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Joe has over 30 years experience in the life sciences industry with a successful track record of generating investment returns. He was a partner at Abingworth LLP for 12 years, where he led venture-capital style investments in public companies. He has founded and managed public equities funds and been a director of Algeta (acquired by Bayer AG for $2.9 billion), Amarin plc, Cytos (merged with Kuros) and Epigenomics AG, and is currently a director of Autolus Therapeutics plc, which recently listed on the Nasdaq.
Joe began his career at the Ciba (now Novartis) Foundation, before joining The Wellcome Trust in 1990 where he became head of the strategy team. He then moved to the City of London as a pharmaceuticals analyst at Dresdner Kleinwort Benson before being appointed as Head of Global Healthcare and Portfolio Manager at First State Investments, Commonwealth Bank of Australia, in London. Joe has a PhD in Biochemistry and extensive board level experience of building successful life science companies.
Jonathan specialises in biotechnology investments. He currently sits on the board of Artios Pharma, Atox Bio, Mitoconix Bio and Arix's New SeedCo. Prior to joining Arix Bioscience, Jonathan spent five years at Touchstone Innovations (formerly Imperial Innovations), where he was a Principal in the Healthcare Ventures team. He was involved with the formation and investment in a number of early stage companies. Jonathan also worked at MRC Technology, sourcing and evaluating new small molecule and antibody drug discovery projects.
He has a first-class degree in biology from the University of Oxford, a PhD in Molecular Medicine from UCL, carried out postdoctoral research at the Cancer Research UK London Research Institute (now Crick Institute), and published research in journals including PNAS, New England Journal of Medicine, and Nature Genetics. Jonathan also has an MBA with distinction from Imperial College, and is a Trustee of the Autism Research Trust.
Mark has over ten years of experience in the life sciences industry. He was previously a principal at Longitude Capital, where he focused on investments in both private and public biotechnology and medical technology companies. Prior to Longitude, he was a consultant at the Boston Consulting Group, where he was responsible for strategy and corporate development projects for pharmaceutical and biotechnology companies. Before BCG, Mark worked in corporate development at Gilead Sciences and market planning at Genentech. Mark has an MBA from The Wharton School at the University of Pennsylvania, an MS in Biotechnology from the University of Pennsylvania, and a BS in Management Science from the University of California at San Diego.
Christian has over 20 years experience in the life science industry. Prior to joining Arix Bioscience he was for four years CEO of Rigontec GmbH, a German Biotech start-up company in the immune oncology space. Christian led Rigontec to a successful acquisition mid 2017 by MSD valuing EUR 115 MM in upfront payment and additional EUR 349 MM in potential milestones. Between 2008 and 2014 Christian was President and CEO of Neovii Biotech, previously Fresenius Biotech. During his tenure one antibody product was brought to market and the indication for another product expanded. Christian was instrumental in selling Fresenius Biotech to the Neopharm Group, Israel, to form Neovii Biotech and positioning it as a successful stand-alone business. Before joining Fresenius, Christian was Senior Vice President, European Operations of Coley Pharmaceutical Group, Inc, a pioneer in the development of immunostimulatory oligonucleotides, and served as Managing Director of Coley GmbH. He was part of the leadership team which built Coley Pharmaceuticals from inception through multiple financing rounds, a NASDAQ IPO and, following a number of significant pharma deals, to a trade sale to Pfizer in 2007.
Before entering the life science industry Christian was successfully performing academic research at the Max Planck Institute in Martinsried, Germany. He received his undergraduate degree and PhD from the University of Cologne and did postdoctoral research in oncology and virology at the Scripps Research Institute in La Jolla, California.
Before joining Arix Bioscience at its inception, Ed spent 18 years as an equity analyst and Portfolio Manager in Europe and Australia. From 2004 to 2014, he was Head of Research at Alliance Bernstein and then a senior portfolio manager at AMP Capital, a leading Australian investment house with over A$130bn in funds under management, both in Sydney, Australia. At AMP Capital, he managed the growth equity portfolios and launched a small companies fund. As part of his responsibilities he focused on the Healthcare sector.
Prior to his move to Australia, Ed analysed European equities at UBS Asset Management and JP Morgan Investment Management. He gained an MA in Chemistry and MSc in Management at the University of Oxford and is a Chartered Financial Analyst.
Daniel has over ten years of experience in healthcare. Daniel joined Arix Bioscience from OrbiMed Advisors, where he played key roles across investments in both biotherapeutics and medical devices. Investments he has supported include CardiAQ (acquired by Edwards), Civitas Therapeutics (acquired by Acorda), Relypsa (acquired by Galenica), Cynapsus (acquired by Sunovion), as well as other public and private companies. Prior to OrbiMed, Daniel was the Associate Director of Cardiovascular Research at Arisaph Pharmaceuticals where he was responsible for pre-IND discovery and development for programmes in lipid modulation. He received his MD and PhD in Biochemistry from Tufts University School of Medicine, and has undergraduate degrees in Mathematics and Chemistry from MIT.
John Cassidy joined Arix Bioscience in February 2018. John previously worked at L.E.K. Consulting LLP, as a Senior Life Science Specialist, responsible for strategy and transaction support for pharma, biotech and private equity clients. John has a first-class degree in Biochemistry from Imperial College London, a PhD in Neuroscience from University College London and has published research in journals including PNAS Proceedings of the National Academy of Sciences, Nature Communications and Journal of Neuroscience.
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- Customary early AM routine
- Worked my way through a thick stack of messages and situations needing a response--none were inordinately time-consuming, but there was a lot of them. It took the whole morning.
- Stepped out to grab some KFC for lunch, which we ate at home.
- Ran a healthcare-related personal errand.
- Wrestled aggressively with my exegetical notes for Proper 23 and extracted from them a homiletical message statement for my visitation to St Christopher's, Rantoul on October 13.
- Relived the stress created by such labor by taking an equally aggressive and longish walk on a sultry and warm afternoon.
- Evening Prayer with Brenda.
