text:
NEW YORK ( TheStreet) -- Adjustable-rate mortgages have been in the doghouse for years, shunned by borrowers who heard horror stories about homeowners whose ARM rates soared in the '00s, driving monthly mortgage payments through the roof. On Wednesday the Mortgage Bankers Association reported that only 4% of mortgage applicants were seeking ARMs. But maybe it's time to reconsider. For some borrowers, an ARM can be cheaper than a fixed-rate mortgage. Also, ARM rates are enticingly low right now but could rise as the economy improves. Annual and lifetime caps based on today's low starting rates would prevent a borrower's future ARM rates from going too high. As the name implies, an adjustable-rate mortgage has a floating interest rate. Typically, it starts out low -- lower than you'd pay on a fixed-rate loan that charges the same rate for its lifetime. After an initial period of one to 10 years, the ARM rate adjusts every 12 months. The new rate is figured by adding a "margin," such as 2.75 percentage points, to an index such as the rate paid by a specific bond. The borrower saves money by paying a lower rate in the initial period than on a fixed-rate loan. But there is a risk the ARM rate will someday go higher than the borrower would have paid with a fixed-rate deal. In the past few years, rates on 15- and 30-year fixed-rate loans have been so low that most borrowers figured it was better to lock in a fixed rate than take chances on an adjustable one. So why look at ARMs now? Mainly because ARM rates are likely to rise, so that today's ARM is probably a better deal than the one you might get in a year or two. ARMs come with caps that typically prevent future adjustments from rising more than 2 percentage points a year, or 5 or 6 points over the loan's life. If you start at an exceptionally low rate today, like the 2.7% average for five-year ARMs, you'll never pay more than 8.7%, which is not especially high by historical standards.
Of course, a rise that high would cause a dramatic increase in your monthly payment, so it would make no sense to get this ARM if you really thought rates would go that high and stay there. You'd be much better off getting today's 30-year, fixed-rate loan, averaging 3.5%. This means the best candidate for an ARM is the borrower who expects to pay off the loan during the initial period, such as five, seven or 10 years, while the rate is fixed. This would include one who is buying a home that is likely to be sold during that period. It would also include a homebuyer, or a homeowner who is refinancing an older mortgage with a high rate, who is capable of making extra payments to retire the loan ahead of schedule. A homeowner who is refinancing, for instance, may have already reduced the original loan balance substantially. With a lower interest rate on the ARM and a modest loan balance, it might be possible to pay off the new ARM during the initial period with a monthly payment similar to that of the old loan. In the same way, a buyer with plenty of resources could make extra principal payments to pay the loan off while the rate remains low. Even if these borrowers failed to retire the debt during that initial period, reducing the debt through extra payments would reduce the pain if the rate did rise in the future. Check your numbers with this calculator. The key, then, to making an ARM work: Be sure you can afford the payment at the maximum rate the ARM could charge, or make extra payments so you never face a burdensome payment.


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We are working on the next Sabayon 4.1 release and things are going well.
As you might know, this time we want to do things slightly different. Ironicly we always do things different. But this time we decided to work on 2 different DVD's based on the previous succesfull release of liteMCE.
The G disc:
This will be allot like the liteMCE disc which features gnome as its desktopmanger.
The G disc doesn't need much work. Since its mostly an updated packages/artwork version of liteMCE.
The K disc:
This would be the same thing as the G disc but with KDE 4.2.1 as its desktopmanager.
Now this one will take more time because we want to tackle some practical problems. We want to ship the K with the most pure KDE/Qt programs and we need to work out some of the artwork issues like GTK applications (e.g. firefox) that are looking ugly.
So i went looking and found a nice replacement for Gparted:
This package is already available in entropy. Please note that its still marked as beta and on my system it took a while before it loaded up on my screen.
Another thing we wanted to add to the K disc is a nice little program that lets you edit the grub menu and even reinstall grub in case of an emergency.
The GRUB editor program is now in entropy.
Any further suggestions are welcome.

subset: commoncrawl


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Windows Memory Analysis
Analysis of physical memory from Windows systems can yield significant information about the target operating system. This field is still very new, but holds great promise.
Sample Memory Images
Getting started with memory analysis can be difficult without some known images to practice with.
- The 2005 Digital Forensic Research Workshop Memory Analysis Challenge published two Windows 2000 Service Pack 1 memory images with some malware installed.
- The Digital Forensics Tool Testing project has published a few Windows memory images.
See Also
During the 1990s, it became a best practice to capture a memory image during incident response. At the time, the only way to analyze such memory images was using strings. Although this method could reveal interesting details about the memory image, there was no way to associate what data came from what program, let alone what user.
In the summer 2005 the Digital Forensic Research Workshop published a Memory Analysis Challenge. They distributed two memory images and asked researchers to answer a number of questions about a security incident. The challenge produced two seminal works. The first, by Chris Betz, introduced a tool called memparser. The second, by George Garner and Robert-Jan Mora produced kntlist.
At the Blackhat Federal conference in March 2007, AAron Walters and Nick Petroni released a suite called volatools. Although it only worked on Windows XP Service Pack 2 images, it was able to produce a number of useful data.
External Links
- Jesse Kornblum Memory Analysis discussion on Cyberspeak
- http://cyberspeak.libsyn.com/index.php?post_id=98104


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This morning, Gizmodo HQ ended up in a conversation over the utility of pennies. We all agree that they're pretty useless. For the most part, they just end up in pockets and drawers and jars. It costs more than a penny to produce a penny. And trying to pay for something in pennies will net you a ticket. Ugh.
Our editorial assitant Mario took a year's worth of saved up pennies to a Coinstar machine and know how much he got back? Five bucks. Ugh ugh. Pennies should just go away, right? I mean, what benefit, if any, do they provide to you?
Photo credit: (C) Franklin Jr. / Stockfresh.


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Touch Downy Super Bowl Twitter Party (with Giveaways!)
Saturday, February 4, 2012
Tomorrow (Super Bowl Sunday), Downy will be giving away prizes fore very touchdown scored during the game! Prizes include sample of Downy Unstopables and Unstopable Fan Packages!
Follow Downy on Twitter to participate in the party using the hashtag #TouchDowny. Each time a team during the Super Bowl tomorrow scores a touchdown, tweet at Downy and be entered to win! (Tip: Use Tweetgrid or Tweetchat to view all tweets for this hashtag!)
Winners will be notified via DM on Twitter - so be sure you're following them!
Check out this Super Bowl ad, featuring Mean Joe Greene and Amy Sedaris!
Disclaimer: I was not sent any product or monetary items to participate in this One2One Network campaign, but I do have the opportunity to win a gift card just by posting this article. On the other hand, I LOVE Downy Unstopables - this product smells great!
My opinions are my own and yours may differ - as we are all human and not created 100% the same. ;-)


