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|By PR Newswire
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|January 5, 2014 07:02 PM EST
HATFIELD, England, January 6, 2014 /PRNewswire/ --
Halaven® (eribulin) has received reimbursement approval in the Czech Republic as a highly innovative drug for patients with metastatic breast cancer, effective from the 1 January 2014. Eribulin is the first, single-agent chemotherapy to demonstrate a prolonged overall survival in patients with heavily pre-treated advanced breast cancer, compared to other single agent chemotherapies.[1]
"The reimbursement of eribulin in the Czech Republic is an important step forward for women with metastatic breast cancer," says Professor MUDr. Bohuslav Melichar, PhD, the Scientific Secretary of the Czech Society for Oncology. "These patients urgently need new treatment options and in particular, therapies which have demonstrated an overall survival benefit in heavily pre-treated patients. The advent of eribulin will be welcomed by patients and doctors across the country."
Breast cancer is the most common cancer in Czech women and accounts for nearly 25% of all newly diagnosed malignancies in the female population.[2] More than 6,400 people are diagnosed with breast cancer each year in the Czech Republic[3] and metastatic disease will develop in approximately 30% of cases.
"Metastatic breast cancer continues to affect many women across Europe. We are pleased that the Czech health authorities recognise the innovative drug status and clinical value eribulin may offer to women with locally advanced or metastatic breast cancer," commented MUDr, Miloš Živanský, Medical Director of CEE in Eisai. "The reimbursement in the Czech Republic underscores the potential importance of this treatment and Eisai will work closely with local health authorities to ensure that women in the Czech Republic have rapid access to a treatment that has a proven overall survival benefit."
Eribulin received European Commission approval on 17 March 2011 based on the results of the pivotal Phase III EMBRACE (Eisai Metastatic Breast Cancer Study Assessing Treatment of Physician's Choice (TPC) Versus Eribulin E7389) study.Eribulin is now available in 50 countries worldwide.
In the EMBRACE study population (n=762), eribulin was shown to prolong overall survival in heavily pre-treated patients with metastatic breast cancer by 2.5 months compared to patients receiving Treatment of Physicians Choice (TPC), representing a mix of real-life treatment choices (eribulin 13.1 months vs. TPC 10.6 months, HR 0.81 (95% CI 0.66, 0.99) p=0.041).[4] Updated data confirmed that patients treated with eribulin survived a median of 2.7 months longer than patients who received treatment of physician's choice (overall survival of 13.2 months versus 10.5 months, respectively, HR 0.81 (95% CI 0.067, 0.96), nominal p=0.014).[4]A pre-planned analysis of patients from Region 1 of the study (North America/Western Europe/Australia) showed a significant overall survival benefit of eribulin over TPC of 3.0 months (p=0.009).[4]
The most commonly reported adverse reactions among patients treated with eribulin were asthenia (fatigue), neutropenia, alopecia (hair loss), peripheral neuropathy (numbness and tingling in arms and legs), nausea and constipation.[4]
Eisai is committed to developing and delivering highly beneficial new treatments to help improve the lives of people with cancer. Built on scientific expertise, Eisai is supported by a global capability to conduct discovery and preclinical research, and develop small molecules, therapeutic vaccines, and biologic and supportive care agents for cancer across multiple indications.
Notes to Editors
Halaven® (eribulin)
Eribulin is a non-taxane, microtubule dynamics inhibitor indicated for the treatment of patients with breast cancer who have previously received at least two chemotherapeutic regimens for metastatic disease and whose prior therapy should have included an anthracycline and a taxane.Eribulin belongs to a class of antineoplastic agents, the halichondrins, which are natural products, isolated from the marine sponge Halichondria okadai. It is believed to work by inhibiting the growth phase of microtubule dynamics without affecting the shortening phase and sequesters tubulin into non-productive aggregates.
Global Phase III Clinical Study 305 (EMBRACE)[4]
EMBRACE (Eisai Metastatic Breast Cancer Study Assessing Treatment of Physician's Choice (TPC) Versus Eribulin E7389) was an open-label, randomised, global, multi-centre, parallel two-arm study designed to compare overall survival in patients treated with eribulin versus a Treatment of Physician's Choice (TPC) arm. TPC was defined as any single-agent chemotherapy, hormonal treatment or biologic therapy approved for the treatment of cancer; or palliative treatment or radiotherapy administered according to local practice. The study included 762 patients with metastatic breast cancer who previously had been treated with at least two and a maximum of five prior chemotherapies, including an anthracycline and a taxane. The vast majority (96%) of patients in the TPC arm received chemotherapy.
In the total Phase III EMBRACE study population, eribulin was shown to prolong median overall survival in heavily pre-treated patients with metastatic breast cancer compared to patients receiving TPC by 2.7 months (13.2 vs 10.5 HR 0.81 (95% CI 0.067, 0.96) nominal p=0.014). A pre-planned analysis of patients from Region 1 of the study (North America/Western Europe/Australia) showed a significant median overall survival benefit of eribulin over TPC of 3.0 months (nominal p=0.031).
The most commonly reported adverse reactions among patients treated with eribulin in the EMBRACE study were fatigue (asthenia), a decrease in infection-fighting white blood cells (neutropaenia), hair loss (alopecia), numbness and tingling in arms and legs (peripheral neuropathy), nausea and constipation. Peripheral neuropathy was the most common adverse event leading to discontinuation from eribulin, occurring in less than 5% of the patients involved in the EMBRACE trial. Neutropaenia only led to eribulin discontinuation for 0.6% patients. Death due to serious side effects, discontinuation and dose interruptions to treatment were lower in the eribulin arm of the trial compared with the TPC arm.