The online diary of the Right Reverend Daniel Martins, Bishop of Springfield (Episcopal Church)
Tuesday, September 10, 2019
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The Meal
A taro root twist on the hearty stew made with boneless chicken, onion, carrots and traditional Mexican spices. Served with roasted jalapeno, queso fresco and green salad. Black beans added for additional carbs.
queso fresco black beans green mix jalapeno nutmeg carrot oregano taro root cumin olive oil cilantro apple cider vinegar red pepper Chicken Black Pepper Celery Onion Sea Salt
Nutrition Facts
Calories: 569
Trans Fat: 26 g
Cholesterol: 142 mg
Sodium: 744 mg
Total Carbohydrates: 43 g
Dietary Fiber: 16 g
Protein: 46 g


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Noelle Hancock / Us Weekly:
Jenna Jameson: My Secret Cancer Struggle — In November 2004, the world's most famous adult film actress, Jenna Jameson, went to the dermatologist to treat some veins on her back, and was shocked when the doctor discovered a misshapen mole that turned out to be malignant melanoma.
Discussion: I'm Not Obsessed, Dlisted, A Socialite's Life, Allie Is Wired, CELEBRITY SMACK!, Best Week Ever, poponthepop.com, Rumors and Hollyscoop
Michael K / Dlisted: Jenna Jameson's Cancer Struggle
Juicy Dirt / Rumors: Jenna Redefines Religion
National Enquirer:
WORLD EXCLUSIVE: LARRY BIRKHEAD'S SECRET GAY LOVER TELLS ALL! — "I was Larry Birkhead's secret gay lover!" — That's the sensational revelation of Kerrick Ross — a handsome male model who carried on a torrid two-month sexual affair with the man who won the blockbuster paternity battle for Anna Nicole Smith's baby girl.
Discussion: popbytes, Dlisted, GlossLip, Celebrity Blog …, Defamer, WOW Report, TMZ.com and Daily. Gay. News.
Michael K / Dlisted: Larry Birkhead's Gay Lover Tells All!!!!
Andy In Larry Birkhead / Daily. Gay. News.: MALE MODEL CLAIMS TO BE LARRY BIRKHEAD'S GAY LOVER
Abby / Yeeeah!:
Larry Birkhead a Gay? — Just when you thought that "As Anna Nicole Turns" had finally come to an end with the revelation of baby Dannielynn's true father, a shady new character emerges to foil the male lead and boost sagging ratings. Stay tuned, because former male model Kerrick Ross …
Michael K / Dlisted: It's Kerrick Ross!
Drudge Report:
COWELL ROLLS EYES AFTER 'IDOL' CONTESTANT SENDS CONDOLENCES — Fans were enraged and FOX affiliates were fielding complaints late Tuesday after AMERICA IDOL judge Simon Cowell was caught on camera rolling his eyes after comments made by contestant Chris Richardson — comments about the tragic VIRGINIA TECH shootings!
Discussion: Seriously? OMG! and Metadish Feeds
SeriouslyOMGWTF / Seriously? OMG! WTF?: A Simon Cowell eye roll causes an uproar
Joe Reality / Reality TV Magazine:
American Idol Results - Sanjaya Malakar Eliminated
American Idol Results - Sanjaya Malakar Eliminated
Discussion: Bumpshack.com and Right Celebrity
Risemoon / Right Celebrity: Sanjaya, Good Riddance
Andrei Harmsworth / Metro.co.uk:
Jolie: I was sexual at nursery age — Angelina Jolie has revealed she was sexually active in kindergarten, saying she took her clothes off and 'made out' with boys. — The 31-year-old said: 'I was a member of a group called the Kissy Girls. I was very sexual in kindergarten.
Michael K / Dlisted: Angelina Jolie Was a Kindergarten Slut
SeriouslyOMGWTF / Seriously? OMG! WTF?: Angelina Jolie started young, really really young.
Jessie / Cele|bitchy: Angelina's Crazy Knife Sex
Michael K / Dlisted:
Give it to Daddy — Celebrity Babylon claims this is the one and only Fantasia taking pictures of herself with a celly. Hey, I think I've seen that ass on Craigslist before! I'm not sure if it's her, but I'm into it. I love a woman who isn't afraid to bust a butt.
Discussion: crunk and disorderly
J. Harvey / A Socialite's Life:
Fantasia Backs It Up — It's Ass Wednesday here at A Socialite's Life. Celebrity Babylon is claiming it has some interesting pics that are supposedly of American Idol winner Fantasia Barrino. And they aren't glamour shots. … Are we still using "bootylicious"? Didn't we call a fatwa on that?
Beyonce Accused of a Musical Cover-Up — Beyoncé Knowles is going to war with a pop star from the past who claims the former Destiny's Child star covered her song, but didn't cover her ass. — According to a lawsuit filed yesterday in Manhattan Federal Court by music administators …
Natasha / Young, Black, and Fabulous: Bashes, Bashes Everywhere — Everybody's having birthday bashes these days:
Miss Chi Chi / URBAN-HOOPLA.COM formerly Platform: DESTINY FULFILLED — Each member of Destiny's Child is on their grind career-wise.
Greysfang / Gossip Rocks Forum: Beyonce is a copycat; gets sued
Miss Tlc / The Wonderful World Of Miss TLC: Beyonce Rips Off
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Jeannette Walls / MSNBC:
Abdul tries diva trip, but passengers just laugh — 'You're no Sanjaya,' one fellow traveler reportedly shouted — Paula Abdul is a sweetie on "American Idol" — but some folks claim she's not so sweet when she's an airline passenger. — Abdul was a diva during a recent flight …
Michael K / Dlisted: Paul Abdul is a Nightmare in the Air
James / Metadish Feeds: Paula Abdul is No Sanjaya
Derek Hail / Celebrity Gossip: Paula Abdul is a Big Star, A**hole
Phil / Egotastic!:
Jessica Biel is Leggy on Letterman — Here's a sight that will hopefully make up for the rest of today's posts. We already know that Jessica Biel has a great ass, and a great rack too, but now we know she's got killer legs to round out the package. — Anyway, she's hot, and she looks great.
Michael K / Dlisted:
Akon Goes Nuts — Akon left a 14-year-old stunned last week in Trinidad when he brought her onstage and pretty much dry humped her ass, throwing her around like a rag doll. — Earlier, he told the audience that he was holding a "contest" with the winner getting a trip to Africa.
