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Biblical Theism
Thus we have reached the point in our discussion where we have to part ways with all exclusively philosophical methods of settling the question of the will. We have found that no metaphysics is available that can serve as a foundation for an adequate view, or rather that itself expresses an adequate view. At the last we even reached the conclusion that we shall have to choose definitely between the alternative of building on natural reason and, if we be logical, turn to despair, or admit that we must get down from our pedestals as judges and let God pronounce judgment upon us. This sounds like moral terminology but it has equal force epistemologically and metaphysically. Hence we must choose. We may feign to let the various theories of epistemology pass before us and judge them upon their merits, but in actuality we cannot do so. If we speak of our reason as the impartial bar of judgment we have already taken sides. We have then chosen ourselves as an absolute and final standard. Equally, on the other hand, if we chose to accept special revelation we have used our reason. It has declared itself bankrupt. But it is exactly here that the difference between the two roads becomes clear because he who accepts the fact of sin at the core of his being, posits a force entirely independent to himself to be moving him. We may for the time being call this only an external force, which we shall later find to be the Holy Spirit, because for the time being we are concerned only with the absolute necessity of choice between two principia, this term being taken in a pregnant sense. Either we ourselves shall ultimately determine what is our nature, the nature of God, or we shall accept the opposite principle that God must determine. Since it is for us impossible to take the stand on our own human consciousness because that can at best lead to illusion, we must choose the other. Not as though because we now see the logical untenability of the philosophical position do we finally take the choice. That would be in the nature of the case impossible. That would again be lifting ourselves by our own bootstraps, and our attempt to do so would be the denial of the necessity of a higher power, and we would still be on our old standpoint. Hence it follows that if God is to determine the relation between himself and us, he must be the originator in drawing us out of our own position.
Before we can even begin to work out the question of the will in its theological relations in the more technical meaning of that phrase the problem is thus, as it were, thrust upon us unawares, who is to decide. Either we must decide that we shall determine or that God shall determine. If we determine to decide for ourselves we have already by implication taken a stand on the relation between God and man. We have then refuse to accept two things. First, we have decided that sin is not of such a nature as to render us incompetent as judges. Secondly, we have refused to accept the position that the infinite must determine the finite. By virtue of the first we have refused the actuality and necessity of divine working upon us in the moral sphere and have thus asserted moral independence whether or not we actually possess it. By virtue of the second we have asserted metaphysical independence as well. If on the other hand we decide to let God determine our relation to him, that decision must be ex hypothesi already the result of God's work in us, otherwise we were the originators of divine act. But that God shall decide what is the relation between Him and us means that he shall decide for both the moral and the metaphysical sphere. For we, when we decided to let God determine, recognized that we ourselves through sin were totally unable to come to an adequate conception of our moral relation to him. But if God determines the moral relationship it means that he is absolute, that he is infinite, and the only standard of all existence and thus also the only determiner of our metaphysical relation to him. This implies that the moral is based upon the metaphysical though our argument does not proceed that way, for that question must be considered upon its own merits and cannot here be taken for granted. Here we would argue that once having accepted the fact of sin we cannot assume a halfway position and determine further for ourselves what our metaphysical relation to him shall be. And all this then means total dependence in the metaphysical and moral spheres upon God. As soon as we fairly begin to consider the question of our relation to God at all we have already decided it in its fundamental aspect.
Since we know that we have been taken by the Spirit of God from out of the mire of our own judgment we take the stand upon revelation alone, fully conscious of the fact that in so doing we have given up the claim to any moral or metaphysical independence. We have justified our position on the basis of philosophy as far as it can be justified. Our apologetic has been negative, and as far as it has been negative, if not misrepresented, it must also be coercive for those that assume a different position form ours. We do not contend that the positive argument must therefore also be convincing. That would be a contradiction of our own position. If you have lost a child and I have found one, it does not therefore mean that the child I have found is your child. With this illustration Dr. A Kuyper makes the position clear which we, following him, have presented. It is exactly our position that the absolute alone can furnish the positive apologetic. He must draw us out of darkness to his marvelous light. For even if we should agree that reason needs a corrective, what guarantee is there that Scripture furnishes the same and that it is not a mere result of imagination?
The παλιγγενεσια splits mankind in two and consequently also the consciousness of mankind. Not at all as though the powers and the faculties of the soul were changed, as though the one could now think more logically than the other, as though creation were changed by recreation. "Het terrein der palingenesie is geen nieuw geschapen erf maar vrucht van herschepping, zoodat het natuurlijk leven er in gesubsumeerd is, en dus ook het natuurlijke bewustzijn, d. w. z. die krachten eigen schappen en bestaansregelen, waaraan het menschlijk bewustzijn, uit zijn natuur, krachtens de schepping onderworpen is." 39 The antithesis is therefore not physical as has often been held by mystics of every description. On the contrary, regeneration builds on the only sound psychological basis, namely that of faith. Faith is here taken not as saving faith but as the general formal action of our consciousness that precedes and makes possible all science. Faith and science are therefore no opposites; logic never gives certainty. There must be faith at the basis of logic. Faith is the basis of all perception; the subject must have faith in the reality of the objects of perception; faith is the only link between phenomenon and noumenon. So also with our further mental activity. We must accept axioms by faith or we cannot even begin to reason. 40 What is more, we must have faith in the reality of self-consciousness. If it should be objected that the entire constitutive activity of the mind is accounted for on the stream of consciousness theory of the soul which sees in the last thought a synthetic "psychic integer" which as a full-grown son springs from the forehead of his father, the previous thought, proudly bearing the title deed, it is replied with John Stuart Mill that we are then placed before a paradox. We must either believe that the self-consciousness is distinct from the phenomena, or consciousness, or we have to accept the paradox that a series of perceptions can be conscious of itself as a series. 41 Thus we believe that in self-consciousness we are dealing with a noumenon, with a reality immovable previous to all ratiocination. In self-consciousness, then, our own existence is revealed to us, an act of God, and we accept it by faith, an act of God. This fundamental fact of self-consciousness as revealed to us again in turn implies our faith in reality beyond ourselves. In spite of the Criticism and even because of it we build the firmer on the faith given in consciousness that the Ding an sich operates upon our spiritual apperception within us, in a mysterious fashion beneath the threshold of consciousness. 42 Thus by the very power of faith which is presupposed as a basis of all knowledge we are again driven to the conception of an infinite self-revealing God, and absolutely dependent, finite creatures.
Moreover, since the antithesis is not physical there may be territories in the field of science in which the unregenerate and the regenerate can cooperate, as e.g. in the collection of sense material, in the somatic aspects of the psychological science, and thirdly, in formal logic for the laws of reason were not abrogated by sin. But when it comes to an interpretation of facts there must be a parting of the ways, for then he that has fixed his foot on the basis of the παλιγγενεσια is guided by supernatural revelation because he recognizes that he himself has no light. He still has the machinery of perception and thought, but God must originate and guide its motion.
It would seem that an apologetic for Theism as has been presented is the only thorough and tenable one. Any apologetic for Theism that would base its claim to acceptance upon the positive coercive power of its arguments even for the unregenerated consciousness is foredoomed to failure, defeats its own purpose, and denies its principle. It is foredoomed to failure because it presupposes receptability in the unregenerate consciousness which only a Divine act can give. It defeats its own purpose of bringing others to its viewpoint; rather the drowning man is dragging him down. It denies its own principle which is that of the principium speciale, the nature of which is that it cannot be subjected to the judgment of the principium generale. Only when Biblical Theism builds firmly and exclusively upon this principium speciale can it expect to give a reasoned account of its faith and build up a metaphysic and system of theology that will do justice to both infinite and finite, and serve as a satisfactory solution for the problem of the will.
It is not necessary to exhaust every ounce of logic to show that the theistic arguments should be convincing for every unprejudiced mind. It seems that this is Professor Robert Flint's mistake in his great work on Theism. He forgets that every man is prejudiced. Dr. Bavinck gives these theistic arguments an entirely different treatment. Take e.g. the argument from causality. Professor Flint thinks that it must necessarily lead us back to the idea of a personal absolute cause of the world, because we cannot rest in an infinite regress. "Reason, if honest and consistence cannot in its pursuit of causes stop short of the rational will. That alone answers to and satisfies its idea of causes." In spite of such an assertion Dr. Bavinck maintains that all we can establish from the idea of cause is that the world needs a cause. "Wie uit de wereld tot eene oorzaak besluit, welke zelve ook eene oorzaak behoeft, heeft aan de logische kracht van dit bewijs genoeg gedaan." 43 A finite effect can lead to a finite cause and we may regress ad infinitum into a vicious infinite, but who gives us the right to span the gulf between the finite and the infinite, and then to a personal God? Our idea of causation is not satisfied with less, says Professor Flint, but is this not perhaps already due to our theistic consciousness? To be sure, we cannot rest in a vicious infinite; some absolute is presupposed and only on its presupposition can the cosmological proof lead us to an absolute cause. But whether this cause is transcendent as well as immanent, personal as well as impersonal, conscious or unconscious, cannot be determined by the argument.
The only tenable position accordingly is, as we have found, to take our Archimedian που στω in the Action of the Spirit on the heart of man whereby he is brought into a new and living contact with truth. So also Dr. Charles Hodge, though often appealing to the common consciousness of man in presenting the reasonableness of faith in Christianity, maintains that in the last analysis the truth of God is the basis of all knowledge. "That our senses do no deceive us, that consciousness is trustworthy in what it teaches, that anything is what it appears to us to be, that our existence is not a delusive dream, has no other foundation than the truth of God. In this sense all knowledge is grounded on faith, i.e. the belief that God is true." 44
Building upon the results worked out by these men, Dr. Valentine Hepp has elaborated his work on the Holy Spirit. The Testimonium Spiritus Sancti generale, which he distinguishes from the speciale, is to him the last ground of trustworthiness of our human nature. "Het testimonium generale is die onmiddelijke en onwederstandelijke werking van den Heilgien Geist waarin Hij tot en in den mensch getuigenis geeft aan de waarheid in haar eentrum en daardoor in ieder mensch een onomstootelijke zekerheid doet geboren worden. Of philosophisch gesproken: het testimonium generale is de laatste zekerheidsgrond onzer kennis." 45 We are dependent for knowledge of self and God upon the Holy Spirit not only in the soteriological sphere but also in the natural. In conjunction with this, Dr. Hepp intimates that the knowledge of the truth of the content of Scripture is based on the testimonium speciale of the Spirit and this special testimony works on the basis laid by the testimonium generale. This is the logical consequence of the view of Reformed theology that creation is not abrogated by regeneration or recreation but is subsumed under it, or rather that regeneration builds upon the basis of creation.
Now we have stated and justified from a philosophical viewpoint the metaphysic and epistemology upon which alone, it would seem, an adequate conception of the relation between God and man or more specifically of the will is possible. The position has been called transcendental Realism and we believe it to be "theism come to its own." To give a more explicit statement of this position, with direct reference to the problem in its more technical significance, to justify it as the only one true to the very concept of Theism and Revelation, and to trace how the history of Christian thought has wrestled through the ages to come to a clear statement of Biblical truth upon the question in hand remains for the remainder of this essay.
Notebook 2: Christian Theology Of The Will
Fundamentally anyone that has placed himself or who has been placed upon the basis of the principium speciale as before defined, will try to do justice to all the elements in revelation. He makes God's revelation the standard and adjusts his concept of liberty accordingly. On the other hand anyone standing on the basis of the principium generale will in the ultimate sense make himself the standard, will not without reservation submit himself to revelation and thus either come to determinism, whether it be pantheistic, materialistic or rationalistic, or to libertarianism according as his views of psychology, epistemology and metaphysics may vary. All the forms of liberty that we have discussed so far were of that nature. But there is a large class of those who profess to recognize the authority and ultimacy of the special revelation, but that have not fully grasped the absolute nature of the antithesis between the two principia and who thus also want to maintain the authority of the principium generale. Dr. E. Beecher in his Conflict of Ages presents an admirable example of such a position. He recognizes the authority of Scripture, but alongside of them maintains as an equal standard the universal principles of justice etc., inherent in the common consciousness of man. We do not contend that there are no such principles, but only that it is unscientific thus to combine two principles without giving ample justification for doing so. He has indeed appealed to the authority of previous scholars but has not asked himself what exactly men like Charles Hodge etc. mean by these general principles. Anyone making these general principles of the consciousness of man a court of appeal cannot justly do so till he has subjected the present state of consciousness to a searching scrutiny and established its foundation capacity. This search he cannot carry on except by using Scripture as a standard and this already implies that these principles must at any rate be subordinate to Scripture. Then he will have to ascertain the epistemological influence of sin, and how far common grace has made it possible for us to base argumentation on this sin-affected foundation.
There is here a very subtle enemy that seeks to entrench itself within the theistic camp. Failure to distinguish clearly at this point and establish the exact bearing power of the common consciousness of man almost always tends to fraternization with the principium generale. Surreptitiously a new head arises from the serpent of rationalism, and there results confusion worse confounded. If this is not the case it is a happy inconsistency. The views of God and man and of their relations to one another, i.e. the views of the will, vary as they consistently or inconsistently keep out this rationalistic motif.
Even the very order in which the various loci of systematic theology are to be treated is controlled by the extent that this absolute character of the distinction between the two principia is recognized. Luther, for example, though claiming to base himself firmly on the Word, yet took anthropology as the starting point of his system and could therefore never do full justice to the theistic concept. It was inevitable that this false starting point of Luther would later wreak itself in the further development of the Lutheran system.
When we aim to place ourselves firmly on the principium speciale, our investigation will have to be entirely inductive. We shall have to trace the argument from all angles and then follow that argument whithersoever it may lead us. If we should come to find an absolute determinism taught in the Scriptures we would have to submit, or if we should find libertarianism or anything else taught we shall have to submit. Even if our own logic should have to recognize and openly declare its own bankruptcy to comprehend all the threads of revelation, we shall have to trust to a logic that is higher than ours. And this is then the logical thing to do for logic, because if it did not do this it would be placing itself back upon the principium generale. If we shall find that there are two parallel lines leading us on to eternity which do not meet on this side of the grave, we shall have to believe that they meet beyond. Scrupulously even, will we have to be on guard then, against subjecting one line of revelation to the other.
But you say that our search can no longer be purely inductive. Previously it has been stated that before we can fairly state the problem we have already taken position. This is true. Our position on the basis of the principium speciale demands that we make God the standard and we can never come to a strictly libertarian point of view. But our very position is given us by revelation, a revelation of the nature of ourselves which the Holy Spirit gives us by the very act of regeneration. Whether the Holy Spirit does this in conjunction with or in independence of the Scriptures may for the time being be left out of consideration. So much is clear that we could never have assumed our position upon the basis of the principium speciale or at least we could not work consciously upon that basis if we had no revelation of God about ourselves. This contention is not detrimental to the idea that the work of the Spirit within the individual is no objective revelation; it is the application of objective revelation and is thus a subjective revelation based upon the objective.
Moreover, our position so far has been entirely general. In the nature of the case we must begin with our own consciousness and because we have passed through the experience of sin and regeneration we must turn to post-redemptive special revelation and see what God there reveals of himself and his relation to man even before the entrance of sin and also after it.
Then we shall further impartially have to ascertain whether the relation of our will to God, in the condition that we are now, is to be taken as the normal standard that God adopts for man or whether we have perhaps in Adam the true test case of the concept of the will, or whether there is a more general concept of the will underlying both and inherent in the nature of man of which both Adam's and ours are modifications. Now we believe with John L. Girardeau (The Will In its Theological Relations) that in Adam before the fall we deal with the original and real relation of God to man. The present condition after the entrance of sin is, to be sure, abnormal. Extreme Pelagianism even admits that Adam's example has a rather seducing influence and we are fortunate if the whirlpool does not drag us down. And if we conceive of Adam's posterity as it would be in case Adam had not fallen, their wills would not have been the same as Adam's; they would have been confirmed by grace. We have our choice then between viewing Adam's case as abnormal and not having any relation to ours, or viewing him as the only pure test case. We shall find our relation to God to be entirely independent of Adam because his was an abnormal case, or we shall find our relation to God exactly focused in Adam.
It will be our first task then, since we cannot accept the Pelagian position that we have no essential relation to Adam, to ascertain exactly what Adam's relation was to God.
Our method in doing this will be to apply the several conceptions of the will that have been held through the history of the Church whether with direct reference to Adam or to man in general, and see whether they fit Adam's case. Which of these conceptions moreover, if any, corresponds with the revelation of God concerning his own nature, attributes, and decrees, for that is our ultimate standard.
39 Abraham Kuyper, Encyclopaedie der Heilige Godgeleerdheid (Amsterdam, 1894), 2:541.
40 Anne Anema Calvinisme en Rechtwetenschap,Amsterdam: Kirchner, 1897, 32.
41 Herman Bavinck, Wijsbegeerte der Openbaring, 1909, 51.
42 Jan Woltjer, Ideèel en Reèel,Amsterdam: Wormser, 1896, 34.
43 Bavinck, Gereformeerde Dogmatiek, 2:61.
44 Hodge, Systematic Theology, 1:437.
45 Valentine Hepp, Testimonium Spiritus Sancti, 1914, 245.


