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Predicated on judges, proof is actually insufficient to demonstrate that Karadzic and his awesome co-perpetrators meant to individually wreck Bosnian Muslims and you will Croats throughout these municipalities
Are regarding Prijedor, I'd to come quickly to words with the devastating impact of Karadzic's eyes on my family members, my community, my personal birthplace, my life. While the a journalist and later since the an employee of one's ICTY, all that I've done during the last 2 decades has somehow been shrouded inside the Karadzic's black shade. I am aware too many people that happen to be nevertheless looking for its kid's skeleton to help you bury. I understand too many people whom killed, inebriated toward Karadzic's eyes away from Bosnian Serbs' right to mind-determination where childhood friends was in fact became "historic foes."
Have a tendency to You will find dreamed during the day he had been planning pay it off every, whenever justice will be served up on your, cooler and you may merciless. Immediately after which, more 20 years immediately following he was first indicted, the day appeared. Or in other words, it crashed abreast of people, featuring its mass media madness, with a huge selection of opportunists eager become an element of the spectacle any way offered, which have an effective cacophony regarding voices calling for his lead, calling for your as beatified, voices yelling "genocide", voices warning off dreadful, dreadful outcomes should the view be employed to alter the position quo their criminal activities written, voices requiring, pleading, intimidating…
Amidst so it noisy audio, Karadzic registered court docket with a good beaming laugh, probably relying on the fresh day's result, satisfied that the jewish chat room good fresh fruit out-of their soft work in the Bosnia and Herzegovina – their this new regular off office, hatred, mistrust and you may breakup – are real time and you will booming.
The fresh wisdom consisted of zero shocks, unless one to counts the fresh acquittal with the charge out-of genocide for the municipalities such Prijedor because the a surprise. I don't. Inside Srebrenica sure, said evaluator, and then he are duly convicted regarding genocide into 1995 annihilation of some 8,000 men and you may guys. However, someplace else he merely designed to exterminate, not myself ruin, judges influenced. Unpalatable entry to court nuance, sure, yet not shocking.
New extreme characteristics out of procedures envisaged for utilization of this plan are most readily useful caught from the result of new freshly appointed leader of your Bosnian Serb Military, Standard Ratko Mladic
The guy climbed into podium in the fulfilling of your Serb construction on twelve, 1992, where the document was initially showed, and you may treated the brand new people in politics prior to him: "You can't sort somebody as a consequence of a web so as that one to people falls because of while the other remains. What you are inquiring us to manage are natural and easy genocide." It don't mean Mladic perform reject the newest demand; since decision was developed the guy observed it having fervor and fanaticism.
Most of Karadzic's view got already been written in prior verdicts against their co-perpetrators, members of the new Bosnian Serb governmental and you may army frontrunners: Momcilo Krajisnik, Biljana Plavsic, Radoslav Brdjanin, Stojan Zupljanin while others. Although never assume all the fresh new issues emerged, the fresh new wisdom laid out in detail the picture of Karadzic's trick role when making an enthusiastic ideology that de–humanized the new low-Serbs to the stage where the extermination turned a valid, necessary national efforts.
The judges had been particular in outlining that it proof: "Radovan Karadzic was at the brand new forefront of fabricating and you will promoting the fresh new ideology and rules of SDS and you will carrying out the new synchronous political, military, police and you can governmental formations which were regularly present and sustain expert more than Bosnian Serb-reported region and further the intention of [removing non-Serbs due to fee out-of criminal activities]. He was central within the detailing the goals of your Bosnian Serb leadership along with breakup out of Bosnian Muslims and Bosnian Croats, the brand new take-more regarding Bosnian Serb-stated region, and the creation of a generally ethnically homogeneous Bosnian Serb county. Karadzic was also a main contour on the dissemination off propaganda against Bosnian Muslims and you will Bosnian Croats, and that known her or him due to the fact historic opposition of your own Serbs and you may insisted you to co-lifetime is actually hopeless. The guy played with this historical story along with his rhetoric was applied so you can breed concern and you may hatred out of Bosnian Muslims and you will Bosnian Croats together with the result from exacerbating ethnic departments and you will tensions within the BiH."


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Japanese Waterfall Kumano Nachi Taisha
Size: 24 inches by 20 inches.
Medium: Acrylic on stretched canvas.
"Ever since I was 9 I have been enamored with Japanese cooking, and around that age, I started watching Godzilla films. They depicted life in Japan, so I was exposed to architecture, culture, and a society that was very different from my own at a very young age. When I started attending university, I joined the Japanese Culture Society, and quickly became a very active member, meeting several Japanese transfer students. Working together with them made me realize how different their experiences were from my own, and that just intrigues me greatly. So my next step would be to visit for myself." -John D.

subset: commoncrawl


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Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/14521
The Vallecas Project: A Cohort to Identify Early Markers and Mechanisms of Alzheimer's Disease
Olazarán, Javier | Valentí, Meritxell | Frades, Belén | Zea-Sevilla, María Ascensión | Ávila-Villanueva, Marina | Fernández-Blázquez, Miguel Ángel | Calero, Miguel ISCIII | Dobato, José Luis | Hernández-Tamames, Juan Antonio | León-Salas, Beatriz | Agüera-Ortiz, Luis | López-Álvarez, Jorge | Larrañaga, Pedro | Bielza, Concha | Álvarez-Linera, Juan | Martínez-Martín, Pablo ISCIII
Date issued
Front Aging Neurosci. 2015 Sep 30;7:181.
Document type
journal article
Introduction: Alzheimer's disease (AD) is a major threat for the well-being of an increasingly aged world population. The physiopathological mechanisms of late-onset AD are multiple, possibly heterogeneous, and not well understood. Different combinations of variables from several domains (i.e., clinical, neuropsychological, structural, and biochemical markers) may predict dementia conversion, according to distinct physiopathological pathways, in different groups of subjects. Methods: We launched the Vallecas Project (VP), a cohort study of non-demented people aged 70-85, to characterize the social, clinical, neuropsychological, structural, and biochemical underpinnings of AD inception. Given the exploratory nature of the VP, multidimensional and machine learning techniques will be applied, in addition to the traditional multivariate statistical methods. Results: A total of 1169 subjects were recruited between October 2011 and December 2013. Mean age was 74.4 years (SD 3.9), 63.5% of the subjects were women, and 17.9% of the subjects were carriers of at least one ε4 allele of the apolipoprotein E gene. Cognitive diagnoses at inclusion were as follows: normal cognition 93.0% and mild cognitive impairment (MCI) 7.0% (3.1% amnestic MCI, 0.1% non-amnestic MCI, 3.8% mixed MCI). Blood samples were obtained and stored for future determinations in 99.9% of the subjects and 3T magnetic resonance imaging study was conducted in 89.9% of the volunteers. The cohort is being followed up annually for 4 years after the baseline. Conclusion: We have established a valuable homogeneous single-center cohort which, by identifying groups of variables associated with high risk of MCI or dementia conversion, should help to clarify the early physiopathological mechanisms of AD and should provide avenues for prompt diagnosis and AD prevention.
Online version


