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This article is more than 1 year old
ICANN celebrates ninth anniversary as master of your domain
Here's to you, internet overlords
Today is the ninth anniversary of ICANN as the master of the internet universe, and on that note, the controversial organization that controls the technical standards of internet seems to merit a salutation of sorts.
ICANN was created by the American government to manage the backbone of the internet, and it assumed official control of the net we all know and love on September 18, 1998. From the outset, ICANN was controversial, in part because of the role it fulfills: like it or not, deny it or not, ICANN has the kind of policy-making authority traditionally reserved for elected officials.
As much as ICANN bends over backward to be inclusive - which it does these days - many will never forgive that fundamental flaw. ICANN continues to this day as a California nonprofit corporation, based in a suburb of Los Angeles and perched on a stretch of coastal landfill.
ICANN thus embodies a very contemporary dilemma: how to outsource what traditionally is government work, while maintaining accountability to the electorate? The awkward, unwieldy structure of ICANN - committees heaped upon committees, in an alphabet soup of bizarre acronyms - is only the outward manifestation of this inherent inner tension.
Those who think that this is exactly the kind of authority that is fundamental to governance, and therefore not to be outsourced, will never be satisfied with the ICANN model. It may not be ideal, but it is what we've got, and ICANN's imperfect attempts to involve the public in its decision-making process are nonetheless to be lauded.
Let's hope that ICANN continues in that direction, particularly when it comes to increasing transparency in its dealings with the US Department of Commerce and other governments, with which it consults regularly via representatives on the Government Advisory Committee (GAC).
In furtherance of the goal of expanding public participation in ICANN, we encourage everyone to take ICANN's recent customer satisfaction survey, and tell them what you think. They just might listen.®
Burke Hansen, attorney at large, heads a San Francisco law office


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American. Wild caught. 100 percent domestic. When you buy shrimp from C.F. Gollott & Son Seafood, this is exactly what you're going to get. We take pride in a generational company standard that our shrimp will only be harvested from the Gulf of Mexico. The taste is matchless and freshness is our priority. From God's pond to your plate, shrimp from C.F. Gollott & Son Seafood is the No. 1 quality choice for customers nationwide.

subset: commoncrawl


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With so many great Honda models to choose from here at Honda of Murfreesboro, you may be asking yourself how you can possibly decide on just one of them. While we're here to provide you with as much information as possible surrounding all of our new Honda models, we understand that when looking to buy a new or used vehicle, the only way to get a feel for that vehicle is by getting behind the wheel. That's why, if you're having a hard time deciding on which vehicle you want to make your next, we welcome you to schedule a test drive and take your desired vehicles out for a drive around Murfreesboro today!
Are you in the market for a highly capable new sedan? We encourage you to come take a new Honda Accord or Honda Civic model out for a test drive to experience first-hand the high level of performance, technology, and comfort that each has to offer. Or if you're looking for something with a little more functionality to accommodate your family or your adventurous lifestyle, we offer a great selection of new Honda CR-V and Honda HR-V models for you to test out as well. And with a wide assortment of used vehicles from automakers all over the world, we encourage you to browse through our entire selection and schedule a test drive on the vehicle that appeals to you today!
Scheduling a test drive is quick and easy. Simply fill out your name and number and select the date and time of day that you want you to come test drive any of our wide selection of new and used vehicles. We know that the best way to figure out which vehicle you truly want to make your own is to make the short drive from Smyrna, TN; Lebanon, TN; and Franklin, TN to join us here at Honda of Murfreesboro to view our entire selection of new Honda models and used vehicles in person, and take the model that speaks to you out for a test drive today!


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"The powers not delegated to the United States by the Constitution, nor prohibited by it to the States, are reserved to the States respectively, or to the people." – Amendment X
Thomas Jefferson considered these words, the Tenth Amendment, to be "the foundation of the Constitution." In reality, the Tenth Amendment is much more than that. It is nothing less than the foundation of the entire American experiment, based on the principles of the American Revolution.
When Jefferson penned the Declaration of Independence in 1776, he wrote that the 13 American colonies were "absolved from all allegiance to the British crown and that all political connection between them and the state of Great Britain is, and ought to be, totally dissolved." Contrary to popular belief, the erstwhile colonies were not declaring their independence because of new, radical notions, but because their historic right to self-government had been continually violated by the British Parliament with support from the king.
When the colonies seceded from Great Britain, they did not announce that they were forming a new country. The merely asserted that the colonies were now "free and independent states." In today's usage, a state typically refers to a subordinate political unit within a larger government, but at the time of the Declaration, the word state literally meant "nation." Additionally, the term "congress" at that time signified a meeting of ambassadors from independent nations. So, when the colonies met "in Congress," they were meeting as representatives of sovereign states.
The states continued to jealously guard their independence while writing and adopting the Articles of Confederation, officially uniting them politically. Article II of that document, coming second only to the article that officially named of the union, asserted that "Each state retains its sovereignty, freedom, and independence, and every power, jurisdiction, and right, which is not by this Confederation expressly delegated to the United States."
After their victory over the British, some believed that the government under the Articles was not sufficiently strong to handle the common business of the states. In order to address these perceived weaknesses, a convention of delegates from the states convened in May, 1787. As the task of revising the Articles quickly evolved into writing an entirely new governing document, the delegates to the Constitutional Convention were challenged with giving the new government enough power to carry out a few, specific functions while maintaining the federal, decentralized nature of the union.
The enduring importance of state sovereignty was clearly communicated at the beginning of the Convention, when the delegates rejected the Virginia Plan, which would have created a powerful national government and reduced the power of the states. In rejecting this nationalist plan, the new states were attempting to ensure that they had not just fought off one oppressive central government only to institute another.
As the Convention progressed, the principle of self-government provided the framework for understanding the new governing document. When the Constitution was approved for recommendation to the states, its proponents went home to ensure their home states that their hard-won independence was not in danger. In one of the most famous addresses in favor of the Constitution, Pennsylvania's James Wilson explained that every power "which is not given (to the federal government) is reserved (to the states)."
In Federalist 45 James Madison confirmed the continuing independence of the states, saying "The powers delegated by the proposed Constitution to the federal government are few and defined. Those which are to remain in the State governments are numerous and indefinite." The Constitution's very nature, its proponents argued, was one of limited central power and the expansive autonomy of the state governments.
Despite these assurances, many of the Constitution's opponents were unconvinced. James Lincoln, a delegate to South Carolina's ratification convention, charged that the Constitution "changes, totally changes, the form of your present government." Lincoln continued, "What have you been contending for these ten years past? Liberty! What is liberty? The power of governing yourselves." Lincoln and his fellow opponents to the Constitution concluded that, in its unamended state, the document left too much room for the federal government to interfere with this historical right of the states.
The solution to this disagreement came from the ratification conventions of several states, which suggested the inclusion of amendments that would clearly delineate the restrictions on the federal government's power. Massachusetts was the first state to recommend amendments and, as the right to self-government was the keystone of the American political tradition, an amendment protecting that right was placed first in its list of recommendations. The convention advised, "First, that it be explicitly declared that all Powers not expressly delegated by the aforesaid Constitution are reserved to the several States to be by them exercised."
The conventions of New Hampshire, New York, North Carolina, Rhode Island, South Carolina and Virginia included similar language in their ratification documents. These were clearly not idle suggestions and it is highly doubtful that the Constitution would have been ratified in several of these states, including the influential state of Virginia, had this clarification of the states' powers not been agreed upon.
The Constitution was ratified and went into effect in 1789 and the Bill of Rights, the first ten amendments to the Constitution, was ratified in 1791. Within the Bill of Rights lay the Tenth Amendment, which officially codified into the new federal government the most essential historical feature of American politics, the right of unimpeded self-rule through state and local governments.
Through all of this history, the American people had been particularly distrustful of centralized power. Indeed, of all the problematic features of government, Americans viewed intrusions upon their right to self-government as the height of tyranny and the fiercest foe of liberty. As governments in the United States and around the world have become more centralized, the fears of our forefathers have been realized in increasingly terrible ways.
Today, our impulse is to address the problems created by centralized power by using the central power itself, an impulse that is a little like attempting to cure a snake bite by letting the snake bite you again. To recapture the liberties we once possessed we must understand, as our founders did, that the solutions to our current problems will not be found through nationalized power. The only task that centralized power effectively completes is the oppression of its people.
To move forward towards liberty we must look backward to the Tenth Amendment. In its institutional safeguards against centralized power is found the only true protection of our liberties.
- Look in the Mirror - November 5, 2015
- Compact of the Republic - April 20, 2015
- The Un-American Empire - July 8, 2014


