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George ENESCU (1881-1955) Impressions denfance, (Impressions of Childhood) op.28 (1. Ménétrier (Minstrel) [3:44]; 2. Vieux mendiant (Old Beggar) [3:12]; 3. Ruisselet au fond du jardin (Stream at the bottom of the garden) [2:37]; 4. L'oiseau en cage et le coucou au mur (The bird in the cage and the cuckoo on the wall) [2:18]; 5. Berceuse (Lullaby) [1:44]; 6. Grillon (Cricket) [0:21]; 7. Lune à travers les vitres (Moonlight through the windows) [2:38}; 8. Vent dans la cheminée (Wind in the chimney) [0:32]; 9. Tempête au-dehors, dans la nuit (Storm outside, at night) [2:14]; 10. Lever de soleil (Sunrise) [3:50])
Erwin SCHULHOFF (1894-1942) Sonata No.2 for Violin and Piano (1927) [16:15]
Bela BARTÓK (1881-1945) Sonata No.2 for Violin and Piano, SZ 76 [20:39]
Peteris PLAKIDIS (b.1945) Two Grasshopper Dances for Solo Violin [2:03]
Gidon Kremer (violin); Oleg Maisenberg (piano)
rec. Teldec Studios, Berlin, January, May 1996
This is the third outing for this music, first released on the Teldec label in 1997, then in Warners Elatus edition in 2004 and now again on Warner Classics. I hope it has been successful on each occasion as it certainly deserves to be. The music is very typical of the period in which it was written (19211940), a period of much experimentation and innovation.
Enescu was a violinist and teacher among whose pupils were Yehudi Menuhin, Christian Ferras, Ivry Gitlis, Arthur Grumiaux and Ida Haendel. It was his devotion to teaching that prevented him from being a more prolific composer. His Impressions of Childhood was written in 1940, the most recently written piece on the disc - apart from the bonus track. It is a beautifully constructed set of miniatures lasting from a mere 21 seconds to just under four minutes and is full of gorgeous melodies shared equally by each instrument, save the first which is for solo violin. Ive never heard birds more convincingly portrayed in music than in track 4 The bird in the cage and the cuckoo on the wall, including Messiaens Catalogue doiseaux and Rautavaaras Cantus Arcticus for birds and orchestra, evocative though they both are. The same goes for the little cricket of track 6. Folk influences were always a feature of Enescus work and are amply demonstrated here right from the first piece entitled Minstrel which easily brings to mind the Romanian gypsy violinists so typical of that country. Lullaby is, Im sure, a folk-song pure and simple and would be recognized by most of his compatriots. Each piece moves seamlessly to the next giving a musical unity to the whole set, finishing with Sunrise that concludes with, as the liner-notes describe an ecstatic outpouring from both violin and piano.
Erwin Schulhoff, whilst being the lesser known of the three main composers on the disc is, Im glad to say, becoming better known each year and rightly so. An extremely talented composer, born in Prague, his ability was recognized early in his life by Dvorák no less who recommended that he pursue a musical career. However, as a Jew and a communist his fate was sealed once the Nazis occupied Prague and following his arrest in 1941 he died in the Wülzburg concentration camp in 1942 of tuberculosis. His violin sonata of 1927 shows what a huge talent the world lost in the Holocaust. It is a muscular work of complexity and inventiveness which, once again owes much to the folk music of his native land. It opens with a powerfully stated theme that is developed throughout the movement, and is as impetuous as Allegro impetuoso implies. The second movement is calm and introspective with the piano taking a backseat role. The third movements title Burlesca: Allegretto again amply describes its content with notes tumbling out before fading away and the Finale: Allegro risoluto brings the music back to the beginning. The opening theme is treated to a gentler approach, the promised resolution occurs and the work comes to a satisfactory conclusion.
Bartóks two violin sonatas were written in 1921-1922. The second is a superb work typical of the composer. It owes its influences to folk music of which Bartók was an inveterate collector. A work of its time yet ahead of it, the sonata was written only two or three years after Elgars Cello Concerto; it couldnt have come from a more different sound world what would Elgar have made of it I wonder! The work is as contemporary as anything composed today but is often playful and capricious and cannot fail to make you smile at times. It begins in a reflective mood but the music becomes disturbed and restless before settling down towards the end of the first movement. The second movement begins with some plucked passages before Bartók tests the abilities of the performers with some tough challenges that the two artists here meet with consummate ease listen to the second movement from 7 minutes in to see what I mean.
All the works on the disc require expert hands to deliver the performances the music must have to make it speak to its audience with conviction. It is difficult to imagine that they could be bettered. Gidon Kremer is, after all, an exceptionally gifted violinist who understands everything he tackles every which way and can contrast powerful playing with the most delicate touches. Sometimes, when required, he is able to make his violin whisper at the very margin of audibility, whilst Oleg Maisenberg is a brilliant and musically sympathetic partner who perfectly complements his colleague.
The disc is rounded off with two short pieces by Kremers Latvian compatriot Peteris Plakidis Two Grasshopper Dances for Solo Violin. These once again sound folk-inspired, and are a fitting way to come back down to earth after some wonderfully robust music.
This disc represents a wonderfully musical celebration of three major works for violin and piano from the first half of the twentieth century. It will have you reaching for it often.
Steve Arloff
A wonderfully musical celebration of three major works from the first half of the twentieth century.