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Urban Farm Collection
Pumpable Buttercream Tallow Body Oil
Pumpable Buttercream Tallow Body Oil
4 fl oz glass pump bottle
Try my new formula for PUMPABLE tallow. This makes application SO MUCH easier than having to scoop out of the jar. I've also formulated the ratios to make it less greasy. You'll be amazed at how quickly it absorbs into your skin!
Pure, healing dessert for your skin. This lightweight, silky tallow blend spreads beautifully and smells truly divine. Like a freshly-baked vanilla cake! Grass-fed tallow, emu oil, grass-fed ghee, cocoa butter, and organic jojoba are vitamin-rich and deeply moisturizing, while protective Vitamin E helps to fight free radicals and signs of aging. Our vitamin-rich ingredients are chosen with care from sources we trust, so your skin can be restored, protected, and nourished.
To use: work into skin, wherever you need some love and healing. A little goes a long way! Best used within 6 months.
Ingredients: Grass-fed suet tallow, Grass-fed ghee, Australian emu oil, Cold pressed Jojoba oil*, Cocoa butter*, Vitamin E oil*, local beeswax, and Vanilla botanical extract
The Benefits
Grass-fed Tallow is rich in the same types of lipids found in youthful, vibrant skin and is packed full of Vitamins A, D, E, and K. The fatty acids in tallow are more bioavailable than plant based oils because tallow is much closer in molecular structure to the oils our own skin produces. Tallow is non-comedogenic, locking in moisture without clogging your pores.
Australian Emu Oil is refined from the fat of emu birds, native to Australia. Traditionally used for sun protection among Australian aboriginals, Emu oil may provide some SPF and is beneficial for healing sunburns. Emu oil deeply hydrates the skin by helping to prevent water loss, and helps heal wounds and blemishes. It is a potent anti-inflammatory, rich in anti-oxidative properties to nourish the skin, slow down wrinkle formation, and ease other aspects of the aging process. The anti-inflammatory aspects of emu oil may offer some relief for arthritic pain.
Ghee provides the deep, softening moisture that your skin craves. With unique antioxidant and radiance-boosting properties, ghee is chock-full of fatty acids and butyrate, making it an ideal ingredient to moisturize sensitive, inflammation-prone skin. Ghee is non-comedogenic and has been used in skincare for thousands of years. Ghee is said to soften and hydrate skin, provide a natural glow, lighten dark spots, repair damaged skin, reduce dark circles and heal minor wounds.
Jojoba oil Low PUFA Jojoba Oil has lovely anti-inflammatory properties which help to tame chaffing and chapping, reduce redness caused by drying, ease the effects of eczema and rosacea, and keep skin calm and comfortable. The Vitamin E and B-complex vitamins in the Jojoba Oil also help in skin repair. Jojoba is similar to our own skin's sebum, making it bio-adaptable and easy to absorb without clogging pores.
Vitamin E oil is antioxidant-rich and can help improve blood circulation. Its moisturizing properties can make your skin look firm and youthful, as well as helping to slow down the skin aging process. The combination of vitamin A (in things like beeswax) and vitamin E may help in removing acne-causing bacteria. Vitamin E can also reduce hyperpigmentation and scarring.
Cacao Butter is naturally high in fatty acids. This creates a protective barrier that holds in moisture, improves elasticity, and prevents your skin from drying. In addition, it's high in antioxidants that repair and protect against free radical damage. It makes a wonderfully nourishing addition to your skincare routine!
Beeswax helps lock in moisture and can act as a protective barrier for your skin. It is rich in Vitamin A and can help protect your skin from environmental damage. Beeswax also has anti-inflammatory, antibacterial, antiseptic and anti-fungal properties and has been known to help heal acne, eczema, psoriasis, and stretch marks.
Vanilla botanical extract smells divine and gives this body oil a cake-like aroma!
Soaks into my skin beautifully and smells like vanilla Heaven. Also my order shipped lightning fast and was packaged with care.
I threw everything else out. This is the holy grail. I'm sure of it. The smell is heavenly. I recently had a bad allergy attack and was blowing my nose sooo many times leaving me with a flaky nostril. This product nourished my skin and helped it heal within a day! Truly the only product I use on my skin.
It's also the perfect consistency to use with a gua sha.
If you worry about the tallow hardening and not pumping, just let it sit in a bowl of warm water for a few moments and you'll be good to go again. Loving the fresh nature made ingredients!
Love this clean, hydrating skin body oil. Instantly calms and soothes skin and moisturizes all day.
I love the fact that this is pumpable tallow, with 4 kids, it's made bath time routine so much easier, as the more independent kids can spread this deliciousness instead of me having to scoop out from a jar for everyone. Did I say it smells absolutely delicious 🤗
I absolutely LOVE this body oil! It smells so yummy like vanilla cake! Also, it soaks in quickly so even though it's a natural moisturizer, it does my mess up the bedding if I put it on before sleep. Favorite!


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Abujapress reports that a pub owner, who was popularly called Iya Bisola, in the Ikirun area of Osun State has died.
She was found dead inside her house.
Details of what led to the incident were still sketchy as of press time, but security sources said the remains of the deceased were found in her house located around Oke Glo Area in Ikirun.
Some residents of the area, who spoke on condition of anonymity, noted that marks were seen around her neck, which, according to them, suggested that she must have been strangled.
A resident, who preferred to be identified as Jide, said since the deceased's shop, located along Station Road in Ikirun, was not close to her residence, people in the neighbourhood where she lived hardly saw her as she spent evenings attending to her patrons.
He called for a thorough investigation into the matter while asking for the reinforcement of security personnel in the town.
The spokesperson for the state police command, Yemisi Opalola, could not be reached through her mobile phone on Friday. But the spokesperson for the Nigeria Security and Civil Defence Corps in the state, Kehinde Adeleke, said in an interview that officers of the command visited the scene before the corpse was evacuated.
She added, "A popular beer parlour vendor, called Iya Bisola, at Station Road, Ikirun, was allegedly strangled to death by unknown person(s).
"Though the reason for her assassination is yet to be unravelled, our personnel visited the scene of the incident at Oke Glo, Ikirun, before the corpse was evacuated."


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From UPSC perspective, the following things are important :
Prelims level : Mawsynram
Mains level : Not Much
A recent study that looked at the rainfall pattern in the past 119 years found a decreasing trend at Cherrapunji and nearby areas.
Try this PYQ:
Q."Climate is extreme, rainfall is scanty and the people used to be nomadic herders." The above statement best describes which of the following regions?
(a) African Savannah
(b) Central Asian Steppe
(c) North American Prairie
(d) Siberian Tundra
- Mawsynram is a town in the East Khasi Hills district of Meghalaya state in northeastern India, 60.9 kilometres from Shillong.
- Mawsynram receives the highest rainfall in India.
- It is reportedly the wettest place on Earth, with an average annual rainfall of 11,872mm but that claim is disputed.
- According to the Guinness Book of World Records, Mawsynram received 26,000 millimetres (1,000 in) of rainfall in 1985.
Why it rain highest in Mawsynram?
- Because of the uneven relief of India due to the presence of a number of hill ranges, the monsoon is not able to shed its moisture evenly over India.
- Windward sides receive more rainfall and leeward sides receive less rainfall.
- Mawsynram lies in the funnel-shaped depression caused by the Khasi range in Meghalaya.
- The Bay of Bengal branch of monsoons is trapped in it and causes heavy rainfall.
Decreasing rainfall trends
- The research analysed daily rain gauge measurements during 1901–2019 and noted that the changes in the Indian Ocean temperature have a huge effect on the rainfall in the region.
- There was a reduction in the vegetation area in northeast India in the past two decades, implying that human influence also plays an important role in the changing rainfall patterns.
- The traditional way of cultivation known as Jhum cultivation or shifting cultivation is now decreased and being replaced by other methods.
- Also, previous studies have noted there is sizable deforestation in the region.
Get an IAS/IPS ranker as your 1: 1 personal mentor for UPSC 2024


text:
Footage has been shared online showing the moment a swimmer came face to face with a huge basking shark.
The man was swimming off the coast of Malaga, Spain, when the monstrous animal glided past him, with its fin peeking out of the water.
According to reports, this most recent sighting (22 May) of the the plankton-eating basking shark was the third in less than a month in the country's southern waters.
Experts who have seen the footage believe that the shark was about 20ft long.
It's understood that the video was captured from a boat the swimmer is thought to have jumped from in order to get a closer look at the animal.
And though the shark is said to be harmless to humans, local authorities have warned kayakers and other sports enthusiasts to be vigilant and not to approach them.
This comes after another shark of the same sort described as being more than 26ft long was spotted last weekend (16/17 May) off La Mamola Beach.
And at the beginning of the month, a smaller basking shark was also spotted off the nearby resort of Calahonda on the Costa Tropical. That one was much smaller at around 10 feet.
Further north, off Sant Pol beach near Barcelona, members of Spain's Paralympic swimming team were filmed out-sprinting two suspected blue sharks.
Ariel Schrenck was part of the Spanish team that took part in last year's World Para Swimming Allianz Championships in London, and was training at the time.
Speaking to local media about the incident, he said: "My mum started to shout like a crazy woman that there were sharks in the water.
"At that moment my body started panicking terribly and I started swimming like a madman. I think I was 100 meters from the shore. I think they were the 100 metres where I most put my heart and soul into swimming for my life.
"I'm not in top shape and I almost died sprinting to the shore."
The sharks the 19-year-old out-swam are thought to be tintoreras or blue sharks, which have been blamed for several attacks on holidaymakers in the past, including one in Elche near Alicante in July 2016. So Ariel may have been lucky to get away.
The 40-year-old victim in the 2016 incident was rushed to hospital and given stitches to a wound in his hand.
Featured Image Credit: SolarpixTopics: Interesting, Spain, shark


