text:
Designing a Workplace for Ambitious Women
Talented women have plenty of drive, says Jody Greenstone Miller in a conversation with WSJ Weekend Review editor Gary Rosen. What they need is employers with the imagination to accept a new approach to structuring work.
This transcript has been automatically generated and may not be 100% accurate.
... I ... across America are reading Sheryl Sandberg's New Book Mimi and ... Sandberg's advice is that women need to be more assertive that work if they hope to rise in senior positions ... our guests today Judy Miller ... things that Sandberg is dry ... but isn't right in the most important way about what women need to do if a I went to rise ... in the ... best organizations in America ... so so tell me Jody what what is wrong or incomplete in what Sheryl Sandberg status and then how should we think about this problem differently ... well we shall say this is on ... it's true you know how it certainly can't hurt ... and something then Whitman again be on hold for many many many years I'm ... that the duty were serving go after what they want ... the problem is that that alone will not solve the problem that Cheryl realistically once the stock which is ... we need more women into leadership positions and in in my view the only way that I'll ever get solved instantly change ... when a means of what it takes ... to ride it out in corporate America and the leadership is is is that the in this piece you've written for weekend Revue you have ... several very ... concrete ideas about what that changed him upright and and I guess primarily in half to do with how we think about ... time ... especially for for a very demanding high powered job so so what what what what we need to do differently ... the ... guys that is absolute the Maritime ... acquired for top job today is whether the arrangements that's what's stopping women living in my opinion it's not ... they they don't have the ambition and talent ... so I think that ... I'd be there for example let's begin thinks that the first is ... the notion that someone has to work ... second a week for five days a week it's arbitrary ... um ... it is not based on anything and how many days there are are in in the week it fell and so they ... the first thing in the U S getaway and the idea that there's a ... certain minimum number of hours or days or months that person has to work in order to take on mission critical ... leadership roles ... the second thing we got to do is get to learn to wage war on ... in two projects into smaller bites said the people who come into her role ... in the top ... and be able to perform a in Italy ... that means you can think about work differently and you gotta play and ... I would have to get work done differently it's not ... aam is not rocket science but it is an app for and it's a lot harder than just throwing someone into a job and saying We're strategy can ... and we need a wall in the can and will be around what to do is to Jodie are you saying that when people are working in the company restructured this way they are available in the way that people are now or will their availability in some way ... differ from one stretch of work to another got to recognize that this difference between twenty four seven availability and twenty four seven workload ... they really are different and I'd be ... a reasonable to expect ... someone who's going to be a very senior leadership role in the organization to be in a bubble ... to be accountable for prices to be available for something that you need immediate attention ... that is very different than saying you must be able to work ... a workload that require C C seventy hours a week ... I think many professional women understand that your friends are willing to be available but don't want ... at twenty four seven work well ... and finally I'd be here is a very important cultural change aam probably even more important it would surely talking about in terms of women being more aggressive ... the notion ... that if you're not willing to work twenty four seven you were not ... even consider any player on the fact that many ... boardrooms and watched ... personnel reviews ... where one of the criteria for being in a play here is how are you willing to work ... and by definition you could be the best performer on a pro rata basis the company ... but you are not willing to work ... the level that currently are or why did you consider the player ... well I think that's got no eyes the quality is what matters not one of the million minimum number ... one get enough work to be significant move the needle ... but the notion that we are judging people and the air for ... putting any into slots which relate to their progress and seniority ... the company and now they're willing to work not ... only it were is one of the most important things we need to go the skeptics are going to look at this and they're going if a oh you know find what what he's saying is that people should be messing tenth less devoted to work ... is this going to work with demanding clients with difficult project ... does this mean that ... after ... eight hours of out of work ... and some of high power a Harvard MBA mom is going to say sorry soccer practice today ... and hand off work to some coworker in my experience that I start a company of the higher a lot of ... NBA is harder and see him hurting working ... on redesigning their jobs ... around the amount of time that they have available ... and what I have found is that these are mostly women ... they are incredibly unprofessional they would never ... stop something important for soccer game ... but it's my job to make sure ... we don't overload and because my dualism and so ... I think it is a different mindset which is you start to the job ... so that ... people can get it done in the amount of time you're comfortable committing to work ... and a new ... make sure that you enable them ... Sydney their professional goals as well as their personal very good Judy Miller thank you for joining us thank you for this piece which I think


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Coming May 1, take the Bike Month pledge!
Pledge to ride to school or work on Bike to Work Day, Monday May 27 and/or throughout June for a chance to win one of three trips for two courtesy of VIA Rail (to Quebec City, Montreal or Ottawa) or a weekend getaway courtesy of Welcome Cyclists. Contest closes June 18.

subset: commoncrawl


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Teen Choice Awards 2013
"And the award goes to…"
These are the famous words that anyone in the entertainment industry longs to hear. Glee's Darren Criss and Pretty Little Liars star Lucy Hale co-hosted The Teen Choice Awards 2013 which took place Sunday, August 11th at the Gibson Amphitheatre at Hollywood's Universal City Walk.
The venue featured two different entrances, one for fans and one for stars. Eager fans that were lucky enough to have tickets entered just to the right of Universal Studios Park, where they waited in a very long line.
Many of the girls wore dresses and heels while others sported casual trends. But everyone wore smiles, eager to see big stars and amazing performances. The line stretched around a large portion of the Universal City Walk, but the fans (many of whom voted for the awards) were energetic and excited for the event.
The second entrance was the red carpet area where the stars and nominees of the Teens Choice Awards showed off their style and personality. Behind the scenes, the stars posed for photographs, laughed and made jokes.
After the awards were presented, the winners were ushered back stage to an interview area where they answered questions and posed for photographs with their Teen Choice Surfboards. Many stars showed off their big personalities. It was truly an exhilarating experience.
And the WINNERS are:
Choice Music Group: One Direction
Choice Summer Tour: One Direction
Choice Single by a Group: "Live While We're Young," One Direction
Choice Love Song: "Little Things," One Direction
Choice Movie Actress - Comedy: Rebel Wilson, "Pitch Perfect"
Choice Movie Actor - Comedy: Skylar Astin, "Pitch Perfect"
Choice Movie - Comedy: "Pitch Perfect"
Choice Movie Villain: Adam DeVine, "Pitch Perfect"
Choice Breakup Song: "Come and Get It," Selena Gomez
Choice Music Star - Female: Selena Gomez
Choice Hottie - Female: Selena Gomez
Choice TV Show, Drama: "Pretty Little Liars"
Choice Summer TV Show: "Pretty Little Liars"
Choice Summer TV Star - Actress: Lucy Hale, "Pretty Little Liars"
Choice Summer TV Star - Actor: Keegan Allen, "Pretty Little Liars"
Choice TV Actor - Drama: Ian Harding, "Pretty Little Liars"
Choice TV Actress - Drama: Troian Bellisario, "Pretty Little Liars"
Choice TV Villain: Janel Parrish, "Pretty Little Liars"
Choice Athlete - Female: Gabby Douglas
Acuvue Inspire Award: Nick Jonas
Choice TV Show - Comedy: "Glee"
Choice TV Scene Stealer - Male: Chord Overstreet, "Glee"
Choice TV Breakout Star: Blake Jenner, "Glee"
Choice TV Actress - Comedy: Lea Michele, "Glee"
Choice Movie Actor - Drama: Logan Lerman, "The Perks of Being a Wallflower"
Choice Movie - Drama: "The Perks of Being a Wallflower"
Choice Female Artist: Demi Lovato
Choice Single - Female Artist: "Heart Attack," Demi Lovato
Ultimate Choice Award: Ashton Kutcher
Choice TV Actor - Fantasy/Sci-Fi: Ian Somerhalder, "The Vampire Diaries"
Choice TV Actor - Comedy: Jim Parsons, "The Big Bang Theory"
Choice TV Actress - Fantasy/Sci-Fi: Nina Dobrev, "The Vampire Diaries"
Choice Rock Group: Paramore
Choice Summer Song: "We Can't Stop," Miley Cyrus
Candie's Fashion Trendsetter Award: Miley Cyrus
Choice TV Scene Stealer - Female: Miley Cyrus, "Two and a Half Men"
Choice Breakout Group: Emblem3
Choice Summer Music Star: Bruno Mars
Choice R&B Artist: Bruno Mars
Choice TV Actor - Action: LL Cool J, "NCIS: Los Angeles"
Choice Music Breakout Artist: Ed Sheeran
Choice TV Personality - Female: Demi Lovato, "The X Factor"
Choice Summer Movie Star - Female: Sandra Bullock, "The Heat"
Choice Movie Chemistry: Sandra Bullock and Melissa McCarthy, "The Heat"
Photos compliments of Splash Magazine


