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This is a mildly revised and updated version of Peepin' Out, originally posted in May, 2014.
Recently, somehow, word got through to me, that Peeps, those brightly colored marshmallow bunnies and chicks, would now be sold year-round. I can't say if I even knew that those little cuties only peeped out on the market for a relatively short period of time each year in order to celebrate the Resurrection, but apparently this change was newsworthy.
Truth be told, I am really naive and poorly informed on certain things, like candy and religion. I have been confused for decades between Cabbage Patch Dolls and Sour Patch candies–I think that is what they are called. During nutritional consults, I confess that I have uttered the words, "Do you eat like Cabbage Patch Doll candies?" Not just randomly of course, but in the context of an assessment when I am trying to professionally interpret someone's intake while sounding like I know what I am talking about.
Somewhere halfway between childhood and deciding to become a nutritionist, I managed to wean myself off of my predilection for sugar woven into various seductive forms. Maybe the end of my relationship with Peeps coincided with my commitment to a vegetarian diet. Eating anything with a face became more distasteful, including these adorable balls of gelatin congealed fluff. I have managed to avoid them for a long while now, except for a time where a co-worker enjoyed flaunting her love of them in front of me like the Adoration.
But, upon hearing the news that Peeps would be popping up in stores on a daily basis, I reacted like Puxatawny Phil seeing his shadow on that fateful Groundhog's Day. Down into the burrow, I hastily fled. Just when I thought that maybe things were getting a little better regarding our capacity to ameliorate incoming incarnations of sugar, this information startled me. To soften the blinding light of neon-colored commercialism, I had no choice but to go into the dark place below.
By candlelight, I read the small print. Peeps are stewarded by the Just Born Company in Bethlehem, Pennsylvania. According to the website, the wonderful combination of sweet colored sugar and fluffy marshmallow creates an unforgettable taste experience. And, furthermore, it states a great candy isn't made, it's just born. Jesus! Don't these guys realize how bunnies multiply and that chicks are no slackers either when it comes to population growth? I guess they do. Apparently, 5.5 million Peeps are born each day!
This pronouncement of a seemingly immaculate conception in Bethlehem, rather than some sticky mess, presented a whole new ball of carnauba wax–one of the ingredients in Peeps along with sugar, corn syrup, gelatin, potassium sorbate, natural flavors and red 3, blue 1, yellow 6, or yellow 5 depending on the color. With 6.8 grams of sugar, each Peep is endowed with 1.5 (rounding down) teaspoons of essentially pure sugar–the kind that sends our bodies into metabolic-altering, insulin-demanding, fat-storing sugar shock.
In my quest to find out more about this situation, I was forced back above ground. Donning sunglasses, my research led me to my local national chain drug store where I made a few laps around the multi-aisle candy section disguised as a normal sugar craving person. I was forced to blow my cover by asking the clerk where the Peeps were. She reacted as if I must be from another planet. I did not bother to defend my citizenship as an earthling and neither did I explain the whole groundhog thing. But I did say my query had a scientific purpose–or something like that. Obviously, Peeps were not to be found after Easter. I was six weeks too late.
But, I said, I thought they were available all year now, in a widening array of flavors. She had not gotten that memo. However, she instructed me to go to the company website if I wanted more information. I thought that was funny. But, it was actually a good idea. (This year I got to see how the little sweeties are born.)
She did add though that she had somewhat recently gotten her little daughter some watermelon ones, so maybe I was right. I stiffened like a stale Peep. Like Catcher in the Rye's Holden Caulfield who deemed himself the protector of childhood innocence, perhaps I take my influence as a nutritionist of the people and for the people a bit too seriously. In my head, I am charged on a daily basis to personally obliterate obesity, or on a larger scale to clean up this whole nutritional mess and its adherent ills.
I liked the care and assistance the drug store clerk had given me despite her initial recoil, and now by association, I cared about her daughter. Could I not issue a global recall of these wolves in chicks' clothing candies due to salmonella poisoning, avian flu or something to save the children? My usual quandary about how to reconcile the business of capitalist markets and the public health smacked me in the face along with another more subtle underlying dilemma–who am I to take sugar from a baby? Don't they need some sweetness in this cruel harsh world?
Well, I figured it was time to move back up. As by now, spring had finally arrived in these parts after the long, extended rodent-predicted winter, I decided it should be safe to step back into the sunlight.
Oh well. Send word. Let me know what you think or just say hi. I miss you. And, if you are needing a healthy, bunny-approved, Easter treat, look no further than Naked Food Magazine's 5-minute Carrot Truffles.
In health, Elyn
P.P.S. For the winners of the 2018 Peeps diorama contest, check this out. And, oh my goodness, it looks like just this week there is some trouble down on the peeps farm regarding the company's employee pension plan.
MyPlate Haiku
Lagoon watercress Peppers my tongue With spring joy. by Roxanne