Discussion: The Wonderful World …, The Blemish and CONCRETELOOP.COM
Noelle Hancock / Us Weekly:
William & Kate: What Went Wrong — On April 13, newly single Prince William hit the town for a wild night out in London, racking up a nearly $10,000 bar tab and partying so hard that by 3:30 a.m. he "was struggling to stand up," a club source tells Us. — Hours later, news broke …
Discussion: A Socialite's Life and Jossip
Chris Rock Asks Court to Determine Boy's Paternity — Chris Rock asked a court to determine if he's the father of a 13-year-old boy, according to papers filed in a paternity dispute with a Georgia woman. — If he's proven to be the father, Rock wants to "contribute to the support …
Discussion: Bossip
Barry Wigmore / Daily Mail:
Anna Nicole's £250million baby — She looks just like her daddy, underlining what DNA evidence has already revealed. — As the late Anna Nicole Smith's seven-month-old daughter, Dannielynn, makes her magazine debut, the likeness between her and her father, photographer Larry Birkhead, is undeniable.
Discussion: That Other Blog and Celebguru
Aneezshaikh / Celebguru: Baby Dannielynn's magazine debut
Brian Orloff / People.com:
Lindsay Lohan Says Rehab Felt 'Safe' — Lindsay Lohan's adventures in Wonderland had a positive effect, she says, adding that she stayed at the West Hollywood rehab center earlier this year because she "felt safe" there. — Reflecting upon her month-long stint in the addiction-treatment facility …
Discussion: POPSUGAR and Girlretro.com Celebrity …
X17 Online:
Cameltoe Alert! — Jessica rocked two different trends in two nights with two dramatically different results! Night one, in skinny jeans that elongated her legs in a cleavage baring top that showed off her real and spectacular breasts (with a little help from a push-up bra) …
Discussion: Seriously? OMG!
SeriouslyOMGWTF / Seriously? OMG! WTF?: Jessica Simpson is the worst dressed of the day
Hollywood Reporter:
Kinberg has words for 'Hardy' — "Mr. & Mrs. Smith" scribe Simon Kinberg has been tapped to do an overhaul on Fox 2000's "Hardy Men," which Tom Cruise and Ben Stiller are set to topline. — Shawn Levy is attached to direct the big-screen comedy, which follows the grown-up adventures of the Hardy Boys …
Discussion: I Watch Stuff! and Cinematical
Michele Merkin — Here's model Michele Merkin. She's best know as host for The Style Network's "Foody Call". Each week Michele helps make over an average guy by transforming him into a culinary Casanova. She also teaches these geeks the way to a woman's heart. I like the sound of this show!


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When we find ourselves in a different situation than where we want to be, it creates a drive inside us to do something about it. This is our motivation.
The stronger that motivation, the more likely we are to change our situation. We can do that by changing how we see our current situation ("maybe this is not so bad after all") or we can make changes to move towards that better place ("I'm tired of this, let's fix it").
Imagine that you have recently been diagnosed with pre-diabetes. That is not a situation you want to be in, therefore in theory you would make changes to get you as far away from actual diabetes as you can. But in many cases, even when we know things should be done, we continue to do things exactly as we have always done. WHY?!
Many factors influence our motivation and, when it relates to health, Irwin Rosenstock developed a neat model to determine how likely we are to do something about it, or not.
1. seeing it as a personal threat.
Do you really believe that your pre-diabetes could develop into diabetes, or is this something that only happen to other people?
2. understanding how serious it is and the consequences of it.
Diabetes doesn't hurt, until it does. Apart from taking more medication and dealing with the side effects of that, what else do you think happens to your body? Reduced fertility, nerve damage, amputations, heart disease, weight gain...
3. Believing that changing a particular behaviour will reduce the threat.
Because of the genetic component of diabetes, many people think they are bound to be diagnosed sooner or later, no matter what they do. This learned helplessness paralyses any attempts of improvement.
"Why will I watch my food choices?
I will get diabetes anyway, it's in the family."
It also is a way of transferring the responsibility and justifying your habits.
"My food choices and lifestyle had absolutely nothing to do with it, it just happened. I will continue doing things just as I've always done, and hope this diabetes things just goes away."
Well, I'm writing all this here to remind you that:
Hey! What you do, matter!
Not everything in life is under our direct control, but it's not also completely out of hands. Each day you are making decisions that will have an impact on your wellbeing: what you eat, how much you exercise, how you choose to deal with a stressful situation... we may not be the absolute masters of our fate, but we certainly have a lot of say in it.
And if you don't exactly know what it is that needs to be done, you're in luck! I'm here to help. Let's sit down, analyse the situation, pick our battles, and tackle one thing at a time. You don't have to do it alone.
4. the costs of changing are lower than the benefits expected from that change.
You may still believe that this freaking diabetes is definitely not a cool thing, it could happen to you and you know you have the capacity to make changes, but even so... maybe they are all too hard. Maybe your priorities are others that make it ok to live with diabetes. But maybe, just maybe, you might not have really thought about it seriously enough.
It's uncomfortable - It's scary - It sucks!
To take thoughts off your head and put it in perspective, how about writing it down? Make a list that compares:
- the benefits of not changing a single thing (it's easy!)
- the costs of not changing a single thing (It will get worse.)
- the benefits of making changes (I can take control over this sh#t now!)
- the costs of making changes (I will need to focus.)
I find this more elaborated pros & cons list helps to visualise what you are dealing with and might even give you a hint as to where to start.
You can apply this to any situation. Let me know how you go, I will love to hear from you.
By the way, Nailing Nutrition - my signature 6 weeks online program - kicks off on the 9th of April. To learn more and decide if this is for you, click HERE.


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The Snap Election
On April 18th Theresa May took just about everyone by surprise by announcing a General Election, right after saying that the country shouldn't have one on account of the very important Brexit work that we needed to focus on for the next couple of years. With a couple of chunky BCN articles lined up about legislation that was in the middle of being enacted it meant this edition got thrown into a bit of disarray!
Below are three of the candidates who might be out-bi MPs in the 2017 Parliament. In 2015 Westminster elected the largest group of out LGB parliamentarians of any chamber in the world: 32 of the 650 MPs. Will 2017 beat that record?
