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Immune Response
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siRNA Immunological Fishing Training (SIFT) Experience as a Novel Research Education Tool for Students Studying Immunology †
- Authors: Diana M. Elizondo, Temesgen E. Andargie, Dineeta S. Kubhar, Karis M. Marshall, Aamir M. Zariwala, Clarence M. Lee, Michael W. Lipscomb*
Citation: Elizondo D, Andargie T, Kubhar D, Marshall K, Zariwala A, Lee C, Lipscomb M. 2017. Sirna immunological fishing training (sift) experience as a novel research education tool for students studying immunology † . 18(1): doi:10.1128/jmbe.v18i1.1288
- DOI 10.1128/jmbe.v18i1.1288
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This report describes an innovative research education tool for student exposure and training in immunology. Utilizing the wealth of transcriptomics data provided through the immunological genome project, graduate and undergraduate students can engage in hands-on experimental studies to identify and rigorously characterize novel genes in immune cells using RNA interference-mediated approaches. The SIFT activities are directly aligned with cell biology and immunology courses and serve to reinforce and expand on the foundations learned. Furthermore, the student-driven studies provide a sense of ownership and largely expose students to the breadth of experimental research approaches in the biological sciences. Finally, generation of original datasets supports the greater scientific community by contributing in assembly and delineation of the regulatory networks that govern immunity.
Toll-Like Receptor Signaling and Its Inducible Proteins
- Authors: Takashi Satoh, Shizuo Akira
Citation: Satoh T, Akira S. 2016. Toll-like receptor signaling and its inducible proteins. 4(6): doi:10.1128/microbiolspec.MCHD-0040-2016
- DOI 10.1128/microbiolspec.MCHD-0040-2016
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Studies that bridge innate immunity and various diseases are making rapid advances. Macrophages and dendritic cells play a leading role in innate immunity, using pattern recognition receptors (PRRs) to sense both pathogen invasion and danger signals. Among these PRRs, the Toll-like receptors (TLRs) play a central role in the immune response by recognizing not only pathogen-associated molecular patterns from bacteria and viruses but also damage-associated molecular patterns from dying or injured cells. These TLR family molecules facilitate not only the elimination of pathogens but also the development of various disorders, including arteriosclerosis, cancer, and metabolic syndrome. TLRs activate signaling pathways that result in the production of cytokines, chemokines, and various inducible molecules associated with the immune response. Although most components of the innate immune signaling pathways, such as the TLR family and its downstream signaling, have been identified, the physiological roles of many TLR signal-inducible proteins remain unclear. Recent studies have shown that some TLR-inducible proteins are critical in the immune response and the development of various disorders. In this review, we focus on the TLR signaling pathways and the roles of some TLR-inducible proteins.
A Cost-Effective Approach to Producing Animated Infographics for Immunology Teaching †
- Authors: Maria Bellei*, Paul Welch, Sally Pryor, Natkunam Ketheesan
Citation: Bellei M, Welch P, Pryor S, Ketheesan N. 2016. A cost-effective approach to producing animated infographics for immunology teaching † . 17(3):477-479 doi:10.1128/jmbe.v17i3.1146
- DOI 10.1128/jmbe.v17i3.1146
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Multimedia resources such as video and animations are increasingly used to enhance student engagement and understanding, particularly when teaching cognitively complex concepts. However, the creation of animation is time-consuming and hence, expensive compared to the creation of graphics. Recognizing this and the challenges students face in learning immunology, we describe here a process of a multi-disciplinary collaboration that produced a series of 3-minute animated infographics videos for tertiary-level immunology teaching within an Australian university. We evaluate the benefit of these and their merit as supplemental curriculum resources to enhance learning.
What Seemed Important in 1966?
- Author: Bernard Dixon
- Publication Date : September 2016
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Author: Bernard DixonPublication Date : September 2016 DOI 10.1128/microbe.11.372.1Abstract:
Half a century ago, I was in Moscow, in the then Soviet Union, attending an International Congress of Microbiology. Although the passing of time seems unbelievable, the interval provides an opportunity to reconsider key topics which the organizers chose to focus attention on, since they were then major concerns for the profession. Some of those topics now appear surprising, some have declined in importance, and others have become more so.
Vaccine Adjuvant Fails to Protect Obese Mice against Influenza
- Publication Date : September 2016
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Publication Date : September 2016 DOI 10.1128/microbe.11.380.4Abstract:
An mBio study demonstrates that adjuvants can increase a host's immune response during influenza vaccination, but not enough to protect the obese against infection. "Adjuvants increased the antibody responses to levels considered protective, yet obese mice still succumbed to infection," says first author Erik Karlsson. "The immune response in our obese animals is reminiscent of the elderly, in that you can increase it but there's something wrong with it," says lead scientist Stacey Schultz-Cherry. "We need to focus on understanding why this happens and how to overcome this problem." The study was a collaboration between scientists at St. Jude Children's Research Hospital in Memphis, Tenn., and Ben-Gurion University of the Negev in Be'er-Sheva, Israel.
Immune Responses to Viruses and Vaccines Differ Between Men and Women
- Publication Date : September 2016
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Publication Date : September 2016 DOI 10.1128/microbe.11.383.1Abstract:
Human sex differences extend beyond anatomy to encompass important immune system functions, predisposing men and women to respond differently to infectious diseases. For instance, estrogens tend to promote stronger inflammatory, cellular, and humoral immune responses in women than men. While robust immune responses to pathogens can benefit the host, overexuberant inflammatory responses can damage host tissues—predisposing women more than men to develop immunopathologies, comorbidities, autoimmune disorders, and adverse reactions to vaccines, among other deleterious effects.
Anti-TNF Therapy
- Authors: Irina Udalova, Claudia Monaco, Jagdeep Nanchahal, Marc Feldmann
Citation: Udalova I, Monaco C, Nanchahal J, Feldmann M. 2016. Anti-tnf therapy. 4(4): doi:10.1128/microbiolspec.MCHD-0022-2015
- DOI 10.1128/microbiolspec.MCHD-0022-2015
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Tumor necrosis factor (TNF) is one of the most important cytokines produced by macrophages. TNF is a very important component of host defense, released very rapidly after all types of injuries and stimuli. The kinetics of TNF release are short, and so it is perhaps not surprising that prolonged TNF production is associated with pathology. This was first elucidated in rheumatoid arthritis but extends to other chronic inflammatory diseases such as Crohn's disease and psoriasis. In this chapter, the discovery of anti-TNF therapy is reviewed, with its benefit but also its limitations. The potential of anti-TNF therapy in other diseases, e.g., cardiovascular and fibrosis, is discussed, as is the opportunity to define ways of blocking TNF synthesis.
Host-Targeted TB Therapies of Limited Efficacy So Far
- Publication Date : August 2016
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Publication Date : August 2016 DOI 10.1128/microbe.11.335.1Abstract:
Mycobacterium tuberculosis (Mtb) is notoriously difficult to eradicate even with combinations of antibiotics, leading researchers to pursue alternate strategies, including one aimed at bolstering host defenses against this pathogen. "Our inability to effectively treat all infected individuals necessitates a deeper understanding of the host-pathogen interface to facilitate new approaches," says Amy Barczak of the Ragon Institute and Massachusestts General Hospital in Boston, Mass. She was one of several experts who participated in the symposium "Aiming at Non-Conventional Approaches to TB Therapies," held at the 2016 ASM Microbe Conference in Boston last June.
Tracking How Bacteria Threaten Newborns
- Publication Date : August 2016
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Publication Date : August 2016 DOI 10.1128/microbe.11.340.4Abstract:
A scientific team led by Lakshmi Rajagopal at the University of Washington in Seattle has found that hyaluronidase allows group B streptococci (GBS) to avoid immune detection from the host during pregnancy. First author Jay Vornhagen used a mouse model of preterm birth to determine the role of this virulence factor, which breaks down hyaluronic acid and block toll-like receptor activation. "The host's immune system seems to be unable to recognize GBS, and therefore does not mount an effective immune response," says Rajagopal. Understanding the factors that allow vaginal flora to switch from commensal colonizers to ascending pathogens will help scientists develop methods to block this switch and prevent preterm birth. The study is available in mBio.
Beating the Odds: the Journey of an African-American Microbiologist
- Author: Howard M. Johnson
- Publication Date : August 2016
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Author: Howard M. JohnsonPublication Date : August 2016 DOI 10.1128/microbe.11.343.1Abstract:
I am an internationally recognized immunologist and microbiologist, who has had the good fortune to contribute significantly to research within my discipline. Before I could do so, I had to escape the confines of the American version of an apartheid system, into which I was born in 1936, near Annapolis, Md. This part of the country was then unabashedly racist and remained so throughout the years of my primary and secondary schooling.
Susceptibility to Urinary Tract Infection: Benefits and Hazards of the Antibacterial Host Response
Citation: Ambite I, Nagy K, Godaly G, Puthia M, Wullt B, Svanborg C. 2016. Susceptibility to urinary tract infection: benefits and hazards of the antibacterial host response. 4(3): doi:10.1128/microbiolspec.UTI-0019-2014
- DOI 10.1128/microbiolspec.UTI-0019-2014
