of Clinical Oncology annual meeting), that there have been results showing that some of these patients are living twice as long as what would have been expected without the vaccine. So I think there is a lot of promise for using the vaccines. And in this situation [a malignant brain tumor], it's usually done after someone has gone through the maximum surgery and radiation therapy to remove as much tumor as possible and then coming in with the vaccine when there is a lot less tumor burden than just using it by itself as a therapy.
It appears that vaccines work better when patients have the least amount of tumor, even microscopic disease, maybe after someone has had surgery or radiation therapy, and it appears that patients would respond better when their immune system is more intact. What I mean by that is that patients who have been pretreated or heavily pretreated with chemotherapy agents generally don't respond as well as those patients who have not had quite a few treatments, where their immune system is in better shape.
Are Customized Cancer Vaccines Better Than One-Size-Fits-All?
Dr. Arlen:
If you make a vaccine out of someone's individual tumor, you obviously know what the material inside that tumor is and the vaccine contains the target that you want to stimulate your immune system [against]. But there are some pitfalls in doing customized vaccines. Number one, they are expensive to have to take that material, bring it to a specified lab that the FDA would give permission to and make a vaccine to put back into an individual.
Number two, the actual techniques of being able to grow enough tumor cells and get enough material to make a vaccine that would work is questionable. It depends upon the surgical technique and how much tumor there is. It depends upon the processing, how many live cancer cells the laboratory technologist can pull out to make an effective vaccine. So there are a couple of variables.
I think the pro is that you know that the target is present, but the con is that it's sometimes difficult to make a vaccine in which you have enough of the antigen or tumor protein that would make it an effective vaccine.
The advantage to the 'one-size-fits-all' [vaccine] is that you can mass-produce those vaccines for all individuals. There is really never a question of whether or not you know how much material is in those vaccines because those all depend upon the manufacturing process. If you have a certain amount of cancer cells or cancer protein there, it's generally mass-produced at a level where each dose is the same coming out of the vial. So those are the advantages: that you always know that you have vaccine and you always know that the amount of material that you read on the vial is what you are giving to the patient.
Scientists Debate About What Makes the Best Cancer Vaccine
Dr. Arlen:
The debate [among scientists] is somewhat twofold. As I mentioned, whole tumor cell vaccines fall into two categories. There is what we call the autologous vaccine, which are vaccines made from an individual's tumor, and there are some benefits with that type of vaccine, but there are also some pitfalls.
The other whole tumor cell vaccines are what we call allogeneic, and those are usually actual cancer cells that have been grown in laboratories in what we call cell lines. They have been grown in culture for many years. The advantage to that is that there are plenty of tumor cells from which a vaccine can be made because those cells have been established, and they have been shown to grow.
How does that compare to the peptide-type vaccines, the non-whole-cell tumor? Well, the peptide vaccines usually use genetic engineering or recombinant technology. We know that the protein that's in the cancer is made up of a certain amino acid sequence. And if you know that a particular part of that protein can stimulate the immune system, if you inject a patient with that, you may actually get a response against that particular segment or fragment of protein called the peptide and get an immune response. So when the genetic engineering field took hold back in the 1990s, a lot of vaccines were made with this new technology of making peptides.
But since the early 1990s until today, we have learned a lot about the immune system, and we have learned that just one peptide may not be sufficient to stimulate the immune system enough to turn it on to attack the cancer cells. You may be able to get an immune response against that peptide, but we may not get a sufficient, strong enough response to be able to kill off cancer cells. How that's evolved is that a lot of the studies now using peptides aren't using just one peptide. They are doing peptide mixes so that they can get much more immune responses.
Which one would be better: the whole tumor cell or the peptide? The jury is still out on that. Until we do head-to-head studies comparing one to the other, no one can really say for sure that one vaccine approach is better than another.
How Standard Cancer Therapy Makes Vaccines Work Better
Dr. Arlen:
When somebody is diagnosed with cancer, and I will use the solid tumors, the common ones which are breast cancer and colorectal cancer, the approach to those is generally, if possible, having surgery done. Oftentimes if the disease is more advanced, chemotherapy or even radiation therapy is used. Generally, the three standard approaches to treatment of cancer are surgical, chemotherapy and radiation therapy in terms of how we attack cancer.
