text:
Elephants die of cancer at a rate nearly four times less than humans despite their large size and similar life-span (Abegglen). Two independent studies published last month online and in the Journal of the American Medical Association indicate that additional copies of p53 and enhanced sensitivity to DNA damage may be responsible (Abegglen, Sulak). Such information provides vital information into the protective molecular mechanisms responsible for the evolution of large body size while further demonstrating the role of p53 in cancer prevention.
Proving Peto's Paradox
The lack of relationship between cancer rate and body size or age has long been a conundrum to scientists. Large animals possess far more cells than their smaller counterparts which, in addition to a longer life span, should leave them more predisposed to cancer causing genetic mutations.
Yet, in an observation known as "Peto's paradox," epidemiologist Dr. Richard Peto of the University of Oxford noted that cancer mortality rate only varies two-fold between multicellular animals (Caulin, Peto). This means mice, humans, and whales maintain a similar risk of dying from cancer despite their nearly 1000 fold difference in size and 3 fold differences in age.
Peto postulated that large, long-lived organisms such as elephants and whales must have developed intrinsic biological adaptations to protect their cells from cancer as they grow and age. While cancer protective mechanisms have already been demonstrated in long-lived rodents, the mechanism of cancer prevention in large, long-lived animals remained elusive until now (Caulin, Greaves).
Research teams lead by Dr. Joshua Schiffman, a pediatric oncologist and research scientist at the University of Utah, and Dr. Vincent Lynch, an evolutionary geneticist at the University of Chicago, sought to prove Peto's paradox in elephants after serendipitously discovering their genomes contained 20 copies of the tumor suppressive gene p53 or TP53 vs. the single pair in humans.
Known as the "guardian of the genome," the p53 protein activates DNA repair or apoptotic cell death in response to DNA damage. It is the most commonly mutated gene in human cancers and the loss of a single functional allele causes Li-Fraumeni syndrome, a disorder characterized by childhood cancers, multiple primary tumors and a lifetime cancer risk of nearly 100% (Abegglen, Vogelstein).
Lynch describes in an interview with Nature News how preparing a lecture on Peto's paradox prompted him to search the documented elephant genome for potential genetic causes.
"Right before I have the lecture, I searched the elephant genome for p53, and 20 hits came up," he said.
Schiffman specializes in pediatric cases of Li-Fraumeni syndrome. He formed a research team with evolutionary biologist Dr. Carlo Maley after Maley revealed at a conference that he identified multiple copies of TP53 in the elephant genome.
"In comparative oncology, we've learned a lot about human cancer from cancer-prone animals," Schiffman stated in an interview with the American Association for Cancer Research. "By shifting the focus to understanding why some animals are naturally cancer resistant, we could learn still more."
The Power of p53
Schiffman's team first confirmed the presence of additional copies of TP53 in the elephant genome (Abegglen). Genetic analysis of blood and skin samples from circus and zoo animals confirmed the presence of at least 20 copies of the p53 gene sequence in Asian and African elephants. One TP53 copy is genetically identical to the "canonical" or classic version found in organisms such as humans while 19 copies are "retrogenes" or modified duplicates of the classic form.
To determine if all 20 genes were capable of transcription and translation, elephant fibroblasts and peripheral blood lymphocytes were treated with DNA damaging radiation and the extracted RNA and protein assessed by Sanger sequencing, RT-PCR, and Western blot analysis. RNA and protein products of the appropriate size and sequence for canonical and p53 retrogenes were successfully detected by both teams. Schiffman's group also confirmed that a protein product produced by a specific retrogene could be phosphorylated at an active site known for conferring p53 functionality.
The most dramatic results were found when both teams assessed elephant and human cells for their cellular response to p53 activation. Schiffman's team discovered that in response to DNA damage by radiation or a chemical agent, elephant lymphocytes underwent apoptosis at twice the rate of healthy human lymphocytes and nearly five times the rate of cells from Li-Fraumeni patients. The observed increase correlated proportionally with TP53 copy number and decreased cancer risk, indicating enhanced apoptotic sensitivity is a cancer protective mechanism (Abegglen).Lynch's team also confirmed enhanced sensitivity to cell death in elephant cells. Asian and African elephant fibroblasts underwent apoptosis more robustly and at much lower doses of DNA damaging agents than the cells of their evolutionary relatives (Sulak). These data suggest that increased p53 copy number enhances apoptotic sensitivity in elephants.
DNA repair levels did not increase in response to DNA damage in either study, a fact that surprised Schiffman at first.
"We expected that DNA damage repair in elephant cells would be more efficient than human cells…but [increasing apoptosis] made sense," he told the American Association for Cancer Research. "Eliminating damaged cells could be an effective way to protect from cancer, instead of taking a chance that DNA damage will be incompletely repaired and escape into future populations."
Schiffman and his team also provided empirical evidence for Peto's paradox. By comparing the causes of death between 36 mammalian species, cancer risk was estimated to be similar regardless of body size and life span (Abegglen). The rock hyrax, a small badger which is the closest living relative to the African elephant, had an estimated cancer mortality of 1% while the cancer mortality of elephants was only 4.81%. In contrast, the cancer mortality rate of humans with no quality life insurance for cancer patients is estimated to be between 11%-25%.
Schiffman's team conjectures that enhanced sensitivity to cell death provides elephants with the necessary decrease in genetic mutations to compensate for their larger size.
As they describe in their publication, "Increasing apoptosis effectively lowers the ongoing mutation rate for the entire cell population…this 2-fold decrease in the somatic mutation rate (doubling of apoptosis) in elephants could explain the 100x increase in cell mass without cancer transformation."
Lynch and his team determined that p53 retrogene expansion evolved in correlation with increasing body size in the elephant lineage. Comparison genetic analysis between elephants and their extinct ancestors revealed elephants possess 5 more retrogenes than the smaller wooly mammoth and 16 more than an even smaller relative, the American mastodon.
The correlation in body size and p53 copy number also extends to the elephant's modern day relatives; both manatees and hyraxes only possess a single copy of p53 and are much smaller than African and Asian elephants. Lynch thus conjectures that p53 copy number evolved in conjunction with increasing size in the elephant lineage.
"These results suggest that the origin of large body sizes, long lifespans, and enhanced cancer resistance in the elephant lineage evolved at least in part through reinforcing the anti-cancer mechanisms of the major 'guardian of the genome' TP53" Lynch's team states in their papers conclusion.
A Cal Connection
Dr. Gertrude Buehring, a professor of virology at UC Berkeley School of Public Health believes these results provide further evidence of the critical role of p53 in cancer susceptibility.
"The scientific findings about p53 and DNA repair capacity in elephants are important because, in my opinion, DNA repair capacity is one of the critical aspects of relative susceptibility/resistance to human cancer" she said in a statement for this publication.
Buehring's research investigates viruses as cancer causing agents, so she questions whether elephants may have developed cancer resistance due to infections with viruses "analogous to those that are major causes of fatal human cancers, e.g. hepatitis B and C, human papilloma virus." Her most recent work provided the first link between infection with bovine leukemia virus and human breast cancer risk (Buehring 2015), if you want to rebuild it after surgery think about breast augmentation NYC.
p53's identification in the ancient elephant genome also provides additional evidence of its role in the evolution of multicellularity.
A team led by Dr. Daniel Rokhsar, a professor of molecular and cell biology as well as physics at UC Berkeley, recently sequenced the entire genome of the sea sponge, the first organism to develop more than one cell type (Srivastava 2010). By comparing gene families between the sponge and more recently evolved species, researchers investigated the evolution of gene networks necessary for cells to function as a group.
"Our hypothesis is that multicellularity and cancer are two sides of the same coin," Dr. Rokhsar said in an interview with Berkeley News.
"If you are a cell in a multicellular organism, you have to cooperate with other cells in your body, making sure that you divide when you are supposed to as part of the team. The genes that regulate this cooperation are also the ones whose disruption can cause cells to behave selfishly and grown in uncontrolled ways to the detriment of the organism."
Rokhsar's team found that sponges possess canonical p53 as well as nearly 100 other genes implicated in human cancer. Integrating information on the elephant genome could provide further evidence into how p53 expansion enabled multicellular organisms to grow in size and complexity.
Caveats and conclusions
p53 is unlikely to be the only agent responsible for enhanced cancer resistance in elephants. Additional genetic mechanisms as well as external factors such as lifestyle, environment and diet can also contribute to cancer risk.
"Elephants don't smoke, they don't drink alcohol, they are vegetarians…These are all behaviors associated with reduced cancer incidence in humans," said Buehring.
Schiffman's team would also like to confirm their results in wild elephants as only captive elephants provided the cellular and genetic material for the studies.
The mechanism by which damaged elephant cells preferentially select death over DNA repair and the role retrogenes play in p53 mediated apoptosis will also require further investigation. Most TP53 retrogenes lack introns suggesting their function may differ from traditional p53 activity. Lynch and Schiffman postulate TP53 retrogene protein products serve as "functional or nonfunctional "decoys to prevent degradation of canonical p53 (Abegglen).
Schiffman's team believes that the social and reproductive benefits of increased body size and age in elephants provided the evolutionary pressure necessary for the development of additional cancer protection. Female elephants can reproduce throughout their entire life span while older and larger members of both sexes exhibit enhanced fitness.
"The enormous mass, extended life span and reproductive advantage of older elephants would have selected for an efficient and fail-safe method for cancer suppression, "Schiffman's team conclude in their publication. "The multiple copies of TP53 and the enhanced p53-mediated apoptosis observed in elephants may have evolved to offer such cancer protection."
Schiffman and Lynch's work provides proof of Peto's paradox in large, long lived animals as well as the power of p53 and its role in cancer prevention.
As Schiffman stated in an interview with NBC News, "We certainly think we've found something intriguing."
Abegglen, L .M. et al. (2015). J. Am. Med. Assoc. http://dx.doi.org/10.1001/jama.2015.13134
Sulak, M. et al. (2015).Preprint at bioRxiv http://dx.doi.org/10.1101/028522
Greaves, M., Ermini, L. (2015). J. Am. Med. Assoc. http://dx.doi.org/10.1001/jama.2015.13153
Caulin A.F., Maley C.C. (2011).Trends Ecol Evol. 26(5), 175-182.
Peto, R. et al. (1975). Br. J. Cancer. 32(4), 411–426.
Peto, R. (1977) Paper presented at the Origins of Human Cancer, Cold Spring Harbor Conferences on Cell Proliferation. Cold Spring Harbor, NY.
Vogelstein, B., Sur, S., and Prives, C. (2010). Nature Education 3(9):6.
Buehring, G.C. et al. (2015). PLoS One. http://dx.doi.org/10.1371/journal.pone.0134304
Srivastava, M. et al. (2010). Nature. http://dx.doi.org/10.1038/nature09201.