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I recently laid out the fundamental problem with the US economy:
Massive consumer debts and high unemployment are crippling consumer spending, which accounts for about 70% of our economy.
I noted that, to get the economy healthy again, consumers have to get back to work and reduce their debts. This latter process has begun, but it will take significantly more time, probably another decade.
No one can wave a magic wand and make consumer debt go away. (If they could have, they would have).
What someone can do is wave a magic wand and create jobs--jobs that benefit the whole country and put spending money back in consumer's pockets.
Who can wave that magic wand?
The government.
Instead of cutting spending and firing people, the way it has been for the last few years, the government can do the opposite: Commit to spending, say, an extra $2-$3 trillion over the next decade to rebuild our country's infrastructure--and create work and awesome infrastructure for millions of Americans in the process.
Yes, the government could also commit to hiring more teachers, firefighters, policemen, and other folks who generally improve life for all Americans. But hiring those folks is much more controversial. So the government should start with a massive infrastructure spending program.
But wait. Can we afford to spend $2-$3 trillion on infrastructure? We already have $15 trillion of debt, and we're accumulating more debt at a rate of more than $1 trillion per year!
The answer is.... yes, we can afford it. As long as we commit to fixing our social-insurance programs (Social Security, Medicare, Medicaid) over the next decade. Those programs are what are slowly bankrupting this country, not infrastructure spending. And in the meantime, our infrastructure is collapsing.
Don't think we should initiate a massive infrastructure spending program? Believe folks who tell you that "government spending doesn't work?" Think the 2009 stimulus proves that government spending doesn't work?
Then read on...
The economy is basically composed of three big spending engines —consumers, corporations (investment), and governments. So when the first two weaken, as they have in recent years, the third can help offset this weakness.
Specifically, the government can increase its spending to offset the lost consumer and business spending.
When governments spend money well, moreover—such as on infrastructure projects that benefit all citizens—the impact of this spending lasts far beyond the years in which the money is spent. Roads, bridges, schools, airports, national broadband networks, and other investments can improve the country for decades. When the government spends money badly, meanwhile--on bailouts and handouts and by perpetuating unsustainable promises of entitlement programs--the money is just wasted.
Ever since the 2009 stimulus "failed to fix the economy," the consensus in the US has been that government stimulus doesn't work. There's actually a lot of evidence to suggest that it did work, or at least helped improve the situation ( check out these charts). But the theory that government spending "doesn't work" is pervasive.
In support of this theory, everyone first points to Japan, where the government has been frantically "stimulating" the economy for two decades now. Then they point to the Great Depression, with its massive public-works programs.
But other evidence suggests that the impact of government stimulus, specifically infrastructure stimulus, is being badly misunderstood.
The work of economist Richard Koo, for example, suggests that Japan's stimulus has been vastly more successful than is commonly believed.
Far from not working, Koo argues, Japan's government stimulus has kept Japan's economy alive for the past 20 years. Without the stimulus, Koo says, Japan's economy would not have crawled along for the last two decades—it would have collapsed.
When the same logic is applied to the US stimulus of 2009-2010, the conclusion is that the stimulus "failed to fix" the US economy, but that it kept the recession from being much worse.
In addition to Japan, one of the most often-repeated examples cited by those who say stimulus doesn't work is the US experience in the Great Depression. To see that stimulus doesn't work, they say, all you need to do is look at the huge public-works programs of the 1930s, which failed to pull the US permanently out of the Depression. What finally got the US out of the Depression, these folks continue, was World War 2.
But what was World War 2 if not a gigantic government stimulus?
That's exactly what World War 2 was. It put the US government deeply in debt, vastly deeper in debt than we are today. But it got our production engine humming again. And it set the stage for decades of impressive growth, during which we eventually worked off the World War 2 debt.
So there's a lot of evidence to suggest that the current consensus that stimulus "doesn't work" is flat-out wrong.
In fact, the evidence suggests, stimulus can keep the economy from collapsing while the private sector heals itself.
And this, in turn, suggests that ruling out future stimulus in the form of infrastructure investment as a way to help the economy is a major mistake, especially with US infrastructure in such lousy shape and so many US workers idled by the construction industry slowdown.
To learn more about how government stimulus helps economies get through depressions, flip through some of Richard Koo's excellent slides below. They focus on Japan, the Depression, and recent US and Europe experiences...


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HOUSTON – Though it's not a full-fledged stadium, the Houston Dynamo's brand-new practice facility has the club feeling like it's finally establishing roots in Houston.
The Dynamo on Wednesday celebrated the grand opening of the Methodist Champions Field at the Houston Amateur Sports Park, which will serve as the team's training facility.
Much attention recently has been paid to the development of the Dynamo's soccer-specific stadium, but opening their own practice facility is a welcome step by the players and coaches.
"It's been a long time coming for me and guys like Brian [Ching] and Brad [Davis] and the guys who have been in the league a while but have never had their own place to train," veteran defender Eddie Robinson said.
[inline_node:333732]Since coming to Houston, the Dynamo have trained at the Carl Lewis Track and Field complex at the University of Houston, often sharing the facility and their time on the pitch with the school's athletes. It's customary when at training to have to watch for sprinters or for the team to put up signs to make sure people didn't cross the field during training.
The new facility – which will initially include six fields available for public use – will be under the control of the Dynamo organization, which means the club will have a say over the conditions of their training pitch. That's something they did not have at the University of Houston.
Another positive is that the Dynamo will have the ability to train on both a turf and natural-grass field, making preparations for trips to stadiums with field turf easier.
"I think it's been great since we've been here, but there are a few facilities that we need," said head coach Dominic Kinnear. "One is a stadium and the other's a training facility like this. The field is flat; it rolls well. It's a little soft but we do a good job of maintaining where we play to make sure the field stays in good shape."
With the stadium slated to open in early 2012, the team is feeling an increased presence as part of the professional sports landscape in Houston.
"Having a place to call your own is nice and adds to the professional feel for the club," said Ching. "Along with that, I think it could help to bring in DP-type players. We haven't had that in the past and now with the fantastic place to train, it will help us attract some big-name players."
Darrell Lovell covers the Houston Dynamo for MLSsoccer.com. Follow him on twitter at @Dynamoexaminer.


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IAU XXVIII General Assembly: Special Session #13
High-Precision Tests of Stellar Physics from High-Precision Photometry
The COROT and Kepler space missions were designed and built to use high-precision photometry to find planets - particularly small ones - around other stars by detecting transits. These missions follow on the path led by surveys and missions such as MOST, MACHO, and OGLE, and are complemented by other photometric surveys for planets (XO, WASP, HATnet, etc.). To do this they stare at large fields for extended periods of time. Also, extremely high photometric precision (about 1:100,000 in the case of Kepler) is needed to find Earth-sized planets.
Such precision is well beyond what has been done before, and having continuous data for a large number of stars is even better. Any study of that kind will unearth types of variations not seen or appreciated before in addition to the trove of planets discovered. Those variations are being studied and are leading to all-new insights into the physics of stars across the H-R diagram.
Supporting Commissions:
- Commission 25 - Stellar Photometry & Polarimetry
- Commission 26 - Double & Multiple Stars
- Commission 27 - Variable Stars
- Commission 37 - Star Clusters & Associations
Important Note
Joint Discussion 13 is part of the scientific programme of the XXVIII General Assembly of the International Astronomical Union, which will take place in Beijing, China, August 27-31 2012. This website contains information directly relevant to the Special Session #13: High-Precision Tests of Stellar Physics from High-Precision Photometry. Please check the GA website for all other information, including accommodations, social program, Visa information, etc.


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The winter snowstorm that tormented the Midwest has become a major, slow-moving nor'easter that has already brought snow, coastal flooding and whipping winds to the Northeast.
Parts of the New Jersey coastline were already underwater Wednesday night, which prompted voluntary evacuations in Toms River and Brick while the Shrewsbury River flooded local streets in Sea Bright, according to ABC News station WABC.
Overnight, the highest wind gust recorded off New Jersey was 71 mph, and 30 to 50 mph winds are expected to last until Friday morning, which could bring 13-foot waves just offshore.
The high winds are expected to bring down power lines as more than 2,000 people are without power in New Jersey as of 4 a.m., WABC reported.
Overnight, snow started to fall in parts of Long Island. New York City is expecting a snowy, rainy mix with a chilly wind today with another round of snow in the forecast tonight.
New York City is expected to get up to 3 inches of snow by the time the storm system moves out Friday morning, with some higher storm total amounts possible on eastern Long Island. Boston may see 2 to 4 inches, with higher totals inland where a winter storm warning has been issued from Worcester to just north of Providence.
Winter warnings are posted in seven Northeast states. The biggest snowfall totals will come Friday, and parts of New England could see more than 6 inches of snow.
Still shaken from superstorm Sandy, those along the shore are scrambling to protect the fragile coastline from the storm surge and beach erosion.
Diane Harkoff owns a restaurant along the shore in Suffolk County, N.Y. She still hasn't gotten over the amount of devastation caused by Sandy last October.
"I want the water to stay in its place. I want a miracle, that's what I want. I don't want to go through this ever, ever again," Harkoff told ABC News Radio.
More than 440 flights have been canceled for today, according to FlightAware.com. New York's LaGuardia Airport has the most cancellations, followed by Newark Liberty International in New Jersey. This storm system has caused headaches for travelers, as more than 4,000 flights have been canceled so far this week.
This winter storm has already socked much of America's heartland. Virginia declared a state of emergency: More than 250,000 people were without power at one point as tree branches gave way under the weight of heavy snow.
Parts of the state saw 20 inches of snow, and the National Guard was brought in to clear roads, where accidents piled up.
In North Carolina Wednesday, firefighters say the roads are dangerous because they had rain before the temperatures began to plunge. That caused a layer of ice to form under the snow.
Bobbi Havron was a passenger in a vehicle involved in bad accident in the town of Boonie.
"I was holding my breath and closed my eyes and just counted the bangs. He hit us about two times in the front. And then he slammed into the side of us and pushed us down the embankment, and I just kept praying that we weren't on the other side of the hill where there is a drop-off," Havron told ABC News Radio.
The current storm led to at least four deaths, the AP reported. A semi-trailer slid off a snow-covered interstate in western Wisconsin, killing two people. A central Indiana woman died when a semi-trailer plowed into her car after she lost control merging onto the highway, and a man from Columbia City in northeast Indiana was killed when his snowmobile left the road, headed across a field and crashed into a wire fence.
ABC News Radio and The Associated Press contributed to this report.


