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Maher & Maher is a specialized change management and workforce development consulting firm that delivers tailored solutions to public sector organizations and commercial clientele. Now in our 31st year, the firm is known for innovative organizational development solutions that focus on managing change, fostering collaboration, process improvement, specialized training, message customization, e-Learning strategy and design, and executive and work group facilitation.
Maher & Maher is seeking a highly motivated and experienced Education Program Manager to join our team to support our government clients. The Education Program Manager will have a leadership role in the practice with a focus on expanding Maher's portfolio of contracts within the Education sector and to provide oversight and subject matter expertise on a variety of Federal government projects. This position will have a wide range of responsibilities including business development, project scoping and oversight, client management, and team leadership.
The successful candidate will leverage existing relationship to identify and influence potential customer opportunities and provide quality input to proposals by capturing customer interests and needs to achieve Maher's growth goals within the Education sector.
To learn more about Maher & Maher, visit www.mahernet.com
Develop and implement Maher's BD strategy in the Federal Education sector
Work with multiple stakeholders providing leadership and subject matter expertise on projects
Leverage Maher's established capabilities and expertise in Technical Assistance and Training including virtual technical support, Integration of Services, Work Force Development, Apprenticeship, Career Pathways, K-12 and Community Colleges
Leverage knowledge of the Department of Education market and budget, existing DoEd relationships, and knowledge of industry market research tools to develop, manage and capture a pipeline of opportunities to meet DoEd account growth goals
Develop, articulate and execute strategic and tactical plans as well as specific capture efforts in Federal Education Sector
Identify and cultivate teaming partnerships and business alliances in the Education sector
Provide oversight and leadership to proposal process and write proposal content
Education, Knowledge, and Experience
Bachelor's degree required
Master's degree in a related field (such as Adult and Continuing Education, Youth Education and Development, Public Administration, public policy, business administration, or related field) is preferred, but not required
At least 10 years of experience leading complex projects in the areas of adult education, career and technical education, adult learning theory and/or curriculum development with at least 3 of these years working directly with the Federal Department of Education
Proven experience managing complex projects, including project budgets, and teams
Previous experience with technical assistance and training activities
Excellent communication skills (oral and written) with ability to express complex ideas clearly
Highly organized and detail oriented, with strong analytical capabilities
Successful track record of developing leads, proposal development, and winning contracts with the Department of Education.
Familiarity with federal acquisition vehicles such as FedBizOps, GSA e-Buy, contracts and GSA schedules
A self-starter with the demonstrated ability to lead project activities
Ability to manage work on multiple, concurrent projects
Resourceful and capable in anticipating problems and effectively resolving challenges
Ability to interact effectively with individuals at all organizational levels
Capability to build and maintain strong client relationships, with a focus on customer satisfaction
Ability to work effectively as a member of a diverse team
Ability to be flexible and adapt to changing priorities
Ability to understand, develop, and monitor project budgets
This is a remote position ideally based in the Washington, DC area. Candidates not based in Washington, DC will be considered, with the understanding that regular travel to the area will be required.
To apply, please visit https://careers-impaqint.icims.com/jobs/2153/program-manager--education---maher-%26-maher%2c-an-impaq-company/job
Maher & Maher is an Equal Employment Opportunity (EEO) employer. It is the policy of the Company to provide equal employment opportunities to all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.


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Silver glitery shoes
Size 5. Never been worn. Good for occasions. Good condition.
West Midlands in England (United Kingdom)
Dkny handbag
Dkny handbag in perfect condition only used twice, no marks what so ever
Gloucestershire in England (United Kingdom)
BRAND NEW TOP QUALITY HERMES BELTS £25 2 for £45
25 2 for £45 (Special Offer)Tan/BlackWhite/blackDark brown/black Orange/blackRed/blackNavy/blackPink/Black*All size*Brand new*Leather*SerialAMAZING BIRTHDAY AND GIFTS! AlSO TREAT YOURSELF!!100% Reliable Top Seller 5* TrustedPosted Anywhere in UKPaypal/Bank transfer/CollectionPlease Call or Txt======...
London in England (United Kingdom)
Genuine tag heuer f1 edition
Here is my tag heuer f1 edition watch. As tou can see from the pic this is a stunning watch.The watch is 100% genuine and not a copy.Gutted to be having to part with it but needs must.
County Durham in England (United Kingdom)
Boots size 3
I have a boots for sale, wear just few times, size 3. In perfect condition.
Cambridgeshire in England (United Kingdom)
Collection of 13 X NEW Leather Belts - various sizes
13 new leather belts ex shop stock including:1 x 36" Made in England Real Leather - DUTCH JEANS (Black) Plain1 x 36" Made in England Real Leather - Original Jean Belt (Black) Plain1 x 36" Real Leather Watsons (Brown) Plain1 x 46" Real Leather Made in Greece (Brown) Stitched1 x 43...
Bristol in England (United Kingdom)
Nike size 5 Cortez.Brand new never been wornWhite and black tick
Buckinghamshire in England (United Kingdom)
Nike air max Size U.K. 3 used but still in good condition slight mark on white sole Check photo £7
North Yorkshire in England (United Kingdom)
Chanel Red Fingerless gloves
A pair of red Chanel fingerless gloves.100% Cashmere No box no paperNever tried on Never worn.Cash only.
London in England (United Kingdom)
Moncler Coat Mens, Size 3, Great condition, 100% Authentic
Men's Moncler Coat, Size 3 (Fits a small), great condition apart from one of the pocket zips being broken (As shown in pictures). Still have receipt. RRP £675 from flannels. 100% Authentic.
Merseyside in England (United Kingdom)

subset: commoncrawl


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Since 2002 I have been working with people through collaboration, consultation and commission to make improvised quilts from the clothing and materials of everyday life. This practice developed into an active, hands-on, therapeutic process for working through life transitions and bereavement, that I call Passage Quilting. For more information see the Passage Quilting Blog Archive, and Passage Quilting tutorial.
Talking Quilts with Eli Leon ~ Signature Quilt
With its visual field of deep black velvet and twinkling white stitches this African-American signature quilt is as powerful and mysterious as the universe.
Sunny Edwards Memorial Quilt (1918-2011)
Because Rowan's hands chose Sunny's clothes, cut them apart, pieced them back together and participated in the slow process of hand-quilting, the result is not only a memorial to Sunny, but it also embodies the living relationship between them that resides in Rowan's heart.
Sunny Edwards Memorial Quilt ~ Improvisational Patchwork
The improvisational patchwork process mirrors the re-orientation of bereavement.
For Whom The Bell Tolls ~ Remembering Kathreen Ricketson
Through her daily living she translated the importance of slowing down, and rejoicing in the simple pleasures of craft and relationships.
Sunny Edwards Memorial Quilt ~ The Gift of Clothing
Sunny's western shirts, Wrangler chambray and a few Pendleton wools are his gift to his grandson, and the score for our quilt improvisation.
Bereavement Work
I can't imagine the depth and pain of a client's loss, but I can connect with it compassionately when I'm stitching on their quilt.
Good Friday Prayer
It's Good Friday, the day of Christ's death and burial, so I chanted a little prayer to Jesus while I was stitching today.
ready for quilting
The Dolores Wolfe memorial quilt is basted and ready to be quilted. Ruth Anne, Dolores's daughter, will be joining me in June to begin the hand quilting as part of her bereavement process. Ruth Anne also wants to explore adding embellishments of buttons and other mementos from her mother's life, which she will be bringing with her from Cincinnati.
I really like how the quilt top came out. I didn't expect it to look like this but Ruth Anne's mother had such an interesting contrast of fine formal wear, with fitted and fanciful details, and rugged everyday clothing suited to someone who made her life as a farmer and crafts person.
The shapes of Dolores's clothing suggested peaks, and rolling hills, very folksy all in all. I also love the swirling movement of the shapes. Are these mountains or figures dancing? Or as Beth at Smazoochie commented earlier, an old-fashioned family portrait?
a new quilt taking shape
I've been asked to create a memorial quilt for Ruth Anne from the clothing of her mother, Dolores Wolfe. Ruth Anne began this quilt herself in the Passage Quilting™ Workshop that I taught in Cincinnati last fall. She asked me to continue the quilt and finish it for her.
So here are Dolores' clothes. As I began cutting to preserve certain architectural features, a vocabulary of shapes and images began to emerge...
Trees, mountains, peaks, knolls and valleys... Can you see them?
Always at the start of something new, a few simple shapes mysteriously bubble to the surface. The unknown begins to be known in this way.
After two months of moving, and settling I have begun my first quilt in my new studio, in a new spring. I'm wondering about the shapes mysteriously surfacing in my life right now...
A new acceptance of myself, a sense of peace with where I am, renewed attention to my creative life, joy in having my own space to live and grow.
Mini Keepsake Quilt-Along ~ Passage Quilting™ Tutorial ~ Part 1
I am so impressed with all of the comments about ideas and materials for keepsake quilts, by those of you who entered the Whip Up Mini Quilt Book Giveaway. The possibilities are endless.
Choosing Your Materials
If you have gathered your materials and are ready to begin, guess what? You have already completed the first, and one of the most significant steps, of the process. For those of you still on the fence, choose materials and pieces of clothing that resonate most strongly with memory and meaning. These will be the heart of your piece.
- Choose the most resonant materials for the heart of your piece.
- Supplement with less resonant pieces but good colors, texture, pattern, etc.
- Don't limit yourself to woven cotton materials. Anything goes except for leather.
- For a mini quilt try to limit yourself to two or three pieces.
- Beware of too many t-shirt logos.
For the Mini Quilt that I created for Kathreen's book, I asked my friend Liz to provide only two pieces of clothing, one from her son's infancy and one from her pregnancy. These two pieces represented her passage into motherhood, while celebrating the life of her first child.
A mini quilt is a small format so I recommend that you limit yourself to two or three pieces of clothing. Include more pieces if you want to make a larger quilt. The finished size of my mini quilt is only 30" x 24".
Cutting the Clothing Apart
You can always cut your clothing into small squares and create a nine-patch keepsake quilt. However, Passage Quilting™ is about the process of transition, growth and healing. For this reason I work with the architecture of the clothing to create an improvised quilt without a predetermined pattern.
- As you begin to cut your clothing apart consider which architectural features you want to include in your quilt and cut accordingly.
- Cut the clothes along seam lines.
- Remove extra linings and bulky seams.
- Prep, cut apart, all of your materials before moving to the piecework.
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Next Monday, in Part 2 of the Keepsake Quilt-Along, we will begin making blocks or sections from our clothing parts. I will also review tips on improvisation and curve piecing techniques.
What was it like to cut apart your meaningful materials? Was it liberating? Scary? Sad? Joyous? A relief? A surprise? A mixture of emotions? Please share!
Walter F. Kenney, Jr., February 2011
Walter F. Kenney, Jr. 2011, 54" x 48", machine and hand-pieced, hand-quilted, from the clothing of Walter F. Kenney, Jr.
Lauren Kenney asked me to make a memorial quilt out of her father's clothes as a gift for her mother. Lauren and her husband came to my studio with a few choice items of clothing, a gold coat beloved by her father in spite of her mother's sense of better taste, golf club covers, gloves, and towel, a favorite plaid shirt, old jean shorts and a pair of suspenders.
Walter was a down to earth kind of guy who used a rope as a belt when working out in the yard. He served in the U.S. Marine Corps, and as a Connecticut state police officer, and was a loyal Red Sox fan. By his clothes, I can see that Walter had a colorful and bold personality!
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This quilt took 19 hours to complete. If you are interested in having a memorial or bereavement quilt made contact me or for more information visit Passage Quilting
Passage Quilting™ Bereavement Workshop in Cincinnati
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In December I was invited to lead a bereavement, memorial quilt making workshop in Cincinnati. Six people attended, each with the loss of a child, parent, or close friend. Everyone brought clothing of the person they were mourning to use as the material for their quilts.
We began the two day workshop sitting around an alter we made of photographs of the ones we loved and lost. Each person brought one piece of clothing to the alter and shared the story that it contained. Soon we were cutting up the wedding dresses, the jeans, the soft baby toys, the nightgowns, and the work shirts of our beloved.
After lunch the reconstruction began. We didn't have pre-determined patterns to follow. Each person worked intuitively and with the architecture of the clothing to reorder the fragments into new patterns and transformed relationships.
The next day we sat around the alter again and shared the many insights that came up overnight because of the process. People brought relief, fear, anger, sadness, gratitude, compassion, love, and forgiveness to the table. No one's feeling or experience was left out. The group was able to hold everyone's different expressions of grief.
We followed this time of sharing with another full day of cutting and sewing. We learned new patchwork and improvisational skills. We learned how to piece organically without rulers, how to sew knits, hand stitch delicate elements of clothing, and how to pull it all together into a composition. From my perspective it was an abundant time, full of sorrow, joy, friendship, and healing.
If you are interested in finding out more: Passage Quilting™ is a hands-on bereavement process that I developed and began facilitating in the fall of 2001.
Veteran's Day Virtual Sewing Circle
Even though the war in Iraq is supposedly over, deadly emotional ramifications continue to persist. Join me for a virtual sewing circle in honor of Veteran's Day. Help stitch the names of soldiers who have died in the Iraq war as a meditative act of petition, prayer and compassion.
Making Memorial Quilts from the Clothing of the Beloved
Announcing a Passage Quilting Workshop in Cincinnati, OH. This is a hands-on bereavement process, making memorial quilts from the clothing of the beloved.