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subset: commoncrawl


text:
'This collection provides numerous and refreshing insights into the claims about the ever more proactive role of users of information and communication technologies. Through a variety of case studies, illustrating the array of theoretical frameworks available, the authors throw light upon the diverse ways in which users engage with innovations. From outlining the challenges of involving users in design, through appreciating the diverse origins and nature of user engagement with ICTs to critically commenting upon the constraints of the user experience, this book provides a welcome and useful contribution to the field.
In presenting examples from the most extensive and demanding fire in modern Swedish history, this paper describes challenges facing hastily formed networks in exceptional situations. Two concepts that have been used in the analysis of the socio-technical systems that make up a response are conversation space and sensemaking. This paper argues that a framework designed to promote understanding of the sensemaking process must take into consideration the time at which as well as the location in which an individual is engaged in an event. In hastily formed networks, location is partly mediated through physical systems that form conversation spaces of players and their interaction practices. This paper identifies and discusses four challenges to the formation of shared conversation spaces. It is based on the case study of the 2006 Bodträskfors forest fire in Sweden and draws on the experiences of organised volunteers and firefighters who participated in a hastily formed network created to combat the fire.
This paper proposes a model for describing resilience in emergency management of irregular events. The purpose of our model is to describe three parallel developments in an emergency response scenario. Namely, changes in the ongoing events processes, the actors' sensemaking and control functions, and the technologies used for sensemaking and control. Focusing on the three separate developments enables identifying resilience in the choice of control functions and technologies in response to foreseen and actual process changes, their consequences and new disturbances. Our model was created following an emergency exercise that proved to be difficult to analyse with respect to resilience using existing models. We use the exercise to illustrate and apply our model through a qualitative analysis.
This paper discusses how various actors communicate about and coordinate sea rescue activities in networks. We combine a network approach with theories of inter-organization communication to understand how communication can facilitate or limit coordination in networks. Search and rescue officers retain the overall authority to direct rescue missions, and coordination with several other professions is central to this. When coordinating different professional actors in a network it is important to develop trust, legitimacy, and a shared and uniform understanding of the situation and of how to act. Communication deficiencies often result from the fact that involved actors belong to different organizations with different cultures or representing different professions. The greatest gap we found was between those working and not working at sea, and between those habitually or seldom involved in rescue activities. Communication comprises more than simply exchanging information; it also entails the forging of relationships, to facilitate future coordination and cooperation and to develop mutual trust and understanding. In any rescue operation it is important that the actors interpret communication in the same way and act according to a shared pattern. Joint training and follow-up are important conditions for continuous learning and development in this regard.
The complexity and diversification that characterise society of today arereflected both in socio-technological systems and labour organisations but also in the renewal of the language a profession uses. The transfer of knowledge, meaning and understanding through communication between people is not neutral and unproblematic.
In the Maritime Search and Rescue Service different professionals withdifferent norms, knowledge bases and use of technology have to communicate effectively in order to be able to carry out their duties in the best way possible. The Maritime Search and Rescue (sAR) undergo big changes and the activities make great demands on co-ordination, organisational as well as geographical. The development of ICT has lead to new technology and new organisational structures being established within the former organisation.
Information and communication technologies (ICT) are a condition for the inter- and intraprofessional communication in the modem Maritime Search and Rescue Service. Its participants are found in geographical separated pockets of local order, which together creates the virtual pocket of local order of Maritime Search and Rescue organisation. ICT makes it possible to coordinate all the activities that are needed to create an order (temporary pockets of local order) at SAR operations. Further, ICT create new and big potentials for learning. They are however not yet fully used, partly because the different actors during their everyday work at the same time handles both old and new ICT. Rules and laws restrict the cooperation between the different organisations in the same virtual and local pocket of local order but the cooperation is also restricted by how ICT is used in its socio-cultural context.
Demola is both a concept and an international organization that facilitates co-creation projects between university students and companies, either locally or internationally. The network consists of various partners including universities: faculties, researcher as well as students but also of both local and international companies, and different types of agencies. The co-creative concept aims to solve real challenges where the outcome can be a new concept, a demo, or a prototype. If the partner company finds the students' outcome useful, the company can license or purchase it, and take it for further development. The framework makes is easy for partners outside the university to cooperate with student groups. Each partner has a clear role, and the work is guided by simple procedures. Contracts, intellectual property rights, licensing models, and other legal requirements are in place and meet international business standards and practices. At Linköping University the Demola concept is implemented through the course Cross Disciplinary Projects that also is designed to meet the demands expressed in the CDIO Syllabus. What makes this course unique and different from other project courses is that students from the Faculty of Arts and Science, The Institute of Technology and the Faculty of Health Sciences are working together in one course towards the same goal. The students are participating in the work order to creatively and independently contribute with expertise from their different areas and therefore the course is open only to those who are at the end of their studies. The course is conducted in the form of independent cross disciplinary projects. The briefs are externally specified from companies or other interested parties who wish to have an idea eloborated or a problem solved. In addition to the project some lectures are given, for instance in applied ethics and inter professional communication. Upon completion of the course the student is expected to have acquired knowledge and understanding concerning how to independently work on issues related to the knowledge and skills previously acquired in education. The course also aims to enforce their capabilities and competences regarding communication with representatives of other professions since they are expected to demonstrate ability to work in a team and in close collaboration with other professions. Demola is now listed by OECD and World Bank Group as a best practice for innovation policy-makers globally.
This paper will describe and try to understand how user together functions as innovators when they use already established information and communication technology (ict) in creative ways. The paper describes two case studies that both are about mobile recreational activities in nature, namely elk hunting and bird watching. Both these cases show that the social context plays a significant role in the introduction and use of ict and that the development takes place in interaction between individuals. In the first case, producing users, in this case (the hunting association and its web editor) that starts and in some way monitors the development while in the later case it is both producing users and everyday users (different bird watchers with different technological knowledge and competence) that during different development stages are active. Both cases show that it is a process innovation and that it could be enabling and constraining in the same time depending on which virtual pocket of local order the user belongs to.
The aim of the course is to create understanding for how to be an engineer; this is achieved by imitating the situation many engineers face when they are introduced into the workplace. As a new employee at a company, it is often many things the students need to learn in a short amount of time. In the course the students are expected to take on the role of a new employee in a company. They are expected to learn about the technical-, group-and project aspects that are needed for working within the company. The student is expected to live up to the company's requirements for technical solutions, professional communication with customers and internal requirements. They learn to cooperate actively with the project members/customers/experts with different backgrounds and knowledge and see how organizations influence the structure of the team and the individual's freedom of action. In addition, they must learn to see the big picture and thus reflect on societal and ethical aspects. They also gain knowledge of the organization's significance from an economic perspective and how organization affects the team structure and process which in turn can affect an individual's freedom of action and behavior. The course is connected the CDIO Syllabus v2.0 in that sense that the student shall
As natural and man-made disasters become increasingly common, ensuring effective disaster response, mitigation and recovery is growing into a high-priority task for governments and administrations globally. This paper describes the challenges of collaboration within multi-organisational hastily formed networks for post-disaster response, which are increasingly relying on emerging ICT infrastructures for communication and cooperation. We present an interdisciplinary analysis of the conditions for establishing an effective mutual conversation space for involved stakeholders, and how the development of socio-technological systems affects cognitive and behavioural aspects such as established communities of practice and virtual pockets of local order.
Our observations thus far suggest that some of the key issues are overcoming organisational and cultural heterogeneity, and finding solutions for technical interoperability, to ensure effective, pervasive and sustainable information exchange within and between organisations participating in hastily formed networks.


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Our members and partners
The Social Interest Group welcome conversations with organisations right across the health and social care spectrum. Our members and partners benefit from greater strength and development opportunities, whilst retaining their unique identity and services.
We want to talk with you about partnering with us, becoming a member of our group or developing entirely bespoke initiatives together.
You can read more here about the benefits of working together, the services we offer and the sectors we represent.
Organisations who are working with children and young people, older people, people with physical disabilities or learning disabilities, BME groups, people with housing needs, carer and family support services, are particularly welcome to get in touch about working together.
Current members and partners of the Social Interest Group:
Penrose provides person-centred support, health and social care for people with a history of offending and mental ill health. With over 45 years' experience, Penrose operates in a range of community based, supported housing and residential settings. Penrose works with clients who have mental health and forensic mental health needs, including adults with personality disorders. Their work centres around giving vulnerable members of our society the voice, skills and independence to build a brighter future. The Penrose Criminal Justice team work in partnership with MTC Novo and London CRC, delivering the Transforming Rehabilitation Programme.
In the past year Penrose has supported over 11,500 Service Users:
- Residential services – 319
- Synergy services – 1540
- Roots – 63
- Mental Health Floating Support – 36
- Steps – 81
- Community Criminal Justice Service – 2928
- Prison Criminal Justice Service – 6565
For more information, please visit the Penrose Options website.
Equinox Care provides personalised support, care and recovery to people with multiple and complex needs. This includes people who experience mental ill health, drug dependence and alcohol dependence. Equinox clients may also have a history of homelessness or offending. They may have been turned away from other services, due to the complexity of their needs. Equinox assists their service users to solve or manage the issues that are relevant to their own lives, including achieving stable accommodation, recovery and independence.
The heart and soul of Equinox is providing hope without exclusion to all those who come to them. They do this across London and in Brighton. They recently won four new contracts in Ealing – one of which is a service run by Service Users for Service Users.
Equinox has supported almost 1,500 people in 2016/2017.
For more information, please visit the Equinox Care website.


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Your smart home wants to save you from a fire. Thanks to a new integration between Nest Protect and GreenIQ Hub, if the Nest detects smoke, the GreenIQ Hub will turn on your sprinkler system, serving as a potentially lifesaving antecedent to the fire department. GreenIQ, the Tel Aviv-based Internet of Things startup, was initially conceptualized as a smart irrigation controller, but now the company is finding new ways to leverage its abilities. Not only will it help you save water, it could help you save yourself.
"It has always been our mission to help make gardens smarter and allow people to feel more connected to their green spaces," said Odi Dahan, founder and CEO of GreenIQ. "Our integration with Nest is taking it one step further by not only helping our customers save money and conserve water, but also helping to decrease any anxiety people may have about potential fires."
Not only will Nest activate GreenIQ in the presence of smoke, but the Hub will also flash outdoor lighting anytime Nest Protect detects an emergency of any kind. This could help alert your neighbors to potentially dangerous situations, saving precious time in calling the appropriate authorities. With more than 2,500 lives lost each year due to home fires in the U.S., and another 12,600 injuries, any innovation in the smart home space to prevent these tragedies comes as a welcome development.
Of course, the GreenIQ Smart Garden Hub offers a number of other non-fire-related benefits as well, including the management of your watering systems, determining the ideal watering conditions, and gaining key insights into your green spaces (such as potential leakage or insufficient water flow).
So if you're looking for a way to turn your tech-savvy garden into a fire-prevention system, look no further than the GreenIQ Hub and Nest.
Editors' Recommendations
- These 3 transformative technologies will have the biggest impact on 2020
- Amazon discounts the Nest Protect smoke alarm down to $99 for Black Friday
- Amazon cuts prices on Blink, Ring, Arlo, Nest, and Eufy 2-cam outdoor security
- How to set up a Google Nest Hub Max
- The best smart home tech of CES 2020: Lockly Vision, Lucy Vacuum, and more


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On Monday night, President Barack Obama reminded many why they fell in love with him when he took part in a tribute for former "Golden Girl" Betty White.
SEE ALSO: The Case Against Liberal Despair
Sitting in the Oval Office, President Obama writes a congratulatory note to White:
Dear Betty,
You look so fantastic and full of energy, I can't believe you're 90 years old. In fact, I don't believe it. That's why I'm writing to ask if you will be willing to produce a copy of your long-form birth certificate. Thanks. Happy birthday, no matter how old you are.
Shortly afterward, "Golden Girls" music cuts on and the President is seen putting a framed picture of White on his desk and then gently rocking out to the theme music. Check out the hilarious video here:
GOP Candidates Go Hard on Romney
Reheating The Tea Party


