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I loved my original Motorola Razr phone. So when Verizon announced the new Motorola Droid Razr, I was anxious to take a look.
Since its inception in 2007, the iPhone has been exclusive to AT&T. So it is not surprising that recent news of the iPhone becoming available on the Verizon network piqued the interest of many. So many, in fact, that Verizon Wireless announced that the number of iPhones it sold in the first two hours of availability exceeded the one-day total for any other device's debut in the carrier's history.
Now AT&T is fighting back. Ric Whitman, the AT&T Area Retail Sales Manager, gave me a list of reasons why the iPhone on AT&T is better than the iPhone on Verizon:
1. On the AT&T iPhone you can do simultaneous voice and data. On the Verizon iPhone you cannot.
2. The AT&T iPhone has an International advantage. It can be used in 220 different countries. The Verizon iPhone cannot.
3. AT&T has over 23,000 hot spots where AT&T subscribers can get free wireless access.
4. AT&T has the lowest priced iPhone offering the 8GB 3GS for $49.
5. AT&T has the nation's fastest mobile broadband
So let's look at these in depth to help those of you who want an iPhone decide which carrier to use.
The first point is well taken. Only the AT&T iPhone will allow you to surf the web or get directions while talking on the phone. If you are a heavy data user, this might be a big drawback, but most average users will only encounter an occasional situation of this type.
The second point is also very valid. The AT&T iPhone is a GSM phone which can be used internationally. The Verizon iPhone is a CDMA phone that will not be able to be used in most overseas countries. So if you plan to travel internationally, AT&T will be a better choice. Again, however, this will be important to only a small number of users.
AT&T hot spots are certainly a plus for AT&T users. They can not only give you faster data access, but they take some of the burden off the mobile network. AT&T has set them up in Starbuck's and other establishments and also has many in a variety of Metro areas.
The cost of the current iPhone is the same at both AT&T and Verizon. $199 for the 16GB model and $299 for the 32 GB model, along with a two-year contract. So to be able to get an iPhone for $49 with a two-year contract is a big savings. This is sure to appeal to users who want to get in cheaply. But by purchasing this older model, they will be giving up the iPhone 4's retina display, dual cameras, HD video, and other perks. Although this older 3GS can run iOS 4, the latest operating system, some capabilities like the improved accessibility options will not be available.
Now we get to the last point. While AT&T may have the nation's fastest access, it doesn't do you much good if you don't have good or fast coverage in the area where you live. This is the situation in this area of North Carolina. When I purchased my first iPhone in 2008, our area was on AT&T's slower EDGE network. Although promises of an upgrade to the faster 3G network were made, AT&T never delivered. We are still on the slower EDGE network. So if you compare an AT&T iPhone to a Verizon iPhone in our area, the data access will be currently be much slower on the AT&T iPhone. AT&T again promises 3G in our area soon. And for the first time they have stated this in writing. Crystal Prince, AT&T's public relations representative, writes in an email, "I've checked with our Network team regarding plans for 3G in Pinehurst-Southern Pines-Aberdeen. Rest assured it's on the way. The team is working very hard to get everything in place for a launch soon so we expect that it will in fact be up by EOY (end of year) 2011."
Both Ric and Crystal also say that AT&T is working on covering "dead spots" that they now have in our area including many in the Pinehurst-to-Raleigh corridor. I know this to be a fact as they are constantly adding new equipment and towers, but again, "when" this will all be accomplished is an important question.
Two other recent offerings and announcements show that AT&T is really trying to get your business. This week, they announced that AT&T customers will now get free calls to any cellphone in America. The only requirement is that you have certain voice plans that include AT&T's unlimited texting plan. That texting plan is $20 a month for individuals or $30 for families.
AT&T is also offering free microcells to current customers. These are small $199 devices that hook up to the broadband in a home or office and pull the 3G signal from the Internet. If you don't get good cell reception indoors, this is the answer to your problem. Although, not highly publicized, these free microcells are available to most AT&T customers with an additional year on their contract.
If you are ready to move into the iPhone world, you have to make a decision between AT&T and Verizon. You cannot use a Verizon iPhone at AT&T or vice versa, so you will be making a sizeable investment. While Verizon has much better and faster coverage in our area, some are worried that the high sales of the iPhone at Verizon may put a strain on the Verizon network. So this decision is not as easy as it may seem.
To give you one more thing to think about, Apple traditionally announces new iPhones in June, so this summer there may be a better and more capable iPhone available on one or both networks. For me, the choice is easy….Just wait to see if AT&T delivers on their promises, to see if the Verizon network can handle that additional users, and to see if the next version of the iPhone is the one I can't live without.
As you might expect, people ask me a lot of questions. Because I review a myriad of cameras, printers, and cell phones, I always get questions about these devices. For the past six months, the two questions that I have been asked the most are: "Will Verizon get the iPhone?" and "When will Verizon get the iPhone?"
My answers have been: "Yes" and "Sometime this year." This week proved my answers correct. Verizon just announced that they will be selling the iPhone starting Feb. 10th with existing Verizon customers able to start pre-ordering on February 3.
Those of you who were waiting for this announcement can immediately start cheering. There is, no doubt, a pent up demand for the iPhone on a carrier other than AT&T. This is especially true in our area where AT&T service is slow and spotty. So if you are thinking about getting an iPhone from Verizon, here's what you need to know.
The Verizon iPhone uses a different underlying cellular technology. AT&T uses the GSM technology while Verizon uses a technology called CDMA. You really don't have to worry about the underlying technology except to know that the AT&T iPhone has a SIM card while the Verizon iPhone does not. Since GSM is the technology that is used world-wide, but CDMA is not, the AT&T iPhone has world-roaming capabilities but the Verizon iPhone will have extremely limited capabilities for world travelers.
Because of the differing technologies, an iPhone that was purchased from AT&T cannot be used on the Verizon network. In reverse, if you purchase a Verizon iPhone it will not be able to be used on the AT&T network in the future. In the Verizon iPhone, Apple also rearranged the antennas to improve reception. Because of this, the volume rocker switch has been moved slightly. You may not even notice the difference, but if you have an iPhone case that had a cutout for the switches, even the AT&T iPhone case may not work with the new Verizon iPhone.
However the iPhone 4, which is the current version for both AT&T and Verizon, will pretty much look and act the same. They look almost identical with Apple's slick, thin, high-tech appearance. They will both have the 940×640-pixel Retina display, 5-megapixel camera with HD video capture, and FaceTime. If you have purchased Apps from ITunes for an AT&T iPhone, all of those Apps can be used on your Verizon iPhone.
The actual price of the iPhone will be the same at AT&T and Verizon. Both are charging$199 for the 16GB iPhone and $299 for 32GB iPhone. In order to get the iPhone to work, in addition to your cellular talk and text costs, you must also purchase a monthly a data plan. This is true with all smart phones on all cellular networks. AT&T charges new customers $15 a month for 200MB; $25 for 2GB. Verizon has not made iPhone data pricing information available yet, but the company's data plans for other smart phones are: $15 a month for 150MB; $29.99 for unlimited.
One other difference between the two iPhone is that the new Verizon iPhone will be able to act as a hotspot, meaning that with an addition monthly fee to Verizon, you will be able to use your Verizon iPhone to get up to five other devices like laptop computers on the Internet. This, however, is not a big drawback for the AT&T iPhone as it is scheduled to get the same capability with a software update that will be available soon.
This brings us to another important point – iPhone updates. The iPhone has gone through 4 generations with each new generation coming with a major release of the iOS operating system, which runs the iPhone. Each of these was introduced in June. Each generation ushered in huge changes. These included things like the 3G cellular network capabilities, a compass, the ability to take video, a second camera, and a higher-resolution display.
This leaves everyone wondering if they should jump on that Verizon iPhone now or wait until this summer to see if a new version appears? The other question that is being asked is if the Verizon network is strong enough to withstand millions of new Verizon iPhone users. Although Verizon says that they are prepared for this, it obviously depends on how many iPhones Verizon sells and how much people use their voice and data network.
In any case, this is a win-win situation for consumers. Those of us who want an iPhone now have a choice of carriers and more competition between the carriers is good for the consumer.
Those of you who follow me know that I recently moved from AT&T to Verizon and from an iPhone to a Droid X. Well, now that Verizon is selling the iPad, it looks like they will also be having the iPhone soon. Wall Street Journal and others are betting that the iPhone will make its appearance on the Verizon network in the first quarter of 2011.
I made it clear that I am happier with Verizon than I was with AT&T, so several people have asked me if I would want move back to an iPhone when Verizon gets it. Unless the iPhone has some updating, the answer is no. I find the Android phone easier to use and much more customizable.
The one place that the iPhone's excels is that their dual cameras are better than any Android that I've seen. After that, Android phones compare admirably or come out on top.
For instance, the Retina display on the iPhone is fantastic. However, in a side-by-side comparison, the Super OLED screens on the Samsung Galaxy phones are almost equal. The iPhone is very thin and sleek, but it has a glass screen. Being just a tad clutzy sometimes, I would rather have a screen that is a little more drop-proof.
The Android phone's let you organize things and let multi-task more easily than the iPhone. And for me, the bottom line is that the Android lets you customize everything. With the Andoid operating system you can have 7 home pages and you can put just about anything anywhere. That allows you to create a system of organization that let's you access what you need quickly and easily.
I sure that Apple is working to improve the iPhone and in the future, it might be better than the Android phones. But for right now. Andoid is my choice!
Samsung has a new line of smart phones call the Galaxy S mobile phones. These include the Captivate from AT&T, the Epic 4G from Sprint, the Vibrant from T-Mobile, and the Fascinate from Verizon. These are phones that run the Android Operating System, have fast processors, and fantastic Super-AMOLED screens. They have a good design and sturdy built. All are candy-bar type phones with touch screens.
I took a close look at the Fascinate from Verizon and was blown away by the clarity of the 4″ screen. It was as clear and crisp as the iPhone 4's Retina display. One big difference, however, is that the iPhone 4's screen is made of glass while the Fascinate's is plastic. When dealing with a device that can be easily dropped, I'll opt for the plastic screen.
The Fascinate has a list of excellent features. The capacitive touch screen is quite responsive and is a joy to use. The battery life is adequate for a day's normal use. Call quality on the Verizon network was excellent. The Fascinate has WiFi (802.11b/g/n), Stereo Bluetooth 2.1, and an AGPS radio. It can be used as a Wi-Fi hotspot. It takes 720p videos. The camera is especially nice for a cell phone. It has auto focus and an LED back light and you have more control over the settings than I've seen in any other cell phone.
I love the Android operating system. Although this is not a deal-breaker, I would have been happier if the Fascinate came with Android 2.2, which is the current version rather than the older 2.1.
So what's else is not to like? Well, Samsung adds it's own skin over the Android operating system and I am not a big fan of this interface they call TouchWiz. It gives you Bing as the default search engine and does not allow you to change that. It has a silly on-screen puzzle-piece that you slide across the screen to unlock it. It also defaults to Verizon navigation instead of Google Navigation, which I like better. I wish that if phone manufacturers were going to add overlays like the TouchWiz, they would allow users to turn them on or off at their discretion, but right now that is not the case.
Bottom Line:
There are many good smart phones to choose from right now. The Fascinate is certainly a quite capable phone. Up against competition like the Droid X, the Droid 2, and the iPhone 4, it can hold its own. All-in-all, with the smart phone arena becoming more and more crowded, it becomes necessary to decide what is important to you and to make a purchasing decision based on that criteria. If you are looking for a cell phone with a great screen and a great camera, and you are using Verizon, this may be the phone for you.
The Good:
The Bad:
To read my more detailed review with pictures, check out Hardware Secrets.