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Study In China
China is one of the fastest developing countries in the world and become popular due to its great career building opportunities by offering different degree programs in Bachelors, Masters and PHD for international students from all over the world. China offers authoritative, comprehensive and instructive education in wide fields of Business, Medical, Engineering, Arts, Sciences and many more which has an immense effect on her literacy rate. Not only local education, international education in china has boomed also in past few years. According to survey more than 439875 international students came to study abroad in China. Due to this trend and great level of education everyone wants to know about how to study in China for international students. So if you are searching for study in China for Pakistani students then you are at right place. EUCAN International Education Immigration Consultants have a wide experience of more than 8 years in providing best consulting services to study in china from Pakistan.
EUCAN International Education Immigration Consultants is providing services to study in china in English in all degree levels like Bachelors, Masters and PHD in well known universities. EUCAN International Education Immigration Consultants have contract with top ranked and well known universities of china.
- Formal name: Peoples Republic of China (PRC)
- Capital: Beijing
- Area: 9,600,000 sq km
- Population: 1.3 billion (as of 2004)
- Language: Mandarin Chinese (Putonghua) based on Beijing dialect, plus local dialects
- Climate: Extremely diverse; tropical in the south to subarctic in the north
- Currency and Monetary Unit : Renminbi/Yuan
- Form of Government: system of National Peoples Congress
- Administrative Demarcations: 23 provinces, 5 autonomous regions, 4 municipalities, and 2 Special Administrative Regions
- World's second largest and fastest growing economy
- Quality of Education and International Recognition
- Experience the great Chinese Culture First-hand
- Gain proficiency in Chinese language
- Great acceptability while approaching employers
- Great opportunity to work there on completion of your programme
- Affordability
- Travel and Exploration opportunities
Higher Education system of china consist of Junior college, undergraduates and postgraduates.
- junior colleges schooling -2-3 years duration
- Universities 4 years, except medical courses which need five years for graduation.
- Postgraduate study 3 years
- Doctoral Degrees 3 years.
- TOEFL or IELTS. (Entry requirements varies from universities to universities)


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Shelly skirt is that dramatic voluptuous full-bodied skirt your collection is been missing. We love it with a bodice top for that glam occasion. By I Am Woman.
Shelly is available in one size. It is very elastic fitting most body types.
Poly/cotton blend.
Cold hand wash is recommended.
|Waist cm
|Length cm
|One size


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Baikal Blue Marble Material
Baikal Blue, latest hot-seller, is a trendsetting material featuring background without any veining. With classic look, it will perfectly match with different styles, whether decorated as floor or wall coverings. Its striking characters allow it to be an ideal material to add redefined elegance and luxury.


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Winter is truly a magical time of year. There are twinkling Christmas lights strung up on every street, fluffy snowflakes falling from the sky, and tons of fun outdoor activities to take part in! There's honestly no reason to be bored during the wintertime and especially not during the holidays when there are so many adorable, romantic adventures to go on.
One of the most romantic and wintry adventures that every Canadian should experience once in their life is a horse-drawn sleigh ride through a literal winter wonderland! At Back Of Beyond Equine Centre, you can go on a romantic ride all year round.
READ ALSO: You Can Rent These Adorable Mini Cabins Across Ontario For A Magical Night In The Forest
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Back of Beyond Equine Centre is located in the gorgeous cottage country of Muskoka, Ontario which is just a short 2.5-hour drive from Toronto. They have adorable sleigh-rides running all year-long but their winter rides are clearly the most scenic!
The adventure starts with a tour of the farm and the opportunity to brush the horses before the ride begins. Then the magical ride through private woodland trails begins where you'll get to experience a real-life winter wonderland through the most romantic modes of transportation!
READ ALSO: This 2.3 KM Winter Trail Will Lead You Past Caves And Stone Bridges Near Toronto
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They have 3 different sized sleighs to choose from, a small sleigh that fits 4 people, a family sleigh that fits 7 people, and a larger sleigh that fits 12 people. They'll take you through the snow-covered trails and then once you're done you can enjoy a warm hot chocolate on the farm!
It costs $125 for 2 people and then any additional person that is added costs $25 each. Children under 4 ride for free though! The sleigh rides are weather dependent and are decided by the farm-owners on a day-to-day basis so make sure you check the weather before you book.
Check out their website for more information and to book your sleigh ride online!


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Innovate or Stagnate!
in Monthly Newsletter
04 Feb 2014
A consistent mantra over the last few years has been "strive to do more, with less." Yet full-time employees in the UK work longer hours than the European Union average, but are 16% less productive, according to data from the Office for National Statistics for 2012. The 2013 figures are expected to be worse!
"Work smarter, not harder" is another phrase that many people quote but few seem to effectively put into practice. Obviously, there are exceptions and these seem to be the businesses that are developing despite the recession. So what are their secrets?
The first is that these businesses have a very clear understanding not only of what they want to achieve and how to achieve it, but also an understanding of why they want to achieve it and the values within which they want to operate. They then make sure that their business is fit for purpose.
The second secret is that they are prepared to innovate, which simply means finding new and better ways of doing things that will enable people to work more effectively without
necessarily working harder or longer. Whilst we have never met anyone who openly says that they would not like to be able to reduce their work load by working smarter, we have come across many who do their best to block change by appearing to present well considered objections.
Although many staff believe that they are already working as hard, fast and as long as they can, improving staff performance remains the key to improving overall performance.
Unfortunately, as the 12 things that people say to kill good ideas clearly shows, most people dislike change but love skuamorphs. (A skuamorph is a practice which continues to exist even though the reasons for it coming into practice have long since ceased to exist).
An effective innovation strategy is about much more than having suggestion boxes, even though these do produce some good ideas. As many of the most innovative organisations around demonstrate, in order to achieve the most significant returns it is necessary to appoint someone with specific responsibility for innovation, set targets to be achieved and provide appropriate resources. The project must then have direct and continuing support of the senior management team in order to ensure that it is seen as a significant and high profile project and one with which managers of all levels need to both cooperate and be seen to be cooperating.
An important factor for success is the need to gain genuine staff support. Experience has shown that where staff can personally present their ideas to an Innovation Manager, the number and quality of the ideas put forward rises significantly. Equally important is the need to ensure that everyone who submits an idea is kept fully informed of how their suggestion is being progressed and of the final outcome.
Finally it is vital to give appropriate recognition to all who submit ideas, ensuring that innovation is seen to be the key to improving performance.