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Oklahoma Speaker of the House T.W. Shannon will deliver the commencement address to Cameron University's Class of 2013. The annual graduation ceremony is slated for Friday, May 10 at 7:30 p.m. at Cameron Stadium. Following his address, CU's 2013 graduates will receive their diplomas. A fireworks display will cap off the occasion. The public is invited to attend.
"House Speaker T.W. Shannon is a distinguished public servant whose experiences and insights will guide our graduates as they look to find success in their own careers," says Cameron President Cindy Ross. "Coupled with Speaker Shannon's extraordinary talents and strong sense of purpose are his commitment to serving the State of Oklahoma and his exceptional leadership. Indeed, his life will serve as inspiration to Cameron University's Class of 2013."
Shannon earned a Bachelor of Arts degree in communication from Cameron University in 2000. He also holds a juris doctorate from Oklahoma City University Law School.
In a historic ceremony on January 8, 2013, Shannon took the oath of office to be Oklahoma's Speaker of the House, becoming Oklahoma's first African-American Speaker of the House and the youngest house member to ever hold that position. He hopes his mark is made by his quest to restore strong families, and to inspire the challenge of prosperity through personal responsibility.
Shannon's political career began when he worked as a field representative for former Congressman J.C. Watts and then for Congressman Tom Cole. In 2006, he was elected to the Oklahoma House of Representatives, the first Republican ever elected from District 62 and the first African-American elected to the legislature from southern Oklahoma.
Considered a champion for limited government, Shannon has more than earned the trust of his colleagues. He quickly rose to leadership in the state House, where he served as deputy majority whip in his first term, chaired the powerful transportation committee in only his second term and was elected speaker-designate in his third term.
He has been a champion for the state's natural gas industry, reducing the tax on compressed natural gas, a plentiful Oklahoma resource. He again made a mark recently by pushing to liquidate excess state-owned property. Shannon has earned high praise and editorial support from the state's two major newspapers. In the process, the trailblazing conservative uncovered that bureaucrats were grossly under-reporting the number of state-owned assets. T.W. also crafted an eight-year plan to rebuild Oklahoma's structurally deficient bridges.
He was recently appointed to the national advisory board of GOPAC, an organization whose mission it is to support up-and-coming Republican leaders.
An enrolled member of the Chickasaw Nation, Shannon previously worked as the chief administrative officer for Chickasaw Nation Enterprises. Today, he operates a home-based public relations business.
Shannon serves as a youth Sunday school teacher at Lawton's Bethlehem Baptist Church. He has been married to his college sweetheart, Devon, for 11 years. They have two children, Audrey Grace and Tahrohon Wayne II.
April 9, 2013


text:
Celebrating NASA and Space Explorers everywhere.
Now Playing: Mere Mortals - Lyricism Of Symmetry
Listeners: 42
Celebrate Space! A mix of ambient and experimental music mixed with the historical sounds of the space program.
If you don't want to use our webplayer, these links will work with external media players:
Celebrating NASA and Space Explorers everywhere.
Problems listening with the above links? Get a compatible media player here or try these alternative stream links for internet radios and other media players.
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text:
Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.
Don't have an account with us yet? Please set up an account to place order or obtain customer services.
Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide produced by tissue specific processing of the calcitonin gene and is the major product in neural tissues. CGRP is released by motor neurons where it exerts both short and long term effects on skeletal muscle fibers. In addition, sensory neurons release CGRP to the surrounding vasculature where it is partly responsible for local vasodilation following muscle contraction. CGRP acts through G protein-coupled receptors whose presence and changes in function modulate the peptide's effects in various tissues.
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I am a newbie to LaTeX. I noticed that my document is almost a page longer in Word compared to LaTeX. (~7.25 in latex, ~8.25 in Word). This seems to be because my Word document has 23 lines per page, where my LaTeX document has 27. I think the margins are the same (I set them to be, but haven't measured them).
The beginning of my document looks like this:
...and that's pretty much all the formatting I have.
Is the default "double spacing" in LaTeX/
setspace smaller than Word? How can I manually adjust this (in LaTeX)?


text:
Chicago's Congo Square Theatre Company is moving to Stage 773. The African-American theater company, known for the quality of its work and its administrative struggles, was formerly working at the Chicago Center for the Performing Arts, now leased to a church. It will now stage its shows in the newly renovated Stage 773, located at 1225 W. Belmont Ave.
Congo Square also said Friday that is was trying to put itself on a firmer organisational footing, naming Daniel Bryant its permanent artistic director and Ann Joseph-Douglas executive director. The duo had been running the company on an interim basis.
Despite several years of distinguished productions, the resource-challenged Congo Square has been quiet of late. And aside from the annual holiday production of "The Nativity," slated for the Goodman Theatre, there is not much of a 2011-12 season: yet, anyway. The first fully staged production, "Bulrusher," is not until next May.


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CORVALLIS -- Marcus Damas connected on an 18-foot shot with eight-tenths of a second left to give Towson a shocking 67-66 overtime victory over Oregon State on Saturday.
The Tigers (5-8), who got 20 points and a career-high 21 rebounds from Jerrelle Benimon, overcame a 19-point second-half deficit to force the five-minute extra period.
Ahmad Starks gave Oregon State (9-3) its first lead in overtime on a 3-pointer with 15 seconds left.
On the ensuing possession, Damas took a pass a few feet inside the 3-point line on the left wing and nailed the shot, quieting the Gill Coliseum crowd.
Eric Moreland had 16 points, a career-high 18 rebounds and six blocks for Oregon State, which had won five straight games. Joe Burton added 15 points and Roberto Nelson 14 points for the Beavers.
Towson, which had lost four in a row, trailed 44-25 after Burton made a layup with 16:06 left.
The Tigers answered, eventually closing within 47-40 on Benimon's basket off on offensive rebound with 9:13 remaining.
A layup by Towson's Timajh Parker-Rivera with 7:26 left made it 51-46 Oregon State. A basket by teammate Jerome Hairston on the next possession got the Tigers within three.
Benimon made it a two-point game with a layup, and Bilal Dixon's layin with 1:14 left got the Tigers back to even for the first time since the opening seconds of the game.
The teams then traded two free throws apiece, by Devon Collier and Benimon.
Oregon State had the final possession of regulation, with Starks missing a layup and Collier missing two close-in shots before time expired.
Benimon gave Towson its first lead of the game with the first basket of overtime. Teammate Rafriel Guthrie gave the Tigers a 64-62 lead on two free throws with 49 seconds left.
Oregon State's Nelson and Damas each made 1 of 2 free throws before Starks gave the Beavers their final lead of the game with his 3-pointer.
--The Associated Press
CORVALLIS -- Marcus Damas connected on an 18-foot shot with eight-tenths of a second left to give Towson a shocking 67-66 overtime victory over Oregon State on Saturday.


text:
Lab Created Diamonds
Lab created diamonds, also called cultured or engineered diamonds, contain the same chemical crystalline structure as Naturally mined diamonds while also exhibiting the same fire, sparkle and scintillation. Modern technology is able to produce engineered diamonds of exceptionally high purity and quality of which only the top two percent of natural diamonds can compare.
Additionally, lab created diamonds require no mining and therefore are a great choice for those looking to reduce their environmental impact. Cultured diamonds offer magnificent value and better affordability than natural diamonds.
the perfect diamond?
Search our entire collection of
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text:
EDITOR'S NOTE: The following is a condensation of an interesting
and informative two-part article, "Investment in Stocks and Shares,"
written by Mr. G.L.C. Touche for The Accountant, issues of
September 22 and 29, 1956, published in London, England. Mr.
Touche is senior partner in the firm of George A. Touche & Co.
* * *
INVESTMENT has its own universal tongue, but rarely is it as articu-late
or as readily comprehended as in the account presented by
our esteemed colleague, Mr G. L. C. Touche, for the British pub-lication
The Accountant.
In this remarkably incisive two-part article Mr. Touche points
out that it is impossible to divorce politics from the business of
investment today. Political risks, he believes, have replaced trade
risks as the determining factors in investing. He covers the broad
scope of investment facets discussing in turn the selection of
securities and sources of investment information; and he even
delves into the psychological foibles of placing money for gain.
Mr. Touche reveals his skill at diagnosing the ills of investment,
citing the pitfalls which, if avoided, can assure a healthier climate
for investments. For the accountant who is called upon to inform
clients on investments, he offers a thirteen-point guide list.
Although war is singled out by Mr. Touche as the number one
political risk, he also cites government action which can change
the entire economic picture of a country. In this latter classification
he enumerates nationalization, denationalization, and threatened
renationalization of industries; control of internal trade; control of
external trade; and the persecution of capital. Commercial risks
and market risks come in for a review by Mr. Touche.
Expressing definitive ideas on currency risks, Mr. Touche says
that "as intelligent investors, and particularly as accountants, we
should not be content with the profits on the books. . . . The steady
decline in the value of nearly all currencies is a major characteristic
of the age in which we live, and its bearing on investment policy
is profound."
Inflation he charges to "political ineptitude" saying that it is the
"automatic corrective of monetary mismanagement, and comes
from failure to resort to more positive cures. The financial mess
arises from excessive expenditure on unproductive projects, of


text:
Hey guys, how is everyone doing on this fine Saturday early evening. Well, evening where I live anyway. I wanted to start my drawing day by making and submitting a lesson that will show you "how to draw Naruto easy,", step by step. He is one of the most recognized faces on T.V., and in magazines around the world. There are so many different characters and people that I would love to make tutorials out of in easy form because I know that folks love following lessons that can actually teach folks the easiest way to draw their favorite figures. Anyways, this submission is going to be simple so I hope you're ready to be amazed. I just know that anyone who tackles this tutorial will succeed. Have fun folks and remember to keep those requests and suggestions rolling in.
DragoArt members upload artwork and drawing tutorials! They are also allowed to leave comments on tutorials, profiles, etc. Many more features, as well; it's way better than just being a boring guest! Register Now!