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DIY Bun Hairstyle With Chopstick
Typically it is really easy to make yourself an elegant updo hairstyle especially with the help of a chopstick. Check out this DIY Bun Hairstyle With Chopstick hairstyle and never go back to the old typical up hairstyle. Its actually quite fun and easy to do.

subset: commoncrawl


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Americans are being subjected to more sex, violence and profane language during the traditional, early-evening "family hour" of broadcast television viewing, a U.S. watchdog group said Wednesday.
A study conducted by the non-profit Parents Television Council found that instances of violence during family-hour broadcast TV had increased by 52.4 percent since it conducted a similar study in 2001, while the amount of sexual content grew by 22.1 percent.
"In the past six years, the family hour has become even more hostile to children and families," the Parents Television Council said.
The family hour covers programs between 8 and 9 p.m. EDT Monday through Saturday and between 7 and 9 p.m. EDT on Sundays, the group said.
The Parents Television Council examined broadcast programs originally airing during three separate two-week periods of the 2006-2007 television season on the six major broadcast networks: Walt Disney's ABC, CBS, New Corp.'sFox; NBC, majority owned by General Electric; CW, a joint venture of CBS and Warner Bros.; and Fox's My Network TV. (NBC also is the parent of CNBC and CNBC.com.)


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Serves 4, prep time 10 minutes, cooking time 1 hour
4 baking potatoes
1 tbsp of olive oil
1 tbsp of rock salt
2 cups of cook peeled prawns
6 artichokes hearts chopped
1 tbsp of cayenne
3 tbsp of mayonnaise
2 tbsp of ketchup
1 cup of sliced lettuce
Preheat the oven to 180 degrees. Bring a large pan of salted water to the boil. Place the potatoes in the pan and cook for twenty minutes. Meanwhile, add the mayonnaise, ketchup and cayenne pepper to a bowl and stir, add the prawns and coat with the sauce then chill in the fridge. After twenty minutes remove the potatoes from the water and place on a lined baking tray. Prick the tops of each potato and then gently crush to break the skin. Sprinkle with rock salt and place in the oven for 45 minutes. When the potatoes are crisp and golden remove from the oven and drizzle over some olive oil. Top each potato with chopped artichokes, lettuce then top with prawns, add a sprinkle of cayenne pepper.


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Ankur worked as an MFS consultant for Asia pacific and emerged markets territory. His work was focused on telco and banks' requirements around Mobile Money, that involved designing and implementing an effective launch strategy in new markets. Ankur worked closely with the business and operations team of mobile money service providers in Asia pacific and Central American markets and brought in acumen to every plan. Prior to Panamax, he worked at different positions with Infosys, Ericsson and Mahindra Comviva, and brought 9 years of industrial experience to the table.
You can reach out to our MFS consultant for Asia pacific and emerged markets at email: email@example.com


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I have been thinking about salt and light the last couple of days. Salt is amazing and can really add flavor to a dish, it can also be very overpowering if used wrong. God calls us to be salt and light, and uses us to add flavor and illumination. When we are in sync with him and allow him to work through us he controls the amount of salt and light that are brought into our surroundings. When we go it on our own, working under our own power, we have a tendency to over season, lose our saltiness, or shine our light in the wrong direction. My prayer today is that I would be sensitive to how God is working in me and through me, and that I would never second guess the proportions he uses.
Matthew 5:13-16
Salt and Light
"You are the salt of the earth. But if the salt loses its saltiness, how can it be made salty again? It is no longer good for anything, except to be thrown out and trampled underfoot.
"You are the light of the world. A town built on a hill cannot be hidden. Neither do people light a lamp and put it under a bowl. Instead they put it on its stand, and it gives light to everyone in the house. 16 In the same way, let your light shine before others, that they may see your good deeds and glorify your Father in heaven.


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An Evening With Chip Taylor
Aug 20 , 2013 Doors: 7:30pm Show: 11:00PM
Critically acclaimed singer/songwriter, Chip Taylor is a renaissance man who is best known for hits "Wild Thing" and "Angel of the Morning." Taylor (a.k.a. James Wesley Voight) fell in love with music at the of eight when he convinced his parents to let him stay up late to listen to a country radio station. He began playing with his high school band, "Town and Country Brothers" in Yonkers, New York. After the band split up, Taylor had a brief stint as a professional golfer before suffering a wrist injury. It was then that he decided to give music his full attention. In 1961, he signed a contract with Warner Bros. Records and had his first top 100 hit single, "Here I Am." As a country songwriter, Taylor had his first big hit with Bobby Bare's version of "Just a Little Bit Later Down The Line." He continued his success in songwriting with songs that remain a staple in the American music diet, "Try (Just A Little Bit Harder)" a performance favorite of Janis Joplin, "I Can't Let Go" (The Hollies, Linda Ronstadt) and "Country Girl, City Man" (Ike and Tina Turner). Taylor has released sixteen albums thus far, and Rolling Stone acclaimed Chip Taylor's Last Chance as one of the best country albums of 1973. Since returning to music 15 years ago Taylor has been a constant presence on the Americana charts; his latest album "Block Out The Sirens" continues an amazing comeback streak. Led by special guest host journalist Steve Hochman, Taylor will discuss his decades-long career as a country songwriter and recording artist. After the discussion, Taylor will take audience questions and perform a selection of songs.
Event Schedule
- Tuesday, August 20, 2013 at 11:00pm Add to Calendar


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CRANFORD — A fifth-grade student took the Township Committee to task on Tuesday night for removing the crossing guards at two busy intersections.
Catherine McCaffrey told the committee the elimination of the crossing guards at Brookside Place and Orchard Street and Brookside Place and Gallows Hill Road makes it dangerous for students who live in that area to walk or ride their bicycles to school.
"Both are busy intersections, especially in the morning," said McCaffrey, who attended the meeting with a group of fellow students. "Many of us have waited a long time to be old enough to walk to school and now we can't."
She gave several examples of times she has tried to cross those streets, both of which have blinking lights at the intersection.
"I was with my family and we were trying to cross Gallows Hill Road, and we had to wait for 12 cars to pass before someone finally let us go," McCaffrey said. "And that's with a parent."
She also told of times she has seen other children trying to cross and were afraid to because some cars stopped for them and others didn't. She listed several streets in her neighborhood where there are children who can't walk to school due to the lack of crossing guards.
"Each time I asked my mom if the crossing guard was going to be back, and she didn't know," McCaffrey said. "So I decided to start a petition. I've been working very hard on this."
She said she went door to door in her neighborhood, talking to people about the problem. "I was very nervous to talk to the people who answered the door, but I knew it was important."
McCaffrey collected 120 signatures on her petition.
She told the committee that a police officer had come to her school to talk about bicycle safety, which just added insult to injury to the students who are unable to ride their bicycles to school because of safety concerns.
"It doesn't seem fair that some of us don't have a safe way to get to school," she said, adding that there are no alternate routes students in that neighborhood can take.
Mayor David Robinson commended McCaffrey for her willingness to tackle the issue and bring it before the committee.
"It sounds very frightening," Robinson said. "It's a public safety issue."
Commissioner Lisa Adubato told McCaffrey, "That was probably my favorite presentation ever since I've been up here."
She reassured the student that there has been money put into this year's budget to try and put back some of the crossing guards that have been removed during the past few years.
"This is an issue we have thought about a lot," Adubato said. "We can't put back everyone that was there before, and we can't tell you tonight that you can have your crossing guard back. I appreciate you bringing it back to the forefront. Please know, all of you, that you have made a difference by doing this. I give you my word that we will consider it. I can't promise it will happen but we will give it very serious consideration."
Adubato told McCaffrey that she will call the student herself and let her know what the township decides.


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In this episode we have Joe Garcia from 'Cybercrime 101', Dave Melvin and Chris Curran from 'Inside the Core', and Simon returns to join us for our Christmas Supershow Spectacular!
Today we talk about the increased risk of cyber-terrorism and the possibility of all out cyber-war, the cost of online thievery, and the current state of digital forensic education. We also talk about a complete and total Weiner.
This week we discuss the British Cybercrime Challenge, the investigation carried out inside government institutions, PI Laws, Cindy Murphy's article on mobile device investigations, and Ken Pryor's post on the SANS forensic blog.
Today we cover Paul Sanderson's blog post on forensic practitioners, how the current financial situation is affecting forensics, tips for graduates trying to get into the field, the SANS Forensic Summit, and the Forensic 4cast Awards.
The Forensic 4cast Awards, AccessData merges with CT summation, Google may face prosecution over wiretapping laws, and we talk about what to do if you child porn on your company server.
CEIC 2010, Tableau and Guidance, SANS Forensic Summit and the 4cast Awards
Here it is. The presentation I was due to give at the SANS EU Forensic Summit. Hope you find it useful. Bare in mind you'll have to have iTunes or Quicktime installed to watch this. I'll work on getting it into other formats later. Enjoy!
A brand new episode for your listening pleasure.
Rob Lee spent some time talking with me this last week. Hear the conversation here.