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A great option as an alternative to coffee in the morning or a nourishing sweet tea for the 4pm slump...Read More
This is a go to recipe in the ROOTED KITCHEN. Using simple and easy ingredients it's fool-proof too and so quick to do, you can do it mid week too. Pancakes made easy!Read More
The king of the banana bread, the ROOTED recipe is gluten and refined sugar free...a serious taste sensation for breakfast, afternoon tea, snacking or just when you need a nourishing treat...Read More


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Symple Stuff Pettitt Etagere Bookcase
Special Price
$43.99 (This is not last updated price)
Symple Stuff Pettitt Etagere Bookcase Description
Simple and stylish, this etagere bookcase brings Scandinavian appeal to any space. Crafted of imported solid pine wood in a natural finish to show off its unique character and wood grain, this petite bookcase strikes an open rectangular silhouette with four legs and an X-frame back measuring 26.97" H x 23.6" W x 11.6" D overall. Two slatted shelves provide perfect platforms for displaying rows of your favorite reads, collected curios, and other multimedia, while the slatted top offers even more... Frame Material Details: Pine Shelf Material: Wood Assembly Required: Yes Overall Product Weight: 8.8lb.
Why do people buy the Symple Stuff Pettitt Etagere Bookcase?
The Holiday's Sale is coming soon, but some bookcase already have good sale prices. I have to do this review. This is a great furniture for this price. If you want a trendy furniture this one is not for you! How anyone could complain about this furniture for the price is beyond me.
This is a furniture
The Symple Stuff Pettitt Etagere Bookcase Reviews
Definitely my favorite brand of bookcase(s). But when I saw this bookcase at street shop for , I said, I don't think so..., then drove home to look for them on where else? Online Shop! For Lowest price. Pleased as ever with these. all a great price. Buy new furniture, No crowds! The best reason to shop online by far. who wants to scrum their way through a crowded store? Set up your laptop and sit with a shortbread biscuit and mug of tea. Bliss. Do You Know Big Holiday Sale is coming soon, Happy with Shopping Together.
Symple Stuff Pettitt Etagere Bookcase
Symple Stuff Pettitt Etagere Bookcase Symple Stuff Pettitt Etagere Bookcase
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Customer Reviews
I am glad I bought this bookcase. I'm looking forward to wearing it to work and social occasions. And of course, I love the bookcase! A well designed feature that doesn't add bulk. 2 words : perfect bookcase.
This is the best thing I've ever worn! I bought it during the anniversary sale and plan on buying another one. I've worn it every day since it arrived. Everyone should own one! Shipping was FAST as well. It came in 2 days with regular shipping.
I purchased the this product and it was just what I was looking for. Can't beat the price on this this product. I got the this product and it looks great. This this product is PERFECT for me! I'm considering getting another color.


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During our last 3 sessions, we have built graphql servers using javascript and for this session we will have a guest Seth Kigen who will take us through what it takes to build a graphql server in python.
We will be working off from this repo https://github.com/nairobi-graphql-meetup/graphql-python-example so bring your laptop and let's GraphQL!
Hope to see you there.


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#2 HD Stand-Up™
The #2 HD Stand-Up™ bag is constructed of high-density polyethylene, offering a more stiff and robust packaging for fresh produce to stand upright on the shelf.
This light-weight packaging is comparable to polypropylene in stiffness, offering the same rigid feel, while significantly reducing waste, energy use, and global warming potential than alternatives. Recycle Code #2
#4 Fox Eco Stand-Up™
The #4 Fox Eco Stand-up™ bag adopts the convenience of the stand-up format and features an eco-starch resin, offering a reduction in plastic consumption. This biopolymer is both sustainable and durable, preserving the integrity of the packaging design.
This low-density polyethylene highlights the value of produce without compromising our ecosystem. Recycle Code #4
Fox Stand-Up Combo®
Constructed of both poly and mesh materials for a functional yet visually appealing product presentation, the patented Stand-up Combo® Bag features a convenient, flat bottom for upright display.
The breathable mesh material is available in 10 product enhancing colors and comes with a zip closure. Recycle Code #4
Weight Range
Ideal for single and small portion pack sizes
Mesh Colors
More than 10 colors of non-abrasive mesh
Printing Process
Solvent based surface flexo printing produces a high dynamic range of colors
High graphic poly-front


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Wheeling Park's Trevor Thomas Earns Class AAA First Team All-State Baseball Selection
Patriots' Shia, JM catcher McCool are second team
It's been quite a ride for the 12 seniors on the Wheeling Park baseball team.
They've been a part of three teams to reach the state tournament and made an appearance in the 2018 state championship.
The Patriots made another remarkable run at it this year led by senior Trevor Thomas.
The shortstop known as "Tubes" batted .386 with 34 hits, 10 doubles, 20 RBI and 27 runs.
He accumulated an on-base percentage of .472 and turned in four saves in relief.
Those numbers combined with his leadership has earned him first team all-state in Class AAA for the second consecutive year, as selected by the West Virginia Sports Writers Association.
His senior teammate and middle infield partner, Jacob Shia, picked up second-team honors.
Together, the duo of Shia and Thomas turned 14 doubles plays this year.
Shia supplied a .375 average with 31 hits, eight doubles, 32 runs and 21 walks at the leadoff spot with an on-base percentage of .528.
There weren't many catchers in the state that had a better season than John Marshall's Chas McCool.
Along with being a defensive weapon behind the dish for coach Mark Cisar, he hit at a .463 clip and blasted 50 hits, 12 doubles, four triples and two home runs.
He knocked in 32 RBI with 22 runs, eight walks and swiped 14 bases in the process.
Three of the state's brightest baseball stars used the grandest of stages in West Virginia to demonstrate why they are Class AAA All-Staters as well as future NCAA-Division I players.
Jonathan Blackwell, Jake Carr and Chase DeLauter all shined brightly during last weekend's state tournament.
Each turned in sterling performances for their respective teams at Appalachian Power Park.
Carr pitched a three-hitter for eventual state champion St. Albans in a (5-1) victory over Wheeling Park in one semifinal, while Blackwell of Hurricane and DeLauter of Hedgesville waged one the best pitching duels the state has seen in a 1-0 victory by Blackwell in the other. Both pitchers tossed two-hitters with one walk in that semifinal.
Additionally, DeLauter reached base two of three times Blackwell allowed someone on, doubling and walking.
DeLauter's offensive prowess to go with his pitching ability are a reflection as to why he signed on as a two-position player — a pitcher and an outfielder — at James Madison.
Blackwell and Carr are headed to Coastal Carolina and West Virginia, respectively, as strictly pitchers.
Today, two of them — Carr and DeLauter — head up the Class AAA all-state team as co-captains of the first team.
Beside being repeat first-team selections as a pitcher and utility player, respectively, Carr and DeLauter have been named as co-state players of the year. Blackwell moved up from the second team in 2018.
It's the second straight time for DeLauter to win the John Lowery Award as the state's top player. He certainly did everything in his power to keep the trophy as he raised his batting average by slightly more than 100 points to .606 and lowered his earned run average by more than a run to 0.84.
Carr finished won all seven of his decisions and posted an 0.33 ERA while striking out 105 and walking just 14 in 63 innings.
Seven of the 15 first-team honorees hail from the Mountain State Athletic Conference, including all three pitchers, and five from the six-member Eastern Panhandle Athletic Conference.
In addition to Carr and Blackwell, the third pitcher is Cody Sharp of MSAC member Spring Valley.
The other MSAC honorees are infielder Joel Gardner, who scored the lone run in Hurricane's win over Hedgesville in Charleston, and George Washington's Aidan Johnson; outfielder Easton Petitt of Cabell Midland; and utility player Tyler Cox of Hurricane.
Besides DeLauter, the EPAC first-teamers also include infielder Grant Harman from Martinsburg, outfielders Hunter Coe of Hedgesville and Blake Hartman of Musselman, and utlity player Taylor Tennat of Jefferson.
The rest of the first-team lineup includes catcher Tyler Haskins of Ripley and utility player Hunter Fansler of Woodrow Wilson.
The second team is led by Noah Cummings, an infielder from state champion St. Albans who was a first-team honoree a year ago and has been named the captain.
The pitchers include Cabell Midland's Chad Heiner, Parkersburg South's Colin Bryant and Ayden Hodges, who tossed a one-hitter in St. Alabans' 5-0 victory over Hurricane in the state championship game.
Nick Loftis of St. Albans earned second-team honors as a utility player a season ago but was named as an infielder this time.
The rest of the second team includes catcher infielder Hunter Bellomy of Spring Valley; outfielders Andrew Sydenstricker of Capital, Dane Peterson of Ripley and Charlie Pierson of Riverside; utility players Ashton Staubs of Martinsburg, Caleb Taylor of Morgantown, Blake Tilley of Cabell Midland and Cam Thomas of Capital.