text:
Bluegrass Farms of Ohio Inc
Agriculture / Agriculture Production
Call (740) 426-6683Directions
Get directions to thisWebsite
location on Google Maps.
location on Google Maps.
Open websiteShare
in new tab.
in new tab.
Share this business
on social media.
on social media.
We offer premium prices to Ohio farmers who contract with us to hire farmers grow pure, Identity Preserved soybeans.
Bluegrass Farms of Ohio Inc is a farm located in Jeffersonville, OH.
Service Area
Jeffersonville, OH

subset: commoncrawl


text:
Day 1: Siem Reap Arrival (-)
Welcome to Siem Reap, the
charming gateway to the famed
temples of Angkor. You will be
greeted by your local English
speaking guide, who will
accompany you to your hotel for
check in.
Take a rest from your flight at
the hotel or discover Siem Reap
on a stroll through its
beautiful pagodas and the
colorful market on your own.
This afternoon, will take you on
a journey to get the first
glimpse of the legendary Angkor
Wat. Built during the reign of
King Suryavarman II in the early
12th century, Angkor Wat is
constructed following the model
of the temple mountain
symbolizing Mount Meru, the home
of the gods. Inside the temple,
the walls are covered with stone
carvings and bas-reliefs
depicting Hindu mythology and
the wars Suryavarman II fought
during his reign. Angkor Wat is
well known for the more than
2,000 Apsara dancers decorating
the temple. Construction is
thought to have taken around
thirty years of intensive labor.
Today, Angkor Wat is figured on
Cambodia's national flag as the
temple symbolizes the soul of
the Khmer people.
Overnight in Siem Reap.
Day 2: Siem Reap (B)
After breakfast, visit the
ancient city of Angkor Thom, the
last capital of the Great Khmer
Empire under the reign of
Jayavarman VII. This city is
surrounded by an 8 m high wall
drawing a perfect square. Enter
the city through the ancient
South Gate, an impressive stone
gate carved with Elephants and
four giant faces. On each side
of the entrance path a row of 54
gods or demons is holding the
sacred Naga snake.
From here, continue to Bayon
Temple in the exact center of
the city. This 12th century
masterpiece is a study in
grandeur and is well-known for
its 54 towers with enigmatic
faces representing the 54
provinces of the Great Khmer
Empire. The Terrace of the
Elephants and the Terrace of the
Leper King are also must-visits
as they are both known for their
intricate bas-reliefs.
Later today, travel to the "gem"
of the Angkor area, the pretty
temple of Banteay Srei, which is
best viewed in the warm
afternoon light. The so-called
"Citadel of the Women" remains
the best preserved temple in
Cambodia. It displays some of
the finest examples of classical
Khmer art as this small temple
is noted for its truly
remarkable fine bas-reliefs.
Banteay Srei is unique in that
it is constructed of pink
sandstone, which is seen nowhere
else in Angkor. On the way back,
peek into Banteay Samre temple.
You will have the possibility to
stop at local communities along
the way and your guide will help
you to interact with the local
community to learn about the way
of life here. Seize the
opportunity to taste Palm Wine
and Palm Sugar (seasonal) and
other popular local produce.
Stop at the Landmine Museum
which promotes mine awareness.
Mr. Aki Ra, the museum founder,
was trained as a child soldier
during the Khmer Rouge regime
and is working today as a
de-miner. The museum serves also
as a rescue center for a number
of landmine amputee children
that Aki Ra has brought off
Phnom Penh's streets or from
impoverished rural communities.
Overnight in Siem Reap.
Day 3: Siem Reap (B/L)
Breakfast at your hotel. This
morning, enjoy a visit to the
temples of the Grand Circuit,
starting at Preah Khan Temple.
This temple was built
approximately during the same
period as Ta Prohm, and
originally served both as a
religious university and a
temple. Continue to Neak Pean,
which is unique because it is
not a temple but a sanctuary
placed in the center of an
artificial lake and connected to
four surrounding ponds exactly
at cardinals' points. Your final
visit will be to the small
temple of Ta Som, a Buddhist
temple built under Jayavarman
VII.Around noon, break up your
day with lunch at Sala Bai back
in Siem Reap, a school training
young Cambodians from poor
family backgrounds in the
principles of hospitality in
order to give them a future. You
will have plenty of
opportunities to talk to the
students as they will go on a
tour of the school after the
meal. (NOTE: Sala Bai is usually
closed during national holidays
and for the entire month of
April over the Khmer New Year
This afternoon, explore the
temples of the Small Circuit by
a local tuk tuk. The most
illustrious among these is Ta
Prohm temple, built in the mid
12th to early 13th centuries. Ta
Prohm is unique in that it has
been left largely as it was
found: overgrown by jungle trees
and vines, with many parts of
the temple crumbling to the
ground. This makes the 'Tomb
Raider Temple' one of the most
picturesque and memorable of the
Angkor temples. Your visit will
also include Banteay Kdei, a
Buddhist monastery from the late
12th Century, and Srah Srang,
also known as the "pool of
Enjoy a view of the sunset over
the Angkor ruins at one of the
Overnight in Siem Reap.
Day 4: Siem Reap -
Battambang (B/L/D)
After an early breakfast,
embark on a boat trip that will
take you on a fascinating
journey across Tonlé Sap Lake to
Battambang on a private boat.
You will pass floating villages
and flooded forests, portraying
life on this body of water that
forms Cambodia's heart. Packed
lunch will be served on board.
(NOTE: This boat trip is only
possible in the high water
period from July to December as
water levels are too low during
the dry season and transfer
times can be extremely long.
From January to June alternative
transfer by road.)
Tonight, a special visit awaits
you at Phare Ponleu Selpak.
School of Music, Visual &
Performing Arts - Phare Ponleu
Selpak combines the Arts to
provide education, support and
entertainment to the poor
communities. This project is a
success story of how
humanitarian aid work can turn
into a display of zest for life,
genuine warmth and creativity,
against all odds. A visit to one
of their circus shows will leave
you with a lasting memory of the
wonderful Cambodian people and
should not be missed when in
Battambang! After the show, a
dinner will be waiting for you
at the center. (NOTE: The circus
performance is only performed
regularly on each Monday &
Thursday. On other days private
performances are available on
request and for a supplement).
Overnight in Battambang.
Day 5: Battambang
Today have a fun morning cycling
around local villages with Soksa
Bike, a social enterprise
initiated set up to provide
scenic and informative bike
rides through the local
countryside. During the 30km
cycle tour there are plenty of
stops where you will learn how
the locals produce rice paper,
prahoc (typical Cambodian fish
paste), grolan (sticky rice
stuffed in bamboo) and other
Cambodian treats. The local
countryside is beautiful and the
Battambang area is known for the
high quality rice and also
oranges grown in the area.
In the afternoon explore another
side of Battambang. Take a
relaxing cyclo ride around the
town with an audio set providing
an informative guide to the
history of the town. Over 2½
hours sit back as your cyclo
driver takes you around the
colonial streets, markets and
temples. The audio set narrates
short anecdotes of the many
highlights in English or French.
At many you get off the cyclo
and walk around the points of
interest before moving on the
next stop.
Overnight in Battambang
Day 6: Battambang - Siem
Reap (B/L)
Breakfast at your hotel. Now
you will head to the Bamboo
Train station. The Bamboo Train
has been set up by the villagers
in order to facilitate the
transportation of goods and
persons as there are no regular
trains running any more. The
"train" itself is very basic:
one bamboo platform on 4-wheels
is activated by a small motor.
Sitting on the platform (we will
provide some cushions for your
comfort), you will travel the 8
km to the next station through
beautiful landscape and rice
paddies (depending on season of
visit). A true rollercoaster
ride without loops. (Note: the
train tracks from Battambang to
Phnom Penh are currently being
rebuilt. The long term future of
the bamboo train ride cannot be
guaranteed. Should the service
stop we will arrange alternative
This afternoon, you will be
transferred back overland to
Siem Reap (Duration 3 hours).
Upon arrival, check in to your
Overnight in Siem Reap.
Day 7: Siem Reap -
Departure (B)
Breakfast at your hotel.
Enjoy the day at leisure for
some relaxation at, some more
sightseeing or for some personal
shopping on Siem Reap's colorful
For example, visit Artisans
d'Angkor, established in 1992 in
order to support Cambodian arts
and crafts, and to help young
people find work in their local
villages by continuing the
practice of traditional arts.
Discover how wood and stone
carvings, lacquering, gilding,
and silk paintings are created.
Transfer to the airport for your
individual departure flight.
Price per Person in US DOLLARS
Hotels used in the Tours :
Include :
Exclude :
Important Notes :
Confirmations :
Remarks :
« Back to
Highlight Tours
Find other sets of packages at:
Cambodia Tours