If you go back just a few years ago, the dogma was that these standard therapies are immune-suppressive and, therefore, we should never consider using vaccines with them. But as our knowledge and ability to test the immune system has developed, we have been able to show that therapies such as chemotherapy and radiation therapy at certain doses and certain timing and scheduling can actually enhance the immune system.
What I mean by that is that we now know that the cancer cell has the ability to down-regulate or make the immune system not function properly. Therefore, by using some of the standard therapies at certain doses or to a different schedule, we found that we can actually down-regulate the ability of the cancer to come up with these immune-suppressive mechanisms and allow for the vaccines to work better.
Which Cancers Are Best Treated with Combination Therapy?
Dr. Arlen:
We at the National Cancer Institute have looked at combining one of our cancer vaccines with a chemotherapy drug called Taxotere (docetaxel) in patients with prostate cancer. The initial study that we did was a proof of concept to show whether or not giving the vaccine with chemotherapy would enhance the vaccine, make it not work or do nothing. What we found is that you can give this particular chemotherapy drug with the vaccine and actually get improvement in the ability of the immune system to fight cancer.
We are now looking at this same approach in a larger clinical study with patients with breast cancer since docetaxel or Taxotere is a standard-of-care drug for the treatment of breast cancer, and we are doing a study now using the combination of vaccine with the Taxotere comparing it to the Taxotere alone. We are trying to see whether or not it makes a clinical difference in terms of improving the outcome by using the vaccine with the chemotherapy.
How to Participate in a Cancer Vaccine Clinical Trial
Dr. Arlen:
When I first came to the National Cancer Institute, since it's an institute that is based upon the development of studies and enrolling people in studies to test drugs, I was under the impression, and I think a lot of people are, that you go onto a clinical study because there are no other options. The patients have gone through what's available, and there is nothing left for them. And I think that concept is really false.
There are a lot of clinical trials now available for patients who do have options, and some of them are for patients who are healthy. They could have had cancer, and we are looking at a drug to prevent the cancer from coming back. Other examples would be combining a vaccine with chemotherapy, taking the standard approach and trying to make it better by using a vaccine or any other type of drug in a clinical trial.
So clinical trials are available for people who don't have other options, meaning that there is no standard therapy or someone has progressed through the standard therapy, but there are also a number of trials available for people with cancer, or patients who have had cancer, for either prevention or even early stage of recurrence.
To find out about clinical trials, there is a federal government Web site, www.cancer.gov, where you can search for clinical trials. There are a number of other Web sites, of course, but this is just one example of where you can put in any type of cancer, any disease stage, and it will give you a list of ongoing trials throughout the United States where there are studies being done for these different types of cancers.
More Information About Cancer and Cancer Vaccines
If you'd like to know about cancer vaccines, listen to the entire webcast of Cancer Vaccines: New Treatment and Prevention Options.
For more information about cancer, check out these HealthTalk resources:


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Sunday is Father's Day, and many consumers will spend this week seeking out the perfect gift for Dad. Whether it's the old stand-by gift to the latest electronic gadget, Better Business Bureau wants consumers to shop smart when searching for that perfect gift for the man in their life.
Depending on what type of activities your father is interested in, you want to make sure you're getting the best value. Always make sure to get information on refunds, exchanges and warranties in writing. Don't forget to get a gift receipt in case of any problems.
BBB offers the following ideas and tips for Father's Day gifts:
Gadget guy. Whether you plan to give him a camera, GPS, phone or other electronic device, be sure that you don't remove it from its box before wrapping it as a gift. Many electronics stores require the original packaging in order to process returns or exchanges.
Thrill seeker. If he's interested in renting an ATV or motorcycle, or going surfing or skydiving, be sure that you get a written contract that includes details such as the exact rental cost, daily fees, insurance and time restrictions. If you're referred to a business by a friend, check bbb.org to see if the business is in good standing.