text: Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content +++ KEY POINTS ++ KEY POINTS Hemorrhage from pelvic injuries is frequently underestimated, leading to delayed diagnosis and treatment. Pelvic ring injuries are commonly associated with other significant injuries resulting in major morbidity and mortality. Initial management of pelvic injuries requires hemorrhage control and volume resuscitation. Resuscitative stabilization of the pelvis using a binder is a key element in the initial control of hemorrhage from pelvic fractures. Rapid control of pelvic bleeding followed by mechanical stabilization of the pelvis yields the best outcomes. The mechanism of injury is important in predicting the type and severity of extremity injuries. Extremity fractures, though frequently not life threatening, require accurate diagnosis and appropriate management to prevent significant disability and morbidity. Complications of extremity injuries, such as compartment syndrome and neurovascular compromise, can best be detected by a high index of suspicion, serial assessment, and institution of appropriate preventive measures. +++ INTRODUCTION ++ Patients sustaining major pelvic and extremity trauma are frequently managed in the ICU setting. These patients may present with significant hemodynamic and physiologic instability owing to their associated injuries, and this can be compounded by inadequate resuscitation resulting from underestimation of the volume of blood loss associated with such injuries. The following information is provided to assist the intensivist in understanding pelvic ring and extremity injuries, thus allowing early diagnosis with prompt and appropriate management aimed at preventing major morbidity and mortality. +++ PHASES OF CARE FOR ORTHOPEDIC INJURIES IN THE MULTITRAUMA PATIENT ++ The assessment and treatment of orthopedic injuries in the multitrauma patient can best be divided into three phases of care: resuscitation, provisional skeletal stabilization, and definitive treatment. The progression from one phase to the next is based on the hemodynamic and physiologic status within the context of mechanical skeletal stability. ++ There are advantages to treating certain orthopedic injuries, such as femoral shaft fractures, as early as possible since the mechanical instability of the fracture increases the risk of complications like fat embolism syndrome (FES), which carry a high mortality rate. However, with improved ability to operatively treat complex orthopedic injuries to obtain better functional outcomes earlier, there are situations where doing too much too early may actually lead to more significant systemic complications. ++ There is an acute systemic inflammatory response associated with major trauma, which has been related to multiorgan system failure (MOSF) and ARDS, described as the "first hit." A subsequent systemic stress or "second hit" may trigger an additional inflammatory response, leading to a higher likelihood of MOSF or ARDS and an increased risk of mortality. It is theorized that a major surgical intervention prior to full resuscitation may be such a "second hit."1 Certain systemic indicators are useful in determining whether a prolonged surgical reconstruction is likely to result in further systemic compromise. ++ A protocol for "Early Appropriate Care" demonstrated lower pulmonary and overall complication rates ... Your Access profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click 'Continue' to continue the affiliation switch, otherwise click 'Cancel' to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free a profile for additional features.


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Turkey's lira dropped for the eighth consecutive day in the biggest sell-off since a currency crisis peaked in December as investors fretted over the impact of the war in neighbouring Ukraine on the country's import-dependent economy.
The lira dropped by 1.6 percent to 14.87 per dollar on Thursday. That was the lowest level since President Recep Tayyip Erdogan announced a deposit scheme linking the lira to the dollar in late December in an attempt to arrest a freefall in the currency.
The war in Ukraine has left Turkey's economy exposed to surging energy prices. The rising price of commodities plus loose monetary policy – Erdogan has ordered the central bank to slash interest rates – has sent inflation soaring to 54.4 percent. That is the highest level of any major economy or emerging market. Economists say inflation may hit as high as 70 percent in the coming months.
"We have been caught in one of the worst shocks that could happen to us, with a fragile economy. We are not at war, but we are bombarded from five channels: foreign trade, tourism, risk premium, energy, food prices," Hakan Kara, a former chief economist for Turkey's central bank, said on Twitter.
Turkey's natural gas import bill is expected to double to $40 billion this year, pressuring government and central bank finances, Reuters reported on Thursday. That cost compares with the central bank's $18 billion in net official foreign exchange reserves.
The country's trade deficit more than doubled to $8.1 billion in February, led by a 45.6 percent annual increase in imports to $28.1 billion. Exports rose by 25.4 percent to $20 billion. The current account deficit is expected to widen to $7.5 billion in January, the biggest gap in four years, according to a Reuters poll published this week. The data is due tomorrow.
Turkey needs to fund any deficit in its current account with foreign currency revenue such as tourism income or investment or risk more losses for the lira. But the war in Ukraine is threatening a slump in visitors from Russia and Ukraine, both of which provided millions of tourists and billions of dollars in revenue last year. Russia is the country's biggest provider of visitors.
The Turkish authorities are growing more alarmed each day that the fallout from the war in Ukraine may scupper Erdogan's economic programme, which is focused on attaining current account surpluses and keeping interest rates low, Reuters said citing interviews with four unidentified Turkish officials. The central bank cut rates to 14 percent from 19 percent in the final four months of last year on the president's orders, sparking the sell-off in the lira.
The lira lost 44 percent of its value against the dollar in 2021.