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(A weekly digest from the internet on chemical and biological warfare issues. Emphasis is on incidents and perspectives, but inclusion of an item does not equal endorsement or agreement with the contents. This issue covers items collected between 19 – 25 June 2017.)
CBW disarmamentBlue Grass Army Depot one of state's largest military installations (Kentucky Today, 19 June 2017): Established in 1941, this military installation, covering 14,594 acres, is the state's third largest. The facility employs over 700 people (60 percent of whom are veterans) and adds $225 million in economic value to Kentucky. Blue Grass Army Depot fulfills a number of critical missions for the U.S. Army and the Department of Defense. Contained within the Blue Grass Army Depot is the Blue Grass Chemical Activity, which ensures the safe and secure storage of the installation's chemical weapons stockpile. The chemical weapons stockpile is housed in 49 earth covered, concrete igloos on 250 acres within the larger Depot. In 1997 the United States signed and ratified the Chemical Weapons Convention, agreeing to eliminate all of its chemical weapons and former production facilities. The key mission of the Blue Grass Chemical Activity section stems from that treaty, namely, the safe storage of the chemical stockpile until demilitarization (safe destruction) is complete. U.S. Department of State Hosts Forum on Reinforcing the Global Norm Against Chemical Weapons (Office of the Spokesperson, 20 June 2017): On June 20, the U.S. Department of State hosted a high-level forum entitled, "The Chemical Weapons Convention 1997-2017: Progress, Challenges, and Reinforcing the Global Norm against Chemical Weapons." Since its entry into force 20 years ago, the Chemical Weapons Convention (CWC)—with 192 States Parties— has verified the destruction of approximately 95 percent of all declared chemical weapons stockpiles, and thereby made a significant contribution to making our world a safer place. The Organization for the Prohibition of Chemical Weapons (OPCW), the CWC's implementing body, has facilitated the destruction of chemical weapons in Albania, China, Iraq, Libya, Russia, Syria, and the United States – among others. Nonetheless, the international community's work is far from done, and serious challenges remain. Dugway Under Scrutiny Again Over Handling of Deadly Toxins (Richard Sisk, 22 June 2017): The Army's Dugway Proving Ground in Utah, which figured in a major scandal on the shipment of live anthrax, has come under scrutiny again in the handling and accounting of deadly toxins such as Sarin nerve agent. In a report last week titled "The Army Needs to Improve Controls Over Chemical Surety Materials," the office of the Defense Department's Acting Inspector General Glenn Fine found that Dugway officials failed to give immediate notice of an accounting discrepancy that showed a 1.5 milliliter shortage of Sarin.
Thousands still to go but 46,000 abandoned Japanese chemical arms destroyed in China to date


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De Gea to rescue as United escape with crucial point
S Donetsk 1 Manchester Utd 1
David de Gea spared David Moyes from the calamity of a fourth defeat as Manchester United manager with a crucial late save from Shakhtar Donetsk winger Taison in the Donbass Arena.
Moyes, without the injured Wayne Rooney, had looked on course to end his miserable run of results with Danny Welbeck's first-half opener giving United the lead against the Ukrainian champions.
But a stunning equaliser from Taison preceded a late onslaught by the home side and De Gea, dismissed as 'lazy' by former goalkeeper coach Eric Steele at the weekend, emphasised his growing importance to United by tipping Taison's 86th-minute effort over the crossbar to earn his team a point.
It was a deserved point too and a result which may, ultimately, prove to be a corner turned for United following their recent run of poor results in the Premier League.
Having gone into the game in the midst of their worst start to a season in 24 years, the loss of Rooney to a shin injury sustained in training was unfortunate.
Moyes subsequently claimed in his televised pre-match interview that Rooney would not have started the game anyway.
The original decision to name Rooney as a substitute, before his injury, suggested Moyes was focusing energies on the trip to Sunderland on Saturday, rather than this fixture.
Rooney's participation in that game would now appear to be in some doubt, which in turn would place question marks over his ability to prove his fitness in time for England's World Cup qualifiers against Montenegro and Poland.
The absence of Rooney was one of nine changes made by Moyes to the starting line-up which lost at home against West Bromwich Albion on Saturday. With Shakhtar coach Mircea Lucescu voicing his surprise on Tuesday at the extent of Moyes' rotation policy since replacing Alex Ferguson as United manager, the well-travelled Romanian could not have been surprised by the chopping and changing by his opposite number for this game.
The Shakhtar coach has seen the likes of Fernandinho, Willian and Henrikh Mkhitaryan leave the Donbass Arena in recent months, weakening a team that had become one of the more formidable outsiders in the Champions League, yet Shakhtar remain a force and they went into this game defending a 100pc record against English clubs in this competition at home.
Van Persie sent an early effort over Andriy Pyatov's crossbar from 20 yards before Tom Cleverley and Marouane Fellaini linked well to tee up Welbeck for a close-range effort.
After missing that opportunity, however, the Mancunian forward claimed his third goal of the season when he clipped the ball past Pyatov at the near post following Fellaini's pass from the byline.
The stinging criticism on the back of three defeats in four league games had clearly resonated with United's players judging by their determined performance, however.
Against West Bromwich, they were too many half-hearted challenges and half-paced runs backs into position, but it was a different story here.
Rafael was resolute at right-back, Antonio Valencia robust in front of him and the likes of Fellaini, Chris Smalling and Cleverley, all of whom have struggled at times this season, were all producing their best performances under Moyes.
The same could not be said of Patrice Evra, however, with the French full-back repeatedly troubled by the pace of Shakhtar's Brazilian winger Taison.
The home side emerged for the second half as though they had been imbued with a sense of injustice following several replays of the incident inside the dressing-room.
Shakhtar were certainly more potent than in the first half and Rafael was forced to deal with Taison's incredible pace after the winger had switched flanks with Douglas Costa.
Rafael is no slouch, but it was though he was running through treacle when he was left trailing by his fellow countryman on 52 minutes before a searing cross was delivered to the near post.
Shakhtar had three players queuing up for the cross, but De Gea was bold and reliable as he dived to smother the ball.
Lucescu's players, propelled by the noisy group of fans behind De Gea's goal, maintained the pressure on United, but Vidic was providing a one-man barrier, blocking and intercepting any ball which the home side attempting to thread into the penalty area.
Moyes may feel the time has come to ease Rio Ferdinand out of the first-team picture, but Vidic is irreplaceable and it is no wonder that plans are afoot to offer the 31-year-old a new contract.
With Moyes sensing the need to close the game up, the Scot sent on Ryan Giggs for Fellaini, enabling the Welshman to register his 145th Champions League appearance – a record in the competition as a whole, but Raul's 144 games for Real Madrid remain Uefa's benchmark due to Giggs's tally being made up with eight qualifying round outings.
Giggs's introduction could do little to stem the tide of attacks by Shakhtar, though, and the 39-year-old could only watch in vain as Rakitskiy's powerful shot bounced off Vidic and into Taison's path.
And the winger did not pass up his chance, unleashing a ferocious right-foot shot beyond De Gea and into the roof of the net.
But for the United goalkeeper's fingertip save from the save player again on 86 minutes, Moyes would have endured another defeat. (© Daily Telegraph, London)
Indo Sport