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running "zombie"?
Neptune is a single-player modification for Half-Life 2, taking place entirely outside the mother game's universe. Set primarily onboard a mysterious and desolate cruise liner, floating in the middle of the Atlantic Ocean, Neptune allows the player to slowly unravel the dark and disturbing past of the ship as he/she explores its once-grand rooms, corridors, concert halls, restaurants, bars and maintenance areas. Taking influence from games such as System Shock 2, BioShock, Thief: Deadly Shadows and Silent Hill, Neptune is an atmospheric, narrative-driven, horror-based shooter; an exercise in videogame storytelling and tense level design. It is expected to be released in Q3 2009.
running "zombie"?
Not strictly a zomb, or even a typical flesh-ripping 'infected'. But yeah, we'll give you that. ;)
i would prefer slow zombies ... :(
I think people might be surprised with the enemies... they're really not 'zombies' in any conventional way except for perhaps the way they look. Expect something more in like with SS2 and BioShock's foes.
Crazy people? Who are really crazy in the head and kill anything that moves?
Well, zombies aren't always the flesh eating things known in pop-culture today, a zombie is more of a term to describe someone in deep hypnosis or someone with no control.
Or a common term used by Voodoo Priests that use a powder to make a subject faint and become clinically dead, but after a while, the person revives.
Zombification....the non-hollywood version.
Face of zombie is white :P
man from 1187 =D
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subset: commoncrawl