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Kicking and Screaming is a slapdash comedy with uneasy tone shifts and uneven performances. The first half of the movie is low on energy and utterly lacking in finesse. But something happens halfway through the movie: star Will Ferrell cuts loose, unleashing the "suppressed rage" of soccer-dad Phil Weston. Suddenly, we're in a cauldron of blood and coffee and Gatorade. Once Kicking and Screaming hits this stride, it's difficult not to laugh at this comedy of man-urge.
Phil's son Sam (Dylan McLaughlin) is a little-league soccer player for the intimidating Gladiators, coached by Phil's rapacious father Buck (Robert Duvall). When Buck "trades" (or, rather, gives away) Sam to the misfit Tigers, circumstances conspire to find Phil reluctantly coaching his son's team. The stakes are heightened by the competition between Phil and his father, who has always beaten his son at everything (adding insult to injuries, he says of Phil, "I love him like a son"). Bellowing on the field and chuckling and gloating around the house, Duvall's passive-aggressive bastard easily makes enemies, including his next-door neighbor: Super Bowl championship football coach Mike Ditka of the Chicago Bears.
Duvall's measured, avuncular menace is a hoot, and Ditka literally acquits himself admirably, but the movie belongs to Ferrell. At first, Ferrell grotesquely overacts (in close-up) as he tries to hold together the domestic exposition of a weak script by Steve Rudnick & Leo Benvenuti. The writers fail to build an original comic scene which capitalizes on Phil's lack of coaching knowledge: he shows up unprepared (reading from a book on soccer), and the kids run rampant. "Why," Phil shrieks at one point, "is everyone slapping me lately?!" The answer is that he's a complete mess, characterized by well-intentioned but utterly inept and annoying behavior.
With the exception of Steven Anthony Lawrence as a team clown, the 10-to-12-year-old Tigers are defined only by stereotypical signifiers: one kid's only trait is that he's willing to eat a worm. Their weaknesses serve as reflectors for Phil's failure and festering stresses. Phil's not exactly healthy at the outset (his panic attacks resemble heart palpitations), but when Ditka casually introduces the caffeine teetotaler to coffee, trouble is clearly brewing. With the help of Ditka and the recruiting of two Italian butcher's apprentices, the Tigers begin to win, but Phil's caffeine-fueled obsession alienates the team and particularly Sam, who finds homself bench-warming once again.
Phil's new heights of annoyance suddenly become absurdly funny, as his bad behavior—paired with the team's success—turn him into a cruel and unrelenting monster. Guzzling cappucino, Phil yells at the kids when they fail to get the ball to "the Italians" fast enough, threatens to eat one of his underperforming players (Elliot Cho's pint-sized Byong Sun), and shoves a child competitor to the turf. The spectacle of Ferrell bop-bopping "Get Ready for This" on the sidelines in a tiger-striped, sky-blue sweatsuit is enough to lift the half-hearted kiddie sports comedy into happily crazed comic territory.
These outrageous gestures fly exactly because they are in the "safe" context of a family comedy, established (but never truly felt) in the first half of the film and just as swiftly restored to order in the film's final moments. Ferrell's underlying sweetness assures audiences that the nightmarish soccer dad of the news is only a bad dream here, and paternal love finally gives Sam the license to show his stuff on the field (I suppose it would be some kind of screenwriting crime if Sam actually did suck at soccer).
More unsettling are the familiar conflicts of machismo between the hard-ass dad and his loser son (in an amusing idea that only steps up in the film's waning moments, the "good son" with whom Phil must compete is Bucky, a star Gladiator that's the same age as Sam). Being a successful businessman and a loving son and father aren't enough: it takes a pillage—only by hurting his father's feelings (by threatening to supplant his manly authority) can Phil win his grudging respect.
Given the Bad News Bears paradigm director Jesse Dylan works here, Kicking and Screaming will surely appeal to kids. Good sportsmanship gets played for laughs, but on a child's level, the messages are mostly clear: both teamwork and self-respectful skill-building are cool, and adults don't know what they're doing (so don't take offense at their bad behavior). Kids will have to find out for themselves that the real Dr. Jekylls of the little-league soccer field don't revert to Mr. Hydes so easily.


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JUNEAU (AP) — The Gulf of Alaska trawl fleet faces new restrictions, as fisheries managers seek to limit the number of chinook salmon it unintentionally takes.
The North Pacific Fishery Management Council passed a policy over the weekend that lowers its cap on bycatch of the fish. It's expected to take a year and a half before the federal government formally adopts the policy, APRN reported.
The trawl fleet comprises about 50 vessels, fishing for things like cod and rockfish, and bringing their catch to seafood processing plants in communities like Kodiak.
Bycatch in the fishery has ranged from 3,000 to 10,000 fish. The question facing the council was how many chinook salmon the trawl fleet could unintentionally kill before it would have to stop fishing. The council settled on 7,500 as the new cap.


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This mod offers two new possibilities to consider when making the decision about whether to side with the Shadow Thieves or with Valen's Mistress. In addition to the traditional two, the player may now opt to side with a group even the paladins in the party could have no objection to... or he may opt to skip the whole decision entirely and set sail for Maztica.
Alternatives also offers a different way to satisfy Mae Var's demand that the protagonist steal an artifact from a temple.
It is nearly impossible for a lawful good character to go through the game and remain completely true to his or her alignment. Siding with thieves is not a very lawful thing to do, nor is allying with undead a particularly good deed. The "Paladin Route" offers a third option, the ability to work for an unimpeachably good organization and eliminate two evils. The "Assassin Route" came about a bit later, as a result of some musing about how a character who has no real interest in either rescuing Imoen or going out of his or her way to take revenge on Irenicus might want to avoid the whole decision entirly and get the hells out of Amn. Jastey never liked the concept of stealing prized artifacts from temples while running errands for Mae Var, so she created a work-around for that, as well. The latter component is also incorporated in Jastey's Ajantis mod, so Ajantis is installed, the "Temple Thievery Alternative" component will not be installed.
Both new options begin after Valen and Brus make their traditional appearances. To begin the "Paladin Route," visit the Government District after speaking with Brus. To begin the "Assassin Route," go to the Slums, where a garishly dressed nobleman by the name of Malficus will make an attractive offer. He is standing outside the Copper Coronet, not far from the road that leads to the southern entrance to the Slums.
Once the protagonist has committed to performing the first task of the "Paladin Route," all other paths are disabled, but it is possible to do two of the three tasks Malficus sets before you and then change sides.
To access the "Temple Thievery Alternative" options, speak to people in the temple about your concerns.
SUGGESTIONS: When one deals with dishonorable people, some treachery and double-dealing is only to be expected. Also, when embarking on a new venture, it is always advisable to tie up loose ends first. Thieves, especially, or those wishing to get to know Renal Bloodscalp a little better or recruit a certain Red Wizard, would be well advised to complete all thieves' guild tasks prior to going to the Five Flagons in or making any final arrangements with Malficus. The quest givers of both routes will warn you when you are approaching the point of no return.


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Ahhh this book, do you remember me telling you it arrived on Saturday? It came aaaaaalllllll the way from Japan you know, and for some inexplicable reason this makes me feel incredibly excited. First time I've ever had anything arrive All The Way From Japan before. I keep thinking how bloomin marvelous it is that I can see something on my computer screen, make a few clickety-clicks on my keyboard, then hey-presto less than a week later a plop through my letter box brings it right into my excited hands. Can you tell I'm a newbie at International Internet Shopping?
Anyhow :: this book....let me tell you now, I've fallen truly, madly, deeply in L:O:V:E with it.
It is quite simply GORgeous. Stunning. Inspirational. Beautiful. Desirable.
Oh yes it is all those things and many more besides and I am seriously in love.
This is what greets you when you first tiptoe into the pages..............
Oh oh OH!!!!!!!!!!!!!!!
Mm mm MMMMMMMM!!!!!!!!!!!
Isn't that just the stuff of anyones Hooky Yarny Dreams???????
I fell in love right there and then, at the sight of that first Double Spread.
Just like that.
Want to see some more??
Want to see some of the projects within these delicious Japanese pages?
A perfectly perfect Attic24-stylie bag.
The most beautiful, beautiful crocheted clothes hangers.....
....just look at that amazingly pretty edging!!And this, one of my absolute favourite pages in the whole book. Love everything about this image, isn't the styling to die for?? That shelf with those teapots!!! OH how I Love that!! Not to mention the beautiful hexie blanket there....
Isn't that design just amazing?Love it.
Now as you know, this book came All The Way From Japan, meaning it is a Japanese book.Meaning it is written in Japanese.
Of course.
But fear-ye-not, because the patterns for all these desirable projects are written in Universal Diagram format, as show above. Lots of gobbledegooky Japanese writing as well, but we can ignore that and concentrate on the diagram....
....which is actually pretty straight forward to follow.
Now if anyones interested, I would gladly write a post about these diagrams, explaining the symbols etc and how to read them, cos thats Very Useful Knowledge to have if you're into crochet.
This afternoon, I had a little go at reading the above diagram and making a hexagon, well five rounds of one anyhow....
....and it didn't turn out too bad, although I think I would need to practice my joining techniques as it's a little messy where each round begins and ends.
Now before I toddle off to go drool some more over the pages, let me give you a few details....
I first saw this book mentioned by Jane. And then by Hen. And it was indeed the lovely Hen who kindly told me where I could go to find this book and purchase it All The Way From Japan.
It came to me via an amazing Etsy Seller called Pomadour24. Super fast delivery, and beautifully packaged too. I think it cost me about £19 including delivery.
The book itself is called "Pretty Colour Crochet and Knit Goods"
Do go take a look at this amazing Etsy shop, there are some lovely looking books to be had All The Way From Japan. (just spotted this one oooo-ooooo!!)
Hmmm....I can feel an addiction coming on. Dear oh dear.
Just to let you know that Pomadour24 does restock/update her etsy shop very frequently, so if the book is out of stock when you first go look, do check back again in a day or two as it will come back in again.
Also to add I've gone and bought Book 2. Dear-oh-dear. I'll show you it when it arrives All The Way From Japan.
And finally, due to popular demand, I will be writing a How-to-decipher post for the crochet diagrams, sometime this week I hope.