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Kelly Jorn Cook, DDS is a full service dental office in NW Chandler. We specialize in creating beautiful smiles in cosmetic and restorative dentistry, dental implants, and family dentistry. We provide the highest quality, personalized dental care for patients of all ages in a friendly, tranquil environment that looks more like a Rock & Roll Hall of Fame than a dental office.
Cosmetic Dentistry - Restoration Dentistry
Cosmetic and dental restoration dentist, Kelly Cook provides routine dental care, advanced cosmetic and complete restoration dentistry including dental implants, and general dental services for the whole family.
We are a fun loving team but we take your dentistry seriously. Kelly Cook constantly changes peoples' minds about what to expect from their dentist. An advocate for patient comfort and relaxation, his talent spans from sealants and fillings to the technical expertise of complete restorations and smile designs.
Sedation dentistry is offered as an option for patients who may be a little anxious or would just rather sleep through a procedure.
We are accepting new patients and you have Doc's guarantee ...
Dr. Cook's 5-year guarantee on workmanship remains in effect provided patients return for maintenance and cleaning, as determined by individual patient need, and as recommended and recalled by Dr. Cook.
Dr. Cook and his exceptional staff provide clear treatment plan options and preventative maintenance schedules specifically tailored to you, and will discuss all recommendations for maintenance with regards to individual patients' crowns, bridges and onlays.
True Dental Artistry
Kelly excels in blending artistry and technical ability to give you the smile you want and deserve!
Beyond great general dentistry, Kelly is recognized for his talent to create remarkable smiles. Increasingly, people are taking steps to have the healthiest, most beautiful smile possible.
Having an attractive, natural looking smile is an investment in you and is also an enormous asset. Changing your smile results in increased self-confidence and a positive self-image. A great smile communicates enthusiasm, warmth and happiness.
It is empowering to be able to flash your pearly whites with confidence. Redesigning your smile is life changing, and Kelly takes this artistry to a new level with every smile he creates.
A great smile speaks for itself. If you weren't born with the smile you deserve, Doc can make it happen.
Call Doc for a free dental consultation on any cosmetic or restoration procedure.


text:
Fun with Sphinx acoustic training. Boy, I wish I actually understood the math behind all this stuff. I guess that's what graduate school is for (most likely that's where I'll be in a couple years time).
For now, though, I'm going to enjoy some hacking on the implementation of it - the process (though it is inherently massively CPU-intensive) is taking a lot more time than it should and there are a lot of code cleanups to be done.
Computers are not really a hobby for me anymore. This is unquestionably a good thing in terms of my mental health, though I worry that I am not doing enough to maintain and improve my technical skills.
It was only a few years ago that I was a young liberal-arts student and self-taught hacker living off of student loans and struggling for meaningful employment, and I fear that, should things go wrong, my lack of formal education and credentials will come back to haunt me. I guess I can always go back to school.
In reality, things are actually going very well indeed for me; I work for a company with sensible management and finances, doing interesting work with real applications and customers. It's just that I have learned to survive by planning for the worst case scenario.
I'm worried about the perception that free software doesn't pay, and about the possibility that the demand for Linux/GNU/Perl/Apache expertise in the job market may be evaporating. I really hope that this is not the case, if not for my sake, then for the sake of people who might be in the same place I was a few years back; bright kids learning and using free software on their own time, who should have their efforts rewarded rather than repeatedly running into the "no BSCS degree, no job" barrier.
On the other hand, I am certainly glad that there will be no more bogus companies burning cash like Dubya, Cheney, and their oil buddies want us to burn oil, nor instant millionares and lazy people expecting huge payoffs. And speaking as a Canadian ex-pat, I'd be happy to see the outrageous salaries paid in the US be "corrected", so that perhaps the rest of the world will get a chance to keep its best and brightest.
Anyway, as I was saying, I've been splitting my spare time between my old and neglected interests of cooking, cycling, and homebrewing, and if you'll excuse me, I've got some bread to bake.


text:
sustained necesitaba un nuevo diseño de logotipo y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 143 diseños de 31 diseñadores freelance.
Masthead design for a glossy new magazine titled "new addressâ€, delivering inspiration and expert advice to property buyers, investors and sellers across Australia.
new address (more emphasis on address)
Desired Color Scheme:
Like other magazines, the colour of the masthead might change each issue
Desired Style:
Definitive, bold, creative and fresh - great typography is important
Accepted File Formats:
Vector Formats (.eps, .pdf or .ai); Please provide original Illustrator documents - .eps files please.
About the magazine:
Brimming with the latest products in homewares, inspiring ideas from leading interior designers and architects, "new address†magazine will provide real solutions, ideas and advice for home-savvy consumers who are in the market to invest in property and purchase exciting products for their new home.Â
We are looking for a fresh, clean, bold and creative typography design for the masthead of the magazine titled "new address†with more emphasis on 'address'. It will appear right across the top of the magazine which is A4 in size and like most other magazines the colour for each edition might change unless the typography used is prominent and memorable. If possible, please show us what it might look like on the front cover of a homemaker magazine.
Descubre cómo funciona un concurso de diseño u obtén más información sobre nuestros servicios de diseño de logo.


text:
Windows task retrorun.exe (retyped retrirun)
retrirun is propably a wrong typed name of process retrorun.exe.
Original process exe name: retrorun.exe
Name fragments: re, trorun, ret, rorun, retr, orun, retro, run, retror, un, ...
EUROBYTE TOOLS - cleans and speeds up your computer
You know it: the longer you own your computer, the slower it runs and the more often the stucks. Can I change it? Of course Yes. Try EUROBYTE TOOLS, program, that cleans and speeds up thousands of computers around the world. It's quick, automatic and effortless. So easy to use that even a beginner can use it.
Process cure
If you're looking for retrorun.exe instead of retrirun, visit retrorun.exe
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text:
The Accounting Historians Journal Vol. 14, No. 1 Spring 1987
O. Finley Graves UNIVERSITY OF MISSISSIPPI
Abstract: In his book Stabilized Accounting of 1936, Henry Sweeney differentiated his indexation model for accounting for inflation from the French and German inflation-accounting models of the 1920s by describing the European methods as "usually quite content to stabilize the paper-money book figures on the basis of merely some gold money." Sweeney's composite characterization of the Euro-pean thought, however, generalizes broadly and proves technically inexact when applied to the Germans. This study offers an account of the German gold-mark model of accounting for inflation as con-tained in the works of Walter Mahlberg and Eugen Schmalenbach.
Henry W. Sweeney's Stabilized Accounting of 1936 contains the first book-length treatment of inflation accounting to appear in the United States. In that book, Sweeney recommends a price-level-adjustment model for accounting for inflation that adjusts for price-level change by means of a general index. The ideas in the book, however, did not originate with Sweeney. Rather, as Sweeney himself acknowledged [1964, p. xliv], they had their roots in inflation-accounting methods previously de-veloped in Germany and France. Early in the 1920s Sweeney had chosen as a topic for a doctoral dissertation at Columbia University the overall valuation process, a process he found as currently practiced characterized by extreme conservatism. In attempting to infuse logic into contemporary valuation prac-tices, however, he reports finding himself repeatedly frustrated by the effects of fluctuations in the value of the dollar. As a result, he turned to Germany . Hyperinflation had only recently ended in that country, and he hoped to discover a solution to the problem of accounting under conditions of a fluctuating currency in what had been done there. As he set about mastering the German thought, the French, too, began to publish a body of literature on