Brexit Stage Left
So Article 50 has been invoked and this is real, we're leaving. Does it matter for bis? Any more so than the average person living in the UK, that is.
Almost all the changes for the better we've seen on LGBT rights in the past 20 years have come from Europe – from an equal age of consent to workplace protections. Campaigners from the UK had to go to European institutions to establish our right to be treated equally and appropriately in law as UK institutions failed us.
Brexit doesn't come with an immediate price tag attached saying something like, 'leave the EU and the Single Market, oh and reinstate Section 28' – legally it doesn't have an immediate tangible impact like that.
But it leaves us a question of how much harder it might be in future to effect further change. Especially for bi (and trans) people, as the tide of change hasn't brought us quite as far as lesbians and gay men – as reflected in a wealth of statistics on bi experiences from likelihood of experiencing domestic violence to feeling you can be out to workmates without it affecting your career.
We've seen a notable uptick in hate crimes since last June, including but not limited to racist incidents, and hard economic times always seem to bring an increase in that too. Two years of Brexit negotiations (surely accompanied by a growing tabloid whine of "it's been so long, why haven't we left yet?") followed by a likely economic downturn triggered by leaving the EU is surely a recipe for just such hard times ahead.
There's another unknowable knock-on effect in the likely economic downturn, that I'd describe as 'what might have been'.
Bi support, unlike gay and lesbian focused work, has always been volunteer driven, by organisations without budgets and staff. The numbers have ebbed and flowed a little but over the last thirty years at any given time there have been perhaps twenty local bi groups across the UK with a turnover of a couple of grand between them of one shape or another. That, albeit limited, structure of support and bi space came about precisely because the big LG(BT) organisations like Stonewall, the London Switchboard helpline, Manchester's LGF and the like were not taking bisexuality and biphobia seriously.
But now LGBT organisations are at last starting to understand the "B" and beginning to address our issues.
If funding for them falls away further due to pressure on public spending budgets thanks to Brexit, then that proverbial cake we bisexuals were on the verge of finally having and eating can still be snatched away.
The Edge of Change
It has been two months but the dust is still settling from the snap election for the Stormont Assembly on March 2nd.
Regular readers will recall that the Assembly has voted in favour of allowing same-sex marriage – it's the last holdout of "Civil Partnerships Or Nothing" – but the DUP has blocked such proposals from coming into law through "Petition Of Concern" motions.
These are meant to be checks on legislation that would unduly favour either the nationalist or unionist community. They mean legislation can only pass if supported by 60% of the Assembly voting, including at least 40% of each of the nationalist and unionist designated MLAs.
When the votes were counted after the election, the DUP fell from 38 to 28 seats, taking them below the 30 members needed to bring forward a petition of concern.
However one UUP member and the sole TUV party representative are both pledged to block marriage reform – so it looked as though we were still one seat out of ninety short of breaking the block. It would just take one rebel, though. So near and yet so far.
But then marriage became a political bargaining chip as Sinn Fein insisted on it being part of the programme for a new coalition government at Stormont, and in response the DUP equally fervently declared that it could not be.
Talks stalled and attempts to restart them haven't gone well thus far. Northern Ireland looked set to either have a third election in the space of a year, or to have devolved government suspended and direct rule from Westminster restored, when Theresa May made a surprise election announcement of her own. For now, it's all on hold with a rumoured date of 29 June as the next crunch moment; watch this space.


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Here we have a 1969 Pontiac Firebird. This very nice running, driving first generation Firebird is powered by a 6.0 LS Fuel Injected with a 4L80E transmission. Power BMW seats, air conditioning Pypes Performance exhaust system, Foose wheels and Dakota Digital gauges.
* This is a consignment car so there is a 6% additional buyers fee (included in the price above).
Open to offers. Financing available.
The Pick of the Day hones in on the coolness factor
With the introduction of the Chevrolet Camaro in 1966, followed one year later by its mechanical twin cousin, the Pontiac Firebird.
When you think about muscle cars and pony cars of the late 1960s, a 1969 Pontiac Firebird such as the Pick of the Day is not always one of the first cars that comes to mind.
It's no surprise that John Z. DeLorean, who gave us the Pontiac GTO, wanted to do something different with the new Firebird being offered by his Pontiac Division of General Motors.
Mecum Auctions rolls into Southern California on Thursday for its annual three-day sale at the Anaheim Convention Center
I've spent far longer then I care to admit staring at the Pick of the Day car, a 1968 Pontiac Firebird, trying to think of something smart and interesting to say about it.
Still steamed that you missed out on that 1977 Pontiac Firebird Trans Am, the Smokey and the Bandit promo car that sold at Barrett-Jackson?


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10 Health Enhancements of Antioxidants For Athletes
Antioxidants are compounds that naturally strengthen your body cope with excessive levels of toxins. They are unstable molecules that produces cell damage within our physiques along with a probable cause of most chronic health issues today. The advantages of antioxidants are largely misinterpreted and for that reason there are lots of misinformation regarding the subject, which big Pharma and food manufacturers have capitalized on selling numerous questionable supplements to athletes around the world.
How antioxidants work
Toxins may be created within our physiques when normal cell development and processes are altered due to introduced substances for example pollutants and chemicals we touch, within our food or possibly the environment we breathe combined with substance we affect our physiques. They may also be a consequence of radiation on the planet, radio ways along with other radiation furthermore to from exercising.
Antioxidants demonstrated up at our defense because:
- Stable molecules possess a balanced amount of electrons, once they lose an electron they become unstable and have the potential of damaging other cells. Antioxidants can switch the lost electron neutralizing the molecule, they redistribute their unique molecules to stay stable.
- Toxins try and steal molecules business cells to acquire back their balance, to usually create another contaminant that may the shape a collection reaction.
- Intense workout or activity causes the development of toxins when athletes consume foods which are full of antioxidants toxins might be neutralized.
- Athletes who consume foods full of Vit E and c what exactly are best antioxidants find they recover faster than without in order to resume training again sooner.
- During exercise ROS (reactive oxygen species) are created using the skeletal muscles, this is a normal area of the body's strengthening system. Natural antioxidants in wholesome foods supports this method that really help in recovery.