Metastatic Breast Cancer
Over 300,000 women are diagnosed with breast cancer in Europe every year, of whom about one third subsequently develop metastatic disease.[5],[6]Metastatic disease is an advanced stage of the disease that occurs when cancer spreads beyond the breast to other parts of the body.
About Eisai
Eisai is one of the world's leading research and development (R&D) based pharmaceutical companies and we define our corporate mission as "giving first thought to patients and their families and to increasing the benefits health care provides," which we call human health care (hhc).
Eisai concentrates its R&D activities in three key areas:
- Oncology including: anticancer therapies; tumour regression, tumour suppression, antibodies, etc.
- Neuroscience, including: Alzheimer's disease, epilepsy, pain and weight loss
- Vascular/Immunological reaction including: thrombocytopenia, rheumatoid arthritis, psoriasis, inflammatory bowel disease
With operations in the U.S., Asia, Europe and its domestic home market of Japan, Eisai employs more than 10,000 people worldwide. From its EMEA Knowledge Centre in Hatfield, UK, Eisai has recently expanded its business operations to include Europe, the Middle East, Africa, Russia and Oceania (EMEA). Eisai EMEA has sales and marketing operations in over 20 markets, including the United Kingdom, France, Germany, Italy, Spain, Switzerland, Sweden, Ireland, Austria, Denmark, Finland, Norway, Portugal, Czech Republic, Slovakia, the Netherlands, Belgium, Luxembourg, Russia and the Middle East.
For further information please visit our web site http://www.eisai.co.uk
1. SPC Halaven (updated August 2013). Available at: http://www.medicines.org.uk/emc/medicine/24382. Last accessed October 2013
2. Epidemiology of breast cancer in the Czech Republic. Mamo.cz. http://www.mamo.cz/index-en.php?pg=professionals--breast-cancer-epidemiology Last accessed November 2013
3. Globocan 2008 statistics http://globocan.iarc.fr/factsheet.asp Last accessed October 2013
4. Cortes J, O'Shaughnessy J, Loesch D, et al. Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study. The Lancet. 2011; 377: 914 -923
5. World Health Organization. Atlas of Health in Europe. 2003. World Health Organization, Regional Office of Europe, Copenhagen, Denmark.
6. Cancer Research UK. Breast cancer incidence statistics. http://www.cancerresearchuk.org/cancer-info/cancerstats/types/breast/incidence/#world [http://www.cancerresearchuk.org/cancer-info/cancerstats/types/breast/incidence ]. Last accessed November 2013.
Date of preparation: December 2013
Job code: Halaven-UK0227
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Is it common to get clot of white lump after tampon removal ?
today i removed tampon and a large lump of white flesh fell out. i am on the pill. this wasn t a blood clot. what is it?
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Welcome to Healthcare Magic Forum
This kind of dischrge from the
is seen in a miscarriage/abortion. You should visit a gynaecologist for an examination. If it was an
incomplete abortion
, it has to be complete, as there may be some mass remaining in the uterus.
Answered: Wed, 16 Mar 2011
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Welcome to Healthcare Magic Forum
This kind of dischrge from the uterus is seen in a miscarriage/abortion. You should visit a gynaecologist for an examination. If it was an incomplete abortion , it has to be complete, as there may be some mass remaining in the uterus.
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The private social network Yammer just released a pretty cool feature called 'Praises.'
Praises are basically badges that you can give a coworker for an accomplishment, similar to the ones foursquare, GetGlue and others offer.
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Pad Thai Noodle Kit
Retail Price:
Our Price: $2.45 (Save 28%)
Why You'll Love It
About This Brand
Noodle: Rice, Water, Sauce: Sugar, Tomato, Water, Rice Vinegar, Fish Sauce (Anchovy, Salt, Water), Garlic Chives, Pickled Radish (Radish, Salt, Water), Soybean Oil, Garlic, Onion, Modified Corn Starch, Tamarind Paste (Tartaric Acid, Succinic Acid, Malic Acid, Tamarind Seed Gum, Pectin), Citric Acid, Chili Pepper, Xanthan Gum
California residents: Learn more on Prop 65 warning. Disclaimer: Information, statements, and reviews regarding products have not been evaluated by the Food and Drug Administration. Results vary person to person, and there is no guarantee of specific results. Thrive Market assumes no liability for inaccuracies or misstatements about products.
Amount Per Serving
Why You'll Love Pad Thai Noodle Kit
With so many different types of cuisine, there's no reason to get bored with your next meal. Thai cooking brings exotic flavors and healthy dishes to the table every time, creating delicious meals that are uniquely their own. If you're striving to make the perfect Thai dish, now you can with Thai Kitchen Pad Thai Noodle Kit. There's no need to head out and find this authentic dish when you can make it right at home and have it taste just like the real deal.
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Why you should consider Thai Kitchen Pad Thai Noodle KitThere aren't many dishes that have the same flavor profile and warmth as Pad Thai. The dish itself combines sweet, nutty, and slightly spicy flavors to create a meal that is truly unlike anything else out there. Thai Kitchen Pad Thai Noodle Kit is an excellent way to enjoy this exotic dish in the comfort of your own home and is a great change of pace from your regular go-to recipes. Check out some of the reasons why you should consider these delicious hearty noodles the next time you're feeling like pasta:
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Thai Kitchen is serious about two things—making the most authentic food possible and making sure that it's easy to create. For those looking for quick ways to have a great meal, Thai Kitchen Pad Thai Noodles is well worth looking at.
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The Pad Thai Noodle Kit is a great way to experience the sweet, nutty flavors of Thailand, however, it's only one of several great products that the company offers. No matter what your taste buds are craving—sweet, savory, spicy, or something in between—Thai Kitchen has plenty of great dishes and condiments available. Check out a handful of them below:
Thai Kitchen Thai Peanut Noodle Cart
With a rich roasted peanut sauce and 100 percent rice noodles, this easy to make noodle cart is ready in just 4 minutes and is filled with flavor. It's a great way to get an unmistakable Thai dining experience without any hassle.