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Hypodermic needle shield
A safety retractable sheath covers an injection needle for protection against accidental pricking. The sheath extends from a base secured to the hub of the needle and has bellowed walls made of resilient material. It may be axially retracted toward the hub to expose the needle, and springs back to cover its entire length when released. A constricted section of the sheath beyond the tip of the needle is axially offset to prevent accidental exposure of the tip. A latching bellow segment surrounding the base allows for adjustment of the sheaths to the lengths of the needle.
This invention relates to medical equipment and more specifically to injection needles.BACKGROUND OF THE INVENTION
The hollow-pointed stainless steel needle in combination with syringes and infusion pumps is the common tool used in the healing arts to invade the body when giving injections or withdrawing body fluids. The sharply pointed end of a needle is extremely dangerous, and accidental pricking is very common even among nurses and other trained personnel. If accidental pricking occurs after the needle has been extracted from a patient with contaminated body fluid, the patient's disease may be transmitted to the treating physician or nurse. Procedures have been established for the recapping and safe disposal of medical needles immediately after their use. But the recapping process itself can be hazardous especially when occurring in the traumatic surroundings of a first aid treatment at the site of an accident or in the context of an emergency room intervention. Various automatic recapping systems have been devised in the past of which a typical example is disclosed in U.S. Pat. No. 4,850,996 Cree. In such case a retractable rigid tube surrounding the needle is biased by a coil spring which is collapsed when the tip of the sheath is brought into contact with the skin of the patient. The needle moves axially within the sheaths until it emerges at the distal end to penetrate the patient's tissue. This type of protective device is relatively complex and expensive to manufacture due to its multitude of components. It also does not provide a safe and automatic locking of the needle within the protective sheaths after use. Accordingly, there is a need for a simple and more effective way to automatically shield the tip of a medical needle after it has been withdrawn from the body of a patient.SUMMARY OF THE INVENTION
The principal and secondary objects of this invention are:
to provide a simple but effective retractable sheath for medical needles which can be formed as a single component;
to provide a universal protective sheath that can be adapted to a variety of types and sizes of needles;
to provide some protection against the accidental retracting of the sheaths after the needle has been withdrawn from a patient's body; and
to provide sheaths which constitute a minimum interference with the use of the needle under a variety of circumstances.
These and other objects are achieved by a collapsible sheath which extends from a base attachable to the hub of a needle to cover the pointed tip of the needle. The sheath is made of a succession of bellowed sections which collapse to a very short length near the hub of the needle. The distal aperture through which the needle emerges is axially offset from the axis of the needle and sheath, so that when the sheath is expanded after use, the misalignment between the aperture and the needle tip prevents the accidental reappearance of the latter.BRIEF DESCRIPTION OF THE DRAWING
FIG. 1 illustrates a syringe and needle assembly equipped with the invention in the process of an injection;
FIG. 2 is an elevational view of a first embodiment of the invention with a partial cut-out showing the internal structure;
FIG. 3 is a cross-sectional view taken along line 3--3 of FIG. 2;
FIG. 4 is a proximal end view of the sheaths;
FIG. 5 is a partial cross-sectional view of a second embodiment of the sheath's proximal section; and
FIG. 6 is a cross-sectional view of the distal ends thereof.DESCRIPTION OF THE PREFERRED EMBODIMENT OF THE INVENTION
Referring now to the drawing, there is shown in FIG. 1 a syringe and needle assembly 1 wherein an hypodermic needle 2 which is shown penetrating the epiderm 3 of a patient is equipped with a retractable sheath 4 illustrated in an almost complete retracted position. The sheath comprises a frusto-conical base 5 which is internally dimensioned to intimately engage the hub 6 of the needle 2. The hub itself is connected to the outlet tip of the syringe 7. A collapsible sleeve 8 extends coaxially from the distal end 9 of the base around the cannula 10 of the needle and terminates in a constricted distal section 11 which has a much lesser cross diameter than the bulk of the collapsible sleeve 8. The entire sheath is formed from a resilient material in its expanded position so that after being compressed as shown in FIG. 1 as the needle penetrates the patient's body, it will automatically spring back and cover the entire needle as it is withdrawn from the body.
The construction of this first embodiment of the sheath 4 is better illustrated in FIGS. 2-4.
The sheath 4 has a length commensurate with the length of the cannula 10 of the needle, except for the terminal tip section 11 which extends beyond the pointed end 12 of the cannula. The base 5 is substantially frusto-conical with a coaxial opening 13 in the proximal end which is commensurate with the diameter of the proximal half section 14 of the needle hub 6. Since the hubs of a large majority of medical needles are substantially conical, a universally sized base 5 can adaptably engage over the hubs of a wide range of medical needles of various sizes. Four semi-circular tunnels 14 on the periphery of the base 5 extend almost the entire length of the base, tapering down slightly toward its distal end 9. The tunnels 14 serve two purposes. First, they facilitate expansion of the diameter of the base 5 when it is forceably engaged over the conical hub 6. Secondly, the inner channels 15 defined by the tunnels provide an escape for the air when the sheath is retracted. The bellowed main body of the sheath 4 is formed by alternately inverted frusto-conical sections 16 and 17 which are joined along inner folding ring sections 18 and outer folding ring sections 19. The inner and outer folding ring sections 18, 19 are formed integrally with the frusto-conical section 16, 17 during the molding process, and in the extended bellows position illustrated in FIG. 2. The entire sheath is made from a preferably transparent resilient material. Accordingly, if the sleeve 8 is retracted or collapsed toward the base 5 it will bounce back to its extended relaxed or resting position illustrated in FIG. 2. The material may be selected from a group of resins such as polyethylene terepehalate suitable for medical applications.
In this first embodiment, the successive alternately inverted frusto-conical sections 16, 17 and the walls are at a substantially same angle with the axis XX which is common to the sheath 4 and to the needle 2. This angle may be from 30 to 80 degrees. However, a slight widening of the bellows of one or two degrees away from the base 5 tends to favorize a more compact stacking of the compressed bellows as shown in FIG. 1, as the most distal ones extend over the proximally adjacent sections. The compacting effect may be improved by making their inverted frusto-conical sections 17 slightly shorter than the adjacent frusto-conical sections 16.
The top section 11 forms a generally elongated frusto-cone about an axis YY which is parallel but slightly offset from the axis XX of the sheath and needle. About three-quarters of the periphery of the tip 11 is indented with a series of crescent-shaped wedges 20 of progressively diminishing radius. The top and bottom converging walls 21, 22 of each indentation are positioned in axially alignment with the cannula 10 when the sheath is in its relaxed position. If the sheath is axially retracted, the pointed tip 12 of the needle would have to perforate up to ten layers of material, that is, go through all the crescent-shaped converging walls 21, 22 before exiting beyond the tip section 11. However, the cannula 10 will emerge beyond the distal end 23 of the tip section 11 if that section is slightly tilted or shifted to engage the pointed end 12 into the channel 24 constituted by the non-indented portion of the tip section 11. This can be accomplished by first contacting the area of the patient's skin which must be penetrated by the needle at the slight oblique angle with the distal end 23 and maneuvering the needle tip 12 through the channel 24 as the needle is being thrust axially forward. This maneuver is greatly facilitated by the transparency of the sheath. Alternately, the median section of the sheath can be manually withdrawn or retracted until the pointed end 12 of the needle is engaged into the channel 24 before thrusting the needle through the patient's epiderm.
A second embodiment of the invention is illustrated in FIGS. 5 and 6. The differences with the just-described first embodiment resides in the treatment of the base and most proximal bellows sections. In this second embodiment, the base 25 is substantially similar to the base 5 of the previous embodiment except that the bellows sections are not attached to the distal end 26 but to the periphery of the proximal end 27. The frusto-conical sections 28 of the bellows which surround the base 25 have inner ring sections with a diameter approximately corresponding to the outer diameter of the median area 29 of the base 25. Furthermore, the inverted frusto-conical sections 30 are slightly shorter than the non-inverted adjacent sections 31. The outer ring sections 33 are beaded and axially grooved to allow folding at a very acute angle without breaking of the material. Only a limited number of bellows sections are so configured. The remainder and bulk of the bellows sections 33 are similar in construction as the bellows sections of the first embodiment. As the most proximal bellows sections are tightly folded in an overlapping configuration 34, the inner folding rings 35, as they move axially around the base 25 come in contact with the outer wall 36 of the base and become jammed against it effectively locking the proximal bellows sections into the collapsed configuration 34. The overall length of the sheath 4 can thus be adjusted until the pointed end 12 of the needle is engaged into the channel 24 of the tip section 11 which is constructed and offset as in the previous described embodiment. Once caught in this position, the needle and sheath are ready for thrusting into the patient's body without further manipulation. Once the needle is withdrawn from the patient's body, the sheath will automatically expand under its own resiliency with enough inertia to unlock at least one proximal bellows section so that the pointed end 12 of the needle will be completely covered and safely shielded behind the indented tip section 11. In the event that the pointed end 12 of the needle remains engaged into the tip section 11 as shown in FIG. 6, a pinching pressure applied to any part of the bellows section will radially collapse it at least one of such sections, thus further expanding the sheath to dislodge the pointed end 12 of the needle from the channel 24 and prevent accidental retraction of the sheath.
While the preferred embodiments of the invention have been described, modifications can be made and other embodiments may be devised without departing from the spirit of the invention and the scope of the appended claims.
1. In combination with an injecting needle having a rigid cannula extending from a coaxial hub for connecting to the outlet of a syringe or the like to a pointed distal tip, a retractable sheath which comprises:
- a hollow base shaped and dimensioned to intimately engage over the hub;
- a sleeve extending coaxially from the base around the length of the cannula, said sleeve being formed by a plurality of alternately inverted frusto-conical segments joined by resiliently pliable alternating inner and outer ring sections;
- wherein said alternately inverted frusto-conical segments and ring sections are integrally molded from a common resilient material; and
- wherein said sleeve comprises an end portion having a substantially lesser cross-sectional diameter than the major part of the sleeve.
2. The combination of claim 1, wherein said end portion extends beyond the distal tip of the cannula when the sleeve is in said resting position.
3. The combination of claim 2, wherein said end portion lies about an axis substantially parallel and spaced apart from the axis of the needle and sleeve.
4. The combination of claim 3, wherein a succession of contiguous frusto-conical segments have alternating long and short heights.
5. The combination of claim 1, wherein said sleeve extends coaxially from the proximal end of and around said base.
6. The combination of claim 5, wherein said succession of contiguous segments surround said base.
7. The combination of claim 5, wherein the outer ring sections joining said succession of contiguous segments are beaded and internally grooved to facilitate folding.
8. In combination with an injecting needle having a rigid cannula extending from a coaxial hub for connecting to the outlet of a syringe or the like to a pointed distal tip, a retractable sheath which comprises:
- a hollow base shaped and dimensioned to intimately engage over the hub;
- a collapsible sleeve resiliently biased to extend coaxially from the base around the length of the cannula in a rest position;
- said sleeve comprising a distal end portion having a substantially lesser cross-sectional diameter than the major part of the sleeve, and extending beyond the distal tip of the cannula when the sleeve is in said rest position; and
- wherein said end portion lies about an axis substantially parallel and spaced apart from the axis of the needle and sleeve.
9. In combination with an injecting needle having a rigid cannula extending from a coaxial hub for connecting to the outlet of a syringe or the like to a pointed distal tip, a retractable sheath which comprises:
- a hollow base shaped and dimensioned to intimately engage over the hub;
- a collapsible sleeve extending coaxially from the base around the length of the cannula, said sleeve comprising a distal end portion having a substantially lesser cross-sectional diameter than the major part of the sleeve, and extending beyond the distal tip of the cannula;
- said end portion lying about an axis substantially parallel and spaced apart from the axis of the needle and sleeve; and
- wherein said end portion comprises a plurality of indentations projecting across the axis of the needle and sleeve.
Type: Grant
Filed: May 1, 1990
Date of Patent: May 14, 1991
Assignee: Ian Campbell Cree (Shelburne)
Inventors: Zoltan Soproni (San Diego, CA), Joseph A. Charmasson (San Diego, CA)
Primary Examiner: John D. Yasko
Attorney: Henri J. A. Charmasson
Application Number: 7/517,326
International Classification: A61M 532;