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Who plays jorge in meet the fockers
Meet the Fockers - Wikipedia
Baby Jack provided us with all the LOLs in the Meet The Fockers. The adorable tot was played by Spencer and Bradley Pickren. The boys haven't Ray Santiago AKA Jorge Villalobos[Twitter/Universal]. Unbelievably, Ray is. Meet the Fockers Theatrical release poster Directed by Jay Roach At the engagement party, Jack introduces Greg to Jorge, and later when. In Meet the Parents, Jack pulled CIA rank to free Greg after he yelled "Bomb, Bomb, Bomb! To make Ray Santiago (Jorge) look like Ben Stiller, they gave him blue Dustin Hoffman wanted to play Greg's dad ever since the character was.
Her father was a school teacher at the same school. Streisands family was Jewish, her grandparents emigrated from Galicia and her maternal grandparents from the Russian Empire. Her father earned a degree from City College of New York in and was considered athletic. As a student, he spent his summers outdoors, once working as a lifeguard, hed try anything, his sister Molly said.
He married Ida intwo years after graduating, and became a respected educator with a focus on helping underprivileged.
In Augusta few months after Streisands first birthday, her father died suddenly at age 34 from complications from an epileptic seizure, the family fell into near-poverty, with her mother working as a low-paid bookkeeper.
As an adult, Streisand remembered those early years as always feeling like an outcast, explaining and her mother tried to pay their bills but could not give her daughter the attention she craved, When I wanted love from my mother, she gave me food, Streisand says.
Streisand recalls that her mother had a voice and sang semi-professionally on occasion. During a visit to the Catskills when Streisand was thirteen, she told Rosie ODonnell, she and that session was the first time Streisand ever asserted herself as an artist, which also became her first moment of inspiration as an artist. She has a brother, Sheldon, and a half-sister 5. Cochrane, one story has Laemmle watching a box office for hours, counting patrons and calculating the days takings.
Within weeks of his Chicago trip, Laemmle gave up dry goods to buy the first several nickelodeons, for Laemmle and other such entrepreneurs, the creation in of the Edison-backed Motion Picture Trust meant that exhibitors were expected to pay fees for Trust-produced films they showed. Soon, Laemmle and other disgruntled nickelodeon owners decided to avoid paying Edison by producing their own pictures, in JuneLaemmle started the Yankee Film Company with partners Abe Stern and Julius Stern.
Laemmle broke with Edisons custom of refusing to give billing and screen credits to performers, by naming the movie stars, he attracted many of the leading players of the time, contributing to the creation of the star system. Laemmle, who emerged as president in Julywas the figure in the partnership with Dintenfass, Baumann, Kessel, Powers, Swanson, Horsley. Eventually all would be out by Laemmle. Following the westward trend of the industry, by the end of the company was focusing its efforts in the Hollywood area.
On March 15, Laemmle opened the worlds largest motion picture production facility, Universal City Studios, studio management became the third facet of Universals operations, with the studio incorporated as a distinct subsidiary organization. Unlike other movie moguls, Laemmle opened his studio to tourists, Universal became the largest studio in Hollywood, and remained so for a decade. However, it sought an audience mostly in towns, producing mostly inexpensive melodramas, westerns. In its early years Universal released three brands of feature films — Red Feather, low-budget programmers, Bluebird, more ambitious productions, and Jewel, their prestige motion pictures.
Leonard, George Marshall and Lois Weber, despite Laemmles role as an innovator, he was an extremely cautious studio chief. Unlike rivals Adolph Zukor, William Fox, and Marcus Loew and he also financed all of his own films, refusing to take on debt. Character actor Lon Chaney became a card for Universal in the s 6.
Starring Robert De Niro and Ben Stiller, the film chronicles a series of events that befall a good-hearted. Glienna—who also played the films main protagonist—and Mary Ruth Clarke co-wrote the screenplay.
Universal Studios purchased the rights to Gliennas film with the intent of creating a new version, Jim Herzfeld expanded the original script but development was halted for some time.
Jay Roach read the script and expressed his desire to direct the film. At that time, Steven Spielberg was interested in directing the film while Jim Carrey was interested in playing the lead role, the studio only offered the film to Roach once Spielberg and Carrey left the project.
Meet the Parents was well received by critics and viewers alike, winning several awards. The success of Meet the Parents inspired two sequels, namely Meet the Fockers and Little Fockers released in and respectively.
Meet the Parents also inspired a reality show titled Meet My Folks. Gaylord Greg Focker is a living in Chicago. He intends to propose to his girlfriend Pam Byrnes, but his plan is disrupted when he learns that Pams sisters fiance had asked Pams father for permission before proposing, Greg and Pam travel to Pams parents house to attend Pams sisters wedding. Greg hopes to propose to Pam in front of her family after receiving her fathers permission, but this plan is put on hold when the airline loses his luggage, including the engagement ring.
At the Byrnes home, Greg meets Pams overbearing father Jack, mother Dina, Jack takes an instant dislike to Greg and openly criticizes him for his choice of career as a male nurse and whatever else he sees as a difference between Greg and the Byrnes family. Greg tries to impress Jack, but his efforts fail, Greg becomes even more uncomfortable after he receives an impromptu lie detector test from Jack and later learns from Pam that her father is a retired CIA counterintelligence officer.
Meeting the rest of Pams family and friends, Greg still feels like an outsider and he also feels inferior to Kevin, Pams ex-fiance who, unlike him, receives nothing but warmth and friendliness from Jack 7. The hamlets area was larger before several of its parts incorporated as separate villages. The English, under Peter Wright, first settled in the area inthe boundary between the Dutch and English was somewhat fluid which led to each group having their own Main Street. For a six-month period from tothe Townsend home served as British headquarters for the Queens Rangers led by Lt.
The plot was thwarted when three Americans on patrol captured Andre near West Point, preventing what would have been a defeat for the colonists in the Revolutionary War.
In the following year, service commenced with the coaches being loaded onto a ferry for a connection to the New Haven Railroad at Norwalk. Service lasted less than a year, Sagamore Hill was completed in This is where Roosevelt lived until his death in and his wife Edith Roosevelt continued to occupy the house until her death, nearly three decades later, in September These include design of the Theodore Roosevelt Memorial Park and this beautiful waterfront park gives residents and visitors alike access to the pristine and beautiful Oyster Bay Harbor 8.
New York state — New York is a state in the northeastern United States, and is the 27th-most extensive, fourth-most populous, and seventh-most densely populated U. With an estimated population of 8. Both the state and New York City were named for the 17th-century Duke of York, the next four most populous cities in the state are Buffalo, Rochester, Yonkers, and Syracuse, while the state capital is Albany.
New York has a diverse geography and these more mountainous regions are bisected by two major river valleys—the north-south Hudson River Valley and the east-west Mohawk River Valley, which forms the core of the Erie Canal. The central part of the state is dominated by the Finger Lakes, New York had been inhabited by tribes of Algonquian and Iroquoian-speaking Native Americans for several hundred years by the time the earliest Europeans came to New York.
The first Europeans to arrive were French colonists and Jesuit missionaries who arrived southward from settlements at Montreal for trade, the British annexed the colony from the Dutch in The borders of the British colony, the Province of New York, were similar to those of the present-day state, New York is home to the Statue of Liberty, a symbol of the United States and its ideals of freedom, democracy, and opportunity.
In the 21st century, New York has emerged as a node of creativity and entrepreneurship, social tolerance. Verrazzano described it as a vast coastline with a delta in which every kind of ship could pass and he adds.
This vast sheet of water swarmed with native boats and he landed on the tip of Manhattan and possibly on the furthest point of Long Island. Verrazannos stay was interrupted by a storm which pushed him north towards Marthas Vineyard, in French traders from New France built a chateau on Castle Island, within present-day Albany, due to flooding, it was abandoned the next year. Inthe Dutch under the command of Hendrick Corstiaensen, rebuilt the French chateau, Fort Nassau was the first Dutch settlement in North America, and was located along the Hudson River, also within present-day Albany.
Blogs - Story Notes for Meet the Fockers - AMC
The small fort served as a trading post and warehouse, located on the Hudson River flood plain, the rudimentary fort was washed away by flooding inand abandoned for good after Fort Orange was built nearby in Henry Hudsons voyage marked the beginning of European involvement with the area, sailing for the Dutch East India Company and looking for a passage to Asia, he entered the Upper New York Bay on September 11 of that year 9.
Miami — Miami is a seaport city at the southeastern corner of the U. According to the U.
Census Bureau, Miamis metro area is the eighth-most populous, Miami is a major center, and a leader in finance, commerce, culture, media, entertainment, the arts, and international trade. It ranked 33rd among global cities, inForbes magazine ranked Miami Americas Cleanest City, for its year-round good air quality, vast green spaces, clean drinking water, clean streets, and citywide recycling programs.
Miami has the third tallest skyline in the U. The Civic Center is a center for hospitals, research institutes, medical centers. For more than two decades, the Port of Miami, known as the Cruise Capital of the World, has been the number one cruise port in the world. It accommodates some of the worlds largest cruise ships and operations, Metropolitan Miami is the major tourism hub in the American South, number two in the U.
The Miami area was inhabited for thousands of years by indigenous Native American tribes, the Tequestas occupied the area for a thousand years before encountering Europeans. An Indian village of hundreds of people dating to — B. A Spanish mission was constructed one year later inSpain and Great Britain successively controlled Florida, and Spain ceded it to the United States in Inthe US built Fort Dallas as part of its development of the Florida Territory and attempt to suppress, the Miami area subsequently became a site of fighting during the Second Seminole War.
Miami is noted as the major city in the United States conceived by a woman, Julia Tuttle, a local citrus grower. The Miami area was known as Biscayne Bay Country in the early years of its growth. In the late 19th century, reports described the area as a promising wilderness, the area was also characterized as one of the finest building sites in Florida.
The Great Freeze of —95 hastened Miamis growth, as the crops of the Miami area were the ones in Florida that survived. Recreational vehicle — A recreational vehicle is, in North America, the usual term for a motor vehicle or trailer equipped with living space and amenities found in a home. A recreational vehicle includes a kitchen, a bathroom. Less commonly found features are a hot tub, a room, a desk.
Most RVs are single-deck, however, double-deck RVs also exist, RVs are defined as either motor vehicles or towable trailers, and are primarily intended for leisure activities such as camping and vacations. They are usually found in RV parks or campgrounds, and can be rented in most major cities, other RVs serve as traveling permanent homes. People who use their RVs as traveling permanent homes on a full-time basis are commonly referred to as full-timers, recreational vehicle types include the motorhome, travel trailer, fifth wheel trailer, toy hauler, popup trailer, and slide-in camper.
See also the list of recreational vehicles, Most modern dictionaries give one of the meanings for the word caravan as a camper equipped with living quarters. They had been friends their whole lives, but this was their first movie together. In the late s, when Hoffman first became famous, an unknown De Niro waited on him at a restaurant. Teri Polo had her first child injust before filming this. Alanna Ubach is playing the older woman, but she is ten years younger than Ben Stiller in real life.
Stiller joked that the worst thing his famous parents did to him was go on game shows and lose. Streisand also directed it. Director Jay Roach actually used the Ferber method on his 1st child. Almost everyone who saw the movie knew that Dustin Hoffman and Barbra Streisand were coming up. Since it was going to be a while before they appeared, Jay Roach wanted to give the audience a preview.
Teri Polo is back as Pam. This was just a year before she started on The West Wing Robert De Niro had a behind the scenes role as a producer on both Parents and Fockers. Their mother, a pediatric nurse, taught them how to sign. Stiller called her and told her that she should do it. She was so impressed she said yes. Alanna Ubach plays Isabel Villalobos. She was in both Legally Blonde movies. Legendary comic Shelley Berman plays Judge Ira. It just makes you feel drunk. Historical Note Capoeira, created by slaves in Brazil, was disguised to look like a game to fool slave owners.
Location Notes Only one part of the movie was filmed in Miami. Everything else was shot in Los Angeles. Some shoot locations include the L. Arboretum and Botanic Garden.
Other songs played in the film include: Bush was re-elected in Playboy thought Teri Polo was hot. Jack shares the middle name Tiberius with Captain Kirk. Ben Stiller is a huge Star Trek fan. Parents was so successful that plans for Fockers began while the first movie was still in theaters.
Meet the Fockers and Little Fockers: Where are they now?
Jinx is a Himalayan cat. All but one of the cats who play him are from rescue shelters. Stiller said they never considered casting his real parents, comedy duo Jerry Stiller and Anne Meara. Still, she was heavily involved, from developing the script to choosing her makeup and wardrobe.
The studio ran a contest where people named Focker could win a trip to their Universal Studios theme park. There were almost no Fockers in America.