- Natural antioxidants if fresh produce for example beets, berries, eco-friendly leafy vegetables possess a positive effect, but research has states antioxidant supplementation using artificial compounds can negate a lot of the advantages of exercise.
- Getting a diet regime that's wealthy in antioxidants enables you to definitely relieve oxidative stress, this is a product of exercise.
- Anthocyanins, effective antioxidants found in tart cherries, dark berries, along with other red foods happen to be located to provide a considerably better oxygen consumption.
- Research has found that athletes who consume immeasureable high antioxidant foods have benefits for example reduced inflammation markers along with a faster isometric strength recovery.
- Athletes frequently search for strategies to increase vasodilation, the widening and relaxation of bloodstream stream vessels which assists their muscles use longer in a bigger intensity letting them achieve greater levels. Natural nitrates found in foods full of antioxidants are altered into nitric oxide supplement supplements, which assists to boost vasodilation.
The advantages of foods which have antioxidants have extended been recognised due to the proof within the abilities of individuals together rather of folks that don't. They help the body in managing natural toxins produced by exercise additionally to the people from pollutants.


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Hailed as the Golden Age or as the Age of Renaissance, Gupta Empire contributed a lot to India.
In this article on Gupta Empire, we are going to take a quick peek into the various aspects of the Guptas including their art and architecture, paintings, music, languages, society, religion, science and technology etc.
Please note that this article on Gupta Empire doesn't provide a comprehensive list of facts. The major ones are included. So, let us begin.
Art and Architecture of Gupta Empire | 1-6
1. Three major deities were worshiped – Lord Vishnu, Lord Shiva, and Goddess Shakti.
2. Guptas continued the development of caves but addition of mural paintings was a new feature. Some of the caves that boast such beautiful mural paintings are:
Ajanta Caves
Location: Aurangabad, Maharashtra, India.
Time: 200 BCE to 650 CE
Patron: Vakataka Kings
Other important features: It was actually built for Buddhist monks. Of 29 caves, 25 caves were used as Viharas or for residential purpose and the remaining four were prayer halls.
Noteworthy art or architecture: Mahaparinirvana of Buddha in the 26th cave.
Ellora Caves
Location: Sahyadri ranges, Maharashtra, India.
Time: 5th to 11th CE
Patron: Many kingdoms
Other important features: Of 34 caves, 17 were Brahmanical, 12 Buddhist and 5 belonged to Jains.
Noteworthy art or architecture: Kailash Temple dedicated to Lord Shiva is, in simple words, stunning. Present in the 16th cave, the Kailash Temple is an awe-inspiring rock cut temple architecture.
Bagh Caves
Location: River Bagh, Madhya Pradesh, India.
Time: 6th century CE.
Other important features: There are a total of 9 Buddhist caves. They are similar to Ajanta caves.
Junagadh Caves
Location: Junagadh, Gujarat, India.
Time: Not clear.
Patron: Not clear.
Other important features: In reality there are no caves there. There are three sites which are Khapra Kodiya, Baba Pyare and Uparkot.
Noteworthy art or architecture: Uparkot is a 30 to 50 feet high citadel present in front of the prayer hall which is quite unusual.
Nasik Caves
Location: Nasik, Maharashtra, India.
Time: 1st CE.
Patron: Not clear
Other important features: total of 24 Buddhist caves are present which are also known as Pandav Leni.
Noteworthy art or architecture: Depiction of excellent water management system which are indicated by the presence of water tanks made out of solid rocks.
Mandapeshwar Caves
Location: Borivalli, Maharashtra, India.
Other important features: It was actually a Brahmanical cave but was converted into a Christian cave.
Noteworthy art or architecture: Though church and graveyard are present, remains of Ardhanarishwara, Sada Shiva and Nataraja can be still seen.
Udayagiri Caves
Location: Vidisha, Madhya Pradesh, India.
Time: 5th CE.
Patron: Chandragupta II of Gupta Empire.
Other important features: These caves are Brahmanical ones. They are dedicated to Shiva, Narayana, Narasimha and Skanda.
Noteworthy art or architecture: Sculpture of Boar or Varaha (incarnation of Lord Vishnu) is amazing.
Note: It is to be noted that though for some caves, the patron is not clearly mentioned these caves were developed during the Gupta Empire and hence, their contribution to these caves should be understood though not explicitly mentioned.
3. Stupas were not developed with earlier vigor but Dhamek Stupa at Sarnath in Uttar Pradesh, India is a fine example of stupa development during the rule of the Gupta Empire.
4. A new school of sculpture was developed at Sarnath. They abandoned any type of nakedness in sculptures and used cream colored sandstone and metals. A fine example is Sultanganj Buddha.
5. Some of the famous inscriptions from the Gupta Empire are:
Prayaga-Prashasti – Four inscriptions are present. One of them is written by Harisena in Sanskrit language describing the conquests of Samudragupta and the boundaries of the empire.
Mehrauli – The Mehrauli Iron Pillar (in Qutub Minar Complex) was established by Chandragupta II as Vishnupada in the honor of Lord Vishnu. It describes the conquests of Chandragupta against the Vanga (present day West Bengal, Bihar and Bangladesh) rulers.
6. Temple architecture took a major haul during the Gupta period. The developments in temple architecture can be broadly divided into five stages:
First Stage – Temples had shallow pillars, low platform, and they were square shaped. The temples had flat roof.
Second Stage – Temples were built on raised platforms, two-storied temples were also constructed. Pradakshina path was also introduced.
Third Stage – In this stage there was emergence of Shikharas instead of flat roofs. Panchayatan style was adopted for temple making. In this style there were four subsidiary shrines along with the shrine of the main deity.
Fourth Stage – Almost everything was same except the shrine of main deity became more rectangular.
Fifth Stage – Circular temples with shallow rectangular projections was the only change. Everything else remained the same as the fourth stage.
Paintings of Gupta Empire | 7-13
7. Though primitive form of painting can be seen from Indus Valley Civilization sites like Bhimbetaka, Panchmarhi, etc., the concept of painting as an art emerged during the Gupta period.
8. Vatsyayana (during Gupta Empire) in his book, Kamasutra, described about 6 forms of painting which are briefly described below:
Rupabheda – Diversity of form.