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Protect Yourself Against Online Fraud with Trusteer Rapport Software
Protect Yourself with Trusteer Rapport
Rapport is lightweight security software that helps to protect your online banking communication from being stolen by criminals. Rapport is highly recommended by Lake City Bank as an additional layer of security to any anti-virus or security software you already use. By protecting your internet connection and creating a tunnel for safe communication with Lake City Bank's online website, Rapport helps to blocks malicious attempts to steal money from your account.
What's at Stake
Criminals are after your money and identity. Inevitably, your online bank account has access to both. If criminals manage to access your online bank account, they can not only access your private information but also transfer money out of your account. Lake City Bank has taken various measures to protect you against this threat, but one of the biggest risks is actually the computer you use to bank with.
Here are two sophisticated attacks that criminals use to access your online bank account using your computer:
Malicious software (or malware) – automatically and silently downloaded onto your computer when you browse the Internet, malware silently captures your login information and transfers it to criminals as you log-in to your bank's website. It is also capable of silently changing the transactions you execute as directed by criminals.
Phishing – criminals build fake websites that look very similar to your bank's website. They do this to lure you into visiting these fake websites and submitting your online banking log-in information. This data is later used to access your online bank account.
Why Your Current Computer Security is Not Enough
It takes days or even weeks for anti-virus vendors to identify and remove new variants of financial malware. Until they manage to do so, the malware is still undetected on your computer. Cyber criminals can attack your bank account minutes after you get infected with financial malware and way before this malware is detected and removed by your anti-virus.
Trusteer Rapport – Dedicated Online Banking Security
Trusteer Rapport takes a unique approach that adds real value on top of your current security software. When you connect to Lake City Bank online, Rapport does three main things in the background to make it extremely difficult for criminals to target you:
Rapport verifies that you are really connected to the Lake City Bank's genuine website as opposed to a fake website created by criminals. Although this sounds trivial, it's not obvious that you reach a genuine website when you type your bank's address into your web browser.
Once verification is complete, Rapport locks down communication between your computer and Lake City Bank's website. This prevents criminals from hijacking your online connection with the bank.
Rapport protects your computer and internet connection by creating a tunnel for safe communication with Lake City Bank, preventing criminals from using malware to steal your log-in data and tamper with transactions.
Rapport takes several additional steps in the background to further improve security. If you are interested in reading about them, please click here.
Compatible with Your Current Security Software
Rapport works alongside your current security software to provide comprehensive protection when you bank online. Rapport also communicates with Lake City Bank's security systems. This allows Lake City Bank to better use its security systems to protect your online account and block malicious attempts to steal money from your account.
Available at No Cost to You
Trusteer Rapport is available to Lake City Bank Internet Banking clients at no charge! Lake City Bank covers all costs associated with the development, maintenance and support of Trusteer Rapport.
100 banks and 20 million customers are already using Rapport today to prevent online fraud. Trusteer, the security experts behind Rapport, makes every effort to ensure Rapport remains constantly updated with the ability to protect you against new and emerging security threats.
Easy to Use
Rapport is very easy to download and use. Here's what you need to do:
1. Click the "Download Rapport Now" button to install it on your computer. This only takes a couple of minutes.
2. Click "next," "yes" and "continue" when prompted, until installation is complete. There's no need to restart your computer once the process is complete.
3. Once installed, a small Rapport icon will appear next to your browser's address bar. The Rapport icon is green when you are on a website protected by Rapport, and grey when you are on a website that is not protected by Rapport. The icon is for your information only and does not require any action from your end.
4. When you first log onto your bank account after installing Rapport, you will see a message asking you to approve the protection of your online banking login information. From there on, Rapport works in the background and only pops up if a security risk is identified.
Support When You Need It Most
Trusteer operates a 24 hour customer center to help with any questions or issues you may have. Click here for live chat, telephone and email support.
System Requirements
Click here for updated system requirements.
You can still have Rapport running even if most of your browsing is done using an unsupported browser. Rapport does not interfere with your browsing. You can always choose to switch to a supported browser when you log onto a sensitive website such as your online banking website.


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Gwyneth Paltrow wants to see an end to online bullying, insisting posting hateful comments on the Internet is "dehumanising".
The actress admits she is sometimes affected by barbed remarks hurled at her online, and she told a conference for website coders on Tuesday that nasty comments are still hurtful, even if the victim is a star.
She said, "Celebrities, we've always gotten stones thrown at us and, you know, for good reason: We're annoying. Some of us look okay, we look like we have money, our lives seem great. That may or may not be the case… Nevertheless, we get it. Or, at the very least, we expect that it's part and parcel to (sic) what we do.
"Anyone in any field who has their head rise above a poppy in the field, they get their heads chopped off. It's our human nature to feel that way, and to do it… Everybody takes s**t, it's just the way it is."
However, the Iron Man star, who announced her split from husband Chris Martin in March, insisted cyber-bullying is like "the scabs from your high school wounds being ripped off on a daily basis," adding, "You come across (online comments) about yourself and about your friends, and it's a very dehumanising thing. It's almost like how, in war, you go through this bloody, dehumanising thing, and then something is defined out of it. My hope is, as we get out of it, we'll reach the next level of conscience."
Gwyneth Paltrow wants to see an end to online bullying, insisting posting hateful comments on the Internet is "dehumanising".