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A paradigm shift is needed to improve and personalize the diagnosis of infectious disease and to select appropriate therapies. For many years, only the most severe and complicated bacterial infections received more detailed diagnostic and therapeutic attention as the efficiency of antibiotic therapy has guaranteed efficient treatment of patients suffering from the most common infections. Indeed, treatability almost became a rationale not to analyze bacterial and host parameters in these larger patient groups. Due to the rapid spread of antibiotic resistance, common infections like respiratory tract- or urinary-tract infections (UTIs) now pose new and significant therapeutic challenges. It is fortunate and timely that infectious disease research can offer such a wealth of new molecular information that is ready to use for the identification of susceptible patients and design of new suitable therapies. Paradoxically, the threat of antibiotic resistance may become a window of opportunity, by encouraging the implementation of new diagnostic and therapeutic approaches. The frequency of antibiotic resistance is rising rapidly in uropathogenic organisms and the molecular and genetic understanding of UTI susceptibility is quite advanced. More bold translation of the new molecular diagnostic and therapeutic tools would not just be possible but of great potential benefit in this patient group. This chapter reviews the molecular basis for susceptibility to UTI, including recent advances in genetics, and discusses the consequences for diagnosis and therapy. By dissecting the increasingly well-defined molecular interactions between bacteria and host and the molecular features of excessive bacterial virulence or host-response malfunction, it is becoming possible to isolate the defensive from the damaging aspects of the host response. Distinguishing "good" from "bad" inflammation has been a long-term quest of biomedical science and in UTI, patients need the "good" aspects of the inflammatory response to resist infection while avoiding the "bad" aspects, causing chronicity and tissue damage.
Tumor-Induced Myeloid-Derived Suppressor Cells
- Authors: Francesco De Sanctis, Vincenzo Bronte, Stefano Ugel
Citation: De Sanctis F, Bronte V, Ugel S. 2016. Tumor-induced myeloid-derived suppressor cells. 4(3): doi:10.1128/microbiolspec.MCHD-0016-2015
- DOI 10.1128/microbiolspec.MCHD-0016-2015
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Myeloid-derived suppressor cells (MDSCs) represent a heterogeneous, immune-suppressive leukocyte population that develops systemically and infiltrates tumors. MDSCs can restrain the immune response through different mechanisms including essential metabolite consumption, reactive oxygen and nitrogen species production, as well as display of inhibitory surface molecules that alter T-cell trafficking and viability. Moreover, MDSCs play a role in tumor progression, acting directly on tumor cells and promoting cancer stemness, angiogenesis, stroma deposition, epithelial-to-mesenchymal transition, and metastasis formation. Many biological and pharmaceutical drugs affect MDSC expansion and functions in preclinical tumor models and patients, often reversing host immune dysfunctions and allowing a more effective tumor immunotherapy.
Infecting Pregnant Mice Disrupts Fetal Brain, Inducing Autism
- Publication Date : May 2016
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Publication Date : May 2016 DOI 10.1128/microbe.11.194.1Abstract:
Infecting pregnant mice can activate immune responses that disrupt fetal brain development, causing autism spectrum disorder (ASD)-like syndrome in newborn mice, according to Gloria Choi of Massachusetts Institute of Technology in Cambridge, Mass., and her collaborators there and at several other institutions. The inflammatory cytokine IL-17a orchestrates that pathology, a finding with implications for preventive and therapeutic strategies if the mechanism in mice applies to humans, they say. Details appeared online 28 January 2016 in Science (doi: 10.1126/science.aad0314).
Metalloproteinases: a Functional Pathway for Myeloid Cells
- Authors: Jonathan Chou, Matilda F. Chan, Zena Werb
Citation: Chou J, Chan M, Werb Z. 2016. Metalloproteinases: a functional pathway for myeloid cells. 4(2): doi:10.1128/microbiolspec.MCHD-0002-2015
- DOI 10.1128/microbiolspec.MCHD-0002-2015
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Myeloid cells have diverse roles in regulating immunity, inflammation, and extracellular matrix turnover. To accomplish these tasks, myeloid cells carry an arsenal of metalloproteinases, which include the matrix metalloproteinases and the adamalysins. These enzymes have diverse substrate repertoires, and are thus involved in mediating proteolytic cascades, cell migration, and cell signaling. Dysregulation of metalloproteinases contributes to pathogenic processes, including inflammation, fibrosis, and cancer. Metalloproteinases also have important nonproteolytic functions in controlling cytoskeletal dynamics during macrophage fusion and enhancing transcription to promote antiviral immunity. This review highlights the diverse contributions of metalloproteinases to myeloid cell functions.
IFITIM3 Genes Mediate Innate Immune Response of to Influenza Virus
- Publication Date : January 2016
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Publication Date : January 2016 DOI 10.1128/microbe.11.12.1Abstract:
Insights into the avian immune response may reveal manipulations to keep threats to people at bay. Research conducted at the University of Alberta and published in the Journal of Virology focused on the innate immune response of ducks, one of the natural hosts of influenza A virus (IAV). A family of proteins known as interferon-inducible transmembrane proteins (IFITMs) act as part of the innate immune response in ducks. Scientists in Katharine Magor's lab identified four duck IFITM genes, which were exogenously expressed in chicken cells for characterization. One of the proteins, IFITM3, colocalized with the endosomal marker LAMP1. Endosomal localization allows IFITM3 detection of IAV entering the cell via endocytosis, and ifitm3 expression protected the cells from IAV infection better than other, nonendosomal IFITM homologs. This protection appears to be IAV-specific, as expression did not protect against infection with vesicular stomatitis virus (VSV), a virus that also enters via endocytosis. The scientists concluded that IFITM3, which has homologs found in pigs and humans, is important for the duck immune response to influenza virus infection.
Skin Microbiome Influences Common Sexually Transmitted Disease
- Publication Date : October 2015
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Publication Date : October 2015 DOI 10.1128/microbe.10.411.2Abstract:
In the first such prospective study, Stanley Spinola and Julia van Rensburg of Indiana University School of Medicine, Indianapolis show that individuals with a particular skin microbiome can effectively clear bacteria that cause chancroid, a sexually transmitted disease common in developing countries that has been linked to enhanced HIV transmission. They infected eight volunteers on the arm with Haemophius ducreyi, sampling the microbiome before, during, and after infection. Four volunteers resolved the infection, and four formed abscesses. Resolvers all had similar microbiomes prior to infection, while the microbiomes of those who formed abscesses were different from one another prior to infection, becoming more similar as infection proceeded. "This suggests that the immune response to H. ducreyi infection causes the microbiomes to become more similar," say Spinola and van Rensburg. They suggest that the more prevalent bacteria in the resolvers may protect the skin by outcompeting the pathogen, by keeping the immune system primed to fight invaders, or may reflect a more resistant immune system. Ultimately, the skin microbiome could be used to identify people at risk for infection, says Spinola.
Minitopics:Microbiology Policy Bulletin Board
- Publication Date : August 2015
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Publication Date : August 2015 DOI 10.1128/microbe.10.313.2Abstract:
Recent national and international developments involving microbiology and related science policy matters include:
Reflecting a continuing concern over antibiotic resistance issues, the Obama administration in June invited representatives from more than 150 food companies, retailers, and human and animal health stakeholders to a "White House Forum on Antibiotic Stewardship." The President also signed a memorandum directing federal departments and agencies to create "a preference for meat and poultry produced according to responsible antibiotic use."
In a related development, officials of the Food and Drug Administration plan to expand data collection on the use of antibiotics in agriculture.
Further, the National Institutes of Health and the Biomedical Advanced Research and Development Authority in June announced a competition in which up to $20 million could be made available for the delivery of one or more successful rapid point-of-care diagnostics that may be used by health care providers to identify bacterial infections.
The World Health Assembly (WHA) in May adopted a global action plan on antimicrobial resistance, urging member states to implement compatible national action plans within two years.
WHA also called on member nations to allocate adequate resources for introducing vaccines and developing immunization programs.
Back at the national level, several members of the House of Representatives Energy and Commerce Committee are continuing to question Centers for Disease Control and Prevention Director Tom Frieden and Secretary of Defense Ashton Carter about incidents in which samples containing "live anthrax" were mistakenly shipped "to nearly twice as many states and three times as many countries as originally reported, [including] 51 labs in 17 states and 3 foreign countries," the committee members note.
Rockefeller University's Role in the Development of the First Vaccines Against Meningococcal Meningitis
- Author: Wynne Parry
- Publication Date : August 2015
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Author: Wynne ParryPublication Date : August 2015 DOI 10.1128/microbe.10.338.1Abstract:
Shortly after laboratories opened at the newly founded Rockefeller Institute for Medical Research in New York City, meningococcal meningitis spread through the city. About 4,000 cases of this disease, which frequently killed or severely disabled its victims, were documented in 1904 and 1905. At the time, these grim numbers were nothing extraordinary, as periodic outbreaks of diphtheria, smallpox, and other infectious diseases rippled through New York and elsewhere around the world.
- Publication Date : July 2015
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Publication Date : July 2015 DOI 10.1128/microbe.10.271.2No descriptions available.
Outbreak Spurred Several Approaches to Developing Ebola Therapeutic Products
- Author: Jeffrey L. Fox
- Publication Date : July 2015
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Author: Jeffrey L. FoxPublication Date : July 2015 DOI 10.1128/microbe.10.274.1Abstract:
Several distinct types of Ebola therapeutic products are under development—some more or less conventional antiviral agents, while others depend on more recently developed techniques to disrupt viral gene activity or use antibodies to bind the virus and trigger host immune responses.