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Charles Lewis Sizemore, CFARobertson Wealth Management, LLC
DescriptionCharles Lewis Sizemore, CFA is the founder and Chief Investment Officer of Sizemore Capital Management LLC, an RIA firm based in Dallas, Texas offering investment advisory services to clients, including managed accounts, ETF portfolios, equity portfolios, IRA and Roth IRA management, retirement planning, and educational...Read Full Bio planning among other services. Mr.Sizemore's specialties include investing for current income with high-dividend stocks, international investing, and tax-managed investing. Mr. Sizemore has been a repeat guest on Fox Business News, has been quoted in Barron's Magazine, The Wall Street Journal and The Washington Post, is a contributor to Forbes Moneybuilder, and has been featured in numerous publications and well-reputed financial websites, including MarketWatch, TheStreet.com, and InvestorPlace. Mr. Sizemore holds a master's degree in Finance and Accounting from the London School of Economics in the United Kingdom and a Bachelor of Business Administration in Finance with an International Emphasis from Texas Christian University in Fort Worth, Texas, where he graduated Magna Cum Laude and as a Phi Beta Kappa scholar. Mr. Sizemore maintains the Chartered Financial Analyst (CFA) designation in good standing.Read Less
other namesN/A
Other FirmsSizemore Capital Management, LLCManaging Member
doing business asN/A
7557 Rambler Road SUITE 700
Dallas, TX 75231
Advisor Services
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No timeline events available.
|Robertson Wealth Management, LLC.
|2 years, 8 months
|May 2017 - Present
|Dent Research
|5 years, 4 months
|Sep 2014 - Present
|Sizemore Capital Management
|11 years, 11 months
|Mar 2008 - Present
|Hs Dent Investment Management
|6 years, 3 months
|Sep 2004 - Dec 2010
Designations & Memberships
Chartered Financial AnalystDesignationWidely considered the gold standard for investment professionals, this six decade old charter is only given to designees who can demonstrate competence, integrity, and dedication to the field of investment management.
Articles and Answers
Insights by Charles Sizemore
Investing in Preferred Stock: What You Need to Know
Published 2012-07-26 19:13:56
Spotting a Value Trap
Published 2012-06-18 19:52:27
European Dividend Stocks: What You Need to Know
Published 2012-06-06 11:27:44
The Ins and Outs of International Investing
Published 2012-05-23 05:31:39
Beware of Chasing High Dividend Yields
Published 2012-05-16 19:01:59
Choosing the Right Dividend ETF
Published 2012-05-16 18:51:22
*Articles are published by advisors without compensation.
AnswersAsk a financial questionAsk a question
|Where should I put my riskiest holdings, taxable or tax-sheltered portfolio?
There are a couple points to consider here:What is the time horizon of these riskier investments? If these risky investments are ones that you intend to buy and hold for a while, it makes more sense to put them in a taxable account and to save your tax-deferred accounts for income-oriented inves...  (more)
Answered Jun 2012
|If futures and options are such risky investments, in what situations does it make sense to invest in them?
Futures have little use as an investment vehicle for the vast majority of investors, unless you happen to be a farmer or miner hedging your production (and I KNOW that the vast majority of Brightscope readers are farmers looking for advice on how to hedge their corn crop...or not).Options, however...  (more)
Answered Jun 2012
|I'm in my mid-twenties and am looking for advice on how to allocate my assets properly. What's the best type of financial adviser to look for in this process.?
The comments about choosing a fee-based advisor are spot on. When an advisor is paid a fee that is based on a percentage of the assets managed, they have every incentive to grow your nest egg responsibly without taking undue risk. Here are a few other items to consider:Make prospective advisors...  (more)
Answered Jun 2012
|What is an appropriate fund management fee percentage?
A higher-than average fee on a mutual fund or ETF is a red flag but not always a deal killer. The question you should ask yourself is "What does this manager do that is fundamentally different than the cheaper competition?"If the manager is a large-cap growth manager that closely tracks the S&P...  (more)
Answered Jun 2012
|Pension payout options?
Sit down with a pen and paper (or spreadsheet; I'm a little old fashioned) and play with the numbers. How much in annual income does your current pension promise? What rate of return would you have to generate on your investments to equal that payout?You basically have two options if you take th...  (more)
Answered Jun 2012
|Do all banks offer lines of credit for co-op apartments?
If you are looking to buy a co-op or condo, the financing will generally be a traditional mortgage. There is nothing unusual or extraordinary about this.However, when looking at purchasing this kind of property, there is one VERY important question you should ask: Are there homeowners association ...  (more)
Answered Jun 2012
|Do you tend to recommend mutual funds, ETFs or individual stocks as a general rule for individual investors?
It depends on the investor, the type of account the funds are held in, and how often you intend to add new funds, but here are a few guidelines to consider:If you intend to reinvest dividends and make regular new contributions, a low-cost index fund is going to be the best option for most investo...  (more)
Answered May 2012
|How do I short a stock?
There is nothing "wrong" with shorting a stock, so long as you understand the risks involved. When you short, you are moving out of the territory of investing and into the territory of trading, and it is a different mentality. Here are a couple things to consider:Remember, the most stocks follo...  (more)
Answered May 2012
|Solo 401k?
The SEP IRA is generally going to be a better option for most small business owners. None of the other retirement options, including the Individual 401k, offer the same flexibility or are anywhere close to as easy to administer. And as a small business owner, you don't want to be wasting your time...  (more)
Answered Jun 2012
|How can i find my 401k plan and cash it in?
If you no longer work for the company, it probably makes sense to move the 401k. But "cashing it out" is a very different matter. It is almost always a better idea to roll the old 401k plan into a rollover IRA or into the 401k plan of your current employer unless you need the cash for immediate pu...  (more)
Answered Jun 2012
|I'm trying to decide where to invest next. I'm maxing out my employer matched 401k, maxing out a traditional IRA, and will soon have an emergency fund in a savings account that I'll continue to add to every paycheck. Where to next?
First, congratulations. The fact that you have maxed out your 401k and IRA put you well ahead of the vast majority of Americans. This shows discipline and a willingness to live below your means, both of which are commendable. As for investment options, the answers given above about variable annui...  (more)
Answered Jul 2012
|Are Dividend Reinvestment Plans good investment tools?
I love DRIP plans for long-term wealth building, though it can be cumbersome to open DRIP plans with multiple companies, which is what you would need to do in order to have anything resembling prudent diversification. A better option might be to open an account with a broker that offers free divide...  (more)
Answered Jul 2012
|Should I set up an IRA for my 14 year old?
Your daughter will likely thank you someday. Even though her current earnings are modest and unlikely to be sufficient to max out an IRA, you would be teaching her a valuable lesson about investing for the future and the compounding of dividends and interest. It is the good habits and philosophica...  (more)
Answered Jun 2012
|I will be retiring in one year at age 63. I have a good retirement package from my employer and have managed my 401K plan fairly well to current balance of $1.1M. 90% of my 401K is invested in a stable income fund at 3.55%, 10% is in company stock which has been flat for the past couple of years.
Good answers here. I would only add that 3.55% is an outstanding return for a stable value fund these days. Before you pull your money out of the 401k and roll it into an IRA, consider what your other investment alternatives would be. You will hard pressed to find a better yield without assuming ...  (more)
Answered Jun 2012
|Where can I get icome from my IRA???
I am retired at 56 and my husband is 57??
If you can wait until 59 1/2 by depending on other sources, then you certainly should. There is no reason to pay an early withdrawal penalty if you can avoid it.David's explanation above of using the annuity exception is correct, but you should have a lengthy chat with your financial advisor firs...  (more)
Answered Jun 2012
|What would the impact of a Mitt Romney presidency be on the economy? Is he considered pro-growth?
At the margin, a Romney administration might be a little more pro-growth than an Obama administration, but probably not enough to matter all that much. Here are a couple points to consider:The president of the United States has little power over the key issues driving the economy and capital ma...  (more)
Answered Jun 2012
|Forex - Investing in the Euro after the Greek elections?
Let me present it to you like this. You don't see very many old currency traders. With very few exceptions, they tend to burn out young and quit the business. The shot-termism and the wild volatility take their toll on you over time. Frankly, currency trading is bad for your health. There are s...  (more)
Answered Jun 2012
|Is investment in raw land considered a low risk, moderate or high risk investment?
Some things to consider about the riskiness of an investment in raw land:A value investor would tell you that the riskiness of an investment is first and foremost a function of the price paid. If you pay too much for ANY investment--be it a stock, a bond, or a tract of land--you put yourself at ...  (more)
Answered Jun 2012
|When should I have a financial adviser help with my divorce?
You should keep your financial advisor in the loop throughout the process for several reasons.When dividing financial assets, you can generate taxable gains if you sell appreciated stock or other investments. This should be planned properly to avoid getting both you and your ex-spouse slammed co...  (more)
Answered Jun 2012
|I have 401k's from previous job (wife and I) Can someone convince me that I shouldn't cash out and buy (2) houses that will generate me$2200 a month in rent..$1700 net approx? We also max out 2 new company 401k's so we still we be in market. Need allot of money in 401k at taking out 4% to get $170
Given the prices on offer in some markets, I agree that a strong case can be made for buying rental properties as a part of a diversified retirement plan. Warren Buffett--a man who has forgotten more about stock market investing than most money managers will ever know--said publicly that Berkshire ...  (more)
Answered Jun 2012
*Answers are submitted by advisors without compensation.
Advisor Links
Charles Sizemore on the StockTwits Blog Network
Charles Sizemore brings his investment ideas to the StockTwits Blog Network.
Worried About Inflation? I'm Not
In a world of deleveraging, inflation is not your primary concern.
Charles Sizemore in the Media
Charles Sizemore's recent appearances on TV, radio, and in print.
Sizemore Capital Allocation Change: Dividend Achievers
Sizemore Capital is making a strategic allocation shift for all ETF portfolios with U.S. large cap exposure. This affects the Tactical ETF Portfolio and the Strategic Growth Allocation.
Dividend ETFs for Growth and Income
Guide to choosing the right dividend-focused ETF.
Charles Sizemore on the MarketWatch Trading Deck
Charles is a regular contributor to the MarketWatch Trading Deck
Charles Sizemore on Forbes MoneyBuilder
Charles Sizemore offers his insights to the Forbes MoneyBuilder
The Sizemore Investment Letter
Charles Sizemore weaves traditional value investing with his unique blend of history, demographics, and global current events into each issue of the Sizemore Investment Letter.
Licenses & Conducts
U.S. Securities and Exchange Commission
license statusRegistered
as of dateJun 1, 2017
license statusNot registered
as of dateN/A
Review the status and details of the disclosures noted above using the SEC's Investment Advisor Public Disclosure website:
Robertson Wealth Management, LLC
Last updated on Jan. 16, 2020
$34.1MTotal Assets Under Management
N/ATotal Assets Under Advisement
$283.9KEstimated Average Account Balance
Fee Only Advisor
This advisor has certified that they are compensated soley by their clients, and do not accept commisions or compensation of any kind based on the products they recommend.

subset: commoncrawl


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The lung transplant program provides two-hour educational seminars approximately three times per month (see schedule below), and lung transplant candidates are required to attend 12 lectures per year. There are usually two lectures per seminar. These seminars offer invaluable information to help you and your loved ones to learn more about transplant and to know what to expect. The professional staff of the lung transplant team provides interactive lectures about organ donation, post-transplant medications, the role of exercise, organ rejection, psychological factors, nutrition, research in transplant, ethics, and infection control.
Twice a year we offer a two-hour panel comprised of post-transplant patients that give pre-transplant patients an opportunity to hear their experiences. .Post-surgical patients are encouraged to participate, not only because the sessions continue to be helpful but also because they can offer a unique and very helpful perspective to candidates waiting for a donor organ.
The program also offers non-mandatory, specialized support group meetings for: (1) caregivers — those responsible for seeing to it that the recovering transplant patients are taking their medications, moving about and getting the necessary care they require at home — and for (2) pre-transplant patients to give them an opportunity to share their experiences and concerns with one another. They take place on Mondays, from 11:30 AM-12:00 PM, and they are facilitated by the social worker.
Lung Transplant Program Educational Seminar Meetings
Download the 2019 Meeting Schedules Flyer »
Please Note: Patients Are Required to Attend 12 Seminar Meetings per Year.
One visit counts for 2 seminars.
January – June 2019
Mon, Jan 14th
12:00-1:00 PM: Lung Allocation Score by Hanyoung Kim, RN
1:00-2:00 PM: Readmissions and Hospitalizations by Tamar Gardner, RN
Tues, Jan 29th
3:00-4:00 PM: Types of Donors by Rachael Begler, RN
4:00-5:00 PM: Post-Transplant Hospitalization by Daryle Blackstocke, PA
Mon, Feb 11th
12:00-1:00 PM: Acute and Chronic Rejection by Lori Shah, MD
1:00-2:00 PM: Importance of Caregiving
Tues, Feb 26th
3:00-4:00 PM: Insurance and Financing Transplant by Stemmijoi Haynes, Fin. Coord
4:00-5:00 PM: Fear and Courage in Transplant by Sasha Storaasli, LCSW
* Please note this seminar will take place in Heart Center, Room 1&2
Mon, Mar 11th
12:00-2:00 PM: Post Transplant Panel by Lung Transplant Recipients
Tues, Mar 26th
3:00-4:00 PM: Life After Transplant by Maggie Carroll, PA
4:00-5:00 PM: Exercise in Transplant by Nicole Pieszchata, PT/Aimee Layton, PhD
Mon, April 8th
12:00-2:00 PM: Post-Transplant Medications by Jenna Scheffert, Pharm-D
Tues, April 23rd
3:00-4:00 PM: Frequently Asked Questions by Selim Arcasoy, MD
4:00–5:00 PM: Diet and Transplant by Brenda Klein, RD, CDN, CDE
Mon, May 6th
12:00-1:00 PM: Lung Allocation Score by Hanyoung Kim, RN
1:00-2:00 PM: Non-Pulmonary Complications of Transplant by Hilary Robbins, MD
Tues, May 21st
3:00-4:00 PM: Things to Know Once You're Listed by Rachael Begler, RN
4:00-5:00 PM: Meditation and Healing in Transplant by Rev. Seigan Ed Glassing
Mon, June 3rd
12:00-1:00 PM: Acute and Chronic Rejection by Lori Shah, MD
1:00-2:00 PM: Readmissions and Hospitalizations by Tamar Gardner, RN
Tues, June 25th
3:00-4:00 PM: Frequently Asked Questions by Selim Arcasoy, MD
4:00-5:00 PM: Post-Transplant Hospitalization by Diana Walsh, PA-C
All meetings will take place in:
Vivian & Seymour Milstein Family Heart Center
173 Fort Washington Avenue, New York, NY 10032
Myrna Daniels Auditorium
Get Maps & Directions »
EXCEPT the February 26th seminar which will take place in Heart Center rooms 1&2.
Please bring sufficient oxygen to last the duration of your trip to the hospital and return home.
If you need to run out and need to borrow from the Milstein Security Desk, please return it to the safety containers when finished.
This Schedule is subject to last minute changes. It is advised to contact your Social Worker or check Social Worker voicemail prior to the meeting:
Sasha Storaasli, LMSW 212.305.0665
Bailey Petry, LMSW 212.342.1364