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Severent Diskus (Inhalation)
Generic Name: salmeterol (Inhalation route)
sal-ME-ter-ol zye-NAF-oh-ate
Medically reviewed by Drugs.com. Last updated on Jan 30, 2019.
Commonly used brand name(s)
In the U.S.
- Serevent
In Canada
- Serevent Diskhaler Disk
- Serevent Diskus
- Severent
- Severent Diskhaler
- Severent Diskus
Available Dosage Forms:
- Powder
Pharmacologic Class: Salmeterol
Uses for Severent Diskus
Salmeterol is used together with other medicines (such as inhaled corticosteroids) to treat asthma and prevent bronchospasm in patients with asthma. When used regularly every day, inhaled salmeterol decreases the number and severity of asthma attacks. However, it will not relieve an asthma attack that has already started.
Salmeterol is also used to treat air flow blockage and prevent the worsening of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. This medicine is also used to prevent wheezing caused by exercise (exercise-induced bronchospasm or EIB).
Salmeterol is a long-acting bronchodilator. Bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.
This medicine is available only with your doctor's prescription.
Before using Severent Diskus
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of salmeterol in children above 4 years of age. Safety and efficacy have not been established in children younger than 4 years of age.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of salmeterol in the elderly. However, elderly patients with heart problems may require special caution when receiving salmeterol.
|Pregnancy Category
|All Trimesters
|Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Fluconazole
- Posaconazole
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Alfuzosin
- Amiodarone
- Amprenavir
- Apomorphine
- Arsenic Trioxide
- Asenapine
- Astemizole
- Atazanavir
- Azithromycin
- Boceprevir
- Ceritinib
- Chloroquine
- Chlorpromazine
- Ciprofloxacin
- Citalopram
- Clarithromycin
- Clozapine
- Cobicistat
- Conivaptan
- Darunavir
- Dasabuvir
- Disopyramide
- Dofetilide
- Dolasetron
- Domperidone
- Droperidol
- Fingolimod
- Flecainide
- Fosamprenavir
- Fosnetupitant
- Gatifloxacin
- Gemifloxacin
- Granisetron
- Halofantrine
- Haloperidol
- Ibutilide
- Iloperidone
- Indinavir
- Itraconazole
- Ketoconazole
- Lapatinib
- Lopinavir
- Lumefantrine
- Mefloquine
- Mifepristone
- Nefazodone
- Nelfinavir
- Netupitant
- Nilotinib
- Norfloxacin
- Octreotide
- Ofloxacin
- Ombitasvir
- Ondansetron
- Paliperidone
- Paritaprevir
- Procainamide
- Prochlorperazine
- Promethazine
- Propafenone
- Quinidine
- Quinine
- Ranolazine
- Ritonavir
- Saquinavir
- Sodium Phosphate
- Sodium Phosphate, Dibasic
- Sodium Phosphate, Monobasic
- Solifenacin
- Sorafenib
- Sunitinib
- Telaprevir
- Telavancin
- Telithromycin
- Tetrabenazine
- Tipranavir
- Toremifene
- Trazodone
- Trifluoperazine
- Vardenafil
- Voriconazole
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Erythromycin
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Asthma attack, acute or
- Bronchospasm (difficulty with breathing), acute or
- COPD flare-up—Should not be used in patients with these conditions.
- Diabetes or
- Heart or blood vessel disease or
- Heart rhythm problems (e.g., arrhythmia, QT prolongation) or
- Hypertension (high blood pressure) or
- Hyperthyroidism (overactive thyroid) or
- Hypokalemia (low potassium in the blood) or
- Ketoacidosis (high ketones in the blood) or
- Seizures, history of—Use with caution. May make these conditions worse.
Proper use of salmeterol
This section provides information on the proper use of a number of products that contain salmeterol. It may not be specific to Severent Diskus. Please read with care.
Inhaled salmeterol is used to prevent asthma attacks and to treat chronic obstructive pulmonary disease (COPD). It is not used to relieve an asthma attack that has already started. For relief of an asthma attack that has already started, you should use another medicine. If you do not have another medicine to use for an attack or if you have any questions about this, check with your doctor.
This medicine comes with patient directions or a medication guide. Read the directions carefully before using this medicine. If you do not understand the directions or you are not sure how to use the Diskus®, ask your doctor or pharmacist to show you what to do.
Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine without telling your doctor. To do so may increase the chance of having breathing problems.
In order for this medicine to help prevent asthma or COPD attacks, it must be used every day in regularly spaced doses, as ordered by your doctor.
To use the Diskus®:
- Open the foil pouch containing the Diskus®.
- To open the Diskus®, push the thumb grip away from you as far as it will go. You will hear a click and feel a snap. When open, the mouthpiece will appear.
- Slide the mouthpiece lever away from you as far as it will go until it clicks. The Diskus® is now ready to use. If you close the Diskus® or push the lever again, you will lose medicine.
- Turn your head away from the Diskus®, and breathe out to the end of a normal breath. Do not breathe into the Diskus®.
- Holding the Diskus® level, put the mouthpiece between your lips and teeth, and close your lips around the mouthpiece. Do not bite down on the mouthpiece. Do not block the mouthpiece with your teeth or tongue.
- Breathe in through your mouth as deeply as you can until you have taken a full deep breath. Do not breathe through your nose.
- Hold your breath and remove the mouthpiece from your mouth. Continue holding your breath as long as you can up to 10 seconds before breathing out slowly. This gives the medicine time to settle in your airways and lungs.
- Turn your head away from the Diskus®, and breathe out slowly to the end of a normal breath. Do not breathe into the Diskus®.
- If your doctor has told you to inhale more than one puff of medicine at each dose, take the second puff using exactly the same steps you used for the first puff.
- When you are finished, close the Diskus®. Place your thumb on the thumb grip, and slide it back toward you as far as it will go. You will hear it click shut.
- Keep the Diskus® dry. Do not wash the mouthpiece, or any other part of the Diskus®. You may use a dry cloth to wipe it clean.
- The Diskus® has a window that shows the number of doses that are left. This tells you when you are getting low on medicine. When the Diskus® has 5 doses left, the numbers from 5 to 0 will show up in red to remind you to refill your prescription.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For inhalation dosage form (powder):
- For preventing an asthma attack:
- Adults, teenagers, and children 4 years of age and older—One inhalation (50 micrograms [mcg]) two times per day (morning and evening). The doses should be at least 12 hours apart.
- Children younger than 4 years of age—Use and dose must be determined by your doctor.
- For maintenance treatment of COPD:
- Adults—One inhalation (50 micrograms [mcg]) two times per day (morning and evening). The doses should be at least 12 hours apart.
- Children—Use and dose must be determined by your doctor.
- For preventing exercise-induced bronchospasm (EIB):
- Adults, teenagers, and children 4 years of age and older—One inhalation (50 micrograms [mcg]) taken 30 minutes before exercise.
- Children younger than 4 years of age—Use and dose must be determined by your doctor.
- For preventing an asthma attack:
Missed dose
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Throw the medicine away 6 weeks after it is removed from the foil pouch or after all the blisters have been used.
Precautions while using Severent Diskus
If you will be taking this medicine for a long time, it is very important that your doctor check the progress of you or your child at regular visits. This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects.
Tell your doctor if you are also using other medicines for your COPD. Your doctor may want you to stop using the medicine and use it only during a severe COPD attack. Follow your doctor's instructions on how you should take your medicine.
This medicine should not be used if you are having a severe COPD attack, or if symptoms of COPD attack has already started. Your doctor may prescribe another medicine for you to use in case of an acute COPD attack. If the other medicine does not work as well, tell your doctor right away.
This medicine should only be used as an additional treatment for patients who cannot be treated with other asthma medicines (such as inhaled corticosteroids) or for asthma patients that require two medicines, including salmeterol. Ask your doctor if you have any questions.
Although this medicine decreases the number of asthma attacks, it may increase the chance for a severe asthma attack when they do occur. Be sure to read about these risks in the Medication Guide and talk to your doctor or pharmacist about any questions or concerns you may have.
You should not use this medicine if your asthma attack has already started. Your doctor will prescribe another medicine (e.g., a short-acting inhaler) for you to use in case of an acute asthma attack. Make sure you understand how to use the short-acting inhaler. Talk to your doctor if you need instructions.
Do not use any other asthma medicine or medicine for breathing problems without talking to your doctor. This medicine should not be used with other inhalers that contain budesonide and formoterol combination (Symbicort®), fluticasone and salmeterol combination (e.g., Advair® Diskus®, Advair® HFA), formoterol (Foradil® Aerolizer®, Perforomist™), or arformoterol (Brovana™).
Talk to your doctor or get medical care right away if:
- Your or your child's symptoms do not improve after using this medicine for 1 week or if they become worse.
- Your short-acting inhaler does not seem to be working as well as usual and you or your child need to use it more often (e.g., you use 1 whole canister of the short-acting inhaler in 8 weeks time, or you need to use 4 or more inhalations of the short-acting inhaler for 2 or more days in a row).
- You or your child have a big decrease in your peak flow when measured as directed by your doctor.
Do not change your dose or stop using your medicine without first asking your doctor.
Your doctor may want you to carry a medical identification (ID) card stating that you or your child are using this medicine. The card will say that you may need additional medicine during an emergency, a severe asthma attack or other illness, or unusual stress.
This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. Paradoxical bronchospasm may be life-threatening. Stop using this medicine and check with your doctor right away if you or your child are having a cough, difficulty with breathing, shortness of breath, or wheezing after using this medicine.
If you or your child develop a skin rash, hives, or any allergic reaction to this medicine, stop using the medicine and check with your doctor as soon as possible.
Check with your doctor right away if you or your child have chest pain, a fast heartbeat, nervousness, shaking of the hands or feet, noisy breathing, a feeling of choking, or tightness or irritation of the throat while using this medicine.
Hypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you or your child have more than one of the following symptoms: convulsions; decreased urine; dry mouth; increased thirst; irregular heartbeat; loss of appetite; mood changes; muscle pain or cramps; nausea or vomiting; numbness or tingling in the hands, feet, or lips; shortness of breath; or unusual tiredness or weakness.
This medicine may affect blood sugar levels. If you or your child are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Severent Diskus side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
- Cough producing mucus
- difficulty with breathing
- headache
- irritation of the throat
- runny nose
- shortness of breath
- sneezing
- stuffy nose
- tightness in the chest
- wheezing
Less common
- Abdominal or stomach pain
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- chills
- colds
- cough or hoarseness
- diarrhea
- difficulty breathing
- dizziness
- dry mouth
- fever
- flu-like symptoms
- flushed, dry skin
- fruit-like breath odor
- general feeling of discomfort or illness
- increased hunger
- increased thirst
- increased urination
- joint pain
- loss of appetite
- muscle aches and pains
- nausea
- nervousness
- noisy breathing
- pain
- pain or tenderness around the eyes and cheekbones
- pounding in the ears
- shivering
- slow or fast heartbeat
- sore mouth or tongue
- sore throat
- sweating
- swelling
- trouble with sleeping
- troubled breathing
- unexplained weight loss
- unusual tiredness or weakness
- vomiting
- white patches in the mouth or on the tongue
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
- Arm, back, or jaw pain
- confusion
- dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
- fainting
- fast or irregular heartbeat
- fast, slow, pounding, or irregular heartbeat or pulse
- seizures
- shakiness in the legs, arms, hands, or feet
- sleeplessness
- trembling or shaking of the hands or feet
- unable to sleep
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
- Acid or sour stomach
- anxiety
- belching
- blistering, burning, crusting, dryness, or flaking of the skin
- bone pain
- burning, dry, or itching eyes
- difficulty with moving
- discharge or excessive tearing
- eye redness, irritation, or pain
- headache, severe and throbbing
- heartburn
- hives or welts
- indigestion
- itching, scaling, severe redness, soreness, or swelling of the skin
- mouth or tooth pain
- muscle cramps and spasm
- muscle stiffness or tightness
- redness of the skin
- redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
- skin rash
- skin rash, encrusted, scaly and oozing
- stomach discomfort, upset, or pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 2019 Truven Health Analytics, Inc. All Rights Reserved.
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Making sense of C02 data: A Microsoft/Berkeley collaboration
In this podcast, MSR researcher Catharine van Ingen and Berkeley micrometeorologist Dennis Baldocchi talk with Jon Udell about their collaboration on www.fluxdata.org, a SharePoint portal to a scientific data server. The server contains carbon-dioxide flux data gathered from a worldwide network of sensors, and provides SQL Server data cubes that help scientists collaboratively make sense of the data.
Dennis Baldocchi is a professor of biometeorology at Berkeley. His research focuses on the physical, biological, and chemical processes that control trace gas and energy exchange between vegetation and the atmosphere. He also studies the micrometeorology of plant canopies.
Catharine van Ingen, a partner architect with with Microsoft Research in San Francisco, does e-science research exploring how database technologies can help change collaborative research in the earth sciences. She collaborates with carbon climate researchers and hydrologists.
JU: Dennis, you're someone who's pulling together a worldwide network of CO2 monitoring stations. Can you briefly explain how these devices work?
DB: Sure. Let me give you a bit of history. Back in the late 1950s, David Keeling made some of the first measurements of carbon dioxide concentration -- on Mauna Loa in Hawaii, in the Arctic, very remote locations. They saw an increase in the C02 concentration in winter, and a decrease in summer. The increase is due to respiration in the biosphere, the decrease is due to photosynthesis. And on top of this they saw a trend due to fossil fuel combustion and logging of tropical forests.
These measurements were just C02 concentrations. As atmospheric scientists, we know that changes in the atmospheric concentration are due to fluxes. We measure actual fluxes: moles of carbon dioxide, per meter squared, per second, between the atmosphere and the biosphere.
We do it with a combination of sensors. One is a three-dimensional sonic anemometer, which measures up-and-down and lateral-and-longitudinal motions of the air, ten times a second. And simultaneously with new sensors we measure instantaneous change in CO2 concentration.
JU: So it's a combination of sensing wind speed and sensing atmospheric gas.
DB: Absolutely. We measure a covariance between the two, and theoretically that's related to the flux density.
JU: And this population of sensors has been growing for 15 or more years?
DB: Yeah, my old lab in Oak Ridge, Tennessee made some of the first sensors we were using in the early 90s. Around then a company called Licor started making a sensor that's about 15 centimeters long and shoots an infrared beam from source to detector. The air can blow through this sensor, and it's low power, doesn't need pumps, so it can be deployed in the middle of nowhere. Many of us run with solar power, so we have a PC that pulls an amp, then the sensor pulls another amp, so for two amps we can run a flux system.
JU: As Catharine points out, there's a long tradition of large-scale collaboration in some scientific disciplines, but it's relatively new in other areas, and it sounds like this is one of those.
DB: Yeah. I was a grad student in the 80s and I remember my professor having a desk full of data. People would knock on the the door wanting to borrow it, and there was always some reluctance, it was really a single-investigator culture at the time.
In many ways I credit our Italian colleagues, they were really gregarious and good at hosting wonderful workshops that started bringing people together.
JU: So Catharine, how did Microsoft get involved in building out the scientific data server that supports this project?
CvI: It was serendipity. We had met folks at the Berkeley Water Center two ways. First through Jim Gray's interest in e-science and database applications. Second, one of the current heads of the Berkeley Water Center is an old friend of mine from grad school, Jim Hunt. We were talking about doing a hydrology project, then somehow my colleague at BWC on the computing side, Deb Agarwal, ran into Dennis, and we started talking.
Dennis fit all of the criteria for how I like to engage with scientists. He was desperate, he had a problem that he didn't know how to solve, and that was important, because it meant he was willing to talk to us and teach us things.
Also he had enough data to make things interesting for us. It's not petabytes, but we're talking about the hundred-gigabyte range, and the dataset is extremely diverse. I find it fascinating from an informatics point of view because it's a true scientific mashup to do the data analysis. You're taking the flux data that Dennis just described, as well as a lot of site properties, and other things from the literature, and trying to bring it all together.
JU: There's a whole range of what you folks call ancillary data, which describes soil and vegetation and other aspects of the environment.
DB: To give you an example, the meteorological data, from a database point of view, is fairly simple and regular. Our loggers give us half-hour data, so you get what's essentially an Excel spreadsheet. The rows are timestamped for each half-hour, and the columns are temperature, flux of water, solar energy, and so on. But it gets complex when you weave in the ancillary data. For example, you need to know the population of leaves that control these fluxes. You may measure that in a half-dozen spots, a half-dozen times per year. Then you need to understand leaf photosythesis, and that's another set of measurements, and then soil texture, carbon, and water absorption, and all these measurements are at different depths, different times, it gets really complex.
CvI: Another interesting aspect, from our side, is handling time. We all think time is linear...
DB: [laughs] Not according to Einstein...
CvI: [laughs] ... well ... so, since we're dealing with plant information, plants photosynthesize during the day. So rather than using wall-clock time, using the plants to tell us about day or night was really fascinating. In effect we're deriving a time window based on the time series data themselves, and for informatics folks, this was more fun than a barrel of monkeys. We've generalized the concept now, and applied it to a couple of other disciplines. Handling time has turned out to be one of the biggest areas of learning.
JU: So what is FluxNet, actually, and how does the data get into the scientific server that you've built?
DB: It started at a workshop we held in Italy in 1995. From that, regional networks started blossoming. First off the ground was the EuroFlux network, then AmeriFlux in about 1997, then over time the Asians, the Canadians. NASA funded us for two cycles, and then things dried up as they decided to go to the moon and to Mars. Most recently we've been funded by NSF, which is funding a whole bunch of ecological networks. On the side, there's been funding to Oak Ridge National Lab, through NASA, to maintain the data acquisition and archive system. And then Deb and Catharine joined in to build value-added products through this FluxData project.
Sometimes I think we're like Tom Sawyer, we've got this fence to paint and all these people are helping us paint it.
JU: Or like stone soup.
CvI: It is like stone soup. From an informatics point of view, the way we think about it is that the data starts with tower owners -- and Dennis is a tower owner as well as a project overseer -- and flows to one of the network repositories, or directly to Oak Ridge where the data is stored.
JU: OK, so your site, www.fluxdata.org, is not the repository, it's for analysis...
CvI: Yes. There are data archive centers, funded primarily by NASA, where you can contribute data, and where data is stored. The challenge for the scientist is to get from the raw data to the science, it's a classic last-mile problem. So the data flows from the repositories to the folks in Europe who are doing gap-filling and uniform processing, and it flows back to Oak Ridge for long-term storage, and it flows to us.
We then make it available to researchers to download, and we provide the value-added summary products. So we're not at the front end gathering data, and we're not the archive, we're in the middle, solving that last-mile problem.
JU: Part of that solution is to put the stuff into data cubes. Dennis wrote somewhere that while these have been used in financial analysis for a long time, their application to scientific analysis is new. It might surprise some people to learn that this way of looking at data isn't common in the scientific world.
CvI: It actually isn't. OLAP databases, data cubes, have been around for a long time. I think I first saw one in the early 90s. But that was really commercial data, it was about finding how to make coupons for Oreos and milk. Scientific data is different in a couple of respects. First, it's much more dense. You tend not to always buy Oreos and milk together, but Dennis always reports CO2 flux, temperature, and precipitation together. The other difference is that a lot of the analysis for commercial data is not at the leaf nodes, it's about annual sales. Whereas a lot of science is actually at the leaf nodes, it's about looking at statistical variation in the half-hourly data.
So we end up building different-shaped cubes.
DB: And let me add that we'll present this data with gaps, for several reasons. One is that if there's a thunderstorm, it might cause the instrument to malfunction. Another is that we have to comply with meteorological steady conditions -- for example, steady winds. So we apply a lot of quality assurance to the data set, and that produces gaps, but any user of the data wants a continuous record. So we need to find ways to fill those gaps.
We also want to partition the fluxes, so we can understand mechanisms. We measure the net ecosystem exchange, but there's a component due to photosynthesis and a component due to respiration. By separating out day and night data we can derive these components, so there's all this value added to the data from the archive.
JU: So I looked at some of your pivot tables, for example on sites by vegetation -- how are those being used?
DB: To do cross-site analysis. For example, we're interested in how length of growing season may affect net carbon exchange. When I did this analysis before I met Catharine, I had to open a bunch of spreadsheets and cut and paste, cut and paste. With the cubes, you press a button and the data's there. It really allows you to do a lot of quick what-if questions, and be creative. It makes our work quicker and easier.
CvI: We're also doing a fair amount of sorting. You can sort along vegetation types, to see the difference between croplands and grasslands. We also know each of the sites that is a boreal forest, so you can look at just those, or just tropical forests. If the database has 900 site-years, you can select just the 200 that you need for a piece of analysis.
JU: Is it fair to say that until this was brought together it wasn't possible to do this?
CvI: It was possible, but just really tedious.
DB: Back when the network was small, we did a workshop in 2000, and we had about 100 site-years of data from 30 sites. It was easy to be clunky. But now we have 900 site-years from 400 sites, and you just can't use the old methods. We have to go modern.
JU: What kinds of collaboration effects are you seeing? You've written that it's a big challenge to motivate scientists to contribute the ancillary data in a standard way. Getting the stuff in front of people like this, in a common presentation with explanations about what all the variables mean, and how to report them, should help get everybody onto the same page.
CvI: I see a couple of things. First, we're starting to hear from individual tower owners asking us questions, and telling us what's wrong. "I'm sorry, my site isn't really at that lat/lon." Or: "My leaf index is really this."
They see their data being used in papers: we're hosting access for about 60 paper-writing teams. As the papers come to fruition, we're actually tracking what sites they're using, so it's possible to go in and find out who's using your data.
DB: It's motivating. I know my post-doc is so excited when she finds out people are using this data.
JU: That explains why you have an update feature on the site?
CvI: Absolutely. We know there are corrections that need to be made. Treating it as a living, breathing data set, and being able to respond in an organized way to changes...
DB: As more eyes look at it, they can help us fix it. Especially our own data. You look at it and don't see the problem, but when someone tries to use it...oops. In fact we found a problem with our solar heat flux recently. We were doing the correct calculations from 2000 to 2003, then we changed algorithms, and the staff changed, and all of a sudden there was a glitch in how the data were being processed. Finally some scientist from UCLA wanted to use the data, and he plotted it up, and found the problem. So now we're correcting that.
CvI: One of the things that happens when you plot data over time is that you can see any errors in time reporting. One site was off by a couple of months. The data looked fine when you plotted just that site. But if you plot it by nearby sites, suddenly you see the problem. That's the kind of processing -- bringing the data into focus -- that we're engaged in right now.
JU: So you've got the data online, and tools for viewing and updating the data, but there's also a conversational infrastructure. You have a blog, there are places for people to add comments and have discussions, and all of that is kept together with the data. Catharine, you've said that the role of data curation in science is emerging, and will be key as we increasingly see these mega collaborations with hundreds or even thousands of people working on the same data. You need an environment in which those conversations can be centralized in the same way the data is centralized.
DB: There's also almost a traffic-cop role too, just to avoid redundant efforts. There are several obvious ideas, and multiple groups may want to pursue them. In the long run it's a waste of effort if people are doing the same redundant analysis, and only one paper may get published. If we can get these people to talk to each other, and interact, that's critical.
JU: As Catharine puts it, investing the same effort in publishing data as you would in writing a paper is something that's not yet socialized.
CvI: No, it's not. We see again and again how difficult it is to put the data in a box and tie a bow around it, so people can reuse it. It's very hard, but very important, long-term, for a lot of these environmental problems.
DB: So Catharine, by marking these data sets and giving them some kind of provenance, is this a way scientists can get credit for the work?
CvI: Well, the challenge isn't only enabling that, but also teaching the funding agencies that it's just as important.
JU: Exactly. I've talked to Timo Hannay about this -- he's the guy who runs the web stuff for Nature Publishing -- and this is a huge interest of his. Science is an enterprise that runs on people getting credit for publishing papers, not data. I gather that often papers are published as a thin gloss on a data set, just to get the data out there. There hasn't been a model for publishing the data itself. The fact that the data from somebody's individual tower can be traced back, and then traced through its use in follow-on papers -- that's huge. Your post-doc can not only get excited about other people using her data, she can get credit for their citations of it.
JU: So, the climate effect of C02 is obviously a hot topic. What have we actually learned at this point?
DB: One paper used this network in combination with remote sensing to see how carbon exchange across Europe responded to the drought and heat wave in 2003. So here was this network poised to measure how the whole biosphere responded to this climate assault.
The network has also been successful with what we call emergent scale processes. One that came out strongly is that plant canopies respond to light more efficiently if the light is diffuse, as opposed to when there are clear skies. That's a process we haven't seen before.
Another thing we found, because we have continuous records, is that if there's a summer rain event, microbes turn on immediately and produce huge amounts of respiration that we never envisioned before. Scientists in the past would miss these extreme events, but by having continuous measurements we can see how the system responds.
JU: But you wouldn't argue for long-term trends in the 15 or so years of data you've collected?
DB: If there are long-term trends, they seem more related to ecosystem dynamics. Many of the forests under study were disturbed at the turn of the century, so they're going through that natural cycle of growth, maturity, and decay. Those ecological features lay on top of any potential climate trends.
JU: So it's more about having an infrastructure in place that allows us to have the data in hand, and then make some predictions?
DB: Yes. Now in fact, one of the things we are seeing is a change in the length of the growing season. As things have gotten warmer, the spring comes earlier, and it's really affecting carbon uptake in the citrus forests. But the big unknown is that if you have an earlier spring you might also get a summer drought, so you have an increase in carbon in the spring, and a decrease in summer, and the two factors may cancel out. But with our measurements we can see the mechanisms, we can understand and parse out what's happening and why. Whereas in the past, scientists would cut down trees and get tree rings and take one integrated snapshot for the whole year. But they wouldn't understand why, because those tree rings were also affected by drought and temperature and ozone and elevated C02 and other issues.
CvI: It's really a great time to be doing this stuff, because you're at the juxtaposition of social need, scientific need, and the availability of cheap technology.
DB: And our NSF grant encourages to do outreach, so this is a great opportunity to do that.
CvI: Jim Gray always used to point out that the post-docs are the ones in any collaboration who most embrace new technology, and move the entire collaboration forward. Knowing the guys over in Europe that's certainly true, and you can see it happening with your own post-docs, Dennis.
JU: So how are these cubes getting built, Catharine? What was the collaboration between you and the scientists?
CvI: We're lucky to be starting with a data set that is very well processed. As to building the rest, Dennis gave us, gosh, I looked at 300 hundred of his graphs. I also got a similar collection from two of his other colleagues. I went through all the graphs and papers to try to understand how the data is manipulated and displayed.
DB: That's a good idea. I didn't realize you did that.
CvI: Oh yeah. [laughs]
DB: That would be helpful, because you see the kinds of products we're trying to create from these databases.
CvI: Absolutely. I started by classifying the graphs into time-series graphs, scatterplots, and then everything else. Then I waded through how everything was sorted, searched, filtered, trying to figure out how to organize the data to enable that class of graphs.
DB So Catharine, there are a bunch of graphs I'd like to replot with this new database.
CvI: Well Dennis, you and I should have lunch and we should figure out how to rip out a bunch of graphs.
So, along the way we realized that scientists will often make 50 graphs, through away 48, and keep two. The ability to make a lot of graphs rapidly and simply usually requires some kind of scripting, and that's where you start leaving Excel and going into MATLAB or another scientific analysis tool.
DB: Yeah, I'm using MATLAB a lot nowadays, and I'm seeing things I never saw before. I like having the script files because it gives me some history of what I was looking at.
CvI: That's why we decided to connect MATLAB to the cube, so you can browse the reports we make in Excel, or go directly through MATLAB. Again, it's solving that last-mile gap to the scientist's house.
JU: Well this has been great, thanks!
DB: Yeah, thanks. Catharine, we should get together and talk about some graphs.
CvI: Thanks Jon. And thanks Dennis. Are you in your office? I'll call you later this afternoon.