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TKO is Here!
December 11, 2017
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Compete in more events and have more fun!
Download the "Player Setup Guide" here.

subset: commoncrawl


text: Chiffonier lumber arrives Posted on December 3, 2012 by villagecustomfurniture Who's in the house? The lumber is in the house! Say it with me. The lumber is in the house! Raise the roof! Ok…settle down…I know you are excited. Me too. Here's a look: Now it acclimates… – JR Advertisements Share this:EmailPrintTweetLike this:Like Loading... Related


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BALLER MOVE: Add in Deeper Leagues
ANALYSIS: Kolten Wong is a fine looking second baseman that the Cardinals have been eager to bring up to the big club, but have resisted because he just wasn't ready last year. To be perfectly honest, I'm still not sure that he is ready to be an everyday fantasy second baseman, and in redraft leagues I would let someone else assume that risk. But he had a scorching hot spring, and has had a decent start to the regular season with a stat line of .257, 2 RBI, 2 Runs and 2 SB. Wong has demonstrated very good plate discipline during this brief season amassing a .350 OBP and has even stolen a couple of bases. Wong's upside appears to be similar to Daniel Murphy of the Mets, but the batting average is probably at least a year away. He is someone to consider off the waiver wire, but personally I would only take him in deep leagues as a MI or in NL-Only formats.
Check out RotoBaller's entire fantasy baseball waiver wire pickups and sleepers list, updated daily!


text: We promised to update the website every week and will continue to do so even when, as is the case right now, there is not a lot to say. Good news is that the work on the building is progressing and is scheduled to be finished by next Wednesday. No glitches so far!


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Bill 30 Part V - Reporting Incidents
Onsite Safety Management Inc.
Employers are required to report serious incidents, injuries, and fatalities to the government so that investigations can be done in order to qualify any wrong as a crime the should be. This investigation seeks to stop this incident from happening in the future. Employers are now also required to report near misses.
While these investigations are important to the development of safety practices they can be lengthy and it's much better for all of us to practice prevention. In my experience it is in the hands of the workers to take reports seriously. If enough workers take safety seriously it will force the company to take it seriously.


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Gross Profit
Financial Indicator
Gross Profit
Cost of Revenue
Gross Profit In A Nutshell
Profit margin is a number that you can use along with gross profit, but understanding what drives the numbers is key. Obviously there is sales and the ability of the company to make money. If you see that sales and revenue have been slipping, then the gross profit number will likely be slipping as well.
Gross profit is an important number to look at when fundamentally evaluating a stock. Gross profit is simply total revenue with the cost of goods sold subtracted. A company needs to maintain these types of numbers as it is what appeals to investors. Fundamentally understanding a stock is fairly simple, but it is what you are looking for that is important.
Closer Look at Gross Profit
In todays current market, we can use the example of retail and where you may find that gross profit is struggling. Take the time to figure out why it is this way and apply it to other areas of the market. Learning more than once area of the market will help you become a well rounded fundamental researcher.
If you are not already, find a piece of material to read on a regular basis that uses gross profit and other fundamental numbers, that way you can become comfortable with the way people use them in their research. Consult with an investing community and interact with the people as many of them may have multiple years experience. If all else fails, reach out to an investing professional and they should be able to point you in the right direction. Gross profit is an excellent tool and should be once that you keep handy in your investing toolbox." cols="35">


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Articles by Alex Swhear
Bon Iver, "i,i"
Central to it all is a Justin Vernon with an altered disposition, more confident and looser—at times, he even sounds content.
Thom Yorke, "Anima"
"Anima" goes to great lengths to differentiate itself from Radiohead's oeuvre.
Anderson .Paak, "Ventura"
Paak isn't making bad songs, but his adherence to formula is beginning to define him.
Iron & Wine, "Our Endless Numbered Days (Deluxe Edition)"
"Our Endless Numbered Days" houses many of the most elegant, striking songs of Sam Beam's career.
Girlpool, "What Chaos Is Imaginary"
While Girlpool's last album was sugary indie pop-punk, their new one paints in broader strokes.
Sharon Van Etten, "Remind Me Tomorrow"
It's a fascinating bridge from the moody indie pop of Van Etten's previous efforts to something a bit thornier, denser, more rewarding.
Mumford & Sons, "Delta"
There isn't a song here that couldn't soundtrack the movie trailer for some teen tearjerker.
Kurt Vile, "Bottle It In"
"Bottle It In"'s pace is unhurried, strutting to a destination without much concern for how long it takes to get there.
Noname, "Room 25"
The organic production has a real pulse to it, which gives the songs a spirited, fluid underpinning that feels uniquely suited to Noname's reserved but dexterous delivery.
Animal Collective, "Tangerine Reef"
The intentions here are environmentally noble, but the songs collectively feel like a minor mood piece rather than the cohesive statement the band aspires to.
Nicki Minaj, "Queen"
In a summer where scores of hip-hop heavyweights failed to whittle their work into a concise artistic statement, the sins of "Queen" are hardly glaring or unforgivable.
Christina Aguilera, "Liberation"
"Liberation" resurrects Xtina's considerable presence as a vocalist, though her attempts at navigating the modern pop landscape still verge on aimless.
Kids See Ghosts, "Kids See Ghosts"
While Kanye's lyrical performances are a marked improvement over his slapdash "ye" verses, "Kids See Ghosts" works best when he allows room for Cudi to shine.
Chvrches, "Love Is Dead"
"Love Is Dead" is saddled with a familiarity that's as limiting as it is endearing.
Beach House, "7"
"7" may be the most definitive—and enjoyable—break yet from the preconceptions of what a Beach House record should sound like.
Bonny Doon Are Who They're Supposed to Be
For their second full-length (and debut on Woodsist), the Detroit folk-rock quartet stopped thinking too much and just went to the beach instead.
Who Says There's No Leaving New York? A Report From The National's Homecoming Festival
More a family reunion for the Cincinnati-bred band than an actual festival, Homecoming was a wild party with occasionally tender moments.
Unknown Mortal Orchestra, "Sex & Food"
"Sex & Food" is at turns both understated and colorful, confident in what it wants to be but not afraid to wander into uncharted territory.


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Feet Are the Window to the Sole
There's something unassumingly intimate about feet.
Though it might be the obvious direction to take in this realm, I'm not talking about fetishization here. I have no personal sexual affinity towards feet that I know of.
I'm talking more about the messages can be conveyed simply by the way someone chooses to expose them or not, and their reasons behind that choice.
A lot of people seem to have very strong opinions about what is appropriate when it comes to foot etiquette. Sometimes, it's a simple matter of cultural norms — some parts of the world consider it massively disrespectful to not remove your shoes when entering a home or sacred space.
In most of the western world, however, this isn't the norm. Whether you choose to strip your socks or not can say a lot more about things even closer than home — about the depth of the relationship with your present company. For example, I have a friend who insists that being barefoot in anyone's home other than yours is a deeply intimate gesture and simply isn't done unless you are already sexually involved with that person.
Though I don't fully agree (because, given the option, I will choose barefoot and shoeless whenever possible), I can see what he's getting at. I expect my bed buddies to remove their socks when things get sexy.
I love the feeling of the earth on my feet and the sand between my toes. As a result, my feet get quite dirty quite easily, and quite often.
Usually, this isn't a problem. I'm very comfortable with the notion of mucking about with naked feet around other people. In fact, I rarely think anything of it.
That is until I'm exploring a new intimate relationship with someone I grow to care about… Then I became hyper-aware of the dust and detritus cushioning my steps.
What if you think I'm disgusting?
What if we end up in a jumbled position, with you between my legs, my feet in the air, and you take notice of my dirt-laden soles?
And what's worse – what if that turns you off?
I don't know much of anything about you yet, let alone how you feel about feet; for all I know, this could very well be a deal breaker for you. Where's your bathroom? I just need… Just give me moment, I'll be right back. (I really… really need to wash my feet as subtly as possible before I let you get too close, just in case.)
For something that makes me feel so free under other circumstances, this scenario brings me a little too much anxiety.
But since those earliest days, you have cracked me open. You have looked into me, through me, made me feel beyond what I thought would ever be possible again. You will never have any idea what it means to be to be here like this right now.
To lie exposed in a field, flashing my harness, wind aerating my hair, sprawled out just for you… I know you are always in awe of how readily I expose myself to you, to the world. But it hardly registers as a thing of boldness to me. It's in my nature.
But to be able to bare my sole, filth and all, without worry or care for your imagined dismay is something beyond my vocabulary. To be held so secure in my digital stance as you capture me in this vulnerable state, and for you to see beyond the darkness into everything else I want to give to you?
You have no idea how important this otherwise negligible gesture is for me to offer.
And that's how I know that we are sole mates.
The prompt image for this week was provided by Daddy's Little Monster and first published on Tumblr.
For more of what's heating up this week in Smutlandia, stroke this little logo right here.