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I love quesadillas. A few jalapenos, a bit of red onion, some coriander and a handful of cheese melted between a couple of tortillas is a near instantly gratifying meal. Up until I read this I didn't realise people made them any other way but the thought of fresh masa with the same fillings sounded great. I've also just recently stocked up on masa harina so it was obviously meant to be. My tortilla press was like a pasta machine, bought with the best intentions the gadget got used once and then stuck in the back of cupboard, making for the most expensive pasta/corn tortillas in the history of the world. Here was a perfect opportunity to get it out again though.
I tend to use cheddar for quesadillas as it is always in the fridge but I turned to mozzarella for these as it is far closer to the stretchy oaxaca cheese they'd use in Mexico. The last thing you want is a load of liquid in your quesadilla so this is a rare time I'd use the harder dry blocks of mozzarella over those stored in bags of liquid. These quesadillas obviously take a lot longer to prepare than sticking some cheese in a wheat tortilla but I'll certainly do it again, even if the preparation time means they definitely won't replace my current versions. The resultant quesadillas have a lovely flavour from the masa harina and the fresh dough aspect creates a softer, slightly breadier texture that feels altogether more homemade.
Masa Quesadillas with Mushroom and Roasted Chili Recipe
Makes 6 quesadillas
135gr masa harina
160gr hot water
1/2ts salt
125gr mozzarella
12 mushrooms
1 clove garlic
3 green chillies
A Salsa Fresca
2 ripe tomatoes
1 small red onion
1/2 small pack/12.5gr coriander
Juice of 1/2 a lime
For the masa mix the salt and masa harina together then add the water. Knead for a few minutes until smooth then wrap in clingfilm and leave to rest for an hour.
For the salsa dice the onion and tomato and finely chop the coriander. Mix together, squeeze on the lime juice and season to taste.
Roast the green chilies either under the grill or directly in the flame of your gas hob until black all over then put in a bowl and cover it with clingfilm, this will help loosen the skins. After a few minutes you should be able to remove the skins easily. Take off the stem, remove the seeds and shred.
Slice the mushrooms then fry in a little oil with the garlic until cooked.
The Quesadillas
Take a sixth of the dough and flatten, between two sheets of plastic (I split a ziplock bag), in the tortilla press. Fill with a sixth of the cheese, mushrooms and roasted chili. Fold over and dry fry for 2-4 minutes a side until cooked. By using a small frying pan with the quesadilla pushed against one side you can create the nice rounded edge.
Serve with the salsa and other other condiments you like - I'm thinking the usual sour cream, chili sauce or guacamole.


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A southern resident orca known for carrying her dead calf for nearly three weeks is pregnant again, say researchers.
In 2018, orca J35 or 'Tahlequah's' 'tour of grief' captured global attention as a visceral representation of the endangered southern resident population, of which only 73 whales are estimated to remain.
Aerial images captured earlier this month by scientists from SR3 (Sealife Response, Rehabilitation and Research) identified pregnant orcas in all three southern resident pods (J, K and L), but the organization says this doesn't necessarily mean there will be a baby boom for the dwindling orca pods.
READ ALSO: Orca's 'tour of grief' over after carrying dead calf around for nearly 3 weeks
"This is not unusual," says a press release from SR3. "And unfortunately the majority of recent pregnancies have not resulted in successful births."
Known for carrying her dead calf for 17 days in 2018, southern resident orca J35 or Tahlequah, is pregantn again. (SR3 SeaLife Response, Rehab and Research and NOAA's Southwest Fisheries Science Center in 2019 and SR3 and Southall Environmental Associates in 2020; both collected under NMFS research permit 19091) |
Reproduction failures are typically linked to malnutrition caused by shrinking salmon numbers, SR3 notes. Pregnancy in killer whales lasts up to 18 months.
"We hope folks on the water can give the southern residents plenty of space to forage at this important time. With such a small population … every successful birth is hugely important for recovery."
In 2019, the Canadian government implemented a mandate for boats in the Salish Sea to maintain a 400-metre distance from orcas in an effort to lessen the effects of disturbance and underwater noise pollution. In 2020, foraging and extended sanctuary zones were implemented, including an area based fishery closure for critical habitat areas in the Strait of Juan de Fuca and near the Gulf Islands.
The Department of Fisheries and Oceans asks boaters to slow down below seven knots or less and stop fishing within 1,000 kilometres of orcas. Those on the water can also help by turning off echo sounders and fish finders when they are not in use.
READ ALSO: Three southern resident killer whales declared dead plunging population to 73
Do you have something to add to this story, or something else we should report on? Email:email@example.com. Follow us on Instagram. Like us on Facebook and follow us on Twitter.


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Whether you're on the go with baby or out on the town, this fashionable clutch style wet/dry bag is the perfect accessory.
Use the Clutch to carry a single diaper change or extra clothes for baby. Perfect for cosmetics or toiletries, the clutch is a great addition to your luggage when traveling or to send with the kids for sleepovers. Throw in your wallet and voila – a purse! Carry a notepad and markers in a Clutch to keep the kids busy.
A zippered "dry" section separates your cosmetic brushes, pencils, etc. from your liquids, powders, or lotions. The "wet" section has the same great "waterproof seam" design!
What you'll LOVE about the Wet/Dry Clutch!
*PVC-free and lead-free zippers.
*Anti-microbial interior.
*Reusable to avoid using plastic bags, helping to protect our planet.
*Made in the USA
*Perfect size for travel. Add to your purse or luggage to keep wet or breakable items separate from other items.
*Made with high quality designer fabrics with coordinating waterproof inner material and locking zipper.
*Each bag is innovatively sewn with hidden seams and sealed for no wicking or leaking. First and ONLY in the industry! Patent pending waterproof design.
*Resists most stains and odors – keeping smells in.


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Right-to-Work: What Now for Schools?
Michigan is now the 24th state to outlaw firing employees for not financially supporting unions, making it a right-to-work state.
While this concept is not new, bills making it possible moved quickly through the Legislature. School officials unfamiliar with the policy might be asking: "What now?"
It boils down to this: Districts may no longer sign union contracts that contain "union security" clauses — agreements to fire or extract union dues from non-union members. But nothing will change in the immediate short term. The law does not go into effect until the end of March, and even after that, the law does not apply to contracts signed before that date.
But unions aren't likely to sit on their hands between now and then. School officials should expect them to actively try to open up negotiations and seek long-term contracts that lock in these forced dues. Union officials will likely offer unprecedented levels of concessions to sweeten the pot.
While these long-term deals might appear attractive, school officials should be cautious. One lesson of the Great Recession roller-coaster ride is that districts need more financial flexibility, not less. If districts roll the dice and sign long-term deals, there's no going back. Unions will do everything in their power to prevent reopening the contract again, because it could mean they'll lose dues revenue.
Sadly, this union tactic to protect a funding stream will likely harm the best interests of the members they claim to represent. For starters, delaying the implementation of the right-to-work law would deprive a considerable number of employees of something they may value: the right to choose to support their union.
Additionally, if unions offer concessions to entice boards to extend contracts, school employees will have to pay the price. Obviously, for districts struggling financially this may be needed, but unions might go further than this to protect their interests.
An extended contract might also artificially limit what teachers and other school employees could earn in the future. If Michigan's economy continues to improve, schools may see a boost in funding. But since unions would resist opening up these contracts, school employees may not be able to benefit.
On the whole though, not much will change for school districts as a result of Michigan's right-to-work law. They'll still be required to bargain with established unions under largely the same rules.
But districts could benefit if unions, now having to earn their employees' support, pay closer attention to the interests of their members and represent these at the bargaining table. A more satisfied workforce is in the best interest of every district.
Michigan Capitol Confidential is the news source produced by the Mackinac Center for Public Policy. Michigan Capitol Confidential reports with a free-market news perspective.