text:
RIM's new BlackBerry 10 mobile operating system looks good and SAP plans to begin supporting RIM handsets for its workforce shortly after the January launch, an SAP executive said yesterday.
BlackBerry, once a darling of the corporate world, has seen usage slip among business users at major companies in the past couple of years as it has struggled to keep up with Apple and Android devices that workers have found more desirable. But the company hopes that will all change on January 30 when it launches the new BlackBerry 10 operating system and an unknown number of handsets.
"I believe there is still a community of BlackBerry users out there," said SAP CIO Oliver Bussmann at CES in Las Vegas. "They love it."
SAP, based in Walldorf, Germany, has around 55,000 employees worldwide and already manages a complex ecosystem of 20,000 Apple iPads, a similar number of iPhones, and 4,000 Samsung Android handsets. Among its user base, it has about 16,000 BlackBerry users, he said. SAP is a beta tester of BlackBerry 10.
"RIM needs to do a good job on execution of the launch, better than the PlayBook," he said, referring to RIM's tablet PC that was introduced in the shadow of the iPad in 2011 but failed to take off. "The first indications are that they are and it's looking good."
"The same is true of Windows Phone 8," he said. SAP is already supporting Microsoft's new cellphone operating system for its more than 55,000 employees around the world.
Getting new devices supported quickly is critical in today's fast-moving electronics industry, he said. It's much better for a company to embrace BYOD (bring your own device) and let employees use the phones they want.
"As CIO, you can ignore these new devices, but then the chance employees will find a way around corporate restrictions is high," he said.
Thus SAP's plans to quickly support and offer the BlackBerry 10 handsets to its users.