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text:
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Thank you to everyone who submitted to the very first One Big Book Launch. The submissions we received were of a really high quality, and we are really pleased to announce the names and titles of the 10 authors chosen for the event below.
Two Egmont titles, fiction from No Exit Press, and poetry/plays from the outstanding Sabrina Mahfouz, join five self-published titles, and New Adult fiction from an award-winning Cookery Writer in her 70s.
The mix of genres, target readership, and publishers in this line-up makes for a really eclectic and exciting evening of celebrations! Tickets are still available from the Free Word Centre, here. What's more, we are really excited to see titles from big name publishers such as Egmont, Bloomsbury, and No Exit Press join self-published titles to share celebrations and publicity. Books were chosen for this event on quality of writing and marketability, and we are proud to see three CompletelyNovel authors on this list with them.
Have a great book you'd like to publish? Click here to find out how!
One Big Book Launch Confirmed Authors, 2014
Catherine Bruton – I Predict A Riot
Contemporary fiction. Egmont.
Gritty, contemporary, hard-hitting, heart-breaking fiction inspired by the 2011 riots.
It's been a year since everything happened, but I still have bad dreams. Dreams of me and Tokes and Little Pea, racing through burning streets on the night the city was in flames …
Welcome to Coronation Road – a kaleidoscope of clashing cultures and parallel lives. There's Maggie and her politician mum in their big house. There's Tokes and his mum in a tiny bedsit, running from trouble. And there's the ruthless Starfish gang, breeding fear throughout the neighbourhood.
Amateur film-maker Maggie prefers to watch life through the lens of her camera. In Tokes, she finds a great subject for her new film. And when violence erupts, led by the Starfish gang, Maggie has the perfect backdrop. But as the world explodes around her, Maggie can't hide behind the lens any more…
Explosive drama, perfect for fans of Meg Rosoff and Annabel Pitcher.
J. Paul Henderson – Last Bus to Coffeeville
Commercial literary fiction. No Exit Press.
A poignant, uplifting and charming story that promises to be one of the break-out books of 2014. It won't let you down…
For fans of 'The Unlikely Pilgrimage of Harold Fry' and 'The Hundred Year Old Man Who Climbed Out of the Window and Disappeared'.
Nancy Skidmore has Alzheimer's and her oldest friend Eugene Chaney III once more a purpose in life – to end hers. When the moment for Gene to take Nancy to her desired death in Coffeeville arrives, she is unexpectedly admitted to the secure unit of a nursing home and he calls upon his two remaining friends to help break her out: one a disgraced weatherman in the throes of a midlife crisis and the other officially dead for forty years.
On a tour bus once stolen from Paul McCartney, Nancy and Gene are joined by a colourful cast of characters as they career through a landscape of war, communism, religion and racism and along the way discover the true meaning of love, family, and, most important of all, friendship.
Charming, uplifting and profoundly moving, 'Last Bus to Coffeeville' is a chronicle of lives that have jumped the tracks; a tale of endings and new beginnings; a funny story about sad things.
Atulya K Bingham – Ayşe's Trail
Literary fiction based in Turkey. CompletelyNovel title.
Ayşe, a 38-year-old mother from Istanbul, decides to tackle the Lycian Way in southern Turkey. Based on the true story of Ayşe Metin.
Ayşe, a 38-year-old mother from Istanbul, decides to tackle the Lycian Way in southern Turkey. She has never camped alone before. As she strikes out into Lycia's ancient forests, she is on a quest to leave behind the past. But the Lycian Way is steeped in memories. Unknown to Ayşe, as she clambers over the precipices of the Mediterranean coast and through its lost cities, she is walking in someone else's footsteps. 2500 years earlier, when Lycia was an independent state and worshipped the Goddess Leto, the Persian general Harpagos was stomping along the very same road in a bid to take over the ancient world. As Ayşe continues her lone, meandering odyssey of self-discovery, her troubled youth in Istanbul re-emerges. But she's not the only one to remember. Unknown to most, the legends of old still haunt Lycia. Her stories call out to the walkers and shepherds as they climb over her timeless skin. Because time is not what we think it is. The past is never over. And a map can only ever tell so much of what a trail is all about.
Based on the true story of Ayşe Metin.
Sabrina Mahfouz – The Clean Collection
Poetry, plays. Bloomsbury Methuen Drama.
A dynamic collection of three of Sabrina Mahfouz's pieces for the theatre, published alongside a selection of her poetry.
Zainab, Chloe and Katya, London's best 'clean' criminals and perpetrators of victimless crime, are forced together in an unlikely trio. This feisty trio soon become the unlikely action heroes of an adventure left to men. A short play commissioned by the Traverse Theatre, 2012, Clean was part of the A Play, A Pie & A Pint Season at Òran Mor, Glasgow and The Traverse Theatre, Edinburgh.
Dry Ice
A critically acclaimed solo show about a young stripper, which was produced at by the Underbelly (Edinburgh) and the Bush Theatre (London), and directed by David Schwimmer. It played at the Contact (Manchester), the Southbank Centre (London) and the Bush (London) as part of Madani Youni's debut season in 2012.
One Hour Only
An 'upmarket brothel'. It's Forensic Biology student Marley's first night at her new job and AJ, twenty-one, good-looking and intelligent, is her unexpected first client. One Hour Only formed part of the Old Vic New Voices' first ever Edinburgh Season at the Underbelly in association with IdeasTap.
Tracy Elner – Blue Eye
Thriller fiction. CompletelyNovel title.
Set against the backdrop of the world's oldest lake, Blue Eye is a fast moving conspiracy thriller addressing some of the burning issues of our time and a gripping journey of transformation for its hero, Scott Carty.
London-based derivatives trader, Scott Carty, doesn't give any weight to the inexplicable dreams he's been having. That is until his mercurial boss, Arthur D'albo, summarily dispatches him to an energy conference in Kazakhstan along with a curious instruction to deliver a locked briefcase.
Soon enough, the dreams' premonitions begin to resonate with an alarming clarity as he becomes entangled with the beautiful Lena Isotova and uncovers D'albo's sinister business, lubricating the wheels of a covert, Cold War energy technology.
It's a secret that carries a deadly price and, targeted by ruthless killers, he's forced to flee with Lena's mysterious friends into the Siberian forest around the shores of Lake Baikal. There, he is awakened to the mystical nature of reality and the staggering truth about the technology's potential threat to the global economic order.
Meanwhile, back in London, Carty is a wanted man but everyone believes he's been killed in Russia; everyone but the intelligence agencies. What do they really know about this enigma and why is Carty's survival so important to them?
Simon Fairbanks – The Sheriff
Fantasy novella. Self-Published.
A fantasy novella popular with young adult fantasy fans, although the content is suitable for all ages, written by Fairbanks, a respected member of the Birmingham Writers' Group since 2011.
The Sheriffs wander the clouds to keep the peace across Nephos. Sheriff Denebola is recruited by young Toby to help rid his village of a winged demon. The demon has tormented the people of Angel's Keep every night for the past week so Denebola vows to capture the creature. However, the demon is not the only shadow cast over Angel's Keep. There is the strict priest, Father Osmond, who detests all magic. There is Gideon, a man with wings, claiming to be an angel sent by the Lord. And there is also the matter of the Red Witch, who threatened the village five years before the demon's arrival. Denebola soon finds himself caught up in a mystery where angels, demons, heroes and villains are not all that they seem.
Angie Morgan – Shouty Arthur
Large format children's picture book. Egmont.
This hilarious, energetic and quirky book is the first in a series from Angie Morgan. It will have parents and children alike laughing from start to finish.
"We haven't see any wildlife yet, Edith!" shouted Arthur.
"That's because you're too shouty," said Edith. "You promised to be quiet."
"Being quiet is very hard," said Arthur.
Shouty Arthur is the LOUDEST and MOST SHOUTIEST boy alive. He wants to go wildlife watching with his sister Edith, but he can't understand why the animals are nowhere to be seen.
This hilarious, energetic and quirky book is the first in a series from Angie Morgan. It will have parents and children alike laughing from start to finish.
David Zen – Jiāo Yì (交易): The Deal
Business suspense fiction. CompletelyNovel title.
With high-stakes investment, and the perils and victories of entrepreneurship, this début novel explores the risks of corruption in cross-border investment deals, in a changing modern China.
It is 2009, the depths of the global financial crisis. Jasmine Liu and April Wang are on opposite sides of an investment deal which they know simply as jiāo yì (交易), "the deal". Jasmine is from China, but working in Los Angeles after business school. April is from a Chinese family but has grown up in the United States, and is working in Shanghai for a Property Company, owned by her uncle.
Julia Johnston – If Everyone Knew Every Plant And Tree
YA crossover fiction. Self-Published.
A beautifully written, emotionally-charged and yet funny crossover novel by exciting new author, Julia Johnston. "Rarely does a writer depict characters, capture teenage banter, and create mood so brilliantly."
Ollie is drowning. No one notices.
Oliver Campbell, fourteen, fanciful and funny in equal measure, struggles to unravel the knots of emotion when his little sister, Lily, falls gravely ill with a mysterious disease. Irritating and puzzling to his two older half-brothers, neglected by his self-absorbed mum and dad, and unfalleninlovewith by Poppy Teasdale, he longs to be something more than invisible.
Quirky Kamal doesn't think it's weird that Ollie, his best friend, is fascinated by words and plants; he knows what it's like to be different and to be bullied; he coaches him on love, and how to clinch his dream-girl; he tickles him with his high-falutin language and aspirations; he impresses him with his fortitude despite a tragic past; he is there when his life takes a terrible turn; he is loyal to the end.
Ollie's two special people throw him life jackets, but will they be enough to save him…?
Judy Jackson – Sextet
A contemporary story of music and deceit. Marsons Books.
Respected food writer, Judy Jackson, at over seventy, has written a book for twenty-somethings. Sextet explores the fallout from a brief extramarital affair and shows how it has shattered six people's lives.
Two strangers meet in a hospital, unaware that their lives are inextricably linked. Tom Fielding is waiting for news of his wife, the victim of a road accident. Joseph Maggiore is silent, blaming himself for the crisis that engulfed his world and led to his wife lying unconscious in Intensive Care. When tragedy strikes, both men are left to confront painful reality. Tom evaluates his marriage to the fragile and elegant Sophie. Joseph has neglected Carla in his pursuit of fame as a concert pianist.
As their lives unravel, Tom seeks justice from the authorities, and Joseph learns a truth that rocks the foundation of his being. Joseph's agent Richard and an innocent child are enmeshed in the fallout from unforeseen discoveries.
Sextet follows Joseph and Tom on a journey through grief and recovery. The drama of betrayal and deception is played out against a background of piano music and hotel bedrooms. The facade of harmony is torn away and from six shattered lives, hope emerges.
Celebrate with us at the One Big Book Launch, at The Free Word Centre on 30th April 2014. Click here to reserve your ticket.
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Perfomance. Visual Arts. Film. Classic Arts Showcase is designed to inspire new audiences by showcasing video clips of the arts.
A national, daily, independent, award-winning news program hosted by journalists Amy Goodman and Juan Gonzalez.
Coverage of NASA missions and events, plus documentaries, archival and other special programming.
Sirk TV now syndicates award winning first-run syndicated television and film programming to broadcast television stations across the nation, both on cable and at colleges. They feature variety shows, feature films, documentaries, reality shows, interstitials, celebrity interviews, and more. More information can be found on their website, www.sirktv.com.