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'Dead' on
Michael Rooker reaches for stardom on TV's hottest show
By Carl Kozlowski 03/21/2013
Michael Rooker is easily the most famous person ever to emerge from Jasper, Ala. And he owes the wave of fame he's riding now as a star of the smash TV series "The Walking Dead" to his combination of good ol' boy charm and a badass ability to kill zombies.
Despite the fact that he is easily the friendliest of the hundreds of celebrities I've interviewed over the past 16 years, Rooker is actually beloved for being one of the toughest character actors in Hollywood. Considering his first starring role was playing the title character of the horror cult classic "Henry: Portrait of a Serial Killer," that might not be surprising.
He's taken that innate ability to intimidate people with his gravelly voice and thousand-yard stare to the bank in more than 100 film and television roles, including the rare distinction of playing villains against three of the biggest action stars in the world: Sylvester Stallone, Arnold Schwarzenegger and Jean-Claude van Damme.
But his current role as Merle, the older of two zombie-slaying rednecks whose Machiavellian desire for survival can't always be trusted, last week led to crowds of international fans swarming him at the corner of Hollywood and Vine in Hollywood during a recent photo shoot.
He doesn't mind the attention, cackling as he's surrounded by two actors from England, three women tourists from Colombia, even an utterly ecstatic man from Bangladesh, all of them wanting to pose for pictures with him and begging for inside secrets from upcoming "Dead" episodes. This is as clear an example of Hollywood's power to shape world culture as one is ever likely to find.
"Nobody ever saw it coming," Rooker says later, leaning way back in a chair with a wide grin and sporting giant trucker sunglasses, a worn baseball cap with a cartoon of a beaver on the front and a sleeveless black leather vest over a worn T-shirt. "We started out with only six episodes, and that means they're not sure. But that first six kicked ass and blew up big time."
For the five or six people who may have not heard about or seen the show, "The Walking Dead" is an adaptation of a graphic novel series by Robert Kirkman, in which a former sheriff's deputy named Rick awakes from a coma to find that most humans have been turned into zombies. Rick gets taken in by a band of human survivors and helps lead the charge in the battle for survival.
The series was created by Frank Darabont ("The Shawshank Redemption," "The Green Mile") and is executive produced by Pasadena's own Gale Ann Hurd, who has overseen two power shifts at the show in less than three seasons, sparking reports that the production is riddled with behind-the-scenes tension.
Rooker declined comment on that aspect of the series, but in keeping with the idea that conflict can spark creativity, the show has not only met with wild critical acclaim but also the highest ratings in cable TV history, with nearly 13 million viewers. That easily places it among the top 10 series on TV, cable or network.
"We make the show natural and easygoing, and it's about the human condition and how people respond to emergency situations," Rooker says when asked about the show's massive appeal. "If you bring it to real life, it relates to how you would respond to a flood or an earthquake? What kind of human being do you become? Do you help others or run away? Every episode asks you to figure what you would do in that situation.
"The show asks who's right and who's wrong and is there an answer either way?" he continues. "But I don't care what people say. I just do it, get my payday and go home."
That laid-back attitude toward his busy career is surprising, considering Rooker is a highly trained actor who graduated from the elite Goodman School of Drama in Chicago, the city he moved to at age 13, when his parents got divorced. He admits that there are some movies "you pray will never be seen," roles that he's done "to pay the mortgage."
But, ironically, his breakthrough role as a slightly fictionalized version of notorious serial killer Henry Lee Lucas attained notoriety because he and his director John McNaughton put extra care into the production. That meant that what was intended to be a cheap slasher film became more deeply psychological and disturbing, making it too brainy for horror audiences and too brutal for mainstream filmgoers. "Henry" sat on the shelf for four years before it was released in 1990 to rave reviews that instantly made Rooker a hot commodity.
While he admits that his favorite way of dispatching the undead is by slicing them with his character's knife (aptly named "Little Merle"), he personally owns and travels with a gun when he drives cross-country to distant shoots.
In fact, so passionate is Rooker about guns that he co-owns the popular Angeles Shooting Ranges, in Angeles Forest, near Sylmar. As one might expect, he is not a fan of the government's current push for gun control.
"People who don't use guns don't understand guns and don't know they are a tool," says Rooker, the passion in his voice rising. "They don't understand that there's nothing wrong with hunting or being able to protect yourself and your family. They're fighting against the Constitution, the very document they're sworn to uphold, and that has got to stop."
Rooker smacks the palm of his hand onto the table as he makes that argument, but a moment later he's back to his usual wide grin and upbeat spirit as he sums up his attitude toward zombies and the success they have brought him.
"All that the zombies are wanting to do is to eat, walk around and maybe find a TV to stare at for awhile, so give them a break," he says, a grin slowly returning to his face. "I think all of it is too much for TV, but I love action and horror, and when you combine the two it's the best thing in the world. The fan base is amazing. We have little kids who are major fans. It becomes a family affair. I don't know how their kids are, but they're not afraid."


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Sasheer Zamata Gossip
Sasheer Zamata gossip, latest news, photos, and video.
The Rihanna brush-off
247PapsTV/ AKM-GSI/ Splash News
Rihanna was the musical guest for the season finale of Saturday Night Live last week. SNL cast member Sasheer Zamata, who's parodied RiRi before, livechatted this weekend about meeting her: "We had had a good night after the dress rehearsal, and she turned around and saw me and she was like 'Hey!' and she gave me a hug. Full Story
All the funny ladies, sort of
The 40th anniversary of Saturday Night Live is this month—there's a big special starring Justin Timberlake airing later this month—and as part of the celebration Glamour brought together some of the prominent women from the show's long history. Full Story
SNL works on that whole diversity thing
Late last year, SNL—and its executive producer, Lorne Michaels—got accused of having a diversity problem. There hasn't been a black woman on the show since Maya Rudolph left in 2007, and in the history of the show, they've only had four black women total, and in the whole history of SNL, there have only been fifteen black performers and two Latinos. Full Story


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Nate Berg
Nate Berg is a freelance reporter and a former staff writer for CityLab. He lives in Los Angeles.
For a city to be worth seeing, there must be something unique about it, said Douglas Coupland.
A Vancouver native, Coupland is an artist and novelist famous for his book Generation X. He's also the author of a number of non-fiction books, including City of Glass, which features a collection of essays about Vancouver. He's a proud Vancouverite, and though he argues that his is one of the greatest cities in the world, he told a crowd at the recent Cities Summit in Vancouver that his city and others need to do more to differentiate themselves from each other and from the digital world.
"The download revolution affects everybody, cities especially," Coupland said. "Your new competition isn't that city down the river with three-bedroom hotels and a slightly better golf course. Your competition now, for citizens and tourists, is World of Warcraft ... It is season-long bingeing fests of Breaking Bad and Downton Abbey."
Cities should celebrate the assets that only they have, and the embrace the fact that to see and experience them, people have to actually be there. He says our overly digital lifestyles are making physicality that much more crucial.
"The places that people are going to want to visit are those places that spark their imagination," Coupland said. "People want experiences that cannot be downloaded, however you want to define that. People want to see physical things and they want to do things with their bodies. You can't download a Henry Moore sculpture and you can't attach a ski slope to an email."
Coupland argues that emphasized difference is one of the new engines of the emerging economy, and that cities should embrace the local qualities that make them unique.
"Basically, my theory is take your fringe, make it into a fringe festival,: he said. "I've been in a few cities in my time where they looked at themselves and thought, 'what makes us different?' And then they amplified it and they became very interesting and visible in their own ways."
Speaking to a room full of city officials and urban practitioners, Coupland invited them to think more carefully about their cities' place in the world.
"Let me ask you: what makes your city different? How different is your city from the nearest competitor? If people were going to choose between visiting your city and that other city, what city is that? And if they chose that city, why didn't they choose your city? What do you have there that's different?" he asked. "Do you have a large Ukrainian community? Do you have lobsters? Do you have comedians? Do you have muscle-builders? Do you have apricots?"
Embracing these specialties and differences could be what make someone think about coming to visit or even moving to town. But ignoring what makes a place unique, says Coupland, will likely make it just another name on the map.
Photo credit: Nate Berg
A different kind of wealth distribution in 17th-century Amsterdam paved the way for its quintessential home design.
The pioneering festival marketplace was among the most trendsetting urban attractions of the last 40 years. Now it's looking for a new place in a changed city.
Looking at the population and job growth of large cities proper, rather than their metro areas, uncovers some surprises.
In an era of austere federal funding for urban public transportation, light rail seemed to make sense. Did the little trains of the 1980s pull their own weight?
In the cities where the most refugees per capita were settled since 2005, the newcomers helped stem or reverse population loss.


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Happy Black Friday! Enjoy this guide to saving big on Black Friday and beyond.
The posts I've linked to here will help you discover when and where to shop for the best deals as well as which toys are worth your hard-earned cash.
Start with a few basic tips:
- Early Shopper's Guide to Holiday Savings: Tips to Help You Save Big
- How to Pick Toys with Staying Power [and Avoid the Duds]
- This Year's Top Toys: Are They Any Good?
Find out what to expect on BF:
- Black Friday Ad Prices for Top Toys
- Baby Gear Deals for Black Friday: Jumperoo, Nautilus and More
- Kids Clothes Deals on Black Friday and Cyber Monday
- How Amazon Does Black Friday [2011]
These posts should help you determine if you've found a good deal:
And these posts should help if you just don't know what to shop for.
You can find the best toys by age:
- Toys That Get Played With 2011: 5 to 6 Years
- Toys That Get Played with 2011: 4 to 5 years
- Toys That Get Played with 2011: 3 to 4 year
- Toys That Get Played With 2011: 25 to 36 Months
- Toys That Get Played With 2011: 13 to 24 months
- Toys that Get Played With 2011: 6 to 12 months
Or let your conscience be your guide:
- Top 10 Green Toys for Babies and Toddlers
- Top 10 Green Toys for Preschoolers ["Buy" Prices, Too]
- Etsy Faves and Craves: Toys for Gifting
- Red, White, Blue and For YOU: Top Toys Made in the USA
And these should help if you're overwhelmed by the choices out there:
Whether you head out, or stay in on Black Friday, have fun! And remember, you can count on Baby Cheapskate to keep you informed about the best holiday shopping deals throughout the season!
This post may contain affiliate links. See BC's disclosure policy for more info.


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See our Candidate Privacy Statement
At Uber we don't just accept difference—we celebrate it, we support it, and we thrive on it for the benefit of our employees, our products and our community. Uber is proud to be an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.


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Check Rates or Reserve Now
Extended Stays
Please call 877-570-2267 now for special pricing on stays longer than 35 days.
Resort Overview
- Number of Sites: 407
- Open/Close: 01/01 - 12/31
- Need Help? Call: 877-570-2267
Whether you're taking a vacation in the Pacific Northwest or looking to make your RV home in Oregon, Portland Fairview RV Park is much more than a place to park your RV.
Located just 8 miles east of downtown Portland, Oregon, you will enjoy the peaceful setting while being close to all the restaurants, attractions and fun that Portland has to offer. While at Portland Fairview, take in the lovely landscaping found throughout the resort, wander amid tall evergreens and along the babbling brook as you unwind in the beauty of nature.