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How Can You Get Your Business On The Map? Check This Out…
Are you looking for ways to connect with the world?
In our day and age, technology is the ultimate tool of any trade. Whether it be dealings of web design or internet marketing, finding out how to get your brand to the people is imperative to conducting smart business.
For good web design, and some of the best internet marketing, you have to find whatever niche market needs to be filled. For example, if you're selling health services, you'd want to have your work advertised to people searching for wellness centers and medical care. To get yourself out there, you need to know your audience; better yet, you need to know what your intended audience is yearning for. After that, it's just a matter


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Full Length of The Clan in High Definition FormatNow you can enjoy The Clan in top quality with duration 110 Min and was published in 2015-08-13 and MPAA rating is 6.
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- Cast of movie :Guillermo Francella (Arquímedes Puccio), Peter Lanzani (Alejandro Puccio), Liliana Popovich (Epifanía Puccio), Gastón Cocchiarale (Maguila Puccio), Giselle Motta (Silvia Puccio), Franco Masini (Guillermo Puccio), Antonia Bengoechea (Adriana Puccio), Stefanía Koessl (Mónica)
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|I really like my Daddy's Day tin can planters!
Make Your Own Tin Can Planter
You will need:
- An empty, clean tin can
- Hammer and a nail
- Something to cover the can with
- Glue
- Spray varnish & gloves
- Compost
- Plant or seeds
To make:
1. Find a tin can which you like the size and shape of. I chose some different sizes to make a nice collection but one can look just as good. Ask a grown up to make sure its all nice and clean and that there are no sharp edges.
2. You will need drainage holes in your can so ask a grown up to turn it upside down and using the hammer and nail add a few holes to the bottom.
|Be careful not to hit your fingers Auntie Alison!
3. Now you can personalise your tin can with whatever you want. Some ideas include one of your own drawings, paintings or hand prints, a relevant piece from a magazine or newspaper or some nice wrapping paper.
|Euan and I did pretty paintings for some of our planters.
We also used newspapers and comic strip wrapping paper.
4. Carefully measure your paper so that it wraps perfectly around your tin can with a little bit extra for gluing down.
|I find sticking your tongue out helps you
concentrate on getting this tricky stage just right!
|Carefully glue the edges of your paper
6. Take your tin can outside and ask a grown up to spray it all over with spray varnish. This will waterproof the paper so the planter can sit outside and not be ruined. Remember to use gloves when spraying and always spray outside or in a very well ventilated area.
|Ask a grown up to spray outside and use gloves
7. Once the varnish has dried you can fill your can with compost and plant your seeds or plants. We always have some lovely plants and seeds that are perfect for adding to a mini planter kicking around the garden or shed and you can easily divide some plants such as sempervivums to create new free plants! Herbs are a lovely addition or dwarf plants and cacti can look great too.
|Euan and I chose a selection of different
cans, papers and plants for our planters
If you are struggling for time you can skip steps 3-6 and keep your tin cans with the plain metal finish which looks great. If you find teeny plants in pots (some garden centres sell them) you can skip the drainage holes and compost part too and just pop the pots straight into the tin cans. Remember they will rust if they go outside so they would be better kept on the windowsill with herbs or indoor plants. Or you could paint them bright colours or varnish them if you want to place them outside.
|The original metal cans look great too.
So, there you go, a Daddy's Day tin can planter, a lovely memento for years to come.
Hugs & kisses,
A big thank you to Apartment Therapy for the inspiration for this blog.


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Bending Made Easier with Amada Press BrakePosted on May 29, 2017 by Hygrade Laser Profiling, in News
Bending has been made easier with the Amada HS1703 Press Brake, brand new to Hygrade Laser Profiling.
The Amada HS Press Brake series is part of a new line of dynamic bending solutions. With extra features including a touch screen NC based controller, this innovative bending technology continually monitors and self-regulates bending requirements.
Already benefitting from the efficiencies the machine brings, we have much more capacity to bend heavier plates, with the machine providing a 3.0m bend length.
The press brake comes equipped with an energy saving drive system made from a frequency inverter that controls the motor pump which only operates when necessary. This significantly reduces environmental footprints saving 20% more energy, less oil consumption, lower noise levels, less time spent maintaining the machine and increased reliability.
To find out more, please get in touch.


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188 Technology Dr. Suite N, Irvine CA 92618
We're open Monday – Friday, 8 a.m. – 7:30 p.m. PST
Frequently Asked Questions
Please read our FAQ before sending us a message.
Which payment methods are accepted on YouChakra.com?
We accept all major credit cards.
How long will delivery take?
Delivery varies by location. Generally within 5-7 days.
How safe and secure is my data on YouChakra.com?
All data is transmitted via SSL secure 128-bit encrypted connection. We do not store any of your personal data.
What exactly happens after ordering?
You will receive a confirmation email with further information regarding your order and shipping times.
Do I receive an invoice for my order?
Yes, you will receive an email invoice. 🙂
Send us an email


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Today, New York Times executive editor Bill Keller informed the staff that deadlines will be moved up a half hour, beginning in January. Full memo is after the jump.
From: Bill Keller
Date: Nov 30, 2006 9:00 AM
Subject: To the Staff
To the Staff:
Come January we'll be moving our evening deadlines a half-hour earlier.
Our circulation colleagues have argued that they'd be better able to retain existing customers (and get new ones at a lower cost) if they can guarantee that the paper will reach suburban subscribers' doorsteps by 5:30 a.m. Of course, it is just as important for our readers to get late news in the paper. After a lot of study and splitting-of-differences, we think we've found a way to do a bit of both.
First, we'll be moving all our evening deadlines 30 minutes earlier. This means the last pages of our two national editions will close at 9:30 and 11:30 and our city editions will close at 10:15, 11:30 and 12:30 (plus the goodnight postscript.) But there will be a twist: we will now put a ceiling on the number of papers that can be printed in those pre-midnight editions.
Historically our final edition, which closed at 1:15 a.m. was only received by at most 125,000 readers. This change means there will be between 335,000 and 385,000 copies printed after 12:30 pm, which makes up more than half of the total New York print order. Most of our readers in Manhattan and the boroughs will get a later paper than they've been getting.
We know there are many scheduled news events that do not fit into this new second-edition schedule. We've agreed that on those nights (such as during the State of the Union speech, on election nights, during the World Series, etc.) we can and will request later deadlines in advance.
And, as always, when major news breaks late in the evening,we will slow or stop the presses to get the news into as many papers as we can. Both the News Desk and our Production colleagues have lots of practice at that.
I don't want to kid you. We think later deadlines make better newspapers. That's why we pushed so hard for later closes throughout the nineties.(For the record, the new first city close of 10:15 still compares favorably with the 9:45 close we enforced a decade ago, and the 9 p.m. deadline in effect 15 years ago. And in those days readers did not have the option of checking our website for updates.) We think this is a compromise that minimizes the impact on timeliness of the printed paper, and actually means later news for many of our most loyal readers. And it's money that will not have to come from cuts that would impair our ability to cover the news.