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Friday, May 30 at 8pm, The Shepherd's crook presents:
Shelzee and the Sax Man, a two person band consisting of Mark Gravelle on saxophone and Michelle Emory on vocals and acoustic guitar.
The duo covers the likes of Lumineers, Mumford and Sons, Rihanna, Serena Ryder, Coldplay, and much more.
Fri, May 23, 8:00pm – 10:15pm. JACOB MOON CD RELEASE PARTY @ Roxy Coffee, 6 Mill St E., Acton
Jacob Moon has won acclaim for his songwriting, and counts artists such as Ron Sexsmith as fans of his work. He tours Canada, the US and Europe relentlessly, bringing his unique brand of one-man show to delighted audiences everywhere. For this special CD Release Tour, Moon will perform selections from 'Fascination', a record that, in part, pays tribute to his musical influences and includes some of his most popular interpretations by artists such as RUSH, YES and PETER GABRIEL.
"I took in his show a couple years ago at The Roxy and was moved by it"
Source of the Song is a magical experience — a listening room, lively sound, and the incredible talents of songwriters performing their own materials.
Friday, May 23rd @ 8 pm: "Evan Champagne takes an organic approach in fusing a variety of styles and instrumentation together with the acoustic guitar.
A multi-instrumentalist with truly signature vocals, he pushes things a step further with his artful use of live dub technology (aka: live looping).
Evan performs unique renditions of the hits and introspective original material, which he sells hundreds of copies of yearly, bootleg style, straight off stage. A live show is actually the only place you can purchase his hand-made album! "
"The Bistro's own Marena Manierka takes to the stage Saturday, May 24 at 8 pm with her gentle keyboard playing, perfect for Saturday night diners. Soft and subdued, Marena's music can be wonderfully paired with a night of conversation between friends in a classy venue".
"Friday, May 23 at 8 pm, The Bistro features Bob and Ian with a mix of covers from the 30's to today. Popular local musicians that keep things interesting with a wide selection of ballads and energy songs".
Blindfold Test will rock The McGibbon Hotel on Friday and Saturday nights, 9:30 p.m. to close. Top 40 music.
The McGibbon Hotel is located at 79 Main St. S., Georgetown. Info: 905-877-3388.
The Georgetown Choral Society is currently recruiting new members for the Fall 2014 session.
No special talents are required. Just a love of singing and a willingness to put in the rehearsal time.
Acceptance is subject to an audition with the Artistic Director.
Come and get a first-hand experience of being part of the choir by attending a rehearsal, held in the Christian Reformed Church at 11611 Trafalgar Road, Georgetown, every Monday evening at 7:30 pm.
If you are interested in joining the choir, contact Laurent Thibault (905 877 7795) or Alyson Arsenault (519-856-0016)
Short iPad video clip of Kev Morse from his performance May 15, 2014 at the Open Mic at The Bistro at Silvercreek.


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Machaba Ratombo Investments (Pty) Ltd is a level 1 BBBEE contributor founded in 2009 to facilitate investments in infrastructure development in Information Communication Technology (ICT) and Construction Industries.
Machaba Ratombo offers turnkey solutions and services in ICT and Construction. Based in Gauteng, the economic hub of South Africa, Machaba Ratombo is a fully empowered solutions provider and integrator. Beyond its core functions of sales, resource sourcing, project management, onsite support maintenance, training and business solutions, its role has grown enabled by its strategic partnerships to offer more complex turnkey solutions to the ICT and Construction sectors of the economy.


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Peterborough PE1 2PB
Tel: +44 845 0548035
Fax: +44 1733 440239
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LAND IN BULGARIA Aerial Pictures form Dolna Banya and Borovetc,Bulgaria
We have plots all across Bulgaria and we strive to present the plots in the best possible for the buyer format. Here are AERIAL pictures of Dolna Banya Valley, the ski resort of Borovec, the Ibar Golf Development where we have hundreds of plots for sale.
UNIQUE SEASIDE DEVELOPMENT of Log Villas in Bulgaria
Unique development in construction, location and facilities. The log villas come with 50 years guarantee and bring cosiness to this small development where the owners benefit form the picturesque location in close proximity to the sea and large array of equipment and possibilities for active holiday - riding, fishing and hunting amongst them.
NEW GOLF AND SKI Apartments, Bansko, Bulgaria
Located in South-Western Bulgaria near the Ski resort of Bansko and its nearby Golf Course this development is one of a kind. It boasts with more facilities than any other development and you will be pleasantly surprised by the prices.
The Borovets resort complex is the oldest and largest Bulgarian mountain resort. It is on the northern slopes of the Rila mountain, in the foothills of the tallest peak on the Balkan Peninsula Moussala /2925 m/. The distance between Sofia and Borovets is 65 km, a one-hour drive along a picturesque canyon above the river Iskar. Downtown Borovets is 1340 m above sea level, and the highest ski-tracks and facilities are at 2300 m.
The Semiramis Garden Apartment and Resort Complex lies at 1470 m above sea level, in a sunny and serene environment surrounded on all sides by pine forest, far /more than 2,5 km/ from the noisy Borovets downtown area and near ski tracks and facilities: the Yastrebets 2 and 3 ski tracks and facilities end right in front of the complex, and the lower station of the Yastrebets ski-lift, as well as the Yastrebets 1 track, are 250 m away.
Semiramis Garden of Borovets comprises four connected units: one of them is a five-star spa hotel with a restaurant, and the remaining three units are hotel rooms and apartments. The complex will be developed over 21 000 sq. m of land. The combined developed area of the buildings totals 21700 sq. m. The buildings are situated to the back of the plot, which leaves sufficient space to create a courtyard to the south with ample landscaping with alleys, children's corners and tennis courts. All apartments face south, southwest or south east, and all open on a magnificent mountain landscape.
The 5-star hotel section has 65 rooms, studios and suites, 24-hour reception desk, a lobby bar with an open fireplace, ski lockers, a conference room, shops and a restaurant seating 140.
The spa center has a swimming pool, sauna, Turkish bath, Russian bath, temperature-contrast pool, hot tub, whirlpool bath, Vichy bath, pearl tub, tanning beds, a medical cosmetics parlor, physiotherapy section, gym, four medical massage parlors and doctors' offices.
The apartment units include a two-level underground garage, a reception desk, lobby bar and ski lockers. Each unit is equipped with an independent luxury lift. All facades and public areas luxury finished using top-quality materials.
A total of 185 apartments of 35 to 120 sq. m will be put up for sale, of which:
- 38 two-bedroom apartments,
- 88 one-bedroom apartments,
- 59 studios.
The owners and tenants of apartments are allowed to use all hotel services and entertainment facilities.
Put into operation will be in November 2007.
Payment plan
- 50% - within 30 days after Preliminary agreement; - 50% - within 10 days after the receiving of the Permission for usage of the building.


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The portable glasshouse
In 1833, transporting living plants from England to Australia, was more difficult than transporting people.
The colony needed crops and vegetables, and seeds weren't always suitable. On the reverse trip, the mother country was also keen to be living specimens of the newly discovered flora, for display and for economic use.
There was sea spray on deck, no light in the cabins below, little fresh water and rarely a trained horticulturalist on board.
A few years back retired Professor of Landscape Architecture at University of NSW, Richard Clough, documented the critical voyage that proved there was a way to keep a plant alive for more than 100 days at sea.
Dr Nathaniel Bagshaw Ward was known for his studies of growing plants in glass containers, particularly so that delicate plants could be grow in the polluted atmospheres of cities like his own, London.
His big discovery was what we now call the Wardian Case, and its use on ships making the longest voyages possible at the time, to Australia and back.
The case was essentially a mini-glasshouse, but sealed to stop the loss of water and gases. What we would now call a Terrarium. Plants produce oxygen and carbon-dioxide and with the right mix of plant material, air and water, can survive for extended periods without any extra care or attention.
The crucial test voyage was from London to New Holland. Leaving London in July 1833, the schooner Persian arrived in Sydney (via Hobart) on New Year's Day 1834. After half a year at sea the plants in two Wardian Cases were landed at the botanic gardens, alive and well.
The acting superintendent at the time, John McLean (the boss, Richard Cunningham, had 'gone to New Zealand botanising'), repropagated the plants and they all seemed to survive. McLean then restocked the cases with new plants for the return voyage.
From summer in Australia, through minus six degrees at Cape Horn (where a foot of snow fell on the deck, and the cases) and a sizzling 49 degrees at the Equator, the plants arrived in London in great condition. Seeds of our local Black Wattle (Callicoma serrata) had germinated en route, all without being watered.
The record keeping wasn't great and we don't know what other plants travelled in these two trips, except that a coral fern, Gleichenia microphylla, was successfully introduced into a glasshouse in England, a plant previously only know from dried specimens such as those collected by Banks and Solander in 1770.
Image: Modern day Wardian cases from wardiancase.com. *This posting is from the Radio Archives (January 2008).


