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Now that things are beginning to settle down a bit, and the major players on both sides of the aisle in both Houses are becoming known quantities instead of ōpotential candidatesö, lets take a look at what is in store for us over the coming two years.
ItÆs easy to make dire predictions, run around in circles flapping our wings and shouting ōthe sky is falling.ö For partisan Democrats and the liberal crowd out there, the new Congress is like a ray of sunshine after six years of night. For partisan Republicans, it must seem like the country has been consigned to outer darkness. For conservatives, well, who knows what conservatives think. Some are horrified. Some are smug; ōthatÆs what you Republicans get for not being conservative enoughö. Some see it as a chance to regroup and get back to ōtrueö conservative values. Conservatives are all over the map.
Certainly, the direction from Congress will be very different over the next two years. The biggest difference will be that Congress will have a direction, albeit one that is quite different from what most conservatives would like. This as opposed to the outgoing Republican Congress which wandered aimlessly tugged 15 directions at once by a President who, with the single exception of the war on terror, couldnÆt seem to focus on a any issue for very long, and who clearly doesnÆt share the conservative values that his party supposedly represents.
Meanwhile, the Democrats are focused. They have agenda items they have been waiting a long time to pursue. Some of these are the same items that Republicans tried to pursue; income tax reform, social security reform, and education reform to name a few. But while the names remain the same, the Democrat versions of these issues are vastly different from what conservatives would like to see enacted.
Will the President stand tall for conservative values when the Democrat versions of these initiatives come to his desk for his signature, or will he sign them so that he can take credit for being the president who passed Social Security reform, income tax reform, or Medicare reform?
History lauds President Clinton as the president who fixed Welfare, ignoring that he had to be dragged to the table to sign it, kicking and screaming, by a Republican congress. Will Mr. Bush, in the twilight of his career as president, be any different?
Judging by past history, and by Mr. BushÆs past actions in particular, I would have to say that the Democrat congress will probably be fairly successful in passing much of what they want. Oh there will be compromises, to be sure ¢ thatÆs politics. Still, if the Democrats show the velvet glove and at least appear to be willing to work with the Republicans, the Republicans will come off as cry babies if they oppose too strenuously what the press is sure to spin as a ōmandateö for change.
And of course, there is still always the ōiron fistö of investigation and impeachment that can be played if necessary.
For every Democrat chairing every committee in the upcoming 110th congress, there is a main agenda item. Senator Barbara Boxer, the incoming chair of the Senate Environment and Public Works committee is no exception. Her main catch phrases are ōglobal warmingö and ōextensive hearingsö, the latter which she shares with the majority of her Democrat counterparts. I expect the next two years will be filled with ōextensive hearingsö on all sorts of topics.
Expect a very different focus from the Senate Environment and Public Works committee under Senator Boxer. Unlike the outgoing chair, Senator Inhofe, Senator Boxer is a big proponent of the global warming theory that says human activity, particularly the burning of fossil fuels, is responsible for increasing global temperatures and if unchecked will lead to irreversible global catastrophe in just a few years. While Senator Inhofe regards it as ōthe greatest hoax ever perpetrated on the American peopleö, Senator Boxer plans, when she takes office in January, to begin ōa very long process of extensive hearingsö on global warming.
Her plans? "I think there ought to be a global-warming bill that looks at all the contributors to carbon-dioxide emissions," she said, citing California's legislation requiring automakers to reduce emissions as "an excellent role model."
An avowed liberal environmental activist, Senator Boxer is sure to take a much more aggressive stance on environmental issues than her predecessor. Her main issues seem to be concern for drinking water and oil production. She led the fight in 2003 and again in 2005 to block oil drilling in the ANWR. She also opposes drilling off shore in California.
Energy independence from foreign sources may be an important strategic consideration for the United States, but for Ms. Boxer, increasing domestic production by drilling new wells is not the way to fix the problem.
As for clean water, I have to admit, itÆs difficult to argue against. Who doesnÆt want clean water? I myself have a reverse osmosis set up at home to ensure my water is pure. Mostly it is there to take the salt out of the water that my water softener puts in. I also find it useful, however, to take out the fluoride that our city government has found it necessary to add to our water supply. I suspect that this is a use that Ms. Boxer would find objectionable.
For things that Senator Boxer deems to be a ōpollutantö however, no amount is too small to be removed, even if it is less than what may naturally occur in the water supply. Requiring businesses to do so places an undo burden on their competitiveness in the world marketplace, and increases costs to the consumer for dubious benefit.
Having said that, I am not against everything Ms. Boxer has done. She was a leader in the effort to ban methyl tertiary butyl ether (MBTE), a toxic gasoline additive that has contaminated drinking water across the country. The full effect of MBTE on humans is not known. Animal research suggest a potential cancer risk, however studies were done in inhalation not ingestation of the substance. According to the EPA, MBTE dissolves easily in water and does not ōclingö to soils very will, migrating faster and farther in the ground than other gasoline components. This makes it more likely to contaminate public water systems and private drinking water wells. It does not degrade easily in the environment and is difficult and costly to remove from ground water.
Why do we have MBTE in our gasoline? MTBE is an oxygenator. It was originally produced as a gasoline additive to replace lead as an anti-knock compound. Since 1992, MTBE has been used at higher concentrations in some gasoline to fulfill the oxygenate requirements set by Congress in the 1990 Clean Air Act Amendments, which required the use of oxygenated gasoline in areas with unhealthy levels of air pollution. Some areas used ethanol to fulfill this requirement, others, MTBE.
So MTBE was put into wide usage to fulfill a congressional requirement to combat air pollution. Sometimes it seems, the cure is as bad as or worse than the disease.
So where does Senator Boxer stand on other issues?
Interestingly, Senator Boxer received a 71% rating in support of the interests of the group Comprehensive US Sustainable Population, which has as one of its goals ōto raise public awareness that many higher costs, inconveniences and hardships, inequities, and lowered quality of life and standard of living are due to people longages (sic) more than to resource shortagesö. In other words, we have too many people in the US, and need to reduce our population to ōsustainableö levels. They would like to see US population back to where it was in the 1940s (132-150 million ¢ US Census figures).
During the same period, however she received a 9% rating from US Border Control and a 0% rating from the Federation for American Immigration Reform (FAIR), groups dedicated to ending illegal immigration into the United States. In particular, FAIR ōbelieves that the U.S. can and must have an immigration policy that is non-discriminatory and designed to serve the environmental, economic, and social needs of our countryö. Despite the avowed environmental interest expressed by FAIR, Ms. Boxer apparently supports no legislation that FAIR deems important.
It would seem that while Ms. Boxer may think we have too many people in the US, the problem is indigenous baby production, not the external surplus crossing our borders illegally. To bolster this thesis, her ratings with Planned Parenthood and NARAL Pro-Choice America are 100%, while her rating with National Right to Life Committee is 0%.
What do I expect to see come out of her committee in the next two years? Lots of investigation into global warming, along with associated legislation to curb ōgreenhouse gasö emissions across the board, but specifically targeting the automobile industry; most probably modeled on existing legislation in California. Such legislation would not be limited to cars, but include trucks and vans as well.
I would expect a whole host of federally-mandated ōtweaksö designed to increase energy conservation, such as requiring micro-CHP systems in businesses and homes, radiant barrier roof decking, solar hot water systems, etc. Some of these I might actually support, although in general, I prefer the ōcarrotö, rather than the ōbig stickö approach to government intervention. Tax incentives, such as those that expired under President Reagan, to encourage the voluntary adoption of these technologies would be a much better approach in my opinion,
However, as I have said before, we are in desperate need of a national energy policy. The Republicans donÆt appear to have any specific plans, except drilling for more oil in the ANWR. ThatÆs fine, and I agree with that; but itÆs clearly a non-starter now. And we need a much more comprehensive plan than that. Perhaps we can pick up part of the conservation piece of the puzzle here. Although I disagree in general with the idea that tax policy should be used as an engine of social change, since we are currently playing that gameģ
I would also not be surprised to see restrictions and regulations on the location of windmill farms. This seems to be becoming an issue with environmentalists who are concerned that birds are being killed, and by those who consider such to be an eyesore.
In short, we should see a very different direction taken by the Senate Environment and Public Works committee than has been the case for the past four years. How much legislation will actually pass depends on whether or not Mr. Bush can find his veto pen, and where the legislation is attached. Should the Democrats hold the Senate in 2008, and take the Presidency as well, I expect you will see this committee become more of a factor in your everyday life than ever before.
Previous Global Warming and Energy related articles by this author:


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TK Adventure RPG
Three Kingdoms adventure role-playing 2.5D Vertical game based on a true story
EZ Helicopter
Drive a simple helicopter to resist the alien invasion. Collect coins to upgrade your helicopter. and recapture as much human land as possible
WuXia Metaverse
Practice a hundred thousand martial arts. and use that courage to face the dangers of the universe..

subset: commoncrawl


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Introduce una URL
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This 22-year-old girl has a 27-year-old fiancé whom she has been with for 6 years. Her fiancé also happens to be the very first guy that she has ever dated, and she really doesn't know what her life would be like without him.
She always looked at him as her entire world, and their relationship really hasn't been all rainbows and roses.
Both her family and his family are incredibly harsh, and that has really caused them to struggle. On top of all of that, her fiancé's mom is someone she really resents, and this woman has really made her life miserable.
They were able to overcome so many difficulties in their time together, specifically caused by family members, and a little under a year ago, her fiancé proposed to her.
"I've had my doubts and concerns over the years, but I could never get myself to let go because it felt like I'd die without this person, and the more the family tried to separate us, the more we wanted to stay together, as if of stubbornness," she explained.
"Now, after all this time, our families are on board, and we've spent 10s of thousand of dollars on the wedding down payments and my dress. As I've mentioned, I definitely had doubts but just tried to ignore them. However, recently I started getting this deadly feeling in my gut like something isn't right. I couldn't sleep, eat, or move, and it all related back to the idea of us getting married."
"Whenever anyone mentions anything related to me getting married, I don't get happy and excited. Instead, I want to dig a hole and hide in it forever. What makes all of this 100x worse is that my partner is overall a great person, loving, caring, generous, and for the most part, understanding. He is 100% committed to the idea of us getting married. He doesn't deserve this, but do I deserve to live with these feelings?"
She honestly believes that she has "outgrown" her fiancé, and he can't see this at all. She doesn't see how she and her fiancé have any similarities anymore.
For example, she adores working out, yet her fiancé won't even try to enjoy this activity with her. She has attempted many times to get him into working out with her, but he never took her up on that.
Sign up for Chip Chick's newsletter and get stories like this delivered to your inbox.