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Weekend Not As Planned
This entry was originally intended to describe our fun weekend: Dim Sum in Portland, Corinne's woodworking project, and snowboarding. But Mother Nature apparently thought she wasn't getting enough coverage in this blog...
But I'm getting ahead of myself. Our friend Rat invited us to dim-sum in Portland to celebrate the coming Year of the Rat. Corinne had also coordinated with our friend Ken to use his woodworking shop (and his expertise) for a cedar shelf project she had been planning. Since he lives outside of Portland, we planned for a Saturday in the city to accomplish both tasks, then return home to go snowboarding the following day.
The plan started to break down almost immediately. The weather forecast had called for some heavy snow conditions and icy roads, and we didn't even make it to our first destination without being stopped behind an accident. After about a half hour delay, we made it to the restaurant safely and enjoyed an exotic array of Asian dishes. But by the end of our meal, I-84 - the main road east/west between Portland and Hood River - had been closed with no estimate as to when it would reopen. Since we already had the afternoon scheduled with Ken, we headed back to his shop and began the project.
When we talked to the folks who drove home Saturday night, we found out that a trip that would normally take <1 hour took them 3 hours that night, and that the road was in pretty bad shape. I think we made the right choice.
Several hours later, we had the driveway cleared and were able to get the car into the garage. When I went to take the chains off, I noticed that one of the front tires was flat. I began the process of putting on the spare when I noticed that BOTH of the front tires were flat! After some choice words, I made a closer inspection and realized that the chains had rubbed up against the valve covers and loosened them just enough to let air out. I reinflated the tires and everything was fine.
That's a lot of snow. Thank goodness this didn't fall when we were in Florida!
- Mike (& Corinne)


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For too long the Indian Companies Act, 1956 governed the corporate culture and regulatory regime for companies operating in India. The need to enact a contemporary law was long felt but for many decades this need was not transformed into a modern corporate law of India. Finally, the Indian Companies Act, 2013 (PDF) was enacted and its enforcement was planned to be made in a phased manner.
The Ministry of Corporate Affairs (MCA) has already notified some sections and rules of the Indian Companies Act, 2013. Interested stakeholders may see the consolidated notifications of Indian Companies Act, 2013 and the corresponding rules for a better and detailed insight. The companies and individuals associated with them are required to comply with the new compliance and regulatory requirements with effect from 01-04-2014.
We at Perry4Law believe that this is a big challenge for the companies and these individuals as most of these compliance requirements are new and require non traditional approach. It is not easy to migrate from the 1956 Act to the 2013 Act so easily. The times have changed especially due to the techno legal compliances requirements that Indian companies cannot ignored anymore. These include cyber law due diligence (PDF) and cyber security due diligence.
Corporate frauds investigation in India would also increase as the Serious Frauds Investigation office (SFIO) has been given wide powers under the 2013 Act. MCA has also issued some Rules under Chapter XIV of Indian Companies Act, 2013 pertaining to Inspection, Inquiry and Investigation by Indian Authorities and SFIO. Perry4Law has also provided its suggestions (PDF) on these rules.
Corporate espionage cases would require the companies to manage complicated e-discovery and cyber forensics compliances issues in the future. For instance, Target Corporation is facing numerous litigations in different jurisdictions due to cyber breach that it failed to address properly. International legal issues of cyber attacks would also be required to be kept in mind by Indian companies under the new corporate environment. Clearly the cyber and technology law compliances in India would be a big challenge for Indian companies to manage as that cannot be ignored by Indian companies anymore.
With the present techno legal framework and its non compliance by Indian and foreign companies, the cyber litigations against foreign websites would increase in India in the near future. Even the foreign investors in e-commerce and technology ventures of India are required to follow cyber law due diligence requirements. Very soon mandatory cyber security breach notifications would be enforced in India as well. Further, cyber security breaches in India would also raise complicated cyber security issues for the companies as most of them are not complying with techno legal requirements of Indian laws and regulations.


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Easy Animal Home » Latest News » Brits can't stop thinking of pets while on holiday, study reveals
Brits can't stop thinking of pets while on holiday, study reveals
Posted by: Richard Towey Date: 25/02/2013 Category: Latest News
New research indicates that despite being thousands of miles away, Brits can't stop thinking about their pets whilst on holiday.
A poll of 2,000 holidaymakers from Thomas Cook reveals just how much British pet owners think about their beloved companions while they're supposed to be escaping from life at home.
The study found that one in three owners send an email to someone at home to check how their pet is coping without their adopted family.
While some people seemed quite content with just knowing their friends were getting on alright, words of assurance just weren't enough for some. One in 20 even admitted to Skyping or speaking down the phone to their pet whilst on holiday, with one in ten taking a photo of their pet with them.
The results also suggested that stacks of dog cages might be making their way into the plane cargo. A total of 13 per cent allowed their pets to come with them, while iwantsun.co.uk estimates that 100,000 British pets have their own passport.
Finally, one in ten may not have allowed their pets on board but felt guilty enough to bring them back a present. According to a report on pet prezzies from lancasteronline.com, dog t-shirts, ponchos, scarves and chew toys are considered the most popular souvenirs.


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Animated Explainer Videos
Sometimes, something just can't be conveyed in words. At least not clearly. At other times, you just don't have the time or resources to do a great-quality live video. (Or, maybe you just don't want to be on camera!) That's where our animated explainer videos come in. Check out a sample! –
Check out our Portfolio for a few more samples of our explainers!
They say a picture is worth 1,000 words – An explainer video is worth a million. Get Started Below –


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I don't believe anyone's life story or recollections can be of any use in understanding how an artist creates. For instance, a certain composer having pneumonia tells me nothing about how or why they mold various sounds together. Or does it?
Update Required To play the media you will need to either update your browser to a recent version or update your Flash plugin.