text:
Vikram Vij
« Back to Chefs & Culinary Experts
Vikram Vij was born in India in 1964 and lived in New Delhi and Bombay until the age of 20, when he went to study, live and work in Austria. While he was there he received his chef certificate from the Salzburg Hotel Management School. Vikram moved to Canada in 1989 to work at the Banff Springs Hotel in Alberta. Vikram became a certified sommelier from the International Sommelier Guild in 2000, and is passionate about pairing wines with his cuisine.
The Vij's Group of Companies
In September 1994, Vikram opened Vij's Restaurant in Vancouver, BC. In early 1995, a passionate and a creative Meeru Dhalwala, joined him and the two began collaborating on the menu. In December 2015, Vij's moved to a new, larger location on Vancouver's Cambie Street.
Vij's Restaurant has become renowned in Vancouver, across Canada and now globally as one of the finest Indian dining experiences in the world. In 2003, New York Times food writer Mark Bittman said of Vij's that it was: "…easily among the finest Indian restaurants in the world."
In 2004, Vikram and Meeru opened a second restaurant and market called Vij's Rangoli. The market sells Vij's At Home, a line of prepackaged gourmet curries, which are based on popular recipes from Vij's Restaurant. In order to keep up with the growing demand for the packaged meals in BC, and to expand the availability of the products across Canada, a purpose-built food production facility in Surrey, BC, was constructed as the headquarters for Vij's Inspired Indian Cuisine in early 2011 where the packaged meals are cooked by hand.
As well as being available in his restaurants and in the frozen food aisles across Canada through Vij's At Home, Vij's foods are also available as part of his catering services at BC Place stadium, at Rogers Arena in Vancouver and at Whistler/Blackcomb mountains. Vij's hot and takeout foods are also sold as part of the From Our Chefs range at select Loblaw's City Markets in B.C.
In 2012, Vij's Railway Express was launched onto the streets of Vancouver. It is a mobile food truck serving up top quality Indian curries to people in downtown Vancouver for weekday lunch and private catering events. The truck was based on Vikram's travels by rail throughout India.
In June 2014, Vikram opened his third restaurant, My Shanti, based in South Surrey. The theme of the My Shanti menu is based upon Vikram's culinary travels, and includes flavours, ingredients and influences from all over the world. Within weeks of opening, My Shanti received a nomination from Air Canada's enRoute Magazine as one of Canada's Best New Restaurants. It is the second year in a row a Vij's establishment has been nominated, having won the People's Choice award in 2013 with Vij's Railway Express.
In June 2011, the BC Food Processors Association honoured Vikram with the Rising Star Award. In October 2011, he was awarded The Ernst and Young Entrepreneur of the Year award for the Pacific Region's Hospitality and Tourism category. In 2013 Vij's Railway Express was awarded the inaugural People's Choice Award from Air Canada's enRoute Magazine, as Canada's Best New Restaurant, beating out bricks and mortar establishments across the country. In April 2015, Vikram was named Chef of the Year in Vancouver Magazine's prestigious Restaurant Awards. Vij's Restaurant also received the magazine's Best Indian Award in 2015; and in 2016, My Shanti won the Gold award in that category. In 2014, My Shanti was named Best New Restaurant by the Globe and Mail. The Surrey Board of Trade named Vikram as Surrey's Business Person of the Year in 2014, and Drishti Magazine gave Vij's the Innovation in Gastronomy Award in 2015. Vikram received the Chevrolet Ingenuity Award for exceptional creativity and skill at RBC's 2015 Top 25 Canadian Immigrant Awards.
Television and Media
Vikram was a guest judge on Top Chef Canada in 2011 and 2012 and he was the guest of honour in a 2013 Top Chef Canada episode dedicated to Indian cuisine. That episode also featured the Vij's At Home packaged foods, which were sampled by the contestants. He was also a judge on the first ever Chopped Canada show, which premiered on Food Network Canada in January 2014 and he appeared weekly on CBC's Recipe to Riches which began in February of 2014.
October 2014 saw Vikram make his debut as the first Indo-Canadian Dragon on CBC's Dragons' Den. He took his place in the Den alongside esteemed entrepreneurs: Jim Treliving, Arlene Dickenson, David Chilton and Michael Wekerle. During Vikram's time in the Den, he invested in a number of new businesses and continues to work with the entrepreneurs involved.
In March 2013, Vikram hosted the world's first ever live-streamed cook-along, Cook Live With Vikram Vij. As part of Vikram's goal, to make Indian cuisine accessible to all, people were encouraged to join him live online and cook a family meal at the same time, taking instruction from an award-winning chef. They were able to Tweet questions and photos as the curry was being prepared. The first cook-along received more than 10,000 hits.
Vikram is the co-author of three cookbooks: Vij's: Elegant & Inspired Indian Cuisine, Vij's At Home: Relax, Honey and Vij's Indian: Our Stories, Spices and Cherished Recipes. He is also featured in Peter and Chris Neal's Goodness: Recipes & Stories, which celebrates "37 good food fighters from across Canada" and the 2015 release "The Butcher, The Baker, The Wine and Cheese Maker by the Sea", a book celebrating local ingredients and chefs, by Jennifer Schell.
Philanthropic Work
Vikram has long been involved with the Chef's Table Society of British Columbia, Farm Folk City Folk Organization, Ocean Wise Sustainable Seafood, UBC Farm fundraisers and the Green Table Society. As well, Vikram and Meeru's dedication to the work done at UBC resulted in the funding and opening of Vij's Kitchen, a state-of-the-art culinary learning facility at the University of British Columbia, dedicated to teaching the chefs and nutritionists of the future about ethnic food and cuisine. In 2015, Vikram also donated 120 kilos of food to The Longest Swim – Ben Lecomte's swim from Tokyo to San Francisco to raise awareness about the state of the world's oceans.
In June 2015, Vikram and Meeru received honorary Doctorates of Law from Vancouver's Simon Fraser University and in May 2016, Vikram and Meeru were honoured with Doctorates from the University of British Columbia.


text:
Use arrow keys to drive and space bar to release the cargo into the wagons.
Drive the steam train through the harsh western desert. Your goal is to get the ammo safely to the sheriff. On your way in each level adjust your speed to be able to safely pass all the obstacles. Don't speed up and try to balance your boxes and ammo in the trailer to keep them from falling out. Good luck and have fun!
Date Added: 2016-01-16
Category: Other
Played 1707 times


text:
Today we are turning up the fire for bodyweight exercises. Sharing 3 advanced core moves using an equalizer. We love using our equalizers as they help to take bodyweight exercises and core development to a whole new level and are great for progressing your workouts!
Who else is excited for The Walking Dead to come back on this Sunday?!?!
We are counting down the days! We don't watch that much television but we do have a few favorites. The Walking Dead is one of those favs! We've been hooked ever since watching the first few seasons on Netflix a few years ago. We have fallen in love with the characters on the show. We admit we are a little nervous where the second half of this season is going to go.
What is one of your favorite TV shows?
We have 3 bodyweight moves that we are upping the challenge. Some days we just grab our equalizer and challenge ourselves to moves like these here today. Equalizer is an awesome home exercise equipment for those looking to add more challenge to their fitness routine at home.
We love this piece of equipment so much we do have an affiliate with them and if you use this link and code at checkout you can save $20 –>> Get yourself an equalizer and save some money – use this code at checkout P2RTEQ20. Thanks for the support.
These are advanced moves so if trying them for first time go SLOWLY. Listen to your body.
Okay let's do this workout together!
3 advanced equalizer moves for core and upper body strength
Grab your workout buddy and do this workout with us.
*Disclaimer: make sure to consult with your doctor before trying a new workout routine. If you feel any pain or discomfort while exercising, stop.
Equipment: equalizer
Style of workout: 3 moves using equalizer
Workout focus: upper body and core
There is no magic rep number. Do what is challenging for YOU. Even a few good ones will engage your core and challenge you!
Make sure to leave us a comment down below sharing how you liked this workout. We love hearing from you. It's motivation for us!
On Instagram? Make sure to use the hashtag #ptsisters #purelytwins so we can come cheer you on!
3equalizermoves (Click to download your pdf)
Please note the equalizer pull-ups are also known as inverted rows.
Please note these moves are not safe if you have diastasis. Lori does not do these moves at the moment. She did pre-baby a few years ago.
Mantra for week – I am powerhouse!
We want you to repeat this to yourself before every workout this week. Setting a positive intention is great motivation to bring up the intensity.
Remember you are STRONG!! You have everything inside of you to be SUCCESSFUL.
Doing challenging moves like these really help to remind you that you are powerful! You can do anything if you believe and try.
Focus on your power this week. Focus on how you CAN handle anything life brings you this week.
Thanks for working out with us today.
We hope you enjoyed it! Let us know what was your favorite move. Get yourself an equalizer and save some money – use this code at checkout P2RTEQ20. Thanks for the support.
See you in the next workout.
Lori and Michelle
P.S. Want more real time workouts that burn fat and build muscle? Go here.
If you're new to Purely Twins join our tribe and get updates:
Pinterest – purelytwins
Instagram – @purelytwins and @purelytwinsfitness
Snapchat – loriandmichelle
Youtube – purelytwins and pure2rawtwins
Facebook – purelytwins
Please note that affiliate links may pop up on PT occasionally. When you click and purchase we receive a small percentage. This allows us to keep blogging! We greatly appreciate your support!


text:
NEW YORK(CBSNewYork) — The stars came out to shine at Sunday night's Golden Globe awards, but as in any contest there were hits and misses.
Life & Style magazine's Cristina Gibson told CBS2's Dana Tyler that last night's show was a study in contrast, with some stars wearing jewels and others opting for a paler look.
"There was a lot of color on the carpet, you saw red, you saw yellow, you saw a lot of jewel tones as well," she said.
Life & Style's hands down favorite was Angelina Jolie, Gibson said that her outfit stole the scene.
"She was actually wearing an Atelier Versace dress, pink silk with red accent, red purse, red lips, she just looked amazing," said Gibson.
There were plunging necklines and kicky fish tail hemlines, Charlize Theron's couture Dior gown had a little bit of everything.
"She was showing some skin. She showed some leg, she looked stunning," Gibson added.
The only male who made a fashion statement was Ricky Gervais. Gibson withheld judgement.
"I don't know if it worked for him or not. Clearly he's not afraid to take risks," she said.
But some stars didn't shine as brightly as others.
Life & Style said that actress Sara Michelle Gellar's blue and white, tie dye ball gown was a definite miss.
"She said her two-year-old daughter helped her pick it out, we're thinking maybe next time she should use a stylist," said Gibson.
But Gellar wasn't the only star who came under fire, Gibson said that Zooey Dechanel looked like she didn't know what to do with her hair.
"She had kind of weird sideburn type of thing going on. I didn't know if it was a retro 50s look but it wasnt working for her."
Even Meryl Streep wasn't safe. Streep may have won for "The Iron Lady", but Life & Style gave her basic black dress and pony tail combo a 'thumbs down'.
"I'd like to see her change it up and do something chic and different and surprise us. Its awards season. It's the globes. put your best foot forward," said Gibson.
If you didn't get enough of the red carpet on Sunday night, the Oscars are just a month away.
Which stars surprised you with their red carpet attire? Let us know in our comments section below…


text:
I inked up some new (to me) stamps and created this card. Speaking of 'inking' can you tell that my sentiment nearly ruined my card with ink blots everywhere?? I obviously over inked the stamp and applied too much pressure while stamping - yikers! Unlike myself, I took it stride and added lil "blots" everywhere with a pin and ink.
In the end I am happy I didn't crumple it up into a ball and throw it in the trash (which is quite like myself) ;)
Stamps: Simon Says Stamp! Cupcake Party and Flower Friend
Inks: Memento Rhubarb Stalk, Gray Flannel, and Potter's Clay, Versafine Onyx Black
Cardstock: Bazzill, Recollections
Bits/Bobs: We R Memory Keepers twine
Tools: Fiskars paper crimper, Star Nesties
I created this card for the following challenges: Curtain Call - "smitten", I was inspired by the colours but without the pink in the mitten because I didn't want this card too girly; Fusion - I was inspired by the sketch
Well that is it for me - stay warm out there! Cheers!