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Free Casino Slots Party at the Community College District
It would be very difficult for someone who isn't familiar with the game of gambling to choose from the hundreds of available. Casino gaming is extremely complicated. It is also very easy for players to lose money when playing. It is easy to lose money when playing. This is why it's crucial that players know which games are worth their effort and which ones aren't.
The staff at the casino set up the slot machine and gives it an undetermined name to help players get familiar with the game's mechanics. The machine is then placed before everyone, with the words "starting jackpot" appearing on the screen. If the player says "loosen up", the slot won't spin. Only a tiny fraction of a% of people that enter the casino actually get the jackpot.
There are numerous other ways people can learn about the basics of online casinos. One of these is to read online reviews about slot machines. Search engines like Google and Yahoo for reviews of slot machines. They can save a great review and revisit it later, if they discover it.
You may also like playing online slots for free in your spare time. Casino games online can be played while people are at school or at work. They can play these no-cost casino games between all of those things so they don't have to worry about being absent from their routine.
However, it is possible for players to win real money from online free spots. Casinos offer bonus offers every now and then. These bonuses can have more value than a person could win at an ordinary slot machine. A player can sometimes get lucky enough to win real cash when playing free online slot machines.
When looking for a progressive jackpot game the first thing that a player should be focusing on is the reels. The machines typically have four reels. Sometimes there may be five reels on the machine. Each reel can be worth a specific amount of money. The player must be on the lookout for the reels that have the jackpot. If this occurs, the player must stop playing and try to beat it.
There are certain reels that slots games can only use. These are the reels with the top middle, bottom, and middle of the cage. These are the places where the biggest jackpots are located. One good option is to try and make bets on progressive slots with the top or bottom most jackpots. This is because if someone wins on one these machines, they might be able to walk away from the casino with a huge jackpot.
Promotional free slots are more popular. This means that these machines will be more likely to pay a lot of money when they do win the jackpot. In some instances one can increase their winnings by playing only few games. This makes the slot machines with promotions the most suitable places to play for fun casino games.
The best way to earn free money from slots at an online casino is to take a few coins. This is because when a machine hits a jackpot , it will add a lot of money to the bets that people make on the machine. But, many don't know how to do this correctly. The result is that they are left with more coins than they actually have.
This is where the free slots are played within the district of community colleges. The game of slots here is beneficial because it gives people the chance to learn to use a machine in the proper way. Many community colleges offer multiple slot machines for players to pick from. This allows people to choose from a range of machines for a less cost. Some community colleges offer no deposit bonuses for those who play in their casinos.
Slot machine games for free are fantastic because they offer players the chance to learn the game without spending any money. This allows them to improve their skills and hopefully win the jackpot at the end of the day. This is one of the most effective casinos with neteller ways to do this. Find out where the best slot spinners are in your region and then start spinning.


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First of all, thank you so much for allowing us to assist you with your packaging solutions!
Now that your products are ready to go and we would love to hear all about it. And, with your permission, we'd like to share your testimonial with our other clients.
Release for use of testimonial, photos and/or video:


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Kaboodle Designer-Look Kitchens
Kaboodle believes that every Australian deserves great value, designer-look kitchens that reflects their personal style. That's why they developed a DIY-friendly range focused on design, quality, style and functionality.
While they specialise in kitchens, their large range of cabinetry, benchtops, handles, hardware and functional storage accessories are often used throughout home offices, wardrobes, laundries and more Australia-wide, providing versatile whole of home joinery solutions.
kaboodle kitchen is an Australian owned business with family owned manufacturing facilities located in Australia, New Zealand and abroad. Its purpose-built facility in Somerton, VIC utilises leading state of the art machinery to facilitate all bespoke, cut to measure request orders on a national scale.
To virtually tour their impressive facility, VISIT HERE.
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As a testament to the quality and durability of their products, kaboodle offers a 10-year warranty on all cabinets, hinges, drawer runners, handles, doors, panels and laminate benchtops. They also offer the 'Kaboodle Lifetime Advantage' which means that kaboodle provides a lifetime structural warranty on cabinet carcasses installed, for the entire time you own and live in the property!
As one of Australia's largest national suppliers of kitchen cabinetry, kaboodle is conscious of their environmental impact. Some of their efforts include:
- Working towards 100% sustainable packaging with all cabinet packaging now made from honeycomb cardboard
- Its Australian manufacturing facility uses 50% recycled cardboard to package kaboodle kitchens
- White vinyl manufacturing offcuts are re-purposed with industry partners
- Re-using pallets: when damaged pallets are returned, they are repaired and returned into circulation, reducing waste in the purchase of new pallets
Kaboodle also offer a design blog on their website, which is full of inspiration including designer tips and trends from across the globe.
For more information on working with kaboodle:


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The Surfrider Foundation's 2022 Clean Water Report was released last week, and it was shocking to have Hawaii make the three most polluted popular beaches in the nation. Ugg. Their report is attached below.
Clearly, in Hawaii and across the country, we all love beaches. Surfrider says that over 100 million of us flock to beaches yearly for recreation and leisure.
We often think of Hawaii as having pristine, clear turquoise water, and to be honest that's true a great deal of the time. And we love it! But sometimes, that isn't the case. Hawaii's three shockingly polluted beaches include those below. And it isn't just those three beaches.
Nawiliwili Stream/Kalapaki Beach Park, Kauai (pictured).
In our lead photo, this beach is polluted 100% of the time. Were it not for the continuous pollution, Kalapaki Beach would be considered excellent for swimming, surfing, and more. It sits in front of the Royal Sonesta Kauai, previously the Kauai Marriott Beach Resort. The beach is in part protected from large surf by a break wall.
The problem here is the polluted Nawiliwili Stream that flows across the sand and into Kalapaki Bay. While Surfrider has tested it, the state health department does not test here because the stream is not considered part of the marine beach. Surfrider reports that Nawiliwili Stream has not measured a bacterial count below the state health standard since 2016.
Kahaluu Beach, Oahu.
Not to be confused with Kahaluu Beach on Big Island, where snorkeling is popular, Kahaluu on Oahu is reportedly polluted 88% of the time. It is on the windward (east) side of Oahu, located along Kaneohe Bay, not far from Kailua, and just north of Kaneohe. In Hawaiian, ka haluʻu is defined as the "diving place." Perhaps now it's better to enjoy the view.
Kahaluu is used to access Kaneohe Bay to go snorkeling, boating, and fishing. The watershed has a high concentration of cesspools. Kahaluu is at the receiving end of a stream that brings stormwater down to the beach.
Hanamaulu Beach, Kauai.
Surfrider reports that Hanamaulu Beach is polluted 80% of the time. With calm water in the bay, pollution washes from the stream into the ocean. There's no lifeguard at Hanamaualu Beach Park. Hanamaulu is the ancient birthplace of Kawelo, one of Kauai's ruling families.
This county beach park has many recreational uses, including traditional Hawaiian fishing practices. There is a stream next to the park that empties into Hanamaulu Bay. It's tested high every time over the past decade.
Surfrider collected more than 9,000 water samples.
Surfrider tests ocean water for bacteria levels to raise awareness of beach and ocean health and to help find solutions to pollution.
"The Surfrider Foundation was founded in 1984; improving coastal water quality has been one of our
top priorities. Through our Clean Water Initiative, we strive to protect water quality and reduce pollution so it is safe to surf, swim and play in the ocean and in our coastal waterways."
What is the cause of Hawaii's beach pollution?
More than anything else, the cause of pollution in Hawaii's ocean water is antiquated cesspools. Hawaii still has 88,000 of these, some of which are scheduled to be around until 2050.
The cesspools contribute more than 50 million gallons of raw sewage daily into the state's groundwater and surface water. Cesspools are an old technology for disposing of untreated wastewater. The impacts of the pollution include groundwater, that's responsible for the vast majority of Hawaii's drinking water. It also puts residents and visitors at risk of illness and seriously harms streams, the ocean, and our coral reefs.
In 2017, the Hawaii Legislature passed Act 125 to require the replacement of all cesspools by 2050. It also directed the Department of Health to prioritize the replacement of the most damaging cesspools based on their influence on public health.
The impacted beaches have streams that flow nearby. That's an important consideration before entering the ocean. What you can do is check water safety before going in.
And it's not just these three Hawaii beaches either.
For example, while Hanalei Bay Kauai did not rank in the top three, entering the ocean near the Hanalei River (around the pier) is not recommended unless the water is clear. The middle part of Hanalei Bay is fine, and we will often walk down that way if water clarity and likely pollution is an issue.