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View all 9050 A/H Pneumatic Timers
Pneumatic Timer, on delay, 0.1 to 60 seconds, 24 VAC 60 Hz, timed and instantaneousShow more characteristics
9050AO11EV01 has not been replaced. Please contact your customer care center for more information.
* Price is "List Price" and may be subject to a trade discount – check with your local distributor or retailer for actual price.
Price*629.00 USD
The maximum number of products that can be compared is 4
Main product range9050A/H product typeTimer timing modeOn-delay timing range0.1 s...1 min switch functionSPDT coil voltage24 V AC 60 Hz contact operationTime delayed 1 NO + 1 NCInstantaneous 1 NO + 1 NC current rating15 A Complementary maximum switching voltage600 V AC electrical connectionScrew-clamp terminals reset response time29 ms - on-delay27 ms - off-delay mounting supportPanel Environment ambient temperature range - operational20…40 °C (68…104 °F) certificationsUL listedCSA height2.64 in (67 mm) width4.02 in (102 mm) depth4.37 in (111 mm) Ordering and shipping details Category21631-9050 A ONE MINUTE PNEUMATIC TIMER Discount ScheduleCP1 Package weight(Lbs)34.77 oz (985.792 g) ReturnabilityNo Country of originMX Contractual warranty Warranty18 months
Technical FAQsNo results found.Unfortunately, related FAQs are unavailable due to temporary technical issues. Please try again later.


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TroopTrack is not affiliated with or endorsed by Boy Scouts of America, Girl Scouts of the USA, Baden Powell Service Association, Trail Life U.S.A., or Scouts Australia. Any usage of BSA, GSUSA, TLUSA, or SA terminology on this site is for informational purposes only and should not be interpreted as an endorsement of this product by any of these organizations.


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Email Us: email@example.com
Call Us: (020) 658 080 10
A Rose is the true embodiment of love. It is natures most beautiful way of showing us what true love is. Gift this bunch of 20 Red Roses, wrapped in Red paper, to someone and let them know how you feel about them.
Egg less
Qty :
1. Where do you want to deliver this?
2. Shipping option
3. When do you want the delivery?
4. Preferred time of delivery?
WITHLOVENREGARDS. All Rights Reserved.


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I have them waiting and I'll keep your secrete too
and what will you learn from this?
ouch....i thought someone who can help me on this site.. honestly i don't have a money to pay the programmer to do my thesis, that's why I post my problem here.. hmm instead of helping students like me, you want me to pay you $200 for your help!My GOD, I just want some help with the professionals who can help me.what if you are in my situation? what will you do?if you can't help me, just ignore me....this message is for those people who can understand my situation. thanks. but I don't have a money, I'm just a student...thanks Bainesbunch....
Quoteand what will you learn from this?That some people will do anything to make a buck or two.
this is the prototype of my thesis....I've tried some tips on the internet but i always got this error...avrdude: stk500_getsync(): not in sync: resp=0x00but this is just a arduino uno and GSM module...I don't know the perfect codes when i combined the smoke sensor + Arduino Uno + GSM module sim900...help me please
while (Serial.available() > 0) { char inChar = Serial.read(); if (inChar == '\n') { result = '\0'; Serial.flush();


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Citadel Ring Requirements
Ordering and Receiving a Class Ring
While any rising senior cadet may in the spring of the junior year be measured for and order a class ring, to be eligible to receive a class ring, a cadet must meet these two conditions:
1. Have an academic classification of 1A and
2. Have a cumulative GPA of at least 2.000.
To participate in the Ring Ceremony:
1. The cadet must:
Have passed the Corps Physical Fitness Test.
2. Cadets who have met requirements to receive the ring but have not met requirements to participate in the Ring Ceremony may pick up their rings at the Holliday Alumni Center on the first business day after the formal Ring Ceremony.
3. If a cadet fails to meet requirements to receive the ring with his/her class, the Alumni Association will normally hold the ring until the end of the following spring semester. If the cadet has not met requirements to receive the ring by that time, it will be returned to the manufacturer. The cadet may not order the ring again until all requirements to receive the ring have been met.
4. The eligibility of cadets who failed to meet ring eligibility in October of their senior year will be checked again in January.
5. The rings of cadets who have not yet received their rings but will receive their diplomas in May or will be eligible to participate in the Commencement ceremony will be cleared to receive their rings before Commencement. No other cadets will be cleared to receive their rings until after Commencement.
These are minimum requirements and will not be waived. Students should see the Registrar to confirm eligibility.


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Nearest Town: AtholSite Size: 7 miles long
Highlights: Raptors, Shorebirds, Songbirds, Upland Birds, Waterbirds, Waterfowl
Access: Year-round. Access free of charge.
Directions: From Athol, US 95 N for 4 mi to mp 453; L on Granite Lake Rd; go 1 mi; turn L on Kelso Lake Rd; travel 1.6 mi to Kelso Lake; continuing W on Kelso Lake Rd, bluebird country will begin when rd is bordered by open fields and continues for 7 miles past Kelso Lake.
Description: Spring and summer is the best time to visit. Virginia Rail can be seen and heard at Granite Lake. Look for Wilson's Snipe, Northern Harrier, Mountain and Western Bluebirds, American Bittern, American Redstart, and swallows along this route.
More Information: Hayden Chamber of Commerce (208) 762-1185
General Services:
Handicapped Services:What do these icons mean?
Select a species from the list to view other sites on the Idaho Birding Trail Sites this species may be observed.


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Dale A. Buckmaster, Editor
Edward M. Carney, et. al., The American Business Manual (New York: P. F. Collier & Son, 1914, 3 vols, of 384 pages each. Reprint edition: New York: Arno Press, 1979, $90.00).
Reviewed by Dale L. Flesher and Tonya K. Flesher University of Mississippi
The original aim of this three volume set was "to present the fascinating subject of business—the true romance of modern life—in a manner to add to the enthusiasm and zeal of executives and employees alike." The editor's stated purpose was "to present in compact, readable form all the essential principles of business organization and management, as well as the concrete application to the work of the various departments." Consequently, the volumes contain much more about business in 1914 than most people care to know. Thus, a complete reading of the books would be of interest only to someone desirous of a thorough background on American business during the early Wilsonian period. However, there are several accounting related chapters that might be of interest to accounting historians including the following: Taxation, Account-ing, Producing Costs, Depreciation, The Balance Sheet, and Audit-ing. These chapters are dispersed throughout the three volumes as there is seemingly little organization of the contents.
Some chapters were of less interest than others. For instance, there were only two pages on the federal income tax, but at least a dozen pages on tariffs. This is understandable since the tax rate at that time began at one percent and went as high as six percent on income above $500,000.
The numerous photographs and illustrations of accounting records were quite interesting. According to the caption of one photo, the use of a listing adding machine eliminated all chance for error. Another machine that was mentioned (in the chapter on Labor Saving Devices) was the check-signing machine. This device consisted of ten fountain pens fastened together. Thus, whenever


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I'm thinking of putting a few upgrades into my rig when I can afford the parts, but I'm not sure what things I can change for a cost effective and still powerful(er) set up. Currently I am running:
AMD FX-6350 6-core CPU
nVidia GTX-760 GPU
8GB DDR3 RAM (can't remember who its by)
430w PSU
Standard Fan cooling, no extras. Just bare bones interior.
I can run most games pretty well; Fallout 4 on Medium is smooth, ARK on Low can be tempermental (but then again its like that naturally), but recently stuff like GTA 5 after the latest update I'm getting lots of frame lag, hence why I would like to upgrade a few parts.


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This part contains general information about relational descriptors, as well as detailed information on how to create and configure these descriptors.
This part includes the following chapters:
Chapter 21, "Introduction to Relational Descriptors"
This chapter introduces concepts of relational descriptors.
Chapter 22, "Creating a Relational Descriptor"
This chapter explains how to create relational descriptors.
Chapter 23, "Configuring a Relational Descriptor"
This chapter explains how to configure descriptor options specific to a relational descriptor.


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Ever since President Obama was on the campaign trail, he has been derided by Republicans for vowing to allow the Bush tax cuts for the richest two percent of Americans to expire. And that's because, to Republicans, there are few things more important than the top marginal tax rate. And to hear Republicans tell it, marginal tax rates are the be-all and end-all of economic growth.
"We've seen over the last 30 years that lower marginal tax rates have led to a growing economy, more employment and more people paying taxes," said Speaker of the House John Boehner. "We also need to just cut the top marginal rate for individuals and corporations so that we're more competitive and companies can look way out in the future and know they'll have a competitive tax rate," said Sen. Jim DeMint (R-SC). "The economics profession has been really clear about this — higher marginal tax rates create a drag on economic growth," added House Budget Committee Chairman Paul Ryan (R-WI).
But is the data as clear as Ryan suggests? In fact, as Michael Linden, Director of Tax and Budget Policy at the Center for American Progress, found, "growth was actually fastest in years with relatively high top marginal tax rates":
Back in the 1950s, when the top marginal tax rate was more than 90 percent, real annual growth averaged more than 4 percent. During the last eight years, when the top marginal rate was just 35 percent, real growth was less than half that. Altogether, in years when the top marginal rate was lower than 39.6 percent — the top rate during the 1990s — annual real growth averaged 2.1 percent. In years when the rate was 39.6 percent or higher, real growth averaged 3.8 percent. The pattern is the same regardless of threshold. Take 50 percent, for example. Growth in years when the tax rate was less than 50 percent averaged 2.7 percent. In years with tax rates at or more than 50 percent, growth was 3.7 percent.
As Linden put it, "these numbers do not mean that higher rates necessarily lead to higher growth. But the central tenet of modern conservative economics is that a lower top marginal tax rate will result in more growth, and these numbers do show conclusively that history has not been kind to that theory." Indeed, these numbers put the lie to the common Republican refrain that Obama and Democrats in Congress are trying to implement a "job-killing tax hike" by putting the top tax rate back to where it was under President Clinton.