text:
Stable Channel Update
33 comments :
Thanks goodness! I needed the webkit fix for zooming, and I finally have it.
My name has been spelt incorrectly in the report, it's Subodh Iyengar and not Subodh Iyenger. Would appreciate if you could correct that in this and the CVE as well. Thanks.
- This comment has been removed by the author.
everything was working so well but of course something had to break:
Catalyst 12.4
"Log Messages
[2396:2844:0110/211121:ERROR:gpu_video_decode_accelerator.cc(169)] : NOT IMPLEMENTEDHW video decode acceleration not available.
[784:3520:0110/211152:ERROR:gpu_info_collector_win.cc(91)] : Can't retrieve a valid WinSAT assessment.
[784:3520:0110/211152:WARNING:amd_videocard_info_win.cc(29)] : Unable to load aticfx dll."
Tested with a 1080p .mp4 from YT.
Would you mind looking into this?please?
Thank you.
My full chrome://gpu-internals report can be find below:
it has crash with windiw 7 x64
i can not use version 24. iuse old chrome .exe v23.
v24 crash while visiting websites.
please help me.
I experienced with latest version many crashes...i cannot visit many websites...returning to version 23, everythink fine. What happen in the latest 24 version ???
In Chrome 24 i notice there is considerable lag when i first time switch to some tab, after that switching to tab is instantly, fine in Chrome 23
Oh my god! Update failed.
So I uninstalled Chrome. Then download again the latest installer... and installation failed!
Here I'm am, back to Internet Explorer :'(
I fix the lagging by disabling Use GPU composition on all pages in about:flags
The problem of GDI leaks survives... yet :'(
This is the first time I have truly had an issue with Chrome.
The lastest version 24 update will not work on Win7x64. The browser will crash all the time.
I have tried disabaling extenstions and plugins, using a clean profile, and reinstalling from scratch. The only thing that worked was reverting to version 23.
I have the same crashes here (Win7 64bit). Where can I download the latest Chrome 23?
Ahh, Filehippo is really great! :)
Was hoping an update would be 64-bit. When do you guys think it will it be 64-bit so I don't have to go to a different browser to watch Netflix?
- This comment has been removed by the author.
With 24 version ::-webkit-scrollbar in CSS doesn't seem to work properly anymore.
In 23 I had a proper grey scrollbar displayed.
But in 24 I have a black rectangle displayed where the scrollbar should have been.
Code sample visible here : http://pastebin.com/vU3uSUJu
I can also confirm, Chrome crashes on Win7x64 spanish. Two computers were updated today, both are not able to use Chrome as it crashes immediately after opening any site, even www.google.com
I have Win 7 64 bit and it works fine now, but i have to disable GPU composition on all pages in chrome://flags, try it, it may help
What`s wrong with chrome://history in this version? It seems like just the last XY visited pages is recorded, not all of them. "Show older" button on the bottom of the site is simply missing. Can anyone reproduce this?
Windows 7 SP1 fully updated
My computer is running on older hardware and beginning with the last two updates (post 23) I started experiencing a lot of stuttering and lag. Zooming windows (maximizing and minimizing) stuttered terribly, and chrome even affected my video player.
Thanks to 24 making everything even more intolerable, I luckily found a thread and learned to use these command line switches:
--disable-gpu --disable-software-rasterizer
Now everything is buttery smooth again!
Hm, the crashing issue is obviously fixed in the actual dev version of Chrome 25 (25.0.1364.29)...
I started seeing problems when Chrome jumped to 24.xx from latest stable 23.xx . I saw the comment about disabling GPU compositing and tried it. It fixed the issue I was seeing. When I clicked on a tab it showed the correct URL but the content was showing the tab I was on. WIN 7 64bit, GTS450 driver 306.97
I`m having the same deepblu said:
When I clicked on a tab it showed the correct URL but the content was showing the tab I was on.
I disabled gpu but now I can see the page composing everytime I change pages... its no more instantaneous..
and its not because my pc config...
Release 24 of Chrome broke the use of XMLHttpRequest for the download of binary files. Many used overrideMimeType to specify "text/plain; charset=x-user-defined" as the content type, thus avoiding the automatic interpretation of the character stream, and relied on the response content type header to determine the actual mimetype.
Chrome up to 23 saved the original mimetype in the response's Content Type, regardless of what was overridden through overrideMimeType. This is consistent with past and current versions of Firefox and Safari (Explorer never supported overrideMimeType).
With release 24, the content type of the response is whatever was specified as overridden, making it impossible to download binary files as charset=x-user-defined, and then discovering through the content type what was the original mimetype.
This is broken, broken, broken, broken. I have created a page that shows the issue:
Please use it with many different browsers.
Consider for instance the situation in which server-side documents are accessed that are in either XML, JSON or ZIP format (including MS Excel and OpenOffice files): if I do not specify overrideMimeType, the XML and JSON files work fine, but ZIP files (including Excel and OpenOffice) are corrupted. If I do specify overrideMimeType, I am unable to distinguish XML from Json from Zip files unless looking into the content of the file (hardly elegant).
This worked up to 23, and still works on Safari and Firefox, and has stopped working in 24. Please help.
Thank you
Fabio Vitali
I started having problems with CORS pre-flight HTTP OPTION request from Ajax. It was working fine before. I think this issue is related this Chrome update.
I am stuck. I don't know how to roll back to the previous version of Chrome to confirm this issue with the current update, but as far as I know nothing else has changed.
Please help
Veer Muchandi
CORS preflight request - HTTP OPTIONS command fails with 'Load cancelled' in Chrome. It was working before. It works on Iron.
So it is an issue due t the last update.
Please fix it.
Something has been done to touch since it works erratically now, like it has focus issues, sometimes switching tabs randomly at tap and other times doing nothing at all. Win7 64, with HP tm2 (pen+touch). And yet still have to use plug-in flash..
Sound problem with HTML5 Video !!
Glitches, cracks, sound distortion.
Since 24.0.1312.45. With .52 also the problem.
So not stable at all with new technology !
flash permanently crashes on YT
Today BEFORE updating to 24.0.1312.56 m, all my Chrome browsers on computers with Win7 x64 began working again. Obviously the problem was not related to .52
recurrent hard disk activity (every 3 secs) with Google news page. Only happens with this version of Chrome (not in any other browser either).