Thai Kitchen Organic Coconut Milk
From curries to sautés, coconut milk plays a prominent role in a variety of Thai dishes. This coconut milk is made from 100 percent organic ingredients and is as nutritious as it is delicious, ensuring the best product possible no matter how it's being used.
Thai Kitchen Red Curry Paste
This curry paste combines fresh red chili peppers with lemongrass and Thai ginger. It's perfect for use in curries, stir fry recipes, or even as a base for soup. It can also be used to marinade meats and vegetables before cooking, and is entirely organic and GMO free.
Thai Kitchen Green Curry Paste
This paste is similar to the red curry paste Thai Kitchen offers, only with the use of milder green chili peppers instead of red ones. It adds a touch of spice to any recipe, and can be used for stir fries, curries, soups, and much more.
Thai Kitchen Premium Fish Sauce
Fish sauce is a key ingredient in a huge range of Thai dishes as well as many other Asian and Pacific style foods. Thai Kitchen uses only the first pressing of salted anchovies to make this premium fish sauce, making it great for cooking and used in place of soy sauce.
Reviews For Pad Thai Noodle Kit
Based on 22 Reviews
I love the sauce and the kit is really convenient. I didn't realize it wasn't a microwave meal at first, but it is super yummy, especially if you add meat and veggies!
- Evan
Quick & yummy
I liked this meal kit....only wish is that there was more sauce. It was easy to make and very tasty.
Leftovers were not that great...I think what sauce there was absorbed totally into the noodles.
I'll buy it again though. :)
- Linda
Tasty and Easy to Use
This is quite nice. I confess, I used without chicken as I was on my own at the time and didn't want to cook. I will use this product again.
- Marlene
Quick Dinner
I love this kit because you can add whatever vegetables or protein you have and make it a complete meal.
- Kirsten
Pad Tai
Not bad at all, could use more flavor and mild spices.
- Karena
I purchase atleat two at a time
This is such a easy, quick and delicious at home pad thai kit. My grocery store sells it for almost double the Thrive Market price. I love to top this with ground peanuts and chives.
- Jessica
patty rath
very good with meat or chicken you can have a meal.
- patty rath
Better than I thought
My kids even liked it. Simple, easy to make.
- Happy mama
Pad Thai Noodles
The noodles had a very good flavor, but they took longer to cook than the recipe stated.
- Karen Paul
Taste wonderful
- Loretta
Not bad
This kit is quick and easy but the sauce was too sweet for my taste. It wasnt bad but i wont order again.
- Carolina
A new dish
I have never tried this before, and it was easy and tasty. I will add more vegetables next time!
- Genevieve
Tai noodle kit
Loved the product! However this exactly relates to my frustration when I tried to find it to order more!!
- Pat
Pad Thai Noddle Kit
I enjoy this product, easy to prepare and overall quite yummy!
- Lyn
my go-to meal when I don't feel like cooking. Tasty and satisfying.
- kathy
Maybe Better Without the Sauce
Although the noodles are sufficiently thick, the included 'sauce' with these noodles makes them very sweet tasting and unappealing to me. Maybe a better score rating (and tastier result) can be achieved without the sauce.
- Abdul-Raheem
This stuff is really good and good for you. I love that so many companies are coming out with wonderful gluten free options. While this is a little salty, it still tastes great.
I tend to add some Tyson GF chicken nuggets to this when I make it. It's all quick and easy to make.
- Alicia Burrough
No cholesterol
I have been trying really hard to cut back on cholesterol and I love that I found these. I love to eat Asian and Thai. This kit makes it quick and easy to get your favorite meals done right in your own kitchen.
I was amazed to see that Thrive Market had these and I will continue to purchase them here.
- Leda S
Noodles Great, Sauce Not So Much
Because I need to eat gluten free, I started experimenting with different types of non-gluten noodles and pasta. The brown rice pasta is wonderful, but the corn noodles are not very tasty at all. Then I discovered pan Thai noodles. They are different, but in a good way.
After signing up for Thrive, I decided to purchase Thai Kitchen Pan Thai noodles. I really enjoyed these noodles before. However, I had never used the kit with the sauce before. I was not impressed with the sauce, but I will purchase the noodles again next time.
- Katrina Nunez
Good for quick meals
This is a great kit to use when I don't have a lot of time to whip up a meal, but I still want something healthy. I'll usually have some chicken breast with it, or add lean cuts of beef. It also works with shrimp, but my family aren't big seafood people, so that doesn't happen very often. It has that signature Pad Thai sweetness and tang. I also sprinkle chopped nuts into the mix to get the full experience.
- Alora G.
Like at the restaurant
I love Pad Thai, it's my favorite Thai dish, right up there with green curry. This is a great approximation of what the restaurant serves, and I just add chicken breast to make a delicious, aromatic meal that has a real authentic Thai flavor and that just sweet enough taste that makes Pad Thai so sweet and savory. I wish it had slightly less sodium, but the sugar is all derived from natural cane, so there's no sweeteners added to this mix.
- Alton Guerrero
Makes It Easy
I'm short on time and effort after a long day at work, and this stuff helps me make delicious pad thai noodles without all of the effort of fully preparing each ingredient. It's not perfect, and it's not as good as a sit-down restaurant, but at the same time, it's still very good, and it's something I'd enjoy eating on a regular basis (and I do eat on a regular basis). Don't expect restaurant-quality, but do expect an easy and yummy way to make pad thai.
- Darren Y.