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I stood on the red glimmering rim of horizon,
groping my way in my quest for secret of life;
I stumbled many a time in the dark region,
and bruised myself in my quest for secret of life!
The red glimmering horizon, turned dark and dim,
I found myself marooned in that dark path
ready to place my head on the guillotine of dull faith
when cries of "Help" and "Ah" vibrated my eardrum
melting my tender heart like soft, sweet butter..I
turned, to realize. life is a circle and I at its center
surrounded by alternating concentric circle of sorrows and miseries,
with traces of small, brief chord like spans of happiness!!
Life is like an inn where we come and go
leaving traces of our sins and virtues and ego
in this wide vulgar sphere where love is craved for
..but here love is lost, never to be got…
palatial mansions, dwarf the dirty dingy dungeons
donning wool and silken garbs they step into their machines
naked bodies and sunken eyes beg for pity in the lanes
here some roll in gold and others in garbage,
here some are free forever, some ever in bondage.
always in quest for secret of life!!
concentric circles ….that whirlpool
the quest for life…
Fervent thoughts on Life* Awesome poems about Quest Artistic poem on Search


text:
Are you searching about ASP.Net Expert Job? Want to get Job inProwareness Software Services Private Limited? You have a very good opportunity to become an Employee of Prowareness Software Services Private Limited. RecentlyProwareness Software Services Private Limited Pvt Ltd Company has announced the walk in for ASP.Net Expert.
Company Name: Prowareness Software Services Private Limited
Job Position Name: ASP.Net Expert
Job Type: IT/Software
Required Educational Qualification:Any Degree/Post Graduate.
Required Experience: Applicant should have 3-8Years of experience. Candidates must have Experience in ASP .Net MVC asp dotnetmvc C# sql server design pattern wcf web forms Web Services.
Work Place:Bangalore
Interview Place:Bangalore
Required Skills:
1.Excellent Communication Skill.
2. Understanding of agile software development practices, especially Lean and TDD
3.Exposure using tooling like Team Foundation Server (TFS 2010/12).
4.Exposure to Unit Testing frameworks like NUnit, MSTest and/or Mocking Frameworks(RhinoMocksetc)
Salary: Best in Industry
Shift: Day/ Night Shift, Ready to Work in Any Shift
Contract/ Agreement: Based on company need and rules
Selection/ Hiring process: Interview
Apply details
Apply Mode: Offline
How to apply? : You should attend the walk-in Interview in given address
Required documents: Latest updated resume, Passport size photos, 10th/12th Mark sheet and degree certificates copy
Walk-in Date, Time and Venue Details
Walk-In Date: 23 Feb – 27 Feb2015
Walk-In Time: 09:00 AM
Venue Details:
# 128/9, 2nd Floor,
"Maruthi Sapphire",
HAL Airport Road, MurugeshPalya,
Bangalore -560017
Company Profile:
Prowareness helps organizations meet their challenges in the field of Software Development. With our International presence with offices in Delft, Netherlands and Bangalore, India and Silicon Valley, US we help businesses with their challenges in Software Development and Testing.Prowareness consists of a team of 50 enthusiastic professionals. This team is a combination of experienced people with great ambition and a clear vision. Entrepreneurship is the key element at Prowareness. Our people therefore constantly challenge themselves to improve our services and to deliver happiness and satisfaction to our customers.
Prowareness is convinced that software development is a profession and that it should be done only by professionals in a professional manner. We help companies with this challenge through our team of developers and consultants who are the best in the field of ICT.
Company Website: www.prowareness.com


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Shared Residence
A Shared Residence arrangement should be the normal arrangement when there are two fit, capable parents; not the rare exception it is now.
Shared Residence (where parents share the legal responsibility and care of the child) was the clear intention of the Children Act 1989. This has never been implemented by family courts.
As parents who live together clearly share the care of their children, we believe this arrangement should continue after separation unless there is a good reason otherwise. This does not mean to say that the children should be shared exactly equally between the parents, but it recognises that the two parents are equally valuable to the children.
After all, most parents living together do not share 'exact' equal time with their children – but no-one would say that one parent is therefore more important than the other.
The present situation, where one parent assumes total control of the child and the other has to make do with whatever is offered, is almost guaranteed to promote problems if the controlling parent wishes it to be so.


text:
Monday, May 26th, 2014
All children are teachers and all adults are their students.
That said, lessons from a 14 month old
–Try anything and everything.
If you like it, do it again and again and again and enjoy the learning
–Take everything in (the mouth usually)
If you don't like it, spit it out
–Let people know what you like and don't like
Immediately and loudly
–Create an environment that works for you
Your toys, your way
–When bored, stop what you are doing and walk away
Let something else draw you
–There are no obstacles
Push, shove, scream for help or walk right over them
–Look before you leap
Think twice about who you want to hug
–Do it yourself, shake off unwanted help
Eat your carrot your way
–Imitate, imitate, imitate
Only people and things that you love
–Work hard to understand how things work
Let go when it doesn't
–Be exuberant whenever you want to
There is no "no,no" for joy
–Be an innocent learner
Say yes until you are sure of "no"
—Plow through life with a smile
All doors will open


text:
Monday, February 27 at 1:15- Pastor Bubba Wright, of The Bubba Adventure" will visit Zion to share the gospel in a very unique way. His message is, "It's not about me or you; it's about Jesus!" He uses fantastic balloon characters to tell His story and to talk about making God pleasing choices in life. All are welcome to join us on Monday for this fun and educational presentation. Many thanks to the First Southern Baptist Church of Independence for making this possible.
School News >


text: Congratulations! You're considering a range hood ventilation solution, and that's a smart move. The fact is, the kitchen is a primary source of poor indoor air quality: excessive moisture, cooking effluents, smoke and grease particulates quickly infiltrate every room in your home. Indoor air can be up to five times more polluted than outside air, which means powerful ventilation is critical to a more comfortable and healthier home environment.


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Siteless CRO
The First Ever Siteless CRO Model
Center Point's siteless CRO model enables clinical studies and research to be conducted at an unprecedented scale and scope as well as in a more time and cost efficient manner than traditional models.
The siteless CRO model combines advanced communication tools with the personal service of specially trained pharmacists to empower study sponsors to adapt to the new world of patient-centric and direct-to-patient healthcare.
The siteless CRO model de-risks the clinical trial process, increases quality, and ensures robust data. These deliverables enable a shorter path to regulatory and commercialization success.
- What are the benefits of using a Siteless CRO rather than a traditional CRO design?
Current clinical trial models are built around geographical clinical sites, and up to 70% of trial patients may not have convenient access to them. Moreover, clinical trial sites vary greatly in speed of communication, cost to recruit and manage patients, and quality of outcomes delivered. The numbers speak for themselves. Clinical trials currently cost approximately $50 billion annually, take six to nine years on average to complete, and may account for almost 40% of total therapy costs
Center Point Clinical Services' siteless CRO model helps solve the current problems associated with traditional models including protocol violations, record-keeping inaccuracies and omissions, informed consent form challenges and inefficiencies and adverse events and safety reporting failure – all which lead to increased costs and longer trials.
- Reduce the risk of your clinical trial not achieving success.
- Test drugs and devices better.
- Rescue failing clinical trials.
Center Point's siteless CRO model uses technology and pharmacist engagement for electronic recruitment and enrollment, along with in-country support as well as direct-to-patient clinical medicine and device distribution. Center Point's siteless CRO and CTRP services also provides technology for data aggregation and a ProRA (Proactive Risk Assessment) data engine. The siteless CRO model unbundles services, increases quality, decreases costs, reduces response time and allows proactive and real-time analysis and action. In addition, it improves patient experiences and engagement, enhances quality of outcomes and reduces clinical trial costs.
- Is the Siteless CRO Model Good For All Therapeutic Areas?
The following types of studies are best suited to benefit from the siteless CRO model:
- Therapies that do not require office visits/assessments or can be done remotely
- Studies recruiting patients in remote geographical areas or where transportation is a challenge (i.e., those with neurocognitive and neurodegenerative disease, Huntington's disease, ALS)
- Studies that require patients to transport large amounts of cold chain medicines
- Studies that require a high volume of office visits
- Studies enrolling complex patient types (i.e., orphan rare disease, geriatric, pediatric)
- Studies that will continue for a long time
- How Does it Work?
The Siteless CRO model leverages the power of the web as a communication and enterprise tool. Center Point's CTRP® service coordinates patient communication using a technology platform that facilitates recruitment and enrollment, electronic data collection (EDC), safety and video conferencing, Direct-to-Patient (DtP) clinical supplies distribution, data aggregation, analysis, and action in real-time. Electronic medical records (EMR) are also used to systematically collect data where appropriate.
Below are a list of the daily and practical deliverables of Center Point's siteless CRO:
- Provides real-time communication to sponsor and steering committee
- Addresses challenges to recruitment, enrollment, and informed consent
- Solves logistical support issues for medicines and distribution
- Confirmation and validation of outcomes and adverse events reporting
- Reduces misunderstanding of outcomes and adverse events definitions
- Enables review of data in real time as per protocol design
- Monitors for outliers in data and data rates
- How Can a Siteless CRO Reduce Recruitment Time?
Site Recruitment
Center Point's siteless CRO model reduces site recruitment time by reaching out to physicians, pharmacists and patients through multiple web-based sites, social media and email. As many as 1 to 10,000 patients can be instantly registered, as needed. Investigators and/or monitors are qualified and recruited using a simple web-based form.
Patient Enrollment
Patients are enrolled using the web, phone, or with the help of medical office or pharmacy staff. Thereafter, a clinical supplies management company distributes the assigned drugs using a courier service such as UPS or FedEx.