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Law enforcement officials are reporting that the Las Vegas mass murderer had no clear motive. That is ridiculous. His motive was plain as day – kill conservatives as inspired by leftist hate speech and other incitements.
Democrats, left-wing activists and the media are creating a smokescreen in the wake of the targeted political assassination of 58 "country" music fans on October 1. They are calling for more gun control when we already have 20,000 gun laws on the books.
Guns are not the problem, friends. Democrats are the problem but Democrats are using the subject of gun control to distract us from the real issues, which are these:
*Abuse of free speech rights: This is the biggest issue of all. The radical left, the media and Democrats have been seriously abusing "free speech" for more than two years now, even in major media sources.
They have been calling candidate Trump and president Trump and his supporters "nazis" and "fascists" and "white supremacists" and "racists". It never stops. Every day. It is reprehensible.
This extremist 'hate speech' is not your everyday angry speech that is protected under the Constitution. This speech has turned into pure incitement and it is directed at the radical fringe of the Democrat party, and extremists everywhere, i.e., people who are likely to commit violence like the Las Vegas killer did.
This is why more than 200 Trump supporters have been assaulted, and three murdered in the last two years; they have been intentionally targeted by militants on the left.
This is why the baseball-game shooter did what he did last June. He was a known socialist radical and a hothead who owned a high-powered rifle. He tried to kill a bunch of Republican congressmen since he believed that they were "nazis" and "racists" because he had heard that claim over and over.
This abuse of free speech appears to be what drove the Las Vegas killer to do his evil deed. He targeted a conservative audience of white "country" music fans who generally support president Trump, support the military and police, and sang God Bless America 90 minutes before the attack.
There is an old adage that "guns don't kill; people do". This means that no gun has ever hopped off of a shelf, aimed itself, and killed anyone. In short, it is people with evil motives who kill, sometimes using guns.
We don't need gun control; we need speech control, to restrain the violence-inciting speech of the left, and it needs to start with people like Obama and Hillary Clinton denouncing it. But they never will. Democrats privately embrace the violence that this speech is encouraging against Trump supporters.
Now here are other inspirations from the Democrat left that incited the Las Vegas killer:
*Evil atheism. There is no mention anywhere of the Las Vegas killer being a conservative Christian or believing in the goodness and perfection of God. Thus his actions would fit in with the Democrat agenda of hating Christians and hating God. We saw the result.
During the years that the killer was growing up in the 1960s and 1970s Christian prayer in school was being banned and Christianity itself was coming under an avalanche of ridicule and slander.
If the killer had been a good Christian he would not have done what he did.
He also was a gambler. Christianity sees compulsive gambling as yet another sin to be overcome. Gambling is an addiction, like drinking and drugs and sexual abuse, all of which are common on the left.
*Depression, anxiety: It is being reported that the killer was taking anti-anxiety medications that contributed to his mania. We know that anxiety and depression are common among Democrats and are a result of chaotic thinking that is encouraged by the left.
*The killer committed suicide rather than be captured alive: Suicide is common on the political left. It is a cowardly act, since bullies and thugs like the Las Vegas killer are also cowards.
*The killer's father was a bank robber, i.e., the killer had the genetic markers for an anti-establishment and even criminal culture that is reflected today in left-wing factions like violent antifa thugs, drug dealers, corrupt politicians, illegal immigrant criminals, muslim terrorists, labor unions, organized crime, etc.
On the other hand we conservatives are law-abiding and hard-working, we pay our taxes, go to church, are honest, serve in the military, respect the flag, etc.
*Liberals are pathological liars (like Hillary over her emails) and con artists (like ponzi schemer Bernie Madoff), and this killer was certainly one of them, having concealed his craziness and his evil plan for years. His Asian "girlfriend" should be questioned with polygraphs. There's much more to this female than meets the eye. Let's find out what she knows.
*Media violence: How many violent TV shows and movies did this killer watch over the years? These shows and films are all made by left-wingers in Hollywood. He could have seen thousands of gun murders in those shows, which deeply affected his psyche and de-sensitized him to violence and death.
*Security laxity: For decades Democrats have defamed our police, military, FBI, CIA, etc. This has led to deterioration in our personal and national security. Under a nominal security mindset somebody would have noticed the Las Vegas killer acting suspiciously somewhere along the line over many years.
It's like 9/11. There were many indicators that those terrorists were planning to attack us. If we had been vigilant 9/11 never would have happened. But even FBI turned a blind eye to repeated warning signs about the coming of 9/11.
*Political correctness: Some acquaintances over the years certainly must have known that the killer was crazy. He had been building up to Las Vegas for a long time and the attack was methodically planned and executed.
But those acquaintances might well have been loath to say anything to anyone for fear of being called 'judgmental', which is barred under political correctness.
Before political correctness reared its ugly head over the last few decades rational people could recognize evil behavior immediately. Today we are not even supposed to think that bizarre behavior is unusual under the guise of 'personal freedom', i.e., if that's what he wants to do, who am I to judge?
The Virginia Tech killer, for instance, was known as a lunatic on his campus but nobody did anything about him for fear that they would be seen as "judging" him and maybe even hurting his feelings. Instead 32 students died.
The Fort Hood terrorist was known as an extremist to US Army officials but they did nothing about him for fear of offending his muslim sensibilities.
*One report says that the Las Vegas killer had been registered as a Democrat in Florida in the 1980s. This would be no surprise whatsoever. The Pulse nightclub killer was a registered Democrat. The baseball player shooter was a Bernie Sanders supporter. And on and on.
*The killer's brother now has been arrested for child porn, which is a common evil on the Democrat left.
*Sexual violence: A prostitute has come forward describing the Las Vegas killer as obsessed with violent sex and rape fantasies. This comes out of the left-wing world of rampant sexual promiscuity, adultery, prostitution, pornography, sexual abuse and violence that has been flourishing in our culture since the 1960s. Famous Democrat sexual abusers include Bill Clinton, the Kennedys, Harvey Weinstein, many people in Hollywood, blacks, gays and millions of others in urban and liberal America.
This prostitute is just one example of someone who knew about this killer and who should have notified somebody about his behavior. There will be others, Nikitas3.com predicts, if law enforcement doesn't cover up this tragedy, which they very well may attempt to do.
The Las Vegas police department presides over a corrupt Democrat-controlled, union-controlled city. We cannot trust it. FBI may engage in a cover-up as well. We need an independent panel to look into this tragedy.
*Terrorism: The Las Vegas killer could well have fallen under the propaganda spell of America-hating terrorists. It is being reported that the killer's car had traces of one explosive, and 50 lbs. of another explosive, and that he may have been planning a car bombing.
The killer's many financial transactions are now being scrutinized for any direct ties to terrorism, although that may be moot. He may have acted as a self-financed terrorist himself.
Yet every time a muslim terrorist act is perpetrated against America Democrats like Obama seek to soften it, exonerate the terrorist, etc. and explain that America is really to blame. And thus the Las Vegas killer may have thought of himself as good, and that America deserved to be harmed. After all, he heard it from Obama.
(Please bookmark this website and send this article by e-mail to your friends. Please recommend this site to all of your friends via Facebook and any other means. Let's make Nikitas3.com the #1 conservative site by word of mouth. And if you would like to contribute to Nikitas3.com, please click the link at the upper right where it says "support this site". Thank you, Nikitas)


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North Indian, Chinese, Japanese
Holiday Inn Express & Suites, Gachibowli, Hyderabad
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WHAT!!!! "A SATURDAY DRUNCH" Tue, 23 August - Wed, 30 November · 11:25 am - 03:25 pm A Saturday Drunch, can you believe it? Following up from one of the best Sunday brunches in town, the team at Jonathan's Kitchen and Komatose have cur..


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Tutt Library Research Guides
See if Tutt Library subscribes to a journal by searching
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you'll be able to search within it to find articles.
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Nashville musician and educator Jen Gunderman divides her time between teaching, performing, and recording.
She has been at the Blair School of Music at Vanderbilt University since 2004, specializing in American popular music history courses, but she is also an active studio session musician and producer, and she plays keyboards and sings regularly with several groups based in Nashville, most often with Sheryl Crow.
In February 2016 she launched the Coursera MOOC (Massive Open Online Course) "Understanding the Music Business: What Is Music Worth?", which is the Blair School's first Coursera offering, and Vanderbilt's first Coursera course produced entirely in their Always Available format. She is also the host and director of the interview series Conversations at Blair, whose guests have included Peter Frampton and Sheryl Crow.
As a classical piano major at Vassar College, she studied at the Heidelberg-Mannheim Hochschule fur Musik and was elected to Phi Beta Kappa. After graduating, she spent two years working for the Artists & Repertoire Department at Columbia Records in NYC before moving to Seattle to earn an M.A. in ethnomusicology from the University of Washington.
For the next eight years she spent most of her time touring as a keyboardist/singer in the U.S., Canada, and Europe with various rock bands, including Dag (Columbia Records), the Jayhawks (American/Columbia Records), and Caitlin Cary (Yep Roc Records). Since then, she has worked as a freelance musician, performing and recording with such diverse musicians as Kris Kristofferson, Roger McGuinn (Byrds), Michael McDonald, Chris Robinson (Black Crowes), Exene Cervenka (X), Willie Nelson, Loretta Lynn, Todd Snider, The Dixie Chicks, St. Vincent (Annie Clark), John Prine, Emmylou Harris, Lyle Lovett, Travis Tritt, Jim Lauderdale, Vince Gill, Warren Haynes, Steve Cropper, Gretchen Wilson, Duane Eddy, Roseanne Cash, Brendan Benson, Sam Bush, Don Was, Robert Earl Keen, Patti Griffin, Buddy Miller, and many others.
She has performed at Avery Fisher Hall (Lincoln Center, NYC), Royal Albert Hall (London, UK), Tanglewood, the Hollywood Bowl, and the Ryman Auditorium, as well as in clubs, theaters, festivals, amphitheaters, and sports arenas. She has recorded for major and independent record labels and has appeared on radio and television shows in the U.S., Canada, and Europe, including Late Night with David Letterman, The Tonight Show with Jay Leno, The Colbert Report, The View, Good Morning America, and others.