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The summer solstice marks the longest day of the year and the official start of summer.
Join us on the garden patio as we celebrate the sun and coming season, one of abundance and light. Dress up in your most floral finery and enjoy a menu of refreshing tea-based drinks and multiple courses of savories and sweets.
We're also including Tea 101 and tasting classes throughout the evening. Entry includes 2 drink tickets.
Tea Tasting + 101 classes
Friday June 14 at 7pm
Come and explore the world of tea with Ari, our in-house tea consultant!
This class will be a basic 101 class that will inform you on many tips and tricks to brew the perfect cup! While sipping on a variety of teas, there will also be savory bites to cleanse the palate!


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I spend a lot of time talking about food. And while it's true that I enjoy a good meal and a glass of wine…it's typically dog (or kitty) kibble in the context of a veterinary visit that I am talking about.
Those who've stumbled on this blog before (n = blood relations), have read my mention of definitions and how these can vary markedly between individuals. As another example of this, the word 'diet' is defined by most of us who practise clinical nutrition as everything the dog or cat in question consumes in a typical week. In addition to the bulk of the diet (usually kibble), this encompasses treats, supplements, snacks and whatever other 'little something' he or she might get from his/her owner, the floor, grandma, etc. However, the word 'diet' can mean something rather different to the average pet-owner when asked, 'what does your pet eat?' and due to my disinterest in quibbling (and desire for brevity) I'll leave the variations of responses to your imagination. To try to get everyone on the same nutritional page, and because I try to teach my students how to be efficient and consistent (aka I'm a slacker and compensating for poor detail-oriented task skills), I typically advise obtaining pet diet information via a nutrition history-questionnaire.
Here's an example of a standardized diet history questionnaire: http://www.wsava.org/WSAVA/media/Arpita-and-Emma-editorial/Diet-History-Form.pdf
These types of questionnaires let me know what the pet is eating (the whole diet) and their activity level. The rest of the pet's nutritional assessment (weight, body and muscle condition score), other history and physical exam helps me figure out how they are doing with their current diet/exercise. Putting all that info together allows us (vets) to provide recommendations for ongoing care... However, the first step in any type of planning is obtaining information, and that (i.e. pet specific nutrition information) can vary dependent on where you practise and who is coming to your veterinary clinic.
Here's a piece of recently presented research that surveyed clients coming into the Atlantic Veterinary College small animal veterinary teaching hospital, with some interesting results from a nutrition, exercise and infection control standpoint:
Nutritional Knowledge, Attitudes, Perceptions and Practices of Clients Presenting to a Small Animal Veterinary Teaching Hospital , VSRA Texas 2018
M. Peace, J. Stull, G. Munguia, and M. Evason
1)Determine teaching hospital small animal clientele current knowledge, attitudes, perceptions and practices regarding nutrition and exercise
2) Evaluate client recall on veterinary recommendations related to diet and exercise
Sample of clients visiting the small animal Atlantic Veterinary College Teaching Hospital from June 8th to July 4th, 2018 were invited to complete a paper questionnaire. Descriptive statistics were used to evaluate questionnaire data.
Total of 143 clients were invited to participate- 140 agreed to participate, with 106 pet-owners returning the questionnaire.
Surveys that were <50% completed were excluded, providing a 71% response rate (n=101).
This is wonderfully high level of interest, cooperation and response.
A variety of responses were recorded in response to 'What does your pet's diet consist of in a typical week?' The majority of responses to this question were similar to other studies of this nature; however, total raw food intake (commercial, homemade, treats) was 30%. This result is higher than other studies of this type and VERY important information for hospital infection control planning and prevention of disease transmission (e.g. salmonella) to other pets and staff.
Pet-owner interest in learning more about their pet's nutrition was reported as:
▪Yes-very interested (63%), No- not interested (22%), Unsure (15%)
As in other studies, pet-owner interest in the topic of nutrition and diet for their pet is high.
Pet-owner recollection of discussing nutrition with vet:
▪Always speak about nutrition (35%)
▪Sometimes speak about nutrition (44%)
▪Unsure (19%), never (3%)
Again, similar to other studies while pet-owners indicate a desire to speak about nutrition this isn't something that appears to be occurring regularly during visits to the vet clinic, i.e. over 20% of the time it isn't happening, and it's hit or miss about half the time.
Pet-owners varied in their interest in having their veterinarian discuss their pet's exercise requirements. Responses to this query were as follows: somewhat agree that I'd like my vet to talk about my pet's exercise needs (36%), strongly agree and want vet to discuss (27%), felt neutral about having this discussion(26%), strongly disagree and do not want to talk about exercise for pet (8%), somewhat disagree (3%).
This was an interesting result and worth exploring further to assess differences between cat vs. dog owners, and whether things differed between reported exercise (amount, frequency) and interest in exercise related discussions.