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Tobey Maguire details like Fan Mail Address, Phone Number, Autograph request, and mailing address are shared here. Are you a follower of Tobey Maguire? Are you searching on search engines for How to contact Tobey Maguire? What is the phone number, Texting number, contact number of Tobey Maguire's Manager, or his personal contact number? What is the email id of Tobey Maguire?
Are you looking for what is the official fan mail address of Tobey Maguire? Who are Tobey Maguire's contact agency and manager? To reach him, you'll need to find his public Facebook, Twitter, and Instagram profiles. Tobey Maguire's fan mail address, contact details, and authorized social media profiles are all included in this section.
By 2022, Tobey Maguire will have turned 47 years old, having been born on June 27, 1975. He grew up in a Christian home of modest means in Santa Monica, California.
Both he and his wife are atheists. He was unable to finish high school and now he has no formal education. Later, he joined the Young Actors Space and graduated with a certificate in acting. Even as a young child, he preferred performing and other extracurricular activities to schoolwork.
He is the youngest of five siblings. His sister's name is Sara Maguire, and his brothers are Weston Epp, Jopaul Epp, Vincent Maguire Jr., and Timothy Maguire. constructed By 2020, the couple's separation was finalized. In addition to Jennifer, he has been linked to Rashida Jones, Nicole Richie, Kristen Dunst, Demi Moore, and Christina Aguilera.
Tobey Maguire is a famous American actor, and he is widely recognized for his portrayal of Peter Parker/Spider-Man in the three film adaptations of the Marvel Comics superhero. Easily one of the most famous actors in the industry Besides acting, Maguire has also dabbled with film production. Since he was a kid, he's followed his mother's dream and has been attending theatre school to prepare for a career in acting. He got his start on TV but eventually found film roles that allowed him to show off his talents. During the beginning of his career, he was cast almost exclusively in the roles of adolescent protagonists.
Unfortunately, Maguire's career was derailed by alcoholism at a pivotal time. Due to his alcoholism, he had to bail out of a movie in which he was set to star. After making a comeback to acting, he was warmly received by the film industry, and he finally broke through with his role as the title character in Sam Raimi's 'Spider-Man' in 2002. Maguire appeared in the equally popular 'Spider-Man' sequels after the first film's massive success. Subsequently, he was featured in a number of films that were both critically and commercially successful.
Tobey Maguire's parents, Vincent Maguire and Wendy Brown welcomed their son, Tobias Vincent Maguire, on June 27, 1975, in Santa Monica, California, United States. Maguire's father was a chef and construction worker, and his mother started out as a secretary before switching careers to become a producer and screenwriter. Tobey Maguire's parents weren't married when he was born, but they eventually tied the knot and split up in 1977. Maguire's parents' divorce meant he spent his formative years in several locations.
Earlier in life, Tobey Maguire envisioned himself in the kitchen. He decided to pursue acting when his mother provided him with money to enrol in a screenwriting class. He did not graduate from high school, but in 2000 he received a diploma for "General Educational Development." Tobey Maguire got his acting start on television, appearing in guest appearances on shows including "Roseanne" and "Blossom." In 1989's "The Wizard," he made his film debut in a small, voiceless role. The sitcom 'Great Scott,' on which he was set to star as the male protagonist, was cancelled in 1992. It was in 1993 that Tobey Maguire appeared opposite Robert De Niro and Leonardo di Caprio in the film This Boy's Life. His character is a young man who is friendly with Leonardo di Caprio's main character.
Tobey Maguire was set to star in 'Empire Records' in 1995, but the actor had to drop out halfway through filming due to drinking. After completing a stint in "Alcoholics Anonymous," he made a comeback to acting in the short film "Duke of Groove." Later, he appeared in films including Ang Lee's The Ice Storm and Woody Allen's Deconstructing Harry.
Maguire made a film appearance in 'Fear and Loathing in Las Vegas' in 1998. Soon after, he starred in more critically acclaimed films like "The Cider House Rules" and "Wonder Boys." As a result of his roles in these films, Maguire gained a reputation as an actor who could play virtually any type of character.
The part of Spider-Man in the 2002 film of the same name was the biggest break of his career. Both "Spider-Man 2" (2004) and "Spider-Man 3" (2007), sequels to the original film, were smash hits. The movie did quite well at the box office, and Maguire received excellent marks for his performance. Tobey Maguire made his directorial debut with the 2002 picture 25th Hour. In addition to "Seabiscuit," he produced "Whatever We Do". He had a negative role in the 2006 film The Good German. After that, he had a small part opposite Robert Downey Jr. in the film "Tropic Thunder".
Next, Tobey Maguire starred alongside Jake Gyllenhaal in the 2009 picture Brothers. Maguire was praised for his portrayal of a battlefield prisoner. Tobey Maguire is a well-known actor who has starred in a number of critically acclaimed films. His role as Spider-Man in Sam Raimi's 'Spider-Man' trilogy is widely regarded as his finest acting achievement.
Tobey Maguire and jewellery designer Jennifer Meyer wed in 2007. They had been together for four years at that point. Ruby Sweetheart Maguire, their daughter, was born a year before they tied the knot. In 2009, they had a son—their second child. Maguire and Meyer separated the following year (2017) after announcing their split in October 2016.
Tobey Maguire is the stage and screen name of American actor and producer Tobias Vincent Maguire. Tobey Maguire's wealth in 2022 is estimated to reach $75 million. He has been working in this field since 1989. Now that the critically acclaimed Spider-Man: No Way Home has been published, he is getting a lot of attention for his portrayal of the web-slinger.
Tobey Maguire Contact Information
Here you can find his contact data, including his fan mail address, address details, email id, residential address, house address, place of birth, phone number, contact number, email id, physical address, booking agent data, and manager/secretary contact information.
Fan Mail Address:
Tobey Maguire
Entertainment 360
10100 Santa Monica Blvd
Suite 2300
Los Angeles, CA 90067
Address Information:
Entertainment 360
(Talent Management Company)
10100 Santa Monica Blvd
Suite 2300
Los Angeles, CA 90067
He's up for two Saturn Awards, and one of them is Best Actor. Maguire co-produced Good People in 2013 with his own production company, Material Pictures, which he established in 2012. His portrayal of Bobby Fischer in the 2014 play Pawn Sacrifice was a collaborative effort that he produced and acted in.
After that, he appeared in a string of films that garnered praise from both moviegoers and critics. When Tobey Maguire first entered the job, he planned to become a chef. He decided to get into acting after watching his mother have a successful career in screenwriting, which provided him with the means to finish his training. Even though he did not meet the criteria for a high school graduation, he was granted a certificate of general education in the year 2000. Tobey Maguire got his start in show business on television, with roles in shows including "Roseanne" and "Blossom." His acting career began with a little cameo in the 1989 film The Wizard.
Originally, he was cast as the male lead for the 1992 episode of "Great Scott," but the production was cancelled. Tobey Maguire, Robert De Niro, and Leonardo di Caprio starred in the 1993 film This Boy's Life. Maguire was cast as a young man named Danny, who would become Leonardo di Caprio's character's companion in the movie. The film starred both Leonardos, Leonardos Di Niro, and Di Caprio.
(1)Full Name: Tobias Vincent Maguire
(2)Born: June 27, 1975
(3)Father: Vincent Maguire
(4)Mother: Wendy (née Brown)
(5)Brother: Vincent Maguire Jr. (Half-Brother)
(6)Spouse: Jennifer Meyer (m. 2007–2017)
(7)Occupation: Actor and Film Producer
(8)Famous As Actor and Film Producer
(9)Birth Sign: Cancer
(10)Nationality: American
(11)Height: 5 feet 8 inches
(12)Religion: Judaism
(13)School: high school
(14)College/University: NA
(15)Educational Qualifications: Graduate
(16)Hometown: Santa Monica, California, United States
(17)Address: Santa Monica, California, United States
(18)Hobbies: Acting
(19)Contact Number: (310) 272-7000
(20)Email ID: NA
(21)Facebook: https://www.facebook.com/TheTobeyMaguire
(22)Twitter: https://twitter.com/TobeyMaguire
Because of his alcoholism, Tobey Maguire had to leave the set of the 1995 film Empire Records while production was still underway, despite the fact that he had a prominent role in the movie. The movie ended up becoming a hit. After beating his alcoholism, he joined "Alcoholics Anonymous" and made his acting debut in the short film "Duke of Groove." He oversaw the production of the Woody Allen and Ang Lee flicks "Deconstruction Harry" and "The Ice Storm." He oversaw production on both of these endeavours.
It was so financially successful that it spawned two follow-ups, "Spider-Man 2" in 2004 and "Spider-Man 3" in 2007, all of which were released in theatres. Moviegoers and critics alike applauded Maguire's performances, which they credited with helping the films receive acclaim.
With the release of the film he both acted in and directed in 2002, Tobey Maguire entered the world of cinema. Two other films, "Whatever we do" (2003) and "Seabiscuit" (2007), have been produced by him since then (2005). In the 2006 film "The Good German," he played a role that was not in the protagonist's best interest. He co-starred with Robert Downey Jr. in the next year's film "Tropic Thunder" (2008). Tobey Maguire's breakout role in the film "Brothers," which also starred Jake Gyllenhaal, catapulted him to stardom.
There was a 2009 premiere for the movie. Maguire continued to receive praise for his work even when he was being held as a prisoner of war. In 2013, he co-starred alongside Leonardo di Caprio in Baz Luhrmann's "The Great Gatsby." The next year, in 2014, he starred in "Pawn Sacrifice," in which he portrayed legendary chess player Bobby Fischer. Beginning in 2015, he has focused almost entirely on developing his career as a producer. Released in 2017, the animated picture "The Boss Baby" featured his voice acting skills. Tobey Maguire has been in several films, with mixed reviews of his performances depending on the quality of the movie. The Spider-Man films directed by Sam Raimi remain his most recognizable body of work.
After that, he starred in a string of critically acclaimed films like "The Cider House Rules" and "Wonder Boys." Maguire became more well-known as a result of these films, and he demonstrated his acting skills by taking on a wide variety of roles. In 2002, he was granted a once-in-a-lifetime opportunity when he was chosen to play Spider-Man in a film adaptation of the comic book of the same name. He got to be the movie's main attraction thanks to this part. Since the film was so successful, two more instalments—"Spider-Man 2," released in 2004, and "Spider-Man 3," published in 2007,—were subsequently made and released.
Fans of the flicks complimented Maguire's acting skills. According to certain sources, In this case, the citation is required Tobey Maguire's first sizable monetary investment in his career came from his role as producer on the film "25th Hour." After that, he directed two further films, the first in 2002 titled "Whatever We Do" and the second in 2006 titled "Seabiscuit." These two movies followed his initial triumph. (2003). In the 2006 film "The Good German," he appeared in a less-than-flattering role. After that, in 2008, he had a major role in the film "Tropic Thunder," co-starring Robert Downey Jr.
Read Also: Louis Tomlinson Fan Mail Address, Phone Number, Texting Number and Contact Details


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Smitten with my canvas tote from Dos Marias PH. It fits all my folders and documents for running errands and all my swim gear for when I need to unwind by doing a few laps.
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text: Anicia May found herself drawn in by the need to write from a young age. This spanned from poems and stories as a child, to classically inspired piano pieces as a teenager, and finally songwriting on guitar in her early 20s. Loath to ever describe herself as or pursue the career of a musician, Anicia obtained a degree and forged a career in law: it was more stable than music, and to be honest, she had always wondered whether she was even very good at music anyway. In 2021, Anicia picked up her guitar and played some of her songs for established producer, jayteehazard, who she has known for many years. jayteehazard quickly teamed up with Anicia to produce 'Florence', Anicia's debut single. This sparked a collaboration, and a flurry of songwriting from Anicia. After a sputtering trajectory, Anicia finally has a collection of darkly lyrical folk-inspired songs that she is proud of and ready to release.