Featured on Thrive Market
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22 December 2012 11:14 AM, PST | TVSeriesFinale.com | See recent TVSeriesFinale news »
Negotiations reportedly came down to the wire but How I Met Your Mother is now set to be renewed for a ninth and final season.
The current eighth season is the last under CBS' license deal and the contracts with Himym creators Craig Thomas and Carter Bays and the cast are set to expire as well. Himym is the network's fourth-highest rated sitcom and has stood up to tough Monday night competition, particularly from NBC's The Voice. CBS clearly wanted to keep the show going if possible.
The producers, Josh Radnor, Cobie Smulders, Neil Patrick Harris and Alyson Hannigan were apparently all willing to return for a ninth season but Jason Segel was not. His movie career has really taken off, had been talking about leaving for awhile, and he'd already spent eight years on Himym.
According to Deadline, »
- TVSeriesFinale.com
Similar News Items"How I Met Your Mother" (2005)
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Jason Segel
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- Rooney Mara And Jason Segel Don't Find Much Life In 'The Discovery' [Review] (From The Playlist. 20 January 2017, 10:30 PM, PST)
- Sundance Review: 'The Discovery' is a Thrilling, Emotional Search for Life After Death (From The Film Stage. 20 January 2017, 10:24 PM, PST)


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World-shaking thriller "Bourne" series was released 01 in the latest episode. The central character of Jason Bourne, played by Hollywood actor Matt Damon. Not long passed any new pictures coming out of the audience thought that Matt Damon was.
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by Meedo
published on 2012-09-12
Keywords: scene, object, elevator,
by Chris MacDonald
published on 2009-12-09
Keywords: plant, flower, leaf, model,
Blending 3D and Photography - Chapter 1
by Andrzej Sykut
published on 2013-07-26
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by Carl Ahearne
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Features of This Trackacoustic sonority
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These are just a few of the hundreds of attributes cataloged for this track by the Music Genome Project.show more
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Jake's Alien Adventures
Written by Noel Gordon, Sonia McCalla
Illustrated by
Lovereading4kids Price £7.19
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As soon as this book is back in stock we will send you an email.Compare book price We'd love you to buy your books from Lovereading - especially if we helped you to choose them! But as our mantra is guidance, and that includes guidance on price, please do use our 'Compare Book Price' service to discover if the best value deal is from Lovereading or another specialist bookstore.
Jake's Alien Adventures by Noel Gordon, Sonia McCallaJake has a toothache and cannot play outside with his friends as he has taken some medicine. His sad dream of not having anyone to play with is caught by the dreamcatcher above his bed and sent to planet Venus, where Woo Woo lives. Woo Woo receives the dream cloud with his aerial and reads Jake's sad dream - so he jumps into his spaceship and flies across the Milky Way to Earth. Jake is excited and happy to see Woo Woo's spaceship hovering outside his bedroom window. Woo Woo plays with Jake's fluffy hair in amazement - he has never seen hair before! Woo Woo invites Jake to his home. They fly across the Milky Way to Venus. Jake is having the time of his life and cannot believe that all the plants and birds are blue - even Woo Woo's home is blue and floats above the ground! Jake and Woo Woo have both found special friends for life. When Jake is sad or lonely, Woo Woo comes and plays with him. Woo Woo really likes Earth because of all the different children and the many different languages. Jake's Alien Adventures will appeal to young children aged from 4-7 years old and contains beautiful full-colour illustrations. The book was inspired by my 5 year old boy who was having problems sleeping, says Noel behind his motivation to write the book.
About the Author
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Book Info
32 pages
Interest Age: From 4 To 7
Noel Gordon, Sonia McCalla
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Marketing management and strategy
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November 29, 2016
How the sales cycle has changed in the wake of inbound marketing
HubSpot CEO Brian Halligan recently outlined research on how the sales cycle has changed: Supply is up, demand is down and the cold call is dead.
November 01, 2016
How Dunkin' Brands brought one-to-one marketing from hype to reality
Dunkin' Brands has long built a name through traditional advertising. But it wanted to personalize marketing with one-to-one marketing methods.
July 18, 2016
Companies sidle up to customers with marketing personalization
Salesforce Marketing Cloud is helping companies inch closer to customers, particularly with tactics like marketing personalization.
June 27, 2016
LinkedIn purchase may signal new era of open APIs
Microsoft's LinkedIn purchase may open up APIs and enable new competitors to take advantage of the treasure trove of social CRM data in LinkedIn.
Marketing management and strategy Get Started
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agile marketing
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account-based marketing (ABM)
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Demandbase moves account-based marketing forward
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Manage Marketing management and strategy
Learn to apply best practices and optimize your operations.
Why you should care about Agile marketing
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Four ways to create the ultimate personalized customer experience
As the demand for a more personalized customer experience grows, companies are scrambling to adapt. Follow these four tips to succeed with customer engagement. Continue Reading
Data analytics strategies and tools incite positive customer journeys
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Five common pitfalls in content marketing strategies
Companies still need to be convinced that content marketing strategies are must-haves in the marketing toolkit. Continue Reading
Communication essential to sales and marketing alignment
A lack of communication between sales and marketing teams can derail internal processes. Here's how to ensure collaboration between the two factions. Continue Reading


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Tomas Barfod
Salton Sea
Fear of Friends
Aug 01, 2012 Web Exclusive
Producer and drummer Tomas Barfod's latest collection of organically-infused minimal techno tracks is full of unfulfilled potential. Pulsating opener "D.S.O.Y." has a relentless drive, but its arpeggiated synth lines rarely morph into new guises, while previously EP-released "Came to Party," with its repetitive android voices ("Everybody/Everybody/Everybody/Came to party," they chant) also suffers from an arduously unchanging dirty groove. As a consequence, these tracks are too limited in scope, too wallpaper thin to have any enduring impact. There are some exceptions: the subtle change in pace midway through "Ecstesizing" helps keep things relatively fresh, as do delicate production touches: the glitchy, skipped-record interlude of "Don't Under" adds some much-needed variety.