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143 results found
Demir ZA, Marczin N, 2023, ERAS in Cardiac Surgery: Wishful Thinking or Reality., Turk J Anaesthesiol Reanim, Vol: 51, Pages: 370-373, ISSN: 2667-677X
Enhanced recovery after cardiac surgery (ERACS) is a multi-disciplinary approach to improve patient outcomes and reduce complications following cardiac surgery. The aim of ERACS protocol is to optimize pre-operative preparation, reduce surgical trauma, and minimize post-operative stress.The protocol has been shown to improve patient outcomes, including shorter hospital stays, lower rates of complications, and faster return to normal activities. It is important to note that ERACS is a multi-disciplinary approach, and requires close collaboration between surgeons, anaesthesiologists, nurses, and other healthcare professionals to ensure successful implementation. Anaesthesiologists play a crucial role in the ERACS protocol, as they are responsible for the management of the patient's anaesthesia and pain management during and after surgery. In this paper provide an overview of the ERACS protocol from the perspective of an anaesthesiologist.
Sef AV, Ling CNY, Aw TC, et al., 2023, Postoperative vasoplegia in lung transplantation: incidence and relation to outcome in a single-centre retrospective study, BRITISH JOURNAL OF ANAESTHESIA, Vol: 130, Pages: 666-676, ISSN: 0007-0912
- Author Web Link
- Cite
- Citations: 2
Marczin N, de Waal EEC, Hopkins PMA, et al., 2021, International consensus recommendations for anesthetic and intensive care management of lung transplantation. An EACTAIC, SCA, ISHLT, ESOT, ESTS, and AST approved document, JOURNAL OF HEART AND LUNG TRANSPLANTATION, Vol: 40, Pages: 1327-1348, ISSN: 1053-2498
- Author Web Link
- Cite
- Citations: 12
Senturk M, El Tahan MR, Szegedi LL, et al., 2020, Thoracic Anesthesia of Patients With Suspected or Confirmed 2019 Novel Coronavirus Infection: Preliminary Recommendations for Airway Management by the European Association of Cardiothoracic Anaesthesiology Thoracic Subspecialty Committee, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, Vol: 34, Pages: 2315-2327, ISSN: 1053-0770
- Author Web Link
- Cite
- Citations: 36
Erdoes G, Vuylsteke A, Schreiber J-U, et al., 2020, European Association of Cardiothoracic Anesthesiology (EACTA) Cardiothoracic and Vascular Anesthesia Fellowship Curriculum: First Edition, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, Vol: 34, Pages: 1132-1141, ISSN: 1053-0770
- Author Web Link
- Cite
- Citations: 10
Cummings IG, Lucchese G, Garg S, et al., 2020, Ten-year improved survival in patients with multi-vessel coronary disease and poor left ventricular function following surgery: A retrospective cohort study., Int J Surg, Vol: 76, Pages: 146-152
OBJECTIVE: Patients with multi-vessel coronary artery disease and poor left ventricular (LV) function (ejection fraction [EF] < 30%) requiring revascularization are considered 'high-risk'. Limited long-term survival data exists comparing percutaneous coronary intervention (PCI) with second-generation drug-eluting stents (DES) versus surgery for this cohort of patients. METHODS: We retrospectively reviewed our data for 321 patients with EF < 30% who underwent multi-vessel revascularization from January 2005 to December 2015 using Cox regression analyses and inverse probability treatment weighted (IPTW) methods. We stratified patients that underwent surgical revascularization into on-pump coronary artery bypass grafting (CABG) and off-pump CABG and analyzed all-cause mortality at 10 years compared to PCI. RESULTS: 214 patients underwent CABG (n [on-pump CABG] = 94; n [off-pump CABG] = 120) and 107 patients had PCI with second generation DES. PCI with DES had higher 10-year mortality compared with on-pump CABG (Hazard ratio [HR] = 1.86, 95% confidence interval [CI] = 1.46-2.42; p < 0.001) and off-pump CABG (HR = 2.32, 95% CI = 1.75-3.15; p < 0.001). This was confirmed in IPTW analyses. When adjusting for both measured and unmeasured factors using instrumental variable analyses, PCI with DES had higher 10-year mortality compared with on-pump CABG (Δ = 13.5, 95% CI = 3.2-24.5; p = 0.012) and off-pump CABG (Δ = 16.1, 95% CI = 5.9-25.8; p < 0.001). CONCLUSION: Surgical revascularization, preferably off-pump CABG, results in better long-term survival compared with PCI using second generation DES for patients with multi-vessel coronary artery disease and poor left ventricular function. Randomized controlled trials in this patient group should be undertaken.
Marczin N, Romano R, Scaramuzzi M, 2020, Lung transplantation: Justification for a paradigm change, Anesthesia in Thoracic Surgery: Changes of Paradigms, Pages: 277-287, ISBN: 9783030285272
Although lung transplantation (LTx) has moved from experimental surgical options to established therapy with increasing worldwide activity, growing recipient waiting lists and improving outcomes, it remains limited by donor shortages, high perioperative morbidity and mortality and the lowest long-term survival of all solid organ transplants. Unfortunately, development of severe Primary Graft Dysfunction (PGD) remains too prevalent and nonpulmonary complications are nearly ubiquitous with both negatively effecting long term patient survival and quality of life. Such analysis highlights the need for anaesthesia and intensive care to take better ownership of the total morbidity burden and perioperative and consequent long-term mortality. It also calls for constant quality improvement and ongoing critical appraisal of our management goals to understand better and to exploit new opportunities to reduce complications, enhance perioperative patient journey and ultimately to improve both short- and long-term survival of lung transplant recipients. This chapter provides insights into the major paradigm shifts in our anaesthesia mission and regarding some of the principle intraoperative and postoperative management strategies. These are underpinned with exciting new basic research progress regarding the leukocyte theory and cytokine concepts of acute lung injury in the setting of LTx.
Kiss T, Wittenstein J, Becker C, et al., 2019, Protective ventilation with high versus low positive end-expiratory pressure during one-lung ventilation for thoracic surgery (PROTHOR): study protocol for a randomized controlled trial (vol 20, 213, 2019), TRIALS, Vol: 20, ISSN: 1745-6215
Kiss T, Wittenstein J, Becker C, et al., 2019, Protective ventilation with high versus low positive end-expiratory pressure during one-lung ventilation for thoracic surgery (PROTHOR): study protocol for a randomized controlled trial, TRIALS, Vol: 20, ISSN: 1745-6215
- Author Web Link
- Cite
- Citations: 27
Ampatzidou F, Boutou AK, Karagounis L, et al., 2019, Noninvasive Ventilation to Treat Respiratory Failure After Cardiac Surgery: Predictors of Application and Outcome., Respir Care
BACKGROUND: Respiratory complications remain a major cause of morbidity in cardiac surgery patients. This study aimed to determine the prognostic parameters associated with the application of noninvasive ventilation (NIV) for the treatment of acute respiratory failure, along with the possible predictors associated with NIV failure, among the subjects who underwent cardiac surgery. METHODS: This was a retrospective cohort study. Data on all adult patients who underwent cardiac surgery in a single center between May 2012 and December 2016 were analyzed. Multivariate regression analysis with bootstrapping was used to identify which baseline and intraoperative parameters were associated with the application of NIV to treat acute postoperative respiratory failure. A univariate analysis was also applied to identify potential variables associated with NIV failure. P < .05 was considered significant. RESULTS: A total of 1,657 subjects (mean ± SD age 65.2 ± 10.7 y; 21.7% females) constituted the study population, 145 (8.8%) of whom were treated with NIV due to acute postoperative respiratory failure. Body mass index adjusted odds ratio 1.02, bias-corrected 95% CI 1.01-1.04), EuroSCORE (European System for Cardiac Operative Risk Evaluation) II (adjusted odds ratio 1.11, bias-corrected 95% CI 1.02-1.32), COPD (adjusted odds ratio 4.004, bias-corrected 95% CI 2.53-8.93), and preoperative estimated glomerular filtration rate (adjusted odds ratio 0.99, bias-corrected 95% CI 0.98-0.99) independently predicted NIV application. NIV treatment failed in 16 of the 145 subjects (11%) and age, EuroSCORE II, COPD, heart failure, renal replacement therapy, and postoperative stroke were all univariately associated with the outcome. CONCLUSIONS: NIV successfully treated acute respiratory failure in the vast majority of cardiac surgery subjects and COPD, EuroSCORE II, body mass index, and preoperative renal function were independently associated with its application.
de Waal EEC, van Zaane B, van der Schoot MM, et al., 2018, Vasoplegia after implantation of a continuous flow left ventricular assist device: incidence, outcomes and predictors, BMC ANESTHESIOLOGY, Vol: 18, ISSN: 1471-2253
- Author Web Link
- Cite
- Citations: 26
Henderson B, Khodabakhsh A, Metsala M, et al., 2018, Laser spectroscopy for breath analysis: towards clinical implementation, APPLIED PHYSICS B-LASERS AND OPTICS, Vol: 124, ISSN: 0946-2171
Romano R, Cristescu SM, Risby TH, et al., 2018, Lipid peroxidation in cardiac surgery: towards consensus on biomonitoring, diagnostic tools and therapeutic implementation, JOURNAL OF BREATH RESEARCH, Vol: 12, ISSN: 1752-7155
Ananiadou O, Schmack B, Zych B, et al., 2018, Suicidal hanging donors for lung transplantation: Is this chapter still closed? Midterm experience from a single center in United Kingdom, MEDICINE, Vol: 97, ISSN: 0025-7974
Tatham KC, O'Dea KP, Romano R, et al., 2018, Intravascular donor monocytes play a central role in lung transplant ischaemia-reperfusion injury, Thorax, Vol: 73, Pages: 350-360, ISSN: 1468-3296
Rationale Primary graft dysfunction in lung transplant recipients derives from the initial, largely leukocyte-dependent, ischaemia-reperfusion injury. Intravascular lung-marginated monocytes have been shown to play key roles in experimental acute lung injury, but their contribution to lung ischaemia-reperfusion injury post transplantation is unknown.Objective To define the role of donor intravascular monocytes in lung transplant-related acute lung injury and primary graft dysfunction.Methods Isolated perfused C57BL/6 murine lungs were subjected to warm ischaemia (2 hours) and reperfusion (2 hours) under normoxic conditions. Monocyte retention, activation phenotype and the effects of their depletion by intravenous clodronate-liposome treatment on lung inflammation and injury were determined. In human donor lung transplant samples, the presence and activation phenotype of monocytic cells (low side scatter, 27E10+, CD14+, HLA-DR+, CCR2+) were evaluated by flow cytometry and compared with post-implantation lung function.Results In mouse lungs following ischaemia-reperfusion, substantial numbers of lung-marginated monocytes remained within the pulmonary microvasculature, with reduced L-selectin and increased CD86 expression indicating their activation. Monocyte depletion resulted in reductions in lung wet:dry ratios, bronchoalveolar lavage fluid protein, and perfusate levels of RAGE, MIP-2 and KC, while monocyte repletion resulted in a partial restoration of the injury. In human lungs, correlations were observed between pre-implantation donor monocyte numbers/their CD86 and TREM-1 expression and post-implantation lung dysfunction at 48 and 72 hours.Conclusions These results indicate that lung-marginated intravascular monocytes are retained as a 'passenger' leukocyte population during lung transplantation, and play a key role in the development of transplant-associated ischaemia-reperfusion injury.
Zeriouh M, Sabashnikov A, Patil NP, et al., 2018, Use of taurolidine in lung transplantation for cystic fibrosis and impact on bacterial colonization, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 53, Pages: 603-609, ISSN: 1010-7940
- Author Web Link
- Cite
- Citations: 11
Tomasi R, Betz D, Schlager S, et al., 2018, Intraoperative Anesthetic Management of Lung Transplantation: Center-Specific Practices and Geographic and Centers Size Differences, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, Vol: 32, Pages: 62-69, ISSN: 1053-0770
Boshier PR, Knaggs AL, Hanna GB, et al., 2017, Perioperative changes in exhaled nitric oxide during oesophagectomy, JOURNAL OF BREATH RESEARCH, Vol: 11, ISSN: 1752-7155
Boshier PRB, Knaggs A, Hanna G, et al., 2017, Perioperative changes in exhaled Nitric Oxide during oesophagectomy Dear Mr Boshier, ESDE meeting 2017
El Tahan MR, Pasin L, Marczin N, et al., 2017, Impact of Low Tidal Volumes During One-Lung Ventilation. A Meta-Analysis of Randomized Controlled Trials, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, Vol: 31, Pages: 1767-1773, ISSN: 1053-0770
ObjectivesThe link between ventilation strategies and perioperative outcomes remains one of the fundamental paradigms of thoracic anaesthesia. During one-lung ventilation (OLV), one lung is excluded from gas exchange and ventilation is directed at the dependent lung. The authors hypothesised that the use of low tidal volumes (VT) during OLV provides adequate gas exchange and improves postoperative outcome.DesignMeta-analysis of randomized clinical trials.SettingThoracic surgery.ParticipantsPatients undergoing OLV.InterventionsNone.Measurements and Main ResultsThe authors performed a meta-analysis of all randomized trials on low versus high VT during OLV in patients undergoing thoracic surgery. Outcomes of the study were gas exchange and airway pressures during and after OLV, postoperative pulmonary complications (PPCs), and hospital stay (HLOS). Fourteen randomized trials were selected, but only a few of them contained one outcome of interest. Low VT was associated with lower arterial oxygen tension, lower airway pressures, and higher arterial carbon dioxide tension at specific time points during OLV. Low VT was associated with preserved gas exchange after OLV, lower incidence of pulmonary infiltrations, and acute respiratory distress syndrome. Incidences of PPCs and HLOS were similar.ConclusionsThe use of low VT reduces airway pressure but worsens gas exchange during OLV. Preservation of postoperative oxygenation and reduction in infiltrates suggest a lung-protective modality with no demonstrable impact on PPCs and HLOS.
Paardekooper LM, van den Bogaart G, Kox M, et al., 2017, Ethylene, an early marker of systemic inflammation in humans, SCIENTIFIC REPORTS, Vol: 7, ISSN: 2045-2322
Ethylene is a major plant hormone mediating developmental processes and stress responses to stimuli such as infection. We show here that ethylene is also produced during systemic inflammation in humans and is released in exhaled breath. Traces of ethylene were detected by laser spectroscopy both in vitro in isolated blood leukocytes exposed to bacterial lipopolysaccharide (LPS) as well as in vivo following LPS administration in healthy volunteers. Exposure to LPS triggers formation of ethylene as a product of lipid peroxidation induced by the respiratory burst. In humans, ethylene was detected prior to the increase of blood levels of inflammatory cytokines and stress-related hormones. Our results highlight that ethylene release is an early and integral component of in vivo lipid peroxidation with important clinical implications as a breath biomarker of bacterial infection.
von Dossow V, Costa J, D'Ovidio F, et al., 2017, Worldwide trends in heart and lung transplantation: Guarding the most precious gift ever, BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY, Vol: 31, Pages: 141-152, ISSN: 1521-6896
- Author Web Link
- Cite
- Citations: 6
Andreasson ASI, Borthwick LA, Gillespie C, et al., 2017, The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion, Journal of Heart and Lung Transplantation, Vol: 36, Pages: 985-995, ISSN: 1053-2498
BACKGROUND: Extended criteria donor lungs deemed unsuitable for immediate transplantation can be reconditioned using ex vivo lung perfusion (EVLP). Objective identification of which donor lungs can be successfully reconditioned and will function well post-operatively has not been established. This study assessed the predictive value of markers of inflammation and tissue injury in donor lungs undergoing EVLP as part of the DEVELOP-UK study. METHODS: Longitudinal samples of perfusate, bronchoalveolar lavage, and tissue from 42 human donor lungs undergoing clinical EVLP assessments were analyzed for markers of inflammation and tissue injury. Levels were compared according to EVLP success and post-transplant outcomes. Neutrophil adhesion to human pulmonary microvascular endothelial cells (HPMECs) conditioned with perfusates from EVLP assessments was investigated on a microfluidic platform. RESULTS: The most effective markers to differentiate between in-hospital survival and non-survival post-transplant were perfusate interleukin (IL)-1β (area under the curve = 1.00, p = 0.002) and tumor necrosis factor-α (area under the curve = 0.95, p = 0.006) after 30 minutes of EVLP. IL-1β levels in perfusate correlated with upregulation of intracellular adhesion molecule-1 in donor lung vasculature (R(2) = 0.68, p < 0.001) and to a lesser degree upregulation of intracellular adhesion molecule-1 (R(2) = 0.30, p = 0.001) and E-selectin (R(2) = 0.29, p = 0.001) in conditioned HPMECs and neutrophil adhesion to conditioned HPMECs (R(2) = 0.33, p < 0.001). Neutralization of IL-1β in perfusate effectively inhibited neutrophil adhesion to conditioned HPMECs (91% reduction, p = 0.002). CONCLUSIONS: Donor lungs develop a detectable and discriminatory pro-inflammatory signature in perfusate during EVLP. Blocking the IL-1β pathway during EVLP may reduce endothelial activation and subsequent neutrophil adhesion on reperfusion; this requires further investigation i
Zych B, Garcia-Saez D, Ananiadou O, et al., 2017, 10 Years Experience with Maastricht Category III Donation After Circulatory Death (DCD) in Lung Transplantation (LTx) - Analysis of Early and Long-Term Results in Large Single-Centre Cohort, 37th Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT), Publisher: ELSEVIER SCIENCE INC, Pages: S144-S144, ISSN: 1053-2498
Thakuria L, Romano R, Goss V, et al., 2017, Surfactant Metabolism During Normothermic Ex Vivo Lung Perfusion, 37th Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT), Publisher: ELSEVIER SCIENCE INC, Pages: S91-S91, ISSN: 1053-2498
Thakuria L, Reed A, Simon AR, et al., 2017, Mechanical Ventilation After Lung Transplantation, CHEST, Vol: 151, Pages: 516-517, ISSN: 0012-3692
Fisher A, Andreasson A, Chrysos A, et al., 2016, An observational study of Donor Ex Vivo Lung Perfusion in UK lung transplantation: DEVELOP-UK., Health Technol Assess, Vol: 20, Pages: 1-276
BACKGROUND: Many patients awaiting lung transplantation die before a donor organ becomes available. Ex vivo lung perfusion (EVLP) allows initially unusable donor lungs to be assessed and reconditioned for clinical use. OBJECTIVE: The objective of the Donor Ex Vivo Lung Perfusion in UK lung transplantation study was to evaluate the clinical effectiveness and cost-effectiveness of EVLP in increasing UK lung transplant activity. DESIGN: A multicentre, unblinded, non-randomised, non-inferiority observational study to compare transplant outcomes between EVLP-assessed and standard donor lungs. SETTING: Multicentre study involving all five UK officially designated NHS adult lung transplant centres. PARTICIPANTS: Patients aged ≥ 18 years with advanced lung disease accepted onto the lung transplant waiting list. INTERVENTION: The study intervention was EVLP assessment of donor lungs before determining suitability for transplantation. MAIN OUTCOME MEASURES: The primary outcome measure was survival during the first 12 months following lung transplantation. Secondary outcome measures were patient-centred outcomes that are influenced by the effectiveness of lung transplantation and that contribute to the health-care costs. RESULTS: Lungs from 53 donors unsuitable for standard transplant were assessed with EVLP, of which 18 (34%) were subsequently transplanted. A total of 184 participants received standard donor lungs. Owing to the early closure of the study, a non-inferiority analysis was not conducted. The Kaplan-Meier estimate of survival at 12 months was 0.67 [95% confidence interval (CI) 0.40 to 0.83] for the EVLP arm and 0.80 (95% CI 0.74 to 0.85) for the standard arm. The hazard ratio for overall 12-month survival in the EVLP arm relative to the standard arm was 1.96 (95% CI 0.83 to 4.67). Patients in the EVLP arm required ventilation for a longer period and stayed longer in an intensive therapy unit (ITU) than patients in the standard arm, but duration of overal
Padukone A, Sayeed AK, Marczin N, et al., 2016, Salvage myocardial revascularisation in spontaneous left main coronary artery dissection with cardiogenic shock - the role of mechanical circulatory support, PERFUSION-UK, Vol: 32, Pages: 171-173, ISSN: 0267-6591
Romano R, Thakuria L, Sheibani S, et al., 2016, Inflammatory response following DCD and DBD lung transplantation, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Romano R, Thakuria L, Sheibani S, et al., 2016, Does perfusion with the organ care system influence inflammatory response in lung transplantation?, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.