Bhava – Creating luster and glow with colors.
Pramanam – Proportion of the particular subject.
Sadrisyan – Portraying the likeliness of the particular subject.
Varnikabhanga – Mixing colors so that it resembles effects of modelling.
Lavanyayogam – Involvement of the emotions.
9. Visakadatta's play Mudrarakshasa also depicts different styles of paintings like Cauka Pitaka (isolated framed drawings), Yama Pitaka (isolated paintings) etc.
10. It is a known fact that Ajanta, Ellora etc. caves are full of amazing paintings and most of them belonged to Gupta period.
11. The paintings are so vivid that one can see emotions even in animals and birds. Another surprising feature in these paintings is that each female figure in a painting has different hairstyle.
12. Some of the famous paintings are Jataka stories, stories of Lord Shiva and his devotees, story of Lord Vishnu with his consort Goddess Lakshmi flying on his vehicle Garuda, stories of beautiful apsaras, etc.
13. Pottery was one of the many things where Harappans were masters. In the similar fashion as paintings, Guptas also took pottery a step further with more decorative designs, and techniques like stamping, molding etc.
Music of Gupta Empire | 14-16
14. Coins of Samudragupta and Kumaragupta show them playing a musical instrument which is most probably a Veena.
15. Guptas were patrons of music. Music has developed quite a lot due to Gupta's patronage.
16. Musical knowledge was generally categorized into four categories which are:
Swaragatam – Knowledge of the seven swaras.
Vadyam – Playing musical instruments.
Samatalam – Knowledge of rhythmic instruments like Pukharaj.
Pushkanagatam – Playing rhythmic instruments.
Languages of Gupta Empire | 17-22
17. Sanskrit language was revived like never before in the Gupta Empire. It was used for writing scriptures, used in academics and it was a major language for literature.
18. Common languages spoken were Sanskrit for literary purpose and Prakrit and Pali (a dialect of Prakrit) for vernacular usage.
19. Panini wrote a book on grammar (relating to Sanskrit language) called Panini Ashtadhyayi. Patanjali's Mahabhashya also contributed a lot to Sanskrit language.
20. A Bengali Buddhist scholar, Chandragomia, also wrote a book called Chandravyakaranam on Sanskrit grammar.
21. It is important to note that Gupta scripts developed from Brahmi. The scripts of Gupta were mostly Nagari (Gujarati script, Devanagari Script – Hindi), Siddham (Bengali, Assamese, Tibetan), Sharada (Gurumukhi script – Punjabi) etc.
22. Hindi, one of the official languages of India, uses Devanagari script even today.
Literature During Gupta Empire | 23-36
23. It was during Gupta period that Mahabharata and Ramayana were compiled.
24. 18 puranas were committed to written texts during the Gupta period (as we see them today). Some of them are Mastya Purana, Vishnu Purana, Shiva Purana, Vayu Purana, Bhagavata Purana etc.
25. Guptas were patrons of education and literature too! Many eminent scholars and poets thrived in Gupta Empire and produced many masterpieces.
26. Kalidasa is one of the most renowned poets and playwrights of India till date.
27. Some of his works of art are Raghuvamsam, Vikramorvashiyam, Ritusamhara, Kumarasambhava, Meghadutam, Abhigyanashakuntalam, Malvikagnimitram, etc.
28. Amarasimha, another great scholar, wrote Amarakosha, a dictionary of Sanskrit words.
29. The famed Panchatantra, written by Vishnu Sharma, belonged to the Gupta period.
30. Varahamihira, one of the greatest polymaths of the world, needs no introduction. He wrote Pancha-Siddhantika which included Surya Siddhanta, Paulisa Siddhanta, Vasishta Siddhanta, Paitamaha Siddhanta, and Romaka Siddhanta.
31. His other work, Brihat-samhita, includes various topics like astronomy, eclipses, planetary motions, gems, matrimony, pearls, domestic rituals etc.
32. He contributed to trigonometry (which is dead now because of the Bibhorr formula formulated by an Indian named Bibhorr), optics, and combinatorics.
33. Other works of Gupta period include Sudraka's Mrichchakatika, Bharavi's Kritarjuniya, Subhandhu's Vasavadatta, and Dandin's Dasamukacharitra and Kavyadarsa.
34. Buddhist and Jain literature also developed during Gupta's time.
35. Buddhist scholars like Arya Deva, Vasubandhu etc. were very famous.
36. Siddhasena Divakara, a Jain scholar, paved way of logic and pragmatic reasoning in Delhi.
Science and Technology During Gupta Empire | 37-51
37. Aryabhatta formulated the area of a triangle. He was the one who discovered algebra.
38. Aryabhatta's value for Pi is more accurate than the value given by Greeks.
39. Aryabhatta gave the place value system for 'zero'. We generally say that he is the one who discovered zero but the truth is that he never gave the symbol of zero (0).
Please note that some say that the 'true zero' was developed by Brahmaguta (another another ancient Indian mathematician and astronomer) long after Aryabhatta. Brahmagupta gave rules of computation using zero.
40. Arabs actually called mathematics "Hidisat" which meant art of Indians. It is from Indians that Arabs learnt mathematics.
41. Indian number system was developed during Guptas' time. This number system was adopted by Arabs. No due credit was given to the creators of the number system as the number system was popularly known as the Arabic numeral system.
42. However, some justice is done as it is now called Hindu-Arabic Number System.
43. Metallurgy was a specialty during the Gupta period. Iron and steel were extensively used. Mehrauli pillar in Qutub Minar Complex stands out as a brilliant example for the high advancement in iron technology.
44. The pillar is rust-free for nearly 16 centuries! Isn't this enough?
45. Melting of metals was known as Dhatuveda. Science of testing gems was known as Ratna Pariksha. Maniragakarjanam meant technology of jewels.
46. During this time, many additions were made to Susruta Samhita. Many herbal medicines and medical instruments were created.
47. Palakava wrote a book on animal and their diseases which was known as Hastayurveda.
48. A treatise on horse, Asvasastra, was also written by sage Shalihotra.
49. Brihatsamhita and Amarakosha had chapters which dealt with study of herbs, plants, crops, gardens etc.
50. Varaha Mihira claimed in his book Brihatsamhita that presence of termites and plants can indicate the presence of water.