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[Ben]'s been at it again. This time he's whipped up a PS3 laptop. He built this one just for engadget… and there will be how-to's on it, oh yes, there will. For now, you can wet your appetite for console modding with the picture gallery. It's pretty big, but It's actually thinner than the original console.
18 thoughts on "Ben Heck's PS3 Laptop"
and it only weighs in at a feathery 16 lbs!
Well it looks nice and as usual shows he's got skills.
But once again WHY WOULD YOU WANT TO DO THIS?
I hate Ben Heck
Looks excellent as always, Ben Heck does amazing work, I for one would love a ps3 laptop. I need a linux laptop for work anyhow and being able to play the odd ps3 game or bluray movie @ lunch would be nice.
Its "whet your appetite"… just for future reference :)
http://www.wsu.edu/~brians/errors/wet.html -
i posit that ben heck is some sort of alien. or cyborg. his work is too clean and snazzy to be merely human.
he worked on it for a year and a half? wow, this guy's got way too much patience.
"wow, this guy's got way too much patience."
either that or he has wayy to much time.
Once again, Ben proves that you can never go over the top. This mod is slick, sexy and just freakin' awesome. Way to go, Ben, that makes all three current-gen consoles. I can't wait to see what you do with the nigh-announced next-gen.
I just thought I should try and warn all of you against visiting benheck.com. AVG detected five instances of the virus "JS/PSyme" on the main page (accessed 2008-04-12 @ 0113 EST).
Screenshot: http://img443.imageshack.us/img443/4523/virusbenheckcomno5.png
judging by the photo you sent, you were infected before visiting benheck.com. your antivirus must have misinterpreted. a quick google search says it came in through a malicious java site, and is nondestructive.
The page load was temporarily suspended each time AVG detected the virus and asked me what to do about it. Therefore, I'm pretty sure it came from something on the main page of benheck.com.
Ben heck is the man.
I propose we make a statue of him and then modify the statue to make it more portable, and then make a statue of _that_.
The resulting statue will be put on display at the Smithsonian museum, or at a really cool park somewhere or something.
He must be keeping up with his dexedrine or adderall therapy to keep with a project for that long.. lol :)
if there was a way to get one of his inventions i would jump through hoops to get one. the ps3 laptop has to be the coolest thing i have ever seen. i need one.
Definitely an awesome laptop. I would definitely buy one of these if they were available on the market. Keep up the good work.
Sometimes the patience and the hardwork bears a magnificient thing. This is just amazing.
that's really cool
i was looking at the pix gallery and was kinda sad that it didn't have a HDMI out tho.. for kinda portable gaming on a big screen !!!! -
Well, its 2011 and no full tutorials on how to make one. unless you have a slim your gunna have to try to make your own with the ps3 phat…
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What's Hot
What's Hot
News flashes are posted here frequently to keep you up-to-date with the latest advances in health and longevity. We have an unparalleled track record of breaking stories about life extension advances.
Benfotiamine may help treat uveitisThe fat soluble form of vitamin B1 known as benfotiamine may help combat uveitis (inflammation of the eye's uvea), one of the world's most common causes of blindness, according to research published in the May, 2009 issue of the journal Investigative Ophthalmology and Visual Science. Scientists at the University of Texas Medical Branch at Galveston injected 12 rats with bacterial toxins that produce a reaction similar to that of human uveitis. Twelve animals served as controls. Half of the animals in the uveitis group were given benfotiamine three hours prior to and immediately following administration of the bacteria. Six animals in the control group also received benfotiamine. Infiltrating white blood cells, and inflammatory cytokines and chemokines were elevated in the aqueous humor of the eyes of the animals in which uveitis was induced, however, these effects were blocked by benfotiamine. The researchers determined that the vitamin suppresses the activation of a signaling molecule known as nuclear factor-kappa beta (NF-KB), which is involved in inflammation. Since reactive oxygen species mediate inflammatory signals associated with infectious agents, benfotiamine's strong antioxidant action may be responsible for the downstream effects observed in this study. "Benfotiamine strongly suppresses this eye-damaging condition and the biochemical markers we associate with it," senior author and University of Texas Medical Branch associate professor Kota V. Ramana stated. "We're optimistic that this simple supplementation with vitamin B1 has great potential as a new therapy for this widespread eye disease." "Already, clinical trials have shown that benfotiamine is absorbed better than thiamine [the most common form of vitamin B1] and significantly improved diabetic polyneuropathy in patients, and it's already taken as a supplement for diabetic complications," he added. —D Dye Long term pomegranate consumption could help slow the growth of recurrent prostate cancerThe 104th Annual Scientific Meeting of the American Urological Association, held April 25-30, 2009 in Chicago, was the site of a presentation concerning the results of a clinical trial which found that pomegranate juice retarded the progression of prostate cancer that recurred following treatment. The trial, which was reported in the April, 2009 supplement to the Journal of Urology, included 48 patients who experienced rising levels of prostate specific antigen (PSA) a marker of prostate cancer, following surgery and/or radiotherapy for prostate cancer. Beginning in 2003, subjects drank 8 ounces of pomegranate juice per day for up to 6 years. Follow-up examinations conducted every 3 months ascertained PSA levels and other data. Interim results published in 2006 in the journal Clinical Cancer Research, revealed an increase in the length of time it took for PSA levels to double when PSA doubling times at the beginning of the study were compared with those following treatment. The current research found that patients who elected to remain in the study experienced significantly increased time to PSA doubling and a greater decline in median PSA slope, indicating slower progression of the disease, when compared with those who did not continue treatment. In a third phase of the trial, the effects of pomegranate juice are being compared with a placebo in a multicenter, randomized trial. "This study suggests that pomegranate juice may effectively slow the progression of prostate cancer after unsuccessful treatment," said Christopher Amling, MD, who is a spokesman for the American Urological Association. "This finding and other ongoing research might one day reveal that pomegranate juice is an effective prostate cancer preventative agent as well." —D Dye Grapes protect hypertensive rats from heart failureIn a presentation at the 2009 Experimental Biology convention in New Orleans, E. Mitchell Seymour, MS, of the University of Michigan, revealed the finding of a cardioprotective effect for grapes in a rodent model of hypertension. High blood pressure can, over time, damage the heart, leading to heart failure. A team from the University of Michigan Cardiovascular Center tested the effect of a blend of powdered green, red, and black table grapes on rats bred to develop hypertension when given a high salt diet. The animals were provided with high or low salt diets and with or without 3 percent grape powder by weight. An additional group of rats provided with the high salt diet were given the blood pressure drug hydrazine. After 18 weeks of treatment, rats on the high salt diet that received powdered grapes had reduced blood pressure, improved heart function, and less heart muscle damage compared to those that did not receive grapes. Those that received hydrazine also had a reduction in blood pressure, but the drug did not protect their hearts from damage. In a report of the findings, which was published last year in the Journal of Gerontology: Biological Sciences, the authors remark that since grapes and hydrazine both lowered blood pressure in this study, the mechanism of grapes in protecting the heart is evidently more than that of reducing hypertension. Rats that received grapes were found to have increased cardiac levels of glutathione, an antioxidant amino acid that protects the heart from hypertension-induced oxidative stress. The authors explain that "Bioavailable grape phenolic phytochemicals may activate cardiac genes, which modify glutathione dynamics, like glutathione peroxidase and glutathione-S-transferase." "There are the small changes that diet can bring, but the effect of grape intake on genes can have a greater impact on disease down the road," Seymour stated. —D Dye Aging biomarker associated with hypertension and coronary artery diseaseThe April, 2009 issue of the American Heart Association journal Hypertension published an article describing the discovery of a link between shorter telomeres and the development of coronary artery disease in men and women with high blood pressure. Telomeres are structures which cap the ends of chromosomes, helping to stabilize them. Telomere shortening limits the life span of cells, and is considered a marker of aging. Researchers at the Chinese Academy of Medical Sciences in Beijing sought to determine the relationship between telomere length and the risk and prognosis of hypertension in Chinese men and women aged 30 to 80 years. Leukocyte (white blood cell) telomere length measured in 388 participants with hypertension and 379 healthy control subjects revealed shorter telomeres in older subjects than those who were younger, and significantly shorter telomeres in those with hypertension compared with subjects whose blood pressure was normal. Complications resulting from hypertension, including stroke, coronary artery disease, hypertensive heart disease, hypertensive renal disease, and hypertensive retinopathy were documented among the subjects over 5 years of follow-up. Participants with shorter telomeres were found to be more than three times as likely to develop coronary artery disease compared with those who had longer telomeres. Additionally, among control patients with normal blood pressure, those who developed hypertension or coronary artery disease over the course of follow-up had shorter telomeres than subjects who remained healthy. Analysis of the data confirmed that both short telomeres and high blood pressure were independent risk factors for developing coronary artery disease. "Our data suggest that mean leukocyte telomere length is a potential predictor of coronary artery disease and support the hypothesis that differences in biological aging can contribute to the risk and variability of developing hypertension and cardiovascular diseases," the authors conclude. —D Dye Lung tumors destroy cancer-fighting vitaminAt the 100th annual meeting of the American Association for Cancer Research, held April 18 to 22, 2009 in Denver, Pamela Hershberger, PhD, of the University of Pittsburgh Cancer Institute (UPCI) revealed that lung tumor cells eliminate vitamin D, a nutrient that has been associated with anti-cancer activity. Dr Hershberger and her colleagues previously discovered that an enzyme which breaks down 1,25-dihydroxyvitamin D3 (the active form of vitamin D in the body) is significantly overexpressed in lung cancer. Inhibiting this enzyme was demonstrated to increase the potency of vitamin D3 to suppress cell growth in studies using cultured cells. "High levels of vitamin D help the body produce proteins with anti-tumor activity," explained Dr Hershberger, who is a research assistant professor at UPCI's Department of Pharmacology and Chemical Biology. "We've discovered that lung cancer cells make an enzyme called CYP24, which counteracts the positive effects of vitamin D. To better study it, we developed the first radioactive-free assay that measures the amount of vitamin D in tissues and blood." For the current research, mice that received implanted lung tumors were given 1,25-dihydroxyvitamin D, and tumor and plasma levels of the vitamin were analyzed periodically over the following 24 hours using the new test. The team found that the peak concentration of vitamin D achieved in the tumor induced a rapid increase in CYP24 . Analysis of the data resulted in further evidence that reduced tumor concentrations of vitamin D were attributable to increased expression of the enzyme. "We hope this new assay will help identify the best approaches to maintain therapeutic levels of vitamin D in tissues," Dr Hershberger stated. She predicted that vitamin D could one day be used as a preventive agent for this deadly form of cancer. —D Dye Longevity-linked pathway studiedIn an article published online on April 16, 2009 in the journal Science, researchers at the University of Washington report their discovery of a mechanism involved in a biochemical pathway that, like the pathway involved with calorie restriction, is associated with longevity. Ranjana Mehta and colleagues at the University of Washington in Seattle had observed in previous research with worms that calorie restriction, which extends the life span of laboratory animals, prevents the toxic protein aggregation that occurs in the brain cells of humans with Alzheimer's and Huntington's disease. In the course of their investigations, the researchers found that the hypoxic response, which is a protective reaction within the cell to a reduction in oxygen levels, is a separate longevity pathway than that associated with calorie restriction. Worms that have the ability to active the hypoxic response live longer and are free of toxic protein aggregation. The hypoxic response is controlled by a protein known as HIF. When HIF is degraded in reaction to another protein known as VHL-1, the hypoxic response remains inhibited when oxygen levels are adequate. In the current research, Dr Mehta and his associates found that worms bred to lack VHL-1 lived 30 percent longer than worms that made the protein. The worms were also found to be resistant to the toxic protein amyloid beta that aggregates in the brains of Alzheimer's disease patients, and to have lower levels of the age-related pigment lipofuscin. "This is a completely new pathway for aging and age-associated disease," noted senior author Dr Matt Kaeberlein, who is an assistant professor of pathology at the University of Washington. "If we can understand at a very detailed level how HIF is slowing aging, we may be able to use that information to develop effective therapies for treating age-associated diseases in people." —D Dye Melatonin helps manage sleep disorders in autistic childrenThe April 15, 2009 issue of the Journal of Clinical Sleep Medicine reported that supplementation with the hormone melatonin reduce the time it takes for children with autism spectrum disorder and/or fragile X syndrome to fall asleep. Fragile X syndrome is the most common form of inherited mental retardation as well as the most common known cause of autism, and is, along with autism, frequently associated with problems falling asleep and staying asleep. "Sleep onset problems at the beginning of the night are very troublesome for children and their families," commented lead researcher Beth L. Goodlin-Jones, PhD of the Medical Investigation of Neurodevelopmental Disorders ( M.I.N.D.) Institute at the University of California Davis Health System in Sacramento. "Sometimes children may take one to two hours to fall asleep and often they disrupt the household during this time." Acting on the hypothesis that children with autism and fragile X-related sleep disorders may have abnormal melatonin levels, Dr Goodlin-Jones and her associates enrolled 5 children with autism, 3 with fragile X syndrome, 3 with both conditions, and 1 with fragile X permutation. Participants were randomized to receive 3 milligrams melatonin or a placebo before bedtime for two weeks, after which the treatments were switched for another two weeks. Sleep duration, sleep onset time, sleep onset latency time, and number of night awakenings were assessed prior to and during the treatment period. Children who received melatonin were found to sleep for an average of 21 minutes longer, with a 28 minute reduction in sleep latency time and a 42 minute earlier sleep onset time compared to those who received a placebo. Dr Jones remarked that treatment with melatonin can benefit children of any age. Your child's pediatrician should be consulted before initiating melatonin as a treatment for insomnia. —D Dye Review finds nuts, vegetables and Mediterranean diet associated with lower heart disease riskA review of 189 studies published in the April 13, 2009 issue of the journal Archives of Internal Medicine identified a Mediterranean diet pattern, as well as vegetables and nuts, as protective against coronary heart disease. The Mediterranean diet is characterized by a high intake of vegetables, legumes, fruits, nuts, whole grains, cheese or yogurt, fish, and monounsaturated fats relative to saturated fatty acids, and has been associated with heart disease protection in a number of studies. Andrew Mente, PhD, of the Population Health Research Institute and his associates selected 43 randomized controlled trials and 146 prospective cohort studies concerning the effect of diet on coronary or ischemic heart disease and fatal or nonfatal heart attack for their review. Pooled analysis of the data revealed a protective effect for vegetables, nuts, monounsaturated fatty acids, and Mediterranean and high-quality dietary patterns, as well as harmful effects for trans–fatty acids, high glycemic index foods, and a western dietary pattern. A modest protective effect was observed for fish, omega-3 fatty acids, folate, whole grains, alcohol, fruits, fiber, vitamins E and C, and beta-carotene. "The relationship between dietary factors and coronary heart disease has been a major focus of health research for almost half a century," the authors write in their introduction, yet they add that "the strength of the evidence supporting valid associations has not been evaluated systematically in a single investigation." "Although investigations of dietary components may help to shed light on mechanisms behind the benefits of dietary patterns, it is unlikely that modifying the intake of a few nutrients or foods would substantially influence coronary outcomes," they conclude. "Our findings support the strategy of investigating dietary patterns in cohort studies and randomized controlled trials for common and complex chronic diseases such as coronary heart disease." —D Dye Soy isoflavones improve menopausal syndromes in animal modelAn article published online on April 9, 2009 in the journal Nutrition & Metabolism reported the finding of researchers at National Chiayi University in Taiwan that soy aglycons of isoflavone (SAI) help improve some of the syndromes associated with menopause in a rat model. According to background information provided in the article, "Among the molecules of soy isoflavones, aglycon forms of genistein and daidzein are absorbed faster by humans and in higher amounts than their glucosides." The researchers hope that soy supplementation could provide an alternative to hormone replacement therapy. Robin Chiou and colleagues tested the effects of the compounds on rats whose ovaries had been removed in order to imitate the process that occurs during menopause in humans when estrogen production drops. Ten rats received diets enhanced with a low amount of SAI, 10 received a high amount, and 10 received control diets for three months. Ten rats that were given sham operations were additionally provided with control diets. While ovariectomized rats had higher cholesterol levels than those that received sham surgeries, rats received the high SAI diet experienced a reduction in total and LDL cholesterol and an increase in HDL cholesterol to levels that exceeded those of the animals with intact ovaries. The antioxidant enzyme catalase was higher in the livers of animals that received the SAI compared to the controls, and oxidative stress was reduced. The degeneration of the vaginal lining that occurred in the ovariectomized rats was improved among animals that received SAI. "These ovariectomized animals are a good model for study of the menopause as the loss of estrogen from the ovaries mimics the natural reduction in estrogen seen in menopausal women," commented Dr Chiou. "SAI itself has weak estrogenic properties and we've shown here that menopause-related syndromes can be prevented or improved by dietary supplementation with the compounds it contains." —D Dye Flushing not necessary for niacin benefitsIn an article published online on April 6, 2009 in The Journal of Clinical Investigation, researchers from Duke University Medical Center report that the flushing elicited by the B vitamin niacin is caused by a separate pathway than the one responsible for niacin's cardiovascular benefits. Niacin, or vitamin B3, can help lower triglycerides, fatty acids, and low density lipoprotein (LDL) cholesterol, while elevating high density lipoprotein cholesterol, however, some individuals cannot tolerate the flushing associated with niacin supplementation. The current finding could spark renewed interest in niacin as an inexpensive and relatively safe means of managing cholesterol. Dermatologist Robert Walters, MD, along with Howard Hughes Medical Institute investigator Robert Lefkowitz, MD and associates conducted a series of experiments to explore niacin's pathways in the body. Although it had been known that niacin initially activates the G protein coupled receptor GP109A which activates other proteins, the researchers discovered that one of these activated proteins, a member of the beta-arrestin group known as beta-arrestin1, triggers the reaction that leads to flushing. "Niacin stimulates production of a vasodilator that dramatically increases blood flow to the face, causing the flush and the hot, prickly sensation – and beta-arrestin1 is the culprit that enables that to happen," Dr Walters explained. "Interestingly, however, beta-arrestin1 plays no role whatsoever in niacin's ability to lower cholesterol and fatty acids. The G proteins do that." The finding could lead to the development of a drug that would activate GP109A without triggering beta-arrestins. "This opens up whole new realms for drug discovery," Dr Walters remarked. "Not only could it lead to new niacin-based therapies for cholesterol that patients could actually stick with, but it could also mean new treatments for flushing that comes with some types of allergic reactions, hives and other disorders." —D Dye Positive health behaviors improve head and neck cancer survivalIn an article published online on March 16, 2009 in the Journal of Clinical Oncology, University of Michigan School of Nursing associate professor Sonia Duffy, PhD, RN and her associates reveal that head and neck cancer patients who engaged in four healthy habits before being diagnosed with the disease lived longer than those who did not practice these behaviors. The current study included 504 patients who took part in the University of Michigan Head and Neck Cancer Specialized Program of Research Excellence (SPORE ) prospective cohort study. Participants were periodically surveyed over up to five and a half years of follow-up concerning their smoking status, alcohol intake, exercise habits, diet, physical activity level, and sleep habits. During this time, 166 deaths occurred. Smoking had the greatest negative impact on survival, with current smokers and former smokers experiencing double the risk of dying compared to nonsmokers. Excessive drinking, low fruit intake, and poor physical activity levels were also associated with reduced survival, however, controlling for other factors reduced these risks. Sleep and vegetable intake were not found to be linked to mortality. "While there has been a recent emphasis on biomarkers and genes that might be linked to cancer survival, the health habits a person has at diagnosis play a major role in his or her survival," Dr Duffy observed. "Health behaviors are only sporadically addressed in busy oncology clinics where the major focus is on surgery, chemotherapy or radiation. Addressing health behaviors may enhance the survival advantage offered by these treatments." "Eating fruits and vegetables, not smoking and drinking in moderation can have a big impact on a person's risk of getting cancer in the first place," Dr Duffy noted. "Now it appears that these factors also impact survival after diagnosis." —D Dye Beneficial olive oil compound identifiedIn an article published online on April 2, 2009 in the journal Molecular Nutrition & Food Research, Portuguese researchers announced the identification of a known antioxidant compound in olives as the major source of the cardiovascular benefits associated with olive oil consumption. Fatima Paiva-Martins and associates at the Universidade do Porto compared the effects of varying doses of four polyphenolic olive compounds: oleuropein, hydroxytyrosol, and two oleuropein aglycones known as 3,4-DHPEA-EA and 3,4-DHPEA-EDA, on red blood cells exposed to oxidative stress via a free radical-producing compound. Oxidative stress caused by reactive oxygen, including free radicals, contributes to atherosclerosis via the oxidation of low density lipoprotein cholesterol. The high oxygen content of red blood cells renders them particularly vulnerable to damage or destruction (hemolysis) from oxidative stress. The research team found that while all of the olive oil compounds showed an ability to help protect red blood cells from oxidative injury, 3,4-DHPEA-EDA emerged as the most effective compound, even at the lowest concentration tested. Hydroxytyrosol was also significantly protective. "For the first time, it was demonstrated that 3,4-DHPEA-EDA, one of the most important olive oil polyphenols, may play a noteworthy protective role against reactive oxygen species-induced oxidative injury in human cells since lower doses of this compound were needed to protect red blood cells in vitro from oxidative mediated hemolysis," the authors conclude. "These findings provide the scientific basis for the clear health benefits that have been seen in people who have olive oil in their diet," Dr Paiva-Martins stated. "Now we have identified the importance of these compounds, producers can start to care more about the polyphenolic composition of their oils." —D Dye Protective effect of nutritional supplements evident a decade laterThe April 1, 2009 issue of the Journal of the National Cancer Institute published the outcome of research conducted by the Chinese Academy of Medical Sciences in Beijing and the National Cancer Institute in Bethesda, Maryland, which found a continued protective effect for a specific nutritional supplement combination on all cause mortality over a ten year period. The current study included participants in the General Population Nutrition Intervention Trial of 29,584 residents of Linxian, China, conducted between 1985 to 1991. This trial tested the effects of eight combinations of nine vitamin and minerals on the risk of esophageal and gastric cardia cancer, concerning which the residents of Linxian have some of the highest rates in the world. The trial found that "factor D", which included 50 micrograms selenium, 30 milligrams vitamin E and 15 milligrams beta-carotene, was associated with a reduction in all cause mortality, as well as total cancer and gastric cancer mortality. From the beginning of the trial through May, 2001, 9,727 deaths occurred, including 3,242 from cancer, 1,515 from esophageal cancer, and 1,199 from gastric cancer. Subjects who received factor D had a 5 percent lower risk of dying from all causes than those who did not receive this combination. The effect was observed mainly among participants younger than 55 years. "In summary, 10 years of postintervention follow-up of participants in this cancer prevention trial demonstrated the durability of previously observed beneficial effects on mortality from supplementation with selenium, vitamin E, and beta-carotene," the authors conclude. "The persistence of risk reduction for up to 10 years after treatment in this trial reinforces the validity of the original trial findings and is consistent with an emerging new paradigm in cancer prevention, namely, that prevention may be achievable with short-term as opposed to life-long treatment." —D Dye |