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Published 10/11/2022; updated 14/11/2022
We pride ourselves on building and supporting all members of the workforce and so when we were approached by the British Junior Cardiologists Association (BJCA) about how we could best support those who work less than full time (LTFT) through the process of becoming a fully accredited member of our Society, we were delighted to accommodate their request and extend the benefits to other part-time (PT) members.
The BJCA put a proposal to the Advisory Council and it was agreed that all pre-accredited members who are working PT or LTFT should be granted additional time to collect logbook cases. Having consulted with the Accreditation Committee and office team we devised a new extension request process based on sliding scale of working times, to assist LTFT/PT workers with completing BSE accreditation courses within a timeframe which best enables them to achieve their professional aspirations. Those who successfully apply for a BSE LTFT/PT extension request will have their logbook submission deadline extended appropriately in accordance with the percentage of hours they work. Those working 60% and below will receive a 24 month extension whilst those working 61% and above will receive a 12 month extension.
To complete the process, those who have passed their BSE theory examination can apply for the extension via our BSE extension request page, making sure to complete the form to the best of their abilities and including signed supporting evidence from their Head of Department. Members will not be charged a fee for this extension.
Dr Will Jenner, LTFT Representative for the BJCA and Dr Stephanie Hambleton, BJCA Representative for the BSE said "The BJCA exists to facilitate and support cardiology trainees with all aspects of training. Training less than full time (LTFT) can help to balance individual commitments, and the BJCA supports LTFT trainees to have equivalent access to training as full-time colleagues. We are delighted to have worked with the BSE on LTFT echocardiography accreditations, and the BSE have now created a logbook submission extension that reflects the lengthened duration of LTFT training. This extension system will be applicable to all staff that are LTFT and working towards BSE accreditation, ensuring that everyone has the opportunity to pursue the high standards of echocardiography set by the BSE."