Unfortunately Salton Sea neither has the ideas or innovation to be engrossing electronic music in its own right, nor the momentum or dramatic thunder to fill the dance floors. While inoffensive, Barfod's work here ultimately fails to really engage. (www.tomasbarfod.com)
Author rating: 5.5/10
Average reader rating: 4/10
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Series: Ecological Studies Volume: 212
By: M Bredemeier, S Cohen, D.L. Godbold, E Lode, V Pichler and P Schleppi
The protective function of forests for water quality and water-related hazards, as well as adequate water supplies for forest ecosystems in Europe, are potentially at risk due to changing climate and changing land-management practices. Water budgets of forest ecosystems are heavily dependent on climate and forest structure. The latter is determined by the management measures applied in the forestry sector. Various developments of forest management strategies, imposed on a background of changing climate, are considered in assessing the overall future of forest-water interactions in Europe.
Synthesizing recent research on the interactions of forest management and the water regime of forests in Europe and beyond, the book makes an important contribution to the ongoing dialogue between scientists dealing with different scales of forest-water interactions. This collaborative endeavour, which covers geographic and climatic gradients from Iceland to Israel and from southern Spain to Estonia and Finland, was made possible through the COST Action "Forest Management and the Water Cycle (FORMAN)", which was launched in 2007 (http://www.forestandwater.eu/).
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'Glee' 3.15 Preview Teases the Aftermath of the Car Crash
To tide fans over the April return of "Glee", FOX has debuted a new preview for the upcoming outing. Picking up right after the last episode left off, it will deal with the aftermath of the accident involving Quinn.
The sneak peek video hints that there will be a lot of tears seen in the episode with Rachel regretting how things have turned out. "It's not right. I'm so, so sorry," she says, while Mike is featured comforting a crying Tina.
While Quinn's fate remains unclear, a set photo which was taken during the filming of the show's new episode in February saw the former cheerleader on a wheelchair.
The answer to the burning question will be revealed in "Big Brother", which is set to air Tuesday, April 10 at 8 P.M. ET on FOX. The episode will also mark Matthew Bomer's debut appearance as Blaine's older brother.
Following the airing of the said episode, BIO Channel will premiere a special dedicated to the musical series at 9 P.M. ET.
- Watch Barden Bellas Dance in 'Pitch Perfect 3' Behind-the-Scenes Video
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- Future Enjoys Lavish Getaway in Dubai in New Video for 'Poppin' Tags'
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+44 1803 865913
By: Charles A Platt
172 pages, 73 b/w photos
Reissue of a late 19th century book describing the work of the great garden designer, Charles A Platt (1861-1933). Beautifully illustrated.
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Aiseesoft Mac Blu-ray Player is used to play Blu-ray disc, Blu-ray folder and Blu-ray ISO image files with high qualified image and sound. And users can freely choose the specific Blu-ray title/chapter to play. Moreover, users can enjoy any video/audio files on this player, such as MPG, MPEG, VOB, MP4, RMVB, MKV, AVI, FLV, SWF, MOD, TOD, AAC, AC3, MP3, OGG, WAV, WMA and so on. Key Features: 1.Play any Blu-ray disc, Blu-ray folder and Blu-ray ISO image files Adopting the most advanced technology, this player can not only play Blu-ray disc, but also can play Blu-ray folder and Blu-ray ISO image files at high quality. 2.Play general video This Mac Blu-ray Player is capable of playing all popular video/audio files, like MPG, MPEG, VOB, MP4, RMVB, MKV, AVI, FLV, SWF, MOD, TOD, AAC, AC3, MP3, OGG, WAV, WMA, etc. It now can also play 4K video with best quality. 3.Offer outstanding HD video enjoyment This software can bring a big audio-visual feast to users. With it, it is never a dream to enjoy the am ...
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Headless Zombie 4.0
It is a story about a former nobleman called Carl, who converted into a zombie. Carl is trying to sort things out in his difficult situation and become a human again, but keeps losing his head again and again. Physical platformer with a twist, juicy noir graphics and amazing animation. Awesome storyline, tricky puzzles. Finish the story and find out what realy happened with Carl.
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Little Aqua World 4.9
The game takes you through an amazing and dangerous world of one-celled organisms. To complete a level your character is to collect all the green balls - food. Other organisms also are fighting to survive, and with them you'd better not mess with. Some cells live a simple life and they do not care about you. Others, on the contrary and strive to eat a neighbor. Therefore, to replenish your health, you can collect blue balls - vitamins.
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Mission Escape From Island 3 2.1
Mission: Escape from Island 3 - a new episode of great shooter with amazing graphics! Unexpected continuation of the story of the past episode, upgraded graphics, new enemies and weapons, more diverse levels and wonderful effects will not leave you indifferent! Find out what happened on this strange island, where you find yourself. Good luck and enjoy the game!
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Tower Defence Warriors Outpost 3.9
Tower Defence Warriors Outpost game is the best way feel the warriors' spirit! Start playing this amazing game and get into wonderful world of medieval kingdoms, castles and villages, thrones, skirmish, defence tower, dungeon, crusader, defence war, onslaught, defence heroes, fury and invasion! Do you remember movies about crusader, castle defence or defence tower heroes or another medieval community? Do you want to get to the same medieval empir
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Holiday Champagne Screensaver 1.0
You have not seen this screensaver probably yet! Amazing holiday screensaver. For all the people who love atmosphere of the holiday, Christmas and New Year. To create a festive mood! All of this you will find in our new Holiday Champagne Screensaver. Free holiday screensaver will decorate your desktop. It can be installed in anticipation of the holiday, and can simply treat yourself with no reason. Champagne screensaver will please you every day.