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Sandow organized the first bodybuilding contest on September 14, 1901, called the "Great Competition". It was held at the Royal Albert Hall in London. Judged by Sandow, Sir Charles Lawes, and Sir Arthur Conan Doyle, the contest was a great success and many bodybuilding enthusiasts were turned away due to the overwhelming amount of audience members.[4] The trophy presented to the winner was a gold statue of Sandow sculpted by Frederick Pomeroy. The winner was William L. Murray of Nottingham. The silver Sandow trophy was presented to second-place winner D. Cooper. The bronze Sandow trophy — now the most famous of all — was presented to third-place winner A.C. Smythe. In 1950, this same bronze trophy was presented to Steve Reeves for winning the inaugural NABBA Mr. Universe contest. It would not resurface again until 1977 when the winner of the IFBB Mr. Olympia contest, Frank Zane, was presented with a replica of the bronze trophy. Since then, Mr. Olympia winners have been consistently awarded a replica of the bronze Sandow.
As a parting thought, we can't emphasize enough the importance of consistency and staying focused. Your workouts shouldn't be two-hour affairs—each visit to the gym needs to be fast-paced and intense. With that as your guide and following the heavy-duty blueprint laid out here, we can't promise it'll be easy, but the results should be worth every drop of sweat. Just think, 10 more muscular pounds may be a mere month away.
As stated before, one of the primary hip flexor muscles is the psoas major. This muscle plays a role in core stabilization (something that is needed during running, squatting, and sitting) due to its attachment site at the spine. If there is a lack of core stability or poor movement patterns during these tasks then the hip flexor can become overworked/tired/fatigued (think what happens when your co workers or teammates don't do their job, you have to pick up the slack and work harder, bringing you more stress and fatigue). It is when the hip flexor becomes fatigued that the sensation of tightness sets in. This is because the hip flexor has to "work harder" to compensate for other muscles not doing their job.
Those micro-tears that are such a key factor for muscle-building need rest to rebuild themselves and grow stronger. When do they do that? When you're asleep! "You have to rest and feed your muscles between workouts or you will tear them down and they will become weaker," says Olson. "Over time, you run the risk of over-training, which can result in injury, and possibly even more sleep troubles."
To test the flexibility of the hip flexors, specifically the iliopsoas, the Thomas' test10 is used. The patient lies supine and flexes one hip, pulling one knee to the chest. If a hip flexion contracture is present, the contralateral straight leg will rise off of the table. The modified Thomas' test (Figure 12.11) may be preferred. With this variation, the patient sits at the end of the examination table with the knees flexed to 90 degrees. Next, one knee is pulled tight to the chest. The patient is instructed to lie down while maintaining the knee against the chest. If a hip flexion contracture is present, the contralateral leg will rise off of the table. If a rectus femoris contracture is present, the contralateral knee will extend.
According to research from the University of Stirling, for optimal protein growth, weight lifters need to eat 0.25 to 0.30 grams of protein per kilogram body weight per meal. For a 175-pound person, that works out to 20 to 24 grams of protein at every meal. You'll get that in three to four eggs, a cup of Greek yogurt, or one scoop of protein powder.
Low Carb is for everyone. This has to do with carbs. If someone has high body fat percent, this is because the fat from meals whether is from fats or carbs spilling over…is staying stored causing a calorie surplus. The body only needs a certain amount of energy (food). People with high body fat usually over feed on carbs because carbs are everywhere, which makes it safe to assume they are always storing sugar as fat and signaling insulin. This plus, the insulin response due to the surplus causes chaos. Low carbs is great for people that have consumed carbs for too long, so they can down regulate glycogen and insulin. People with low body fat usually depend on muscle and muscles store glycogen. So these people would benefit from high carbs until it's time to back off.
Build an effective exercise routine. A good diet is required for your body to be able to maximize your potential, but there's no potential at all until you start the process of tearing down your old muscles and rebuilding them bigger, bulkier, and stronger. The best way to do that is to start at the beginning. If you're not sure where to begin, find a solid workout program online and try it out for a while. Don't immediately jump from one program to the next - you'll end up keeping yourself from making steady progress.
Contrary to certain rumors that animal-based protein is more suitable to trigger muscle growth than plant-based protein, a study by Mangano et al. (2017) could not provide any evidence for this. In contrast, if combined properly, plant-based protein can even have a higher biological quality. A combination of one part wheat protein (e.g. seitan) and two parts soy protein (e.g. tofu) has thus been favored by many bodybuilders. Some bodybuilders, such as Patrik Baboumian and Robert Cheeke, follow a strict vegan diet.[37]
The function of the gluteus maximus is primarily upper leg (thigh) extension, such as moving the upper leg backward—think rising from a squat position. Another way of thinking about this is bringing the torso upright after being hinged forward. Think of a kettlebell swing and you'll get a good visual for the major action of the gluteus maximus muscle.
How to do it: Begin with your head, neck, and shoulders comfortably fixed against a stability or Swiss ball and both feet firmly planted on the ground, knees bent at 90°. (This is also known as table top position.) Either stretch your arms straight up above your chest with your hands clasped to maximize the balance and stability challenge, or down on either side in case you begin to slip or tip over. As with the other bridge motions, simply lower your hips toward the floor then drive them toward the ceiling. Lower and repeat.
In addition to the HIIT sessions, it's always a good idea to go for a 30–60-minute walk as many days per week as you can. I recommend getting a minimum of 10,000 steps every day. Use a phone app to track them. If you're into jogging, swimming, hiking, or some other form of long-duration, fairly low-intensity cardio, that is fine to do as well, and as often as you like.
As a parting thought, we can't emphasize enough the importance of consistency and staying focused. Your workouts shouldn't be two-hour affairs—each visit to the gym needs to be fast-paced and intense. With that as your guide and following the heavy-duty blueprint laid out here, we can't promise it'll be easy, but the results should be worth every drop of sweat. Just think, 10 more muscular pounds may be a mere month away.
In the last week leading up to a contest, bodybuilders usually decrease their consumption of water, sodium, and carbohydrates, the former two to alter how water is retained by the body and the latter to reduce glycogen in the muscle. The day before the show, water is removed from the diet, and diuretics may be introduced, while carbohydrate loading is undertaken to increase the size of the muscles through replenishment of their glycogen. The goal is to maximize leanness and increase the visibility of veins, or "vascularity". The muscular definition and vascularity are further enhanced immediately before appearing on stage by darkening the skin through tanning products and applying oils to the skin to increase shine. Some competitors will eat sugar-rich foods to increase the visibility of their veins. A final step, called "pumping", consists in performing exercises with light weights or other kinds of low resistance (for instance two athletes can "pump" each other by holding a towel and pulling in turn), just before the contest, to fill the muscles with blood and further increase their size and density.
Are you tired of stretching or rolling out tight hip flexors with no improvements? If you are a runner, weight lifter, or team sport athlete, chances are you have heard a teammate or friend complain about having "tight hip flexors". Either that or you yourself have had to deal with the problem. The problem with these tight hip flexors is that people will stretch, stretch, and ……..stretch some more (until the cows come home) and get NO RELIEF. This keeps people in a perpetual cycle of ALWAYS stretching their tight hip flexor with no real permanent relief. The cycle looks something like this:
^ Burd, Nicholas A.; Yang, Yifan; Moore, Daniel R.; Tang, Jason E.; Tarnopolsky, Mark A.; Phillips, Stuart M. (2012). "Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. Micellar casein at rest and after resistance exercise in elderly men". British Journal of Nutrition. 108 (6): 958–62. doi:10.1017/S0007114511006271. PMID 22289570.
A: If your goal is the largest accrual of muscle mass possible then there may be some benefit to ingesting nutrients with a period of 30-60 minutes after your workout. Does this have to be a protein shake? No, but ideally it should be a meal lower in fat to enhance the digest rate of nutrients within the gastrointestinal tract. However, if you have just eaten a mixed macronutrient meal pre-workout then you should keep in mind that that meal is still likely digesting so there's no need to throw down the weights after your last set and rush to your locker to slam a protein shake.
The winner of the annual IFBB Mr. Olympia contest is generally recognized as the world's top male professional bodybuilder. The title is currently held by Shawn Rhoden; it was previously held by Phil Heath, who won every year from 2011 to 2017. The winner of the Women's Physique portion of the competition is widely regarded as the world's top female professional bodybuilder. The title is currently held by Juliana Malacarne, who has won every year since 2014. Since 1950, the NABBA Universe Championships have been considered the top amateur bodybuilding contests, with notable winners such as Reg Park, Lee Priest, Steve Reeves, and Arnold Schwarzenegger. Winners generally go on to become professional athletes.
A sedentary lifestyle can lead to having weak and tight hip flexors as they are always in the shortened position. Tight hip flexors can lead to a limited range of motion, poor posture, lower back, and hip pain, and even injuries. These muscles need to get a workout when you are standing and doing movements such as raising your leg to climb stairs, run, or ride a bicycle.
my name is Samtak and i recently started experimenting with some supplements after about 4-6 months of working out. as of right now i have a protein shake once a day with gainers in the protein powder and am trying to figure out how to use beta alanine and creatine in combination with BCAA. Can anyone help me figure out how to set out a good plan for better effects from these supplements? my current weight is 60 kg and i am 16
Sure, using a more effective workout routine or diet plan will work better/faster than a less effective one. However, even when you're doing everything just right and you've optimized every single major and minor factor to work as quickly and effectively as possible (which I'm going to show you how to do), the simple fact is that you're still not going to build muscle "fast."
The first two weeks of the program are all about lifting heavy with mass-building compound exercises. For everything but abs and calves, reps fall in the 6-8 range; for those accustomed to doing sets of 8-12, this means going heavier than normal. There are very few isolation exercises during this phase for chest, back, shoulders and legs because the emphasis is on moving as much weight as possible to add strength and size.
The real problems begin, however, in poses requiring full extension (straightening) of the hip joint. These poses include backbends such as Setu Bandha Sarvangasana (Bridge Pose) and Urdhva Dhanurasana (Upward-Facing Bow Pose), where both hips are extended, and standing poses like Virabhadrasana I (Warrior Pose I) and Virabhadrasana III (Warrior Pose III), in which the legs open forward and backward (front leg hip flexed, back leg hip extended). In all these poses, tight hip flexors can cause painful compression in the lower back, a fairly common problem in backbends.
"Reg Park's theory was that first you have to build the mass and then chisel it down to get the quality; you work on your body the way a sculptor would work on a piece of clay or wood or steel. You rough it out""the more carefully, the more thoroughly, the better"" then you start to cut and define. You work it down gradually until it's ready to be rubbed and polished. And that's when you really know about the foundation. Then all the faults of poor early training stand out as hopeless, almost irreparable flaws. [..]
Other muscles that can be recruited to assist with hip flexion include the tensor fascia latae (TFL), the pectineus, the adductors, the gracilis, and the anterior aspects of the gluteus medius and the gluteus minimus. The contribution of these secondary hip flexors largely depends on the position of the hip at the time at which movement is initiated.
Weight training aims to build muscle by prompting two different types of hypertrophy: sarcoplasmic and myofibrillar. Sarcoplasmic hypertrophy leads to larger muscles and so is favored by bodybuilders more than myofibrillar hypertrophy, which builds athletic strength. Sarcoplasmic hypertrophy is triggered by increasing repetitions, whereas myofibrillar hypertrophy is triggered by lifting heavier weight.[23] In either case, there is an increase in both size and strength of the muscles (compared to what happens if that same individual does not lift weights at all), however, the emphasis is different.
K. Aleisha Fetters, M.S., C.S.C.S., is a Chicago-based personal and online trainer. She has a graduate degree in health and science reporting from the Medill School of Journalism at Northwestern University and regularly contributes to Men's Health, Women's Health, USNews.com, TIME, and SHAPE. When she's not lifting something heavy, she's usually guzzling coffee and writing about the health benefits of doing so.
All of the gluteals must work to perform this movement—the "deep six" external rotators keep each side of the pelvis stable in spite of the different actions in each hip, and the larger gluteals add additional support for the hips. This move forces your buttock muscles to shore up their connection from the thighs through to the lower back to keep the hips and spine stable.
Perform bent over rows to work your back. Stand with your feet shoulder-width apart, about 6 to 10 inches (15–25 cm) behind the barbell or two dumbbells. Bend slightly at the knees but keep your shins vertical. Bend forward at the waist with your spine and head straight. Lift the weight with an overhand grip up to your lower chest or upper abdomen. Lower slowly until your arms are nearly extended, without touching the ground. 3 x 8.[5]
"Imagine you've fasted for over eight hours," he says. "At breakfast, you're firing your metabolism off really high. If you don't eat for another five hours, your metabolism starts to slow right down and you have to try and kickstart it again with your next meal. If you eat every two and a half to three hours, it's like chucking a log on a burning fire."
^ Burd, Nicholas A.; Yang, Yifan; Moore, Daniel R.; Tang, Jason E.; Tarnopolsky, Mark A.; Phillips, Stuart M. (2012). "Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. Micellar casein at rest and after resistance exercise in elderly men". British Journal of Nutrition. 108 (6): 958–62. doi:10.1017/S0007114511006271. PMID 22289570.
Don't make the mistake of trying to bulk up when you should be on a diet. While you might have muscle on your mind, most people need to get leaner first. If you're fat and you start eating for size, you're only going to get fatter. Get rid of the excess blubber first, to the point where you can see some abs, and then worry about getting big. You should be as low as 12% body fat before you change your diet up to focus on mass gain. That will ensure that your insulin sensitivity is high. When it is, you can eat more carbs and your body won't store them as fat.
How can the muscle progress just because you held a weight for awhile when you could of held a heavier weight for less time? It won't. It won't grow because it's not receiving new tension. Extending the rep by going slower is great, yes, but this slow must be the actual bar speed and not just slow because you can make it slow. You create actual bar speed by making light weight feel heavy. So lift light weight so that the fibers have to switch when it starts to feel heavy. This will increase your strength compared to just lifting heavier right away or all the time. This will help create an actual tempo with actual weights. Remember my example above about how the overall weight after making light weights feel heavy? This is because your muscles have sensed a level of tension that altered its force production so now you have to lift less, yet work harder. Read that again :) this is growth. This is how muscles sense it needs to grow. If you keep the same weight and never increase the weight, then you keep the same tension. This same tension is not enough to create new tension. Remember when I talked about failure? Well, the point where the fatigue of failure comes into play alters as well. It takes less time. That's the point. Not much time is needed for growth, just break down the muscle as much as it can to a healthy level and do it again. Keep doing it and keep trying to increase the weight.