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Download the School calendar 2023-2024 (Official) |
Haiti - France : New scholarship students in France 06/09/2011 14:46:47 Camille Galap, member of the Franco-Haitian committee and and Director of the University of Le Havre, Eliane Talbot, Vice-Chair of the Board of Studies and Student Life, accompanied by four Haitian Studies already studying have welcomed the newcomers. "Our goal is to create a teaching staff to rebuild Haiti [...] Le Havre University and others in France, show solidarity with the Haitian students who can no longer study [in their country]. These universities, are part of the Association of Universitie and French institutions for the Reconstruction of Haiti" reported Camille Galap "Last year the city of Le Havre and the community of the city of Le Havre (CODAH) have participated in funding studies for the Haitians" a funding that would have failed without the additional financial support from the Ministry of Foreign Affairs. Thay are scholarship students of the French government. Alfonso Rodriguez International Management student, wishes with the Master "put into practice what I would have learned throughout the year to help in the advancement of my country." as Dhaiti Erassaint also in International Management. Arnelle Blain, a student in applied economics and project analysis explains "Haiti has some shortcomings and the French know will allow me to make my contribution to the reconstruction of my country". As for Gregori Calix, in Master of Computer Science, he hopes to ""take advantage of what I will learn to innovate in the field of IT. Computerize Institutions, the State and help them to work." S/ HaitiLibre
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May 23, 2016
With proposals for privatization of air traffic control (ATC) still being pushed as part of the FAA reauthorization debate in Washington, DC, it is imperative that regional business aviation groups continue reaching out to their congressional representatives, NBAA President and CEO Ed Bolen said at the fourth annual NBAA Local and Regional Group Leadership Roundtable, held May 18 in Boston, MA.
"We need you to keep on doing what you've been doing: tell your elected officials why communities, companies and citizens across the country would be adversely impacted by ATC privatization, which would hand control of the system over to an airline-centric board of directors," Bolen told attendees. "This would put general aviation at risk and would threaten the economies of rural communities, which rely on general aviation."
The importance of regional business aviation groups was front and center at the roundtable, which was attended by more than 50 aviation advocates, representing 32 business aviation groups from across the country.
Bolen acknowledged the dozens of local groups that have answered NBAA's Call to Action regarding H.R.4441, the bill which would privatize the nation's ATC system, create a board of directors dominated by airline interests to oversee it, and implement new user fees to help pay for it. Bolen thanked the leaders with these groups, who also answered NBAA's call to let Congress know they supported the Senate version of the bill, which reauthorizations the FAA without privatization measures.
The roundtable was yet another affirmation of how valuable and successful regional business aviation groups are in mobilizing on behalf of the industry's priorities at the local and regional levels.
"In less than four years, the number of active regional aviation groups, as well as attendance at the roundtable, has nearly doubled," said Steve Hadley, NBAA regional program director and Southwestern regional representative. "The roundtable is structured so that attendees from new groups can network with veteran business group leaders, attend workshops, and in one day learn pretty much everything about the best practices involved in getting their own group started."
According to Hadley, about 30 percent of this year's attendees were there for the first time, many of them from the New England area.
In addition to Bolen, key speakers at the roundtable this year included Amy Lind Corbett, FAA Northeast regional administrator; Jeffrey DeCarlo, Massachusetts state DOT aeronautics director and Massachusetts state legislators Sen. Donald Humason and Rep. Danielle Gregoire.


text: 3 months Net Profit UP 128.7%, Revenue UP 43.1% vs last year www.jamstockex.com/?tag=CHL&category_name=quarterly-financial-statements Cargo Handlers Ltd Q1 jumped by 143% | Business Live w Mark Croskery https://youtu.be/mSpmIX7avPQ $CHL.ja has released its Q1 report. Here's a #SOTRSummary-Revenue ⬆43%-Profits ⬆129% 🔥This seems to be largely driven by FX gains as well as share of profits (recall that the company purchased 30% of Buying House in December 2020). pic.twitter.com/5ydadq2pEJ— Stocks on the Rocks #SOTR (@stocksondrocks) February 11, 2022 Post navigation TJH Financial Results & Analysis for Q4 Dec 2021 Several changes for ICTOP10 listings


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For some of ya'll that might travel to NYC and would actually seek out bbq,here is one of the about five places that have opened in the last couple of years.
The menu setup is by Paul Kirk a comp cook,bbq teacher,cookbook author from KCMO.
R.U.B. is for Righteous Urban BBQ.
Have heard that one of the specials is a pork butt,a small pitcher and a couple glasses,and a loaf of bread for about $100.
Cheap by NYC standards.
Original Post