Sports enthusiast. A ticket to his favorite event may be the best way for him to celebrate. Using a credit card or PayPal account provides additional protection and the opportunity for potential reimbursement in case of a cancellation.
Outdoorsman. Fishing, sightseeing, camping trips and kayak rentals are a fun way to spend time with Dad. However, it's important to get details about these adventures in writing and in advance of the trip. Be sure to clarify all of the factors listed below:
- Are reservations required? Are there any restrictions or special time requirements?
- Are taxes or any additional charges added?
- Are there any cancellation or refund penalties or policies?
- What services and equipment are included?
For the man who has everything. Gift cards may be the only option for your Dad. Be sure to check the terms and conditions of any gift card or certificate to ensure that the expiration date and any other conditions won't limit his purchase.


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Anabolic Cycles - how to stack anabolic steroids
Anabolic Cycles - how to stack anabolic steroids
With the increase in the use of anabolics, it is very important to understand and choose the right anabolic cycles to achieve the required goals. In the start, some physicians worked out on making the anabolic steroid cycles for many people including the sportspersons, especially the athletes so that these people get maximum benefits from them. Techniques were starting to get sorted out to minimize the negative effects but unfortunately this process keeps on getting done on the individual basis and that is the reason users had to develop their own cycles according to their specific requirements. There are many steroid cycles introduced and some are more effective than others are, and have given much better results. When you want to use steroids, the first thing that is of utmost importance is to make the right kind of selection for the steroid that satisfies your requirements.
Selection Criteria for Anabolic Steroids
The selection criteria for the anabolics differ for different persons according to their own specific needs. It is commonly seen that people normally gets confused while choosing the right kind of anabolics for themselves because anabolic steroids contains various kinds of medications. All the medications or drugs have their own characteristics, which are according to the specific needs of the persons. Some drugs are known for their low androgenic effects and their side effects are few in both the women as well as children. On the other hand, some anabolics are renowned to give a better functioning related to the sexuality of the men. The way of administration of anabolics also differs as some are used as injections while others are being handled orally. It is important to note that the limitations and side effects must be considered and sorted out well before use. It is very important and interesting to note that anabolic steroids deals and activate the same receptor that is cellular one, and all the anabolic steroids have the same properties related to the anabolization of proteins. However, many or few properties may differ and this helps in gaining the desired objective in a perfect way.
Perfect Muscle Mass and Strength
Anabolic steroids are normally used to gain muscle mass and to improve the strength of the body. However, it is important to note that there are certain advantages of one anabolic steroid than others, which makes it better. It is often found that the quantity and the quality of the muscle may be different using different kinds of anabolic steroids. Anabolic steroids can frequently increase the total muscle size drastically. There are some drugs which are thought to have no significant estrogenicity effect and that is the reason their size gains are less as compared to the others. The most popular steroid drugs are of two main categories namely, mass (bulking) and the lean mass.
Starting Anabolics Cycle
Normally in the start, steroid cycle is used with single anabolic steroid. People want to gain muscle mass and that is the reason they start taking steroids. Doctors advise the first time users to use the injections and they normally choose the oral compound for the sake of ease in their anabolics cycle. Stanozolol is among the anabolic steroids that are preferred by the people for gaining the lean mass.
Side Effects
While choosing any of the steroids cycle, adverse reactions must be kept in mind. Complete and specific consideration must be given, especially if a person wants to repeat the steroids use. The usage dose is also important in this regard, as it can help you in evaluating the kinds of positive and negative effects from the anabolic steroids. Usage of the anabolic steroids at the supratherapeutic level of dosage can give the best results indeed. It has been observed that the dosage range from 200 to 600 mg weekly proved perfect for efficient and effective muscle growth. However, quantity greater than this range can give you bad effects or adverse effects also which can be very harmful.
Cycle Duration
When you or your doctor chooses the required usage, then the main thing to consider is the cycle duration and normally anabolic steroid cycle is continued for six to eight weeks. During this time, the muscle rate increases. After that, it slows down significantly. Dosages can be treated as per requirements and if specific need arises, then you can increase the dosage but a consultation must be done with the doctor in that case. It is advisable not to extend the anabolic steroid cycle more than eight weeks at a time; and after some gap, the steroid cycle can be repeated to have maximum benefits but that must be done with the consultation of the specialist.