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Wouldn't it be awesome if we all went through life on an even keel, no matter what happened it didn't phase us?
Equally wouldn't it be awesome if Winston Churchill was right and success was actually going from failure to failure without losing enthusiasm?
If we did have that even keel would we have as much fun? would the lack drama in our lives keep us as engaged and interested enough to do it all again tomorrow?
Fact is we all have moods, life has ebbs and flows, shit happens both good and bad. Failure while a fantastic learning opportunity does effect us a very personal level and impacts our ability to cope or have the resilience to pick ourselves up and do it again – it seems so we can fail again and learn some more. Drama is what keeps it interesting. As a business owner the high highs and the low lows do happen and they do drive us to come back tomorrow to achieve the high again or to avoid ever experiencing another of those lows.
Understanding The Struggle
My all time go-to blog when feeling what I now understand to be The Struggle is Ben Horowitz post titled "The Struggle". Discovering this blog revolutionised my life – not in that it provided answers, it doesn't, it provides context and a shared experience. Everything he lists in defining The Struggle had me nodding and agreeing, his post told me I am not alone and that really mattered to me.
Read this blog! tell me if you don't have that same ah-ha moment and if it doesn't change your life, even a little. Here is a tiny taster to get you interested in reading The Struggle:
- The Struggle is when you wonder why you started the company in the first place.
- The Struggle is when you are surrounded by people and you are all alone. The Struggle has no mercy.
- Every great entrepreneur from Steve Jobs to Mark Zuckerberg went through The Struggle and struggle they did, so you are not alone. But that does not mean that you will make it. You may not make it. That is why it is The Struggle.
His summation at the end of the section "some stuff that may or may not help" helped me the most:
Remember that this is what separates the women from the girls. If you want to be great, this is the challenge. If you don't want to be great, then you never should have started a company.
Is there an art to coping?
Having felt a little tired and a little stressed recently I reread The Struggle to validate that I am not alone in the world then half heartedly reached to the internet to read about good coping mechanisms, thinking I would only find articles on sleeping, eating well, exercising and all the things I know I forgo when stressed. Alongside those usual tips there were a couple of good sources of advice with specific techniques that I knew all along, and I even tell other people to do, but found myself forgetting:
- reframe negative thoughts
- maintain focus on what matters
- talk it out
For me talking is the best technique, I verbalise to think things through (often mistaken for verbal diarrhoea) so for me it's logical to talk it out. Recognising my stress symptoms as a prompt to go talk through the cause is, it seems, my biggest challenge.
So this got me thinking – what if you don't have a natural support network who provide that sounding board function? or what if the stress is being caused by your usual support network not being their usual sounding board? here are a few ideas:
- find a mentor, this can be hard – to find a person who understands your context, has walked in your shoes and is willing to give you their time as your mentor – hard but possible, people are generous and supportive of others experiencing the startup or growing pains they have overcome themselves
- find a business partner, if you do not have a co-founder or partner to work through the challenges with it can be hard to find one who will share your vision, passion and moral basis – again hard but possible, business partners can join your business at any age or stage with the right motivation and agreements in place
- share with your team, Antony Horowitz does provide this insight within his post. He suggests you won't be able to share every burden but share every burden that you can.
If talking isn't your coping mechanism identifying the technique that talking provides for me should be top of your list. Finding effective means of reframing your thoughts, pushing through the current struggle and coming out the other end in as shortest timeframe as possible (I don't like to take my struggle into the next day, it would waste a perfectly productive day) will make a difference.
Remember every business owner faces the struggle, key is to find ways you are not facing it alone. Happy sharing, Vic.
Some of the useful links referred to in this blog post:


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We engage you… Entertainment, Encouragement, Inspiration, Education and Shenanigans. All on one blog!
Lifetime has added another R&B biopic to their future schedule. Lifetime revealed Monday that Disney darling Zendaya Coleman has been tapped to portray Aaliyah, the beloved '90s singer who lost her life in a plane crash. Source
What do you think of Zendaya playing Aaliyah? Zendaya is a beautiful and talented girl, but I just can't see her as Aaliyah. Hopefully she can pull it off. Disney actors tend to be excellent at what they do. But I have to admit, my personal pick would be Ciara or Keke Palmer. Who would you pick?


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Sunni Political Islam: Engine of 'Israeli-Palestinian' Conflict
An oft-repeated sentiment currently doing the rounds in discussions of the Israeli-Palestinian issue is that it is imperative that the conflict not become a "religious" one. This sentiment, guaranteed to set heads nodding in polite, liberal company, stands out even within the very crowded and competitive field of ridiculous expressions of historical ignorance found in discussion of the Israeli-Palestinian issue.
This sentiment is connected to the recent wave of terror attacks in Jerusalem, which are the result of Palestinian claims that Israel is seeking to alter the "status quo" at the Temple Mount. As this theory goes, up until now this conflict had mainly been about competing claims of land ownership and sovereignty, but it is now in danger of becoming about "religion," and hence turning even more intractable. So this must be prevented.
In objective reality, the conflict between Jews and Arab Muslims over the land area between the Jordan River and the Mediterranean Sea has been, from its very outset, inseparable from "religion."
On the Arab/Palestinian/Muslim side, recent events in the Levant (specifically in Syria and Iraq) ought to have taught us just how very flimsy and contingent the supposed "secular, national" identities of the local populations are. Both these identities have now largely been eclipsed, replaced by sectarian, ethnic, and religious markers of loyalty. As Professor Mordechai Kedar pointed out in a recent article, there is no reason to think that a "Palestinian" national identity is any stronger or more durable than either of these neighboring constructs.
This does not mean, of course, that the Arabic-speaking population of the area is not mobilized for struggle. The events of recent days suggest a murderous commitment to the fight. The engine for this commitment, however, is a religious one.
The engine is the determination to prevent the Jews from in any way, be it ever so minor, infringing on the situation of de facto Arab Muslim domination of the Temple Mount/ Haram al-Sharif area. This commitment is not a new development; it has in fact been the driving force of the conflict throughout.
The very first major instances of Arab Muslim violence against Jews in the 20th century were related to this self-same area. In 1929, it was precisely an attempt by Jews to assert Jewish prayer rights at the Western Wall that led to a furious Arab and Muslim counter-reaction. This reaction led to the slaughter of over one hundred Jews and the destruction of an ancient Jewish community (in Hebron).
The supposed threat to the mosques at the Haram al-Sharif and the alleged desire of the Jews to build the Third Temple continued to form a staple in Arab propaganda against the Zionists in the 1930s and 1940s. This was a time when the nascent Palestinian "national" movement was led by a man holding a position of religious authority: Jerusalem Mufti Haj Amin al-Husseini.
This centrality of religion continued to fire the various movements fighting Israel. The very name "Fatah," for example, which is often – absurdly -- described as a "secular" movement, is a religious term. "Fatah" is in Arabic a term literally meaning to "open," but is used in context to mean "to conquer a land for Islam."
The central role of religion in this conflict has served to prevent the eventual resignation to and compromise with Israel's presence, which many early Zionist leaders predicted. This prediction was based on similar national conflicts elsewhere, where after a period of struggle the two sides grow tired and settled their difference, cutting a deal.
But religious sentiments have a way of not growing tired.


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Visiting Miller Systems is best done by walking and public transportation. But if you are driving to our offices, there are several parking options available in the immediate vicinity. Keep in mind that events at the TD Garden (view calendar) make parking more difficult and, often, more expensive – plan ahead.
There are often metered spots available within a short walking distance of the Miller Systems HQ. depending on which street you're on, you may find traditional parking meters or newer multi-space meters – both provide a maximum 2 hours or parking.
31 Lancaster Street
208 Friend Street
121 Nashua St
92 Sudbury St.
50 New Sudbury Street


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(October, Halloween, 2014)
I first met Freya in a night-club on Halloween. I was made-up as a zombie suffragette, and I stumbled in to her and her friends at the bar. They kindly complimented my ensemble and told me I should've won the prize for best costume. Unfortunately, that crown had already been bestowed on the head of a man dressed as a giant sanitary towel. To this day, that irony hurts more than the worst menstrual cramp.
Freya & I got chatting. She told me she'd never been to the area clubbing before, but she was having a good time, even though she was designated driver. I probably mumbled some drunken nonsense about a) people stealing my hat, and b) how I loved the walls of the watering hole we were both in. We went our separate ways after taking each other's Facebook names, and I woke up the next day looking like death (I still had all my zombie make-up on, which frightened the life out of my friend in daylight).
After I'd recovered from the vodka-based anarchy of the previous evening, I went online to find that Freya had messaged me. She asked the usual 'How are you? How's the hangover?' before revealing the unusual: 'I don't know if you noticed, but I'm transgender. I just like to let people know, to be sure they're ok with it'.
I'd be lying if I said I wasn't surprised by Freya's message, but I genuinely hadn't realised she was a transgender girl when I met her. I thought she was just a girl in a club on Halloween, wearing devil horns. She felt comfortable enough to tell me details about her transition, and all I could think was 'good for her'. It's hard enough trying to be yourself in a county/country that is obsessed with the way women look, let alone trying to be yourself when you feel you're trapped in the wrong gender.
Up until this point, I had never met anyone, male or female, who identified as being transgender, but I knew it wasn't something which bothered me in the slightest. 'Live and let live' – as my Mum reminds me – and that was my thought process when Freya bravely told me about her situation.
Later in the evening, she uploaded a vlog about her night out. I watched it, and I was humbled beyond words when she mentioned how meeting me had brought up a lot of conflicted, but good feelings for her. You can watch the video below (she's quite the Youtube star these days!)
Since October 2014, we have kept in touch through emails and messages with the intention of meeting up in person to talk over coffee. Unfortunately, due to studying/work schedules/location/other issues, this hasn't been a possibility (but it's still in the pipeline and that's what counts!)
Through messages and watching her vlogs, I learned that Freya also suffers with Bipolar Disorder and is on the autistic spectrum. I sympathise immensely with her struggles, and celebrate her victories whenever she shares them with me. This is why I was so flattered when she asked to record my blog entries as part of a new podcast series for her Youtube channel. She said reading my entries aloud helped her to practice feminising her voice, as well as introducing her followers to a female/feminist perspective on art, culture, and life in general (I'm definitely not the best critic on any of these subjects, but it's kind of her to consider me in this light).
Freya's offer was too good to refuse, and she's already recorded several of my blog entries. They're released every day, 8:00am, on her Youtube channel (click here to watch & subscribe). I'm grateful that she took the time to read, record, and enjoy them. I look forward to more of her vlogs, and that cup of coffee we still need to drink! Listen to our first podcast below:


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A new episode of EJIL: Live!, the Journal's official podcast, is now available. Episode 2 of EJIL: Live! features an extended "Fireside Chat" between the Editor-in-Chief of the Journal, Professor Joseph Weiler, and Oliver Diggelmann (University of Zurich) and Tilmann Altwicker (University of Basel), whose article "How is Progress Constructed in International Legal Scholarship?", appears in Vol. 25, Issue 2 of EJIL. The interview was recorded at the European University Institute in Florence, Italy. Video and audio available here.
Comments Off on EJIL: Live! – Episode 2


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A range of barline symbols for most ordinary purposes can be found in the Barlines palette (Basic workspace); repeat barlines, only, are also available in the Repeats & Jumps palette (Basic and Advanced). Additional symbols can be found in the Barlines palette of the Advanced workspace. It is also possible to create your own custom barlines (see below).
Change barline type
To change an existing barline, use one of the following:
- Select a barline, or measure, then double click an icon in the Barlines palette.
- Drag an icon from the Barlines palette onto a barline, or a measure, in the score.
- Select an existing barline, then adjust "Style" in the "Barline" section of the Inspector.
To change a non-single to a single barline:
- Select the barline and press Del.
To hide a barline:
- Select the line and press V, or uncheck Visible in the Inspector.
Insert barline
To insert a new barline between existing ones, either:
- Drag an icon from the Barlines palette onto a note or rest.
- Select a note or rest, then double-click an icon in the Barlines palette.
Split a measure
You can insert a barline in order split a measure. Use one of the following methods:
- Press Ctrl (Mac Cmd) and drag the line to the first note of the new measure.
- Select the first note of the new measure and press Ctrl (Mac Cmd) while you double click a barline.
Note: As of version 3.1 (or earlier), all barlines entered this way are entered as Normal Barlines. See also Split a measure.
Custom barlines
It is possible to create custom barlines by selecting one or more barlines, and adjusting the properties in the "Barlines" section of the Inspector:
- Style: Choose from a range of preset barlines.
- Span to next staff: joins the selected barline to the barline in the staff below.
- Span from: Sets the position of the top of the barline. "0" is the top staff line. Positive numbers start lower down the staff, negative numbers above.
- Span to: Sets the position of the bottom of the barline (see "Span from").
- Span presets: Use the buttons to apply preset customized barlines.
See also Mensurstrich.
Changes to color and horizontal/vertical offset can also be made in the Inspector.
Connect barlines
Barlines may extend over multiple staves, as in the grand staff of a piano, or in an orchestral score to join instruments in the same section. To join barlines:
Double-click on a barline to enter Edit mode.
Click on the lower blue handle and drag it down to the staff you wish to connect to. The handle snaps into position so there is no need to position it exactly.
Press Esc to exit edit mode. This will update all other relevant barlines as well.
See also
- Measure operations
- Repeats and jumps for information on repeat barlines
- Add fermata to barline


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Dawn Kregel has filed a lawsuit in the Eastern District of Texas, Sherman Division, against the makers of the NuvaRing birth control device alleging the contraceptive caused her to suffer Deep Vein Thrombosis (DVT) shortly after she began using it.
The lawsuit names Merck & Co., Schering-Plough Corp., Organon USA Inc., Organon Pharmaceuticals USA Inc., and Organon International Inc. as defendants, and accuses that the companies failed to warn that NuvaRing has been associated with more thrombotic events than other birth control medications.
The lawsuit also alleges that NuvaRing makers made, promoted, and advertised that NuvaRing had a relatively low amount of estrogen to hide the fact that it has a high level of dangerous third-generation progestin, the Southeast Texas Record reported. Kregel said in the complaint that had she known about the increased risks associated with NuvaRing, she would have used a different birth control method.
Kregel had used NuvaRing for just over a month when she developed DVT.
The lawsuit alleges strict product liability, negligence, breach of warranty, fraud, misrepresentation, and consumer fraud. The lawsuit seeks a jury trial and over $10 million in damages for medical expenses, loss of time from employment, loss of quality of life, pain, exemplary damages, attorneys fees, and court related costs and fees.


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The best way to reach any department within Pick-A-Slip is through E-Mail. While we understand it can be inconvenient to some we assure you that our customer service has and will continue to be our first priority. All inquries are responded to via E-Mail within 24 business hours.
Office hours:
Monday - Friday 8:00am - 5:00pm
Saturday - Sunday Closed (Feel free to Email us and we will respond Monday morning)
Customer Service:
Technical Support:
Marketing Department:


text: Dental veneers can instantly transform your smile by masking chips, gaps, stains, and misshapen teeth. When you visit our office, our dentist and team can provide you with high-quality, custom-made dental veneers. We invite you to contact Dr. Evan Wheeler's office today if you are interested in receiving dental veneers in Fairbanks, Alaska.


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French Country Living Room Decorating Tips
Making a French country living room can be accomplished through the use of French country style decor. Here are some tips to create a French country living room. Paint the walls in your living room a subdued, extremely light shade of yellow. Yellow walls radiate French country and allow you to place color elsewhere in the room. Commonly, French Country living rooms have two primary colors: yellow, and blue or red. Yellow is the main color of the room, typically found on the walls as well as on some furniture and drapes. Blue or red is used as an accent color in a French country living room. Place blue or red accent items throughout the room, but limit the amount of them, too many blue or red items will take away from the French country look and feel of the room. Utilize an old birdcage as a decorative item in your French country living room. Place the birdcage on your fireplace mantel or on an end table. Placing the birdcage on the fireplace mantel highlights the birdcage and immediately creates a country look and feel in the room.
Select a variety of white and blue or red plates of different sizes for display in your French country living room. The differing sizes lend more visual interest to the display. If you have china plates in storage or sitting in a cabinet, utilize them in the living room. Purchase plate hangers and hang the plates on a wall. Group the plates together to create a focal point. Place your furniture so that the pieces face each other with a coffee table in the middle–for example, two love seats placed in the middle of the room facing each other, divided by a coffee table.
French Country Living Room With Yellow Walls
When choosing furniture for a country living room, you may want to browse places other than furniture stores for unique pieces.
French Country Living Room With
Choosing the paint colors as well as floor coverings is an important aspect of making a country living room.
French Country Living Room With Long Curtains
A country living room allows a lot more freedom than other living room designs, because a country design by definition looks good with an eclectic mixture of furniture and decorations.
French Country Living Room With Ornate Mirror
The French Country look combines elegance, nature and country into one decorative style.
French Country Living Room With Leather Sofa
It's time to turn your living room into one that radiates the look and feel of a cottage in the country.
French Country Living Room With Fireplace
French Country Living Room With Round Ottoman
You don't need to live in a farmhouse, saltbox or log cabin to create french country-style rooms.
French Country Living Room With Floral Sofa
Country is a classic decorating style. A country-style living room is warm and welcoming.Label: country living room pictures, country living room pics, country living room ideas, french country living room, country living room style, .


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Beating Spurs a positive in a wild Nuggets season
So what's the value in Friday's 102-98 win over San Antonio?
The Nuggets say there was huge value. No matter who was on the court for the Spurs.
"We are the only team in the NBA to beat Golden State and San Antonio (in the same season), which is kind of amazing," Nuggets coach Michael Malone said. "I don't care if they rested most of their starters, we still beat them."
A bit later in the press conference… "I give our guys credit; they did a great job of getting on track tonight. The last three games we got away from who we are and to play this way against San Antonio couldn't have come at a better time." Read more…


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It's time for your Whole30 Week 3 Check-In!
Now that you've got some experience under your belt, it's time to chat about what the upcoming week is likely to bring. (Of course, you truly are a unique snowflake, so individual experiences may vary.)
By this point, you should over everyone's favorite, the Carb Flu, and on to some of the more pleasant effects of this nutritional reset: more energy, better sleep, a better relationship with food and perhaps even some changes in body composition. It's been my experience that the beginning of Week 3 tends to come in gently and, in some cases, ends on a much unexpected note.
You see, it's not unheard of for folks to fall off the rails, particularly at the end of Week 3. And for some reason, Day 18 seems to be a really common number. What the heck is going on? Why would you make it past the halfway point and then give in?
For some reason, they tend to start acting up during this week, remnants of bad habits past which try to convince you that you'd be so much better off with just a smidge of that cake or just one glass of wine. The solution? Tell your brain to shut up. Seriously. Whole9 often says if you're not hungry enough to eat steamed fish and broccoli, you aren't really hungry…you're experiencing a craving. Most cravings pass within just a few minutes, so find a way to distract yourself until it passes.
And then, there's sabotage via boredom.
My own theory on why this happens goes sort of like this:
Week 1: "Look at this huge challenge ahead of me! It's game on, self!" Everything is new, and you're on the lookout for any food saboteurs, ready to squash them in a moment.
Week 2: "Heck yeah! I'm finally feeling better. This is AWESOME." You start to enjoy the benefits of kicking crappy food and eating habits to the curb. You're thinking, "I'm going to ride this wave to Day 30."
Week 3: "Scrambled eggs for breakfast and grilled chicken for lunch? Again?" If you're not careful, your wave riding can turn into a wipe out. Boredom and complacency, in combination with cravings, can ruin your clean streak if you're caught unaware.
There's also a tendency to think, "I feel better so I can just stop and keep feeling good even if I go back to old ways." In many cases, you may not start to feel all the positive effects until you're IN Week 3 so don't give up. Why? If your gut really needs some intense healing, it may take longer.
What to do?
Don't get caught by boredom. Mix it up and make some new recipes (suggestions for that below). Buy some new ingredients that you've never used or try going out to eat. (I suggest you check out the menu at home and have a plan for making some modifications to your order.) With a little awareness, you can sail smoothly into Week 4.
Here are some awesome resources in case you need some inspiration:
- The brand new Whole30 website
- Whole30 2014 Week 1 Meal Plan from The Clothes Make the Girl
- Whole30 2014 Week 2 Meal Plan from The Clothes Make the Girl
- Whole30 2014 Week 3 Meal Plan from The Clothes Make the Girl
- 30 Whole30 Breakfasts from Meatified
- 30 Whole30 Lunches from Meatified
- 30 Whole30 Dinners from Meatified
- 5 Ways You're Sabotaging Your Whole30 from Meatified
- It Starts with Food from Whole9
And, for even MORE goodness, click on the images below to print or download these super-duper helpful guides from Whole30!
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Melissa and Darija grilling burgers
Our beautiful flowers are always a topic for conversation
Sioux Falls, SD, Retirement Communities
On Wednesday July 8th the Sioux Falls Primrose had a Summertime BBQ for friends and residents. It was attended by 150 people and was a great way to spend the evening. On the menu was grilled burgers, hotdogs, chips, baked beans, watermelon, and ice cream bars. Everyone had a great time enjoying the wonderful food and the socializing, and some of our residents and their friends also played bean bags out on the lawn. The social atmosphere was a lot like being together for a 4th of July holiday celebration, and we even had some folks dressed in red, white & blue. Ursie Wittrock, one of our residents, commented on the great food and would like to have it again!
Summer is in full force and having a picnic style event is one way of showing our appreciation to our residents. We are a lot like a family here in Sioux Falls, and it is fun to put a smile on our residents' faces!
To find out more about the retirement living experience at Primrose, please contact your nearest Primrose Retirement Community today to see more of our fun and social living. We'll happily answer all your questions and show you around our beautiful communities. Come see why we say, THIS IS LIVING!