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Kings Game Clash Or Defense 2.8
Exciting casual strategy for Castle Siege fans! If you want to get into the spirit of the war, the game "King's game: Clash or Defense" is the best option for you. Start playing this amazing game and get into the wonderful world of medieval kingdoms, castles and villages, shootings, dungeons, characters, and the violent intrusion. Do you remember the movie about medieval communities? You want to get into the Middle Ages, to become king and watch
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Block Topia 2.1
BlockTopia is a game about building amazing things and exploring the world. You have over 50 blocks and a dozens of decorations to work with, as well as various terrain and climate types. Build huts, castles and palaces to realize your great ideas! You are a God in this game, so do what you want and have fun! Click the right mouse button to place blocks and the left mouse button to destroy them. Press TAB to open inventory.
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Aiseesoft Blu-ray Player 6.5.30
Aiseesoft Blu-ray Player can help users play Blu-ray disc, Blu-ray folder, ISO files, popular videos, including MPG, MPEG, MPEG2, VOB, DAT, MP4, M4V, TS, MTS, M2TS, MXF, WMV, RM, RMVB, ASF, MKV, AVI, 3GP, 3G2, F4V, FLV, SWF, MPV, MOD, TOD, QT, MOV, DV, DIF, MJPG, MJPEG, TP, TRP, WebM, HD video, with the perfect video quality. It is reliable and expert in playing Blu-ray discs released in different regions and dates trough simple clicks of mouse. Plus, after updated, it has been newly added playback menu of Blu-ray files. Key Functions 1.Support playing any Blu-ray disc, Blu-ray folder and ISO files Aiseesoft Blu-ray Player can easily play any Blu-ray disc/DVD, Blu-ray folder and ISO image file. It is able to play Blu-ray discs chapter by chapter or title by title, and it allows to freely choose their preferred language, video quality, audio quality, audio effect, subtitles etc. 2.Compatible with various video files Besides playing Blu-ray files, it can play popular media files like MPG, MPEG, MPEG ...
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Balance Game Ultimate 2.6
Amazing arcade game to test your dexterity and reaction. Roll the ball, pass the obstacles and collect bonuses! Stylish graphics and interesting gameplay will not leave you indifferent.
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Falco Corners 7.1
This 3D game can be played as a stand-alone game, over the Internet.Features: 1. 3 Levels of smart engine power. 2. Playing via Internet or local Network. 3. Amazing 3D OpenGL Graphics and Animation. 4. Music and Sound effects. 5. Undo/Redo.
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Shift Em Mania 1.2
Shift'em Mania is an amazing and fun turn-based tactical ball game. Your objective is to get your color balls to the bottom of a maze. Well, it's not quite as simple as it looks like. The level is filled with ramps, walls, black holes and your opponent doesn't give an easy time. Block your opponent by pushing your color balls into strategic positions to stop him from doing the same to you. Use walls to your advantage and collect bonus score. Thin
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Mission Escape From Island 2 2.1
Mission: Escape from Island 2 - a sequel of the great shooter with amazing graphics! At this time, you expect more exciting plot twists, the crowds of menacing enemies and huge levels in the dangerous jungles of the island! Can you overcome all obstacles and be saved? Use weapons wisely, think over your actions, and you will do it. Good luck!
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Grind Zone 3.9
GrindZone - an amazing place where there are unexpected adventures, cute atmosphere and intense battles. Cute cartoon style of game will like to fans of the soft colors, anime fans and all those who are tired of playing with pseudo-realistic graphics. GrindZone - place for a very wide opportunities. Here, as in any self-respecting RPG, there is leveling, and various skills, and shops, mobs, loot, bosses, in general, everything is what millions of
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Falco Bautrix 8.0
Tetris-like game with a touch of match-3. Be clever while collecting hearts of the same colors. Nice music and amazing graphics give you a complete sense of fulfillment. Three levels of difficulty, ergonomic interface. Tasteful execution of an old classic!
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Turkey Shoot Swamp Gobble 3.5
Turkey Shoot Swamp Gobble app will certainly put you in good spirits and inspire with a new energy! If you want to become a turkey killer, if you are fling about blast and hunt for wild bird, learn everything about turkey hunting and shooting effects, then welcome to the most amazing turkey shoot game! This Turkey Shoot Swamp Gobble game is not just shooting game it is big game hunting bird. Moreover it is the turkey shoot game free! So don't lo
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Tipard M2TS Converter 7.1.82
Tipard M2TS Converter not only enables you to convert M2TS to HD MKV, HD H.264, HD AVI, HD TS, HD WMV, HD MPEG 4, HD MOV and other 1080p HD videos, but also can convert M2TS to general video formats like MP4, MKV, WMV, AVI, MOV, M4V and more. Meanwhile, it can also convert M2TS to common audio formats including MP3, FLAC, AAC and so on. Besides, you can edit your video by trimming, cropping, adding watermark to your video. Moreover, it supports English/French/German/Japanese four interface languages. It is compatible with windows 10. Key Functions: 1. Convert M2TS to MP4, MKV and more This M2TS to MKV software is able to convert MTS/ TS to 1080p HD videos like HD MKV, HD H.264, HD AVI, HD TS, HD WMV, HD MPEG 4, HD MOV and so on. Meanwhile, it can convert your video to MP4, MKV, WMV, AVI, MOV, M4V and other general video formats. 2. Edit your video according to your needs Tipard M2TS Video Converter can help you to edit the video effect by adjusting the Brightness, Saturation, Contrast, Hue and Volume ...