text:
Thursday, September 25, 2008
The long goodbye
And so, we watched last night as A.J. Burnett pitched a dilly of a game against the Yankees' B squad, then strode off the mound for what in all likelihood was his last appearance as a Jay at the Rogers Centre.
Over his three years with the franchise, A.J. was a big huggy bear who was often the first Jay off the bench to offer a loving clinch to whatever pitcher was walking off the field. So it made sense that the entire expanded roster lined up last night to welcome A.J. after his 11 strikeout performance with a last meaningful hug for the enigmatic hurler.
(And was it just us, or did Roy Halladay's hug linger a little longer than most? Doc can pull that off, because he's twice the man that we'll ever be. But we digress.)
Last night's swan song might have been a little easier were it not Shaun Marcum's injury. We were pretty comfortable in the notion that A.J. was going to bugger off and get ridiculous money from someone, and that the Jays would be better off plowing those sorts of dollars into a hitter. But with Marcum out until 2010, the remote notions that maybe (just maybe) the team could make a play to keep him here for a few more years started to get floated out there.
And damn it if we didn't start to internalize them ourselves. We're a sucker that way.
We don't exactly know what to make of A.J. Burnett's stay in Toronto. His arm troubles through his first two seasons were agonizing and suspect (remember the "sharks in my elbow" comments?), but at the same time, Burnett was the sort of pitcher who could bring you out of your seat with his stuff.
Moreover, he was a character and brought some semblance of personality to a team of taciturn strong silent types. Sure, we pissed on Burnett's shaving cream pies and his races against various Mexican food products, but we quietly laughed along with his antics. It was (dare we say it?) just A.J. being A.J..
If he's truly gone (and it is ludicrous that we are even holding out hope that he'll stay), then we're going to miss him.
14 comments:
- eyebleaf said...
he was a beat against the Yanks and Sox this season. that's what i'll miss most, his domination against the empires. he was fighting the good fight against evil.
i thought vernon was 100% gone when he hit the market. perhaps AJ might stay, and perhaps it will be Doc that goes a long way in making that happen.
and you're right, he was a character. we need more of that. do we take a chance and show him the money like rod tidwell? it's a tough call, considering he's never thrown this many innings, ever. i'm worried he's due for a stint on the DL. but not worried enough to not want him back. i love him.
fuck, i'm rambling.
and doc's 10 times the man i'll ever be.
- September 25, 2008 at 12:03 PM
- Brendan said...
Real men are comfortable enough with their sexuality to hug in any situation.
Pat Hentgen came back to us. I wouldn't have hugged him though, that's just gay.
-signed anonymously by the sexually confused anonymous guy-
- September 25, 2008 at 2:16 PM
- Tao of Stieb said...
Err...brendan? You realize that you are not anonymous, right?
So gay.
Also, we prefer not to think of that Hentgen return to the Jays. Seeing him in the stupid black Jays cap just makes us sad.
Like David Lee Roth rejoining Van Halen.
- September 25, 2008 at 2:25 PM
this blog sucks.
- September 25, 2008 at 2:29 PM
- Tao of Stieb said...
You suck.
- September 25, 2008 at 3:12 PM
- The Ack said...
You know, I was listening to the broadcast on the radio when AJ was getting pulled, and Jerry & Alan's description of the event (the interaction between Cito & AJ on the mound, the fan reaction, the curtain call, the hugs) gave me goosebumps - seriously.
Is that lame?
Fuck you if you think that's lame.
- September 25, 2008 at 4:15 PM
- September 25, 2008 at 4:47 PM
AJ is a mouthfucker, but he's our bitch! AJ is a Jay, not a Fish no doubt! Bring him back. And to the anon making snide comments, cocksucker go blow Jeter! Or better yet blow asshole mouth Papelbon. Capish? If not go back to Massholia and spread your asscheeks for Big Flappi, that big fat beast.
- September 25, 2008 at 5:25 PM
- Darren Priest said...
If we're going to break the bank to keep AJ couldn't we at least kick the tires on Sabathia?
Play a little, CC! (betch you can't place that reference)
And this blog sucks...my time when I should be working, that is!
- September 25, 2008 at 5:31 PM
- The Ack said...
- September 25, 2008 at 5:34 PM
- MK Piatkowski said...
I went trolling around the net today hoping that someone posted on video the walk-off, hugs and curtain call. Lame sportsnet.ca has an after-game interview that's pretty cool but no footage of this moment.
Does anyone know where to find it?
- September 25, 2008 at 6:48 PM
- MK Piatkowski said...
Finding audio of Alan and Jerry calling it would be good too.
- September 25, 2008 at 6:56 PM
fuck it. pay the man whatever it takes.
- September 25, 2008 at 7:42 PM
ROY OWNED today.
His hug with AJ was for more than 10 seconds wasn't it.
Am I gay for timing it?
- September 25, 2008 at 10:40 PM