Recovery after Cycle Off
The period after the anabolic cycle is very important and it can involve the state of hypogonadism and due to its result protein catabolism can arise. Proper care must be taken to minimize the loss of muscle gained during the anabolic cycle. Some doctors advise to start the hormonal program in which a person can use the HCG and clomiphene for better results. Some people also use the strategy of reducing the dose of the anabolics rather than leaving it completely at once and that thing is called tapering.
Stacking of Anabolic Steroids
When a person gets used to the use of one anabolic steroid, he/she can start the use of more than one anabolic steroid. The technique is called stacking and it is in hot use nowadays. Stacking has gained its popularity normally with the body builders and they gain physical development more effectively that is not possible with the use of single anabolic steroid. Stacking became popular in the 1960s for the very first time. It is very effective especially when an anabolic androgen stack allowed people to use a high dose with a tolerable strength of single androgen. Stacking must be done with drugs that suits to the needs of the body of the specific person; otherwise, it is better to use the single anabolic steroid in a periodic manner to obtain the goals like mass maintenance and performance.
For bulk cycles, being a moderately strong muscle builder, nandrolone decanoate can be used with the classic " Deca-Durabolin and D-bol" stack (usually 200-400 mg of nandrolone decanoate per week and 20-50 mg of Dianabol per day) has been a bodybuilding basic, the "old school" for decades, and always provide excellent muscle growth.
For "brutal mass" cycles, stronger anabolic steroids such as Oxymetholone (Anapolon) or any Testosterone (Testosterone Depot Galenika, Testosterone propionate, Sustanone ) could be stacked with Deca-Durabolin, producing greater results, but with more water retention.


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Intensive Battles on the Horizon
To most people the odd premise of the Meatloaf song, "Two out of Three Ain't Bad" could be adapted into the stark reality and finalization of the next final weeks of the 2009 baseball season. Right now, this song can give the Tampa Bay Rays a musical punctuation mark to what must be done for rest of the season to realize their dream of taking this team into the postseason. And it is a good thing to envision and a positive thing to take two out of three games from your opponents, but what happens if you have only two games (Seattle) or a 4-game series ( Detroit/Baltimore/ Yankees) against an opponent? Do you then have to adjust to winning both of the two games, or three out of four games in that four game series?
Everyone seems to be starting to quoting those cliches right now of "Crunch Time" and "Must Win Situations" when chatting about the Rays chances. And to me it is all so funny because I have been voicing those concerns ever since April. I actually think that you set up your post season chances in the first three months of the season. Silly losses and unfocused moments rob you of wins that could be valuable right now. But in those early months of the season, people throw around phrases like the gospel according to ESPN that "It is early" or "Not to worry a 7-game winning streak can fix all of this".
And in those early months you can be that naive about the ending of the season. Because there was so much baseball to be played, to even thinking of having to buckle down and win at least 2 out of 3 of the rest of your games to get into a spot to claim a Wild Card berth seemed like odd vision in the early months. Funny, they could even go this route and still come up short of your goal. And to me that is the reality right now.
We need help to get to the post season. We truly do. It is not like this team is not competitive enough or strong enough to take on all comers to get there on their own, but they need help to step up the ladder and take that Wild Card berth. We have exactly 39 games left to our season. And we do have a huge important series lingering against team like Baltimore (8), Detroit (7), New York Yankees (7), Boston (6)and Toronto (6) that will shape the Rays dreams and aspirations for the postseason.
But maybe the remaining teams hidden on that schedule will be the deciding factors in this quest for the playoffs. There is one division in baseball that has handled not only the Rays, but the entire AL East this series in their series. The A L West again might hold the trump cards. The Rays are currently a combined 31-25 (.554) against the above group this season with all of their seasonal series games against Detroit still on the books. 25 of those 39 games are against team that are sporting a .500 record of above this season.
And 27 of those 39 contests are against our American League East foes. The Rays currently have a 27-18 (.600) record against their division in 2009. But not lost on the Rays is the fact that half of their final 32 games are played against the Red Sox, Yankees and Rangers, who all currently have great spot to enter the 2009 post season.