text:
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MetalForming Magazine
October 2016 Issue
Volume 50, Number 10
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Cover Article
FABTECH--Sharpen Your Edge
...by attending North America's largest metalforming, fabricating, welding and finishing event: FABTECH 2016. Slated for November 16-18 in Las Vegas, the expo offers unprecedented opportunities to gain insights from visionaries and peers throughout the industry.
The Onus is on Die Designersby Brad Kuvin
...to support the desire of metalformers to do more work--and more complex work--in the die, and avoid costly secondary operations. Design and simulation software increasingly is the tool die shops use to meet the needs of their stamper customers; here's one shining example.
Extreme WeldingA Minnesota maker of aftermarket parts for snowmobiles cut production time by more than 50 percent by switching to wave-pulse gas-metal-arc welding.
Meet Chromate and Offgassing Challenges When Coating Partsby George Gatto Jr.
A plating expert shows how metalformers can help ensure proper part coating and why open lines of communication between metalformers, platers and coaters are musts.
Classifieds: Wanted Skilled Laborby Aaron Wiegel
As an industry we have done a horrendous job of promoting careers in manufacturing. We have allowed people to hold a negative perception of these careers, rather than dispelling myths by sharing the truth. It's time to turn the tide.
Much More Than Tool & Die--One Company's Evolutionby Louis A. Kren
Tooling now is just the tip of the iceberg for Reich Tool & Design. Since its founding in 1965, the Wisconsin company has successfully added precision contract machining and, most recently, cleanroom assembly to its roster of capabilities.
Don't Only Send Managers to FABTECH; Send Your Top Production Workers, TooEditorial by Brad Kuvin
Some Forming Problems Have No SolutionsThe Science of Forming by Stuart Keeler
Advances in Metal-Stamping TechnologyTooling by Design by Peter Ulintz
Tech Update
Additive Manufacturing
Software for Manufacturing
News Fronts
Business Notes


text:
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Fact: Malta is home to the very exciting Popeye Village. Remember the 1980 film? Well the set remained and is now a fun tourist attraction .
Malta has the highest number of public & national holidays a year within the European Union.January 1 - New Year's Day


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Peak District 1
Peak District 2
South Derbyshire
White Peak Ramble
Chatsworth Walk
Rambling in Butterley
Walk in Dark Peak
Derwent Valley
White Peak Walk
Dove Dale Rambling
Ladybower Reservoir
Hiking in Buxton
Limestone Country
South Yorkshire
Leicestershire ramble
This is a previous walk by the Sutton in Ashfield Rambling Club in South Derbyshire. Please click for details of the next walk or a walking calendar.
On Sunday, 24th February 2008 the members of the Sutton Rambling Club will be exploring pleasant countryside and interesting villages on the borders of South Derbyshire and Leicestershire.
This will be a 9 mile easy walk commencing at the village of Worthington and then heading north on the Cloud Trail for approximately a mile and a half .We then leave the trail and move north-west across fields to Breedon-on-the-Hill where we will have a mid-morning break..The ramble then continues west across to the tranquil village of Kings Newton where we will enjoy our lunchtime stop at the Ye Olde Pack Horse (hot food and hot and cold drinks available).
After lunch the walk continues along green lanes and field footpaths taking in the villages of Stanton-by-Bridge and Ingleby. We then proceed along part of the south bank of the River Trent visiting the ancient interconnected caves known as Anchor Church dating back to 1648.
Again after a short mid-afternoon break,the final couple of miles will be over footpaths and finish at the church in Repton in time for a 5.15 pm departure home.
This is an enjoyable but undemanding day and would be an ideal start for new members to get to know us and all about the club. There is no need to pre-book your seat on the coach.
The leader of the ramble is Bernard who can be contacted on 01623 648879
We hire a McEwens coach which leaves Langford Street end, opposite Asda in Sutton at 9.20 am and Bancroft Lane end,Stockwell Gate(near Netto supermarket) Mansfield at 9.30 am.
Please click to see other pick-up points available.
Please note that we have a special event coming up soon (March 1) -a barn dance with pie and pea supper-new faces welcome please contact June on 01623 648879
If you would like further information about the club please phone John on 01623 796396 or Diane on 01623 408704 or click for the 2008 programme of walks and previous walks.


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We offer a robust suite of services for the individual, couple, family and more - if you have a need and it isn't listed below, contact us and we will discuss what we can do to help you move onward and upward.
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A.R.P. Counseling offers a fully certified Level 1 ASAM Treatment Group. Our regular Wednesday night group meets in historic Olde Town Conyers, at 970 Milstead Avenue NE, from 5:30 to 8:30. For information, contact Jim Morton, M.S., L.P.C., Georgia Certified ASAM Treatment Provider, @ (770) 860 8549.
Jim Morton, M.S., L.P.C. has been practicing in the greater Atlanta area for over 20 years. As an Certified ASAM Level One (short-term and long-term) treatment provider, Jim provides clinical supervision of all Alcohol and Drug treatment classes, approved by the Georgia Department of Driver Services for re-instatement of driving privileges. Jim works closely with attorneys, probation officers and other court officials to ensure each client's needs are met.


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Realty World Delta Island
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Bethel Island, California
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AS A FULL TIME PROFESSIONAL REAL ESTATE AGENT, my job is to make your purchase or sale of your property to be simple and professional. I pride myself on offering superior personal service before, during and after your transaction. Knowledge, commitment, honesty, expertise and professionalism are the cornerstone of my business. Let me earn your trust, your business and most importantly your friendship. Don�¢??t make another move without me. I guarantee you will see the difference quality service makes. MY you have a very delightful and safe Holiday season.
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ST. LOUIS — Dorothy Balaban stood up for what she thought was right and got fired.
But last week, Balaban, a former clerk for the Lincoln County (Mo.) Ambulance District, got a measure of satisfaction when a jury ruled she was fired, at least in part, because she talked to a reporter. Jurors awarded her $75,000.
The reporter she talked to was me, when I was covering public safety issues for the Post-Dispatch.
I felt terrible when she was dismissed, so I was glad to see her win her civil suit in federal court.
The victory was an important one for free speech, especially as it relates to public employees who blow the whistle on matters of public concern.
It also said a lot about the bravery and integrity of Balaban, 58, of Troy.
Balaban ran afoul of her employer when she was quoted in a story in March 2006 about Mia Farmer, the chief financial officer for the ambulance district.
Farmer made the news after she was placed on unpaid leave. She claimed she was being punished for trying to stop out-of-control spending on salaries and benefits by a board controlled by the union that represents the district's paramedics.
The district denied the allegations and said Farmer had made costly accounting errors.
I called employees, trying to get to the heart of the matter. Balaban was the only one who would talk to me. She backed Farmer's version. Other employees said they were afraid to go on the record because they feared retaliation at their jobs.
Before the article ran, I let Balaban know that she was the only one who defended Farmer. I asked her if she was sure she wanted me to use her name.
"Sometimes you just have to stand up for what's right," Balaban said.
Balaban said that Farmer had given her life to the district and what was happening to her was "outrageous."
I thought that Balaban's comments might get her a few dirty looks; I certainly didn't think she'd lose her job.
When she called me a week later to say that she'd been fired, she seemed unshaken.
She told me she was raised in a small town in Indiana, with a strict upbringing by her mother, a farm girl, after her father died when she was only 3.
Balaban is ex-military, a retiree of the Air Force with a rank of E-7 master sergeant after putting in 23 years. She has been married for 27 years. She is a mother and a grandmother.
"You just know the difference between right and wrong, and when you see a wrong, you speak out about it," she said. "I just did what was right."
I'm sure Balaban's decision to talk to me was difficult to live with in the coming months as she looked for a new job. She is the sole breadwinner in her family because her husband, Duane, also ex-Air Force, can't work after heart and back surgeries.
Balaban said she filled out 48 job applications but got no offers. She said that she was honest on the job forms and said that she had been fired by her last employer.
"It was depressing, and it was embarrassing," she said.
Finally, Farmer helped her get a job at the Lincoln County Medical Center as a clerk, working the 7 p.m. to 7 a.m. shift.
Balaban decided to sue the district in federal court to get back her lost wages and to clear her name.
I got a subpoena that asked me to turn over my notes from the interview. The district wanted to know which employees I had talked with or tried to interview.
The Post-Dispatch fought the request and won.
I was subpoenaed again when Balaban's case came to trial, and I testified only about what Farmer and Balaban had told me.
The jury unanimously found in Balaban's favor.
Robert J. Wulff, attorney for the district, declined to comment about the verdict or say whether the district planned to appeal.
Farmer told me outside the courtroom that she has a lawsuit pending against the district. She remains on unpaid leave. In the meantime, she is working as a 911 dispatcher for Lincoln County.
"I want to say thanks to Dorothy for standing up for me and the taxpayers of the district," she said. "I'm happy that justice was done."
Balaban said she left the courthouse feeling vindicated.
"What happened was not right, and I did what I should have done," she said.Balaban got back her lost wages and her good name. In my book, she's a hero.