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Here's a Neat Way to Give Out Prizes during a Baby or Bridal Shower
If you're in the process of planning a baby or bridal shower and wondering how to give out unique prizes as gifts for games. Here's a neat way to do it.
This past Sunday, I attended a friend's baby shower and I received the pictured above gift for winning one of the games we played. The card on the gift stated "This is from our shower to yours".
Get it?
As you can tell from the picture the goodies inside were all shower related: shampoo conditioner, bath gel, lotion and hand soap. They were all in the baby shower's color scheme of blue. I thought that was a neat way to gift and give away prizes.
I'll file this away for the next shower I will be giving or involved with. Heck, I'll remember for my own, well that is, whenever that time should come. Ha!
I just thought this was a unique idea and wanted to share it with you ladies. It's so simple, easy, but so cute at the same time, not to mention useful.
Speaking of prizes have you checked out our "Win Stuff" tab lately on our website?
There are so many great prizes we are giving away including: Polaroid Socialmatic digital instant camera, an i-Pod touch, a iPad mini and more!
Click the box below to sign up to win these wonderful prizes.


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Sorry! We couldn't find any service or information that matched what you were looking for.
Find out more
For further information see:
- Possability - Brighton and Hove PA Noticeboard
- Possability - East Sussex PA Noticeboard
- Which? guide to employing private individuals
- Skills for Care - toolkits to guide you through the process of recruiting, managing and training your PA(s)
- East Sussex County Council - Someone to speak up for you - Independent advocacy services


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411 3rd Avenue Se, Swift Current
Location - Close to K-Gr.12 Schools!
Location - Close to Elmwood Golf Course!
Location - Close to park and walking path!
This Bungalow has it all! 2 bedrooms plus bedroom/den that features garden doors that takes you to the totally decked & fenced yard, and best of all - the Hot Tub. Recent updates: 2015 - HE furnace, On Demand water-heater, exterior with new stucco/rock, front steps and sidewalks redone with color - rock. 2018 Bathrooms totally renovated with new fixtures and taps. Main bath features the "Claw Tub" from the 20's. Sunken living-room/gas fireplace, abundance of white cabinet makes this home ideal for the family or retiree's. Basement features family-room/gas fireplace, hobby-room, 4 pc bath/jet-tub and large utility-room. Lets not forget the large single garage that has an electric winch in the ceiling, ready for the Handi-man. Covered car-port between the home and garage gives you lots of off street parking. Ready to move into! Heat equl. $90/month (Includes Garage)
Air Conditioner (Central), On Demand Water Heater
Asphalt, Concrete Drive, Single Drive
1 Car Detached, Carport, Parking Pad, Parking Spaces
Fridge, Stove, Washer, Dryer, Dishwasher Built In, Garage Door Opnr/control(s), Hood Fan, Hot Tub, Microwave, Shed(s), Window Treatment
Garden Area, Lawn Front, Patio(S), Trees/Shrubs
Realty Executives Preferred Choice
The Association of Regina REALTORS® Inc. (ARR) IDX listings are displayed in accordance with ARR's MLS® Data Access Agreement and are copyright of the Association of Regina REALTORS® Inc.
The above information is from sources deemed reliable but should not be relied upon without independent verification. The information presented here is for general interest only, no guarantees apply.
MLS® System data of the Association of Regina REALTORS® Inc. displayed on this site is refreshed every 15 minutes.


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Refresh is the world's leading dwelling renovation builder. Normally, house renovations requiring Growth Software (DA) approval will be surveyed for hazardous materialsiii. I've used IKEA items as the base for my tasks many occasions, from my cupboard workspace resolution to my kiddos' toy storage , and shortly within the research at my new house.
Constructing materials and tools cover: This covers the supplies and tools saved at the property, including items that have not but been fitted like kitchen items. These are the smart phrases that the individuals behind these construction fails most likely should have heard before enterprise any of the next initiatives.
The recognition of actuality exhibits that reveal dramatic residence renovations has skyrocketed, turning HGTV into some of the successful cable networks From Trading Areas to Property Brothers, there is no such thing as a scarcity of fixer-higher programming to binge on.
Renovations are a really perfect opportunity to evaluation your own home loan and see if it nonetheless fits your needs. Courses will probably be of curiosity to anybody who has a house venture that they want to sort out as well as to contractors wanting to add to their enterprise companies referring to home renovations.
Remind your contractor to not use powered mechanical gear, carry out hammering or handle rubble between 7 pm to 7 am or at any time on public holidays. As much as $2,000 of the $10,000 renovation grant can be used to buy family goods. A proper renovation should be rigorously orchestrated to reduce disruption and keep your day-to-day schedule as regular as possible.


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What kind of executive are you if you don't know about what goes in your admin until you hear about in the media?
— Jay Caruso (@JayCaruso) May 19, 2014
A pretty lousy kind — and, according to press secretary Jay Carney, the kind that's currently occupying the White House. Confronted about the developing Veterans Affairs scandal during today's press briefing, Carney reassured the press corps — and thus the country — that President Obama only found out about it recently. From the news, natch:
VIDEO: White House: Obama Learned About The VA Scandal From News Reports http://t.co/8c5SBghd37
— Webber Steinhoff (@webbersteinhoff) May 19, 2014
Reporter: "When was the president first made aware of these problems, these fraudulent lists that were being kept to hide the wait times? When was he first made aware of those problems, and when did other White House officials — top White House officials — become aware of these problems?"
Carney: "If you mean the specific allegations that I think were reported first by your network out of Phoenix, I believe, we learned about them through the reports. I will double check if that's not the case, but that's when we learned about them."
Sound familiar? It should.
'We learned about it on the news' — @PressSec Umm, we've heard this before.
— Sarah Isgur Flores (@whignewtons) May 19, 2014
This isn't the White House's first time playing the ignorance card before. And just like back then, citizens are calling B.S.:
If this admin STILL gets all of it's info from the freaking news, they're not just inept–they occupy jobs they shouldn't have.
— Krystle (@TarheelKrystle) May 19, 2014
Obama's administration is set up like a caporegime. Keep as many buffers between the President and his incompetent people as possible.
— Matt (@Matthops82) May 19, 2014
Shorter Carney: President Obama never knows what's going on in his administration, country, or world if it doesn't occur in pop culture.
— Matt (@Matthops82) May 19, 2014
Admin claiming Obama isn't paying attention to what happens with VA? Bold move considering https://t.co/o2WYBDYLJ4
— Stephen Miller (@redsteeze) May 19, 2014
But Michael Sam.. RT @rickklein: Carney on VA scandal: "I'm sure you'll hear from him on this at some point soon."
— Stephen Miller (@redsteeze) May 19, 2014
If it's on ESPN, @BarackObama is fucking ON IT! Everything else.. Derp.
— Stephen Miller (@redsteeze) May 19, 2014
Commander in Chief of US MILITARY.. Learned of veterans deaths while reading jus iPad in the bathroom., that's what we're being told.
— Stephen Miller (@redsteeze) May 19, 2014
Take comfort, though:
When will @BarackObama speak on VA scandal? @PressSec says, "I am sure you will hear from him at some point"
— Jonathan Karl (@jonkarl) May 19, 2014
The White House is on it!
At "some point soon" President Obama will speak out as a detached observer to what is happening under his leadership in his administration.
— Rory Cooper (@rorycooper) May 19, 2014
We're in capable hands, America.
Can we safely conclude that these problems have been allowed to get worse BECAUSE Obama only learns about them from the news?
— RB (@RBPundit) May 19, 2014
Hogwash: President Liar Pants claims he heard about IRS targeting conservatives 'from news'
'This country has failed its veterans!' Stacey Dash appalled by deaths at Phoenix VA
Actor Ken Wahl: Instead of fundraising, Obama should visit corrupt Phoenix VA
Dean Cain: 'Like Obamacare? Check out the VA hospital scandal'
Read more: http://twitchy.com/2014/05/19/news-to-us-jay-carney-says-obama-learned-of-va-scandal-from-media-reports-video/