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It is still controversial whether there are synergistic effects among different non-pharmacological interventions used in the treatment of hypertension.
To evaluate the effect of aerobic exercise, oral supplementation of potassium and their combination on blood pressure, glucose metabolism, urinary albumin excretion and glomerular morphology in spontaneously hypertensive rats (SHR).
SHR were divided into groups: Control Group (SHR; standard diet and sedentary, n = 10), Exercise Group (SHR + E; trained on a treadmill, standard diet, n = 10), Potassium Group (SHR + K; sedentary, potassium supplementation, n = 10) and Group Exercise + Potassium (SHR + E + K, exercise, potassium supplementation n = 10). Weekly, body weight (BW) and tail blood pressure (TAP) were measured. At the end of 16 weeks, a Oral Glucose Tolerance Test was performed. Albuminuria was determined in the baseline period, at 8th and at 16th week. After sacrifice, the analysis of glomerular sclerosis index and visceral fat weight was performed.
The TAP and BW did not change significantly. There was improvement in insulin sensitivity in SHR + E and SHR + K, but not in SHR + E + K. At week 16, albuminuria in all groups was significantly lower than the SHR control. The glomerular sclerosis index and visceral fat content were also significantly lower in all groups compared to control.
An oral supplementation of potassium and exercise led to an improvement in glucose metabolism, in albuminuria and glomerular morphology, however, the overlap of the treatments did not show synergism.
Keywords: albuminuria; exercise; hypertension; kidney glomerulus; potassium chloride; rats, inbred SHR;
Acute kidney injury (AKI) in patients receiving cisplatin is common, therefore the evaluation of renal function in patients on use of nephrotoxic drugs is fundamental.
To evaluate the incidence of AKI and the role of lipocalin associated to neutrophil gelatinase (NGAL) in the monitoring of renal function in patients with head and neck cancer (HNC) who received cisplatin.
We prospectively studied 50 patients with HNC treated with three sessions of cisplatin. Blood and urine were collected 24 hours before cisplatin, 24 hours after infusion, 48 hours after each application and 35 days after the end of treatment (urine NGAL, C-reactive protein, creatinine, glomerular filtration rate, plasma lactate dehydrogenase and magnesium).
AKI was observed in 78% of patients. There was increase in creatinine, and decrease in GFR after each cycle of cisplatin, and increased urine NGAL. Positive association was observed between the levels of NGAL, creatinine and C-reactive protein. It was observed an increase in creatinine, NGAL, C-reactive protein and decreased GFR in AKI patients compared to patients without AKI.
AKI was noted in 78% of patients with HNC treated with cisplatin and showed the correlation of NGAL with creatinine and GFR in demonstrating renal injury. NGAL levels may be elevated compared to baseline levels, even before the use of cisplatin.
Keywords: acute kidney injury; cisplatin; lipocalins;
Experimental studies have suggested that indoxyl sulfate (IS), a protein-bound uremic toxin, may be involved in the development of renal osteodystrophy.
evaluate the association between IS levels and biochemical parameters related to mineral metabolism and bone histomorphometry in a cohort of pre-dialysis chronic kidney disease (CKD) patients.
This is a post-hoc analysis of an observational study evaluating the association between coronary calcification and bone biopsy findings in 49 patients (age: 52 ± 10 years; 67% male; estimated glomerular filtration rate: 36 ± 17 ml/min). Serum levels of IS were measured.
Patients at CKD stages 2 and 3 presented remarkably low bone formation rate. Patients at CKD stages 4 and 5 presented significantly higher osteoid volume, osteoblast and osteoclast surface, bone fibrosis volume and bone formation rate and a lower mineralization lag time than CKD stage 2 and 3 patients. We observed a positive association between IS levels on one hand and the bone formation rate, osteoid volume, osteoblast surface and bone fibrosis volume on the other. Multivariate regression models confirmed that the associations between IS levels and osteoblast surface and bone fibrosis volume were both independent of demographic and biochemical characteristics of the study population. A similar trend was observed for the bone formation rate.
Our findings demonstrated that IS is positively associated with bone formation rate in pre-dialysis CKD patients.
Keywords: indoxil sulfato; insuficiência renal crônica; osteodistrofia renal; uremia;
Chronic kidney disease (CKD) affects all age groups, and its prevalence has increased during recent years. CKD is divided into six stages, according to the renal function of patients: 1. Normal renal function without kidney damage; 2. Kidney damage with normal renal function; 3. Mild renal insufficiency; 4. Moderate renal insufficiency or lab tests failure; 5. Severe renal insufficiency or clinical failure; 6. End stage of chronic renal failure.
This study was intended to assess renal function in elderly patients and identifying the presence of factors associated with those changes.
A cross-sectional population-based study was performed. Elderly patients were surveyed between September 2010 and May 2011. Kidney function was assessed by determining of serum creatinine, and estimation of the glomerular filtration rate by the CKD-EPI equation.
In all, 822 elderly were surveyed; 61.6% were women; 92.2% were Causasian; and
most (61.0%) were aged between 60 and 69 years. With regard to the glomerular
filtration rate, 26.2% had a normal rate; 60.2% showed a slight decrease; 13.0% a
moderate decrease; 0.5% severe kidney function decline; and 0.1% extreme fall.
Increasing age was associated with kidney damage by decreased glomerular
filtration rate (
This study found that the great majority of the surveyed elderly had some mild kidney damage, and 13.6% showed moderate to severe dysfunction.
Keywords: aged; creatinine; glomerular filtration rate; kidney function tests; renal insufficiency;
Chronic kidney disease (CKD) has been identified in an increasing number of patients and among its consequences is the anemia.
To verify the occurrence of anemia in patients with CKD undergoing hemodialysis at a Hospital in the South Region, Brazil, as well as their kidney profile and iron profile.
It was performed a retrospective, descriptive and analytical study. It was analyzed 45 patient records with results from the beginning of the hemodialysis treatment until nine months later.
Over 50.0% of the patients had hypertension and diabetes and 68.8% were male. The
anemia was present in 97.8% of the patients and treated with erythropoietin and/or
iron. In the evaluated period occurred increase in median hemoglobin levels
After the Introduction of treatment for anemia occurred increased plasma levels of hemoglobin and clinical improvement, even though not having a complete normalization of these levels.
Keywords: anemia; creatinine; erythropoietin; renal insufficiency, chronic; urea;
Cardiovascular diseases (CVDs) are the leading cause of death in terminal patients with chronic kidney failure (CKF). Diverse risk factors are involved in the pathogenesis, and are classified as traditional, which affect the general population; and non-traditional, which are peculiar to patients with CKF. Secondary hyperparathyroidism, a non-traditional and common factor in CKF, can cause an increased rate of bone absorption with mobilization of calcium and phosphorus. If the product of calcium x phosphorus is increased, the solubility of this ionic pair may be exceeded and deposition of calcium phosphate in cardiac and vascular tissues occur (called metastatic calcification).
To verify eventual relationship between the thickness of the common carotid artery and the levels of PTH in patients with CKF.
Evaluations by Doppler ultrasonography were performed to measure the width of the carotid artery wall and to search for possible correlations between different values of PTH serum levels, mineral disturbances and traditional risk factors in the carotid changes found in individuals with dialytic CKF and secondary hyperparathyroidism.
Differences in the cholesterol level and age were observed in patients with
signals of arterial calcification. A significant relationship was also observed
between the PTH serum levels and the carotid artery wall thickness (r = 0.31,
Data from this study show the possible concomitance of traditional factors and factors related to CKF in the genesis of CVDs in uremia.
Keywords: carotid artery, common; heart diseases; hyperparathyroidism, secondary; kidney failure, chronic;
Chronic renal failure is a disease which prevalence has been increasing in Brazil. Hemodialysis is their primary therapeutic modality and arterio-venous fistula their preferential access. Nevertheless, many patients require the use of double-lumen catheters, either as permanent or temporary access. Vascular complications related to this procedure may occur, and their best method of non-invasive analysis is ultrasound analysis.
To analyze the complications by the use of double-lumen catheter in patients with chronic kidney disease on hemodialysis, at "Santa Casa de Misericordia de Ponta Grossa" hospital, through eco-Doppler exam.
Observational research, analytical, case-control type, to obtain data we used TASY®, interview, physical exam and imaging (eco-Doppler).
None of the variables was significant isolated as a predictor of vascular impact in eco-Doppler, which detected changes in 31.25% of the cases. Physical exam showed poor accuracy compared to Doppler capacity to detect complications (K = -0.123).
We conclude that the vascular effects of the use of CDL are frequent (31.25%). Manifesting itself in the form of occlusions with/without recanalization and stenoses. This leads us to required a prior analysis of the insertion site with Doppler, in order to avoid unnecessary procedures and possible complications.
Keywords: catheters; hemodialysis units, hospital; kidney failure, chronic;
Patients with chronic kidney disease (CKD) who perform renal replacement therapy (RRT) are subject to a higher prevalence of mood disorders.
The aim of this study is to compare the prevalence of anxiety and depression in patients on hemodialysis (HD) and peritoneal dialysis (PD), taking into account comorbidities that may contribute to this.
The study was done in Ponta Grossa with CKD patients, using Beck Depression and Anxiety Inventory (BDI and BAI) and the Hospital Anxiety and Depression Scale (HADS).
We studied 155 patients, 128 in the HD group and 27 in PD. In the first, depression was found in 22.6% of patients in the BDI and 9.3% in HADS, and anxiety 25.7% in the BAI and 11.7% in the HADS. In the PD group, 29.6% of patients had depression in the BDI and 14.8% in HADS, and anxiety 11.1% in the BAI and none in HADS.
The hemodialysis or peritoneal dialysis did not influence the prevalence of anxiety and depression in patients with CKD.
Keywords: anxiety; depression; hemodialysis units, hospital; peritoneal dialysis; renal dialysis; renal insufficiency, chronic;
Evaluate the quality of life of kidney transplant recipients has been a way to determine the impact of transplantation in health care and subsequent treatment of chronic character.
To analyze the association between income, work and quality of life of kidney transplant recipients.
The sample consisted of 147 people, with an average of 74.3 months of realization of the transplantation. Data was collected using the following methods: socioeconomic assessment tool and the Medical Outcome Study 36 - Item Short - Form Health Survey, validated for use in Brazil. A bivariate analysis was performed using the Mann-Whitney's U test.
The average quality of life related to health for the physical component was 63.8 (SD = 29.4), and for the mental component, 65.6 (SD = 29.2). The bivariate analysis showed that the exercise of labor activity and family income higher than three minimum wages were significantly associated with a better quality of life.
Labor activities are significant for kidney transplant recipients and special attention must be given by the multidisciplinary team in the search for strategies that promote and encourage their maintenance and reintegration into the labor market.
Keywords: qualidade de vida; renda; trabalho; transplante de rim;
Kidney transplantation is performed in emergency conditions in a population with high perioperative risk. Instruments for risk assessment before transplantation in this population are scarce.
To develop a score with pretransplant variables to estimate the probability of success of kidney transplantation, defined as survival of the recipient and the graft with creatinine < 1.5 mg/dl at 6 months.
Analysis of variables of patients from a unique kidney transplantation center in São Paulo. Logistic regression was used to construct an equation with variables able to estimate the probability of success. Integer points were assigned to variables for score construction.
Of the 305 patients analyzed, 176 (57.7%) achieved success. Of the 23 variables identified by univariate analysis, 21 were included in the logistic regression model and 10 that remained independently associated with success, were used in the score. Four of these 10 variables were socioeconomic. It was great (area under the ROC curve 0.817) the power of discrimination between groups success and not success and adequate (Hosmer and Lemeshow = 0.672) the agreement between frequencies of the probabilities estimated by equation and frequencies of probabilities actual observed. There were correlation (0.982) between the estimated probability via the scoring system and the estimated probabilities via logistic regression.
Point score simplified risk stratification of transplant candidate according to their probability of success. Socioeconomic variables influence the success, demonstrating the need for creation of prognostic tools utilizing clinical and demographic variables of our population.
Keywords: kidney transplantation; measures of association; exposure; risk; outcome; odds ratio; risk factors;
Mineral bone disorder (MBD) is a common condition in chronic kidney disease (CKD) patients and causes significant morbidity and mortality. Data involving prevalence of alterations in bone histological patterns, impact of different treatments and its repercussion in outcomes, such as bone fractures, hospitalization, cardiovascular disease and mortality, are scarce. Data bank registry can be a valuable tool to understand epidemiological aspects of MBD CKD. The Brazilian Registry of Bone Biopsy (REBRABO) will be a national registry, coordinating by the Brazilian Society of Nephrology - Committee of MBD-CKD.
To describe REBRABO's design, elements of data and methodology.
Will be an online national observational and multicentric data registry divided in two phases (retrospective, 1st phase) and prospective (2nd phase), including information from bone tissue histomorphometric analysis and demographics, clinical and laboratorial data from CKD-MBD patients.
The REBRABO's first phase will explore data on demographics, clinical, laboratorial and bone histomorphometric analysis data from January/1986 to December/2013. The first Results are expected in early 2015.
Studies in the field of CKD-MBD are needed, particularly those analyzing its prevalence, associations between demographic, clinical, histological parameters, and major outcomes. The REBRABO will be a unique retrospective and prospective research platform including bone biopsy data in CKD-MBD patients.
Keywords: bone diseases; electronic health records; renal insufficiency, chronic;
Contrast-induced nephropathy is a common complication of radiographic procedures. Different measures have been used to avoid this damage, but the evidence is controversial. New investigations are required to clarify it. We investigated the efficacy and safety of sodium bicarbonate solution compared with sodium chloride solution to prevent contrast induced nephropathy in patients with or at risk of renal dysfunction.
A prospective, single-center, randomized clinical trial conducted from May 1, 2007 to February 8, 2008. Inpatients in a tertiary center, scheduled to undergo a procedure with the nonionic radiographic contrast agent iohexol. There were 220 patients with serum creatinine levels of at least 1.2 mg/dL (106.1 µmol/L) and/or type 2 diabetics, who were randomized to receive an infusion of sodium chloride (n = 113) or sodium bicarbonate (n = 107) before and after contrast dye administration. The intervention were "A" group received 1 ml/kg/hour of normal saline solution, starting 12 hours before and continuing 12 hours after iohexol contrast. "B" group received 3 ml/kg of sodium bicarbonate solution (150 mEq/L) one hour prior to procedure and then drip rate was decreased to 1 ml/kg/hour until 6 hours post procedure. Our main outcome measure was change in serum creatinine.
The mean creatinine value after the procedure was 1.26 mg/dL in the saline group
and 1.22 mg/dL in the bicarbonate group (mean difference: 0.036; CI 95%: -0.16 to
Our investigation showed that there were no differences between normal saline
solution (extended infusion)
Keywords: bicarbonato de sódio; lesão renal aguda; meios de contraste; solução salina;
Chronic kidney disease (CKD), considered by some authors as an epidemic of this century, relates directly to chronic diseases such diabetes (DM) and high blood pressure (HBP) and increase the life expectancy of the population.
The aim of this study was to delineate epidemiological profile of patients on hemodialysis (HD) in a Brazilian capital.
We conducted a cross-sectional study of a random sample of convenience, using a questionnaire in 245 patients between August 2011 and March 2012. All patients interviewed were in HD program in three Nephrology services at the Unified Health System (UHS) in João Pessoa.
Of the respondents, 61% were male, 66% were married and 44.5% were white. Approximately 50% were aged 40-59 years and 51% were living out of João Pessoa. The main etiologies were HBP (38%) and DM (13%). Main comorbidities were diabetic retinopathy (15.5%) and peripheral neuropathy (13.5%). Ninety-two percent reported an episode of hospitalization. Temporary vascular access was used in 100% of patients in first dialysis.
Results of this study indicate the importance of better monitoring of these pre-dialysis patients, which could reduce morbimortality.
Keywords: health services accessibility; kidney failure, chronic; renal dialysis;
The treatment offered to chronic kidney disease (CKD) patients before starting hemodialysis (HD) impacts prognosis.
We seek differences among incident HD patients according to the distance between home and the dialysis center.
We included 179 CKD patients undergoing HD. Patients were stratified in two
groups: "living near the dialysis center" (patients whose hometown was in cities
up to 100 km from the dialysis center) or as "living far from the dialysis center"
(patients whose hometown was more than 100 km from the dialysis center).
Socioeconomic status, laboratory results, awareness of CKD before starting HD,
consultation with nephrologist before the first HD session, and type of vascular
access when starting HD were compared between the two groups. Comparisons of
continuous and categorical variables were performed using Student's
Ninety (50.3%) patients were classified as "living near the dialysis center" and
89 (49.7%) as "living far from the dialysis center". Patients living near the
dialysis center were more likely to know about their condition of CKD than those
living far from the dialysis center, respectively 46.6%
There are potential advantages of CKD awareness, referral to nephrologists and starting HD through fistula among patients living near the dialysis center.
Keywords: cateteres; diálise renal; fístula arteriovenosa; insuficiência renal crônica; referência e consulta;
Acute kidney injury (AKI) has a high hospital incidence and is associated to significant morbidity and mortality. Sepsis, major surgery and low cardiac output are the main cause of AKI worldwide. In the majority of these situations, volume expansion is part of both prevention and therapeutic management, restoring peripheral perfusion and attenuating drug nephrotoxicity. Early and aggressive volume resuscitation in septic patients halts tissue ischemia and is associated with higher survival. However, a liberal fluid infusion strategy after six hours can cause fluid overload. Fluid overload has been associated with morbidity and mortality increase in critically ill patients. Herein, we present a review of the main studies that assessed the effects of net fluid balance/fluid overload on the morbidity and mortality of critically ill patients. We suggest that positive water balance may be used as a potential early biomarker of AKI in these patients.
Keywords: acute kidney injury; intensive care unit; mortality; water balance;
The diagnosis of urolithiasis during pregnancy is common, even though no additional measures are required in asymptomatic cases. Renal colic or complications of urinary lithiasis occur more frequently during the last months of pregnancy, and there are several particularities for the diagnosis and treatment of this subset of women. The present manuscript aim to review the current knowledge concerning this subject and present authors personal experience.
Keywords: lithotripsy; nephrolithiasis; pregnancy complications; pregnancy trimesters; uretero-lithiasis; urolithiasis;
Neuropsychiatric symptoms are frequently associated to renal dysfunction and may compromise negatively the clinical course as well as the quality of life, and the functional status of the patients. The neuropsychiatric disorders associated with renal disease may present various forms according to the natural history of the disease, and remain underdiagnosed and undertreated. There are few data in the literature regarding the treatment of these patients, and a lot of controversies still exist. The objective of this paper is to describe the most frequent neuropsychiatric disorders in patients with renal diseases.
Keywords: acute kidney injury; anxiety; depression; kidney diseases;
Familial Hypomagnesaemia with hypercalciuria and nephrocalcinosis, with severe ocular impairment secondary to claudin-19 mutation, is a rare recessive autossomic disorder. Its spectrum includes renal Mg2+ wasting, medullary nephrocalcinosis and progressive chronic renal failure in young people.
To report a case of kidney transplantation father to daughter in a familial occurrence of severe bilateral nephrocalcinosis associated with ocular impairment in a non-consanguineous Brazilian family, in which two daughters had nephrocalcinosis and severe retinopathy.
The index case, a 19 years-old female, had long-lasting past medical history of recurrent urinary tract infections, and the abdominal X-ray revealed bilateral multiple renal calcifications as well as ureteral lithiasis, and she was under haemodialysis. She had the diagnosis of retinitis pigmentosa in the early neonatal period. The other daughter (13 years-old) had also nephrocalcinosis with preserved kidney function, retinopathy with severe visual impairment, and in addition, she exhibited hypomagnesaemia = 0.5 mg/dL and hypercalciuria. The other family members (mother, father and son) had no clinical disease manifestation. Mutation analysis at claudin-19 revealed two heterozygous missense mutations (P28L and G20D) in both affected daughters. The other family members exhibited mutant monoallelic status. In despite of that, the index case underwent intrafamilial living donor kidney transplantation (father).
In conclusion, the disease was characterized by an autosomal recessive compound heterozygous status and, after five years of donation the renal graft function remained stable without recurrence of metabolic disturbances or nephrocalcinosis. Besides, donor single kidney Mg2+ and Ca2+ homeostasis associated to monoallelic status did not affect the safety and the usual living donor post-transplant clinical course.
Keywords: calcium metabolism disorders; genetic diseases, inborn; kidney transplantation; distúrbios do metabolismo do cálcio; doenças genéticas inatas; transplante de rim;
Cat Scratch Disease (CSD) is an infectious disorder which appears after cat scratching
particularly in children and adolescents.
Keywords: adolescent; health care (public health); immunosuppression; adolescente; avaliação de processos (cuidados de saúde); imunossupressão;
The potential risks related to drug exposure during pregnancy represent a vast chapter in modern obstetrics and data regarding the safety of antihypertensive drugs during pregnancy are relatively scarce.
A 37-year-old patient discovered her fifth pregnancy at our hospital after 26 weeks and 4 days of gestation. She reported a history of hypertension and was currently being treated with Losartan. Hospitalization was recommended for the patient and further evaluation of fetal vitality was performed. On the fourth day an ultrasound was performed, resulting in a severe oligohydramnios, fetal centralization and abnormal ductus venosus. After 36 hours, the newborn died. Pathologic evaluation: At autopsy, the skullcap had large fontanels and deficient ossification. The kidneys were slightly enlarged. A microscopic examination detected underdevelopment of the tubules and the presence of some dilated lumens. Immunohistochemical detection of epithelial membrane antigen was positive. Immunoreactivity of CD 15 was also assayed to characterize the proximal tubules, and lumen collapse was observed in some regions.
Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor antagonists (ARAs) are among the most widely prescribed drugs for hypertension. They are often used by hypertensive women who are considering become pregnant. While their fetal toxicity in the second or third trimesters has been documented, their teratogenic effect during the first trimester has only recently been demonstrated.
Constant awareness by physicians and patients should be encouraged, particularly in regard to the prescription of antihypertensive drugs in women of childbearing age who are or intend to become pregnant.
Keywords: angiotensin receptor antagonists; hypertension; pregnancy complications; toxicity; antagonistas de receptores de angiotensina; complicações na gravidez; hipertensão; toxicidade;