51. He listed six animals and around 36 plants that can indicate the presence of water.
Religion During Gupta Empire | 52-58
52. Royal family members were mostly Hindus. They were Vaishnavites (who pray to Lord Vishnu).
53. Lord Vishnu and his avatars gained prominence. Dasavatara concept emerged during this period.
54. Vishnu Sahasranamam (thousand names of Lord Vishnu), Bhagavat Puran etc. were added to the texts of Vaishnavism.
55. Bhakti and ahimsa concepts were given more importance. Hinduism in general was revived during this period.
56. Though the kings were Vaishnavites, other cults of Hinduism and other religions like Buddhism, Jainism, etc. were allowed to flourish equally. Subjects were given religious freedom.
57. Puranas got their final form in this time. Hindu temples were constructed more or less in line with present-day temples.
58. Increase in idol worship and personification of gods and goddesses increased.
Society During the Gupta Empire | 59-69
59. Varna system or caste system was followed.
60. Kings had the ultimate power. Chandalas were seen low and untouchability was also common.
61. Inter-marriages and Inter-dining were not promoted but they were not prohibited as well.
62. Slavery existed but in a milder fashion. Slaves could be freed if they fulfilled certain conditions.
63. Prisoners of wars, drunkards, bankrupt gamblers, servants of royal family etc. were some of the categories of slaves.
64. Foreign tribes like Indo-Greeks, Shaka, Kushana, Hephthalite, etc. were taken into the folds of caste system.
65. Except for the Brahmins, other castes increased in numbers.
66. Patriarchal system was followed and joint families were prevalent. Child marriages were rare. All eight types of marriage like daiva vivaha, brahma vivaha, gandharva vivaha, rakshasa vivaha, paisachika vivaha etc. were common.
67. Status of women declined but they were allowed to be educated and some of the upper caste women participated in cultural and administrative activities also.
68. Upper caste women were allowed to choose life partner via swayamvara. Lower caste women were allowed to work and help in running their families.
69. Polygyny (one man marrying multiple women) was allowed but not polyandry (one woman marrying multiple men). Sati was first recorded in Eran, Madhya Pradesh, India at around 510 CE.
Lifestyle During Gupta Empire | 70-79
70. Most of the people were vegetarians. They avoided foods like potato, tomato, chili, corn, tea, coffee, etc.
71. It was during late Gupta period that chess was invented. It was called Chaturanga. It consisted of chaturangini sena (four arms of an army i.e., elephant, horseman, chariots, and infantryman).
72. This game was introduced to Persia, then to the Arabs and ultimately went to Europe and is now known as chess.
73. Chaturanga is considered as an ancestor of all the board games in the world.
74. Festivals were very important. Religious and agricultural festivals were celebrated with great vigor.
75. Dresses made of cotton, wool and silk were used. Stitched garments were mostly worn by upper caste and royal family.
76. Artificial hair, lipstick, powders etc. were used. Uttariya was worn to cover torso and antariya was worn to cover the lower parts of the body.
77. Many ornaments made of different materials were used.
78. People were very ethical and hence crime rate was very low. Many charitable institutions were in existence. Hospitals were also present.
79. Traveling overseas was considered a taboo and a sin.
Education During Gupta Empire | 80-82
80. Education was given a lot of importance in the society. Primary education was done at home and higher education was completed on agraharas (Vedic schools) or monasteries (Buddhist or Jain).
81. Sanskrit was an academic language and many subjects like astronomy, medicine, mathematics, science of warfare, itihasa, smritis etc. were taught.
82. Ujjain, Pataliputra (present-day Patna), Taxila, Kanchipuram, Varanasi, Nalanda etc. were centers of learning.
Calendars During Gupta Empire | 83-85
83. Many historians believe that Vikram Samvat era was named after Chandragupta Vikramaditya when he conquered Malwa at around 400 CE.
84. This era was actually instituted by Malawa Ganarajya and was known as Malawa Gana era.
85. The calendar used by the Gupta is 56.7 years ahead of Gregorian calendar and it is a lunar calendar. It has 354 days and is divided into 12 months. Some of those months are (Chaitra, Vaisakha, Kartika, Pausha, Magha etc.).
Coins During Gupta Empire | 86-87
86. On one side of the coin, one can see the king making oblations to an altar, or is playing veena etc.
87. The other side of the coin either had goddess Lakshmi on lotus or the queen herself. For the first time in the history of coins, Sanskrit (Brahmi script) was used.


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APPT ONLY! 24 Hour Notice Required!! Request of Seller that Listing Agent be present when showing to open secured doors for Any Viewing. This MAJESTIC Condo with Rooftop observatory deck in Tallahassee Fl, is now available for purchase and is sure to impress every Elite Professional. Description pales in comparison to the breathtaking feeling you experience here. Must visit to appreciate. We have 3 floors completely loaded with features! 1st Floor can be utilized as full working office spaceor lease out to create income! 3k a month potential! 1st floor has extremely impressive conference room or to use as a multi office work space. 2nd Floor is equipped for the FINEST ENTERTAINMENT, Kitchen has 3 bay sink, 2 dishwashers, 3 wine refrigerators, restuarant style main fridge, built in Expresso Coffee Maker, Gas Stove, 2 microwaves, abundance of cabinet space and much much more! This floor also has a 2nd bedroom with a wetbar and 2 full baths. A BREATH TAKING LIBRARY with a gas fireplace for a tucked away comfortable seeting for enjoying books or just relaxation. Last but not least the top floor the Masterbedroom and bath over 900 square feet! Massive walk in closet with washer and dryer, for conveniance, an office off to the side, a huge rain/steam shower in master bath, 4 person jacuzzi. Many more features include solar panels for energy efficiency, a privacy fence, coded doors and real Wood Floors along with high end Italian porcelin floors! Must See Call now for a viewing. Your lifestyle of Luxury overlooking the Railroad Station is waiting. Also the Seller can add the 2 other attached homes for another 600k. Each property rents for 2500 each all are always rented out yearly! and rent out the 1st floor for another 3k, all 3 units will pay the mortgage!