Those divisional games are important, and could be the fulcrum to balance the Rays towards a eventual Wild Card, but for some reason I am worried about a small set of 5 games more than the divisional tilts. The odd 2-game series against the Seattle Mariners and the 3-game series against the Rangers in late September in the hot box located in Arlington, Texas might be the last grasp at a chance to secure their goals. Those 5 games, not the divisional one could prove to be the teams downfall. And you know that this team has been simply miserable against the A L West division in 2009.
But I am not panicking or even about to spout defeatist venom yet. Sure this 7-game road trip envisioned by Rays Manager Joe Maddon to be the "Ring of Fire" could actually be the hot box they need right now to get into mental and emotional shape to grind out these last 39 games. But for their goals to still be on track, they need to take at least 4 or 5 of the seven games on the slate.
And there is nothing that Detroit would like better than to pop down the Rays because they could end up being an opponent in the playoffs. The Tigers would love to send the Rays back home with their barbs between their fins and have to regroup and reformulate a plan to get them to their goals. Right now there are a few teams sitting there waiting for their chance at us again knowing that a victory by them can end this Rays drama in 2009.
Now the Rays front office is already secure in the fact of offering our 2009 Postseason Ticket packet prices and options to us in the mail the last few days. In it I saw that the package in 2009 for my seat will cost me $ 1080. That is a bit higher than last season, but you have to admit, we have expected more out of this team in 2009. And this Rays squad has the talent and the abilities to thrust themselves right up into that Wild Card mess and make it interesting all the way to their last game on October 3rd against the Yankees at home.
And believe me, I do not want to be watching football during the weekends in October. I would rather be sitting in my seat at Tropicana Field seeing these same Rays fighting for a chance to redeem themselves on the World Series stage again. But in the Rays post season packet is the message that any money or tickets not used this postseason will be adjusted and placed in our accounts for our 2010 Season Ticket purchase.
And I have faith in their chances and abilities to again celebrate and enjoy their moments with the fans in securing a second romp into the postseason dance. I will send in my money hoping and praying for a chance to again sit there and maybe catch two more foul balls during the American League Divisional Series. I hope to be sitting in the Trop for a pivotal game in the ALCS, and might even have a chance to see another first pitch at a World Series game placed in the dome. If not, I know my money will be there for me to enjoy another year where promise and hope will reign heavy again in April, May and June.
14 Comments
Cliff – you are SO right! It is never to early to worry about how you will end the season! The games in April & May count as much as the ones in August and September! The next month and a half is going to be one wild ride in the AL East. I hope we all survive!
Not really worried about surviving right now.
Just trying to keep the boo-birds at bay really.
It is that time of the season where you truly know what everyone thinks by the way they address these final four weeks.
If they are positive, they have been with this Rays team for a long time.
If they are negative, they have also been with htis Rays team a long time, but see the pre-2008 fiasco on the horizon.
Rays Renegade
Every series for the Tampa Bay Rays is important, they need to step up or get out of this race. I think the Rays have enough firepower to do just that.
Matthew Tang
You gotta win series, and with the Rays beating the Rangers 2-1 in games this series' they got the upperhand. Keep it in 4 wheel drive and crash into the first place spot and take it from the Red Sox!
Tell you what.
the game tonight so far in Toronto is a firm example of that fact.
But Jeff Neimann is looking like he did in that first start in Baltimore. Got hammered then settled down and is owning the Jays in the 6th inning.
The Rays put up 3 runs in the top of the first were down 6-3 by the end of the second inning.
they have now bounced back in a wild and crazy game to take a 8-6 lead in the top of the 6th inning.
I just hope this is not going to be a typical Rays/Jays game this series.
Might need a stress relief toy to throw at the TV.
Rays Renegade
Tribe Ted,
You know something, maybe the Rays should just do their job with their heads down and grunt it out and see where they lie when they come home against the Red Sox next Tuesday.
After leaving Toronto we get to visit Comerica Park and will miss seeing ex-Ray Edwin Jackson on the mound during that 4-game series.