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Find the best value hotels near Gosford!
Only 2.5 km from Gosford CBD, The Willows Gosford Hotel with a range of 3.5 star AAA-rated rooms offer a relax and comforting accommodation to Central Coast visitors.
There is abundant activities to do and places to see at Central Coast. Here just a few popular local attractions in Central Coast area to put into your travel plan.
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- Australian Reptile Park
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- Gosford Regional Gallery (Japanese Garden)
- Gosford Classic Car Museum
- Terrigal Beach (Cafe & Food Terrigal)
- The Skillion (Terrigal)
- Staples Lookout (Woy Woy)
- Firescreek Fruit Wines (Holgate)
- Avoca Beach Picture Theatre (Avoca Beach)
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Perhaps I've been studying too much Modernist architecture, but the phrase 'Less is More' seems to have sunk into my mind-set, and my cooking. Of course, it could also be the tight bank budget caused by staying at uni during Easter to revise / balls & graduation tickets / desperate impulse eBay buys spurred on by hopeless boredom from revision. Whichever way you look at things, chicken is expensive and, as I refuse to buy an animal that has effectively been tortured its whole life, I can't bring myself to buy anything other than free range. So I thought I'd share with you how I managed to use pretty much every part of such a pricey purchase!
Firstly, I buy a whole chicken, and cut it into parts. After all, a couple of chicken breasts can cost you the same as a whole bird, so you might as well start sharpening your carving knife. This delightful chap taught me how to do it, and it's actually pretty easy if you follow the lines on the meat itself (what can't you learn on youtube?! It's brilliant). Once cut up, I divide the thighs, drumsticks, wings & breasts I'm left with and bag them up for the freezer – you can get plenty of meals out of them already!