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Posted Jan. 3, 2007 – Terminal Velocity – It's so catchy, they used it as a movie title. But "terminal velocity" is an important science concept that affects meteors, mankind, and the mass-extinctions that keep changing our planet. Plus it's fun.
People who bewilderingly take up sky-diving learn that you don't just keep falling faster and faster. By spreading arms and legs, a jumper stops picking up speed when she reaches 120 mph. It's air, of course, that slows things down. Everything has its own terminal velocity: For raindrops it's 23 miles an hour give or take. That's the speed of falling rain, in case you ever wondered. (Actually it varies with the size of the drops. A light mist's particles might fall at only a half inch per second, which is why clouds, made of tiny droplets, can just hang there).
There is no terminal velocity on airless bodies like Mercury or the Moon. On those places, meteoroids captured by gravity keep gaining speed, up to a maximum that happens to equal that world's escape velocity, the speed necessary to wrench free from its gravity in a single upward blast. On Earth it's 25,000 mph. In other words, if there were no air and you FELL to Earth from a great distance, even beyond the moon, you'd hit the ground at that same escape velocity speed of 25,000 mph. Throw a coin up and then catch it. The speed you tossed it exactly matches the speed it travels when it lands back in your hand. Gravity is like that. Symmetrical.
At first a falling person or meteor keeps gaining speed. After each second of falling, a plummetting stone or person goes another 22 miles an hour faster. Two seconds of dropping, achieved by falling from five-stories, causes a rock to hit the ground at 44 mph. The speed would just keep increasing, up to that maximum of 25,000 mph, if we had no atmosphere. We've already seen that air slows skydivers to 120 mph, a speed reached after falling 500 feet or 50 stories. That's still fast, of course: The fatal human impact velocity ranges from 15 to 38 mph, so it's hardly news that we humans can easily die in a fall. But that's not true of all animals.
Some mammals like cats and squirrels have non-lethal terminal velocities. They can generally fall from any height and survive.
Here's where we get back to astronomy. An incoming meteoroid can easily weigh a ton as it strikes our atmosphere; that was the estimated weight of the intruder that broke into dozens of fragments over a Chicago suburb on March 26, 2003. One piece invaded a teenager's bedroom and broke a mirror. But it could have been much worse.
Meteoroids start out at a sizzling 7 to 44 miles per second relative to Earth. Fortunately, if the meteoroid weighs less than 8 tons — and nearly all of them do — air friction robs it of ALL its original speed. At a height of about 10 miles or 50,000 feet, it slows to just 2 or 3 miles per second, where it no longer glows. Nonetheless this 7,000 mph velocity, 3 to 6 times faster than a bullet, gives a one-pound meteor enough kinetic energy to easily destroy a jetliner. It hasn't yet happened, but it could.
Continuing downward, now dark and unobservable, the meteoroid's encounter with increasingly thick air slows it to a terminal velocity of about 240 mph. This is its final speed as it strikes the ground. That's the speed at which nearly all meteorites land, plus or minus 20%. That's still plenty fast – usually enough to pierce a roof and end up on the floor of some room. Buildings are penetrated every year or two in North America alone. Just since 2002, meteors have entered seven homes including two in the United States.
If the meteoroid weighs over 100,000 tons, our atmosphere won't slow it down in the slightest: It slams into the ground at full cosmic velocity. This isn't good, as the dinosaurs learned 65 million years ago. Yet even then, it's not all doom and gloom. The
big ones shake up the biosphere, change the course of evolution, and create new bio-adventures. We mammals now rule the Earth solely because a single impactor had enough mass to make it immune to — terminal velocity.


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I know this isn't Mets related, But I felt I had to honor a great champion.
I met Joe Frazier back in 1975 when I was 17. He was amazing. Very impressive. He autographed a few drawings for me. He said, " Wow, You're like LeRoy Neiman.Keep at it. I'm sure I'll see you again. " I left feeling great.
Now, I believe there are things that are meant to be. People meet because they are supposed to meet. Things happen for a reason. Nothing is a coincidence.
This past week I was supposed to do a signing with him on a limited edition piece from a painting I did. The other day I got a call from my publisher, who told me to send the pieces back. Joe wasn't going to be signing them.
Last night when I heard the news , a chill ran thru me.
I didn't get to see him. I guess it was almost meant to be.
Rest in Peace Smokin' Joe. I will see you again.
Tuesday, November 8, 2011
Tribute to Joe Frazier
3 comments:
That's a terrific drawing, Joe, and a great story.ReplyDelete
That meeting in 1975 was meant to be. Sounds like he provided some inspiration to you to pursue your artwork at a young age, and I'm sure it gave you confidence going forward.
You're smokin' with the brush and he clearly recognized your talent.
- AnonymousNovember 28, 2011 at 12:05 AM
anybody else expecting an illo for the new unis or the ballpark changes?ReplyDelete
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Ranolazine Oral tablet, extended-release
What is this medicine?
RANOLAZINE (ra NOE la zeen) is a heart medicine. It is used to treat chronic chest pain (angina). This medicine must be taken regularly. It will not relieve an acute episode of chest pain.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart disease
irregular heartbeat
kidney disease
liver disease
low levels of potassium or magnesium in the blood
an unusual or allergic reaction to ranolazine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush, or chew this medicine. Take with or without food. Do not take this medication with grapefruit juice. Take your doses at regular intervals. Do not take your medicine more often then directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
antivirals for HIV or AIDS
certain antibiotics like chloramphenicol, clarithromycin, dalfopristin; quinupristin, isoniazid, rifabutin, rifampin, rifapentine
certain medicines used for cancer like imatinib, nilotinib
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines for irregular heart beat like dofetilide, dronedarone
certain medicines for seizures like carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin
grapefruit or grapefruit juice
lumacaftor; ivacaftor
St John's wort
This medicine may also interact with the following medications:
certain medicines for depression, anxiety, or psychotic disturbances like bupropion, citalopram, fluoxetine, fluphenazine, paroxetine, perphenazine, risperidone, sertraline, trifluoperazine
certain medicines for cholesterol like atorvastatin, lovastatin, simvastatin
certain medicines for stomach problems like octreotide, palonosetron, prochlorperazine
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor for regular check ups. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. This medicine will not relieve an acute attack of angina or chest pain.
This medicine can change your heart rhythm. Your health care provider may check your heart rhythm by ordering an electrocardiogram (ECG) while you are taking this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
If you are scheduled for any medical or dental procedure, tell your healthcare provider that you are taking this medicine. This medicine can interact with other medicines used during surgery.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
fast, irregular or pounding heartbeat
feeling faint or lightheaded, falls
low or high blood pressure
numbness or tingling feelings
ringing in the ears
tremor or shakiness
slow heartbeat (fewer than 50 beats per minute)
swelling of the legs or feet
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
dry mouth
nausea or vomiting
stomach upset
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
March 21, 2017
U.S. FDA-approved Package Insert


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Monday, May 23, 2011
Greenville 1 - Swamp Rabbit Trail
7 comments:
Lovely, and I really dig those roots! WAHHOOOOOReplyDelete
Beautiful photos! Beautiful place!ReplyDelete
Love water scenes, beautiful photos.ReplyDelete
Hi Greta, thanks so much for stopping by my site Saturday; I appreciate this connection with you. I've enjoyed my visit to your blog this evening and I must say that your photos are WONDERFUL and the intricate roots in your last photo is so symbolic to our cause. Again, thanks!ReplyDelete
Of course I love the garden first. Would be afraid to walk on that walkway. Very nice park, and glad you found it.ReplyDelete
What a gorgeous trail!!!ReplyDelete
Thank you everyone for your comments - I am glad to "share" Greenville's beauty! This place is so good for the soul.ReplyDelete
Liv - You know, I hadn't even realized that when I posted the pictures of the roots - perhaps I will use that as a "byline" photo - thanks for the idea!
Barbara - They have master horticulturists who donate their time - a great community spirit.