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Dr. David R. Legates
Dr. David R. Legates (Climatologist) Delaware State Climatologist, Professor and director of the Center for Climatic Research at the University of Delaware.
"Scientific debate continues regarding the extent to which human activities contribute to global warming and what the potential impact on the environment might be. Importantly, much of the scientific evidence contradicts assertions that substantial global warming is likely to occur soon and that the predicted warming will harm the Earth's biosphere."
"Sea levels have been rising – in fact, they have been rising since the end of the last ice age 20,000 years ago – but there is no evidence of an accelerating trend." [that would be the end of the ice-age 9,000 years ago]
"In sum, the science does not support claims of drastic increases in global temperatures over the 21st century, nor does it support claims of human influence on weather events and other secondary effects of climate change."
Not [currently] the Delaware State climatologist and repeatedly told not to refer to that title by the Governor Ruth Ann Minner. The conflict between the post as representing the State and the Science and personal views is highlighted in this link. Currently a geography professor, ardent skeptic of AGW. Being one of only a few scientists that are skeptical and a minority opinion the few papers he has produced are superseded by the thousands of other papers. He may have a point but I would not trust a scientist that backs up his argument for intelligent design.
"We believe Earth and its ecosystems — created by God's intelligent design and infinite power and sustained by His faithful providence — are robust, resilient, self-regulating, and self-correcting, admirably suited for human flourishing, and displaying His glory. Earth's climate system is no exception."
Hardly the opinion of someone who looks at the evidence.
More on Legates and for a critque of his 2006 paper read this – the statement that the ice age ended 20,000 ears ago is a classic.
The present day scientific analysis of climate change states that there are no 'spatial' influences that can effect climate change. Recent NASA science has identified a significant spatial source of climate forcing. On the website http://www.whyclimatechange.net/ I provide scientifically based proof of spatial climate change influences using NASA, NOAA, and many other respected scientific resources. This phenomenon is occurring within the same time frame as the industrial revolution while defining jet stream behavior, climate change without extreme earth temperature variations, and the temporary transfer of ice from the Arctic to the Antarctic regions.
Atmospheric studies are crucial to understanding mankind's ability to alter earth's climate; however, to understand the primary spatial cause of the present day climate changes, as well as the atmospheric causes and the atmospheres ability to compensate for mankind's abuses, the research priorities must to be expanded.
I would very much appreciate your comments on my eight year study that supports the analysis as posted. My goal is to have the scientific community develop an expanded scope of climate change research that encompasses the primary spatial cause of climate change. Any suggestions, references, or comments to help me reach that goal would be very much appreciated. The expanded, and therefore more scientific approach to the analysis, is essential to understanding climate change. The humanitarian and financial implications are enormous. Rather than being captured in the politics of the myopic atmospheric approach; a sound scientifically developed program that identifies the true spatial cause of climate change provides better science and political arguments.
Thank you for taking the time to read this message.


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Women urinary tract infection problem, nowadays it's a great problem seen everywhere around us and women are suffering from these problems.
It's a major problem, so we should keep our knowledge about this. Only then, we can safe from us from this problem. As we are intended to help all of you and for giving you some important information, we are here. If you are a woman, this article is very important for you. Especially women face urinary tract infection problem, so every woman should know proper knowledge about this sickness. It is a serious problem and urinary tract infection problem some times make long term body problem. Today we will discuss about the urinary tract infection problem. Stay with us and know more detail.
What is The Urinary Tract Infections:
Shortly we can say urinary track information as UTI. It is such an infection that involves kidney, urethra or bladder. Before being eliminated from the body, urine passes through this structure. On the other part of the needle at about waist level kidney lie. They are pair of small organs. In our body kidney have some essential functions and include removing excess water and waste product and then eliminate them as urine.
Urinary tract infection is people who are exposed to some degree of risks. The very first thing you need to follow whenever you're afflicted by urinary tract infection or UTI is to drink plenty of water.
The infection can occasionally result from fungi or some parasites also. A urinary tract infection can happen at any among these anatomical websites. It occurs when a person's urinary tract becomes infected by E. coli. Should you be pregnant and create a urinary tract infection, you ought to receive your condition treated immediately. Urinary tract infections are a significant health problem and among the most often encountered infections within the body. Urinary tract infection in women is much more common than it is in men.
In the event the infection is just in the urethra, then it's called urethritis. Urinary infection is never due to the usage of public urinals, it's always internally acquired. Urinary tract infections have become the most frequent infection in humans and are the reason behind multiple presentations to hospital annually. They are typically caused by E.coli bacteria that are found in the colon. The urinary tract infection is the 2nd most frequent infection that you could get. In case you are afflicted by frequent urinary tract infection, then you need to be mindful of it.
There are two urethras in our body and like narrow tubes and about ten inches long. Drain urine into the bladder from each kidney. Bladder, that kind of organ that stores collects urine and stores urine.The Urethra is a small tube, linking the bladder with outer of the body. Now the problem is, any portion of this system can be infected. Urinary tract has severe symptoms, nausea, vomiting, fever are some of them. UTI is common in adults but rare in children. But some time, children get UTI. It's about 1%-2%. In bed wetting, urinary tract infection is the most ordinary urinary tract sickness. In girls and women, this infection problem is common for men younger than 50 years of age. The reason behind this is not well understood but because of a shorter urethra in women might be partially responsible.
Urinary Tract Infection Causes:
UTIs can be challenging or uncomplicated. UTI can happen to anybody, anywhere, anytime. UTIs generally alter the bladder but in some event, the bacterial infection might travel until the kidneys leading to a kidney infection. There are numerous unique causes of UTIs and it's going to be your responsibility to learn about what's going on and the way you can receive the relief that you deserve. They rarely result in disruption of the patient's normal activities. Most UTIs aren't serious, but some can result in serious difficulties, particularly with upper urinary tract infections.
If UTI isn't treated in time, it can lead to chronic kidney ailments." UTIs can happen while pregnant. UTI can be readily treated. UTI is a mixture of both these ailments. Should you be pregnant and think you might have a UTI, make sure to tell your doctor promptly. It is necessary that you get diagnosed and treated whenever possible when you're handling a UTI so you can get relief and save yourself from more severe health difficulties. Whenever you're suffering from UTI you need to increase the consumption of vitamin C containing food items.
Causes Behind This Infection:
When the bacteria get into urine and begin to grow, an infection occurs. At the hole of the urethra where the urine leaves the body, the infection usually starts. Escherichia coli, bacteria are responsible for it.
Wiping and sexual intercourse are the two most common causes. There are also so many reasons those are responsible for infection.
Urinary Tract Infection Symptoms:
Keep your eye on your symptoms and get relief whenever possible in order to don't need to handle this infection longer than necessary. In these cases too an infection can occur. It is among the most frequent infections in local principal care.
The signs and symptoms related to urinary tract infections are frequently very uncomfortable. Since each one of the indicators of a UTI might not be present, it's important to recognize the signs which may be present, particularly for elderly people with dementia. Actually, it's not always critical to have symptoms even you're infected. It can even alleviate signs and symptoms connected with UTI in only about one or two days. In case you have one or more of these symptoms, tell your physician straight away. Seek advice from your physician if any of the aforementioned symptoms appear. There are various symptoms for different sorts of infection.
After the bladder gets inflamed from bacteria, somebody with cystitis is going to have a burning sensation during urination. Refrain from use of alcohol because it will irritate the bladder. The bottom part contains bladder and urethra.
Sometimes, the urine will be slightly pink because of blood. Although he is a waste product produced by our body, it does not contain any bacteria. Regardless of the strong and frequent impulse to urinate, an exact little quantity of urine is passed. The urine ends in the diary will show the way your kid is responding to treatment or whenever they've relapsed. The urine in the bladder is sterile and doesn't contain any micro-organism.
Some, but not all, kinds of bacteria can lead to disease in humans. If left untreated, the bacteria can travel until the kidneys leading to a kidney infection that may be severe. They can cause a UTI. The bacteria will initially travel in the urethra and get to the bladder. Do not use any perfumes close to the genital area which might destroy the helpful bacteria present here.
There are some major symptom below:
** Dysuria: pain at urination.
** Urgency of urine.
** Frequency of urination
** Cloudy urine.
** Bad-smelling urine.
** Bloody urine.
** Nausea.
** Vomiting and so on.
Possibility to Prevent a Urinary Tract Infection:
After bowel movement, women or girls should wipe from front to back so that bacteria can't enter the urethra. After sexual intercourse, empty the bladder regularly. Plenty of fluids should be drunk.
You could save you getting another UTI with the following recommendations:
** Empty your bladder normally as quickly as you sense the want to move; do no longer rush, and make certain you've emptied your bladder completely.
** Wipe from the front to once more.
** Drink plenty of water.
** Pick out showers over baths.
** Live faraway from female hygiene sprays, scented douches and scented tub merchandise. They'll best increase inflammation.
** Cleanse your genital area in advance than sex.
** Urinate after sex to flush away any bacteria that can have entered your urethra.
** In case you use a diaphragm, unduplicated condoms or spermicidal jelly for start manipulate, take into account switching to another method. Diaphragms can boom bacteria growth, even as unduplicated condoms and spermicides can motive infection. All ought to make UTI signs more likely.
** Preserve your genital place dry through manner of wearing cotton panty and unfastened-fitting garments. Keep away from tight denims and nylon panty. They may entice moisture, growing the appropriate surroundings for bacteria boom.
Women face this problem commonly so every woman should aware about this sickness. This article helps to women to care her health. This is for today. Stay with us and enlarge your knowledge level. Be healthy.