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Rating: 2.75 stars
Buy Link: Amazon | iBooks | Amazon UK
Length: Novel
Bash is good at what he does. He's a killer, a hunter, a fighter, and a hero who — with the backing of Fortress — rescues civilians from war zones, fights terrorists, and saves lives. He's ruthless and selfless, and when someone needs to stay behind to distract the terrorists and let an American family escape, Bash doesn't give anyone else a chance to volunteer. His act of bravery leaves him in prison, mildly beaten, and exchanging pleasantries with Sean, a fellow prisoner who is a pediatrician with face of a model and an air of innocence.
When Sean asks to be rescued, Bash has no choice but to say yes. How could he leave this man behind? Even if Sean is the grandson of Bash's captor, King Faisal, and next in line for the throne of Akkadia. However, Sean has no desire to be a crown prince, certainly not in a country where being gay is a crime and where women are treated like property. He'd never do that to his sister, or to himself.
What begins as an escape into a whirlwind ends up as a whirlwind romance between the prince and his bodyguard, and a mystery generations in the making.
This book opens with Bash taking down Arab terrorists before being captured and tortured and tossed in a cell. There he meets Sean who, though he has spent all of his life in England and is an English citizen, has a voice that Bash notes carries "desert sands and palm trees under a star-filled sky" that, along with his dark, olive skin, tells Bash that Sean is probably of Middle Eastern descent. There's a lot of subtle commentary — how overly obsequious the Akkadian servants and guards are to their Crown Prince, how badly gay people and women are treated — that, rather than add color or texture to the world, comes across as stereotyped and heavily biased.
Sadly, all of that is more prominent than the romance between Bash and Sean. Bash is, and has always been, the sort of man who would take on bullies. Not to throw his weight around, but because it's the right thing to do. He has a great deal of insecurity about relationships as his father abandoned him when he was young, and many of his actions towards Sean feel controlling and testing. For example, knowing their rescue is just around the corner, Bash doesn't tell Sean. Instead, he sets up a choice: Follow me into the desert with limited water, deadly heat, and a risk of death and capture … or stay behind where you're marginally safer and may be rescued by workers (who might turn you in to the king, but might not.) Either way, I'm headed into the dangerous waste by myself, alone, and injured, if you don't come with me. It isn't until Sean protests that he'd follow Bash anywhere that Bash gets to laugh and tell Sean that it's all just a joke, and rescue's on its way.
Bash needs control, and he needs to feel in charge, but I didn't enjoy how he handled the situation. Sean, for his part, has been in a prison for four months, afraid for his life, and that's even without revealing to his grandfather that he's not only refusing to accept the title of crown prince, marry, and provide some great-grandchildren, he's also gay. Bash is Sean's rescuer, his hero, and is it any wonder that Sean clings to Bash? And then they're rescued and their adrenaline-fueled fuck buddy status seems to go to a deep and abiding love over the days they're both safe and secure within Fortress. Unfortunately, especially for a romance novel, none of that is in the book. It's just assumed rather than shown.
The plot of assassinations, hidden heirs, and playing prince are done well enough. Bash's ego is on full display as is Sean's dithering, and while the pair proclaim their love every now and then, I just didn't feel any chemistry between them. The writing is serviceable, though there are a few copy errors, such as a missing comma, spacing issues, and typos such as these:
Bash raised a brow, wanting to know Bash's opinion.
The one saving grace in all this was that Sean hadn't been uninjured.
All in all, I personally didn't care for this book and I do not think I'll be continuing the series.


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Step One Clothing (ASX: STP) nosedived almost -40% to $1.46 as the market opened amid a potential GST credit overclaim and logistics issues.
Step One, a direct-to-consumer pure online retailer for men's underwear, made its ASX debut in November at an offer price of $1.53. The company's stock closed at $2.70 on its first day of listing.
Step One flagged a potential overclaim of GST credits relating to one of its foreign suppliers.
The company anticipates the overclaim to take a $0.1m hit on FY20 after tax earnings, $0.9m on FY21 and $1.1m on FY22.
To add some perspective, Step One achieved $2.29m net profit in FY20, $7.7m in FY21 and forecasts $10.5m in FY22.
It is understood that the adjustments will be reflected as 'higher advertising costs'.
Step One encountered logistics challenges in both the UK and Australia during the Black Friday trading period, increasing customer delivery times and reducing media spend effectiveness.
The backlog has now been cleared, however, the company has withheld several pre-Christmas campaigns and new launches, including the release of a women's range.
The company expects first-half revenue of approximately $36-$39m, a 12% increase on the previous period.
Despite the sharp selloff, Step One said it expects sales revenue to grow 21-25% in FY22, well above prospectus forecasts of 19.9%.
Step One shares plunged -37.9% to $1.46 within the first few minutes of trade.
By noon, the losses recovered to -28.9% or $1.67.
From an intraday perspective, the share price bounced 14.4% off lows, on the back of massive volume with 5.4m shares trading hands compared to a 20-day average of around 640,000.
Step One has a short but sweet track record of growth, achieving compound annual revenue growth from FY19 to FY21 of over 183%.
Australia currently represents approximately 66% of total customers by revenue with the UK growing strongly since its launch in 2020.
Growth drivers in FY22 include a full launch in the US and primary testing in other 'high potential markets'.
Get the latest news and insights direct to your inbox


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35m CUSTOM ADMIRAL SUPERYACHT Admiral Yachts | From EUR€ 90,000 /wk
35m CUSTOM ADMIRAL SUPERYACHT from Admiral Yachts was built in 2014 and features an exterior design by renowned designer Luca Dini. At 35.6m/116.10ft there is plenty of space on board for hosting special events or for extended cruising in comfort with family and friends. The interior design skillfully manipulates light and texture to create a sophisticated modern living environment that feels like a tranquil haven, even in the heart of bustling cities. The accommodation sleeps up to nine guests across four en-suite cabins, with a crew of five to take care of every little detail.
NOTABLE FEATURES OF 35m CUSTOM ADMIRAL SUPERYACHT: ~Flybridge bar ~Stately modern interiors ~Cinema/children's playroom ~Choice of dining areas ~Range of 2,700 nautical miles ~Air conditioning ~Wi-Fi
The main deck aft is a sheltered environment ideal for outdoor lounging and alfresco dining. There is a sofa along the stern, and elevated table and non-fixed chairs, and two stairways lead down to the swim platform for easy access to the water. Side walkways lead past the main salon to the foredeck, where guests can settle onto the sofa and enjoy the sunshine in privacy.
The flybridge aft is a desirable social space with a sofa/sunbed along the stern, and a coffee table and a pair of sun loungers complete the space. The amidships section is shaded by the hardtop, under which there is a bar and casual alfresco dining area, with a fold-down TV concealed in the ceiling for outdoor entertainment. The forward section has a stairway leading down into the raised pilothouse for guest convenience.
The lower deck hosts the guest and crew accommodation, with the main deck dedicated to group entertainment and dining.
There is a cinema room/children's play room in addition to the combined formal dining area and main salon, where up to eight guests can enjoy a meal in the ambient air-conditioned surroundings with a starboard door leading out onto the side walkway.
35m CUSTOM ADMIRAL SUPERYACHT Specifications
Type/Year: | Admiral Yachts/2014 |
Refit: | |
Beam: | 6.80m (22' 4") |
L.O.A.: | 35.60m (116' 10") |
Crew: | 5 |
Guests: | 9 |
Max Speed: | 15.5 knots |
Cabins: | 4 |
Engines: | 2x MAN 1.400 HP |
Cruise Speed: | 14 knots |
More Yacht Info: | family friendly yachts, Latest New Charter Yachts, yachts with at anchor stabilisers |
Builder/Designer: | Admiral |
Locations: | Western Mediterranean, THE MEDITERRANEAN, Directory |
The salon has TV entertainment as well as the cinema room, and the layout places a sofa/lounger to port along with a coffee table, and a smaller sofa lines the starboard side. The raised pilothouse above gives convenient access through to the flybridge.
Twin MAN engines of 1.400 HP give a top speed of 15.5 knots, a cruising speed of 14 knots and a range of 2,700 nautical miles.
Yacht Charter Accommodation
The accommodation sleeps a maximum of 9 guests over 4 en-suite cabins: 1 Master suite, 1 VIP stateroom and 2 twin cabins, one of which has a Pullman berth. The Master suite provides a king-sized bed, a widescreen TV, desk/vanity, ample wardrobe space and an en-suite bathroom with a sink, toilet and shower. The VIP stateroom has a queen-sized bed, a widescreen TV, plenty of storage and an en-suite bathroom with a sink, toilet and shower. The twin cabins both have two single beds, a widescreen TV, plenty of storage and an en-suite bathroom with a sink, toilet and shower. An expert crew of 5 will ensure that all guests receive the first-class service throughout their time onboard.
Charter Amenities and Extras
We do have available further amenity, owner and price information for the 35.60m (116' 10") yacht 35m CUSTOM ADMIRAL SUPERYACHT, so please enquire for more information.
Charter Yacht Disclaimer
This document is not contractual. The yacht charters and their particulars displayed in the results above are displayed in good faith and whilst believed to be correct are not guaranteed. CharterWorld Limited does not warrant or assume any legal liability or responsibility for the accuracy, completeness, or usefulness of any information and/or images displayed. All information is subject to change without notice and is without warrantee. A professional CharterWorld yacht charter consultant will discuss each charter during your charter selection process. Starting prices are shown in a range of currencies for a one-week charter, unless otherwise marked. Exact pricing and other details will be confirmed on the particular charter contract. Just follow the "reserve this yacht charter" link for your chosen yacht charter or contact us and someone from the CharterWorld team will be in touch shortly.
35m CUSTOM ADMIRAL SUPERYACHT Enquiry
"In fifty years the ADMIRAL brand has became a landmark in international yachting for yachts, super yachts and mega yachts, synonymous with style, creativity, quality and design." - Admiral Yachts