text:
Personal Injury
If you have had an injury due to an accident such as a road traffic incident, an accident at work or in a public place you can claim for compensation. If the accident is the fault of another party we can deal with your claim on your behalf.
Depending on where the accident takes place we can help you claim the compensation you deserve. Our personal injury solictors in Kent can provide you with information about the funding options and may be able to represent you on a 'no win no fee' basis.
Read more about our personal injury services below:
Contact our personal injury solicitors in Kent and East Sussex for more information on this service or to make a claim.


text:
Citruslounge 2
Hello all --
Like someone else in another thread, I have no internet access on my Xbox.
I DID, though, manage to download the 1.15 update onto my PC. What now? After putting it on a FAT32 USB stick, do I have to do anything special to get the console to see/read it?
I have looked high and low around the 'net and found nothing about this; I am hoping that someone here can help.
Thank you all ahead of time for your assistance.


text:
Friday, 27 August 2010
If I may crave your indulgence...
What is your favourite part of the site?
And your least favourite?
What one thing could I add to make it a place you would visit more often?
Are there any links you would want to see there?
Are there any characters/collection of tales you believe deserve their own section?
Are there any authors you think would fit in here? If so, give me some contact details, and I'll see what I can do.
Finally, and most importantly, does this shirt suit me?
I await any answers with interest...
Thursday, 26 August 2010
And Awwwaaayyyy We Go...
Firstly Tull continues his tales of Ray, the ever cautious robber, as he meets old friends and new during A Week of Living Dangerously.
Next up, a short and sweet tale of ladies in tight fitting costumes and impossible heels as someone decides to try to go After The FACT.
Finally, there's this trio of young girls who have been inspired by a certain group to try their hand at larceny. However, as promised by the poll results and requested by TuxedoJarod, they soon discover that Flattery Will Get You Nowhere.
One last, small thing - if you look at the pages linked above, you will see I am starting to sort out one of the biggest niggles I know there has been about my site. Bear with me - over the next few weeks, all the pages will get this new feature, but it will take time.
Have a good week,
Friday, 20 August 2010
That's better
Very nicely indeed.
Right - to the word processor!!
Friday, 6 August 2010
Before I head off...
Scenario 1
Flatmates together. Two sat on couch. First wearing uniform of white blouse, blue jacket and skirt, grey tights and blue shoes. Second wearing green jumper and pants, with green suede boots. Both tied by wrists, ankles and legs, and gagged with tape. Sitting hoping flatmate comes home after invaders have left, when they reveal she actually arrived half an hour earlier……
Scenario 2
Two housewives are sat on bed in large bedroom. Both wearing summer dresses. They've been forced to tie their own legs and ankles together with tights, stuff scarves into their mouths, tie knotted scarves into their mouths as well, and then blindfold themselves with more scarves. Now invaders are tying their hands behind their backs with tights……….
Scenario 3
Mother and daughter are in living room. Mother is wearing peasant-style blouse, long skirt with fringe and red leather boots. Daughter is wearing school uniform. Facing each other, hands tied behind back and chests/upper bodies lashed together. One of invaders is tying daughter's ankles and legs, another mothers. Third is holding older daughter with hand over mouth, waiting to tie and gag her,
Scenario 4
Woman came back from work, dressed in grey (Lady in grey as title?) Tie-neck blouse, sleeveless cardigan, knee-length skirt and boots. Laid on floor, hands and ankles bound and hogtied. Invader tying scarf over bulging mouth
Scenario 5
Woman is sat in darkened room, crying but afraid to try and speak due to packed mouth and tight white bandage over it. Her husband has been taken away, her daughters are elsewhere in the house, and the woman in the brown catsuit has not taken her eyes off her since they have been left alone. She has no idea why they are there, or what they want with her - but that's not the real problem. The real problem is the imminent arrival of her daughter's friend for the weekend...
Well I've packed my bags...
First, two tales which may be slightly off our usual topic, but still offer a good read. From Jim from Michigan, we find a tale of The Pastel Pink Rose - a prelude which, if you enjoy it, leads to more tales that we can present here.
Second, Rayron D'Olier tells us why She Asked For It.
Then, we have two continuing tales. Firstly, we offer the second part of Dottie's Arabian Nightmare - complete wth the usual embedded links to the pictures that inspired this tale.
Secondly, we present the first part of the story of The Netterton Jewels - a tale that encompass a number of my characters, includign (as always with permission) La Ciocolatta, Madame X and in this part The Dragon Queen.
KP is now on vacation, and the next postign will be week beginning 23rd August. Until then, have a good break, and i fyou have anysuggestions then post them here or send them to em at email@example.com.
Wednesday, 4 August 2010
Looking back to last month...
In which I bore the pants off people by looking back at the traffic in July.
There will be an update on Friday, folks, before I take two weeks off. In the meantime...
In July we had 2.868 visits with 12,479 page views – a small increase on the previous month, but still fairly good for a site like this. We had 1,354 unique visitors, of whom 41% were new – welcome to you all, particularly if you are from Ghana, Falkland Islands or South Africa. As for the US Watch – we still await visitors from North Dakota or Alaska...
Plenty of referring sites – but somebody please explain dogpile.com to me?
Anyway, as always when we look at the search terms some interesting combinations come up. Here are some of the cleaner ones for this month...
Gagged wearing operagloves – Family Legends
Her wrists bound over her head from a hook in the ceiling – Garage Sale
Blouse tied gagged vans garage burglars stripped – A Week In The Life
"Tied behind" skirt gagged kneel – Helping Hands
Blindfolded wendi – Morning Caller
Gagged receptionist – Work Experience
Hopping struggle gagged hop away – Just Hopping Around
Stockings tied gagged rope chair heel – The Case History
Use of blindfolds and gags with female victims – Turning The Tables
Scarf gagged mother – Bedtime story
Scarf gagged daughter – The Cat's Pyjamas
Now, in terms of which pages got the most hits in July we have:
A Wellness Day by Rayron D'Olier
A Dangerous Man by Rayron D'Olier
Bastille Day
Real Distress Time by Mordaca
Party Night
The Smoking Break by Tull
The Captive's Place by Mordaca
Perils of Snooping by Rayron D'Olier
Generations 2
Just Hopping Around by Mordaca
Dottie's Arabian Nightmare Part 1
Seventies bound 6
Not too surprising, as I expected the addition of the Rayron D'Olier section to prove popular. As for time spend on the pages...
Here Comes The Bride
Queenie and the Boxer Part 3 by Gillian B
Rough Diamond part 5 by Gillian B
Queenie and the Boxer part 2 by Gillian B
Work Experience
The Stolen Warranties by Mordaca
Queenie and the Boxer Part 1 by Gillian B
Queenie in All at Sea part 2 by Gillian B
Home Sweet Home part 5 by Gillian B
Over The Sea
Turning the Tables
Rough Diamond part 4 by Gillian B
Must have been a Gillian B fan on line.
More Friday.


text:
While the mortgage crisis undermines the entire economy, nobody is taking responsibility or accepting accountability. But plenty of people are playing the mortgage meltdown blame game. Lots of fingers point to rating agencies that gave high marks to grossly underperforming assets.
In the run-up to the mortgage crisis, companies in the business of buying securitized mortgage products leveraged themselves to the hilt, routinely buying as much as 30 times the value of their pledged collateral. Is it any wonder that we're in the mess we're in? By itself, that practice is a recipe for a credit catastrophe. But now we know that the so-called collateral was also hyped, leveraged, and not worth nearly as much as its stated value. Trusted credit rating agencies may be to blame.
Mortgage meltdown
In the absence of official government regulation, and the transparency of bookkeeping that goes hand in hand with prudent oversight, investors rely on private rating agencies to appraise assets. Had the agencies been vigilant, they would have noticed that the assets based on mortgages were losing value in a dangerously precipitous fashion. They might have surmised that housing prices don't continue to rise forever, and that, as the real estate bubble expanded, the underlying potential for further asset appreciation shrank. The catastrophic impact of the mortgage crisis could have been drastically lessened if the credit of many ailing financial institutions had been appropriately lowered by credit rating agencies.
But there's an apparent conflict of interest for the rating agencies, because the companies getting rated are the same ones that pay the rating agencies in the first place. It's like paying an appraiser to tell you how much your home is worth-which is why mortgage companies don't accept appraisals ordered by homeowners, but insist upon hiring their own appraisers. Government officials started cracking down on rating agencies this year, but it was too late to avert the mortgage crisis.
Conflicts of interest
A few months ago, three of the most influential agencies-Standard & Poor's, Moody's, and Fitch-reached a deal with the New York state attorney general's office to change how they do business. The agreement seeks to end the practice by having the issuers pay the credit-rating agencies in four installments during the rating process, not just at the end when the rating is awarded. Agencies also agreed to change how they rate mortgage lenders and their mortgage-underwriting processes, and to post ratings online for consumers to view before taking out a mortgage.
"The mortgage crisis currently facing this nation was caused, in part, by misrepresentations and misunderstanding of the true value of mortgage securities," New York Attorney General Andrew Cuomo said in an article in the Washington Post. But critics argue that changing the pay structure doesn't address the more fundamental problem of a conflict of interest between agencies and the companies they rate. They also complain that, even when agencies downgrade companies, they do it too late-by then, the problem has already exacerbated the mortgage crisis.