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As you may recall, around this time each year I like to take a moment to remind my readers that there are still plenty of reasons to be truly thankful. And if I can say that from my perch here in the heart of the newspaper business, you can certainly come up with something.
So stop reading that blood-sucking news aggregator site for a minute and take a gander at these, this year's reasons to give thanks:
1) You're not in a homemade balloon spinning somewhere above Colorado.
2) Levi Johnston has gotten nowhere near your daughter. That you know of.
3) You didn't promise anybody you'd get a massive health care bill through the House and the Senate.
4) You haven't been arrested for breaking into your own house.
5) You haven't arrested anybody for breaking into his own house.
6) You're not the planet earth, which will either implode in 2012 in a torrent of computer-generated special effects, or be sucked into a black hole by the Large Hadron Collider sometime within the next 15 minutes.
7) You didn't decide to go for it on 4th and 2.
8) Your entire image isn't being reworked against your will, like poor Mickey Mouse, whom Disney is re-imagining as more "cantankerous and cunning" — apparently the focus groups have said that they'd prefer Mickey to be more like Dick Cheney. But don't worry, "Mickey is never going to be evil or go around killing people," said one Disney Imagineer. OK, forget what I said about Cheney.
9) You didn't win that annoying Nobel Peace Prize.
10) Your image isn't showing up willy-nilly in pictures of water droplets on lotus leaves, like Ringo Starr's is. A team researching water-repellent leaf behavior at Duke University took the high-speed images, and darn it if you can't see Ringo's little mop-toppy head right there. Add this to the list of signs that the world is ending.
11) None of your sex tapes have been made public. That you know of.
12) You're not in Richard Heene's attic.
13) You're not Ruppy, one of five beagles who South Korean scientists recently engineered to become the world's first glow-in-the-dark dogs. I imagine this makes it much harder to sneak up on people. Still, it finally offers a solution to the dire tripping-over-dogs-in-the-dark problem, and if you can get the dog to curl up close enough to you, you can read by him.
14) You didn't try to address the nation's annoying schoolchildren.
15) Perez Hilton hasn't judged your beauty pageant or scribbled all over you with a white marker.
16) You're not a drinker in Arizona, where a new law allows people to bring their guns into bars. Unfortunately, actually shooting somebody in an Arizona bar is still illegal, for the most part.
17) You don't have Nicolas Cage's financial advisor.
18) You didn't lose your finger and have it replaced with a USB drive, like a man in Finland. In his defense, it is better, stronger and faster, plus it gives a whole new definition to the phrase "pull my finger."
19) You're not running for president in Iran. Or Afghanistan. Or Iraq.
20) You weren't elected president of the United States.
21) You weren't one of the many children frightened this summer by Colorado's new ill-advised water conservation mascot, the "Running Toilet," consisting of a man with an entire actual-size toilet on his head. (Best bystander quote: "I don't think the toilet meant to scare them.") No word on whether the toilet has spent any time in Richard Heene's attic.
22) You don't work for Goldman Sachs, where executives had to scale back drastically and cut their massive bonuses to almost nothing.
What? Their bonuses and spending are as lavish as ever? Somebody should make those guys work for a newspaper.
this column appeared originally in North Shore Sunday. Peter Chianca is a managing editor for GateHouse Media New England. Follow him on Twitter at twitter.com/pchianca. To receive At Large by e-mail, write to firstname.lastname@example.com, with the subject line "SUBSCRIBE."