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Why Your Content Marketing on Social Media isn't working!
Content on Social Media is meant to be shared. That is how content marketing works on this platform. It gives your brand more exposure – to different kinds of people – and increases your "value" in their eyes.
But there are times when content – regardless of however good it is – does not get shared!
Why is that?
Here are some reasons –
No Images –
Visuals are very important when it comes to content – be it video or an image. People tend to see and therefore share visual content. So if your article or blog is just large chunks of text, chances are, people are going to give it a miss.
No grabbing headline –
If your headline is not compelling enough, readers would just gloss over your post and go to the next one! Interesting and attention-grabbing headlines make people want to click to read more. Experts tell us to include some action-based word in it! Also don't make it too long! It needs to be concise and entice the reader into wanting to know more!
No correct length
If it is too short, it would appear that there is not enough meat / enough depth to your article. If it is too long, it wouldn't work either. The best length is between 1000 and 1500 words. But regardless of the word count, what matters is the quality of the content that you put up. That will definitely get shared!
No focused target audience
You can never be everything to everyone. You can't just target everyone! You first need to know who you are addressing the content to. And then when you tailor your message to suit the audience, your content gets more appealing to that group. The key, is to get to know your audience so you can produce stuff that addresses their needs
No appeal
And then there is the most obvious reason – that the content that is put out there is not appealing. Your audience did not like it. And they did not think that their circle would be interested in that as well. So it just doesn't get shared. Again – the way to better this is to know your audience well enough to know what they would be interested in.
No visibility
You might have written the best content ever – but it needs to be in a place of visibility to your target group. The problem with most blogs is that no one even know that they exist! So unless this is rectified, this kind of content will remain hidden from the world! Don't just stop with writing a great blog – promote it.
No share options
If you have posted a blog, please make sure you include some sharing buttons in it. This makes sharing easy and takes away the pain of copying the link and sharing it with others. If you want people to share your content, make sure that you make it easy for them to do so. So make sure there are share buttons – and those buttons are easy to spot and easy to use on your page!
There are many facets to this whole thing – you need to first generate content that is great and which people would find useful and interesting. Content that begs to be shared. You need to engage with your customers establishing yourself as someone who is an expert and a thought-leader in your field of expertise. You need to connect with your audience and your customers and build relationships with them. And you need to make your content easy to share.
It is as easy as that!:


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Device Overview
The Mini-MT GPS tracker from Enfora is robust personal tracker device with a wide range of functionality and field deployment. Enfora has equipped the Mini-MT with a several customizable input keys. A programmable panic button generates a custom alert that can be customized with several different properties from the GeoTrack GPS tracking platform. Also, the Mini-MT is capable of making 2-way voice calls over GSM with the speaker & mic. A user programmable phone number can be added for emergency phone calls. Request information


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Signs & Symptoms of Perfume Allergies
People generally wear perfume and use scented toiletries to impart a clean, fresh, sometimes sexy scent as they pass through a room. If you have perfume allergies, the lingering fragrance in the air or on your skin can cause a plethora of unpleasant symptoms. Consult your doctor if you show signs or symptoms of perfume allergies or fragrance sensitivities.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Contact Dermatitis
Contact dermatitis is a sign that your skin is irritated from a particular substance. Perfumes, as well as scented soaps, body care products and laundry detergent, can cause an adverse skin reaction in response to an allergy. The skin becomes red, itchy, painful, sometimes swollen and dry at the site of contact with the allergen. Topical corticosteroid creams such as hydrocortisone help reduce the inflammation. Speak to your doctor before treating allergic contact dermatitis at home to ensure your safety. Eliminate all contact with the perfume to avoid future reactions.
Respiratory Symptoms
Perfume allergies can affect your respiratory system even when you are not wearing the perfume yourself. The scent of a product on somebody else can trigger your immune system to release histamines if you have a fragrance sensitivity or allergy. Symptoms include a runny nose, sneezing, watery, itchy eyes and headache. Signs of perfume allergy can also include breathing difficulties such as wheezing. Taking an oral antihistamine, under the supervision of your doctor, may provide relief.
Allergy Testing
Allergy testing is a diagnostic tool that tells you if you have an allergy, intolerance or sensitivity to perfume or other fragrances and chemicals. Allergy testing is also used to determine allergies to food and pet dander. Perfume allergies are discovered through reactions to patch testing. An allergen, such as a perfume, scented lotion or other cosmetic, is placed on a patch which is applied to your skin. You most likely have an allergy to the perfume or chemical if you show signs of irritation in the target areas. Patch testing is carried out over a period of two days. If you show no reaction to the perfume within 48 hours, you probably don't have a true allergy.
As much as 30 percent of the American population finds perfume and other cosmetic scents physically irritating, according to studies published in the March 2009 issue of the "Journal of Environmental Health." This relatively high number of people who have possible allergic reactions to perfume is also likely to exhibit asthma symptoms and signs of other chemical sensitivities 3. Perfume allergies, depending on the extent and nature of your reaction, could be covered under the Americans with Disabilities Act. Ask your employer about accommodations you may need if you are allergic to your coworkers' perfume.
If you have perfume allergies, the lingering fragrance in the air or on your skin can cause a plethora of unpleasant symptoms. If you have perfume allergies, the lingering fragrance in the air or on your skin can cause a plethora of unpleasant symptoms. Perfume allergies can affect your respiratory system even when you are not wearing the perfume yourself.
- Dermnet NZ; Fragrance Mix Allergy; Vanessa Ngan; November 2010
- Job Accommodation Network; Accommodation and Compliance Series: Employees With Fragrance Sensitivity; Tracie DeFreitas Saab; September 2008
- "Journal of Environmental Health"; Prevalence of Fragrance Sensitivity in the American Population; S. Carress et al.; March 2009
- MayoClinic.com; Allergy Skin Tests; April 2011
- Jupiterimages/BananaStock/Getty Images


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Ran a half-marathon this past weekend in one of the most gorgeous towns in Nova Scotia, Wolfville.
Didn't do too bad at all in regards to time, met my sub 2-hour goal at 1:52:13 and set a couple of PRs
Originally, I had registered for the marathon but I really didn't feel my training warranted it. The biggest goal I've yet to conquer in training is the 20 mile run and I want at least two of them under my belt before I attempt the 26.2.
I'm registered for the Houston Marathon in 2017, I figure over the next 14-15 weeks I can squeeze in a few quality long runs.by