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What a great weekend! Josh and I didn't have much on the radar and as a result we got so much accomplished. Plus I feel rested and recharged. I know the next few weeks are going to start getting hectic and crazy with the wedding getting closer and closer so it was nice to just chill.
Friday night I ended up working late and then went and watched Josh play softball.
Later that night we ordered Chinese food and hungout with our friend for the week, Golden-Eye. She is a pretty cool cat.
The next morning it was time for CrossFit. Although this workout looks pretty simple, IT WAS EXHAUSTING. The burpees killed me. Ugh.
|17:33 Rx
After some breakfast, Josh and I went to a going away party for one of our CF Coaches who is moving to Colorado with his family. It was nice to catch up with some of our friends that we haven't seen in awhile, and say good-bye to Ben and Brandi in such a fun environment. The best thing about CrossFit really is all of the relationships you make.
After the party, Josh and I ran a ton of errands. By 5:30 we were starving. We filled up on leftovers before finishing the series Generation Kill. Have you seen it? Such a great show. It is about the start of the war in Iraq and very eye opening. Also doesn't hurt that Eric from True Blood is in it ;) I highly suggest it! We also watched the movie The Purge which gave us anxiety and led to some heavy drinking.
On Sunday morning we went to church and then walked around Eastern Market. It was pretty warm in the direct sunlight so after a lemonade and pickle on a stick, we hit the road.
After even more errands (I love that Josh lives near a Wal-Mart), we took an afternoon nap and then started working on some wedding things. I love checking things off that to-do list! Later that night we sat outside for dinner al dente: turkey burgers, oven fries, rose wine spritzer for me, and a Dark & Stormy for Josh.
During True Blood, Golden-Eye's owners stopped to pick her up. Josh and I were sad to see her go. She is honestly the coolest cat ever. Now I need one of my own...hint hint.
How was your weekend?
Don't you love productive weekends?
I have seen this in those "what happens in your late 20s Buzzfeeds" where they point out that gone are the days where one stays out till 5am and then sleeps the rest of the day (although that can happen every once in a blue moon, case and point when Alycyn visited last); and more and more often are the days were one likes to wake up early and get sh*t done :)
Did you watch True Blood?
Holy Eric & Jason!


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This week's links: What Will Be the Next Big Thing in the Mobile Space? by James Kendrick. "What I mean by usage driven is the NBT is going to come from creating a new way to do things that people want to do. That may come from online activities, or handling daily tasks or a combination […]
Weekend Reading
April 17th, 2010 · No Comments
Tags: Uncategorized


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ACME LT-6020 Laser tube cutting machine for sale with fiber laser source can cut lines and holes with different diameters from different directions on metal tubes, now the fiber laser tube cutter for sale with good price.
Our laser tube cutting machine can complete processing variety of tube shapes. After cutting the tube section does not require secondary processing, it can be welded directly, greatly reducing the production period, creating enormous value for the enterprise.
It can cut lines and holes with different diameters from different directions on the tubs and cut column and crossed lines at the end of branch pipe to meet centrifugal and non-centrifugal vertical intersection condition for branch and main pipe axis.
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To realize angle groove face,square hole,waist-shaped holes cutting.
With very thin laser beam can be used on small part cutting and complicated patterns and reach to a polished effect.
Cutting Capacity


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The Penalties for Larceny in Western Australia
Crimes involving theft or stealing, which is called larceny under the law, can range from shoplifting to stealing a car. The value of the item stolen is not taken into account in most Australian states, including Western Australia. Larceny differs from robbery because it is considered a non-violent act.
Definition of Larceny
By law, stealing is the act of intentionally taking someone's property to permanently deprive him or her of it. The property must be capable of being stolen, which means the item must be moveable, for it to be charged as a crime. Whether the item is a package of gum from a grocery store or a horse from a ranch, since the item was movable and therefore capable of being stolen, the defendant can be charged with stealing.
Someone may also be charged with stealing if they fraudulently converted property for their own use. A fraud is committed when:
- Someone intends to deprive an owner of all or any part of their property.
- Someone intends to deprive an owner of all or any part of special property.
- A property is fraudulently used as a pledge or security.
- The owner expects the property to be returned, but the defendant may not be able to do so.
- The property is knowingly used by a defendant in such a way that it cannot be returned in the same condition in which it was borrowed or taken.
- The defendant intends to use money as he or she pleases, even though they may intend to repay it someday.
Penalties for Stealing
Most stealing offences will result in penalties of up to seven years imprisonment for convictions. However, there are circumstances in which the penalty may be less or more, depending on what was stolen. If you are arrested for stealing, no matter the value, you need to hire one of the Perth criminal lawyers to defend you.
If a motor vehicle was stolen and driven dangerously, then the conviction could result in a term of eight years in prison. A penalty of 10 years in prison may be the result if:
- Someone steals a testamentary instrument, like a will.
- An employee steals from an employer.
- An aircraft is stolen.
- A director or officer of the corporation steals from their corporation.
Harsher penalties of 14 years can be handed down if:
- Something was stolen while on a person.
- The value of the property stolen from someone's dwelling is $10,000 or more.
- Something is stolen from a vehicle, vessel, or place of deposit used for moving goods from one place to another.
- Something is stolen from a vessel in distress, or one that was stranded or wrecked.
- Something was stolen from a public office where it was kept.
- Something was stolen by picking a lock or using a key to open a box or room where it was kept.
Although the law is clear about why possible penalties differ, you need to hire an attorney if you're facing stealing charges.


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Tanya Veitch
Keller Williams
Brenda Trevino
Florida Home Realty Professionals
Smartphones / PDA's
That's right, our services are free to you because our commission is
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You need to be represented by a buyers agent! Find out more
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Attend our Home
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By Ilyce R. Glink
Nationally-syndicated columnist
Usually found in urban centers or densely populated suburbs, condos (as they are commonly referred to) became popular in the 1970s when state legislatures passed laws allowing their existence.
An apartment building is converted to a condominium by means of a condominium declaration (often called a "condo dec").
New construction condominiums must also have a condo dec.
This declaration divvies up the percentage of ownership, defines which areas are commonly held by all owners, determines who is responsible for the maintenance of the property, and states the condo rules.
One of the most important things to remember about a condo is that you don't actually own the unit in which you live. Instead, you own the airspace inside the walls, ceiling, and floor of the unit, possibly the plumbing within your unit, and perhaps a parking space. (With new construction condos, you sometimes have to buy your parking space separately.)
With your neighbors, you also jointly own what's known as the common elements of the property, which may include the roof, plumbing, common walls, lobby, laundry room, garden area, garden or garage.
Developers building new condos, or renovating an old apartment building to turn it into condos, may keep control of the newly formed condo board or homeowner's association, until a certain percentage of the condos have sold.
This can present some difficulty, especially if there a physical problem with the units (such as a leak) and the homeowners decide to sue the developer.
Another issue to think about is that financing new construction can be tricky. Usually, the developer hooks up with a lender to fund the loans. But the national secondary mortgage market leaders (Fannie Mae and Freddie Mac) require that 70 percent of the units be occupied by homeowners before they will fund a loan. So if you decide to refinance before 70 percent of the units are occupied, you may have some trouble.
(C) 2005 by Ilyce R. Glink. All rights reserved. Ilyce R. Glink is a nationally-syndicated columnist, radio talk show host and the author of many books about real estate and personal finance, including 100 Questions Every First-Time Home Buyer Should Ask (3rd Ed.). For more information, visit her website, www.thinkglink.com.


text: The Occupational Safety and Health Administration of Washington and the !%Laser Institute of America%! of Orlando, Fla., have renewed their partnership for two more years to reduce and prevent worker exposure to laser beam and nonbeam hazards in industrial, research and medical workplaces. The organizations will develop fact sheets with questions that should be asked at facilities that use lasers and will conduct laser safety seminars for OSHA field staff. They also will share information on laser regulations and standards, the effects that lasers have on the eyes and skin, laser control measures and laser safety program administration.


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Teen Depression – Pay Attention to The Warning Signs
Depression in teens might not be easily recognizable. Many young adults will be stoic and often hide their sadness from their families until they are in the throws of deep depression. Growing up is stressful and many teens are in the process of finding out who they are and where they fit in. Not quite an adult, they can't make all of their own decisions, and not still a child they are often encouraged to problem solve on their own to achieve autonomy.
While the greater majority of teens come out the other side happy and healthy, there are still a large number that internalize and combat negative thoughts and feelings to the point where they can no longer cope. This is where they get into trouble and either begin acting out by exhibiting rebellious behavior, or they turn inward and become withdrawn.
For those that are rebellious, the indications that they are in trouble are loud and clear and usually noticeable to most parents. The ones who sit quietly and suffer in silence are the ones that create the most concern. In some cases, these teens appear outwardly happy and seem to have everything going for them, but they have an underlying secret that threatens their sense of self worth.
These teens are the ones that are hardest to reach. The symptoms of teen depression are much like those of depression in general. Withdrawal and lack of interest in activities are common. If your teen was previously active but now would prefer to stay at home and do nothing, you might want to question this lack of interest. Are they sleeping more than usual? Depressed teens will typically sleep more than they normally do and will often use sleep as a form of escape.
Extreme mood swings can also signal that your teen is in danger. Teens are a war room of hormones and emotions so it's natural that some emotional instability would be present. However, if you find that your teen is responding more often then not with outbursts of anger or tears, a one on one may be in order to find out how they're feeling.
They might not feel comfortable sharing their feelings with you and you need to always let them know that you are there for them to talk to. A good time to bring this up is before you feel your teen is having a problem. If the two of you are having a good day together, let them know that they can come to you with any problem they might be having. Opening dialogue when there's no sense of confrontation is best.
There are many behaviors that can be exhibited as part of teen depression. Are they having problems at school? Are they hanging out with a different crowd of friends? Has their eating habits changed? These are things that you need to pay attention to, to make sure that you have a gauge on how your teen is feeling.
The one aspect of teen depression that most parents don't want to think about is suicide. However, ignoring this possibility is dangerous and most teens will give signs that they are thinking about this. If your teen is obsessed with death, jokes about death, or makes offhanded comments about being "better off dead", you need to pay attention and investigate further. Additionally, if your teen is giving away prized possessions, this is an important red flag that would indicate you should seek help.
Teen depression can be treated and with your help your child can return to having normal teenage years. Avoid tragedy by keeping your eye on your teen's behavior and seek help if any of the warning signs appear.