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I'm considering starting to do some freelance development work, but I'm really not that great on Design at this point. I definitely have a lot to learn on the Dev side, so I'll charge less. Would It be advisable/possible to hire a designer for the design work, and do the development myself? (charging less) I'm really lacking in the Business department too, so I don't know how I would work out all the money and communications and such. Advice?
do it by yourself, if you have enough time. you can learn more during the job…
Hi bryce-m,
Do you a hobby or area of interest that you could practise making a website? I would recommend that you don't do the being very green and taking on paid work unless the customer is clear how green you are and you both agree to a price or barter of services. Otherwise you can design and refine a hobby site so you have something to show and you put in reps to learning what will be needed to do 'paid work'. This will also help you determine price because you will no a little more about what does and doesn't take a lot of time.
It is important to spend some time refining your skills so you don't take advantage of someone. If you really want to learn you can expect that it will take 2 years until you are proficient enough to take on Design, XHTML, CSS and JavaScript; many people take longer than this.
It is good that you are thinking about doing this and not just jumping in before asking questions, but you want to be sure you deliver what you promise and how do you know what to promise if you haven't done it very much or at all? I don't think you can make promises with an absence of experience.
if you get the work, it never hurts to set up relations with some designers to help … the bottom line is, you want to make things happen for the client
Try to do it yourself first. At least give it a try to know the outcome. If it is worthy than hire a designer. Don't give up at any point, if you lose a client you will get a new one too. Ask people who are doing some business to help you.
Hello, you can get the freelancing project at WebsiteLancers, it is a one of the best places to hire freelance web designers and projects
Well i am here i would like to say you that you should hire a good person for hire a designer because there are many fake designers who have no idea to use the graphics or designing programs and they are doing this work so this is depends on you that you should hire a good person …
Do it yourself. To gain more experience and to express your feelings more.


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Story #80
September 1974 – Winnipeg, Canada
Although Swede Thommie Bergman was signed by the Detroit Red Wings in 1972 and his countrymen Borje Salming and Inge Hammarstrom joined the Toronto Maple Leafs one year later, Europeans in the NHL were few and far between in the early 70s. And apart from Salming, they didn't have much impact and the tough Swede was seen as an exception to the rule that said that you can't build a team around Europeans.All that changed in 1974 when the World Hockey Association started to systematically sign Europeans, mostly Swedes and Finns who were easily accessible. When the WHA was introduced in 1972, the rebel league was dominated by the New England Whalers and the Houston Aeros who only had North American players. In Winnipeg, general manager Rudy Pilous and coach Bobby Kromm realized that courting European might be the way to WHA dominance. How right they were. It started with Swedes Anders Hedberg and Ulf Nilsson joining in 1974 and the flashy Scandinavians formed one of the most exciting lines in professional hockey teaming up with legend Bobby Hull. Hedberg had 53 goals in his rookie season while Nilsson set rookie records with 94 assists and 120 points.It was during that season that the North American hockey establishment realized that players from the other side of the pond could play dominating roles. The Jets were on their way to greatness and with nine (!) Europeans – including Swedish captain Lars-Erik Sjoberg – Winnipeg won the WHA championship, the Avco Cup, the next season. The 1974-75 was a milestone season for European migration to North America. The WHA would only live for three more seasons before it merged with the NHL, but the Euro-stocked Jets won in two out of the three years.The WHA and the Winnipeg Jets had immense influence on the future of pro hockey in Canada and the United States. Closely watching the free-wheeling style of the Jets, coach Glenn Sather in Edmonton started to build his upstart Oilers by emulating Winnipeg's European oriented approach. As soon as the WHA folded in 1979, the NHL raided the defunct clubs for European talent.Hedberg, Nilsson and Sjöberg joined the New York Rangers. Their cross-town rivals, the New York Islanders, won four Stanley Cups (1980-83) with four Swedish players, becoming the first NHL-club to have Europeans on their winning team. Another Swedish Jet, Willy Lindstrom, went to the Oilers and assisted Wayne Gretzky in winning Stanley Cups in the mid-80s.There is no doubt that the WHA's and the Winnipeg Jets' coveting European players in the mid-70s contributed to changing the North American game.
As part of the IIHF's 100th anniversary celebrations, www.IIHF.com is featuring the 100 top international hockey stories from the past century (1908-2008). Starting now and continuing through the 2008 IIHF World Championships in Canada, we will bring you approximately three stories a week counting down from Number 100 to Number 11.
The Final Top 10 Countdown will be one of the highlights of the IIHF's Centennial Gala Evening in Quebec City on May 17, the day prior to the Gold Medal Game of the 2008 World Championship.
These are the criteria for inclusion on this list: First, the story has to have had a considerable influence on international hockey. Second, it has to have had either a major immediate impact or a long-lasting significance on the game. Third, although it doesn't necessarily have to be about top players, the story does have to pertain to the highest level of play, notably Olympics, World Championships, and the like. The story can be about a single moment — a goal, a great save, a referee's call — or about an historic event of longer duration — a game, series, tournament, or rule change.
Click here for the 100 Top Stories