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We've stocked up on items to help you create the perfect cocktail party, picnic, boating trip or camping excursion. We have a wide variety of specialty cheeses, including amazing selections from Cowgirl Creamery and Nettle Meadow. Check out our wide selection of crackers, cheese straws and pickled veggies from Stonewall Kitchen. For fans of Oscar's […]
Jeopardy Happy Hour
Introducing Jeopardy Hour – 6pm-7.30pm Thursday & Friday Join us each Thursday and Friday and play along with Jeopardy! All Wine/Beer/Cider beverages available for 25% off at the Libations Bar! If you get the correct answer to the 'Final Jeopardy' question, you'll get a free drink! Jeopardy airs at 7pm. Enjoy dinner or apps along […]
New Well Dressed Food Coffees
We've partnered with Adirondack Coffee Roasters to create four special blends for Well Dressed Food. We use the Dark Roast and Dark Roast Decaf for our Espresso Bar, and all four varieties are available whole bean or ground to order in the store. We hope you'll check them out!
Tupper Lake Trivia at Well Dressed Food
Join us for Tupper Lake Trivia night at Well Dressed Food! You can find the current schedule here. We'll provide free warm tortillas & salsa while you test your skills and enjoy the game… Craft Beer, Wine & our full menu will be available. We hope you can join us!
Holiday Gatherings
Planning a Holiday Party or Gathering? Let us help! We have deli platters, wing platters, chicken tender platters, appetizers, pies and full prepared meals to make your event special. Give us a call on 518-359-5280 to discuss how we can help you!
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Tron (TRX) CEO and Founder Justin Sun (Justin Sun) said that this year Tron will "officially collaborate" with Ethereum (ETH). Sun made this announcement during the last Crypto Chick podcast on April 6th.
When Sun was asked what he thought of Ethereum co-creator Vitalik Buterin's recent trolling of Tron project, Sun declared that any competition between Tron and Ethereum is ultimately going to help the cryptocurrency space in the long term. He noted: "First of all, everybody knows that Tron and Ethereum compete in the Dapp, for sure. But I think definitely that this competition will result in a better product – the competition between Ethereum and Tron benefits the whole industry."
The tweet was that Buterin pose next to a giant poster of Justin Sun, with the sarcastic message: "Toward a brighter tomorrow.": Before that Justin Sun trolled Vitalik by means of avocado speech.
There's no extra commission fee for trade operations. Trade without limits
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Such tool as "Trailing" allow you to get extra income without wasting of time


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Game Balance Designer (World of Tanks Blitz)
Wargaming's World of Tanks Blitz team is looking to hire a Game Balance Designer for the Design department. We're a tightly-knit group of professionals who're really into playing and creating games and perfecting them by using statistical data and our expertise.
As a Game Balance Designer, you will fine-tune the tanks' stats and other peculiarities allowing them to perform their role on the battlefield. You will develop and improve the tank gameplay concept together with other designers and analysts.
What will you do?
Fine-tune the tanks' stats and other parameters including the economic ones
Develop the tanks' gameplay concepts
Develop strategies aimed at evolving the tank gameplay
Gather and process gameplay-related statistical data
Interact with operating and testing teams, and the art department
What are we looking for?
1+ years' experience as a game balance designer/game designer
Avid World of Tanks Blitz and/or World of Tanks player (5,000+ battles, at least one Tier X vehicle of every class)
Understanding of World of Tanks Blitz gameplay and mechanics
Bachelor's degree in engineering, mathematics or economics
Advanced Microsoft Excel user
Knowledge of statistics
What additional skills will help you stand out?
Experience working with SVN
Broad gaming experience in various genres featuring classes (action, RPG, etc.)
About Wargaming
Wargaming is an award-winning online game developer and publisher headquartered in Nicosia, Cyprus. Operating since 1998, Wargaming has grown to become one of the leaders in the free-to-play MMO gaming industry with 4500+ employees and offices spread all over the world. Over 200 million players enjoy Wargaming's titles across all major gaming platforms, including the massively popular World of Tanks and World of Warships.
Working in our company means always having interesting challenges and gaining valuable experience while working with top-class experts.
Take your place among our passionate and experienced team and bring out the best in yourself at Wargaming!
Please see Wargaming Candidate Privacy Policy for details on how Wargaming uses your personal data.


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Thermo Fisher technical specialists can help you select the right assay, create a custom assay, and more. Contact us
Analytical sensitivity
<0.025 ng/mL
Assay range
0.16-10 ng/mL
Sample type/volume
Cell Lysate
10 µL
Hands-on time
1 hr 20 min
4 hr
Homogenous (no wash)
Interassay CV
Intraassay CV
Colorimetric Microplate Reader
Product size
96 tests
Pre-coated 96 well plate
Standard Dilution Buffer
Detection Antibody
HRP Diluent
Wash Buffer
Stop Solution
Adhesive Plate Covers
Shipping condition
Wet Ice
Protein name
Target sub-specificity
Protein aliases
CREB-1, cAMP-responsive element-binding protein 1
Protein family
Transcription Factors
Species (tested)
Human, Mouse
Assay kit format
Sandwich ELISA Kit
Detector antibody conjugate
Label or dye
Gene aliases
2310001E10Rik, 3526402H21Rik, AV083133, Creb, Creb-1, CREB, CREB-1
Gene ID
Gene symbol
Creb1, CREB1
UniProt ID
The Human CREB (Total) ELISA Kit is a solid-phase sandwich Enzyme-Linked Immunosorbent Assay (ELISA) designed to detect and quantify the level of CREB (Total) in fresh or frozen human cell lysates. Cross-reactivity has been observed in mouse cells. The assay recognizes both natural and recombinant CREB (Total), independent of its phosphorylation state.
Principle of the method
A monoclonal capture antibody specific for CREB (Total) has been coated onto the wells of the 96-well plate. During the first incubation, standards of known content and unknown samples are pipetted into the wells and the antigen binds to the immobilized (capture) antibody. After washing, a rabbit antibody specific for the target protein is added to the wells and serves as a detection antibody by binding to the immobilized protein captured during the first incubation. After washing, a horseradish peroxidase labeled anti-rabbit IgG is added. This binds to the detection antibody to complete the four member sandwich. After a third incubation and washing to remove all the unbound enzyme, a substrate solution (TMB) is added, which is acted upon by the bound enzyme to produce color. The intensity of this colored product is directly proportional to the concentration of target protein present in the original specimen and the optical density can be read on a standard microplate reader.
Rigorous validation
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
CREB (Cyclic AMP response element binding protein) is a 43 kDa basic/leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation of CREB occurs via p44/42 MAP kinase and p90RSK, and via p38 MAP kinase and MSK1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB is involved in different cellular processes including the synchronization of circadian rhythmicity, differentiation of adipose cells, and learning and memory. In humans, the gene is located on the q arm of chromosome 2. Diseases associated with CREB dysfunction include Alzheimer's Disease, histiocytoma and soft tissue melanoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.


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Almost every person at least once in his life used tequila, or at least heard of its existence. In recent years, this Mexican alcoholic drink has gained wide popularity and is readily consumed far beyond the borders of the motherland. We invite you to take a closer look at this alcoholic beverage.
1. Real tequila is made from the juice of Blue Agave (Agave Tequilana Weber).
2. For cutting the leaves of the Blue Agave, a special machete is used, it is called "Coa", and has round blades.
3. Men who are engaged in the collection of agaves and use Machete Coa called Jimadors.
4. From the core (or pina) of the agave, raw materials for the production of tequila are obtained. Its weight can reach 90 kg.
5. In the mid-20th century, in California, the false belief that tequila had psychedelic properties spread. Fallacy occurred as a result of confusion in the name of the beverage ingredients, Californians confused mescal with mescaline (peyote psychoactive alkaloid).
6. Physicists at the National University of Mexico invented a way to create artificial diamonds from tequila. Unfortunately, synthetic diamonds are too small to turn into jewelry, but they can be used for industrial purposes.
7. A closed bottle of tequila can be stored for a long time. After opening, the drink is stored for one or two months until the drink oxidizes and evaporates, and the quality of tequila will be irretrievably lost.
8. Some varieties of tequila in the modern world are produced using ancient methods. Some premium tequila manufacturers, such as Patr N, are still using old-fashioned technology, in which 2-tonne wheels made of volcanic stone slowly squeeze juice from the core of the agave. The juice and fibers of blue agave are then placed in pine barrels for further fermentation. More than 60 pairs of hands will touch each bottle before it is sent to the warehouse.
9. Just as true champagne must come from France, tequila must be made exclusively in Mexico, usually in the state of Jalisco. For the production of tequila, the states of Guanajuato, Michoacan, Nayarit and Tamaulipas are considered acceptable.
10. The most common misconception is the opinion that the bottom of the bottle with this tequila should be a worm. In fact, the worm, or gusano, can be found in lower-quality tequila, for example in mescal, and it is used rather as a marketing ploy. Gusano are the larvae of a species of moth that lives on agave.
11. Jose Cuervo was the first to commercialize the tequila market. He is no less real than Jack Daniels, Jim Beam, or Captain Morgan.
12. A diamond-encrusted bottle of "Hacienda La Capilla" is the most expensive tequila in the world, costing about $ 3.5 million.
13. According to the laws of Mexico, tequila must contain at least 51% of the juice of blue agave.
14. Famous actor George Clooney owns his own brand of tequila.
15. July 24 is National Tequila Day.
16. Many people assume that tequila is made from cactus, but in fact agave is a lily.
17. Until the agave becomes suitable for making tequila, it should take about 8 years. It reaches a maturity level suitable for procurement and use in beverage production.
18. The Mexican government has exclusive rights to the name "Tequila".
19. With moderate use of tequila activates the nervous system, and never creates a depressed mood.
20. Tequila is one of the few things that foreigners consider to be uniquely Mexican.