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Julias Quest 4.2
Travel around the UK with Julia and solve the mystery of her grandfather's old diary in Julia's Quest: United Kingdom! Journey through amazing British cities and other places of interest in this fantastic Match 3 game. Learn interesting facts and unlock incredible bonuses as you solve puzzles to place in the diary. Can you unravel the hidden message left behind by Julia's grandfather? -Awesome gameplay -Fast-paced fun -Travel around the UK!
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Miners Strike 2.1
Being a miner is one of the most dangerous occupations in the world. However, in this game we are not talking about the mines or their living beings. Immerse yourself in this amazing adventure with an exciting game of match three. Try to complete all 7 levels! Nice music and beautiful graphics will make you come back to this game again and again. Have fun!
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Sem 3.5
Plunge into the dark atmosphere of a cave and see how nimble you can be. Five amazing levels await, each growing more difficult and spooky. You are a white mage, a child who can shape shift at will so you can jump tens of meters. And you have the ability to control light, and direct the light energy from the legs and accelerate yourself or you even create a shield of light that will destroy your enemies. Your mission is to escape from the cave,
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Tipard 3D Converter 6.1.46
Tipard 3D Converter is composed of three converting parts: 3D video to 2D video, 2D video to 3D video, and 3D video to 3D video. It not only convert 2D video like MP4, MOV, M4V, MKV, AVI, WMV and more to 3D video on Mac, but also it allows you to convert 3D videos to 2D video and other 3D modes with amazing conversion speed. This Tipard 3D Converter software also has the ability of editing effect. It supports various devices like iPhone 6s/ 6s Plus, iPhone 6/ 6 Plus, iPad Air 2, iPad mini 4/3, iPod, etc. Key functions: 1. Convert 2D video to 3D video Tipard 3D Converter has the ability of converting 2D video to 3D video. It supports any video format like MP4, MKV, AVI, WMV, MOV, M4V, TS and more. It also highly supports HD videos, such as TS, M2TS, HD MPG, HD MPEG, HD MPEG2, HD MPEG4, HD MP4, HD WMV, and so on. 2. Convert 3D video to 3D video Tipard 3D Converter supports many 3D formats like Anaglyph 3D, Side by Side (Half-Width) 3D, Side by Side (Full) 3D, Top and Bottom (Half-Height) 3D and Top an ...
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Business Down During Weanling Portion of New Zealand Mixed Sale
The weanling portion of New Zealand Bloodstock's national mixed sale ended on Monday with downturns from the previous year. The 226 weanlings sold grossed $2,033,250 (approximately $923,096 in U.S. funds) and averaged $7,644 ($3,470). In 2001, the gross and average established sale records for weanlings of $2,149,500 and $9,596, respectively.The top price of $90,000 ($40,860) was brought by a Carnegie filly produced from Australian group III winner Solop Performance. The filly is a half-sister to Australian group II winner Solo Show and Australian stakes winner Clout. New Zealand Bloodstock purchased the filly on the behalf of an Australian client.The clearance rate reached a very healthy level of 81%, the same selling rate as last year.Following the weanling portion, the sale continued with yearlings, 2-year-olds, untried stock, racehorses, and the first of the broodmares being offered.The top-priced yearling price an $18,000 ($8,172) gelding by Kashani out of Blue Waltz. He was purchased by New Zealand Bloodstock as agent for a Malaysian client.Top price among the 2-year-olds was the $13,000 ($5,902), given by Neville Atkins of Auckland a gelding by Groom Dancer--Lady Paree gelding. Among untried stock, a King's Theatre --Track Appeal filly fetched the top price of $7,000 ($3,178) from Greg Marcus of Australia.The top-priced racehorse was Centennial, a stakes-winning daughter of Centaine who was purchased by Kieran Moore Bloodstock for $16,000 ($7,264).The first 60 of the 325 broodmares catalogued were offered. The top price was the $48,000 ($21,792) given by Endeavour Capital for Amber Ace, who was stakes-placed as a 2-year-old. .Her first foal is a colt by Cape Cross and she was sold in foal to O' Reilly.
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text:
On the Street from October 2001
What are your plans for Halloween?
Wednesday, October 31
Since the anthrax scares, have you been double-checking your mail?
Tuesday, October 30
What is your favorite Halloween candy?
Monday, October 29
What is your costume for Halloween?
Sunday, October 28
Does the new anti-terrorism law unreasonably encroach upon our civil liberties?
Saturday, October 27
How can Americans combat the rising cost of education?
Friday, October 26
How would you rule in the O.J. Simpson road rage trial?
Thursday, October 25
Should Kansas expand its health-care coverage?
Wednesday, October 24
Should Terry Allen be worried about his job?
Tuesday, October 23
Which do you prefer: 'City of the Arts' or 'The Art of a City'?
Monday, October 22
Where do you generally park for KU football games?
Sunday, October 21
How will KU match up against Missouri?
Saturday, October 20
Is America overreacting to the anthrax scares?
Friday, October 19
With Sprint laying off 6,000 jobs, are you worried about your own job?
Thursday, October 18
Should the South Lawrence Trafficway be constructed through Baker Wetlands or south of the Wakarusa River?
Wednesday, October 17
What do you like best about fall?
Tuesday, October 16
Is America prepared for bioterrorism?
Monday, October 15
Are you concerned about terrorist retaliation?
Sunday, October 14
How will the new parking garage help Lawrence?
Saturday, October 13
What are the odds that KU will win its homecoming game?
Friday, October 12
Is America doing enough to aid the Afghan refugees?
Thursday, October 11
With the war on terrorism started, do you fear for your safety?
Tuesday, October 9
Do you think Osama bin Laden is in Afghanistan?
Monday, October 8
Are you worried about bioterrorism?
Saturday, October 6
Are two "big box" stores too many?