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Organised Uncertainty
Since the 1950s, there has been a regulation in Egypt that requires half of all members of the Egyptian parliament to be "workers and farmers". This regulation will also apply to the result of Egypt's first free elections, which are due to take place on 28 November.
In the past, Egypt's parliamentary farmers were a very special breed indeed, and if the military, which has been ruling the country since Mubarak was ousted, has its way, they will remain so. After all, according to Amr Musa, Egypt's former foreign minister and secretary-general of the Arab League, 90 per cent of these farmers were retired army officers.
Although the election is only two months away, Egypt does not yet have an electoral law. The Supreme Military Council has already had three versions of a law drafted, and they all had to be withdrawn in the face of public pressure. Every single draft reflects the fact that the generals are striving to exert the greatest possible influence on the composition of the parliament.
For the first draft, the military quite simply adopted Mubarak's old electoral law. In accordance with this law, all members of parliament were elected as individuals (even though they indicated the party to which they belonged). The military claims that this system ensures direct contact between members and their voters.
But anyone not in uniform was up in arms about this first draft because it was clear to one and all that this law would open the floodgates to manipulation. It would mean that local notabilities with money, who had been part of the Mubarak system, would be elected to parliament.
The Muslim Brotherhood as unofficial junior partner
Ever since, the dispute has focussed on the so-called "independent members of parliament" who would not have to be elected via party lists. In the second draft law tabled by the military, these independent members would account for half of all MPs; in the third draft, this was reduced to one third. Independent candidates are an important tool for the military for several reasons.
Firstly, they prevent the emergence of a clear majority that could pose a threat to its power, which is why the draft law contains a passage that states that any member of parliament who is elected as an independent candidate and subsequently joins a parliamentary party automatically forfeits his or her mandate. Secondly, the military fears that politics will be defined by world views and political programmes. Thirdly, the military needs a legal lever that will allow it to shunt its people into parliament.
The secular parties, on the other hand, completely reject these "independent candidates" because they expect that such a system would allow major local figures who belonged to the now banned state party to return to the political arena.
The Islamists, on the other hand, are in favour of the most recent proposal regarding the distribution of seats in parliament. Because it is well organised and popular, the Muslim Brotherhood is confident that it will become the largest parliamentary party on the basis of party lists. At the same time, it is also confident that many men from the movement will also be elected to parliament as independent candidates.
In this constellation, the informal cooperation between the Military Council and the Muslim Brotherhood is apparent. The generals consider the Islamists to be attractive partners. On the one hand, the Islamists are legally vulnerable because their party could be banned at any time because of its roots in political Islam. On the other, the Muslim Brotherhood is enormously popular, a popularity that it has mobilised on more than one occasion in favour of the military council and its policies, the only social movement to have done so.
For its part, the Muslim Brotherhood, which was banned for so long, is now enjoying its promotion to unofficial junior partner of the generals. It now wants to prove to the generals that it is no longer a threat to the state order. Once in parliament, the brotherhood must show that it is ready to assume legislative responsibility.
Quite apart from an electoral law, Egypt also lacks the infrastructure necessary for the election, in which 44 million Egyptians are supposed to be able to take part.
But perhaps – and this is an assumption shared by many in Egypt – these uncertainties are all part of the military's plan. The more the election campaign and the election are overshadowed by uncertainties and the more vague the laws are, the more likely it is that candidates can legally challenge the results. This would give the military the opportunity to correct an undesirable result after the election.
An unexpected opportunity
It will be the parliament that will appoint the members of the constitutional assembly. Moreover, it is likely that a new Egyptian president will be elected in February. Here too, however, the electoral procedure is still unclear. Until such time as parliament and president are elected, the Military Council governs as it sees fit.
Its record so far has been frightening. Since February, over 12,000 young activists have been hauled up before military courts, which have sentenced many of them in fast-track proceedings. The law does not give them any chance to appeal their sentences.
Following the storming of the Israeli embassy on 9 September, the military reintroduced an even tougher version of the state of emergency that was in place under Mubarak. This state of emergency can also be applied to counter the "spread of false information", which leads to an intimidation of the press, which is now no longer free.
The generals are allowing the government to take action against non-governmental organisations on the pretext that the NGOs are being funded from abroad. Yet the security forces are taking no action against the groups of thugs (a relic of the Mubarak era), despite the fact that their members are known by name – and not just since the storming of the Israeli embassy either. At the same time, more retired generals than ever before have been made governors of the country's regions.
To balance this out, the generals are showing the court case against the toppled president Mubarak, which most Egyptians are following with relish. At the same time, it is becoming patently obvious that the military is using the humiliating exhibition of the old man as a means of settling an old score of its own.
Obviously a growing gulf had opened up between the officers' caste and Mubarak in recent years because the president had seriously disregarded the officers' economic interests by tolerating a new class of capitalist entrepreneurs among his son Gamal's acquaintances. He had also thrown down the gauntlet to them by trying to groom Gamal as his successor.
The mass protests in February gave the generals the unexpected opportunity they needed to rid themselves of the entire family, to accuse its protégés of corruption, and to re-establish their lost grip on power.
But all of this is certainly not without its risks for the military. For a long time, Defence Minister Hussein Tantawi, who also is head of the Military Council, claimed – as if butter wouldn't melt in his mouth – that he had known nothing of any Mubarak order to shoot at demonstrators. Recently, however, during a non-public court hearing, he said that he had not wanted to carry out that very same order.
Egyptians have watched the recording of this statement on YouTube over and over again and no longer want to believe anything Tantawi says. This being the case, it is impossible to say what the outcome of the tug-of-war between the Military Council and those who want a new Egypt will be.
Rainer Hermann
© Frankfurter Allgemeine Zeitung/Qantara.de 2011
Translated from the German by Aingeal Flanagan
Editor: Lewis Gropp/Qantara.de


text:
Google has shut down an email spam campaign that impersonated its online file service, Google Docs.
According to online reports - in particular, a detailed user thread on Reddit - clicking on an emailed share link, purportedly from a known source, was taking users to a site that asked permission for a fake app calling itself "Google Docs" to access their accounts.
If they agreed, the app would then send additional copies of the original email to the users' contacts.
Earlier reports suggested the attack was a phishing scam potentially aimed at harvesting personal information and maybe even Google login credentials.
But in a statement, Google said that while the campaign accessed and used contact information, no other data was apparently exposed.
Google said it was able to stop the campaign in about an hour.
It has disabled offending accounts, removed fake pages and updated its Safe Browsing feature, which issues warnings when users visit dangerous sites.
Users do not have to take additional action, although Google encouraged those who want to be extra safe to run its security check feature.
One telltale sign for identifying the spam email is that it appears to be directed to the address firstname.lastname@example.com and is only blind copied to the recipient.
Sarah Clark, from Leeds-based IT solutions firm Afinite, said:
'This is one of the most widespread phishing attacks we've seen. Typical phishing attacks would usually trick the user into handing over personal information, but this one was far more sophisticated. It bypassed the need to steal people's logins by building a third-party app which used Google's own processes to gain access to the account.
"What we're seeing is the evolution of phishing; they are getting more and more difficult to detect.
"Statistics show that 23 per cent of employees spend up to an hour a day on their personal emails whilst at work, so we are urging companies to review their security systems in place."


text:
Who should buy a budget wedding dresses – the bride or groom?
Who usually buys a wedding dress for the bride – about the real state of affairs.
Who should buy a budget wedding dresses – the bride or groom?
Who buys a budget wedding dresses – a modern look
Wedding dress, budget wedding dresses, may be purchased:
the groom
groom family
a family of the bride
parents of the newlyweds
the bridegroom with the bride.
Emancipation of women and budget wedding dresses
In the West, the emancipation of women has led many brides to pay for a dress, budget wedding dresses, themselves. Some girls, in addition, incur part of the cost of organizing the celebration – the services of a photographer, rent a limousine and a banquet hall.
Who should buy a budget wedding dresses – traditions and signs
In Latin America, the bride family traditionally purchases a wedding dress, budget wedding dresses. She also assumes the cost of buying shoes, veils, handbags, and other accessories.
If the groom family follows Eastern traditions, the groom or his family buy the outfit for the bride.
As for the signs, one of them says that the wedding dress, budget wedding dresses, should be bought by the bridegroom to the bride. But it is very undesirable that he saw him until the very celebration.