text:
U.S. Securities and Exchange Commission
Litigation Release No. 21815 / January 14, 2011
SEC v. George H. Holley, Steven V. Dudas, and Phairot Iamnaita, Case No. 3:11-cv-00205-MLC-DEA (D.N.J.) filed January 13, 2011
SEC Charges Former Chairman of Home Diagnostics, Inc., and Two Business Associates in Insider Trading Scheme
The Securities and Exchange Commission yesterday charged the former Chairman of the Board at Home Diagnostics Inc. with illegally tipping friends and business associates with inside information about an impending acquisition of the company.
The SEC alleges that George H. Holley, who co-founded Home Diagnostics, provided his personal accountant Steven Dudas and his friend and business associate Phairot Iamnaita with confidential information about the company's upcoming acquisition by Nipro Corporation. Holley then gave Dudas $121,500, which Dudas and Iamnaita used to purchase Home Diagnostics stock in a joint brokerage account. After the acquisition was publicly announced, Dudas and Iamnaita tendered their shares for an illicit profit of approximately $90,120. Dudas and Iamnaita are charged along with Holley in the SEC's complaint filed today in federal district court in Trenton, N.J.
The SEC alleges that in addition to tipping Dudas and Iamnaita between December 2009 and Jan. 13, 2010, Holley illegally provided two other friends, a relative, and a business associate with inside information about Home Diagnostics's imminent acquisition. Holley provided at least two of these individuals with a cover story, giving them copies of analyst reports and telling them that they should use the reports to justify their illicit trading. All four of these individuals purchased Home Diagnostics stock on the basis of Holley's tips for combined profits of more than $170,000.
The SEC's complaint charges Holley, Dudas, and Iamnaita with violating Section 10(b) of the Securities Exchange Act of 1934 and Rule 10b-5 thereunder, the general antifraud provisions of the federal securities laws, and Section 14(e) of the Exchange Act and Rule 14e-3 thereunder, the tender offer fraud provisions. The Commission seeks permanent injunctive relief, disgorgement of illicit profits with prejudgment interest, and the imposition of monetary penalties against all defendants. The SEC also seeks to permanently prohibit Holley from acting as an officer or director of a public company pursuant to Section 21(d)(2) of the Exchange Act.
The SEC thanks the U.S. Attorney's Office for the District of New Jersey, the Federal Bureau of Investigation, FINRA, and the Securities and Exchange Commission of Thailand for their cooperation and assistance in this matter.
The SEC's investigation is continuing.


text:
straw(redirected from Agricultural byproduct)
Also found in: Dictionary, Thesaurus, Encyclopedia.
1. mature, dry foliage of a cereal crop after the grain has been harvested by a header or by threshing. Has very low digestibility, energy and protein content. Used principally as bedding but in some economies is used as feed. Causes impaction of the rumen in cattle and ileocecal valve in horses. Is more digestible if chopped and fed with a protein supplement or urea. If left standing in the field is referred to as stubble. When fed in this way there is a variable amount of spilt grain available also.
2. a hollow, plastic tube used for the storage of frozen semen. See also french straws.
straw eating
a vice in stabled horses which may require muzzling to avoid the occurrence of impaction colic.


text:
Sally Gammon: Facing the Future
Recently, I announced my intention to retire as President & CEO of Good Shepherd Rehabilitation Network in July 2013. (Click here to read the press release). Since the announcement, I have received numerous well wishes as well as some thoughtful questions regarding the future – my future, the future of Good Shepherd and the future of health care.
First, in regard to my future, I am moving into this next phase of my life knowing that my health is good and my ability to contribute to the community remains high. I am excited about having the time and opportunity to expand my involvement in causes that I am passionate about.
I have been at the helm of Good Shepherd for more than 15 years, the longest-tenured position of my career, in large part because my work has always been rewarding and enjoyable. It is for this reason that I plan to remain involved with Good Shepherd after retiring from my current position.
The Future of Good Shepherd
The Board of Trustees is conducting a national search for Good Shepherd's next President & CEO, who will be charged with continuing to move the organization forward.
Good Shepherd is well positioned for a successful future in the Lehigh Valley and beyond. Since 1997, Good Shepherd has quadrupled in size, scope of services and budget, going from a $45 million to a $201 million organization. We added inpatient and outpatient facilities and new services as well as took on rehabilitation management contracts at other hospitals and assisted living centers. Since 2008, GSRN has been majority owner of Good Shepherd Penn Partners, our joint venture with Penn Medicine in Philadelphia.
When you combine the Allentown operation with the Philadelphia operation, GSRN has 412 inpatient beds, 34 outpatient sites and more than 2,000 employees.
The Future of Health Care
Good Shepherd's next President & CEO will lead the organization through the changes and challenges of health-care reform. He or she will need to ensure that Good Shepherd continues to provide comprehensive post-acute care that produces outstanding outcomes for our patients, while delivering that quality care as cost effectively as possible.
The growing ranks of the aging baby boomers and other future patients are projected to increase the demand for physical rehabilitation. To meet that demand, Good Shepherd's next President& CEO will need to embrace and promote Good Shepherd's core value of partnership, which is vital to the organization's growth and to an efficient continuum of patient care.
The opportunities and challenges facing Good Shepherd's next President & CEO are many, and I have no doubt that Good Shepherd's Board of Trustees will choose an impassioned and visionary leader with the experience and expertise vital to ensuring Good Shepherd's viability into the future.
Be assured that my commitment to Good Shepherd will remain high, and I will make this leadership transition as smooth as possible. I look forward to a productive and exciting future for myself and Good Shepherd.