Friday, October 5
The city of Lawrence fines motorists $50 when their music can be heard from 50 feet away. Is this appropriate?
Thursday, October 4
Legislators have voted to split Lawrence into two congressional districts. Was there a better option?
Wednesday, October 3
Are you comfortable with the U.S. joining forces with Afghan rebels and Russians?
Tuesday, October 2
What do you think about having the Kansas Speedway so close to Lawrence?
Monday, October 1
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I love watching YouTube and Daily Motion Videos. Check out this program that pays you to view and share these videos on your social networks - http://trckrs.com/121124/
ClixSense Works
Mar 19th 2011 at 1:56 AM
Clixsense is a Paid to Click (PTC) site that has been around for some years. The concept is very simple - click on an ad, view it and get paid cash. 1 cent per click for most ads. Doesn't sound much you may say, but build a team and get a cut of their eaenings and you see the power of referral marketing.
There is also an addictive game called ClixGrid where you can earn cash.
All up I highly recommend this site which has just had a major facelift. It gets a Dr Kelp 5 star rating.
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Bulgarian Banks Increase Their Profit In 2013
Finance » Be a reporter: Write and send your article Expats.bg All Are Welcome! Join Now!
Transactions of Bulgarian banks registered a net profit of BGN 586.8 M in 2013.
This means an increase of BGN 17.64 M compared to the previous year, as the website Money.bg has informed.
Gains are up 3.1%, with most of this result generated by 23 out of 30 banks, which declared a joint total revenue of BGN 665.73 M for last year.
Seven banks have finished 2013 at a loss, compared to nine in 2012.
- » State Debt Decreases in EU, Bulgaria in Q3 2016
- » Bulgaria Posts 46.4% Drop in FDI in Jan-Nov 2016
- » BSE: Six New Companies Join SEE Link Indices
- » Airplane Tickets Prices Up by 28.6% in December
- » Bulgaria's Stock Exchange Reports BGN 5 M More in Turnover for 2016
- » Debt of 12 Bulgarian Municipalities Increases by 500%
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Joe Rogan and Brendan Schaub discuss Cris Cyborg's potential UFC Anti-Doping Violation and the likelihood that she wasn't doping.
Actress Meryl Streep denounced Donald Trump at the Golden Globe Awards, taking a sideswipe at MMA in the process. Dana White blasted back.
UFC Fight Night Countdown: Rodriguez vs. Penn takes you inside the gyms of two featherweights preparing for a main event between old school and new
Dana White to fighters: "Ride the thing out and become a free agent, but honor your deal. I have to honor my deals."
While UFC bantamweight champion Amanda Nunes feels a strong national pride in her home country of Brazil, the United States changed her life.
Professional athletes wield more influence than some of them realize. They're heroes to an impressionable youth, but aren't always role models.
Check out former two-division UFC champion BJ Penn's Hall of Fame speech from July of 2015. He returns to the Octagon at UFC Phoenix
2016 had its fair share of knockout finishes in the UFC, and heavyweight champion Stipe Miocic's UFC 203 knockout of Alistair Overeem made the top
Watch Joe Lauzon defeat Diego Sanchez at UFC 200. Lauzon takes on Marcin Held in the co-main event at UFC Fight Night 103 in Phoenix.
UFC bantamweight champion Cody Garbrandt says former teammate and former titleholder TJ Dillashaw was never a world champion.
UFC Fight Night 108, which is slated for March 18 in London, has landed a battle between two Top 10 light heavyweights.
Jon Jones believes that Ronda Rousey will always be an "absolute legend." That's not to say that he agrees with those that think she should
Despite the UFC announcing a new opponent for Jimmie Rivera for the upcoming UFC Fight Night Phoenix, Rivera on Saturday said that he is not
Coming off of the biggest victory of her career, it will be a while before we see UFC bantamweight Raquel Pennington back in the Octagon.
2016 had its fair share of knockout finishes in the UFC. Some were more stunning than others, but Mark Hunt's KO of Frank Mir
After two decades, Mike Goldberg is no longer manning the mic for the UFC. He issued a farewell statement late Friday night.
UFC Fight Night 103: Yair Rodriguez vs BJ Penn fight card at the Talking Stick Resort Arena in Phoenix on January 15, 2017.
Fifth-ranked bantamweight Bryan Caraway details the injury that forced him out of his scheduled bout at next week's UFC Fight Night 103 in Phoenix.
Third-ranked UFC middleweight Ronaldo "Jacare" Souza finally has a fight.
Former UFC lightweight champion Rafael dos Anjos is done with the 155-pound division.
Mauricio "Shogun" Rua is set to face Gian Villante on his home turf when the UFC returns to Brazil in March.
With back-to-back losses, Ronda Rousey is at a crossroads and many believe she needs to make big changes, including former UFC welterweight champ Matt Serra.
Ronda Rousey's coach, Edmond Tarverdyan, prior to his charge's fight at UFC 193, laid out his philosophy on coaching.
Mark Hunt is tired of fighting cheaters, but he can't afford not to, so he's ready to take matters into his own hands.
Former UFC women's bantamweight champion Miesha Tate underwent successful nose surgery on Wednesday to 'straighten that very curvy septum.'
Amanda Nunes' coach and former UFC featherweight Din Thomas believes Ronda Rousey avoided the media before UFC 207 because she was embarrassed.
An injury has scrapped a pivotal UFC Phoenix bantamweight match-up, but John Dodson is offering to step in to save the day.
UFC champ Amanda Nunes was emphatic in her response when asked whether or not Ronda Rousey is overrated as a fighter.
When almost everyone is clamoring for a title shot, why in the world did Jessica Andrade turn one down when the UFC offered?
UFC women's bantamweight champion Amanda Nunes got very animated with company president Dana White after she crushed Ronda Rousey. What did she say?