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Shall we go through Tuesday's list first? Why not eh? ….
- Cup of tea – DONE. Numerous
- Lunch (use up stuff in the fridge) – NOPE. I won't even dignify where I went for lunch with a namecheck. Suffice to say, I was bad.
- Check out what I have to compress – YEP. Plenty
- Bring in clothes and put them away – YEP. Easy
- Write to a mate – DONE. Compliments are quite easy really.
- Look for anything to take home and dispose of for tomorrow's trip to the tip – DONE. There's nowt to ditch here.
- Go to cinema and watch Guardians of Galaxy (4:30 showing) – DONE. And managed to restrain myself on a large salted popcorn. Guardians of the Galaxy, well – it was OK (quality film reviews available here clearly).
- Go watch St Vincent at Junction – DONE. Interesting – The Junction is the same as it was 15 years ago – dingy, aurally unsatisfying, a static crowd uninterested in actually moving and yet still a great venue. St Vincent was brilliant too. My kinda woman.
Ok so Wednesday was basically sort parents place out day. Managed to:
- Start sorting out garage at home
- Start sorting out other garage
- Ditched an estate full of stuff at Milton tip – old monitors, broken gadgets, generally rubbish.
- Picked up a PS2 controller and memory card whilst there too.
- Went shopping, got some good stuff.
- Got home, watched BB, completed some more levels on Black Ops and went to bed.
- Watched BB USA
- Did a wash
- Cleaned a door
- Went for a motorbike ride
- Lubricated motorbike chain
- Made a decent lunch
- Sorted out films
- Sorted out spinning rust in big laptop
- Chatted to mate
- Played Black Ops
- Found out about a game called 'The last of Us', which I'll get.
- Went to the park and read yesterday's paper.
- Watch BB Usa
- Sort out stuff that's in my old room at parents place so it's clean for DSis/DBil/Dneph
- Perhaps go shopping
- Play black ops
- Contact neglected contact
- Do ccp thing


text: Volume 4.16 | Apr 26 Human Immunology News 4.16 April 26, 2016 In this issue: Publications | Reviews | Science News | Industry News | Policy News | Events | Jobs TOP STORY IL-1 Is a Critical Regulator of Group 2 Innate Lymphoid Cell Function and Plasticity Scientists demonstrated that interleukin (IL)-1β was a critical activator of group 2 innate lymphoid cells, inducing proliferation and cytokine production and regulating the expression of epithelial cytokine receptors. [Nat Immunol] Abstract | Press Release PUBLICATIONS (Ranked by impact factor of the journal) IL-1β, IL-4 and IL-12 Control the Fate of Group 2 Innate Lymphoid Cells in Human Airway Inflammation in the Lungs Investigators report that interleukin 1β (IL-1β) directly activated human group 2 innate lymphoid cells (ILC2s) and that IL-12 induced the conversion of these activated ILC2s into interferon-γ (IFN-γ)-producing ILC1s, which was reversed by IL-4. [Nat Immunol] Abstract Lentiviral Hematopoietic Stem Cell Gene Therapy for X-Linked Severe Combined Immunodeficiency Follow-up data from two older patients demonstrated that lentiviral vector γc transduced autologous hematopoietic stem cell gene therapy after nonmyeloablative busulfan conditioning achieves selective expansion of gene-marked T, NK, and B cells, which is associated with sustained restoration of humoral responses to immunization and clinical improvement at two to three years after treatment. [Sci Transl Med] Abstract | Press Release CD19 CAR-T Cells of Defined CD4+:CD8+ Composition in Adult B Cell ALL Patients Researchers conducted a clinical trial to evaluate CD19 chimeric antigen receptor (CAR)-T cells that were manufactured from defined CD4+ and CD8+ T cell subsets and administered in a defined CD4+:CD8+ composition to adults with B cell acute lymphoblastic leukemia (ALL) after lymphodepletion chemotherapy. [J Clin Invest] Full Article | Press Release Critical Role of CD2 Co-Stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans Assessment of natural killer (NK) cell repertoires in 60 NKG2C−/− donors revealed a broad range of NK cell populations displaying characteristic footprints of adaptive NK cells, including a terminally differentiated phenotype, functional reprogramming, and epigenetic remodeling of the interferon-γ promoter. [Cell Rep] Full Article | Graphical Abstract Immunomodulation by Mesenchymal Stem Cells in Treating Human Autoimmune Disease-Associated Lung Fibrosis The authors aimed to define the immunopathology involved in pulmonary exacerbation during autoimmunity and to determine the potential of mesenchymal stem cells (MSCs) in correcting these disorders. T cell subsets involved in the process of connective tissue diseases (CTD-IP) were defined, while the regulatory functions of MSCs isolated from the bone marrow of normal individuals on cytotoxic T cells and CTD-UIP human primary lung fibroblasts were investigated in vitro. [Stem Cell Res Ther] Full Article Characterization of the Immunomodulatory Effects of Meningococcal Opa Proteins on Human Peripheral Blood Mononuclear Cells and CD4+ T Cells Researchers investigated the effects of various Opa+ and Opa– antigens from Neisseria meningitidis strain H44/76 in a range of in vitro conditions using peripheral blood mononuclear cells and purified CD4+ T cells, measuring T cell proliferation by CFSE dilution using flow cytometry. [PLoS One] Full Article TNF Is a Key Cytokine Mediating Neutrophil Cytotoxic Activity in Breast Cancer Patients Scientists assessed the cytotoxicity of neutrophils from 90 newly diagnosed breast cancer patients, 24 ductal carcinoma in situ patients, 56 metastatic breast cancer patients, and 64 women with no history of cancer. They report that neutrophils from metastatic and newly diagnosed breast cancer patients are significantly more cytotoxic than neutrophils from cancer-free individuals. [npj Breast Cancer] Full Article PD-1 Marks Dysfunctional Regulatory T Cells in Malignant Gliomas In both patients with glioblastoma multiforme and healthy subjects, circulating programmed cell death protein 1 (PD-1)hi Tregs displayed reduced suppression of CD4+ effector T cells, production of IFN-γ, and molecular signatures of exhaustion. [JCI Insight] Full Article | Press Release 1 | Press Release 2 Subscribe to our sister publications: Immunology of Infectious Disease News & Immune Regulation News! REVIEWS T Cell Responses to Cytomegalovirus The authors discuss the molecular triggers that promote memory inflation, the idea that memory inflation could be considered a natural pathway of T cell maturation that could be harnessed in vaccination, and the broader implications of cytomegalovirus infection and the T cell responses it elicits. [Nat Rev Immunol] Abstract Trained Immunity: A Program of Innate Immune Memory in Health and Disease The discovery of trained immunity may open the door for novel vaccine approaches, new therapeutic strategies for the treatment of immune deficiency states, and modulation of exaggerated inflammation in autoinflammatory diseases. [Science] Abstract Toxicity and Management in CAR T-Cell Therapy Abrogating toxicity has become a critical step in the successful application of chimeric antigen receptor (CAR) T cell technology. To this end, investigators review the reported and theoretical toxicities of CAR T cells and their management. [Mol Ther Oncolytics] Abstract Visit our reviews page to see a complete list of reviews in the human immunology research field. SCIENCE NEWS Phase II Cervical Cancer Study with Advaxis' Axalimogene Filolisbac Selected for Poster Discussion Session The poster, "ADXS11-001 immunotherapy in squamous or non-squamous persistent/recurrent metastatic cervical cancer: Results from stage I of the Phase II GOG/NRG0265 study," was selected as one of 12 abstracts to be featured. [Press release from Advaxis, Inc. discussing research to be presented at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting, Chicago] Press Release First Presentation of Overall Survival Data for Opdivo® (Nivolumab) Shows Significant Survival Benefit at One-Year versus Investigator's Choice in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Bristol-Myers Squibb Company announced the first presentation of data from CheckMate -141, a Phase III open-label, randomized trial, evaluating Opdivo in patients with recurrent or metastatic squamous cell carcinoma of the head and neck after platinum therapy compared to investigator's choice of therapy. [Press release from Bristol-Myers Squibb Company discussing research presented at the 2016 American Association for Cancer Research (AACR) Annual Meeting, New Orleans] Press Release Late Breaking Data from Advaxis Phase II Study of AXAL Highlights Potential of the Company's Lm Technology™ Platform Advaxis, Inc. announced immunological and pathologic data from the company's ongoing Phase II study of its lead immunotherapy candidate, axalimogene filolisbac (AXAL), in patients with late-stage HPV-associated oropharyngeal cancer. [Press release from Advaxis, Inc. discussing research presented at the 2016 American Association for Cancer Research (AACR) Annual Meeting, New Orleans] Press Release Studies Show Continued Promise for Immunotherapy Drugs Several new immunotherapy drugs are continuing to show benefits across a range of cancer types, according to a slew of new data. The new results confirm their benefit for some melanoma patients, and also suggested they can help certain patients with head and neck cancers, and those with Merkel cell carcinoma. [Press release from Cancer Research UK discussing research presented at the 2016 American Association for Cancer Research (AACR) Annual Meeting, New Orleans] Press Release Clinical Data from IIT Using Medigene's Dendritic Cell (DC) Vaccines in Prostate Cancer Presented Medigene AG announced that clinical data of a DC vaccine trial for the treatment of prostate cancer were presented. [Press release from Medigene AG discussing research presented at the 2016 American Association for Cancer Research (AACR) Annual Meeting, New Orleans] Press Release Immunotherapy Is First to Show Survival Benefit in Head and Neck Cancer The immunotherapy drug nivolumab has become the first to show a survival benefit in head and neck cancer, after a major international trial found that it was more effective than standard chemotherapy. [Press release from The Institute of Cancer Research discussing research presented at the 2016 American Association for Cancer Research (AACR) Annual Meeting, New Orleans] Press Release Biothera Pharmaceuticals Presents New Cancer Immunotherapy Research Biothera Pharmaceuticals, Inc. announced research providing new insights into the ability of the company's Phase II cancer immunotherapy to coordinate innate and adaptive immune responses and enhance the effectiveness of combination therapies. [Press release from Biothera Pharmaceuticals, Inc. discussing research presented at the 2016 American Association for Cancer Research (AACR) Annual Meeting, New Orleans] Press Release Jounce Therapeutics Presents Data Highlighting Advances from Two Programs in Its Immuno-Oncology Pipeline Jounce Therapeutics, Inc. presented new preclinical data from two programs in the company's immuno-oncology pipeline. Jounce's first presentation highlighted JTX-2011, a humanized ICOS (inducible co-stimulator molecule) agonist antibody being developed for the treatment of solid tumors. [Press release from Jounce Therapeutics, Inc. discussing research presented at the 2016 American Association for Cancer Research (AACR) Annual Meeting, New Orleans] Press Release From our sponsor: Working with blood? Download the immune cell frequencies app. INDUSTRY NEWS AstraZeneca Beefs Up Immuno-Oncology Pipeline with TapImmune Technology AstraZeneca has placed its bets on a cancer vaccine technology from TapImmune. A joint AstraZeneca-TapImmune Phase II ovarian cancer trial will start this quarter at the Sloan Kettering Institute. [TapImmune, Inc.] Press Release TxCell and Ospedale San Raffaele Launch Collaboration for the Development of CAR-Tregs in Lupus Nephritis TxCell SA and Ospedale San Raffaele announced they have entered into a strategic R&D collaboration. The collaboration will include a development arm focused on lupus nephritis, as well as a research program dedicated to chimeric-antigen-receptor engineered regulatory T (CAR-Treg) biology. [TxCell SA] Press Release OncBioMune Enters Joint Venture, Preparation for Phase II Trial of Novel Cancer Vaccine for Prostate Cancer Underway OncBioMune Pharmaceuticals, Inc. announced the execution of the contract to form a joint venture with Vitel Laboratorios S.A. de C.V. for the purpose of developing and commercializing OncBioMune's portfolio of innovative cancer therapies in Mexico and Latin America. [OncBioMune Pharmaceuticals, Inc.] Press Release Bristol-Myers Squibb's Opdivo® (Nivolumab) Receives Breakthrough Therapy Designation from U.S. Food and Drug Administration for Previously Treated Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Bristol-Myers Squibb Company announced that the U.S. Food and Drug Administration has granted Breakthrough Therapy Designation to Opdivo for the potential indication of recurrent or metastatic squamous cell carcinoma of the head and neck after platinum based therapy. [Bristol-Myers Squibb Company] Press Release POLICY NEWS Researchers Push for Personalized Tumor Vaccines It is precision medicine taken to the extreme: cancer-fighting vaccines that are custom designed for each patient according to the mutations in their individual tumors. With early clinical trials showing promise, that extreme could one day become commonplace — but only if drug developers can scale up and speed up the production of their tailored medicines. [Nature News] Editorial National Institutes of Health (United States) Food and Drug Administration (United States) Center for Biologics Evaluation and Research (United States) European Medicines Agency (European Union) Medicines and Healthcare Products Regulatory Agency (United Kingdom) Therapeutic Goods Administration (Australia) EVENTS NEW Innate Immunity in Host-Pathogen Interactions June 26-29, 2016Heidelberg, Germany Visit our events page to see a complete list of events in the human immunology community. JOB OPPORTUNITIES NEW Research Technologist – T Cell Immunology (STEMCELL Technologies Inc.) NEW Research Technologist – Cell Separation (STEMCELL Technologies Inc.) Scientist – Bioengineering (STEMCELL Technologies Inc.) Senior Scientist – Immunology and Cell Separation (STEMCELL Technologies Inc.) Postdoctoral Position – Immunology (Erasmus MC) Faculty Positions – Microbiology and Immunology (National University of Singapore) Engineering Project Lead (Cytonome) Postdoctoral Fellow – Immunology (University of Wisconsin – Madison) Postdoctoral Position or Research Scientist – Mucosal Immunology (Qu Biologics) Postdoctoral Fellow – Immunology (Ragon Institute of MGH, MIT and Harvard) Postdoctoral Researchers – Tumor Immunology and Cancer Immunotherapy (University of California, Los Angeles) Recruit Top Talent: Reach potential candidates by posting your organization's career opportunities on the Connexon Creative Job Board at no cost. Have we missed an important article or publication in Human Immunology News? Click here to submit!Comments or suggestions? Submit your feedback here Learn more about Human Immunology News: Archives | Events | Contact Us