text:
Whilst Paracas is on the coast, it is not a beach resort per-se. Certain watersports such as wind surfing are popular here, however it is also the perfect place from which to explore southern Peru. From Paracas, the Ballestas Islands and Nazca lines are both within easy reach. The small islands can be reached within 1 ½ hours, and are referred to as Paracas's own Galapagos Islands due to the array of wildlife and sea-lions that can be spotted. The large Paracas National Reserve is also well worth a visit for the huge variety of marine birds.
Nazca would be a dusty little desert town of little interest were it not for the strange presence of massive, mysterious drawings - the famous Nazca Lines. This part of Peru's southern coastal region has a constant mild, sunny climate. The reliably clear weather permits fantastic conditions for flying, which is the best - and really the only way - to fully appreciate the dimensions of the lines. From the air, the huge geometric shapes can be seen, etched across the desert.
Discovered in 1927, they are the legacy of the Nazca people (200 BC-900 AD), a civilization about whom little is known. The lines form vast drawings of mammals, insects and deities, covering a 50 square kilometre expanse of desert floor. The hummingbird, the spider, the condor and the monkey are among the more than thirty figures that were created by the positioning of dark, sun burnt stones.
Just 1 hour south of Paracas is Ica, home to some of the largest sand dunes in the world. A good fun and exhausting day can be spent hiking the mountainous orange dunes (there are no lifts). Sand-boarding is relatively easy to pick up and is best approached as a light-hearted day of messing around. The hard work of climbing up is rewarded with thrilling sand-boarding on the way down. The technique (such as it is) involves a simple 'point-and-shoot' approach - expect lots of spills and sand everywhere.
A little less active, although certainly no less fun, is the Pisco Route. Pisco is the infamous local drink, and the tour involves a visit to Hoja Redonda Hacienda in Chincha to see how Pisco is made, a tour of the vineyards, and of course copious amounts of sampling (someone has to do it!).
|Paracas, Nazca & Ica
Showing 1 - 2 of 2 hotels in Paracas, Nazca & Ica


text:
AceShowbiz - %cJustin Bieber% is jamming with %cRascal Flatts% in a newly-debuted music video for their joint track "That Should Be Me". The 17-year-old singer filmed the video with the country music band last month after he cut his signature hair flip to give him a more mature look.
The original version of "That Should Be Me" appears in Bieber's "My World 2.0" CD, and the revamped version is recorded for "Justin Bieber: Never Say Never" soundtrack album. Of crossing genre from pop to country, he told ABC, "Music is music, and it's a universal language. It doesn't really matter what style, as long as it appeals to others and people like it, that's all that really matters."
Bieber recently appeared on the %cGary LeVox%-fronted band's ABC television concert special. The program aired on March 12, and additionally featured a behind-the-scene footage of "That Should Be Me" video. Beside the Canadian singer, Rascal Flatts were also joined by another special guest %cNatasha Bedingfield%.
Justin Bieber's "That Should Be Me" music video


text:
Crostini With Pesto, Ricotta & Beets Recipe
Simple appetizers for a holiday party. If you have a section of baguette in your freezer, crostini are the best fallback hors d'oeuvres. For toppings, just look into the fridge and pantry and use your imagination. Watch Eric Vellend demonstrate this recipe on Online TV.
1 baguette
1/4 cup basil pesto
1 cup ricotta cheese
6 pickled baby beets
Coarse sea salt
Step 1: Preheat oven to 350°F.
Step 2: Slice baguette 1/3″ thick to get 24 rounds, discarding any with big holes. Place on parchment-lined baking tray. Bake until golden at edges and firm, 15 minutes. Remove from oven and cool.
Step 3: Smear each crostini with 1/2 tsp pesto and 2 tsp ricotta.
Step 4: Drain beets and pat dry with paper towel. Slice into rounds. Dry again with paper towel.
Step 5: Top each crostini with a beet slice. Sprinkle lightly with coarse salt.
Watch Eric Vellend demonstrate this recipe on Online TV.


text: I wanted to make some kind of a "treat" for my daughter to take to class for her classmates. This is what we came up with. Usind the Cricut cartridge Everyday Paper Doll Dress Up. The pumpking and ghost were cut at 4 inches. My daughter helped and put adhesive on both sides of the blow pop. I used glue dots to adhere the eyes on the ghosts and my daughter used a black pen to give just a little color to the ghosts. I used black ink and stamped the faces on the Pumpkin using Peachy Keen Stamps pumpkin faces. These are simple and cute all in one.


text:
The Stanford Virtual Heart – Uses VR technology to explain complex congenital heart defects, which are some of the most difficult medical conditions to teach and understand. The Stanford Virtual Heart experience helps families understand their child's heart conditions, and it provides medical trainees with an immersive and engaging new way to learn about the two dozen most common and complex congenital heart anomalies.
Author: Eliane Alhadeff
Source: http://seriousgamesmarket.blogspot.ae/2017/08/stanford-medicine-pioneering-use-of-vr.html


text:
Copyright J M Painting & Decorating 2020
Based in Little Neston CH64, J M Painting & Decorating provide a reliable, high quaity painting & decorating service for clients throughout the Wirral and Cheshire West area.
My name is John and I own and run the business. My aim is to deliver a professional, stress-free service, producing results that will significantly improve your home.
From the initial surface preparation through to the final coat of paint, my experience and keen attention to detail always ensures the highest quality finish - no matter how big or small the job.
A wide variety of works are undertaken, ranging from a single feature wall to complete interior decoration.
The business is CIS (Construction Industry Scheme) registered for sub-contract work and insured for public liability up to £2,000,000.
Quotations are free and I am happy to offer advice on colour schemes and paint systems.
All work is guaranteed for 12 months.
If you would like to discuss your job requirements, please do not hesitate to give me a call.
Thank you for your interest in J M Painting & Decorating.
Couldn't be more pleased and wouldn't hesitate to recommend.
C Smeaton, CH64
Always on time, very tidy and totally reliable.
R Haggart, CH64
I think John is the most conscientious and tidiest tradesman I have ever come across.
Mr & Mrs Dale, CH66
John was punctual, totally professional and completely trustworthy.
Karen and Kate Hales, CH66
Monday - Friday 09:00 - 17:00


text:
Supreme Court hears appeal against release of Eddie Ryan Jnr
Lawyers asked to focus on habeas corpus application
The Supreme Court, which is today hearing an appeal against the release by the High Court of Limerick man Eddie Ryan (Jnr) on the grounds he had unlawfully been refused enhanced remission of sentence, has asked State lawyers to address the court on the applicability of habeas corpus (production of the body) in such cases.
The request was made by Chief Justice Susan Denham who is sitting with Mr Justice Adrian Hardiman and Mr Justice John McMenamin.
Robert Barron SC., who appears with barrister Anne-Marie Lawlor, for the State, said that in the last week two High Court judges had declined habeas corpus court inquiries under Article of the Constitution.
The High Court Judge in the Ryan appeal before the court had not only ordered an inquiry but granted the release of the prisoner.
Mr Barron said there was no right of remission. There was a discretion for the Minister to grant remission.
He said that once there was a valid conviction and a valid warrant and detention and the terms of the warrant had not expired then, he argued, it was not appropriate to have an Article 40 inquiry.
Colman Fitzgerald SC, who appears with barrister Karl Monahan, will be making the submissions of behalf of Mr Ryan.
Mr Barron said a similar order had been granted in the case of Niall Farrell (by Mr Justice Gerard Hogan) which is also under appeal.
Today's hearing is expected to last most of the day.
Ryan is the 31-year-old son of slain Limerick Gangster Eddie Ryan (senior) who was shot dead in the Moose Bar in Limerick in November 2000.
He and his brother, Kieran, were jailed in 2010 after pleading guilty to possession of a high-powered firearm and ammunition in the city.
He was sentenced to six years imprisonment in The Midlands Prison.
In a High Court application before Mr Justice Max Barrett he claimed that under the 2007 Prison Rules he was entitled to be released with a full third remission because he had been of good behaviour and participated in authorised structured activity designed to qualify him for the enhanced remission.
Judge Barrett ordered his release after finding that the Minister for Justice had erred in reaching his decision not to grant Ryan the extra remission.
He held that under Rule 59(2) the Minister was empowered to grant additional remission when a prisoner had shown good conduct by engaging in the authorised structured activities and was satisfied that, as a result, the prisoner was less likely to re-offend and would be better able to reintegrate into the community following release.
The judge said the policy behind the rule appeared to be one of seeking to incentivise and reward engagement by prisoners in a pro-active manner in voluntary activity which Mr Ryan had done.
He said Mr Ryan had engaged in some activities but not in some others and it appeared that some activities were viewed by the authorities as better than others.
The fact that some activities were so preferred by the State had never been advised to Mr Ryan.
Judge Barrett said the exercise of a jurisdiction to commute or remit sentence was a constitutionally reserved function which lay with the Minister who, the court accepted, had before him deficient information to which he ought not to have had regard.
The Minister in stating he would only exercise his power "sparingly and in the most exceptional cases" had imposed a pre-condition to and fettered the exercise of his discretion that was irrational.
The case had presented "that capriciousness, arbitrariness or, at the very least, unjustness" previously referred to by Supreme Court judges McCarthy J. and Hardiman J.
"If one winnows away any deficient information on which the Minister relied and has regard to such correct information on which he ought to have relied, there is only one possible logical conclusion the Minister could have reached…..Mr Ryan had participated in activities aimed at reducing recidivism and reintegrating into the community," Judge Barrett said.
The judge had held that a degree of remission earned but irrationally and unjustly refused tainted the balance of the term of imprisonment with illegality. The entirety of the balance of sentence remaining could not be lawful and he directed Mr Ryan be released.
A second judgment by Mr Justice Gerard Hogan, who in almost identical circumstances and for similar legal reasons released convicted IRA member Niall Farrell, has also been appealed to the Supreme Court.
Online Editors


text:
Think of a sensual massage as a slow tease ... of sexier things to come.
Sure, you can turn up the heat in your relationship by forking over a handful of cash for an expensive couple's massage. Or you can take matters into your own hands — literally — and give your partner a sensual massage right in the comfort of your own home. After all, who knows your lover's pleasure points better than you?
Massages are great for circulation, the nervous system and, in general, easing stress. But that's not all a good rubdown can do, according to Massage Therapist Jeanetta Goddette. "Most of all, massage can make us feel loved," she says. "It enhances the intimate connection we share with our partner." Even novice masseurs can give a do-it-yourself rubdown a go; just follow these steps. Read more


text:
Hi Fellow Raspberries,
I have a Bramble consisting of 5 Raspberry Pi's running Raspbian , and 1 Windows virtual machine running Raspbian. I'm currently using this cluster of computers to learn about something called MPI, and how to write code for it.
One of the things that I'd like to do is to pass a string from one computer to another, that includes 'something' that would get translated on each machine to reflect that machines underlying architecture. For example, if I invoke "uname -m" on my pi's, armv71 is returned. If I execute "uname -m" on my virtual pi I get x86_64. I'd like to end up with file path names something like /mnt/cifs/armv71/mpi_test1 and /mnt/cifs/x86_64/mpi_test1 . Any suggestions on how to do this? Thanks.