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From publisher blurb:
Bravely you have served your adopted city since the day of King Kalak's fall. As slaves and rebels you rose from Kalak's slave pits to claim your freedom from his ancient tyranny. Now that freedom is being threatened once again by an insidious new enemy, one who controls the use of psionics throughout the dying world of Athas!
The Dragon's Crown adventure is the exciting climax of the Freedom module series in one final journey of epic proportions, the player characters must defend everything they have worked so hard to build. Seven adventures connected by one great plot take the PC's from the volcanic islands of the Sea of Silt to an ancient wonder hidden in the forests of the Dragon Crown Mountains. The grandest and most ambitious adventure of the Dark Sun game world, Dragon's Crown will provide many hours of exciting play!


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Discussion Starter • #1 •
I have a 1990 GL1500SE that has been stellar for years. We ride her all the time. Last week I went to ride her and she acted like she had a dead battery. I put on the charger all night and the next day tested the battery. It was good. Still, the headlights and none of the guages/dash lights worked (save the cruise control "on" light on the dash). She wouldn't crank-not even a click. The radio works, the clock works, blinkers work, brake lights work. I reviewed several threads on the forum. I have checked the starter button and cleaned it (it seemed fine but I couldn't check any voltage going through because there was no voltage getting to it. I assume that it was good.) I checked the on/off switch. The cruise control light on the dash would go out when I switched it off so assume that it is working. I checked the main fuse connected to the solenoid-it was good. The "dogbone" fuse by the battery was good. The "dogbone" fuse behind the fuel tank was good. The fuses in the fuse box were all good and tested good when the key was "on". The two "reverse" fuses were good. So I moved to the "reverse switch". The switch itself seemed fine. It made good connection and "clicked" when activated. I checked for voltage going through any of the 3 wires going to it-nothing. I checked the "pigtail" feed leading up to the switch. I didn't find any voltage coming out of the pigtail. So my question is-- should there be voltage going to the reverse switch and if so what do I check next? Could a relay be bad, which one, and how can I check it? Thanks for the help.


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Material: Suede and Metal
All products are subject to availability, prices may differ in-store.


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Planned Parenthood has resurfaced as front and center of the abortion debate when a video surfaced of Planned Parenthood executives discussing selling aborted fetuses.
Cecile Richards, president of the organization, said that all practices are within the law and ethical, but admitted the video revealed a lack of compassion:
"Our top priority is the compassionate care that we provide. In the video, one of our staff members speaks in a way that does not reflect that compassion. This is unacceptable, and I personally apologize for the staff member's tone and statements."
Planned Parenthood should be defunded of federal funding for the simple fact that taxpayers should not see their money funded to the largest abortion provider.
In 2009 alone, affiliates performed 332,278 abortions and had only 977 adoption referrals. That means that over 97% of the services provided ended up being an abortion.
In 2012, Planned Parenthood made records, but the numbers are cringe worthy. They performed almost 334,000 abortions and saw revenues exceed $87 million.
Planned Parenthood has an extensive negative impact on the back community. While blacks make up for almost 12-15% of the U.S. population, Planned Parenthood clinic are located in 78% of minority communities.
Margaret Sanger, the founder of Planned Parenthood, wanted to hide behind religion to cover up her bigotry and racism towards blacks:
"We should hire three or four colored ministers, preferably with social-service backgrounds, and with engaging personalities. The most successful educational approach to the Negro is through a religious appeal. We don't want the word to go out that we want to exterminate the Negro population, and the minister is the man who can straighten out that idea if it ever occurs to any of their more rebellious members."
If government is reconsidering the Confederate flag because of its oppression towards a certain segment of people, surely the funding of Planned Parenthood should be reevaluated in wake of its stance against humanity.