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U.S. consumer bankruptcies increased 9% nationwide in 2010 from the previous year, according to the American Bankruptcy Institute (ABI), relying on data from the National Bankruptcy Research Center (NBKRC).
The data showed that the overall consumer filing total for the 2010 calendar year reached 1,530,078 compared to 1,407,788 consumer filings during 2009. Annual consumer filings have increased each year since the Bankruptcy Abuse Prevention and Consumer Prevention Act was enacted in 2005.
"The steady climb of consumer filings notwithstanding, the 2005 bankruptcy law restrictions demonstrate that families continue to turn to bankruptcy as a result of high debt burdens and stagnant income growth," notes ABI Executive Director Samuel J. Gerdano. "We expect that consumer filings will continue to rise in 2011."
NBKRC's data also revealed that the 118,146 consumer filings recorded in December 2010 represented a 4% increase from the 113,274 filings in December 2009. The December 2010 consumer filings also represented a 3% increase from the November 2010 total of 114,587.
Chapter 13 filings accounted for 30% of all consumer cases in December, a slight increase from November.
Chapter 7 of the Bankruptcy Code is available to both individual and business debtors. Its purpose is to achieve a fair distribution to creditors of the debtor's available non-exempt property. Unsecured debts not reaffirmed are discharged, providing a fresh financial start.
Chapter 11 of the Bankruptcy Code is available for both business and consumer debtors. Its purpose is to rehabilitate a business as a going concern or reorganize an individual's finances through a court-approved reorganization plan.
Chapter 12 of the Bankruptcy Code is designed to give special debt relief to a family farmer with regular income from farming.
Chapter 13 of the Bankruptcy Code is available for an individual with regular income whose debts do not exceed specific amounts. It's typically used to budget some of the debtor's future earnings under a plan through which unsecured creditors are paid in whole or in part.


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TARGETS – Malaria
Malaria is a protozoan illness bout with fever and fever, anemia and hepatosplenomegaly.
Malaria is one of the most widespread tropical parasitic diseases in the world. Spread is endemic in Africa, Asia, Oceania, Central and South America.
clinical picture is different depending on the type of malaria. Note that in humans is found mainly four types of malaria. This disease has an incubation period, which is different for different types of malaria.
One type of these four, which I already mentioned, is a tropical malaria Plasmodium falciparum with cause. It occurs most acute and severe, may furthermore also be lethal. It is dying. With this type of disease the minimum incubation period is somewhere around week, but there is the risk of disease within one year time after leaving the area in which the person resided.
As this type of clinical manifestations like malaria largely flu or viral infection. Ie main symptom is fever, which is usually accompanied by headache, pains in muscles and joints. Generally, these are the initial clinical manifestations and if the disease is not diagnosed and treated in time, can now appear serious life-threatening complications. For example, so-called. cerebral malaria, ie patient in a coma. Arises, and acute renal failure or respiratory - severe conditions that may lead to death. Overall, the most important in this disease is rapid and accurate diagnosis and appropriate treatment.


text: BUSINESS Zee eyes German b'caster's entertainment unit 8:17 AM PDT 5/5/2008 by Nyay Bhushan , Scott Roxborough FACEBOOK TWITTER EMAIL ME Bid $100 million for sportscaster, reports say Mumbai-based broadcaster Zee Telefilms has reportedly bid $100 million to acquire German broadcaster EM.Sport Media AG's entertainment division.Zee did not comment, while EM.Sport Media neither confirmed nor denied the rumored bid, first reported Thursday in Indian business paper the Economic Times. An EM.Sport Media spokesperson indicated only that the company hopes to "reach a deal sometime this year."EM.Sport Media is spinning off its kids entertainment division EM.Entertainment -- which includes a massive library of animated series, pay TV net Junior TV and Australian production studio Flying Bark Prods. -- to focus on its sports business. EM owns German sports channel DSF and live sports production company Plazamedia. Observers feel that if the acquisition goes through, then Zee -- one of India's most successful broadcasters, with a market cap of $2.3 billion -- would gain an important foothold in Europe.EM.Entertainment has long-running strategic ties with major free- and pay TV operators across Europe. After failing to find a buyer for the unit last year, EM drastically reduced its asking price, adjusting the book value of EM.Entertainment downward from about $135 million to about $60 million. Potential buyers also would likely take on EM.Entertainment's debt load, estimated at $30 million-$40 million. Nyay Bhushan reported from New Delhi; Scott Roxborough reported from Cologne, Germany. FACEBOOK TWITTER EMAIL ME Nyay Bhushan firstname.lastname@example.com Nyay_B Scott Roxborough firstname.lastname@example.com sroxborough


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Momentum (Norfolk) supports voluntary and community organisations working with children and young people in Norfolk. Our aim is to support the development of our members to build a vibrant and diverse voluntary and community sector that inspires, involves and empowers the young people that they work with.
We have a wide variety of courses, which are intended to develop the skills and knowledge of staff and volunteers working with children and young people. Our courses are open to members and non-members. Our members enjoy a substantial discount on courses. We have a subsidised training programme for those that wish to enter into youth work. We also advertise courses that you, our member groups, provide and that other organisations and individuals can access.
Momentum has a small grants programme to help you deliver high quality activities for young people, which our members can apply to. We also keep you informed of other funding opportunities. Our links with Ambition allow our members to access funding which they would otherwise not have been able to.
Momentum is an umbrella organisation with the Disclosure Barring Service allowing small organisations to undertake DBS applications for the staff and volunteers through us. Members have a reduction in the costs of DBS applications.
Our partnership with the Safer programme enables our members (under £100k) to have free or reduced cost membership.
We believe that all young people should have access to activities and opportunities. We want to support you to ensure that what you offer is accessible and inclusive for all young people. Go Do Norfolk is our free online directory of youth groups and activities for children and young people. Listings help children and young people to find out which are accessible to them. Members get a premium listing.
We act as a voice for our members in a variety of forums and provide a central point for information and guidance on a wide range of issues. We ensure that effective communication takes place between Norfolk County Council, Statutory partnerships and our member organisations that directly affect their work with children and young people.