text:
Publish Rate
Rp 2,255,000
Bali Super Pass
Save up to
Rp 405,000/ Per Person
|Items to be prepared
|Private Car + Driver
|Bali Safari & Marine Park
|Bali Bird Park
|Upside Down World
|Hotel Arrival
●Private Car + Driver
Meet and Greet your private driver
●Bali Safari & Marine Park
Currently Bali's largest theme park complex. Hop on a safari bus to explore its vast site, featuring many animals living just as in the wild. Have a photo sessions with the animal as souvenir photos of yourself. Enjoy one of a kind animal shows and an unforgettable theatrical performance at the biggest indoor theatre in Bali.
●Bali Bird Park
Bali Bird Park has arguably the world's largest number of Indonesian bird species. Here, you can also see the magnificent Komodo Dragon, the only species in the world considered to survives the Jurassic period. A variety of birds live in a balinese vegetation settings and the park features many well-trained and uncage birds (which you can also take photo with), making it a popular photography spot. Many people reviewed with astonishment and actually enjoyed it even more than they had imagined!
●Upside Down World (P.29)
Upside Down World is one of the newest indoor themed facility in Bali. It offers 7 different rooms concepts such as bedroom, kitchen, dining area, living space, etc with its furniture and accessories are arranged in an upside down position. A unique and unusual concept creating an interesting sense of mystery and curiosity.
Finally, it's time to relax at Spa. We will choose the best spa depending on your accommodation area, from among the spas available at Bali Super Pass.


text:
PFRDA is the regulator for NPS. Pension Fund Regulatory and Development Authority (PFRDA) is an Authority set up by the Government of India through the PFRDA Act 2013 to promote old age income security by establishing, regulating and developing pension funds to protect the interest of subscribers to schemes of pension funds and for matters connected therewith or incidental thereto.
NPS architecture consists of NPS Trust which is entrusted with safeguarding subscribers interests, a Central Recordkeeping Agency (CRA) which maintains the data and records, Point of Presence (POP) and aggregators as collection and distribution arms, competing pension fund managers for generating and maximizing returns on investments of subscribers, custodian to take care of the assets purchased by the Fund managers and Trustee bank to manage the banking operations. The entities involved in NPS are as follows:
Following are the services offered by CRA to the Subscribers:


text:
Machinery and Railroad Accidents.
IN all cases send for the nearest surgeon; attempt very little yourself. Flush the wound with an antiseptic, then cover it with medicated gauze or similar dressing and wrap in bandage. If splint is required, apply, splint after wound is covered.
Bruises or Fractured Bones. Apply cloths saturated with an antiseptic and keep the body warm. Give hot tea, coffee or milk.
Crushed Fingers or Toes. Mold into natural shape with light touch. Do not handle them with your bare fingers; cover your fingers with gauze or clean cloth.
Crushed Hands or Feet. Do not attempt much. Tie injured part loosely in surgically clean cloth. Send for surgeon at once.
Crushed Arms or Legs. Lay patient down, cut away clothing, do not move part. Wrap with clean gauze. Wrap several sheets of absorbent cotton over this; bandage over all to hold dressing firm.
Crushed Chest or Lower Part of Body. Dress any wounds with clean gauze and apply warmth until surgeon arrives.
Any statements made on this site have not been evaluated by the FDA
and are not intended to diagnose, treat or cure any disease or condition.
Always consult your professional health care provider.
copyright 2005, J. Crow Company, New Ipswich NH 03071
Privacy Policy for Household Physician
Email Us


text:
The families of two men who were struck and killed by a Porsche in Fort Lauderdale earlier this year have reached a $2.2 million settlement in the case.
Mackendy Jules and Samuel Martindale were killed in the June 13th crash in the 500 block of W. Broward Boulevard. Alyza Rachel Russell, 22, was arrested on DUI manslaughter charges in the crash.
According to police, a toxicology report shows Russell was more than twice the legal alcohol limit when she tried to make a left turn in her mother's Porsche Panamera but lost control and drove into a nearby parking lot, killing the two men.
Russell was arrested and later released on $450,000 bond. The criminal case is still pending.
Jules, 30, and Martindale, 35, were homeless and were regulars at a nonprofit center that helps the homeless, the Sun-Sentinel reported.
David Nunez, who represents Martindale's family, said the family didn't want to go through a drawn-out lawsuit.
"A human life is priceless," Nuñez told the Sun-Sentinel. "But when you put things in perspective, it was in the best interest of the family to take this settlement and turn this page and move forward."
Robert Zarco, an attorney who represented Russell, confirmed the deal.
"The family is very sorry about the incident, a tragic accident that affected many lives, including that of Alyza Russell," he said. "However the family has, in fact, entered into a fair and reasonable settlement with the family of the victims."
More NBC6.com Stories:


text:
Do you have an upcoming IT Project you're dreading? Are you unsure of how to begin the process?
Unless you are fortunate enough to have an experienced team complete with project manager, business / functional analysts and subject matter experts on standby to facilitate your requirements, IT projects can be a daunting prospect. The project team must have a thorough understanding of the business, the technology being replaced or upgraded, the circumstance driving the change and finally the options available to provide the solution. All in all it is potentially a very intense, lengthy process and one that will almost definitely distract from business as usual.
Clarity IT Advisors will assist you with your IT project, from inception to delivery and beyond. With our in depth knowledge we'll share your vision for change and inspire you with the possibilities available to you.
We'll begin by identifying the scope of the project and ensuring that we have a shared vision of what success looks like. We'll work with the people in your business to ensure that we have a clear understanding of your situation and requirements, including a list of your priorities. Next we'll present you with the possible solutions, detailing what each option can provide and what it means to you and your business. Once the solution has been fully agreed we'll set to work on implementation. At this point you may expect that our role would end but we'll continue to monitor progress and provide assistance until you are confident with the new solution.
We have the skills and capabilities to follow project management rigour or provide a 'just do it' solution, the choice is yours and we will flex our style to meet your needs. Our IT knowledge and experience means that your business will be presented with the right solution allowing you to concentrate on running your business.
Ensure your project is successful, in budget and delivered on time by calling Clarity IT Advisors. Our Project managers have over 20 years of experience in IT and can steer you and your organisation away from the pitfalls that await you and make sure you achieve your goals.


text:
Romantic hotels
Shakespeare's England is packed with romantic hotels ideal for a romantic weekend away in Warwickshire with your loved one. Pamper your partner in one of the most romantic parts of the country, the birthplace of the world's greatest playwright William Shakespeare.
From luxury spa hotels, boutique B&B's, to historic Tudor hotels, there is much to choose from in order to find your perfect romantic hotel is right here in rural Warwickshire.
As the official tourist destination guide to Warwickshire, why not browse the Where to Stay section of the Shakespeare's England website to find the perfect romantic hotel in Warwickshire.


text:
pour une
bonne nuit
Discover Hotel Première Classe Paris Ouest - Gennevilliers Barbanniers, a budget establishment near the capital and la Défense and de Roissy - CDG neighborhoods.
92230 Gennevilliers France
Located in a pleasant environment near the Sévines Park and the Chanteraines Regional Park, our Première Classe Hotel is ideal for all your travel to the capital since it is easily accessible from Paris, la Défense and the Roissy Charles-de-Gaulle Airport. Its 111 recently renovated rooms are all air conditioned offering a bright, functional and comfortable combining the warmth of wood and textiles with modern materials.
All rooms now have an en-suite bathroom (shower cubicle, sink and toilet), the rooms also have a modern amenities including a flat-screen TV and Free Wi-Fi. You can leave your car in the hotel parking lot and use public transit to make your way around: the Gennevilliers RER C train station is just 2 minutes from the hotel while buses 178 and 166 stop in front of the hotel. A bit farther down the street at the Stade de France Stadium, you will also find the tramway and metro line 13.
Look no further, book direct. Our best prices are available at Premiereclasse.com.
The 111 rooms of the hotel are soundproofed (double windows) and air conditioned (individually adjustable system. Recently renovated, all rooms offer a bright living space, combining the warmth of wood and textiles with modern materials. They also all have a desk, private shower, toilet and LCD TV (with Canal+ and TNT channel) as well as Free Wi-Fi.
Beyond single and double beds, some of our rooms also have an overhead bunk to accommodate a third person at no extra charge. This is an advantageous solution for people traveling with a child, or even families since we also have baby cribs available at reception. In addition, please note that 4 specially adapted rooms are available for the comfort of people with reduced mobility.
The all-you-can-eat breakfast buffet at Hotel Première Classe Paris Ouest - Gennevilliers Barbanniers is only €5.90 (and half price for children under age 10). Fill up on vitamins every morning with our croissants, buns, whole wheat bread, brioche, baguettes, Breton bar, corn flakes, butter, honey, jams, fruit compotes, plain yogurts, orange juice and mixed fruit juices, coffee, chocolate, milk and tea.
92230 Gennevilliers
Phone: +33 1 40 85 16 19
Fax: +33 1 40 85 00 21
We wanted somewhere cheap to stay as our intention was to stay just one night and use this as a base to e ...read more >
Staff was nice, speak english and don't bother you. Cleanliness was perfectly fine. Room for one person ...read more >
The rooms were small and semi clean, the pictures made it look so much bigger than it actually was. It ad ...read more >
I was not expecting luxury but it is annoying when the room looks nothing like the rooms on the website o ...read more >
Room from EUR 39