text:
You are here
What is a PMC?
- Definition of a Post Marketing Commitment
- Types of Studies carried out as Post Marketing Commitments
- Post Marketing Commitment Status Definitions
- Development process for Post Marketing Commitment Studies
Definition of a Post Marketing Commitment
As a requirement for the approval or continued marketing of medicines, US Food and Drug Administration (FDA) or the European Medicines Agency (EMA) may require additional information on a product to be generated, in the form of post marketing commitments (PMCs). These commitments are agreed to by a company with the health authority and are used to gather additional information about a medicine's safety, efficacy, or optimal use. Post marketing commitments can be required either before or after the health authority has granted approval to a company to market a medicine.1
In the EU, PMCs are also known as Post Approval Commitments (PACs) and may take the form of follow-up measures (FUMs) or Specific Obligations (SOs).
Types of studies carried out as Post Marketing Commitments
Different types of commitments have different objectives, different design and implementation needs, and different durations. Common commitment types include:
Clinical Trials – studies to answer specific questions about medicines, vaccines, new treatments or new ways of using known treatments. Clinical trials (also called medical research and research studies) are used to help determine the benefit/risk profile of new medicines and treatments. Carefully conducted clinical trials are the fastest and safest way to find what medicines and treatments work, and to understand any potential limitations to their use.2 Types of clinical trials include:
- Randomized clinical trials (RCTs) – Studies of the efficacy and safety of a drug within a limited patient population. Patients are randomized to study treatment in an effort to make the treatment groups balanced and comparable, extensive inclusion and exclusion criteria are often applied, and patients are followed for a certain period of time to determine whether they reach pre-specified study endpoints. The sample size for RCTs is often on the order of a few hundred.
- Drug interaction studies – Studies of the modification of the effect of a medicine when administered with another drug. The effect may be an increase or a decrease in the action of either substance, or it may be an adverse effect that is not normally associated with either medicine.2
- Efficacy studies – Studies assessing the effectiveness of a medicine at the dose tested and against the disease for which it is prescribed.2
- Large simple trials (LSTs) – These studies include large numbers of people (typically several thousand) and extend over a long period of time, typically many years. These studies use broad eligibility criteria, simple enrollment procedures and are intended to study the safety and/or efficacy of treatments under "real world" conditions of use.3
- Pharmacokinetic and pharmacodynamic studies– Pharmacokinetics (PK) measures processes such as drug absorption, distribution, metabolism and excretion in living organisms.2 Pharmacodynamics (PD) is the study of a drug's biochemical and physiological effects, the mechanisms of the drug's action and the relationship between the drug's concentration and effect.4 PD may be characterized as the study of what a drug does to the body, whereas PK is the study of what the body does to a drug.
- Safety studies – Studies determining incidence of adverse reactions when adequate instructions for use are given, and potential for harm under conditions of widespread availability.5 Phase 4 post marketing studies may assess safety in larger populations over broader timeframes, as compared to Phase 2 and Phase 3 studies.
- Completion of ongoing study – Completion of clinical trials in progress at the time of regulatory approval may be required as a post marketing commitment.
Pediatric studies – Studies of conditions and treatment in children. Types of pediatric studies may include:
- Efficacy studies
- Pharmacokinetic and pharmacodynamic studies
- PREA studies – In the United States the Pediatric Research Equity Act of 2003 requires new drug applications (and supplemental applications) to contain a pediatric assessment.6 At the time of regulatory approval, these pediatric studies may be required as a post marketing commitment.
- Safety studies
Safety studies – Safety studies may be conducted in several forms, and may be carried out to evaluate the safety of a medicinal product.
Special population studies – Studies of specific sub-groups within a larger population, such as pregnant women, children, geriatric (elderly) patients, patients with specific disease characteristics, such as liver (hepatic) impairment or kidney (renal) impairment, or patients with specific reactions to treatment, such as change in QT interval (heart rate measurement).
New dosage form/strength studies – Studies testing different dosage forms/strengths or delivery systems.
Other types of studies can include:
Pre-clinical studies – Testing of medicines in the test tube (in vitro) or in animals. This typically occurs before trials in humans may be carried out, but may be required at any time.2 These studies may examine carcinogenicity, microbiology or toxicology.
- Epidemiological studies – Non-interventional studies of incidence, distribution and control of a disease in a given population.2 Epidemiological studies can also be designed to evaluate drug safety.
Other types of Activities to Address a Specific Commitment:
- Safety registry – Generally non-interventional studies, registries are repositories where data, records or laboratory samples are kept and may be made available for research or comparative study. For example, physicians may maintain lists of patients who share a characteristic, such as a medical condition or medication regimen.5 Safety registries capture and document ongoing safety and outcomes data in patient populations under real-world treatment conditions. Other types of registries include disease registries, drug registries and pregnancy registries.
- Other types of activities to address a specific commitment may include for example, a labeling comprehension study, a commitment to convene an expert panel, or an education program.
US Post Marketing Commitment Status Definitions
Post marketing commitment progress is reported on this website using the following status descriptions [(consistent with the definitions used in the US by the FDA)]:1
Pending – The commitment has not been initiated (i.e., no subjects have been enrolled or animals dosed), but does not meet the criterion for delayed (i.e., the original projected date for initiation of animal dosing has not passed).
On-going – The commitment is proceeding according to, or is ahead of, the original schedule. A study will be considered to be on-going until a final study report is submitted to the health authority, as long as the activities are proceeding according to the original study schedule. If patient accrual or animal dosing has started but is not complete, and the projected date for completion of that milestone has passed, the study should be categorized as delayed.
Delayed – The progression of the commitment is behind the original study schedule. Delays can occur in any phase of a study, including patient enrollment, analysis of study results or submission of the final study report to the FDA. While the original study schedule — not a revised schedule — serves as the basis for defining a study as delayed, each phase of the study will be considered in its own right. If the company has one delayed phase, but gets back on schedule during the next phase, the delayed status will no longer apply.
Terminated – The company ended the study before completion, and has not yet submitted a final study report to the FDA.
Submitted – The company has concluded or terminated the commitment and has submitted a final study report to the FDA, but FDA has not yet notified the applicant in writing that the study commitment has been fulfilled or that the commitment has been released.
Fulfilled – The company has submitted the final study report for the commitment, and upon review of the final study report, FDA is satisfied that the applicant has met the terms of the commitment.
Released – FDA has informed the company that it has been released from its obligation to conduct the post marketing commitment because the study is either no longer feasible or would no longer provide useful information.
EU Post Marketing Commitment Status Definitions
Pending – The commitment has not been initiated.
On-going – The commitment is proceeding according to, or is ahead of, the original schedule.
Delayed – The progression of the commitment is behind the original schedule.
Terminated – The commitment has been terminated.
Submitted – The company has submitted the required information to the Agency but has not yet been notified that the commitment has been fulfilled.
Fulfilled – The company has submitted the required information to the Agency and upon review of the Agency is satisfied that the applicant has met the terms of the commitment.
Released – The Agency has informed the company that it has been released from its obligation to conduct the post approval commitment.
The Development Process for Post Marketing Commitment Studies
Protocol development – A protocol is a study plan on which all studies are based. The plan is carefully designed to safeguard the health of the participants as well as answer specific research questions. A protocol describes what types of people may participate in the trial; the schedule of tests, procedures, medications, and dosages; and the length of the study.2 Protocols apply to pre-clinical, epidemiological and outcomes studies as well as clinical trials. Upon receipt of a post marketing commitment notification for a new study, a protocol must be designed to fulfill the requirement. This may involve additional consultation with the FDA and/or the European Medicines Agency to gain agreement on the study required. During the protocol development period, the status of a commitment is defined as pending.
Investigator start-up – At Pfizer, investigators (researchers) and study sites undergo a thorough initiation process requiring submission of information and extensive review before beginning a study. Pfizer follows standard operating procedures for investigator initiation, including review of study site documentation, Institutional Review Board or Independent Ethics Committee approval, investigator training and initiation meetings. During investigator start-up, the status of a commitment is defined as pending.
Subject recruitment – This is the process of screening and enrolling a predetermined number of subjects for a clinical trial or an epidemiologic study. All such studies have guidelines about who can participate. Using inclusion/exclusion criteria is an important principle of medical research that helps to produce reliable results.7 Recruitment rate may affect the completion timeframe of a study.
Conducting a study – Studies must be conducted in accordance with ethical principles, regulatory requirements and standard operating procedures. A study team manages all aspects of study conduct, to assure that patients' rights, safety and confidentiality are protected, that study data are accurate, complete and verifiable, and that the study is conducted in accordance with the protocol, and ethical and regulatory policies. Study results are reported in a Clinical Study Report (CSR). Data undergo rigorous quality control and quality assurance review procedures. The final CSR is then submitted to the appropriate regulatory authority, as required, for careful review and assessment of the data. When a study is being conducted, its status is defined as on-going. When the final CSR is submitted to the FDA and/or European Medicines Agency, the status will be revised to submitted.
Reporting PMC progress – Pfizer tracks the progress of its post marketing commitments in the US and for products approved via the Centralized Authorization Procedure in the EU in its internal repository (database) for post marketing commitments. Pfizer updates the FDA on commitment progress in annual reports, and at specified milestones in clinical trials. Pfizer keeps the European Medicines Agency updated on any information pertinent to their PMCs and at specified time points in accordance with individual post-approval commitments.
1 U.S. FDA Postmarketing Study Commitments website.
2 Clinicaltrials.gov Glossary.
3 AIDS Education Global Information System.
4 Goodman & Gilman's Pharmacological Basis of Therapeutics.
6 U.S. FDA Pediatric Drug Development Index.
7 Clinicaltrials.gov Introduction to Clinical Trials.
About the Information Posted on This Web Site:
This Web site contains information about Pfizer's post marketing commitments for pharmaceutical products in the US and for medicinal products approved via the CAP in the EU. The post marketing commitments listed here include pre-clinical, clinical and epidemiological studies or testing and for the EU other activities agreed to by Pfizer (including its group companies/subsidiaries) and the FDA or European Medicines Agency, and are used to gather additional information about the safety, efficacy, or use of approved Pfizer medicines, or help ensure their safe use. This Web site provides the current status of Pfizer post marketing commitments listed on the FDA Web site. It includes post marketing commitments established for Pfizer medicines in the US since August 1, 2000 and for EU medicinal products approved via the CAP. New post marketing commitments will be added to this Web site as they are established.
This Web site does not contain technical chemistry, manufacturing and control (CMC) commitments, or commitments for medicines for which a Pfizer group company is not the license holder. Information about Pfizer's post marketing commitments is believed to be correct at the time that the information is posted, and is subject to change as progress is made in fulfilling the commitments.
This Web site is updated monthly. The status of post marketing commitments shown on the FDA Web site may differ from information displayed on this site, due to differences in the timing of updates made to the FDA Web site. The number of commitments on the two sites may also differ, due to the frequency of such updates and/or due to multiple reporting of single commitments on the FDA Web site.