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Senate Bill 307, Let more cities impose additional public safety property tax: Passed 37 to 0 in the Senate
To allow cities with less than 70,000 residents impose "special assessment" property taxes to pay for police and fire services. These taxes would be imposed over and above regular property taxes, and require voter approval. According to the Senate Fiscal Agency, this could allow 278 cities to impose these additional taxes.
Who Voted "Yes" and Who Voted "No"
House Bill 4952, Halt unemployment benefits for failed drug test: Passed 28 to 10 in the Senate
To make a person ineligible to collect unemployment benefits if a prospective employer requires a drug test as a condition of a job offer and the individual either refuses to take the test or fails it.
Who Voted "Yes" and Who Voted "No"
Senate Bill 475, Establish trampoline court regulations & liability limits: Passed 25 to 12 in the Senate
To establish standards and regulations for trampoline courts and operators, and grant these businesses limited immunity from lawsuits if the proposed regulations are followed.
Who Voted "Yes" and Who Voted "No"
Senate Bill 277, Repeal requirement commercial trucks display owner's name: Passed 38 to 0 in the Senate
To eliminate a requirement that commercial vehicles weighing more than 5,000 pounds must display the owner's name on the cab. Wrecker trucks and road service vehicles would still be subject to the mandate.
Who Voted "Yes" and Who Voted "No"
House Bill 4866, Authorize new bicycle rider hand signals: Passed 106 to 0 in the House
To establish new signals for bicycle riders. Left turns would be indicated by extending the left arm straight out; right turns by either extending the right arm, or the left arm with forearm raised (which is the current standard), and slowing or stopping by "extending the left hand and arm downward."
Who Voted "Yes" and Who Voted "No"
Senate Bill 332, Exempt "natural fertilizer" from phosphate content restrictions: Passed 102 to 6 in the House
To exempt "natural fertilizer" from restrictions imposed by a 2010 law restricting spreading a fertilizer containing more than 0.5 percent of the plant nutrient "available phosphate" (p2o5) on a lawn, golf course or other grass.
Who Voted "Yes" and Who Voted "No"
Senate Bill 489, Revise detail of property tax imposed on business tools and equipment: Passed 82 to 26 in the House
To revise details of a 2012 law that exempts from property tax up to $80,000 ($40,000 in "taxable value") worth of tools and equipment owned or leased by a business in a particular jurisdiction. (This so-called "personal property tax" imposes annual property taxes on business tools and equipment.) The bill would empower local assessors to retroactively deny exemptions for the three past years; authorize criminal penalties for claiming the exemption on ineligible property; revise what property is eligible; impose new record-keeping requirements on businesses; and more. It and Senate Bill 490 are considered a "clean up" of provisions in that 2012 law.
Who Voted "Yes" and Who Voted "No"
House Bill 4121, Give five-year tax break to buyers of school property: Passed 62 to 44 in the House
To give owners of property purchased from a public school district a five year property tax exemption. Local tax-collecting units (including local governments, taxing authorities, taxing "districts," etc.) could opt out of providing the exemption.
Who Voted "Yes" and Who Voted "No"
SOURCE: MichiganVotes.org, a free, non-partisan website created by the Mackinac Center for Public Policy, providing concise, non-partisan, plain-English descriptions of every bill and vote in the Michigan House and Senate. Please visit https://www.michiganvotes.org.
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By Admin1 (admin) on Friday, August 29, 2003 - 10:48 am: Edit Post |
Bush meets with future PCVs in Minneapolis
"There is a legitimate philosophical difference here, and it involves the difference between voluntarism and service. Voluntarism is the act of doing valuable things that fall just outside the normal scope of governance.Read the op-ed and draw your own conclusions on where the Peace Corps falls in the big scheme of things as defined above: voluntarism or service? Does Bush really support the Peace Corps and is he willing to fight to defend his promise to double the Peace Corps by 2007 or is the Peace Corps next to be disappointed? Read the op-ed at:
Service is more intense: it is a full-time commitment to do the most difficult public works�policing, teaching, social casework. The Police Corps, which exists outside AmeriCorps, and Teach for America are exemplars of the latter.
They are unabashedly élitist; TFA accepts only 13% of all applicants. They involve rigorous training programs. And the goal is to leverage the altruism of the best and the brightest college students, putting them to work on the toughest jobs in the toughest neighborhoods�and, in the process, to help create a new generation of leaders like the "Greatest" generation, imbued with the spirit of sacrifice."
| Top Discussion Stories


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A new travel website offers visitors and residents a comprehensive resource to find unique attractions and outdoor adventures in the Tucson Mountains and Sonoran Desert.
TUCSON, AZ, November 19, 2020 /24-7PressRelease/ -- In January 2021, a new travel website, www.ExploreTucsonMountains.com, officially opens, offering visitors and residents a comprehensive resource to find unique attractions and outdoor adventures in the Tucson Mountains and Sonoran Desert.
The Tucson Mountains has a rich history of Native American culture, Spanish explorers, and western lore. Plus, it has been a picturesque western backdrop in over 400 movies and TV shows. Today, it is a popular destination for out-of-town visitors and local residents because of its attractions and a wide variety of activities for the outdoor enthusiast. This new comprehensive website enables users to quickly find fun and adventure just a short drive from downtown Tucson. The website profiles:
• Unique Attractions: AZ-Sonora Desert Museum, Saguaro National Park-West, San Xavier Mission, and many lesser-known but must-see attractions.
• Outdoor Activities: More than 150 hiking/biking trails, horseback riding, rock climbing, hunting, birding hotspots, fishing, golf, and more.
• Out of the Ordinary Adventures: Skydiving, hot air balloon rides, helicopter rides, ATV rentals, abandoned mines, Indian petroglyphs, and more.
• Food and Spirits: Steak houses, family-owned Mexican restaurants, craft breweries, and a search tool to over 50 tasty places to eat and drink.
• Catch Some Shuteye: Bed and breakfasts, resorts/hotels, dude ranches, RV/tent camping, and a search tool to over 40 West Tucson hotels.
Plus an Event Calendar, Wildlife Photo Gallery, Trail Cam Video Gallery, Historical Timeline, Movie Film Locations, Online Store, and 100+ fun activity ideas.
"This is ABSOLUTELY FANTASTIC!"
Susan S.
"Really like the trail cam videos!"
Sheryl H.
"Tons of info and easy to navigate!"
Darin G.
www.ExploreTucsonMountains.com is published by a retired reference book publisher and longtime resident of the Tucson Mountains.
Press Contacts
Mark Sankey
[email protected]
# # #


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Elton to play Edinburgh
Music legend Elton John has announced a summer open-air concert date in Edinburgh.
Sir Elton will rock Meadowbank Stadium on June 25, 2016, as part of his Wonderful Crazy Night Tour.
The concert will be the first time the pop icon has played in Edinburgh for 10 years.
Hide AdAdvertisement
Hide AdHe said: "Edinburgh has always been a very special place for me to play. I did my first truly solo show at the Playhouse back in 1976."
Tickets will be available from 10am on Friday, December 4, on 0844 847 2441, 08448 24 48 24, or online from Ticketmaster or axs


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The 'Plebgate' saga, which has now drawn apologies to Andrew Mitchell from three chief constables, has once again raised questions about police integrity and dented public trust and confidence in policing more generally. Building such trust was, of course, one of the Coalition Government's arguments for introducing Police and Crime Commissioners (PCCs) – and, as the first anniversary of those elections is now close upon us; it seems timely to consider what difference PCCs have so far made.
It was, we all remember, an inauspicious start; with an embarrassingly low electoral turn-out (averaging less than 12 per cent) because of poor advance publicity on the new PCC role; failure to provide most voters with candidate election leaflets, and choice of a November polling date when no other local or national elections were taking place. Moreover, matters seemed to get worse in subsequent months with critical media headlines concerning the appointment of deputy commissioners and youth commissioners; reports of disagreements and discord with chief constables, and discontent over policy priorities and budget decisions.
But one year on, with PCCs becoming established in their roles, the picture has begun to look rather more settled. It is, for sure, too soon to assess the impacts – beneficial and otherwise – of the new police governance framework. But a recent round of 'stock-take' interviews with a small sample of PCCs (including Conservative, Labour and Independent office holders), has highlighted at least two key respects in which the directly-elected model of governance already seems distinctly different from the previous regime of Police Authorities.
First: the new PCCs are giving much more priority to public engagement –they are out and about on a near daily basis, presenting themselves and taking feedback at council meetings, in open public meetings, and indeed, in shopping precincts and market squares around their (very large) patches. They are also all actively exploiting the potential of Facebook, Twitter and other social media in reaching-out and communicating and handling considerably more direct correspondence (email and post) and telephone calls from citizens. Their public profile is already much higher than that of Police Authorities.
Second: there is a stronger sense of 'local leadership' to their work. The Home Office has admirably resisted the temptation to try to drive the new system and impose its own perspectives and priorities on PCCs. Although cuts in all police budgets have been driven by reductions in Home Office grants, Westminster and Whitehall have generally allowed PCCs to get on with the job locally as each considers best. As a result, there is more diversity between the PCCs with regard to their approach and priorities in the role than was previously apparent with Police Authorities.
Relationships and accountabilities with chief constables and with other criminal justice and local governance agencies are intriguingly variable, as each PCC brings their own personality and preferred style to the role. Indeed,it is clear that the different career backgrounds and experiences of each PCC are colouring and shaping their approach to the role and their priorities.
By the time of the next PCC elections – scheduled for May 2016 – it will be interesting to gauge the significance and durability of these early signs of change towards stronger democratic engagement and local accountability, and to see what, if any, are the implications for public trust and confidence in policing. At least a more lively public debate and much higher turn-out are surely to be expected next time.
Professor John Raine
Professor of Management in Criminal Justice