text:
System Requirements¶
To access and work with the AIMMS Cloud Platform the customer's network must meet the following requirements:
- URLs for the Production and Non-Production set-up and optional AIMMS Cloud Platform Application Databases must be white-listed on all network access control and security systems for the customer network.
- Use of Web Sockets must be permitted on the customer network.
- Sufficient network bandwidth to run typical web-applications and transfer data files: at least 4 Mbit/s per user.
- Sufficiently powerful client device. Apps with the Windows UI require Windows 7 or higher, at least 8 GB of RAM, at least 10 GB of free disk space. Apps with the new Web User Interface require a 'browser device' with at least 8 GB of RAM.
- Internet browser: recent Chrome version, Internet Explorer 11 or Edge (WebUI apps) or recent Safari version (iOS devices). Apps with the Windows User Interface will work on Internet Explorer 8+.
Last Updated: January, 2020


text:
Mad about machinery, FG Machinery keeps you up to date with all the latest agricultural machinery developments - everything from quads to Quadtracs.
FG Livestock is the home of all livestock related content from the Farmers Guardian weekly magazine and FGInsight.com website.
This campaign aims to raise awareness of the diverse career opportunities available in the sector to non farming audiences.
FG's farm life hub brings you everything from farm profiles, recipes and young farmers, to history, charity and health and wellness, we have rural life covered.
This series explores sustainable farming, the benefits and how to implement best practices at grass roots level.
All about arable: FG Arable aims to keep you up to date with all the latest news, views, insight and information from the arable sector.
This series is dedicated to exploring the innovative strides being made by Cogent UK in Dairy Breed Technology.
Leaving the EU brings challenges, opportunities and unanswered questions for farming. Let Farmers Guardian help you navigate these unchartered waters with this dedicated Brexit hub.
This ambassador programme follows a series of proactive beef and dairy farmers on their journey towards a disease-free future.
FG's business section keeps you abreast of all the latest market developments, including analysis of prices and data across all the key sectors.


text:
This story was delivered to BI Intelligence Apps and Platforms Briefing subscribers. To learn more and subscribe, please click here.
Apps that use Apple's ARKit have been installed more than 3 million times since iOS 11 was released on September 19, according to data from Sensor Tower. ARKit, Apple's augmented reality (AR) framework, only works with Apple's newest OS.
Less than a month since the launch of iOS 11, games are already taking a notable lead in the ARKit-only apps category, according to the report. ARKit-only apps are built specifically for this AR technology, though some may use elements of ARKit for added functionality. Here's how the ARKit-only app market is shaking out in its earliest days:
- The mobile game category is the leader in ARKit-only apps among both developers and consumers. Games accounted for 35% of all available ARKit-only apps globally, 52% of all ARKit-only app downloads, and 62% of total ARKit-only revenue.
- Utilities and entertainment ARKit-only apps are the second- and third-largest categories, accounting for 19% and 11% of available ARKit-only apps, respectively.
While 3 million downloads may be just a blip on the radar in the grand scheme of things — there were over 90 billion app downloads across iOS and Google Play in 2016 — downloads of AR-oriented apps are expected to grow. As AR-enabled smartphones start to account for a larger share of all smartphones, developers make more AR-oriented content, and consumers adapt to this new technology, the revenue from AR gaming apps is expected to reach $8.9 billion by 2021, up from $89 million in 2016, according to a forecast from Technavio.
New VR headsets like the Oculus Rift and the HTC Vive debuted amid great consumer anticipation, while VR content launches kept pace, with Batman: Arkham VR and Chair In A Room garnering encouraging download totals. At the same time, industry groups and conferences brought developers, investors, and content producers together, helping to further ramp up buzz in this nascent space.
VR headset shipments will continue to grow in the years ahead, driven by the introduction of new content that will appeal to a broad swath of users.
Jessica Smith, research analyst for BI Intelligence, has compiled a detailed report on virtual reality that:
- Identifies the major players in today's VR hardware and platform markets.
- Estimates future growth of each of the major VR categories.
- Explores barriers to mass market consumer adoption for each of the VR hardware categories.
- Considers how developer sentiment is driving the growth of various platforms.
- Assesses how the market will shake out over the next five years in terms of size and the success of various VR hardware categories.
To get the full report. subscribe to an All-Access pass to BI Intelligence and gain immediate access to this report and more than 250 other expertly researched reports. As an added bonus, you'll also gain access to all future reports and daily newsletters to ensure you stay ahead of the curve and benefit personally and professionally. » Learn More Now
You can also purchase and download the full report from our research store.


text:
A resident camp for boys and girls,
ages 6-13 in beautiful Prescott, Arizona
ages 6-13 in beautiful Prescott, Arizona
Sundays at Friendly Pines are very special days. Instead of going to activity periods, everyone participates in a camp-wide and exciting theme day! Some of our theme days include:
After dinner each day, Friendly Pines Camp gathers for an evening activity. This activity is usually one that involves the entire camp, and is different on every night of the session. Many of these activities are long-standing Friendly Pines' traditions. Some of our evening activities include:
Also, every cabin group goes on an overnight camp out at least once during the session. The groups camp right on the property. They will cook their dinner, play some games until nightfall, enjoy a campfire and s'mores, cook breakfast in the morning, and be back in camp in time for the next day's activities. We provide large wall tents to sleep in; however, when the nights are warm and clear (which they are most of the time), campers love to sleep right under the stars.


text:
A really easy Git workflow for site development
Stop with that FTP non-sense and setup a real development workflow using Git.*
I'm fairly new to Git. I've only been using it in a team setting for about 6 months. But it has quickly become an indispensable tool. At work, the Git environment is already setup when I get to a project. I just clone the repo to my local machine and off I go. Each push I do goes up to the origin repo and automatically gets deployed to a live test server and domain. It's simple and amazingly helpful for a couple of reasons.
- I instantly get to see my work on a live server instead of just on my local server. Deployment is taken care of.
- I can share a link to the password-protected preview site with the client for review. And all by just typing: 'git push' It's like magic, basically.
Except, it's not magic. I'm going to show you really quickly how to get a simplified version of the same git workflow setup for yourself. This is what I use for my personal development projects.
The philosophy
The actual steps to doing this are pretty easy, the harder part is wrapping your head around the idea of how it works. Really, all you're doing is initiating a bare repo on your server that you will only use to push/pull from. You need a bare repo for this because it will avoid a ton of conflicts later. Git was created to help you avoid conflicts! A bare repo doesn't maintain a working tree, meaning you won't be making commits to it directly like your local repo. Again, you will only push to and pull from this bare repo.
These are the steps to get your git workflow flowing:
- Create a bare repository on your remote server, which you will push to from local and pull from for the live preview site.
- Clone the bare repository to your local development environment.
- Clone the bare repository to another directory on your remote server that's mapped to a preview domain
I'm going to assume you have the following:
- A remote server with Git installed
- A local development environment with Git installed
- A domain you can use for the preview site
- A basic knowledge of Git (if not, go here: http://git-scm.com/)
Regarding Git on the server
In most cases, if you're using a shared server Git will probably already be installed. Those of us newer to developing for the web often start by buying shared server space. This is what I'm doing. I use Dreamhost (because it's cheap), which already has Git installed for me. What I'm saying is, if you're using shared hosting space (Dreamhost, Bluehost, etc) then you're probably ok. Check your server's documentation for this or contact them to inquire.
Let's get to it…
1. Create a bare repository on your remote server
SSH into your server.
ssh firstname.lastname@example.com You'll then be asked for your password
You may have to configure this stuff if you've never ssh'ed into your server before. That's not covered here. You can also do this step via FTP, but we're trying to get away from FTP, remember.
Create a new directory called 'bare'. This is where you'll set up all bare repos for each site you make. You'll need a bare repo for every site you create in the future.
mkdir bare
cd bare
Just type in
git to make sure Git is installed. If you get a status report, all is good. (Later, you can customize your terminal prompt in a way that will always show you if you're in a repo, what branch you're in and if you're in a clean or dirty state. Look into it when you get to that point. It's really helpful.)
Now, create the bare repo using the domain name of your eventual site suffixed with .git. So if your domain is radwebsite.com, you'd do:
git init --bare radwebsite.git
That's it, you now have a bare repo setup and ready to go.
2. Clone the bare repo to your local machine
On your computer create a directory called git in your user directory. On a mac, that's something like Users/Sally/git
Open terminal, cd into the git directory you just created and clone the bare repo
git clone firstname.lastname@example.com/bare:radwebsite.git
There's some fancy stuff happening in the above command. This works similar to an ssh but with a few minor differences. Basically, you're telling git where to clone from and the name of the repo you want to clone.
Now, within the git directory you will have another directory called 'radwebsite' (or whatever your repo was named). Make some changes, like add an index.html then do a commit of those changes.
Back at the terminal after you've made any changes run the following commands
git status – will list tracked changes available for commit
git add -A – adds all the changed files
git commit -m "message about the changes made" – commits the changes
After you've committed some changes push your repo back to the server
git push
3. Pull your repo into a live directory
The last step in this process is pulling your repo into a live directory so you can view your beautiful site online.
SSH into your server that serves up your preview site.
CD into the directory your domain points to. In a lot of cases, your hosting company will create a directory with the same name as your domain. So if they're hosting myradwebsite.com you'll have a directory on your server called myradwebsite. Everything in that directory is the website shown at myradwebsite.com. cd into this directory. We're going to pull from the bare repo into this directory, essentially copying all those files to your live site.
git clone ../git:myradwebsite.git
That acts as your first pull. Every time after the first time simply run git pull and anything you've pushed from local to the bare repo will be copied to the live site
That's it. You're all set up. Now, just keep coding locally. After you push new changes from local to the bare repo you'll just need to git pull changes into the live site directory on the server.
This post ended up being a lot of words, but the overall process is very simple. I hope you agree. And I hope it makes your life a lot easier. I know it has for me.
* People will say, don't use Git for deployment. But it works great for test deployments during the development process. And that's the idea of what we're doing here. So ignore those people.