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You've probably been asking yourself, "What's the difference between a short bed and a standard one?" Usually, the answer is that the two are almost identical, though some differences may exist, too. A short bed is typically ufa24time around five feet eight inches long. Long beds are about eight feet long. However, the difference in length is not as pronounced as you might think. You might be more comfortable with a standard long bed, if you prefer that style.
When you're deciding between a standard short bed and a long one, it's important to consider how much space you need. A standard bed is the size you'll need for work-related purposes and the weekend. However, if you're looking for extra cargo space, a long bed truck is ideal for you. You can choose sbobetauto between several models of this model, including Ford's F150 long bed.
A standard short bed is about five feet long and 6.5 feet long. This length is ideal for hauling small items and yard waste. Alternatively, you can choose a standard long bed, which is about seven feet long. A standard short bed is the more economical option for most people. Compared to a standard long bed, a short bed is easier to drive. However, you might find that you'll spend a lot more time driving your truck.
When towing a pop-up camper, a long bed is not necessary for towing. In addition to the weight of the trailer, you should also setteebet consider the vehicle's weight rating. Towing a trailer with a standard or short bed should be safe for you and the tow vehicle. Remember that a standard bed has a wheelbase greater than the maximum capacity of your vehicle, but a short bed is not as large as a standard truck.
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Today in Impeachment Questions: What the Heck Does "Strike the Last Word" Mean?
The House Judiciary Committee is currently debating amendments to the official articles of impeachment announced earlier this week. They started the "markup" at 7:00 pm Wednesday night and they're expected to approve the articles later today. In the meantime, the "debate" going on is totally exhausting.
As usual, it's less a debate and more lawmakers taking turns repeating their preformed, unwavering talking points. The Democrats all maintain that Trump abused his office and accuse the Republicans of choosing party over country. The Republicans all say the Democrats are acting in bad faith and reading things into Trump's conversation with the Ukrainian president that weren't there. They say the Democrats are being unfair to Trump just because they don't like him. And it's gone on like that, back and forth for five minutes apiece since 7:00 yesterday.
If you're watching or listening to the debate, there is one phrase that's probably sticking out at you: "I move to strike the last word." A lot of representatives have said this today. As NBC Washington's Noreen O'Donnell wrote, "If 'strike the last word' was an impeachment drinking game, no one would survive."
Unless you're a longtime fan of watching Congressional hearings, this might be a new phrase, although by this point, you're probably hoping to never hear it again. Basically, it's just a way for lawmakers to keep the debate going longer.
For each amendment, the reps only have ten minutes of debate time allotted–five in favor and five against. By saying they want to strike a single word from the text, a lawmaker is allowed to keep the debate going. Technically, they should be speaking about that word, but it's understood that they'll be speaking about larger substantive issues.
And what are those substantive issues?
Rep. Jim Jordan wanted to cut the entire first article of impeachment–the whole charge of abuse of power in pressuring Ukraine to investigate Hunter Biden. (You can read the full articles here.) That was shot down after three hours of striking the last word.
THREE HOURS into this House Judiciary Committee hearing, we have the FIRST vote — on Jim Jordan's amendment to strike the first article, abuse of power.
It failed along party lines, as expected.
— Kathryn Watson (@kathrynw5) December 12, 2019
Republican Rep. Matt Gaetz introduced an amendment to cut the reference to Joe Biden from the impeachment articles and replace it with Burisma and Hunter Biden. (That was also voted down along party lines.)
.@RepMattGaetz offers an amendment to add language re: Hunter Biden into the impeachment articles, and mentions his drug problems.
.@RepHankJohnson, D-GA, suggests the "pot calling the kettle black is not something we should do," an allusion to Gaetz's 2008 DUI arrest.
— Ben Siegel (@benyc) December 12, 2019
House Judiciary Chair Jerry Nadler introduced an amendment to change references to "Donald J. Trump" to "Donald John Trump" in the articles of impeachment. That seems like a minor issue, though ranking Republican Doug Collins thinks it illustrates the "absurdity" of impeachment.
The committee is currently on a break but we'll update here with any important news.
Update 5:45pm: A third amendment was voted down along party lines. Republican Rep. Andy Biggs proposed an amendment that would add to the articles the fact that US aid was released to Ukraine. Republicans keep pushing this point because they believe it proves that there was no "quid pro quo" demanded by Trump in regard to asking Ukraine to investigate Hunter and Joe Biden.
(image: Drew Angerer/Getty Images)
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. Reference > Erinsborough News > Valentine's Day Massacre
A romantic weekend turns sour - thanks to Ned...
Love is in the air in Erinsborough this week - unfortunately, Cupid's arrow appears to have fired in all the wrong directions, leaving two couples confused and heartbroken. When Carmella Cammeniti and Dylan Timmins are found in bed together, their respective partners, Oliver and Elle, can only assume the worst. All is not as it seems, however - due to the meddling efforts of nasty Ned...
"To celebrate Valentine's Day, Rosie has organised a weekend getaway," explains David Hoflin, who plays Oliver. "It's meant to be a romantic getaway for Rosie and Frazer, Carmella and Oliver, Dylan and Elle, and Sky and Stingray. But at the last minute, Ned decides that he'll tag along. Nobody realises that he's on a secret mission - to do the dirty work for Elle's father, Paul." Since discovering that Oliver may have inherited a family fortune, Paul's been hell-bent on getting him to partner up with Elle. But before that can happen, he needs to break up existing relationships.
"At this stage, Elle and Dylan are going strong," shares David. "What Carmella and Oliver have together isn't defined, but they're kind of dating. So Ned deliberately ensures Dylan and Carmella get drunk one night, and then puts them in the same bed. The next morning, it appears as to everyone that they've slept together.
"Elle's absolutely furious, and splits up with Dylan immediately," continues the actor. "Oliver finds it more difficult to have a go at Carmella, since they haven't technically made a commitment to each other yet. Nevertheless, it does make him think twice about their relationship." While Paul's plan hits a snag when Oliver finally agrees to give Carmella another chance, the Lassiter's boss' evil scheming is far from over! "Paul stirs everything up with Elle, so eventually she decides that she wants Oliver," David reveals. "The way things are going at the moment, it seems that Oliver and Carmella don't have a hope in hell of staying together..."
This article originally appeared in Inside Soap magazine dated 27th April 2007
Article submitted by Callum
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Religion: Communist
Name: The Soviet Army
Other Names: Sovetskaya Armiya; Russian Army
Classification: supporting characters villains group real/historical group
Earliest Appearance Listed in This Database: The X-Men (vol. 1) #38 (Nov. 1967): "The Sinister Shadow of... Doomsday!"
Creators: Roy Thomas, Don Heck, George Roussos (as George Bell)
Number of Appearances: 8
Enemy of: It, the Living Colossus, unnamed flying mutant, Watchlord, Watchlord's henchmen
Type of Organization/Group: military unit
Suggested links for further research about this character and the character's religious affiliation:
- http://en.wikipedia.org/wiki/Soviet_Army
- http://www.comicvine.com/russian-army/4060-60464/
- http://marvel.wikia.com/X-Men_Vol_1_38
- http://www.uncannyxmen.net/db/issues/showquestion.asp?fldAuto=3038