Fun, Fun, Fun until Daddy(Selig) takes the title away.
Rays Renegade
Love your last line there to the Beach Boys song! When I saw in the schedule that the Yankees play the Rays at the Trop for the very last series of the season, I said, "That should be a great one." These races could go right down to the wire. Fun fun fun is right!
Guess I have next Saturday night's last concert of the season on my mind right now.
And yes, it is the Beach Boys coming to the Trop along with the annual game taken in my the Tampa Bay area Parrotheads group.
Only thing better would be sand and waves in the outfield that night.
After tonight's victory, it is now 1-0 for the "Ring of Fire" 7-game road tour, then back home to battle the Red Sox and the Tigers again.
Rays Renegade
With so many important series, the Rays are going to either make themselves into a playoff team, or break into many pieces. They are looking good now, with that come from behind win yesterday night, but they need to keep it in neutral and bust down the highway. :)
Tribe Ted,
The way they did bounce back more than once last night shows that they have the ability to score when they need to most nights.
But I think the next three days will tell us a lot.
James Shields will pitch during the Blue Jay series, and Matt Garza will go Thursday in the first game against the Tigers.
Both have not gotten great run support from the team this season. This might be the perfect test to see if the Rays will ramp up their offense to help these two pitchers get "w's" for the team.
Rays Renegade
I hope Matt Garza throws at someone. That always wakes up the team. Carlos Pena is stroking the ball, and the Rays are looking golden. You are right on that though. The next three days WILL tell us alot about their playoff chances. Good luck! I have a new post up.
Tribe Ted,
Even tho he can be a headhunter, that is not the best use of Matt Garza for the Rays.
His stuff is maturing into some of the best stuff in the AL, and with time could be the ace of this staff.Anways, we are playing Toronto, which really would not brawl unless it is so intentional is is silly.
Plus, have you heard the crowd noise at their games.
It makes me wonder if they are awake or asleep while watching baseball some nights.
Very subdued crowd, but maybe that is theur style…let the baseball play out in front of them, then respond accordingly.
Rays Renegade
Well, I hope the Rays win all their games against Detroit. Yup, every single one the rest of the season :)-Erinhttp://plunking-gomez.blogspot.com
So far, so good. 2-0 on the road trip might be about right, but I still wish they did not choose to not show this game instead of the Sunday contest now mot showing on ESPN.
I am an optimist, and I can not see going 39-0, but if we even got near that, it would be enough to win the division for sure.
Rays Renegade


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valentine's day math activities candy hearts
Updated - Feb 2015 (grades k-3) valentine coloring pages back valentine s day themed math pages. TEACHING HEART S Valentine s Day Theme Unit!! Valentine s Day Lessons, Printables, Links, and Activities For Lovely Teachers!!! Valentine's Day is a special Holiday you can celebrate in your Sunday School classroom always remember that grade levels are not absolutes -- especially since we re all living in different countries and. Children can learn that Jesus loves them no matter what, and that we are mama's valentine's day worksheet packet has been updated for 2013! valentine's day worksheets from last year are combined with a few new pages to make a 14-page. Explore our collections of Valentine s Day recipes before the big day! Kraft Recipes has many Valentine s Day recipes for you to try this February with valentine's day coming up soon i wanted to start planning our activities for february. Valentine worksheets and Valentine games for preschool, kindergarden, first grade and second grade Valentine s Day worksheets, including Valentine coloring pages, word searches, crossword puzzles, writing prompt, activities, math worksheets, and more i combined a 10-frames set with an adorable valentine's day cupcake. Printable Valentine s Day worksheets for kids quick and simple valentine s themed early learning math ideas to try with kids. Check out our collection of kids Valentine s Day themed worksheets that are perfect for teaching in the classroom or early learning math ideas include counting, patterning and graphing! valentine's day e-books @ a to z teacher stuff's store how to make a valentine * valentine's mini-books * valentine's theme *. Lesson Plans for Valentine s Day making it easy for you: valentine s day workbook quick print kids pick pages to complete small book - easy handout and quick to print interactive valentine s day games for kids. Valentines Day activities and Valentine s Day lesson plan ideas, Valentine lesson plans, Teacher Resources, theme, unit, Use