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A teachable moment is an unplanned learning opportunity for someone to acquire a new skill or new behavior, or a new way of expressing and coping with an emotion.
Yep, we had one of those in the bakery yesterday.
The bakery is blessed with some very talented decorators who love to create. I encourage and empower them but they sometimes make commitments that are not in the bakery's best economic interests.
The relationship between the cost of decorating time and the price of a cake is a difficult one to fully grasp. Hence today's teachable moment.
It began about a week ago when a lady called asking if we could make a "wrestling cake."
We've made wrestling rings before and they are pretty straight-forward. Knowing this, the decorator quoted a price for a simple square cake. Which would have been fine if it stopped there.
But no.
The customer wanted more, so she also agreed to create a wrestler to put in the ring. At no additional cost. By hand, out of gum paste. For the uninitiated, that's about an hour's work, just for the figure (lots of small details in several colors of gum paste). We've been making a lot of fondant figures lately, elephants and dogs and cats and people, but they go on larger stacked or carved cakes where the costs of such details are included in the price of the cake. I was a bit concerned the price of the cake would not cover the time needed make the figure, but was assured it would be easy. Okaaaay (I'm trying to delegate more and be less of a control freak).
A couple of days ago, as we were preparing for Rosie's party, we discovered we were low on gum paste. The wrestler (standing up) could not be made from fondant because it's not strong enough, and we didn't have time to order more.
So she called the customer and explained we couldn't make the wrestling figure from gum paste, offering to buy an action toy instead. The customer said OK.
The small square cake was decorated with a hand painted fondant mat, cushioned sides, poles, ropes and a $10 action figure she bought and donated to the cause.
The customer came in to pick it up and the decorator brought out the cake, commenting that it turned out really nice.
The customer replied "not nearly as nice as it would have been with the gum paste wrestler."
She was crushed, having gone above and beyond to try to deliver her promised cake. You can't blame the customer for asking for as much as possible. It's also not the customer's fault we were out of gum paste. It was a lose-lose for all involved. As soon as the customer left, I seized upon the teachable moment, which included managing unreasonable expectations, covering the cost of time-consuming details on small cakes, and inventory management.
Hopefully, the next time someone requests a small cake with 3-d animals or figures, they'll be offered manageable options.


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To replace rotten frames and sills is an expensive business, so keeping them clean is important in the long run!
Try us out, contact Window Cleaning Swindon
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MANILA -- The Chinese government needs to implement a green taxation system to attain its target of reducing pollution and promote sustainable economic growth, the Asian Development Bank said Wednesday.
In "Toward an Environmentally Sustainable Future," ADB's latest report on Chinese environment, ADB analysts recommended that Chinese policymakers impose taxes on resource extraction and pollutant and carbon dioxide emissions.
ADB analysts also suggest that China can offer tax cuts to companies to offset investments in pollution control equipment, raise resource rent taxes, and taxes on luxury goods and "one- time consumer goods."
The Manila-based lender said such fiscal incentives are crucial given that rapid economic growth in China has also resulted to several environmental problems including water and air pollution and increased volume of solid waste.
"While China's environment has improved in many respects, the overall situation continues to deteriorate as environmental pressures increase," Robert Wihtol, Director General of ADB's East Asia Department said in a statement.
The ADB noted the progress that China has made in the past five years to reduce pollution and manage its solid waste problem. China'sd investment on environmental infrastructure, its focus on achievable targets, and strengthened accountability and enforcement has reduced chemical oxygen demand and sulfur dioxide emissions by 10 percent. Energy consumption per unit of GDP was cut by nearly 20 percent albeit robust growth.
The Chinese government has also made major advances in the control of industrial and domestic point sources of water pollution.
That said, the ADB noted that water and air pollution remain a problem.
Pollution from runoff of fertilizer, pesticides, and discharges from intensive animal production facilities pollute the country's water supply. Seven of China's biggest cities are among the 10 most polluted cities in the world, mostly due to vehicle emissions.
Industrial solid waste management is also a challenge.
The ADB urges the Chinese government to change an " unsustainable growth pattern."
Aside from implementing a green taxation system, the ADB is encouraging the government to invest in natural resources. It is also calling for the formation of a national regulatory framework of "eco-compensation," an initiative where the government or private sector pays for ecological services protection by households, communities, or local governments.