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Combination Chemotherapy in Treating Women With Breast Cancer
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00003679
Recruitment Status : Unknown
Verified May 2007 by National Cancer Institute (NCI).
Recruitment status was: Active, not recruiting
First Posted : December 5, 2003
Last Update Posted : November 6, 2013
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether doxorubicin plus docetaxel is more effective than doxorubicin plus cyclophosphamide for breast cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of doxorubicin in combination with either docetaxel or cyclophosphamide in treating women who have previously untreated, advanced, or inflammatory breast cancer.
|Condition or disease
|Breast Cancer
|Drug: cyclophosphamide Drug: docetaxel Drug: doxorubicin hydrochloride Drug: tamoxifen citrate Procedure: conventional surgery Radiation: radiation therapy
|Phase 3
OBJECTIVES: I. Compare the efficacy (response rate) and toxicity of doxorubicin in combination with either docetaxel or cyclophosphamide as primary therapy regimens in patients with locally advanced or inflammatory breast cancer.
OUTLINE: This is a randomized, open-label, multicenter study. Patients are stratified according to participating center and operability. Patients are randomized to one of two treatment arms. Arm I: Patients receive docetaxel IV followed by doxorubicin IV once every 3 weeks. Arm II: Patients receive doxorubicin IV and cyclophosphamide IV once every 3 weeks. Patients receive a maximum of 6 courses of treatment in the absence of disease progression and unacceptable toxicity. Patients then undergo surgery (if operable) followed by more chemotherapy (if node positive), radiation therapy, and oral tamoxifen for 5 years (at the discretion of the investigator for estrogen receptor-negative patients). Patients are followed at 12, 18, and 24 months, and then annually for at least 5 years.
PROJECTED ACCRUAL: A total of 350 patients (175 per arm) will be accrued for this study.
|Study Type :
|Interventional (Clinical Trial)
|Estimated Enrollment :
|350 participants
|Primary Purpose:
|Official Title:
|A Randomised Comparative Trial of Adriamycin + Taxotere vs. Adriamycin + Cyclophosphamide as Primary Medical Therapy for Patients With Potentially Operable Breast Cancer Greater Than or Equal to 3 cm Diameter, Locally Advanced, or Inflammatory Disease
|Study Start Date :
|November 1998
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years to 60 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
DISEASE CHARACTERISTICS: Histologically proven previously untreated locally advanced or inflammatory breast cancer Potentially operable disease Tumor at least 3 cm in diameter No metastases Hormone receptor status: Not specified
PATIENT CHARACTERISTICS: Age: 18 to 60 Sex: Female Menopausal status: Not specified Performance status: ECOG 0-1 Life expectancy: Not specified Hematopoietic: Absolute neutrophil count greater than 1500/mm3 Platelet count greater than 100,000/mm3 Hemoglobin greater than 9 g/dL Hepatic: PT and aPTT normal Bilirubin normal (except in patients with benign congenital hyperbilirubinemia) AST/ALT no greater than 1.5 times upper limit of normal (ULN) Alkaline phosphatase no greater than 1.5 times ULN No active hepatitis B or C Liver biopsy normal (if positive serology for hepatitis B or C) Renal: Creatinine normal Cardiovascular: Adequate cardiac function No active cardiac disease Other: Not pregnant Fertile patients must use effective contraception No other serious medical or psychiatric disease No prior or concurrent malignancy except basal cell skin cancer or carcinoma in situ of the cervix HIV negative
PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: Not specified Endocrine therapy: Not specified Radiotherapy: Not specified Surgery: See Disease Characteristics Other: No prior therapy for breast cancer
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00003679
|United Kingdom
|C.R.C. Beatson Laboratories
|Glasgow, Scotland, United Kingdom, G61 1BD
|Study Chair:
|T.R.J. Evans
|Beatson Institute for Cancer Research - Glasgow
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
|First Posted:
|December 5, 2003 Key Record Dates
|Last Update Posted:
|November 6, 2013
|Last Verified:
|May 2007
stage IIIA breast cancer
stage IIIB breast cancer
inflammatory breast cancer
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Liposomal doxorubicin
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Antirheumatic Agents
Antineoplastic Agents, Alkylating
Alkylating Agents
Molecular Mechanisms of Pharmacological Action
Antineoplastic Agents
Myeloablative Agonists
Antibiotics, Antineoplastic
Topoisomerase II Inhibitors
Topoisomerase Inhibitors
Enzyme Inhibitors
Estrogen Antagonists
Hormone Antagonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Antineoplastic Agents, Hormonal
Selective Estrogen Receptor Modulators
Estrogen Receptor Modulators
Bone Density Conservation Agents


text:
So I just had my regular tightening of my braces and in the appointment prior to this my dentist gave me a new type of flosser to try because I told her I'd be doing my best to floss and yet some areas of my gums were still really puffy.
I mean an hour a night before bed to use those dental threaders in order to clean in-between my teeth and I still wasn't doing a good enough job.
So I substituted my regular routine of flossing using a threader with using a flosser.
The only reason I tried them was:
1. My dentist recommended it to me.
2. I found it that it literally saved me 30 mins or more a night as it's really easy to use.
3. It's called Platypus and I'm a big Phineas and Ferb fan!
What Makes This Flosser Different?
How is this flosser different than other flossers you may ask?
Well I wasn't able to use the standard flossers as the plastic arms are too thick to fit in-between my brackets and underneath the braces wire. The Platypus flosser allowed be me to get in between the brackets as it has a flattened edge that allows it to easily reach in-between the brackets.
Now I must admit, I've never been a fan of the flossers as I didn't think they could reach around the the tooth with the same ease as it had that plastic frame to hold the floss.
To my surprise, my dentist remarked how great of a job I had been doing taking care of my teeth during the appointment. I told her the only difference was that I now used the flossers instead of the standard floss.
Better Than A Toothpick Too!
The Platypus also has a toothpick like end on the opposite side of the flosser. At first I didn't like it much as I'm used to the Gum Soft-Picks which were always great at getting out any remaining food or bits stuck between my teeth.
I still use it but I've found the Platypus one to be quite useful ever since the day I ate spinach and could not for the life of me remove it from my brackets. To anyone how likes their vegetables, the Platypus has a few small spike like points on the pick end of it that allows it to easily grab hard to remove food off your brackets which is a life saver.
So if you're under going orthodontic braces treatment right now and hate to floss I definitely recommend trying the Platypus Orthodontic Flosser. In case you're looking to try them, Amazon has the best deal I've found so far to purchase them.


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yes me children 7 have. Children 1-2-3 Grown now, 4-5 High school, 6-7 6th old 10 years, 7th he baby old 7 years. Wash machine have children grown many hands help haveBeclak, have children 7 you? Wow! Laundry large - big you wash! Past 5 kids I. Grown now, all gone. Own house have again. Relief! Wipes brow. Now dogs have I. Dogs 3, fish in t a n k s have 3.
Time to knit have I (happy face)
Razors pain you;
Rivers are damp;
Acids stain you;
And drugs cause cramp.
Guns aren't lawful;
Nooses give;
Gas smells awful;
You might as well live.
Dorothy Parker,
Enough Rope
Ha! Correct! We have a winner.I like that you finger spell nice and slow!
The American writer? Author of this poem:
Thank you! Reassuring always Travis. Good friend.pretty sound! I notice you picture video slow! who are me I am exciting I think you have asl that is interesting I understand!
your welcome pleasure I am very pleasure to happy to youThank you! Reassuring always Travis. Good friend.
Not a bad day at all. I am thinking of having my husband drop me off somewhere on his way to work and try to navigate home alone.Good morning Bottesini: Seems not much snow around these days- spring is in the air! That is good news for your herd of hounds-get out of the house!
3 hours till real work: BEAT Mr Clock!
Implanted Advanced Bionics-Harmony activated Aug/07
Hi, Violet! And dogmom also. Fun with puppy!me show up why?me want see what's up here.... Interesting.
HI B-O-T-T ( you must have a sign name)Hi, Violet! And dogmom also. Fun with puppy!
Of course!HI B-O-T-T ( you must have a sign name)
interesting. how did it come about?Of course!
YouTube - You asked


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Dear Aspirants,
LAST DATE REMINDER IBPS SO 2017 RECRUITMENTToday 27 november 2017 is the last date to apply online for IBPS SO 2017 recruitment. All candidates are requested to apply online as soon as possible to avoid last moment rush.
Important Dates:
|Tentative Dates
|Online Registration including edit/modification of application of candidates
|07.11.2017 to 27.11.2017
|Payment of Application Fees- Online
|07.11.2017 to 27.11.2017
|Download of Call letter for Examination – Preliminary
|December 2017
|Online Examination – Preliminary
|30.12.2017 & 31.12.2017
|Result of Online Examination – Preliminary
|January 2018
|Download of call letters for Online Examination – Main
|January 2018
|Online Examination – Main
|Declaration of Result of Online Main Examination
|February 2018
|Download of call letters for Interview
|February 2018
|Conduct of Interview
|February 2018
|Provisional Allotment
|April 2018


text:
When I was in my first year of university and studying educational psychology I came across constructivist learning for the first time. I remember the confusion that surrounded this term and how everyone in the tutorial tried to make sense of it. I think I'm still constantly trying to make sense of it as I consider it in different teaching and learning contexts but it wasn't long into the year that I started to grasp it and love it.
The constructivists greats, the foundational researchers, are Vygotsky, Piaget, Dewey, Kolb and Montessori to name a few. All educators are familiar with these names and may feel plagued by them at times but the work of these theorists has been pivotal in shaping constructivist learning theory. Here are some of the definitions they and others have for constructivism:
"Constructivism is a learning theory found in psychology which explains how people might acquire knowledge and learn. It therefore has direct application to education. The theory suggests that humans construct knowledge and meaning from their experiences." (From The University of Sydney)
"Constructivism is a theory to explain how knowledge is constructed in the human being when information comes into contact with existing knowledge that had been developed by experiences." (From Wikipedia)
"Constructivism is basically a theory — based on observation and scientific study — about how people learn. It says that people construct their own understanding and knowledge of the world, through experiencing things and reflecting on those experiences. When we encounter something new, we have to reconcile it with our previous ideas and experience, maybe changing what we believe, or maybe discarding the new information as irrelevant." (From Concept to Classroom)
In a nutshell, constructivist learning is about the learner and how they construct their own knowledge and understanding through making connections with what they experience. This video below is a great explanation and example of constructivism in action.[youtube http://youtu.be/uP5ohML9P_w]
In lessons we have a school for years 8-10 where they get to learn more study skills and do independent study I would really like to see the constructivist learning theory played out a bit more. I'm in the process of integrating the eportfolio open source software Mahara into these lessons to help facilitate more reflection on the learning experiences that students have. I want to see them become more aware of their own learning processes and be able to improve their outcomes because of it. I can testify to the power of being aware of our learning processes through experiences we have. I myself have relished the opportunities I've had to learn about how I learn and have used that as much as possible to keep growing. I want that for my students so much too 🙂