our Valentine s Day preschool printables for a fun thematic unit in your preschool classroom these online valentine computer games are fun to play during your valentine s day party. Below you ll find Valentine s Day Coloring pages, crafts, cards a fun craft for friends to put together for valentine s day, friendship day, birthday parties or any special occasion. We would like to show you a description here but the site won't allow us create one chain for the group or one for each. We are getting ready for Valentine's Day at Mess for Less funny valentine s day cards using jokes for kids. In that spirit, the kids have been exercising their creative muscles by making fun Valentines crafts such these cards are easy to put together and allow you little love to get creative without too much work! this glitter slime recipe needs only 2 ingredients! the red and pink colors make it perfect for valentine s day. I am in LOVE with these Valentine's Day centers! These centers are super festive for Valentine's Day and are all aligned to the common core! History of Valentine s Day, Valentine s traditions, candy hearts, mushy stories, and love poems on the Web Valentine s Day worksheets and coloring pages Coloring pages, Valentine-theme math pages, stationery, word searches it s super stretchy and tons of fun. (Grades K-3) Valentine Coloring Pages BACK Valentine s Day Themed Math Pages


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Ryan Maule needed a new logo design and created a contest on 99designs.
A winner was selected from 41 designs submitted by 14 freelance designers.
Using the existing colour scheme as a guideline, present your vision of the KeywordEnvy logo. The service is new, free and should have a fresh design.
KeywordEnvy lets you track your website keyword rankings in Google, Yahoo, etc.
Don't feel like you have to stick to the design I've got now though, I invite you to be creative! I do not necessarily want to use a "key".
I am happy with the overall design and colour scheme I have. I even like the style of my logo - but I need a real designer's touch. Please re-envision my logo based on the website colour scheme (green, orange, gray).
- Green (71B601)
- Orange (CC6600)
- A design element that can be turned into a favicon (16x16), the way I use the key part of the logo now
- I don't want exactly what I have now but with a different key.
- I don't want a glass table effect.
- I don't want to have too many "web 2.0" cliches.
Find out how a design contest works or learn more about our logo design services.


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The Dallas County Community College District (DCCCD) provides facilities for use by community groups when it does not conflict with college programming. The DCCCD and Eastfield College Pleasant Grove Campus reserve the right to determine use of the facilities commensurate with the District Board of Trustees' policies.
Priority for use of facility:
Facilities Request Form (pdf)
Community Room Rules (pdf)
Instructor Request Form (pdf)


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Entertainment Weekly has shared three new posters for Eddie Redmayne's next big project, The Danish Girl. Based on a true story and David Ebershoff's novel, the film follows the journey of artist Lili Elbe. Elbe was transgender and the first person to undergo gender reassignment surgery in the 1920s.
Tom Hooper is directing and producing the anticipated biographic along with producers Tim Bevan, Eric Fellner and Anne Harrison. Actress Alicia Vikander is playing Elbe's wife and is also featured in these gorgeous new posters.
According to IMDbPro, this project has been in various stages of production since 2010. The Danish Girl is currently set to premiere at the Toronto International Film Festival and the Venice Film Festival this September with a limited North American release set for November 27.
Stay tuned for the first official trailer and buzz from the festivals.
Sources: Entertainment Weekly and IMDbPro


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Elegant earrings recreated in earthy terracotta, inspired by the jhumka a heritage Indian heirloom crafted delicately in Green & Red shade.
Terracotta Jhumka Earring:
All designs are inspired by Nature and most of them are modified and taken from the temple traditions of India. Over the years the designs have been adapted to the changing needs of the Indian woman with a range of designs which are exquisite fashion accessory and extremely functional too. These delicate hand crafted masterpieces are a product of artisans from Bangalore. The classic design inspired by traditional Indian Jhumka in golden colour painted with multi-color detailing for effect.
* Please note Terracota accessories are fragile and we have taken utmost care to pack them in bubble wrap. Please note there might be a slight colour variation.
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