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Marriage beckons us with the hope of enduring love, close companionship and ultimate union. In truth, marriage and child rearing are probably the most difficult and rewarding ventures one can take up in a lifetime.
The marriage journey begins with an experience of love that will "right all wrongs" and "conquer every darkness." It is this work of marriage that few of us are ever prepared for and even fewer are equipped to undertake. Marriage will challenge the hardiest of souls. Marriage enfolds two storylines with the accompanying strengths, challenges, fears, insecurities, doubts and dreams of each person. And it is here in the intimacy of marriage where those two stories unfold, intertwine and get worked out into a new story to be told.
A story wouldn't be a story if it didn't have challenges and difficulties. Whether your issue is infidelity, addiction, betrayal, bad boundaries, poor communication or other traumas, marriage therapy works with couples to recognize and resolve conflicts, increase healthy communication, establish healthy boundaries, heal hurts and wounds and plot a course for the future. The future is yours to write. We can help you consider how that story might unfold.
We provide a safe, warm, caring, confidential environment to tell your story. It is here that it can be rewritten.


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A new, 13-week session of GriefShare recovery groups will start on Monday, September 16th. GriefShare is a recovery group for those mourning the death of a family member or friend. We understand that there are other losses in life that create feelings of grief. You might be experiencing a job loss, a divorce, estrangement from a child, or the loss of friends because of a move. This grief is real, but it is not the kind of grief discussed in GriefShare sessions. GriefShare groups meet weekly for 13-week sessions to help you face these challenges and move toward rebuilding your life.
GriefShare is free to attend and you can start coming at any time in a recovery group cycle. For any questions you have, please contact our facilitator, Libby Nunn, directly.


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|twiggy wearing yves st. laurent
in a way, it's strange that i haven't paid more attention to ysl, because yves saint laurent the man is a character who fascinates me. promoted to the position of head designer at dior at age 21, succeeding the man himself (who had hand-picked him before his own untimely death), he saved the company from bankruptcy with his 1958 spring collection. by fall of that same year, he was old news and in 1960, the house of dior colluded with the french government to see him conscripted to the army so that they could replace him. (he later sued them and won his case.)
|androgyny rocks
on a more personal note, one of my prized shoe possessions (found at well less than their value on ebay) is a pair of boots from designer tom ford's final season with the fashion house that are really more like a piece of wearable art than something you'd find at payless.
i may never get to own a piece of vintage ysl couture (the house closed in 2008, although its parent company, gucci, continues to produce ready-to-wear lines as well as accessories and cosmetics, under the ysl banner.), but i can indulge a little in the colour offerings found at their counters at the bay and holt renfrew. here's a few choice morsels:
|mondrian, not mascara
so far, my all-time favourite mascara has been benefit's bad gal, but i'm always on the lookout for something new. with faux cils, i may have found it. it does indeed add volume, so that you have a lovely fringe without a lot of fussing around or dealing with multiple coats. at first, i thought it was clumping a little, but an extra pass with the wand combed that right out. it doesn't deposit any unsightly lumps and, although the applicator can get a little messy when first removed, it doesn't go on messy like some other volume formulas i've tried. best of all, i find that the wand separates the lashes enough that, despite the considerable enhancement it gives, lashes never look "heavy". i was easily able to apply it to my bottom lashes without making my eyes look all squinty.
as far as the "noir radical" colour is concerned, i took it for a marketing ploy. black is black, right? well, not quite. i tried it next to mac's "false lashes" mascara, which is another formula i really like and, yes, i could easily see a difference. the "faux cils" was noticeably darker. i think that the intense black colour augments the appearance of volume as well, since it really makes lashes pop.
a definite winner! ($36cad)
rouge pur couture :: rouge saadi :: everyone seems to flip over ysl's "rouge volupté" lipsticks, their moisturising intense colour line. personally, while i really liked the formula at first, i've grown a little disenchanted with it. i find it very slippery and, on me at least, it wears off very quickly and leaves me with the lipstick "ring of shame". couple that with the fact that they smell strongly of watermelon (i hate watermelon) and i'm not exactly rushing back to try more.
|rouge saadi #3
the "rouge pur couture" colours were launched this spring and are a different formula from the original "rouge pur" lipsticks. this series of shades are inspired by the designers original palette of bold colours- red, orange and magenta shades. if you like bold lips (and i do), the colour selection is dazzling. the nice thing is that they are pretty true to the colour you see in the tube, which most lipsticks aren't. there are a few more understated colours available, but this whole collection seems to be about the brights. the reds in particular are just ravishing.
|noir lacque #18
for those who prefer their colours more toned down, the rouge pur couture line includes two shades- a shimmery, semi-sheer white and an intense purplish black-brown- which can be used to lighten or deepen other colours. of course, if you're like me, you'll just as soon where the dark colour- noir lacque (#18)- on its own. and there's no rule saying you can't do that...
you can see a full and very accurate set of pictures of the rouge pur couture line here. ($37cad)
|slate green #5
slate green doesn't remind me much of a slate colour at all, really. it's a very cool green- i'd say more like a slightly lightened forest green, with a gorgeous sea blue shimmer. unfortunately, while the shimmer shows both in the pan and when i swatched it on my finger, i couldn't get it to show up in use. granted, i could have built the shadow up more, but given how well the colour went on and how much payoff it gave, it seemed pointless to keep packing stuff on my eyes.
|slate green #5
the shadow came with a little brush and sponge applicator, which i didn't end up using, but which would be great for travel.
once again, you can see a complete set of product swatches via karla sugar's site (shadows are second from the top). the colours surprise me a little, in that they're so far off what a "regular" range would be. there aren't really any "basics" (beige, cream, etc.) and the bulk of the colours are either fairly dark or quite bright. for my part, i'm quite happy with the selection. for me, these shadows are more of a "special" purchase, so i'd rather have them in colours that would be a feature. i can get light neutrals anywhere. ($34cad)
i have to say that my one beef with ysl is their packaging. everything is made to look like a little jewel case, with gilt and filigree, like something that immediately announces "high end". but for some reason, they insist on making these lovely little packages out of a cheap plastic that scratches and smudges so easily that even bringing them home can leave them looking shabby. this holds true for all the products i've tried from them, although i will say i found the mascara a little better. for the price range they're playing in, it's not something they can really afford to continue with. chanel has a lock on black chic, shu uemura always looks nicely futuristic, mac cosmetics at half the price have a streamlined and immediately recognisable look with their gunmetal casing (and "bullet" lipsticks). for the money they charge, they could look a lot better.
in closing, here's a look that i did that incorporates the three products (only one colour of lipstick) reviewed here, so you can see them "in action". i think it shows pretty well how well and precisely and evenly the shadow and lipstick apply, with no extra effort required.
products used
face ::
nars sheer glow foundation mont blanc
mac prolongwear concealer nw20
eyes ::
mac vex e/s [soft grey-green with pink sheen: absolutely necessary; accept no substitutes]
mac motif e/s [peachy-gold with pink sheen]
nars night star [light peach with gold shimmer]
ysl slate green e/s [deep blue-toned green]
mac greasepaint stick greengrease [black-green, used as a liner]
ysl faux cils mascara noir radical
cheeks ::
mac magically cool liquid powder truth & light
mac my highland honey blush
lips ::
ysl rouge pur couture rouge saadi
|tom ford for yves st. laurent made, evidently, with me in mind


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Mexican chilli
The thing I love about Mexican food is the flavour complexity. I love the way each ingredient hits your taste buds and performs its own stunning one man show before pairing up with its buddies and banding together to put on a performance that blows you away. Corny analogy I know, but I'm better on the pots and pans than I am on the keyboard. Either way though, this is a darn good chilli and I hope it fires up as much passion in you as it did me.
700g lean beef mince
1 large onion, finely diced
1 large carrot, grated
1 large red pepper, diced
3 cloves garlic, minced
1 tbsp olive oil
3 tsp hot chilli powder
2 tsp cayenne pepper
1 tbsp smoked paprika
1 tbsp tomato puree
1 tin kidney beans, rinsed and drained
2 tins chopped tomatoes
600ml water
Large handful of fresh coriander, chopped
To serve
Freshly steamed or boiled white rice
Sour cream
Cheddar cheese, grated
Heat the olive oil in a large frying pan or cooking pot. Add in the beef mince and cook for 5-6 minutes until the mince in browned all over. Now add in the chopped onion, grated carrot, diced red peppers and garlic before cooking for another 5 minutes. Add in the chilli powder, cayenne pepper, smoked paprika and tomato puree, stir well to combine and cook for another couple of minutes. Now add in the kidney beans and chopped tomatoes before topping up with the water. Mix well, cover with a lid and leave to simmer away on a medium heat 60 minutes. To serve, remove from the heat and stir in the chopped coriander before spooning over some fluffy white rice and topping with a small dollop each of sour cream, guacamole and finally grating over some lovely cheddar cheese.
Serves 6
1 Comment
Well the cool days of fall have definitely arrived here in Nashville Tennessee so this chili recipe looks just perfect for dinner. Well done.