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I found myself pondering what is the greatest gift you could give or receive? Now, depending on where you are coming from right now, there will many and varied answers.
Certainly, when I was young, I dreamed of becoming a famous singer. Later, I wanted the typical trinkets that appealed at that time. Fancy cars, fancy watches and of course a highly paid job.
The typical mid-life crisis was to cause me to seriously question what was I doing with my life. I was experiencing many trials and tribulations! I had tasted the addiction to gambling and alcohol with all of its serious ups and downs. I was following a path of looking for satisfaction in objects, which always only gave short-term satisfaction.
In my quest to discover who or what I am, I stumbled across on a book called 'A Course In Miracles'. This was eventually, to lead me to the Greatest Gift, it was to reveal to me through practical application over 365 lessons my true identity. I discovered I was powerful, not weak, I had no enemies and I could not suffer loss! Quite a statement.
What this did was to intensify my love for learning, which always had the same goal, to get to know our real nature, our real unshakeable Self. As we learn to move from skilled incompetence when it comes to knowing who we are, we discover naturally by simple short moments repeated many times until it is continuous, that we are pure consciousness. Not bound by descriptions.
We find HAPPINESS is our greatest gift.
Let us know what you think is your greatest gift!
If you are interested in finding out more about the practical steps you can take to discover your real nature and unlock the stranglehold that conventional duality has on those still captured by a false sense of self. There are many ways you can engage in this adventure.
Reach out – we are here for you.
Joe & Thomas


text: Tutorial: Miniature Art Supplies July 25, 2016 Manita Schaapman In this tutorial, Lili shows how to make these cute miniature art supplies. She'll make mini pencils, coloring pages, drawings and even a mini eraser. If you like this video, check out our other videos on this website!Follow our YouTube-channel and never miss an episode!Will you let us know in the comments how your art supplies turned out?


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Remember Me
Merry Christmas & Happy New Year
Wishing you all the best! Merry Christmas everybody!! It's Christmas Eve and it's almost time to open up presents.
1) Name at least one thing you got that you really love or you gave somebody.
2) Enjoy your glass of eggnog
Here are In House Rules and Expectations that help keep our In House Communityfun and competitive.
Currently, ourIn House Community is using KaKao Talk talk application to commicate in text live.


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This book is a journey into the culture of that most London of institutions, the Eel, Pie and Mash shop.
Despite claims to the contrary, London's traditional foods are Eels and Pie and mashed potatoes.
Eels, long a cheap and plentiful staple of London food for centuries were synonymous with this city, dominated and bisected by the River Thames. The first recorded eel and mash shop appears to have been Henry Blanchard's in Southwark in 1844 and Robert Cooke opened his first shop in Clerkenwell in 1862 - but it took an Italian immigrant Michael Manzi, a peasant from Ravello, to open the first eel empire starting with London's oldest remaining shop on Tower Bridge Road in 1891.
Manze's, Cooke's and subsequently Kelly's were in effect, the first self-defined working class restaurants selling food in clean and, importantly, respectable surroundings.
Today, these simple spaces hold within them the memories of a rich, largely undocumented cultural heritage of generations of working-class Londoners in a city whose only constant is change.
I grew up in East London in the 1970s, then a byword for poverty now a metaphor for gentrification. The streets then were navigated by pubs, rough, cheap cafes and eel, pie and mash shops. Often elaborately decorated with ornate Victorian tiling, many sold live eels in metal trays that faced the street to the fascination (and sometimes horror) of passersby. Inside, warmth and comfort. Steam. Tea. Laughter. Families.
Already in decline by the mid-century, the shops were still domintated by a handful of families and passed down through generations. By the turn of this century only an echo of former glories remained and today just a handful of traditional businesses operate. The decline of the eel (a "muscled icicle" as the poet Seamus Heaney has it in his 'A Lough Neagh Sequence') mirrors the sense of dislocation and fragmentation of traditional communities that the shops serve. Today's eel, pie and mash shops are havens for what the East End once was.
For someone like me who escaped the grey London skies to photograph and report from across the world, the shops represent some sort of consistency and a portal back to my own past. I first wrote about them in 2011 for a German magazine and this book is a tribute to both the extraordinarily hard-working owners and the loyal customers. It is also a way to gauge the change that has taken place since I left.
This book however, is no rosy description of the Cockney - that music hall, heart-of-gold caricature but an affectionate and serious look at what the East End and its people have evolved into.
Class remains resolutely with us, as deeply entrenched in Britian as it was fifty years ago: the working-class is sometimes demonised. Often ridiculed. Always taken for granted. This is where I've come from and I've tried to make as honest a picture as I could. The East End is a de facto multicultural melting pot – as it always has been - but it retains a singular pride and an energy - and, despite what the tabloids tell you, a welcome.
My grandparents would still recognise these shops. They would still eat there. With pleasure. Some things don't change.
The work is expansive: I've travelled to Lough Neagh in Northern Ireland to photograph eel fishing.
I've made work at both Barney's and Mick's Eels, the only two remaining companies that process the fish.
I've photographed and written about Millwall fans (who sing of the eel) and recorded those that now eat their pies and eels at home, too elderly and frail to journey to the shops.
Lastly, I have followed the bleed of the East End to its new spiritual home in Essex where Pie and Mash shops are undergoing something of an renaissance - identifying as they do with a re-imagined and distilled working-class culture that is geographically separate from their traditional roots.
The Englishman and the Eel is not an encyclopaedic record of every shop. Rather I've documented what I believe to be the most interesting and significant ones to make a book that I hope is a tribute to a timeless institution. I've used the eel as a metaphor and symbol of that cultural change: tenacious, rare - endangered - but still surviving.
This project – with your kind help by pre-ordering - will be published as a beautiful photo book by the most respected British photobook publisher - Dewi Lewis in late 2017. My last book with the same publisher – The Palaces of Memory - Tales from the Indian Coffee House, was runner-up for best Photography Book of the Year in America (Pictures of the Year International) in 2016 and made the American Photo Annual the same year. Stuart Smith, the internationally acclaimed book designer responsible for The Palaces of Memory (and countless others) will design The Englishman and the Eel. The journalist, broadcaster and author Michael Collins whose book, The Likes of Us: A Biography of the White Working Class - which won the George Orwell Prize, has generously agreed to write a piece to accompany my own words.
Risks and challenges
The publishing paradigm has changed - publishers now expect authors to significantly contribute to the funding of books so the obstacles are primarily financial. However, I learned a great deal from my last book, The Palaces of Memory. Again, I want this book to be the best it can be in terms of design and printing so all the funds raised (and some of my own money) will support the significant costs of producing this book. The work and the book design are complete so with your generous support this book will be printed in Italy and published by the end of 2017 to be dispatched in time for Christmas. There will be regular progress updates so that you can see how the process is moving forward.Learn about accountability on Kickstarter
Funding period
- (31 days)


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Data collection for the Southeast Florida Action Network (SEAFAN) to assess reef conditions before and during the 2014-2015 coral disease outbreak
Published Date:2016
Personal Authors:
Corporate Authors:
Description:"The Southeast Florida Action Network (SEAFAN) received numerous reports from citizens, scientists, and agency staff concerning the loss of tissue from multiple stony coral species, beginning in the fall of 2015 as the corals were recovering from a severe bleaching event the previous summer, and continuing into 2016. A study to comprehensively understand the extent, severity, and contributions of diverse environmental factors that may have led to this event was initiated by the Florida Department of Environmental Protection Coral Reef Conservation Program. Many sources of data about the marine environment and biota in the northern Florida Reef Tract (north of Biscayne National Park to St. Lucie Inlet) were identified by staff and members of the Southeast Florida Coral Reef Initiative's Technical Advisory Committee in April 2016. The period to be examined included the years 2012-2013 (when coral disease reports were minimal) and 2014-2015 (peak reporting years). Research assistants contacted data owners (agencies, scientists, nongovernmental organizations) and obtained datasets. Information about the data (metadata) was entered into a spreadsheet and data files were catalogued and archived for future access. In the future, multiple analyses may be performed by statisticians and epidemiologists to examine the conditions that might have led to the disease outbreak and to identify data gaps and monitoring needs that can improve the conservation of these valuable coral reefs"--Executive Summary.
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Sri Lanka's tourist arrivals during the year 2018 has registered a healthy growth of 10.3% reaching to 2,333,796 million tourists compared to 2,116,407 million tourist arrivals in 2017, according to official data released by the Sri Lanka Tourism Development Authority (SLTDA).
In terms of arrivals, March, February, June, and November recorded the highest growth rates while December recorded the highest number of arrivals of 253,169 for the year 2018.
"Although the tourist arrivals for the year 2018 fell slightly short due to the political instability we saw post October 26, I think in terms of earnings we have reached the Rs. 3.5 billion target," Minister of Tourism Development, John Amaratunga said. He also added that with Lonely Planet ranking Sri Lanka as the number one destination to travel in 2019 and the new promotional plans, he is optimistic Sri Lanka will receive four million tourists and generate an income of over $5 billion by the end of 2019. According to the Authority, India, China, the United Kingdom, and Germany continued to dominate as the top source markets to Sri Lanka in 2018, and a significant growth of arrivals was seen from Australia. In the South East Asia region, according to the UN World Tourism Organisation figures, in 2017, Thailand had over 35 million tourists, Japan 28 million, Singapore 14 million, Indonesia 13 million and Malaysia 26 million.