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Beginning college is a momentous milestone in one's life, but it can also be challenging or frightening at times, particularly if one has made the decision to study abroad. Here are some suggestions on how to make the most of your first year of college for the guys and girls who have just begun their college careers. Once you begin taking classes, keep these suggestions in mind, but more importantly, don't forget to enjoy yourself!
Tips for guys and girls starting their college journey:
Plan ahead and prioritise meeting deadlines
To keep track of all your due dates, exams, group sessions, and festivities, get a calendar, whether it be an online app or a good old paper diary. During your college years, you will have a wide variety of assignments, so the sooner you establish a routine that works for you, the better. Never submit an assignment late by making it your top priority. Being responsible and diligent is always advantageous.
Always keep in mind that everyone you meet in college will have something to offer you
At college, you'll come into contact with a huge number of new people, including your peers, instructors, advisors, recruiters, campus staff, etc. Naturally, not everyone will become your friend, but we advise connecting with as many folks as you can, especially if you're new to the university.
You may also like: Simple Techniques to Control Hair Fall in Teenage: Girls & Boys
Never, ever, ever plagiarise
Don't even think about plagiarising. Writing is a fundamental skill that you will develop while attending college. Don't sabotage the learning process by merely copying and pasting text from another source. Instead, gather enough diverse sources, master proper citation techniques, and establish your own writing schedule. You can also use one of the numerous tools and apps available to you that can identify plagiarism.
Identify a note-taking method that works for you
Although taking notes on a computer might be quicker and simpler than writing them down by hand, writing them down with a good old-fashioned pen could perhaps help you recall the lecture's material better. Find out what suits you best in each class so you can get the most out of your notes when you're studying or revising.
Maintain a healthy lifestyle
Every day of your life, trying to take good care of both your body and mind is important. However, when you begin a brand-new chapter at a college, often hundreds of miles from your family and home, it is even more important. You'll probably experience frequent temptations to eat unhealthily, prepare inexpensive meals, and forego physical activity due to a lack of time. However, it's critical to maintain a healthy lifestyle, including regular exercise, good sleep habits, eating enough fruits and vegetables, drinking enough water, and all of the above. The bottom line is that your health is the cornerstone of everything else, so take care of it.
Engage in activities that your faculty or university sponsors
These events, whether they are faculty-organised Christmas parties or extracurricular lectures, are a wonderful way to learn new things while also getting to know your classmates, professors, and professionals better.
Join clubs and organisations for students
Participating in a student club or organisation gives you the opportunity to improve your cover letter and have a voice in how things are run in addition to increasing your networking opportunities and, most likely, your social circle.
Try out new things
Academic achievement isn't the only metric of college success. You might want to take advantage of your time in school to pick up brand-new skills or learn subjects that aren't fully covered in your other college courses. An alternative metric for progress might be experiential if you place a high value on exploration and adventure. Do you find your coursework to be fulfilling? Do you put yourself through interesting challenges?
Occasionally enrol in classes that sound enjoyable if you want to take advantage of the variety of courses your school offers. Increase your scope by taking extra classes. Choose a minor in a subject that interests you. Your brain may benefit greatly from it, enabling you to face fears, inspire creativity, and discover new facets of yourself.
What other tips would you offer all the guys and girls starting their college journey? Let us know!
We will be delighted to have your thoughts and feedback. Please write to us at [email protected]
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Purchase this article with an account.
C.–Y. Hu, C.–H. Yang, C.–T. Tu, W.–Y. Chen, C.–J. Huang, H.–J. Tsai; Knockdown of Zebrafish Pitx3 Gene Affects the Early Development of Lens . Invest. Ophthalmol. Vis. Sci. 2005;46(13):1882.
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© ARVO (1962-2015); The Authors (2016-present)
Abstract: : Purpose: The homeobox gene, PITX3, is associated with the anterior segment mesenchymal dysgenesis and congenital cataract in humans. In this study, we attempt to investigate its effect on lens development by way of gene knockdown in zebrafish. Methods: We microinjected Pitx3 morpholino oligo–nucleotides (MO), a translational inhibitor specific for Pitx3, into 1– to 4–celled zebrafish embryos. In order to observe their lenses in vivo, some morphants and normal controls were treated with 0.003% 1–phenyl–2–thiourea (PTU) every day to inhibit melanogenesis. At 72 hours post–fertilization (hpf), their left eyes were photographed for measuring ocular dimensions. The results were analyzed with 2–tailed independent t–test. Some larvae untreated with PTU were fixed for histological examination. We also performed Western blot and immunohistochemical stain to show the amount and location of alpha–A–crystallin, the major lenticular structural protein, in 72–hpf controls and Pitx3 morphants. Results: After microinjection of 3, 6, 7.5, or 9 ng of Pitx3–MO per embryo, more than 94% of morphants survived at 24 hpf and less than 8% of survived morphants had deformed body axis at 72 hpf. Grossly morphants had less bulging lenses, or even were aphakic. Image analysis proved that morphants' eyes and lenses were significantly smaller than those of the controls, but their anterior chamber depth and retinal thickness did not differ. Western blot analysis showed that the 20–kD alpha–A–crystallin was less in morphants. Histological examination revealed that morphants had smaller lenses, but their retinal structure was similar to that of controls. Immunohistochemical stain showed decreased alpha–A–crystallin in the lens of Pitx3 morphant. Conclusions: Knockdown of Pitx3 gene did not significantly affect the early gross development, except for arrested lens development and microphthalmia which was associated with inadequate lenticular alpha–A–crystallin synthesis.
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Still no sighting of the Soup Dragon?
NASA releases asteroid flyby video from Dawn probe
NASA has released a new video showing Vesta, giant queen of the asteroid belt, in unprecedented detail. One of the highlights of the new data, collected by NASA's ion-engine space probe dawn in orbit around the mighty space boulder, is an espceially precipitous region located at the body's south pole. The space agency …
Tuesday 20th September 2011 04:48 GMT Steven Roper
@ Ragarath
No, because the kind of compulsive whingers you're talking about will form the Society for the Preservation of Asteroids or something, insisting that these untouched marvels of nature should remain untouched.
Remember, these people are born to complain. They have to have something to whinge about.
Tuesday 20th September 2011 11:42 GMT Purlieu
Again, like last time, you omit the fact that there is no sea on the asteroid. Taken from the lowest point on Earth (Challenger Deep for example) to the top of Everest easily beats this puny 15km pimple. Please keep comparisons equal.
Meanwhile, just in case, I for one welcome out pimply asteroid based space mountain masters


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What is the safest chat room?
- Go! Chat for Facebook.
- Google Hangouts. Google changed its chat app from Gtalk to Google Hangouts.
- ChatSecure. ChatSecure is an amazing app, which retains your conversations safe and private.
- Signal Private Messenger.
- Silent Phone – Private Phone.
- ChatzyFree.
- 7. Yahoo! Messenger – Free Chat.
At just one click you could begin chatting without registration however you shall make sure not to be imply. If you need to make new good friend online, otherwise you just need to kill some time, then web chat rooms might be for you. The list under lists the Top 10 Chat Room web sites and does not include the popular Chat Apps, like SnapChat, Whatsapp, Line and others. For a listing of one of the best chat or messaging apps, please go to our page Free Chat Apps.
Courting Com
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What is the distinction between a chat and a textual content message?
If you see "Chat" in the typing field when sending a message, you know you're utilizing Chat options. If you see "Text" within the typing field when sending a message, you know you're utilizing Text (SMS/MMS).
Yes, you'll be able to indeed have enjoyable in free adult chat rooms which are obtainable to use freed from value. There are various choices available that allow you to chat with strangers and random folks with out registering. You can chat in private, public, and group grownup chat rooms which would possibly be particularly designed only for you. Elitemate is considered one of only some web sites that enables its customers to make the most of their cellular app in a non-conflicted method. For individuals which have been on the lookout for an built-in and complete expertise, the courting site's website and the app are the way to go.
Is It Authorized To Use Grownup Chat Rooms?
Chat Rooms are proving to be a great mode of reduction for many individuals. Either you're a teen, an grownup, ladies, males or from any age group, chat rooms had been and can at all times be the best place to move your time and overlook your sorrows. Getting to know new folks and sharing your emotions could be very easy in an online chat room.
Which is no 1 chatting app?
Topping the list of most popular messaging apps globally, you'll be hard-pressed to seek out anybody who hasn't used WhatsApp earlier than. With group chat options and end-to-end encryption, it's not exhausting to see why WhatsApp is such a frontrunner within the social messaging sphere.
Click on the room you want and get chatting just about right away. Once you land on the location you'll be able to entry the teenage chat room proper from the homepage which makes it simple to use. The chat room is moderated by different volunteer teenagers who ensure everyone seems to be chatting safely. The site is heavily moderated making it one of many safest chat site for youngsters. It is probably certainly one of the finest chat web sites and you can also view who is watching you along with consumer profiles with pictures. This website is extra about assembly up new individuals than simply pure chat.
Finest Free Online Chat Room Sites
Customization choices keep the server participating, protected, and on matter. Users interested in free chat rooms will discover restricted choices talkwithstranger on Paltalk. Free rooms exist on the network, however it's challenging to search through them, and most aren't very energetic.
What is Kik principally used for?
The main functions of Kik are:
Send messages, movies, pictures, gifs, etc. Group chat (with as a lot as 49 different users) Anonymous chat. Promoted Chats allow users to comply with and chat with totally different manufacturers in music, entertainment and more.
Chat rooms for adults are an effective way to make new friends or join with strangers in a secure and safe surroundings. You can communicate privately with different adult customers who share your pursuits. They are completely free and you can either join anonymously or register your name. Tinychat permits customers to chat online by way of voice chat, immediate messaging and video chat. Chat rooms for dating let you meet and chat seamlessly with your chosen individual.
Share Images And Movies In Chat
● The platform presents themed rooms and a highly customized stickers shop. ● The website engages a substantial consumer base and, consequently, fosters a highly active group. If you have a particular chat room that you simply want to register, you'll be able to merely enter the name of that particular chat room and seek for it utilizing it as your search keyword. Each group can hold up to 200,000 members, making it easy to chat with others who share your curiosity.
- This person could presumably be your common man or gal, however they could even be a professional grownup star.
- You can play many wonderful games on the platform like Uno, Trivia, and many more.
- You also get the choice to create a friend listing to keep observe of the individuals that you just really feel a reference to and would like to connect with later.
- Enterchatroom allowed you to have free online chat with strangers.
The website has undergone some cosmetic modifications over the years to maintain it modernized and entertaining, and we predict it's carried out a very good job. For fast adult chat, there really isn't a greater choice than Chatroulette. Jerkmate is a free sex chat site that claims you'll by no means should masturbate alone once more. It additionally calls itself the ultimate live masturbation experience. If you couldn't tell by the name, Jerkmate will allow you to discover a jerk-off associate by way of their group chat sessions or one-on-one chats.
EliteSingles.com is an easy-to-use website that incorporates an intuitive interface. However, the registration course of is a bit longer since it includes an inventory of questions that users are obligated to answer to build an optimized profile. Moreover, the platform is exclusively out there for US citizens. There are lots of free chat rooms accessible on the platform, including Australia, Indonesia, singles, Africa, and plenty of more.
Chat free of charge is provides free online chat room with webcam characteristic. There are varied chat rooms available in it like singles, USA, Australia, women, Canada, Indonesia, Spanish, Africa, Portugal, Germany and many extra like it. You can also add pals to your contact chat, and extra you can share footage with your family and associates. While it is true that a free sex chat site for adults presents some great benefits, there are also some cons that you must think about before becoming a member of. One of the main cons is that you won't be capable of discover your friends amongst a big pool of people.