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The importance of knowledge, to make money in the stock market, is a well accepted fact. At Roongta Rising Group, we focus more on importance of ATTITUDE. It is only with the right attitude that one can apply the knowledge and skill for rewarding objective. We feel that it is our attitude and the guts to act on our knowledge that creates wealth for our investors.
It is our attitude to be different and create the difference. For years, the intelligent investors are talking about the merits of 'long term' investment and the 'buy and hold' philosophy. We beg to differ. Our research shows there is enough power in 'short term trading' too. And it is our attitude that has given us guts to exhibit the same for years. Yes, this attitude of ours to execute our beliefs, even if it is different from the conventional wisdom, has helped our investors creating wealth. We call it a winning attitude.
With this winning attitude, Roongta Rising Group has entered the Capital market. Our intraday trading ability and short term money making track record is not only extra ordinary but it is unparalleled one.
Our Chief promoter Mr. Anil Roongta himself is a trader par excellent. It is because of his sharp acumen along with the details worked out by the research team that none of the market movements escapes our attention. While many analysts just observe such movements, we actually take advantage of the same.


text: New Hyde Park, New Hyde Park, New York, United States is a New Hyde Park luxury Single Family Home listed for sale 649,000 USD. This high end New Hyde Park Single Family Home is comprised of 3 bedrooms and 1 baths. Find more luxury properties in New Hyde Park or search for luxury properties for sale in New Hyde Park.


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Deep SpaceTeleport to an abandoned starship in this sci-fi adventure
Book It Now " target="_blank">Book It Now ?>
The Story
After no contact for years, there's been a distress signal from the abandoned starship, Nebulous! You have just 30 minutes to teleport aboard the craft, figure out what happened and get back safely. But be prepared to battle an asteroid storm, rewire the engines, refuel the power supply and stop an evil Artificial Intelligence in time to save the world!
- Special Events
- Portable Game (Pop-up)
- Friends & Family
- Team Building
- Dating
- Students
- Gamers
- Tourists
- Kids and Family
- Advanced
- Credit Card
- Cash
- Online
Difficulty Level5
More Information
Number of Players:
2 to 12
Room Accepted Currency:
Minimum Age:
Minimum Age With Adults:
Game Duration in Minutes:
Opened On:
April 2015
GuReview - Deep Space
by Gureviewer: rachelklepadlo
Ease Of Booking :
There are no reservations at this location - it is first come, first serve. We called ahead to find out when the birthday parties were that day, and arrived 2 hours prior in order to play the 2 games we wanted to play. These are public, mixed group adventures.
Entrance Rating:
Lobby : The lobby had props, t-shirts, and random items for sale. There is no available seating. Upon entry to the venue, you notice the three doors 'leading to each adventure' as well as a token box next to the door. Upon entry, you purchase the tokens for the adventures you wish to play, and stand by the door for the next adventure to begin.
Hospitality : The restrooms are clean and located deep within the 5 wits location. There are no refreshments for sale, but there are dozens of places to eat within the mall.
Time Keeping : Games begin every 10-15 minutes. We only waited a few minutes for the next game to begin.
Briefing Details : After no contact for years, there's been a distress signal from the abandoned starship, Nebulous! You have just 30 minutes to teleport aboard the craft, figure out what happened and get back safely.
Operator Intro : Exciting - takes you into the story
Operators :
Pleasant, professional, and kept everyone going. Very accommodating to allowing us a private experience.
The Game :
One of the best space themed adventure escape rooms I have ever played. Immersive, challenging, and still kid-appropriate. Half star removed due to the game having a 12 player max, but only enough puzzles to keep a group half as large entertained.
The Venue :
I am excited to see how they build out additional rooms at this location. The venue is clean, the games are fun, and it will be something to do that is not your standard 'lock and combo' escape room. This game is definitely geared towards those looking for a full on adventure.
Main Room - First Glance :
We were loaded into a 'teleporter' to bring us to our ship. I cannot go into further details than this without giving the game away!
Flow :
Excellent flow - flawless and coherent
This game has an obvious game flow - complete a task or two in order to gain entry to the following room. As the game is 30 minutes, it is expected that each area will take about 10 minutes to get through.
Puzzles :
Well thought of. Intriguing
Wow! These were never before seen, high tech puzzles! It was one of the best set designs I have ever experienced, and it made me super excited to complete each room and see what was in store! Most of the puzzles were doable by children (this game is geared towards age 10-14, if I had to guess).
Hints & Clues : No clues given
Policy: Loose or no policy
Hints & Clues Quality: No hints
Quality: OK
Closure & Debrief :
Excellent (Catharsis)
With our team of 4 experienced enthusiasts, we completed our mission in 32 minutes with a score of 90 (out of 100). This room has enough going on to keep a group of 4-6 individuals (or a family) truly engaged for the entire mission. Maximum team size is 12 people, but there is not enough to do for 12 people.


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LEWISTON, Maine — The state of Maine may have a difficult time recovering any of the more than $500,000 it already paid a private consultant to develop a study and analysis of Maine's welfare system following the revelation that parts of the study contained plagiarized material, a Maine law professor said Wednesday.
At the same time, federal investigators plan to review the state's contract with the Alexander Group to determine if the federal funds used to pay the consultant were used appropriately.
Gov. Paul LePage said the state stopped paying Rhode Island-based welfare consultant Gary Alexander, and his administration may ask Alexander to refund the state's money for the work his firm was contracted to do.
In September 2013, the LePage administration authorized a $925,200 no-bid contract to a group headed by Alexander, the former public welfare director for Pennsylvania and Rhode Island, on the basis Alexander was "uniquely qualified" to do the work.
Under Maine law, state agencies can issue no-bid contracts when the vendor doing the work has a unique capability or experience to do work no other entity is capable of doing.
On Wednesday, Gerry Petruccelli, a University of Maine Law School professor who specializes in contract law, said the language in the contract between Alexander and the state was "fuzzy" enough that the state may have little legal recourse.
Stopping any additional payments and terminating the state's contract with Alexander may be the state's best option, he said.
"The language defining what he was supposed to do was not particularly tidy," Petruccelli said of the contract with Alexander.
But the state's ability to legally demand a refund would depend on whether it could show the work provided by Alexander and his consulting firm was essentially without value, Petruccelli said.
The plagiarism issues with the report may be a basis for arguing the Alexander Group did not do what it said it would do, he said.
Petruccelli is a Democrat but said he based his opinion that the state's position is problematic on his legal studies, not his political affiliation.
Under the contract, the Alexander Group was paid monthly installments with additional payments being made after specific portions of the study were delivered to the state, but the contract allowed the state to withhold up to 40 percent of those additional payments until it was satisfied with the work turned in.
The contract was also amended in April to give the Alexander Group an additional two months to complete the final portions of its report, pushing a May 15 target due date to July 15.
The contract was administered by Maine's Department of Health and Human Services but was authorized by LePage's office.
The Alexander Group delivered its second installment of the study earlier this month. But despite the consultant meeting the due date of May 15, it was soon discovered large portions of the report had been lifted from previously published studies conducted by organizations other than the Alexander Group.
Alexander acknowledged problems with the report, noting the consulting firm would resubmit the report to correct what he characterized as attribution errors.
"Specifically a failure to ensure intended footnotes were included," Alexander wrote. "We regret the error and offer our sincere apologies. Such usage is never acceptable, and appropriate checks are being put in place to ensure that this unfortunate outcome is never repeated."
LePage, who in January refused to make public the first installment of the report — after it was delivered days past its "target" date of Dec. 1, 2013 — has since said he's looking into recovering some of the payments already made.
John Martins, a spokesman for DHHS, confirmed Wednesday that half of the $501,760 — or $249,185 — already paid to Alexander was federal funds.
At the federal level, officials with the Centers for Medicare and Medicaid Services in Boston referred all questions on the use of federal funds to pay Alexander to the Office of the Inspector General.
Phil Coyne, Assistant Special Agent in Charge of the federal OIG, HHS regional office in Boston, said investigators would be reviewing the state's contract with the Alexander Group to determine if the federal funds used to pay the consultant were used appropriately.
Tim Feeley, a spokesman for Maine Attorney General Janet Mills, said Wednesday that Mills' office did not assist the administration in drafting the contract and had not been asked for advice on how to proceed but was standing by to assist the governor's office upon request.
Meanwhile, Democratic leaders in the Legislature sent a letter to LePage Wednesday asking him to spell out the state's legal options.
Co-signed by House Speaker Mark Eves, D-North Berwick, and Senate President Justin Alfond, D-Portland, the letter also reiterates concerns the contract should have had greater public scrutiny prior to being inked.
"From day one, the Alexander contract has been highly questionable. The no-bid contract received no public review, no opportunity for legislative oversight and no adequate vetting of this contractor. Worse, it used federal funds intended to help struggling families and hungry children," Eves and Alfond wrote in part.
LePage spokeswoman Adrienne Bennett said in a written statement Wednesday afternoon Eves and Alfond were trying to politicize the issue just days in advance of the Democratic State Convention.
"President Alfond and Speaker Eves are a week late to the party. … The governor will not allow politics to interfere with getting to the bottom of these allegations," Bennett wrote. "As the governor has stated previously, he immediately suspended payment one week ago. Proper follow-up is being conducted, looking into the validity of these accusations, and appropriate action will be taken, including and up to termination of the contract, if warranted."
Senate Minority Leader Mike Thibodeau, R-Winterport, also issued a statement Wednesday saying he had reached out to LePage's office and had been "reassured they are taking these allegations very seriously, are taking appropriate steps to look into their validity and considering the appropriate course of action going forward."
House Minority Leader Ken Fredette, R-Newport, on Wednesday urged Democrats to show "some patience in terms of letting the chief executive deal with evaluating the report in light of the contract and make a determination as to what his course of action is going to be."
BDN State House Bureau Chief Christopher Cousins contributed to this report.