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Where Does Christian Living Come From?
It is remarkable that again and again the apostle Paul confronts failure to do what's right with failure to know what's right. For example:
Right Knowing Prevents Continuing in Sin.
Are we to continue in sin that grace might increase? May it never be! ... or do you not know that all of us who have been baptized into Christ Jesus have been baptized into His death? (Romans 6:1-3)
Right Knowing Prevents the Prostituting of Grace.
Shall we sin because we are not under law but under grace? May it never be! Do you not know that when you present yourselves to someone as slaves for obedience, you are slaves of the one whom you obey, either of sin resulting in death, or of obedience resulting in righteousness? (Romans 6:15-16)
Right Knowing Prevents Boasting.
Your boasting is not good. Do you not know that a little leaven leavens the whole lump of dough? (1 Corinthians 5:6)
Right Knowing Empowers Good Dispute Settling.
Or do you not know that the saints will judge the world? And if the world is judged by you, are you not competent to constitute the smallest law courts? Do you not know that we shall judge angels? How much more, matters of this life? (1 Corinthians 6:2)
Right Knowing Prevents Fornication.
Do you not know that your bodies are members of Christ? Shall I then take away the members of Christ and make them members of a harlot? May it never be! Or do you not know that the one who joins himself to a harlot is one body with her? For he says, "The two will become one flesh." … do you not know that your body is a temple of the Holy Spirit who is in you, who you have from God, and that you are not your own? (1 Corinthians 6:15-19)
Paul is simply continuing the emphasis of Jesus who said, "You will know the truth and the truth will set you free" (John 8:32). "Sanctify them in the truth; your word is truth" (John 17:17).
Therefore don't coast in your thinking. Don't be passive with your mind. Instead…
Make your ear attentive to wisdom,
Incline our heart to understanding;
Cry for discernment,
Lift your voice for understanding;
Seek her as silver,
And search for her as for hidden treasures
(Proverbs 2:2-4)
In quest of life-changing truth with you,
Pastor John


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A bow-tied slipper
Embroidered ribbons as a decorative motif are ever present at the Musee Carnavalet.
The Marie-Antoinette exhibit at the Grand Palais is what made me sit up and take notice of French ribbon - this hairdo guide at the show. I'm reading the unputdownable Antonia Fraser biography of Marie-Antoinette
Ribbons were not just decorative touches - they held hats on or used as belts - they were the zipper of their day.
The ribbon as painted decor on a wall - does anyone do it better here at Chateau Vaux le Vicomte.
And here in an old boulangerie in the 18th wall ribbons keep croissants safe from greedy fingers.
Here a do-it-yourself wall treatment to buy at department store BHV.
So when I saw this box of John & Kira's chocolates decked out in wired French ribbon I had to get it and paint it. The chocolates inside are flavored with lavender, ginger, bergamot and lemongrass


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270 W. Pearl Avenue Unit 109
Closed 12/16/2020. Sale Price $172,779
**Important! To apply for this home, you must have completed the Online Intake Form prior to September 16, 2020. Please do not make any changes to your essential data during the weighted drawing period or you will not be eligible to apply.**
270 W. Pearl Avenue, Unit 109:
- Studio, 1-bathroom, range, refrigerator, microwave, dishwasher, 367 square feet, 60 square foot storage unit.
- Home price - $172,779
- Household income must be between 80% to 120% of the median family income (details below)
- Household size must be one (1) or two (2) people
- 1 household pet
- Shared entrance with only 2 other units
- Laundry on site, shared with 2 other units
- Permanent Parking Pass for Town Parking Garage
- At least one adult in the household must work a minimum of 1,560 hours per year. Please read the policies to enter any weighted drawing: Housing Department Rules & Regulations, Section 4: Weighted Drawing.
- Deadline to Apply: Tuesday September 29th by 4:00 p.m. No late or incomplete entries will be allowed, no exceptions. If selected first for this unit you will be notified by phone. All others will be sent an email notice.
- All forms needed to enter into this weighted drawing are here, under "Ownership - Weighted Drawing Entry Forms". These include a completed Lender's Qualification Worksheet, current credit report, completed Home Buyer Education Class certificate, Weighted Drawing Entry sheet, and current and past work affidavits.
Income Limits: To be eligible to enter this drawing your household's gross income (before taxes) must fit into the range listed below, and your household's net assets musts not exceed the asset limit listed below.
- One person household: $61,993-$92,988
- Two person household: $70,849-$106,272
- Net asset limit: $265,680
Calculation of income:
Household income is based on the current income earned by all intended adult occupants of the Restricted Housing Unit at time of weighted drawing entry using the current household income to estimate an annual (12 month) income basis. Households must use their current income and may not make changes or adjustments during a drawing period.
Business income of a qualifying Household is calculated using an average of the last three (3) years of income on the business' tax returns. A year to date profit and loss determination will also be used to calculate business income. If the business has not been operating for three (3) years, the Housing Department will average income over the time the business has been operating.
Deadline to Apply: Tuesday September 29th by 4:00 p.m. No late or incomplete entries will be allowed, no exceptions. All forms need to enter into this weighted drawing are here, under "Ownership - Weighted Drawing Entry Forms".
You may receive one additional entry into the drawing for every year of verified full-time employment (minimum of 1,560 hours) in Teton County, Wyoming with a maximum of 10 years/entries.
Please click here for information for Critical Service Providers (CSPs).
We understand that our applications to enter into the weighted drawing take time and effort, and we do not want to disqualify you due to an oversight or misunderstanding about our process. Please bring your applications in prior to the due date so that we have time to work with you, make corrections, and give feedback if anything is wrong.
Example costs break down for a purchase price of $172,779
3.5% down payment (required) | $6,047 |
Loan Amount | $166,732 |
Principal & Interest Payment (estimated 5%) | $895 |
Property Tax (estimate) | $82 |
Insurance (estimate) | $50 |
HOA dues & monthly Ground Lease Fee (estimate) | $115 |
Total Estimated Monthly Payment | $1,142 |
Please talk to a local lender about closing costs, interest rates, and available loan programs to suit your financing needs. We recommend you choose a local lender.


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How a Liver Fluke Causes Cancer
In Southeast Asia, an all-too-common parasite is known to increase the incidence of bile duct cancer in infected individuals. A paper just released in PLoS Pathogens shows how this happens. Knowing the molecular pathway that leads from parasite infection to cancer will almost certainly speed up the search for a cure for this cancer, and will probably add to our understanding of cancer in general.
Cancer is, of course, a category of diseases rather than a single disease. What holds cancer together as a coherent set of conditions is the inappropriate increase of cell proliferation in some tissue or another. Cell proliferation is, of course, normal and expected at some times and places. When an organism is growing there is quite a bit of proliferation. When a wound is healing, cell division must be sped up. Therefore, mechanisms have evolved to increase the rate of cell division, and many cancers are simply this mechanism operating in an inappropriate and sometimes out of control way.
The cause of inappropriate cell proliferation can be a genetic mutation, caused in turn by the chance mutation of an already susceptible gene, or by some kind of chemical or physical irritant.
Or it can be a fluke.
A fluke is a kind of worm in the class Trematoda. There are about 20,000 species of Trematoda, and many of them are parasites that live in mollusks and vertebrates. Commonly, Trematoda spend part of their life cycle in a mollusk, then move to a vertebrate host, and then move back to the mollusk host, as they reproduce alternatively using asexual and sexual mechanisms.
Opisthorchis viverrini, also known as the Southeast Asian or Oriental liver fluke, lives in a certain genus of freshwater snails and in humans, and when it lives in humans, it seems to predispose the humans to cholangiocarcinoma, which is cancer of the bile ducts.
The research reported yesterday identified a certain protein that is very similar to a human growth hormone, but that is found in and produced by the fluke.
Scientists knew that a particular protein of a type known as granulin was produced by the fluke, and it was known that other versions of granulin cause unchecked proliferation of cells. So they isolated the gene for the fluke version of the granulin, and placed the gene in bacteria which allows the production of sufficient quantities of the protein to use in experiments. This, in turn, allowed them to test the hypothesis that this fluke-produced protein acts like other granulin molecules in causing cancer-like growth of cells.
It turns out that fluke produced granulin is an effective cancer-causing agent.
The fluke appears to use the granulin to induce cell growth for its own nutrient supply. In addition, the fluke-produced granulin induces specific antibodies in the host that neutralize the granulin. So, there seems to be something of an arms race between parasite (fluke) and host (human).
Now that the protein is both characterized and linked to the cancer, it may be possible to produce a drug that will fight it, or to refocus efforts on the fluke infection itself to reduce the prevalence of this cancer. Also, the Opisthorchis viverrini system may now serve as a useful model for the study of growth hormone induced cancers.
Another reason that this research is very important is that there were two very strong hypotheses for the prevalence of this cancer in southeast Asia. The fluke could have caused the cancer by simply irritating the cells where the fluke lives. Alternatively, the people in regions where this fluke are common also have a diet high in a particular chemical compound called nitrosamines, abundant in the fermented fish eaten in the region, and thought to be possibly cancer-causing. While this research does not rule those ideas out, it does strongly suggest that fluke-excreted granulin is the culprit that should be addressed first.
This research is published in an OpenAccess journal, so you can read the original by clicking here.