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February 22, 2023
Introduction of AstraZeneca's Saphnelo (anifrolumab) has Expanded the Use of Biologic Agents in the Treatment of Systemic Lupus Erythematosus (SLE), Resulting in Gains for GSK's Benlysta (belimumab) as Well, According to Spherix Global Insights
Latest Saphnelo launch tracking data from Spherix showcases rheumatologists' shifting perception on the drug's steroid-sparing capabilities yet highlights access barriers hindering use.
EXTON, Pa., February 22, 2023 – Rheumatologists have long struggled to effectively treat patients with systemic lupus erythematosus (SLE) given the wide heterogeneity of the disease and few effective treatment options.
However, after nearly a decade of stagnant innovation for the treatment of SLE and lupus nephritis (LN), physicians now have three (3) approved agents:
- GlaxoSmithKline's Benlysta (belimumab) in SLE and now LN
- Aurinia's Lupkynis (voclosporin) in LN
- AstraZeneca's Saphnelo (anifrolumab) in SLE
At 18 months post approval, monthly tracking by Spherix in the Launch Dynamix series reveals that rheumatologists' familiarity with Saphnelo in SLE continues to grow. While share for Saphnelo among patients with moderate-to-severe SLE remains modest, the introduction of a new agent seems to have propelled the overall use of biologics. Between October 2021 and January 2023, biologic share – consisting of Benlysta, Saphnelo, and off-label rituximab – moved from 16% to 26% according to self-reported use by rheumatologists. Future projections suggest that in the next six months, Saphnelo has the potential to more than double share while Benlysta will continue to trend up modestly as well.
Promotional messaging for both Benylsta and Saphnelo centers around steroid reduction. It is notable that physicians estimate that over half of patients on steroids at Saphnelo initiation have been able to lower their daily steroid dose since starting the drug – a substantial increase from the prior wave of research, accompanied by improved perceptions on the metric relative to Benylsta.
Interviewed rheumatologists expanded:
- "I always tell my students, 'We have to do whatever it takes to get the patients off steroids.' I see a better steroid-sparing with the use of Saphnelo than I do with Benlysta."
- "The purpose of prescribing Saphnelo is to wean down steroids."
- "In general, I do see better steroid-sparing with the use of Saphnelo than with Benlysta and a much faster reduction of steroids. I can get people off steroids within two months. With Benlysta, it's going to take me a lot longer – sometimes three to six months."
While Saphnelo may be pulling ahead of Benlysta somewhat on its perceived steroid-sparing ability, according to the most recent launch tracking data, the drug's biggest advantage over Benlysta is its perceived quick onset of effect, while Benlysta continues to own "safety" and is very much the go-to biologic for SLE, commanding a much larger userbase and patient share in SLE, not to mention an LN indication and a subcutaneous dosing option in addition to IV.
Rheumatologists noted:
- "We are trying to select more patients to go on Saphnelo instead of Benlysta especially if they have arthritis or skin disease…of course, if they have nephritis then I will prescribe Benlysta."
- "I think the onset of action is what is appealing to us. I think the downside is that it's not available subcutaneously."
Rheumatologists' most cited barriers to Saphnelo use include reimbursement hassles, insurance denials, and out-of-pocket costs –highlighting the impact of access issues on uptake. In fact, physician's estimate that one-in-five moderate-to-severe SLE patients are deemed clinically appropriate but not treated with Saphnelo due to insurance coverage and co-pay issues:
Given the high unmet need for new pharmacological options in SLE noted by physicians, there is ample opportunity for agents in the very robust SLE pipeline including Gazyva (obinutuzumab, Roche), dapirolizumab pegol (UCB and Biogen), deucravacitinib (Bristol Myers Squibb), brepocitinib (Pfizer), and Litifilimab (BIIB059, Biogen).
Launch Dynamix™ is an independent service providing monthly benchmarking of newly launched products for the first eighteen months of commercial availability, augmented by a quarterly deep dive into promotional activity, barriers to uptake, and patient types gravitating to the launch brand.
For more information on Spherix's Lupus reports: https://www.spherixglobalinsights.com/rheumatology/lupus/
About Spherix Global Insights
Spherix Global Insights is a leading provider of market research, business intelligence and advisory services to the global life sciences industry. The company's unique service offerings are powered by deep therapeutic knowledge, the Spherix Network specialty physician panel, and commercially relevant analyses to enable strategic decision-making by our valued customers.
A trusted advisor and industry thought leader, Spherix Global Insights provides specialized market expertise in six (6) focused therapeutic areas including: dermatology, gastroenterology, nephrology, neurology, rheumatology and ophthalmology.
To learn more about Spherix Global Insights, visit spherixglobalinsights.com or connect through LinkedIn and Twitter.
Spherix Global Insights Contacts:
Ryan Rex, Rheumatology Insights Director
[email protected]
Scott Upham, Corporate Communications
NOTICE: All company, brand or product names in this press release are trademarks of their respective holders. The findings and opinions expressed within are based on Spherix Global Insight's analysis and do not imply a relationship with or endorsement by any company, brand, or product aforementioned.


text: 2008/12/28 Dylon Edwards <integr8e at gmail.com> > Thanks Riccardo; I recently tried Sage, but it errored out with a message > that some research showed is a bug that was supposed to have been fixed with > the latest release :P I haven't gotten around to trying an older release, > yet, because compiling Sage takes forever and a half... > > Aleix, I'm looking into KOffice's Flake shape library now, what exactly are > you looking for in a Maxima Flake? Can it not already render MathML > objects? It would be the way to make KWord a texmacs-line application in terms of integration with maxima. http://www.texmacs.org/ > > > I want to create a WYSIWYG editor that will simplify the creation of > mathematical documents and solve/plot mathematical expressions; if you > haven't had a professor assign you homework to be completed in Maple or > Mathematica, when you don't have such software at home, you're very > fortunate (it really pretty much sucks). My objective is to create a > mathematical learning environment ( MLE :) useful to both the mathematical > genius and your everyday algebraic n00b; something that will solve > expressions as simple as 1+2*3, while being capable of running CPU intensive > Physics simulations (Step ???), balancing Chemistry equations, solving > vector matrices, and integrating multi-variable expressions. It will > provide the solution to almost any expression entered, and should the user > desire, explain how it was derived (my teachers all through grade school > frowned upon the use of calculators because they can't explain their > solutions). It will be plugin-oriented, with the ability to completely > change its look and feel through various addons and would be able to save > each user-defined "profile" individually. Thus, it would have a very > flexible GUI able of being everything from a calculator, to a WYSIWYG > document editor, to a scripting IDE, all within the same application, and > each with the same capabilities as the other (only friendlier toward their > intended purposes). Such an application will definitely take some time to > develop, and to reduce the maintenance nightmare, will require the > implementation of many already existing open-source projects, but I'm > willing to work toward such a goal. I think you should be able to explain your project with few words. :P > > I've decided to work with Maxima, because in its current state, KAlgebra > cannot handle my math requirements. Next semester I will be taking Calc > III, which introduces all sorts of mult-variable integration funness, and > will shortly be taking Diff Eq's and Linear and/or Abstract Algebra, which > introduce all sorts of other kool' things. However, KAlgebra may very well > be able to deal with those one day, which is why I want to implement a > mathematical API capable of handling multiple backends (so if one can't > handle something, it will be passed to the next). > I don't think you want to mix different backends at the same time. Take in account that you will define variables and expressions on the backend, you could have a bad time at abstracting that and it is not really useful. You can hint the user though. > Sage sounds close to what I'm wanting to create, only it requires the use > of a web browser and expects you to already know what you're doing. What I > want to do is create an application that will not in any way inhibit you if > you happen to know what you're doing, but will be easy for anyone to pick > up, something "n00b friendly, but 1337 oriented." > > > -- > Dylon Edwards > SSWJ - Stay(ing) Strong With Jesus, Always > > _______________________________________________ > kde-edu mailing list > kde-edu at mail.kde.org > https://mail.kde.org/mailman/listinfo/kde-edu > > -------------- next part -------------- An HTML attachment was scrubbed... URL: http://mail.kde.org/pipermail/kde-edu/attachments/20081228/ef1d13b8/attachment.htm