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Richmond Half Moon Zipper Pouch in Obsidian Brushstrokes Canvas
Richmond Half Moon Zipper Pouch in Obsidian Brushstrokes Canvas
The new I M P R I N T Collection, featuring beautiful textiles, colors and textures hand pieced to create unique works of art.
Versatile, handcrafted, fully lined small zippered pouch / purse. Perfect for organizing all the smallest items, such as cards, cash, keys, lipstick, etc. Easy to throw in your larger bag or slide into your pocket!
Made in a modern black brushstroke on white canvas print. It is fully lined in a solid cotton. YKK brass zipper closure and leather zipper pull. Shown with a BRASS BLACK ZIPPER.
Spot clean only.
Approximate sizes is 5.25" wide x 4.5" tall.
Please convo for custom orders or multiples.
Handmade with love in our Portland, Oregon studio.
NOTE: Some of the pictures have different prints than this listing. The first picture is representative of this listings print.


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100+ Head-Fier
- Occupation:
- Service writer for a garage
- Headphone Inventory:
Sony MDR-V7 (removable cord, beyerdynamic velour pads, damped)
Havi b3 pro (memory foam tips)
Monoprice 8320 (custom silicone molds, tape mod, defiltered)
Akg q701 (bass mod)
Fostex t50rp
Hifiman he400
Hifiman he500
Beyerdynamic dt880
Akg k701 or variant
- Headphone Amp Inventory:
Fiio e11k
Cmoy. Probably diy
Objective 2. Also diy
Ibasso dzero mk2
Fiio e6
Cayin c5
Jdslabs c5
Fiio e12diy
Toping nx1. Had one and it was a great amp but it had a bad channel
- Source Inventory:
Sansa Clip Zip 4gb in primetime purple. Rockboxed
Pretty pink iPod mini 128gb modded and rockboxed.
Ipod 3rd gen. Waiting on 256gb and massive battery.
A bunch of other iPods I've gathers over the
Ibasso dx90
Iriver hp100 series
- Cable Inventory:
Koss 3.5mm cable. This is a true giant killer cable, I'd expect to pay over $9000 for a cable this good. But I got it free off a set of broken koss computer speakers
Jds labs ultra short interconnect
Fiio l9 lod
Fiio l17 interconnect
Fiio l11 lod
- Audio-Related Tweaks:
- Mod all the things!
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Call Servoca Resourcing Solutions...
Being paid through an umbrella company is a hassle free way of working via an agency whilst allowing you to potentially maximise your take home pay compared to standard PAYE processing. When you join an umbrella company, you are considered an employed individual and the umbrella company will look after all of your Tax and National Insurance deductions, paying you on a weekly basis following submission of your timesheet to the agency, and any receipted expenses to the umbrella company.
Servoca Resourcing Solutions only work with a small number of umbrella companies who have been selected for the following reasons;
The sign up process is simple and takes about 5 minutes. You can contact them using the details provided below, and they will be happy to provide you with an accurate no-obligation illustration, which will allow you to get an idea, based on your rate and expected hours, of what your net pay will be each week. This illustration can be emailed to you and at this point, you can decide which one you would prefer to sign up with.
With the recent spate of umbrella companies that have fallen foul of HMRC good practice checks including several that major institutions such as the NHS will not allow any contract workers to be engaged through, it is important that the umbrella companies that our contractors use are considered absolutely minimum risk for the good of clients and contractors alike.
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It's all in the family as you're welcomed into Chef Emeril and Alden's New Orleans home for a dynamite dinner not soon to be forgotten! As you become Chef Emeril's newest sous chef for the evening, assist in preparing a family style meal of the Gulf Coast's finest cuisine. If you pay close attention, you may even pick up some of his culinary secrets! After putting the final touches on the dishes, you and five of your lucky friends will gather around the Lagasse family table to taste the fruits of your labor. But what shall you pour? Leave that to Emeril Lagasse Foundation board member and legendary winemaker Dan Kosta who will be joining in the fun. Dan and Alden will open their latest pinots from AldenAlli, a collaboration between the Lagasse and Kosta families. At the table, Dan will also finally open the rare five liter of Kosta Browne's "2011 Wine of the Year" as rated by Wine Spectator. The bottle, described as "in 2009 the greatest vintage yet for California Pinot," was crafted by Dan and comprises fruit from three vineyards: Gap's Crown, Terra de Promissio and Walala Vineyard. Dan created this custom-etched bottle when he was Carnivale du Vin's 2011 Honorary Bacchus. It features Alex Beard's iconic "Ole Leggi" image from the inaugural year of Boudin, Bourbon & Beer.
5L Kosta Browne Sonoma Coast Pinot Noir 2009
Donated by Alden & Emeril Lagasse and Dan Kosta


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The threat of a security breach has never been more real that it is today.
Our wide range of cyber-security capabilities, technologies and our expert advice helps you navigate the complexity whilst securing your business from loss of data and reputation.
Technical Drive are ISO 27001 certified and are also a certified Cyber Security partner so once again you can be sure you are safe in our hands.
Our security services include:
Security Best Practice assessments
Firewalls and Intrusion Prevention
Endpoint Security
Anti-Ransomware Security
Advanced Malware Protection
Email and Web Security
Anti-Spam Protection


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Level Up for Students is a 32 week teacher facilitated, classroom primarily based character education and social emotional finding out system for elementary, middle college and higher school students designed to minimize school failure and dropout price by enhancing school achievement, discipline, motivation and benefits. Our full day plan has efficiently improved college climate in hundreds of schools across the country by making an organized, protected, and healthy playground where all students are engaged and active. All that is required is a wide spread understanding of how mostly essential and simple early reading expertise delivered are and the fact that they are crucial financial foundations along with education foundations. In 1993 the playground at Seattle's Gatzert Elementary School, a high-poverty college exactly where a third of the youngsters are homeless, resembled a battlefield at lunch recess. A. Now is the time for new income, and, a remedy to capacity that moves the public schools to proficiency with a 100{3670b4763785d66d203c7eb01b8d240860c51771324336656fa2c770df6a3fa3} very first items initial delivery of Early Reading Capabilities. KOI Education offers expert improvement packages primarily based on the Blueprint from the National Center on Constructive Behavioral Interventions and Supports (PBIS).
In reality, the individual gift providing networks (Ultimate Character Networks), giving early literacy to the poorest of the poor, developed as extensions of the public schools, will deliver the wiggle room" needed in turnaround budgets. These efforts, Your Atmosphere president William Donofrio told Education Globe, instill in students the belief that they are loved and valued by the neighborhood as a entire and help them understand that the neighborhood has a stake in their accomplishment in college and in life.
If this situation continues and with no the continued service of counselors on campus, schools need to discover alternate methods to present and conduct character education programs and workshops for their students. Due to the fact students devote so a lot time in school, our schools offer a critically crucial opportunity to guarantee that all students get the help and help they need to have to reach their complete potential. In the end, researchers located no proof that the applications, taken individually or collectively, improved students' behavior, academic performance or gains, or their perceptions of the college climate.
The I Care" Positive Parenting Character Curriculum addresses parental involvement, character development, and community involvement. As children are denied assistance of character education teachers or counselors at school, most of them are not even acquiring simple morals and virtues becoming taught even at home. Our society has in no way ready 100{3670b4763785d66d203c7eb01b8d240860c51771324336656fa2c770df6a3fa3} of the youngsters in urban places to start off kindergarten ready-to-read.
This belief in America, initially heavily populated by Protestant immigrants, creates a circumstance of a-priori assumption that humans are morally deficient by nature and that preemptive measures are needed to develop young children into acceptable members of society: property, church and school. The Theory of Constraints (quick book) by Eliyahu M. Goldratt -1990 goes the whole distance to explain how to set the difficulty and the resolution at the level (college district) to influence the expectations of our communities. The neighborhood and its schools and governments pay me back with a monetized return from the ROI savings getting discussed. Teachers who are assisting out their students by conducting such applications must actively participate instead of just being a passive bystander.


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Sotheby's International Realty Canada
Built in 2011 by Menkes, Lifetime Developments, Lumiere Condos stands 32 storeys high with 357 suites. Conveniently located in the Bay Street Corridor at College Street and Bay Street, Lumiere Condos is at 770 Bay Street, Toronto. Click here for Real-Time listings, floor plans, prices for sale and rent in Lumiere Condos, updated daily.
Trevor Fontaine | Sales Representative | Sr. Vice President, Sales
Sotheby's International Realty Canada, Brokerage
email@example.com | 416-476-7117
Copyright © 2019 | trevorfontaine.com | All Rights Reserved
Sotheby's International Realty Canada is Independently Owned And Operated.
Buy - Sell - Invest