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- Details
The router, for its simple design, is one of the most versatile tools you can own. You can shape decorative profiles, cut grooves, flush-trim, raise panels, and cut almost any joint.
In the Complete Illustrated Guide to Routers, youll learn how to unleash this versatility by choosing the appropriate bit, and guiding the cut in the proper manner. Youll also learn that while a multitude of bits are available, a few essential bits will enable you to accomplish many of your routing tasks.
More than 800 photo and drawings show you how to use and care for your router and how to get the most from it. In addition to mastering the use of your router, youll also learn about router tables, and how to make one that works perfectly in your shop.
- Additional Information
Additional Information
SKU FWW71070827 Table Of Contents Section 1: Choosing Routers and Accessories
Making a Custom Baseplate
Making a Straight-Sided Baseplate
Constructing an Edge Guide
Router Maintenance
Section 2: All About Bits
Changing Bits
Changing Bearings
Adjusting a Stacking Bit
Section 3: Router Tables
A Simple Fence
A Jointing Fence
An L Fence
Zero-Clearance Fence
Support Stand
A Two-Dollar Top
Making a Sled
Section 4: Common Cuts
Plunge Cut with Edge Guide
Internal Cut with Guide Bushing
Baseplate as Guide
Bearing as Guide
Making Stop-Cuts
Shaping Edges
Shaping Narrow Ends
Using a Starting Pin
Cove Cut on the Router Table
Routing Small Parts
Section 5: Routing Edging and Molding
Bullnose in Two Cuts
Edge Bead
Edge with Fence
Beveling Curved Edges
Molding on Face
Complex Molding
Complex Molding II
Built-Up Molding
Arched Molding Face
Arched Molding Edge
Section 6: Flush-Trimming
Flush-Trimming Face Frames
Flush-Trimming a Curve
Flush-Trimming Interior
Section 7: Router Joinery
Stopped Groove
Panel Groove
Two-Pass Groove
Tongue and Groove
Rabbet with Straight Bit
Dedicated Rabbet Bit
Lap Joint
Freehand Routing Dovetails
Shopmade Dovetail Jig
Sliding Dovetail
Half-Blind Dovetails with Porter Cable Omni Jig
Through Dovetails with Katie Jig
Half-Blind Dovetails with the Akeda Jig
Glue Joint
Tenon with Jig
Tenon on the Router Table
Lock Miter
Splined Miter
Birds Mouth
Box Joint
Section 8: Doors and Drawers
Door Bit Set
Reversible Door Bit
Adjustable Door Bit Set
Coped Mortise and Tenon
Arched Door with Cope and Stile Bits
Sash Door
Arched Light Sash Door
Raised Panel
Raised Curved Panel
Lipped Door Edge
Lock Mortise
Sliding Dovetail Drawers
Section 9: Routing with Templates
Internal Cut
Curve with Template
Flush-Trimming Tight Curves
Internal Rabbet with Template
Corner Shelf
Scalloped Top
Section 10: Special Shaping Operations
Pilaster with Handheld Router
Small Stock on Router Table
Fluted Quarter Columns
Routing a Dished Tabletop
Intro The router is undoubtedly one of the simplest of woodworking machinesbasically comprising just a motor, a base, and a collet. And yet it is one of the most versatile tools you can own. Back when the router was first invented, it was used primarily for shaping decorative profiles along the edges of tabletops and drawer fronts. It's still a great choice for those tasks, but the truth is, it can do a lot more, including grooving, flush-trimming, raising panels, and cutting almost any joint, including the all-important mortise-and-tenon and dovetail joints. In fact, the router can create all of the joinery necessary to make entire assemblies such as doors and drawers.
Unleashing all this versatility basically depends on two things: using the appropriate bit, and guiding the cut in the proper manner. Thats a bit of an oversimplification, of course, but it really is at the heart of the matter, as I'll show you in this book.
For example, if you flip through the pages of any router bit catalog, you're sure to become overwhelmed by the assortment of bit styles and sizes, which range from simple straight bits to large, complex molding bits. However, you'll find that a judicious selection of a few essential bits will enable you to accomplish many of your routing tasks.
As for guiding the cut, I'll show you a range of options, including using the edge of the router base, fitting a bushing to the opening in the base, or using a guide bearing on the bit. You can also choose to attach a fence or edge guide to the base. For some tasks, such as excavating for hardware, you might choose to simply guide the router freehand to remove much of the waste stock, completing the job with hand tools.
Another option is to use a jig or router table. No other woodworking machine lends itself more to the use of jigs or table-mounting than the router. Many commercial jigs are available to help you perform simple or complex operations, but you can also construct jigs yourself. Router tables open up a whole other realm of possibilities, effectively turning the router into a stationary machinea mini-shaper that's capable of routing large-scale jobs such as door panels. Although a table-mounted router lacks the power of a shaper, it's more versatile and economical, making it well suited to small-shop woodworkers on a limited budget.
So be prepared to expand your woodworking skills through the capabilities of this most remarkable tool. It's my hope that this book will provide you with a thorough understanding of the router and what you can achieve with it.
ISBN 978-1-56158-766-7 Video No Author Lonnie Bird Publication Year 2006 Dimensions 9-3/16 x 10-7/8 Pages 240 Photo color photos Drawings and drawings Other Formats 77988 Cover Paperback Format Paperback
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Leather Food Dispenser (inc 12tubs) V0011
It's important to look after leather, especially when it regularly gets wet. Natural oils in the material can be washed out and if they're not replaced, the leather will crack. Periodically treating your boots with Leatherfood will rejuvenate the leather and maintain its water resistant qualities.
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Wilmington, NC - Cape Fear women's soccer (6-1) won its second game on the same day, defeating Howard Community College (2-4) by a score of 1-0.
Because a school had to drop out of the Port City Classic, Cape Fear filled in for the final match of the tournament. It meant an incredibly quick turnaround, however, as the Sea Devils had finished their regularly scheduled game against Oxford College of Emory just 30 minutes prior to tip-off.
"Every single player on this team played a huge role in helping the team earn positive results today," said head coach Ryan Deppa. "They played three college games in just over 24 hours on turf [and] in major heat. Absolutely crazy."
Despite virtually no rest between games, the girls were ready. Goals were hard to come by, but the Sea Devils found the back of the net in the 70th minute as Carly Higgins scored off a header thanks to an assist from Tallison Brainard.
The goal gives Higgins her 10th goal of the season, while Brainard earned her fifth assist, which puts her tied with Kaitlin Plienis for the most assists on the team.
Additionally, goalkeeper C.J. Garvey earned her sixth shutout of the season.
Coach Deppa was extremely proud of his team after the game.
"[Cape Fear] showed so much heart, so much toughness this weekend, so much character. They represented CFCC, Wilmington, their teammates, our program, their family in such a great way today."
"To do what they just did today, versus two solid and well coached programs, says a great deal about them. I am sure everyone that came out and supported them is full of pride. This team has been up against it, and they proved once again that together they do some special things."
Coach Deppa hopes his team's achievements spread around campus.
"I sure hope word spreads about these kids and the crowds continue to grow as the season moves forward. They are fun to watch."
The Sea Devils are scheduled to play next on Friday, September 14th as they hit the road to take on Wake Tech Community College. Gametime is scheduled for 2:30 p.m.
Courtesy of Nick Denning


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New therapy that U-M neurologist helped develop will undergo Phase I trial at Emory University
U.S. Food and Drug Administration gave the green light Friday for a clinical trial of a new stem cell treatment for amyotrophic lateral sclerosis (ALS). University Michigan neurologist, Eva Feldman, M.D., Ph.D., will be the overall principal investigator for the first human clinical trial of a stem cell treatment for ALS, a fatal neurodegenerative disease.
The FDA approved an Investigational New Drug application from Neuralstem, Inc., a Rockville, Md.-based biotech company, to test the safety of a treatment in which patients will receive injections of the company's patented neural stem cells at multiple sites along the spinal cord.
Director of the U-M ALS Clinic and the Director of the Program for Neurology Research & Discovery, Feldman worked with a team of neurologists and with Neuralstem Inc. to develop the protocol for delivering the stem cells into the spinal cord of patients.
The Phase 1 trial to determine the safety of the treatment is expected to take place exclusively at Emory University in Atlanta, Ga., subject to approval by its Internal Review Board.
"We are very excited about this clinical trial," said Feldman, the DeJong Professor of Neurology at the U-M Medical School. "This is a major stride forward in what still could be a long road to a new and improved treatment for ALS.
"ALS is a terrible disease that ultimately kills by paralysis. In work with animals, these spinal cord stem cells both protected at-risk motor neurons and made connections to the neurons controlling muscles. We don't want to raise expectations unduly, but we believe these stem cells could produce similar results in patients with ALS," Feldman said.
ALS, also known as Lou Gehrig's disease, affects about 30,000 Americans. It progressively destroys the neurons that control voluntary muscles, leaving affected people unable to move or speak. There are no known treatments for the disease that slow its progression.
The trial will ultimately consist of 18 ALS patients with varying degrees of the disease. The FDA has approved the first stage of the trial, which consists of 12 patients who will receive five-to-ten stem cell injections in the lumbar area of the spinal cord. The patients will be examined at regular intervals post-surgery, with final review of the data to come about 24 months later.
Jonathan Glass, M.D., director of the Emory Neuromuscular Laboratory, is expected to be the site principal investigator for the trial.
Individuals interested in further information on the trial should contact Emory Health Connection, 404-778-7777, or 1-800 75EMORY, or go to www.neurology.emory.edu/als
Institutional review boards at U-M and Emory University must first approve the protocol.
If Phase I results are favorable, the treatment will need to prove effective in Phase II and III trials and win final FDA approval before it can be available for public use.
Funding: Neuralstem, Inc. plans to conduct and fund the Phase I trial of its patented technology.
Patents/conflict disclosures: Dr. Feldman has no financial interest in or financial arrangement with Neuralstem.
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Vic Bourassa , Proprietor
Growing up in Worcester, Massachusetts, Victor Bourassa learned winemaking from one of his Italian-immigrant grandfathers and inherited an entrepeneurial spirit from the other. The former made wine from grapes that he purchased at street markets; the latter built a grocery store from the ground up. Vic's father eventually ran the store, operated a gas station and worked as a contractor-builder. Along the way, Vic learned to appreciate the value of hard work, optimism, integrity and tradition.
After serving in the Navy in Vietnam, Vic moved to Southern California. He earned his commercial pilot's license from Orange Coast College, then made a career out of working in real estate and start-up companies. He visited the Napa Valley for the first time in the early 1980s and moved there permanently in 1996. He worked in a couple of wineries, took wine-related classes at UC Davis and Napa Valley College, and became an avid home winemaker and president of the Napa Valley Home Winemakers Association.
Then, in 1999, lightning struck. Vic recalls the bolt out of the blue.
"Robert Mondavi came to my house, introduced by a friend. We sat down in my backyard with some bruschetta and a bottle of 1998 Pinot Noir. I had made the wine in a funky little hand press. I bottled it that day and a made a label on my computer. So there we were, Robert Mondavi and I, drinking my wine and eating bruschetta.
"I had a glass, and he had one. Then, he had another…and another. After he finished the bottle, he declared that I should be making wine commercially. When I said I thought it was too late to start, he told me that he hadn't begun until he was 52, and look what he'd accomplished. He basically took away my excuse – at 50 years of age."
In October 2003 Vic released his first commercial vintage, the 2001 Bourassa Harmony3, a complex Bordeaux-style blend made from valley-floor Cabernet Sauvignon and Merlot, and Howell Mountain Cabernet Franc.
Today Vic continues to grow Bourassa Vineyards while raising a glass to toast his straightforward philosophy: Celebrate life!
Gary Galleron, Winemaker
Gary Galleron grew up playing in the vineyards along Galleron Road, the street named for his French-immigrant grandparents who settled in the Napa Valley in 1918. He has worked in the family vineyards since he was a child, learning every aspect of the wine industry literally from the ground up.
Later attending and graduating from Cal State University Fresno with a degree in viticulture and enology in 1976, Gary went to work with Mike Grgich at Chateau Montelena gaining invaluable experience. Since then, he has produced award-winning wines for some of the most prestigious wineries in the valley, including Whitehall Lane, Grace Family, Hartwell, Vineyard 29, Del Dotto Vineyards, Seavey and William Harrison Vineyards.
Gary's passion for his work ("It's not my job, it's my life.") has led him to seek out the best grapes from the finest vineyards in the Napa Valley. He remains a hands-on artisan who is among the Valley's most respected winemakers. Soft-spoken and more inclined to talk about the value of high quality fruit than of winemaker wisdom, Gary continues crafting award winning wines for Bourassa Vineyards.