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John Ashton
John has over 100 stage, film, and television credits in his career that spans over 40 years. He has won critical acclaim for his work on such films as Beverly Hills Cop I and II, Midnight Run, Gone, Baby, Gone, and many others. He has also won the same for his stage work for True West and A Flea in Her Ear. John received his B.A. in Theater Arts from the University of Southern California, where he was also rewarded the Irene Ryan Scholarship. He toured Europe with the USA Festival Theater Tour in Germany, England, and at the prestigious Edinburgh Arts Festival.
|Movie Name
|Release Date
|Beverly Hills Cop II English Action Movie Online Watch [1987]
|May 20, 1987


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The most effective distributed relational databases
Relational SQL databases, which have been round for the reason that 1980s, traditionally ran on mainframes or single servers that's all we had. When you wished the database to deal with extra information and run sooner, you needed to put it on a much bigger server with extra and sooner CPUs, reminiscence, and disk. In different phrases, you turned to vertical scalability or "scale up." Afterward, should you wanted the flexibility to fail-over to enhance availability, you would collocate a sizzling back-up server with the energetic server in an "active-passive" cluster, usually with shared storage.
The 4 ACID properties atomicity, consistency, isolation, and sturdiness are required to make sure that database transactions will all the time be legitimate, even within the occasion of community partitions, energy failures, and different errors. It's comparatively straightforward for a database on a single server to evolve to all 4 ACID properties; it's a bit tougher to implement for a distributed database.
NoSQL databases, launched round 2009, supplied horizontal scalability (that means that they might run on a number of servers) however typically lacked full ACID compliance, and often didn't help the SQL language as such. NoSQL databases launched the concept of "eventual consistency," that means that should you wrote to the database from one server and browse it from one other instantly, you may not see the identical outcomes as you'd studying it from the server to which you had simply written. When you waited lengthy sufficient, nevertheless, the brand new information could be replicated to all of the servers within the cluster and would then be constant. Eventual consistency is sweet sufficient for a lot of purposes, akin to on-line catalogs, however not adequate for finance.
Just lately, a number of "scale-out" SQL databases have been launched that are horizontally scalable. Even higher, a few of them can deal with having geographically distributed servers with out sacrificing consistency. Extraordinarily distant server nodes take longer to replace than native nodes due to the restrict imposed by the pace of sunshine, however a number of methods can mitigate that downside, together with using consensus group quora and really high-speed networking and storage.
Generally, the database you've got been utilizing and the brand new distributed database you wish to use must be as suitable as doable to attenuate schema and software conversion prices. Within the easiest case you may migrate your schema and information after which merely change a connection string in your software. In essentially the most difficult case you'll must undergo a knowledge conversion course of, an entire rewrite of your saved procedures and triggers, and a significant rewrite of the information layers of your purposes, together with your SQL queries.


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BMA protests about performance related pay in the NHSBMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6941.1443 (Published 28 May 1994) Cite this as: BMJ 1994;308:1443
The proposal to introduce locally negotiated performance related pay for employed doctors in the NHS will open the way to "unseemly and divisive" local disputes, according to the BMA. In a strongly worded letter to the secretary of state for health, the chairman of the BMA council, Dr Sandy Macara, said that the association had "profound objections" to the government's plans to amend doctors' terms and conditions of service.
Department of Health officials have told the BMA that from April 1995 the doctors' and dentists' review body will recommend only an "exceptionally modest pay" increase for doctors. This would lead local employers to award any further increases according to local performance related pay schemes if they were able to generate sufficient resources to do so through improved productivity.
In his letter to Mrs Bottomley, Dr Macara warns that the degree of control that such schemes offered managers introduced an extremely dangerous principle in medicine. There was a danger that a hospital's performance related pay scheme could give managers a tool with which to pressurise consultants into compliance with trusts' business needs. Far from improving performance, Dr Macara pointed out that there was growing evidence that performance related pay demotivated staff who saw such schemes as "unfair, discriminatory, or unattainable."
The BMA has urged the secretary of state to reconsider the proposal and has said that it is willing to discuss alternative remuneration structures for doctors.
BMA supports medical students over hepatitis B ruling
Prospective medical students should not be screened for the …
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Awesome Tour!
- Tour bus picked the group up at source for sports and they were early which was great. We had Alicia as a tour guide and she was awesome, very informational about Jasper and the surrounding area. She made a point of interacting with every single person in the group which was kind of cool. The tour itself was absolutely stunning. Maligne Canyon is very cool to see in person and I would highly recommend it. The tour is all downhill (minus a few inclines towards the bottom) and is approximately 3km total walking distance.


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Do the Right Thing
If you want to succeed in life, then you must make a commitment to yourself. This commitment entails that you will do whatever it takes to live out your dreams. To go after what you want and to not rest until you have conquered your goals.
I am a firm believer in doing the right thing. In most situations, we know what the right thing is. Still, we manage to make the wrong decisions. This is best illustrated using the following example: you create a plan and are ready to achieve your goals. The right thing to do is to start working and grinding it out. Yet, you find yourself procrastinating. We know what the right thing to do is, but we avoid it!
Another example will resonate with anyone in sales or in a client-facing industry. We know that one of the most vital aspects of success is to reach out to clients. Yet, how often do you postpone prospecting or calls? You always tell yourself that you can do it tomorrow, but you don't. Yes, fear plays a role, but that's not the point. The point is that we know what the right thing to do is! Even if we are fearful of prospecting, then we must spend our time overcoming this fear (the right thing to do) versus putting off essential work for a later date (the wrong thing to do).
When your body tells you what the right thing to do is, then you must do it. You will increase productivity and confidence in your decision making. Being indecisive and lacking initiative are two awful traits that you must eradicate!
I must stress that doing the right thing does not just apply to work. You must adopt this as your core philosophy in life that extends to your family, friends, and community. If you know that a loved one is hurting, then you must be there for them. If your community needs volunteers, then you must offer your time. Doing the right thing makes you a more wholesome individual. You will not only gain the respect of those around you, but you will boost your own self-respect.
When the time comes to do the right thing, do it! Do not hesitate. Do not reschedule. Just do the damn thing. Once you have completed the task, you will feel incredible. The longer you let it sit, the more stressful and anxious you feel.


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