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Get disease updates, inspection results, health news and much more with our weekly e‑mail newsletter
JACKSON, Miss. - Today the Mississippi State Department of Health (MSDH) reports one new human case of West Nile virus in Hinds County, bringing the state's total to 15 for 2011.
So far this year, cases have been reported in Coahoma, Forrest (2), Hinds (3), Jones (3), Pearl River (4), Tallahatchie, and Wayne counties. A previously reported Marion County case was removed due to additional testing. One death has been reported in Jones County.
In 2010, Mississippi had eight WNV cases and no deaths.
Mississippians are encouraged to take appropriate precautions to reduce the risk of contracting WNV and other mosquito-borne illnesses year-round: remove sources of standing water, especially after rainfall; if you will be in mosquito-prone areas, wear protective clothing (such as long-sleeved shirts and pants) during peak times from dusk until dawn; and use a recommended mosquito repellent according to manufacturer's directions.
Symptoms of WNV infection are often mild and may include fever, headache, nausea, vomiting, a rash, muscle weakness or swollen lymph nodes. In a small number of cases, infection can result in encephalitis or meningitis, which can lead to paralysis, coma and possibly death.
For more information on WNV and other mosquito-borne illnesses, a checklist to reduce the mosquito population in and around homes, and a brochure on WNV, visit the MSDH website at www.HealthyMS.com/westnile or call the WNV toll-free hotline from 8 a.m. until 5 p.m. Monday through Friday at 1-877-WST-NILE (1-877-978-6453).
Press Contact: MSDH Office of Communications, (601) 576-7667
Note to media: After hours or during emergencies, call 1-866-HLTHY4U (1-866-458-4948)


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News, News and More News!
Good afternoon everyone! The Missouri Society of Radiologic Technologists Board of Directors met this summer and again about a week ago. During this time, several key items were discussed and were fine tuned and are now ready to be announced and released to the membership.
We are changing our membership service to a new platform called Memberplanet. This will be a significant cost savings for us as well as give us the opportunity to offer additional features later down the road. By now, all current members should have received an email asking you to update your info. Please do this, so we can make sure we stay in contact with you moving forward. You can find our new membership login page HERE.
Speaking of membership, it was also previously announced that the MoSRT will be doing away with the Graduate Bridge membership. All students that join the MoSRT before they graduate will get two years of active membership upon expiration of their student membership (December 31 of their graduating year). This gives the students the opportunity to buy their discounted MoSRT Annual Conference tickets without having to buy the previously available Graduate Bridge membership. If you have any questions regarding your current membership status, please do not hesitate to email firstname.lastname@example.com or email@example.com.
All Conference Competition Rules and applications are now live, including our new Scientific Display Rules and Application, and can be found by clicking HONORS, SCHOLARSHIPS, & AWARDS in the navigation bar at the top of the page and selecting the competition you are interested in. If you have any questions or need any assistance, please do not hesitate to email me at firstname.lastname@example.com.
Lastly, you might have noticed a change to the home page for the MoSRT website. We are sporting a brand new blog for the home page, to make formatting our announcements and messages easier. This will also enable me to allow individuals on the Board to post their own updates to the site if they become so inclined.
Thank you very much for your time and as always, if you have any questions, comments, or concerns, please do not hesitate to reach out to any MoSRT Board member. You can find the list of our positions by clicking ABOUT US in the navigation bar at the top of the page and clicking BOARD OF DIRECTORS.
Have a great week!


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We had some keen gardeners join us today. They are getting their new gardens ready for planting. Reeve and Isaac even managed to plant some lettuces and tomatoes with Mum helping.
Check out how the Butterfly Garden is growing. Search the Swan Plants for caterpillars when you come to visit. I wonder when we will see our first butterfly hatch?
A catterpillar of a very different size has appeared in our garden. It was on the plan but I think our 'Secret Helpers' have been hard at work! We have to design some antennae and eyes for this amazing creature. Do you have any ideas?


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The Mark C. Studenic Memorial Scholarship
The Mark C. Studenic Scholarship was established by the Marietta Morning Rotary Club in May 2009 for the purpose of providing annual merit based scholarships to Washington County residents pursuing a post-secondary degree in Engineering or Engineering Technology. The award is for $500 and is renewable for up to three years, provided that the student maintains a 3.0 GPA. The scholarship was established to honor the life and work of Mark C. Studenic.
Mark was a graduate of Copley High School, Class of 1980, and the University of Akron in 1985 with a Bachelor of Science degree in Mechanical Engineering where he was a member of Lamda Chi Alpha. He was employed by American Electric Power, Muskingum River Plant, where he held various positions until March, 2007, when he was appointed Plant Manager. He was a member of Marietta Morning Rotary Club, where he was a former president. He was a strong leader and devoted son, husband and father, always putting his family first. He had many hobbies including gardening, golf, camping, playing cards, the outdoors and animals. He loved is family and friends and was a devoted Rotarian. It was because of his dedication to the Morning Rotary Club and the community that this scholarship was established.
The application for the scholarship is available through the Marietta Community Foundation. You can access the scholarship page of their website at http://www.mcfohio.org/scholarships. Applications are also provided to all Washington County High Schools or can be picked up at the Marietta Community Foundation office located at 100 Putnam Street, in downtown Marietta.To download an application, click here.
Past Recipients of the Mark C. Studenic Scholarship include:
2018: Kellar Windland, Belpre High School
2017: Kaylee Pate, Warren High School
2016: Abbie Ashbaugh, Marietta High School
2015: Zach Robinson, Marietta High School
2014: Justin Warner, Marietta High School
2013: Caden Brooker, Fort Frye High School
2012: Kaitlin Pottmeyer, Waterford High School
2011: Matthew Klinger, Fort Frye High School


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Show my name on the attendees list for events I am attending: Yes
Swift Secrets In Cube World FR gratuit - Updated <center> <img src="http://www.gry-online.pl/galeria/gry13/346314871.jpg" /> </center> The model of Beijing Olympic complex is built by a Lego Club in Hong Kong. Studies on adults who engage in memory exercises and games have shown a marked decrease in brain metabolism in the area of the brain directly linked to working memory and other cognitive functions, suggesting that they were using their brains more efficiently. The Zome System is used in thousands of schools worldwide – elementary through college – and by leading scientists, mathem
Design quotient
What are (DQ) Points?
DQ points are a measure of your contributions, they correspond to how active you are in the Research, Ideas and Evaluation phases of a challenge.


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According to the Centers for Disease Control and Prevention's most recent survey, approximately 32.9 percent of women living in California have been victims of violence, sexual violence, or stalking by their partner or spouse.
If you have been the victim of domestic violence and have child, you may be concerned about your partner's custody rights once you have separated.
How is custody decided if there is domestic violence?
The first thing that will happen is that the judge overseeing the case must decide if there is domestic violence.
If the violence took place in the last five years, the judge will treat the case as domestic violence if at least one of two conditions is met. Either one parent must have been convicted of domestic violence against the other parent, or any other court has decided that one parent has committed violence against the other parent or the children.
If the violence occurred more than five years ago, the judge has the option of taking that into consideration when determining custody. If the court reaches the conclusion that domestic violence has been committed, custody will not be granted to the abuser. However, that parent may receive visitation rights.
Is it possible for a parent that has committed domestic violence to receive custody?
Yes, it is possible for a judge to grant joint or sole custody to the abusive parent.
First, it must be proved that it is in the child's best interest to be placed with that parent. Also, the parent must have successfully completed a 52-week batterer's intervention program as well as any other court ordered courses or counseling programs. In addition, the parent must also be in compliance with any terms of probation, parole, or restraining orders. Most importantly, the parent must not have committed any additional acts of domestic violence.
Will my partner receive visitation rights?
It is possible for the individual that committed domestic violence to receive visitation rights.
If a protective order or other type of restraining order has been issued, the court will consider if it is in the best interest of the child to have either unsupervised visitation or supervised visitation with the parent. Depending on the severity of the situation, it is possible that the court may decide that visitation is not an option and deny it altogether.
Is it possible for the grandparents to receive visitation rights?
Yes, it is possible for grandparents to be granted visitation, regardless of whether the parents of the child are married or unmarried. However, it is up to the grandparents to prove that such visitation is in the best interest of the child. Visitation rights of the grandparents may be denied if both parents agree that visitation should not be granted or if the parent with sole legal and physical custody does not allow it. In such cases, it is the grandparents' responsibility to convince the judge otherwise and prove that visitation is in the child's best interests.
If you have been the victim of domestic abuse and have a child, it is important to know your options concerning custody rights. For advice in such cases, contact an attorney experienced in family law.


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|Relationship status - I'm being stalked by
three eighties superstars
Tuesday, 8 March 2011
Rehumanize Yourself
1 comment:
I try not to spend too much time on Facebook. I feel like it just dumbs down my IQ.ReplyDelete
I have to tell you, you hit the nail on the head. However, to go along with the song lyric poster, I might also add the passive aggressive comment poster.
"You lied to me for the last time, you broke my heart, and now you've lost my trust. Call me if you ever decide to grow up and be a MAN."
First off, we all know who you're talking about, especially when your page says "IS IN A RELATIONSHIP WITH JOHN Q SMITH." Second off, why not tell him this to his face instead of telling him on Facebook? Which brings me to the third point, why would you want to air your dirty laundry on Facebook?
I feel like I was better off not knowing that the girl I sat next to in 2nd grade has a husband with a gambling problem who once cheated on her with a bartender on a cruise ship.


text: Every morning when I walk outside I look up. My mind gives it's weather evaluation of what's happening. Sometimes I'm met with bald blue skies and harsh sunlight; sometimes beautiful clouds float magically overhead, and sometimes I get an eyeful of rain. I get a little smile on my face when I see wispy paths of white, or puffy balls of fluffy cotton floating in the morning light. Sometimes it's like a motion picture that I could lie on my back and watch for hours. The scene below happened a few weeks ago while I was trying to make a different photograph. I looked up and the sky above me was amazing. The subtle reflections of light through the oncoming storm clouds were mesmerizing, and I thought this picture was even better than what I was trying to capture in front of me.