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2023-11-24 17:54:30
The Timeless Appeal of Square Tiles in Kitchen Design
I. Introduction
Square tiles have stood the test of time, remaining a staple in home decor for their symmetry and simplicity. In the heart of the home—the kitchen—square wall tiles offer a blend of functionality and style that can complement any design theme. This article will explore the charm and versatility of square tiles, particularly in the kitchen, and how they can transform your cooking space.
II. The Classic Elegance of Square Wall Tiles
Square tiles are incredibly versatile, making them suitable for both modern and traditional kitchens. Their uniform shape allows for a variety of patterns, from a straightforward stacked layout to a more intricate herringbone pattern. The clean lines of square tiles can create a sense of order and spaciousness, making them an excellent choice for kitchen walls.
III. Cream Square Kitchen Tiles: A Warm and Inviting Choice
Cream square kitchen tiles exude warmth, creating an inviting atmosphere where family and friends can gather. These tiles pair beautifully with natural wood finishes, metallic accents, and a range of countertop materials. When designing with cream tiles, consider using contrasting grout colors to add depth or matching grout to create a seamless look.
IV. Brightening Your Space with White Square Kitchen Tiles
White square kitchen tiles are perfect for brightening up your kitchen, reflecting light to make the space feel larger and more open. They serve as a blank canvas, allowing other elements of your kitchen to stand out. To maintain their pristine appearance, regular cleaning with gentle, non-abrasive products is recommended.
V. Selecting the Perfect Square Kitchen Tile for Your Home
When selecting square kitchen tiles, consider the color, size, and finish that best fit your space. A glossy finish can reflect light and add vibrancy, while a matte finish offers a more subdued, contemporary look. Grout color and tile spacing are also crucial, as they can dramatically alter the appearance of your tiled wall.
VI. The Modern Sophistication of 10x10 Porcelain Tile
10x10 porcelain tiles are a popular choice for their durability and modern appeal. These tiles are resistant to stains and moisture, making them ideal for the kitchen environment. Experiment with different layouts, such as a diagonal or basketweave pattern, to give your kitchen a unique and personalized touch.
VII. Installation Tips for Square Kitchen Tiles
A successful tile installation starts with proper preparation, including a clean, level surface and the right adhesive. While some homeowners may opt for DIY installation, professional help can ensure precision and longevity. Consider the complexity of your chosen pattern and your own skill level before deciding on the best approach.
VIII. Conclusion
Square kitchen tiles offer a timeless beauty that can elevate any kitchen design. Whether you choose the subtle elegance of cream tiles, the crisp brightness of white tiles, or the contemporary feel of 10x10 porcelain tiles, these square wonders are sure to enhance the heart of your home. Explore the various options available and embrace the enduring appeal of square tiles for a kitchen update that will last for years to come.


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Dilshat Djumanov, Director of Data Science at Richmond Pharmacology explores how GDPR is central to protecting private information. From clinical research to patient monitoring, the collection and sharing of data is key, as outlined by Dilshat Djumanov, Director of Data Science at Richmond Pharmacology. In their PM Live article published today, Djumonov explores how GDPR is central to protecting private information while presenting unique challenges to the pharmaceutical clinical trials industry. The post Brexit control of critical data and the ability to share information adds to the complexity with the UK planning its own reforms under the Data Reform Bill.
These regulatory changes, and other in the various frameworks around the world, are helping the integration of data management tools and realise the potential benefit for both industry and patients of better data-sharing tools. Unlocking the next generation of data sharing, processing and visualisation in clinical trials will be the next great frontier in pharmaceuticals. Medical privacy has been at the core of trial participation for a long time and the clinical research industry is perhaps the most advanced in understanding how to safely handle sensitive personal data.


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We follow the highest manufacturing standards with passion! Anima Mundi is a family owned and operated business. Our superfoods are made in an FDA registered and cGMP certified facility, made in the U.S. with certified organic herbs and wild harvested plants in a vegan and gluten free kitchen. Our products contain zero fillers, binders or flow agents. They are lab tested for purity and efficiency.
Ginger Powder, Organic 4 oz BULK BAG
$ 14.50
Botanical Name: Zingiber officinale
Organically grown in China and India, depending on the season
Ginger is a warming and spicy herb that has been used all over the world as a culinary herb and digestive aid, particularly in healing nausea and stomach upset. It has been traditionally used for its anti-inflammatory and adaptogenic properties as well.
Suggested Use: Add 1 tsp to your favorite tea, juice, or healthy meal, 1-3 times per day.


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FAQ 1500 Do HIPAA protections apply to the health information of individuals, INDEX
This is information regarding HIPAA's applicability to deceased persons.
Issued by: Office for Civil Rights (OCR)
Do the HIPAA Privacy Rule protections apply to the health information of deceased individuals?
Yes, for a period of 50 years following the date of death of the individual. During this period, the Privacy Rule protects the identifiable health information of the deceased individual to the same extent the Rule protects the health information of a living individual. However, in cases where a covered entity maintains a medical records archive or otherwise maintains health or medical records that contain identifiable health information on individuals who have been deceased for more than 50 years, such information is not considered protected health information and may be used or disclosed without regard to the Privacy Rule.
HHS is committed to making its websites and documents accessible to the widest possible audience, including individuals with disabilities. We are in the process of retroactively making some documents accessible. If you need assistance accessing an accessible version of this document, please reach out to the firstname.lastname@example.com.
DISCLAIMER: The contents of this database lack the force and effect of law, except as authorized by law (including Medicare Advantage Rate Announcements and Advance Notices) or as specifically incorporated into a contract. The Department may not cite, use, or rely on any guidance that is not posted on the guidance repository, except to establish historical facts.


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They are currently in talks with McG to direct the project, while Hyde Park Entertainment and WWE Studios is financing the film.
- Hulk Hogan's agent Peter Young stance that he didn't signed off on appearing in WWE 2K14. As previously reported, Eric Bischoff had argued that Hogan didn't sign off on it and that WWE had been utilizing existing rights.
Young claims he made a deal in 2008 with THQ for Hogan to appear in a WWE video game and that 2K Sports picked up the renewal option on Hogan's contract when they bought the WWE video game license after THQ's bankruptcy.
WWE 2K14 creative director Cory Ledesma had previously said that the game had to get over the "hurdle" of setting Hogan involved in order to make the "30 Years of WrestleMania" mode possible.