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Trouble Shooters
Highly concentrated clarifier takes cloud causing particles that are lingering in swimming pool water and forces them to collect on the pool bottom. Once on the bottom, they can be easily removed with your vacuum
- Concentrated liquid floccing agent
- Drops small particles suspended in water to the bottom of the pool
- Compatible with all sanitizers
- For use on all pool types and surfaces
- Works faster the more cloudy the water is
- Restores water clarity
- Can help to reduce Total Dissolved Solids (TDS) in pool water
- Avoid using Superfloc Clarifier if your filter does not allow you to vacuum debris to waste
- Adjust pool pH to 7.5 or higher
- With filter running in the recirculate position, use 8 ounces per 10,000 gallons of pool water over the entire pool surface. Add 16 ounces per 10,000 gallons for severely cloudy pools.
- Discontinue pump use after 1 to 3 hours; Do not swim or allow pump to start for 24 hours
- Once suspended particles fall to the bottom of pool, slowly vacuum pool
- Some additional settling will occur for the next 48 hours after initial application
Available Sizes
- 1 qt. bottle (12 per case)


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Festive Glam Makeup Tutorial
It's Christmas party time! Get this festive party glam makeup look with Make Up Gallery cosmetics.
Posted in
Smokey Eye Makeup with Ferne McCann
Get noticed this party season with this sultry, smoky eye makeup look.
Natural Makeup Look with Ferne McCann
This natural makeup look works for everyday wear or a more subtle party look.
Party Glam with Ferne McCann
Want some ideas on how to glam up your makeup for the party season? Ferne is here to help!
Posted in
New Pound Coin, Same Amazing Value!
The new £1 coin is here from 28th March – new pound coin, same Amazing Value at Poundland!
Posted in
How To Achieve A Perfectly Winged Eyeliner
Achieve the perfect winged eyeliner with these tips, and reviews from our Make Up Gallery ambassadors!
The £10 Make Up Gallery Challenge
Our Make Up Gallery ambassadors create make up looks for only £10!
Holiday Checklist
Print out this holiday checklist for an easy shopping trip.
Posted in
Staying Safe In The Sun With Anovia
Protect your skin from harmful UVA and UVB rays with Anovia's range of trustworthy and high quality sun creams at Poundland.
Posted in
Travel Beauty Essentials
At Poundland we have a range of beauty items perfect for travelling and putting into your hand luggage. Here are our must-haves.


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For the 10 or so of you who are actually reading …
We are well into IVF with ICSI #2. Today is day six of stims. Egg retrieval will likely be on Sunday. I am feeling okay overall. I am managing to get more exercise, am paying more attention to what I eat and am generally trying to chill out a bit more. I ditched the acupuncture this time — it was a tremendous time/money suck, caused me anxiety and didn't actually help me get pregnant last time. So this time I will be indulging myself the ways that I know work for me — yoga, massage, maybe a pedicure this afternoon. And sleep, lots of sleep.
Overall, I seem to be less stressed out about this round that my wife is. Maybe it's because she knows that this is it for now — that if this doesn't work, we are going to have to switch gears and try other options. I am feeling reasonably optimistic, with healthy does of realism. I am super curious to see what happens this time, with a different protocol and medication combination. I will be waiting with baited breath to find out if I do in fact produce eggs out of my right ovary (oh, the mystery). It will also help me understand if I have a serious egg quality problem, or if last time was a fluke.
Another $8,000 is a lot of money to spend on a fact-finding mission, but that's how I am trying to think of this IVF cycle. It may result in one or more baby. Or it may not. I want to try and stay positive, without clinging to false hope.


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Back to All Fishing Gear Articles \ Uncategorized \ Local Stream Report
Local Stream Report
Despite the rain over the weekend, Nick and I still managed to land a good amout of Smallmouth and Rock Bass at a local stream. The fish were loving the brown streamers, like the carp teaser and wooly bugger. Come in to D&H to pick up some Smallmouth flies!


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Brownsville Criminal Law FAQs
I'm eligible for probation. Does that mean I'll get it?
While you may be eligible for probation, eligibility is not a sure thing. Prosecutors may decide to pursue a more severe punishment. If you believe you're eligible for probation, a good criminal lawyer can evaluate and build your case.
I'm charged with a misdemeanor. Can't I represent myself?
Even if you have the legal background required to create a strong criminal defense, we advise against it. After all, even the most skilled of surgeons don't operate on themselves. You need an impartial defender to build and defend your case.
There's a warrant out for my arrest. What should I do?
Take a deep breath and call our law office. Once we understand the circumstances surrounding the arrest warrant, we'll be in a better position to guide you. In some cases, you may be able to post bail right away. In others, it's smarter to arrange for the arrest and go from there. No matter what, ignoring the inevitable is unwise. Contact us immediately to start your defense.
I was arrested for DWI and the police confiscated my driver's license. How do I get it back?
You have 15 days to request an Administrative License Revocation (ALR) hearing. You must formally request this ALR hearing. If you miss the 15 day deadline or fail to request the hearing, you waive your right to get your driver's license back while your case is pending.


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News - update on all things Alpkit
Dan's Christmas Blocs
By Kenny Stocker | 05, Jan, 2010
In pictures
Dan Bradley took advantage of the cold conditions over the Christmas period to bag a few blocs. It is not long since Dan had some major work on his knee (no not cosmetic) so it is great to see him back on form.
Mushin - The Roaches 7c+
Joker - Plantation 8A (repeated ascent)
Froggatt Edge
Neon Dust 7c+
The Mint 400 7B+ flash
Sole Power 7C (perhaps worth 7C+)
Baslow Edge
A Fist Full of Beagles 7B+ flash
Flatworld 7c flash
Flatworld Left Hand 7c flash
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Share your thoughts about this article.


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Andy Marshall – Owner & Operator at Road Movie Mobile Cinema
After much deliberation I have decided to close down Road Movie Mobile Cinema, I have had an extremely fun and memorable 18 years and will always look back on the Road Movie days fondly. Big thanks to all the loyal clients and audience members that turned this cinematic dream into a reality. – Andy Marshall
The official shut down date will be at the end of this financial year, the 30th of June 2018.
Andy Marshall – Owner & Operator at Road Movie Mobile Cinema
Email: email@example.com
Mobile: 0421 915 346
P.O. Box 1070, Nairne
5252 South Australia
(or) contact me using the form below.


text:
Attention all Gentlemen!
Ever wondered how to pull off that "perfect" look?
Want to make sure you're always ahead in style?
Not sure how to accessorize your suit and make yourself stand out from the crowd? Which shirt to pair with the right kinds of cufflinks? Which shoes to wear, what color pocket square to pick?
Well boys, then it's time to go back to class and take some serious style advice from these sophisticated, fashion-savvy men. Satisfaction guaranteed!
Watch these Mr. Porter videos featuring model Johannes Huebl and SUITS actors Gabriel Macht and Patrick J. Adams to get inspired!
It doesn't need much more than a suit for you to look fierce and handsome. So you get your suit on and bring your a-game.


text:
Curriculum >> Key Stage 5 >> Travel and Tourism
Key Stage 5 - Travel & Tourism
you are studying A Level Travel and Tourism at MIS you can expect to learn
about the development of tourism in many different countries across the world.
This will increase your knowledge and understanding of global societies and
contribute to developing you into a global citizen.You
will investigate the travel and tourism industry and look at the changes politically,
socially, economically and technologically. You will study the importance of
tourism to national economies. You
will investigate change and development in the Tourist industry and look at the
importance of customer service and care.One
element of your course is coursework which involves planning and organising an
event which will develop many leadership, organisational and presentational
skills that are extremely valuable for later life.
and Tourism A Level can combine well with other Arts subjects and is
particularly useful for anyone considering a career in the Tourism industry or
in fact any global organisation. It provides a valuable insight into global
A Level course followed at MIS is the International Cambridge syllabus.
outline attached:
Travel & Tourism AS Year 12 Overview
Travel & Tourism A2 Year 13 Overview


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6 Fabulous Uses for Perfectly Caramelized Onions
Sweet, creamy caramelized onions are the well-earned result of many precious minutes spent stirring and stirring over medium-high heat. They can't be rushed—that'd be criminal--so you need to make sure you're doing it right. Let Test Kitchen professional Katie show you how:
Almost any dish is made better with a topping of caramelized onions, but some just really shine. Here, a few suggestions and recipes:
Keep Reading:
- Oops! What Happens When You Rush Caramelized Onions
- Our Best French Onion Soup
- Budget Recipe: French Onion Tart


text: The Policies of the School Board are our governing documents. They are updated on a regular basis and are based upon current law, directives from various state and federal agencies, and locally initiated policies. Many policies come to us as recommendations from the Montana School Boards Association but often times, the local administration and trustees will edit and adapt such policies to fit our school district. Before policies are put into place, they must have at least two 'readings' before the school board at a regularly scheduled meeting. Policy updates or edits may be made without a second hearing.