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Happy 4th of July
Where does your sugar come from? Most people only know about Sugar Cane, but for many in the USA, Sugar Beets are a great way to get sugar from non-tropical areas. Sugar Beets do best in sandy soils and cooler climates. So Michigan and Minnesota thrive as the home to a large percentage of the US Sugar Beet Crop. Check out the Sugar Beet Association What is the Byproduct of sugar beets? Sugar is the primary reason we grow them, but the sugar beet pulp that remains after the sugar extraction has found many homes for animal feed. I was initially introduced to beet pulp while preparing my first...Read More
Useful ingredient that enhances texture & meets the demand for healthy, high fiber foods/feeds.Read More
Alfalfa dehy is produced from standing alfalfa, which is mowed and chopped in the field, delivered to the dehydrating plant still containing a minimum of 60 percent moisture, artificially dried, ground and pelleted. Dehy can replace a portion of both the grain and the forage in rations for milking cows. It can replace up to 50 percent of the conventional forage dry matter in the ration, but at this level the ration should contain no more than 50 percent grain, on a dry matter basis. Research at the University of Nebraska has shown that the protein in dehy tends to be degraded in the rumen to...Read More
Horse Expo Pomona
When you use Google services, you trust us with your information. This Privacy Policy is meant to help you understand what data we collect, why we collect it, and what we do with it. This is important; we hope you will take time to read it carefully. And remember, you can find controls to manage your information and protect your privacy and security at My Account. There are many different ways you can use our services – to search for and share information, to communicate with other people or to create new content. When you share information with us, for example by creating a Google Account,...Read More


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The Joint is a music rehearsal studio located in King's Cross, London. Learn more about The Joint and book easily online with KORUS (formerly Rehearsal Booker). We are London's No.1 rehearsal studio booking site. Simply choose a studio that suits your location and price range, press 'Reserve' and enter the details of your booking. We'll then confirm your booking via email.
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Vrindavan Farm Organic Aamrass
Pure Organic Aamrass
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Aamrass prepared from our organic hapus and kesar mangoes.
100% Pure pulp - no added sugars or preservatives.
The rass is stored in ziplocks and frozen to bring you the mango season all year!
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Off-campus SJSU users: To download campus access theses, please use the following link to log into our proxy server with your SJSU library user name and PIN.
Publication Date
Spring 2014
Degree Type
Thesis - Campus Access Only
Degree Name
Master of Science (MS)
Computer Science
Thomas Austin
compression, detection, malware, metamorphic
Subject Areas
Computer science
Recent work has presented a technique based on structural entropy measurement as an effective way to detect metamorphic malware. The technique uses two steps, file segmentation and sequence comparison, to calculate file similarity. In previous work, it was observed that similar malware have similar measures of Kolmogorov complexity. A proposed method of estimating Kolmogorov complexity was to calculate the compression ratio of a given malware which could then be used to cluster the malicious software. Malware detection has also been attempted through the use of adaptive data compression and showed promising results. In this paper, we combine these concepts and propose using compression ratios as an alternative measure of entropy with the purpose of segmenting files according to their structural characteristics. We then compare the segment-based sequences of two given files to determine file similarity. The idea is that, even after malware is transformed using a metamorphic engine, the resulting variants still share identifiable structural similarities with the original. Using this proposed technique to identify metamorphic malware, we compare our results with previous work.
Recommended Citation
Lee, Jared, "Compression-Based Analysis of Metamorphic Malware" (2014). Master's Theses. 4428.
DOI: https://doi.org/10.31979/etd.g4bn-x6be


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Celtic FC Touchscreen Glove – Official Licensed Product Adult Black. Smart touch technology – use any touch screen without taking your gloves off. High-quality warm knitted gloves, ideal for at the game, outdoor activities and gifting. 46% Polyamide 45% Acrylic 5% Copper 4% Elastane. Unisex design. Suitable for adults – size: 24 x 13.5cm.
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text: Christian Day is a modern day Warlock living in the Crescent City of New Orleans, Louisiana and is co-host of HexFest with his husband, Brian Cain. A practitioner of the ancient arts of Witchcraft—a spiritual path devoted to old world folk magic, healing, and veneration of the dead, Christian owns two occult shops in Salem, Massachusetts: HEX: Old World Witchery, dedicated to the practices of Witchcraft, Hoodoo, and Conjure, and OMEN, a psychic parlor and Witchcraft emporium which features a staff of gifted psychic readers. In 2012, he also opened a Hex shop in New Orleans, where he now lives. Each October, Christian hosts Festival of the Dead, an annual event series in Salem that includes such popular events as the Official Salem Witches' Halloween Ball, an Annual Psychic Fair and Witchcraft Expo, and an authentic séance. Among his many media appearances, Christian has been featured on The Travel Channel's Ghost Adventures, Showtime, TLC, MSNBC, Biography, Dish Network and in The Chicago Tribune, The Wall Street Journal, The Boston Globe, The Boston Herald, CNN.com, USAToday.com and, of course, The Salem News.


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From the first steam-powered vehicle, through the introduction of affordable mass-produced gasoline-guzzlers, to the latest futuristic flying automobile concepts, humankind's love affair with all things automotive shows no indicators of abating. Rarely do I attempt to "enhance" or "fix" manufacturing cars with my chops. I actually simply try to bring my own style to the automobiles I Photoshop. An exception lately is the brand new C7 Corvette. Each time I Photoshop one I'M attempting to fix it, lol. There are some nice things about it and a few ghastly issues about it. The issues I see range from the small, ie too many black vents, louvers, and crap, to the big, ie, that rising beltline, rear quarter window and awkwardly formed rear hatch glass. I nonetheless don't look after the taillights both, however I've carried out a number of renderings with the correct quad circular models, so I've let that go, lol.
We help our shoppers in markets across the world to create methods that cover all the manufacture and sales process. Our experts establish efficiencies and opportunities that assist business technique, delivering direct financial worth whereas minimizing emissions and using fewer of the planet's treasured natural assets. Fujitsu is a strategic companion to the worldwide automotive business. We offer world-class expertise, services and solutions for bettering efficiency, lowering prices and serving to our multinational shoppers acquire maximum benefit from their global assets.
Dave's Final Automotive is a household owned and operated auto service heart serving North Austin, Central Austin, Pflugerville, Cedar Park, Round Rock, College of Texas and surrounding areas since 1997. We have now earned our place within the NAPA AutoCare program so regardless that we are an impartial firm, our work is warrantied nationwide. Our staff of frequently trained service advisers and technicians is genuinely captivated with … Read More


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Every time society embraces a new trend, hundreds of new companies pop up overnight. Lately, the country's been on a health craze, meaning a lot of new healthy restaurants have popped up overnight. Most of them barely survive, usually because of celebrity press, but some survive on their own merit.
Sweetgreen is one of those new restaurants. The high-end salad chain opened its first store in 2007. Since then, co-CEO Nathaniel Ru's been present at all of 40 locations' openings. In Ru's words, Sweetgreen is unlike any other restaurant because they stand for something more than profit.
There's a lot that other legacy restaurants could learn from Sweetgreen. While most people wait for trends to take over, Sweetgreen starts them. Before the world caught on to the technology craze, Sweetgreen already implemented several features that allowed customers to use technology to place and receive orders via a website or mobile app. Learn more about Michael Lacey: http://fortune.com/2016/02/18/sweetgreen-entrepreneurs/ and https://www.bizjournals.com/losangeles/potmsearch/detail/submission/6435405/Nathaniel_Ru
With technology as part of the company's DNA, it ensured Sweetgreen's spot on the map. Once they were on the map, they needed to figure out a new way to lead their company. The co-founders didn't want to go the traditional corporate headquarters route. Instead, they created their own bicoastal management strategies.
They've come a long way since their first restaurant in Georgetown. Shortly after graduating, they wanted to start their entrepreneurial careers. The first step: identifying marketing opportunities that they could afford to pursue. Upon close inspection, they found that Georgetown lacked any healthy eating options, particularly, near campus.
Their first store was on campus and tailored directly to students. Thanks to their use of technology, the younger generation picked up on Sweetgreen's vibe early on. The company did well until winter break when most of the students leave on vacation. Yet, Sweetgreen found a way to survive the dry spell. Read more: Nathaniel Ru | Crunchbase and Nathaniel Ru Blazes a Trail in The Height Food Industry | Affiliate Dork
It's also extremely important that restaurant owners determine why people should visit their store. Most food chains cluster around corporate offices, hoping to attract lunch-time diners. That method works well as long as the number of restaurants stays low and competitive. Too much competition and no one makes money.
Sweetgreen thought it'd better if they focused on becoming a part of the community. They look for affluent neighborhoods that are more likely to welcome a healthy restaurant.


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Samsung Galaxy S7 edge, Major US Carriers, 75 Units, Other Condition, LCD Line/Dot Stock, Jacksonville FL
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Remember when easily making money from your content was just a dream? With WebKite, that dream is now a reality. Through our unique publishing platform, you can leverage the content that you're passionate about to make money and help people make… Read More
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Bing It On – The Modern Day Pepsi Challenge
Walking into grocery stores as a young child, I'd get overwhelmed at the prospect of blind taste tests. Drinking competing milks, eating rival cheeses, and consuming adversarial donuts was a treat because it meant I got to eat twice the… Read More