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The last thing you ever want to hear is the sound of trickling water when you own a home. Water damage is one of the most common issues that homeowners face, causing significant harm to personal possessions, building materials, and flooring. When you have invested so much money into a property, you want to protect that investment from water damage. It can be devastating to find out that an incident has left water in your home in places where it shouldn't be.
One room, in particular, has many potential locations where water can leak; the kitchen. With so many appliances and water fixtures in one place, your kitchen could develop a leak for any number of reasons.
Causes of Kitchen Floods
Performing regular maintenance throughout the home is an important part of ownership, but it is especially critical for the kitchen. In this room, you have multiple potential sources of water damage.
Kitchen Sink
If you have a clogged kitchen sink drain, bad water line, or faulty faucet, then your sink could cause a problem in your home. Any of these circumstances could lead to a kitchen flood that will require a lengthy restoration process.
Dishwashers use a lot of water to clean your dishes, which makes them vulnerable to causing a flood in the kitchen. The dishwasher pump could break or drainage could back up and spill water into the rest of the room. A broken pipe that supplies water to the dishwasher could also cause a kitchen flood.
A leaking refrigerator is another common cause of water damage in the kitchen. It could be the result of a failed cooling mechanism, a broken ice maker, or the power could go out and cause melting in the freezer.
Burst Water Lines
Since multiple kitchen appliances use water, they need to draw from the main supply to function. This means the potential for a burst water line is always present in this room.
Water Damage Restoration Process
Cleaning up your kitchen after flooding occurs is a complex process. To prevent further damage from happening to your possessions and the property itself, you will need to respond quickly to mitigate the issue.
Find the Source
First, you need to locate the source of the flooding and figure out how to stop the leak. You may have to turn off the water supply line to the appliance, or even use the main shutoff valve if you cannot find the specific source.
Consider Safety
Depending on the extent of the damage, there could be the risk of electrical hazards or bacterial infections. Before you start cleaning things up and drying out the materials, make sure that you head to the main circuit breaker and shut off nearby power sources. This will prevent unexpected shocks, and potentially, an electrical fire.
Also, wear protective gear such as gloves, boots, and goggles to protect yourself from contaminated water.
Remove Standing Water
Pulling the water that has collected out of the room is the key to a thorough drying process. You can remove standing water from your flooded kitchen with a shop vacuum, wet-dry vacuum, or some sort of pumping equipment. The faster you do this, the better chance you have of saving the kitchen floor and other affected items.
Encourage Air Circulation and Evaporation
With all of the excess water gone, it is time to dry out the affected materials. First, remove as many wet items from the room as you can. See if you can bring them outside to air dry. Then, plug in some heavy-duty fans or air movers to improve circulation in the room. Opening windows, if it is not too humid outside, can also help. The best way to completely dry wet materials is to create constant airflow. Dehumidifiers can then pull the water vapor out of the air.
Cleaning and Disinfecting
Depending on what source caused the kitchen flooding, you may need to clean and disinfect surfaces like cabinet doors, kitchen floors, wood furniture, or walls. The flooded area could be infested with grey water, which is mildly toxic, and would require cleaning solutions using soap or bleach to disinfect the materials with a thorough scrubbing.
Just be sure not to use too much detergent or bleach in your solution. Do not skip this step or your kitchen may never return to its pre-loss condition.
Contact Professional Services if the Job is Too Big
If your flooded kitchen has resulted in a lot of damage to your appliances, kitchen table, building materials, or other items, then you may not be able to handle the problem on your own. In this case, it is best to contact a Portland water damage restoration company. Why should this be your first step?
High-Tech Equipment
You may not have access to the resources that a water damage restoration company can bring to bear to handle your kitchen flood cleanup. They can use high-powered fans, a water meter, a drain hose, and other pieces of equipment to restore a flooded kitchen.
Covered by Your Insurance Company
In most cases, water damage from your kitchen is covered by your insurance company. The exception would be if the water damage was caused by negligence or a natural flood. But if the incident was beyond the homeowner's control, the repair costs will likely be covered.
Since this is the case, it makes logical sense to let professionals handle the flood damage restoration for you. That way, you can feel assured that the job will be done well.
Prevent Further Damage
Addressing the problem quickly is the best way to prevent long-term damage. For water damage restoration, professionals can respond quickly and effectively to the flood in the kitchen. Their experience could save your electrical appliances, kitchen cabinets, and porous materials, and prevent mold growth from occurring. Plus, they can ensure that other rooms are not in danger.
Save Your Kitchen with a Fast Response
Whether you plan to tackle the restoration yourself or will look for professional kitchen remodeling services to help, act quickly to save the kitchen affected by flooding. When you are dealing with a broken water line, leaking appliance, or overflowing kitchen sink, respond immediately to restore your flooded kitchen.


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There will be a virtual informational public hearing on Saturday, July 25, 2020 at 10:00 a.m. to hear from residents about the proposal by the 2020 Trumbull Redistricting Committee to change from four to seven voting districts. The proposal will be on the agenda for approval at the Town Council's next meeting on August 3, 2020. By holding a public hearing prior to the August 3 meeting, the Council will have time to consider public input before voting on the proposal. A second public hearing will be held at the August 3 meeting, which will begin at 7:30 p.m. Information on how to attend that meeting and speak about the issue will be contained in the Council's meeting agenda to be posted on the town website.
When the Town Council formed the 2020 Redistricting Committee in February, it charged the committee with recommending to the Council a redistricting plan comprising voting districts of substantially equal population, including the specific boundary lines of each of those districts. The 2020 Trumbull Redistricting Committee has been meeting since February to come up with a plan, and it has recommended a plan with seven voting districts. The plan can be found on the town website at the following link: https://www.trumbull-ct.gov/728/2020-Trumbull-Redistricting-Committee.
To attend the public hearing, please join the meeting online by going to: https://zoom.us/j/98850808037?pwd=aUl0clBIejdQb1JSa0JNbC9MQ0tpZz09 and using Webinar ID: 988 5080 8037 and Password: 677533. Or join by telephone by dialing: (312) 626-6799 or (888) 475-4499 (Toll Free) and using Webinar ID: 988 5080 8037.


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Should Your Crypto Startup Accept Venture Capital
Should your crypto startup accept venture capital funding? It's a simple question, but one laced with a web of considerations. The best ideas can't be realized on a shoestring: the money to form a team, develop a proof of concept, and bring a consumer-ready product to market has to come from somewhere.
If not from VCs, where? Most founders don't have pockets deep enough to self-fund, while public token sales are dependent on two things: a token and a product the mass market can get behind. That instantly rules out a significant proportion of all projects including B2B, most middleware, and those that lack an onchain component altogether such as crypto marketing or apparel.
Deciding whether to take the VC pill or shun it altogether is one of the toughest decisions a startup will face. Whatever their choice, it's one that will have lasting ramifications.
To VC or Not to VC?
While 2022 will go down as a bad year for crypto, with every meaningful industry benchmark a fraction of its 2021 high, venture capital still flowed. The Block reports $31 billion of industry investment last year, $8B of which went into NFTs and GameFi. The report also claims that 78% of all blockchain venture funding occurred within the last two years. It's clear that for a significant proportion of crypto projects, accepting venture funding was never in question. Not all web3 startups have followed that well-trodden route however.
Peer is a blockchain and metaverse company working at the convergence of mixed reality and spatial computing. It proposes using AR to embed digital objects into physical spaces, allowing NFTs to be "buried" anywhere in the real world. It's not just Peer's tech that's novel, however: so's its funding route.
Founder Tony Tran was able to cover the initial costs himself before raising $14M via a private sale of Peer's L1 coin, PMC, to friends and family. This was done via a Reg D offering to meet the SEC's filing requirements. While this approach has proven successful for Peer, which is following its private round with a public token sale, not all founders have the fortune of an inner circle of HNW individuals.
Given the choice between accepting VC funding and abandoning the project, picking the former is a no-brainer. The trick is in determining how much of your company to give away – and to whom.
Know Your Venture Capitalists
VCs are meant to be in it for the long haul. When they're accepting equity, they have little choice but to support the companies they've funded until the time comes to exit, which could arrive years down the line – if ever. When accepting tokens, however, as is often the case with crypto startups, VCs are only bound by the lock-up period. When venture capital firms are aligned with the startup's goals, they have little interest in market dumping their allocation at the earliest opportunity. But when the entire market heads south, as was the case last year, less scrupulous VCs are prone to selling everything they can get their hands on.
Dumping on retail isn't the only crime VCs stand accused of; they can also impair a project by being too overbearing. There's a fine line between incubating a startup and throttling it. When a lead investor shares your vision, and works with you to realize it, it can feel more like a partnership; conversely, when VCs attempt to micro-manage or steer the ship, it can suck the life out of a project.
So what's the solution? If you can't bring your product to market without millions of dollars, venture capital is almost inevitable. That's assuming your concept is good enough to whet their appetite of course; during bear markets, VCs become understandably picky about the checks they write.
While not every startup can attract a16z, they can weed out the firms that are only in it for a quick flip. Study the landscape, talk to other teams who obtained private funding, and learn from their experience, be it good or bad. VCs often get a bet rep, with Cobie claiming that they "basically do nothing post-cash. They give no feedback, don't participate in governance, don't even talk to the project founders after the round is closed."
The reality is more nuanced. Just as VCs are compelled to invest wisely, startups should accept investment wisely. VCs can be the lifeblood of a new venture. Pick the right venture capitalists and everything that follows next should fall into place.


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