text:
What ever the course of our lives, we should recieve them as the highest gift from the hand of God, in which equally reposed the power to do nothing whatever for us. Indeed, we should accept misfortune not only in thanks, but in infinite gratitude to Providence, which by such means detaches us from an excessive love for Earthly things and elevates our minds to the celestial and divine.
Cite this Page: Citation


text:
About us
K. P. InfoTech was established in the year 2000.
15 Year of Experience in Providing Services for Corporate Branding.
We have professional team for each our different Services.
Digital Services
- SEO read more
- Social Media Management read more
- Website Design read more
- Animation read more
Other Services
- Remote Staffing read more
- Business Consulting read more
- Content Writing read more
- Mobile App Mobile App
Get in Touch
Phone- +91 829 16 10104
Email: firstname.lastname@example.com
Website: www.kpinfotech.co.in
Download: E - Catalog


text:
PlateSpin Migrate is a Windows application that runs on server operating systems. Its functionality depends on several software components, including the Microsoft Internet Information Services (IIS) Web server software along with its feature extension modules, the ASP.NET Web application framework, the Microsoft .NET Framework library and runtime, as well as a dedicated Microsoft SQL Server database instance.
For trouble-free installation and operation of PlateSpin Migrate, you should familiarize with system requirements and take time to plan your installation.
This section provides information about installing PlateSpin Migrate 9.3.
IMPORTANT: Upgrading from previous versions has been disabled in this release. It will be re-enabled in future releases.


text:
Publicações científicas
Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria
Carmen Unzu (1), Ana Sampedro (1), Itsaso Mauleón (1), Lucía Vanrell (1), Juan Dubrot (1), Rafael Enríquez de Salamanca (2), Gloria González-Aseguinolaza (1), Ignacio Melero (1), Jesús Prieto (1) and Antonio Fontanellas (1)
(1) Division of Gene Therapy and Hepatology, Centre for Applied Medical Research (CIMA), University of Navarra, Avda. Pio XII, 55, 31008 Pamplona, Spain
(2) Research Center, Hospital Universitario 12 de Octubre, Madrid, Spain
Revisão:Journal of Hepatology
Data: 23/Set/2009Imunologia e Imunoterapia [ES] Hepatologia
Acute intermittent porphyria (AIP) is characterized by hepatic porphobilinogen deaminase (PBGD) deficiency resulting in a marked overproduction of presumably toxic porphyrin precursors. Our study aimed to assess the protective effects of bone marrow transplantation or PBGD gene transfer into the liver against phenotypic manifestations of acute porphyria attack induced in an AIP murine model.
Lethally irradiated AIP mice were intravenously injected with 5x10(6) nucleated bone marrow cells from wild-type or AIP donor mice. To achieve liver gene transfer, AIP mice received by hydrodynamic injection plasmids expressing human PBGD or luciferase driven by a liver-specific promoter.
Erythrocyte PBGD activity increased 2.4-fold in AIP mice receiving bone marrow cells from normal animals. Nevertheless, phenobarbital administration in these mice reproduced key features of acute attacks, such as massively increased urinary porphyrin precursor excretion and decreased motor coordination. Hepatic PBGD activity increased 2.2-fold after hydrodynamic injection of therapeutic plasmid. Mice injected with the luciferase control plasmid showed a high excretion of porphyrin precursors after phenobarbital administration whereas just a small increase was observed in AIP mice injected with the PBGD plasmid. Furthermore, motor disturbance was almost completely abolished in AIP mice treated with the therapeutic plasmid.
PBGD deficiency in erythroid tissue is not associated with phenotypic manifestations of acute porphyria. In contrast, PBGD over-expression in hepatocytes, albeit in a low proportion, reduced precursor accumulation, which is the hallmark of acute porphyric attacks. Liver-directed gene therapy might offer an alternative to liver transplantation applicable in patients with severe and recurrent manifestations.
CITAÇÃO DO ARTIGO J Hepatol. 2010 Mar;52(3):417-24
talvezlhe interesse
A Clínica é o hospital privado com maiores recursos tecnológicos de Espanha, tudo num único centro.
Os profissionais da Clínica realizam um trabalho contínuo de investigação e formação, sempre em benefício do paciente.
Conheça porque é que somos diferentes em relação a outros centros sanitários. Qualidade, rapidez, comodidade e resultados.


text:
Keeping Parts On Hand
Before something breaks on the boat or there needs to be some type of new item because another is outdated, you need to make sure that you have replacement parts for boats on board. You can sometimes order parts online that you think that you'll need or want, or you can find parts from boats that are for sale by individuals who are trying to make money. When you get the parts for the boat, you need to examine them to ensure that they are in proper working condition as you don't want to use something that is just as bad as what you have or that will break in a few months after putting it on the boat. Some of the replacement items that you get should be new, such as life vests, filters for the oil and lights to ensure that they will work for an extended time while providing safety for those who are on the vessel.
The lights for the boat are often the most common thing that you would need to get replaced. You need to check the lights on a regular basis as these are often required if you are boating at night. There are usually red lights on one side and green ones on the other to alert other boats of your location in the water. The props and parts for the motor should also be examined on a routine basis. The filters for the oil and other fluids need to be checked just like with a car to ensure that the mechanical components are operating in the proper fashion.
A cover or a top of some kind will help to protect the interior of the boat and the outside while it's not in use. If you live in an area that sees a lot of rain or if you only plan on getting the boat out on a few occasions, then it's best to get a cover for the boat instead of letting it sit in the sun all day. Sometimes, the seats might get torn or ruined from the amount of water that gets onto the boat. Invest in material that is waterproof and in seats that are comfortable with plenty of foam material inside so that they last longer.


text:
It is impossible
It is not necessary to frighten anybody, but it is necessary to tell the truth that occurs.
It is impossible to hide and close eyes.
It is impossible to continue fiddle while Rome burns.
It is necessary to look at the world rationally.
if there was no medicine, OST only to feast at last, and there come what may! But if there is a medicine, why to move to sufferings when it is possible to go already today some other way And it is not necessary practically, anything.
Only to turn vnimascientific research institute on interaction between us.
We should execute a bible appeal love near as itself about which tell all religions and against which anybody and does not object..


text:
Mahesh Babu at Ai audio launch
Director Shankar's upcoming film Ai has been in headlines for obvious reasons. The audio launch of the film, which is slated to take place on September 15 is getting bigger day by day. Hollywood actor Arnold Schwarzenegger will fly down to Chennai to attend the launch.
We also hear that Rajinikanth and director K.S. Ravikumar will be taking a break from Lingaa shooting to attend this event. Also, sources say that Kamal Haasan has also agreed to be a part of this audio launch. The latest guest to join the list is Telugu actor Mahesh Babu.
Sony Music who has bagged the audio rights of the film is planning to release a single before the official audio launch to create more hype.


text:
The Nike Drop Type Mid LX Releases In "Dusty Olive"
51 mins 0 by Jovani Hernandez
Color: Black/Chutney
Style: 136008-071
Release Date: June 1998
Though not the usual colorway seen on Air Jordans, these buttery low cut Chutney XIII's are a great casual sneaker to wear, when you don't feel like putting on "heat". These lowtops don't feature a hologram on the ankle, but a gold Jumpman instead. Pics via Kixclusive


text:
Agustina Ros is a young artist who seeks with glass to combine the time of the trade, the sensitivity of art and the resolution of design. Born in Misiones, Argentina, she currently resides in Barcelona, city that she chose to open her own studio with international projection.
Her pieces in contemporary jewelry are made in borosilicate glass, modeled and blown by the technique of flameworking. Some are worked with fine metal fuming (gold and silver), and by carving and polishing generates faceted looking for light reflection.


text:
The Kangaroo Point Holiday Apartments offer 3.5 star and 4 star family, self contained apartments with a large variety of features, at affordable prices.
Our One, Two and Four bedroom fully self-contained serviced apartments are conveniently located in Kangaroo Point close to Brisbane City, South Bank and Fortitude Valley and are perfect for daily, weekly, monthly or extended longterm stay.
- air conditioning and heating
- fully equipped kitchen with stove, microwave, fridge and dining table
- spacious living room with colour TV
- Foxtel
- Laundry facilities available
- Free Wifi
- swimming pool
- bbq area
- 1, 2 or 4 bedroom apartments
- iron and ironing board
- hair dryers
- private bathrooms with showers
- some with baths
- 1 disabled apartment
- modern furnishing
- air conditioning and heating
- iron and ironing boards
- bath and shower
- fully equipped kitchen with dishwasher
- laundry with washing machine and dryers
- large balcony with outdoor dining setting
- foxtel
- direct dial phone
- internet connection
- security cameras
- intercom systems
- 2 disabled apartments
- heated pool
- bbq area
- 2 bedroom apartments


text:
At the start of October 2018, I started an online data science bootcamp course to begin my transition from education into the world of computers, technology, and heftier paychecks. Education has, for the last 3 years, been a roller coaster. At times, it would ignite my passion to leave the field altogether as I became… Continue reading The Switch
Category: Teaching
The Void of Education: What Matters
Every year, I am faced with a challenge familiar to many educators across the US and even around the globe--I have to convince my class that education matters. To some, this may seem redundant, especially for high school students who need to graduate, but any educator instinctively knows that a student will learn best when… Continue reading The Void of Education: What Matters
Advice for Neophytes
As a profession, teachers have one of the biggest and most diverse clientele base to serve to. Some teach highly autistic children (a very admirable choice) while some tend to focus on more gifted students—a more, ahem, "typical" choice. Regardless of their selection or position, many teachers can easily empathize with a plethora of different… Continue reading Advice for Neophytes