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You may gamble on your favorite games and play over 2,000 different slot machines, making this a really one-of-a-kind gaming platform.
This is a truly global platform, as evidenced by their Curacao license. In this 20Bet Review, we'll take a look at the site's various features, including their Welcome Bonus, Games, and Support. Get moving!
Promotions and Bonuses at 20Bet
First Deposit Bonus: 100% up to €120 + 120 Spins (certain countries excluded)
When 20Bet first opened its virtual doors, new customers were treated to a fantastic welcome bonus consisting of a 100% match on their initial deposit and a number of free spins. It appears that they have decided to stop offering incentives to residents of certain nations, particularly those in the Nordic region.
It's unknown why they've chosen this path; nonetheless, there are likely other contributing factors. The incentive may not be accessible now, but that doesn't mean it won't be again. As soon as we have more data, we will update this review.
Can I trust 20Bet to pay out winnings?
It certainly is. TechSolutions Group, headquartered in Cyprus, also has an office in Curacao, where this site is hosted. 20Bet is regulated by the Curacao Gaming Control Board thanks to Antillephone NV's gaming and betting license.
Do bets on 20Bet cost anything?
20Bet does not charge any fees for making deposits or withdrawing funds. Providers of these services may assess fees for dealing in a currency other than their own. You don't have to worry about this as long as your currency of choice is the Euro.
In 2023, what is the 20Bet signup bonus like?
The welcome bonus consists of 120 free spins and a 100% match up to €120 for new customers. Regrettably, not everyone of Northern Europe can take advantage of this kind invitation.
The 20Bet Wallet
20Bet accepts a wide variety of payment options, making it easy for any customer to fund their account. There are now the following choices available to you:
Money Orders
You may fund your account by visiting the Cashier and entering the desired deposit amount. Both deposits and withdrawals must be a minimum of 10€.
We were a little dissatisfied to see that rapid bank payment methods like Sweden's Trustly and Zimpler, or Germany's Sofort, weren't supported by the casino. You won't have to wait long to stop wondering whether and when your next withdrawal will arrive.
When you play at 20Bet, your withdrawal will be processed in no more than 24 hours. Your chosen method's transaction time must also be added. E-wallets are preferable to credit or debit cards since the funds are typically available within a few hours, rather than waiting the standard three to five business days.
When making your initial withdrawal request, you may be asked to provide identification details such a passport photo and evidence of residence. You'll only have to go through this process once, but it might take up to three days for 20Bet's security staff to review and approve your papers.
Picking 20Bet Games
The games on 20Bet.com are organized into the following four categories:
Casino has a wide variety of table games and slot machines, some with life-changing jackpots.
Roulette, Blackjack, Baccarat, Poker, and Game Shows are all available at the live casino.
More than fifteen hundred sporting events from across the world are available for wagering.
Bet in real time on major football leagues and other sports.
Over 4,200 distinct titles are available for your perusal in this section alone! Game developers like NetEnt, Push Gaming, Thunderkick, Play'n GO, Big Time Gaming, and many more provide these. You can see that there are many well-known names, guaranteeing that you will get access to the most recent and popular releases.
20Bet has organized its huge library of games into a few distinct categories for your convenience. There, you'll find a wide variety of filters, such as "Popular Games," "New Games," "Jackpots," "Bonus Buy," and so on.
Online Casino
20Bet also has a top-notch live casino. It has almost 200 games from over a dozen developers. While some of the tables remain faithful to their historic forms, others include innovations and maximum payouts that would be unthinkable in a land-based casino.
Power up Roulette, Baruto Baccarat, Sweet Bonanza Candyland, Music Wheel, One Blackjack, and Mega Sic Bo are some of our favorite new games. Trying out these games was a lot of fun.
20Bet Sportsbook
Next, we have Sports Betting, followed by Live Betting, and finally Casino. At the time of writing this 20Bet review, the site offered odds on more than 1,700 different events, and new options are being added every hour.
All the major sports leagues are covered, and the biggest games are included along with favorable odds. 20Bet also provides Live Betting on the vast majority of their ongoing matches, so there's no need to stress if you miss the deadline to place your wagers.
Portable Media Players
You can't provide a full gaming platform in 2018 without a reliable mobile option. 20Bet is a casino website that is compatible with most devices; the only difference will be in the games available. Visit the site from your mobile device and sign up for an account or log in to begin playing immediately.
The 20Bet iOS and Android app is available for your convenience. The website will provide a link and detailed instructions. Sports betting, slot machines, and live dealer casino games are all accessible through the app. You may use their app to view the latest scores from all of your games as well.
Title and Ownership
The site is run by TechSolutions Group, a Cyprus-based firm that is licensed as a casino by AntillePhone NV, the master license holder in Curacao. When it comes to online gambling, they make sure that 20Bet abides by all of Curacao's rules and regulations.
Therefore, you may play at 20Bet with total peace of mind. If you have a problem with a casino that you can't resolve by talking to an employee there, you may always contact AntillePhone (email@example.com).
Brands like National Casino and Bizzo Casino are part of TechSolutions' extensive collection. If you liked playing at these sites, you will probably also love 20Bet, the company's crown jewel.
Help With 20Bet Casino
The availability of customer service at all hours is crucial for foreign casino sites like 20Bet. While it's still late evening and ideal time for games in other parts of the world, it's early dawn in Scandinavia. 20Bet's live chat makes it easy to get in touch with their multilingual support staff.
Simply provide your name, email address, and language preference. You'll be connected with a helpful representative shortly. It's possible that you'll have to wait a while if the staff is currently swamped. In that case, please review the Frequently Asked Questions and the Terms and Conditions on 20Bet's website.
20Bet is a gambling website like many others, and like many others, it offers Sports betting in addition to Casino and Live Casino. 20Bet, however, has perfected the implementation, unlike its rivals.
Providing a wide variety of games does not cause any of the other areas to suffer here. Instead, it offers fantastic collections of games of all genres. One of the few things we might maybe find fault with is the lack of a welcome bonus at the moment, but other than that, there isn't much to criticize.
The customer service crew at 20Bet is fantastic, and they will go out of their way to address any issues you may have. You can be certain that the team behind 20Bet understands exactly what they're doing when it comes to running a casino, so you can enjoy yourself here without any concerns.


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Australians generally are appalled by animal cruelty and are often unaware that their supermarket purchases support the cruel pork industry.
The pig industry has been clever at keeping it's secrets, knowing that many Australians would refuse to buy pork products if they were informed of the cruelty in factory farms and during the slaughter process.
Pigs are as intelligent as dogs, they are social animals and form strong relationships in small family groups.
Despite this consecutive governments have provided legal exceptions for farmers, to prevent them being prosecuted for animal cruelty, so they can maximise their profits.


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Here is one of two of Colleen's hand signed prints. We have given it a "postage stamp" border and used a continuous heart cutting style for a nice interlocking puzzle. While the puzzle has disguised corners and probably a few other tricks, it is not as difficult as some of our puzzles and should provide a nice afternoon of fun.
Title: Spring Praises by Colleen Sgroi Edge Style: Tight wave (Postage Stamp) Size: 10" x 8" with about 160 average-size pieces
As with almost all our puzzles, we have included some figural pieces. There is a heart in the hearts, a kite flying in the breeze, a teddy bear and a pony looking at the rocking horse in the picture.
You can see Colleen's had signature below.
The example puzzle is made from 5 ply void-free (no interior defects) cherry plywood with poplar core. As with all our puzzles, the back is finished the old-fashioned way with multiple coats of hand-rubbed oil and shellac. The back of the puzzle is as nice to look at as the front.


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Blueprint optimized data organization for a top safety and wellness solutions provider, consolidating 19 AWS environments and multiple Databricks setups, enhancing efficiency.
Empowering subsidiaries with critical customer insights
Blueprint utilized Databricks, Microsoft Azure, and Adobe Preference Center to clean 99% of data from the newly acquired subsidiaries of a major HVAC service group, significantly speeding the ability to launch integrated, intelligent marketing campaigns.
Client Snapshot
Who: National HVAC Equity Business
Industry: Utilities
Stakeholders: CIO, CMO, Corporate Marketing Team
Domain: Know Your Customer / Customer 360
Relevant Technologies & Software: Databricks, Microsoft Azure, Melissa data, Adobe Preference Center
Work Summary
What we did: Make disparate data from various subsidiaries unified, accessible, and reportable. We worked iteratively, providing data incrementally so that the client could start working with their data quickly.
Results: Helped to make the client's Databricks instance viable for business insights when compared to cost. Provided centralized data for marketing reporting.
The challenge
Our client, a home repair and services equity firm, was struggling to effectively leverage its data management system after acquiring 15 regional home repair and improvement service companies. Each subsidiary had its own data inputs, processes, and formats, which the client wanted to centralize to analyze for marketing and business insights. Additionally, their in-house team had a limited understanding of Databricks, Spark, and cloud infrastructure providers like Microsoft Azure, in which the company had recently invested.
Identifying valuable data in the HVAC contractor space
Operating within the HVAC service industry, our client's subsidiaries each received service-specific requests. Once a request was received, the subsidiary would agree on a quote with the customer and send a repair person or installation team to fulfill the request. Alongside each request, the subsidiary collected valuable information that included customer identity and geographic data, service type and cost, seasonal fluctuations in business needs, promotional offer redemption, service duration, and the rate of required follow-up service. Each of these data points contributed to building a comprehensive picture of the customer journey, including region-specific data that could be utilized to enhance sales, plan for seasonal needs, and more.
Given the breadth and depth of data being collected, it's common for in-house IT teams to encounter difficulties when it comes to establishing a software environment to process, centralize, deduplicate, and extract the meaningful insights needed for a 360-degree view of business operations. A limited understanding of their cloud investments, like Databricks, often results in roadblocks at the project and operational level that prevent the successful development of a functional and useful system.
Building the foundation for repeatable data access and insights
From millions of rows of customer data, Blueprint engineers created an end-to-end data pipeline on the Azure Databricks platform, enabling the client to view the best-ranked, most-current, and highest-confidence records to execute marketing campaigns. Built on principles that make replication simple, the user-friendly architecture and model can generate reports across the business without having to reengage Blueprint or hire additional consultants.
Any company with franchise or subsidiary needs that include centralizing data and processes for operational or marketing reasons would benefit from this type of use case. Once data is centralized, Blueprint can assess current business operations, drilling down into the granular data that is critical for understanding consumer demand, operational inefficiencies, projected revenue, and more.
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Starting with the development of a modernized data estate, Blueprint worked to adjust this waste management company's IT capabilities, creating a secure data environment for planned acquisitions and future business needs.


text: Pale green glazed faience scarab shaped seal with details of the head and legs on the back, and flat base inscribed with a winged cobra flanked by two nefer signs and a 'nb' or water sign at the bottom. Pierced through the length for suspension. Remains of green glaze only on the base. Dated by Professor Sayce to 1500 BC. Described by donor, Mr Frank Stevens, as coming from Cyprus.