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P: RiRi
M: Preggo Bell
B: Olsen
I would go through SJP for those 3 and Upton.ReplyCancel
Gabby no. Upton rent girl chic.
Looks like Maggie gylenhal. Found Kims leftover drapes that went with kins sofa.
Posh looked like the cover of Vogue USA
Riri wins
bwahahaha Kate Upton looks like she is wearing a Halloween costume…ReplyCancel
Victoria is really making a name for herself in the fashion world, still not ALIST but very nice, luv what rihanna is wearingReplyCancel
WTH is Kate Upton wearing?ReplyCancel
Red on a red carpet is not dramatic, it just blends in.
RiRi does look good, but could've worn that any where,ReplyCancel
Gabriel Union looks like cross between a hula dancers and one of those little crocheted dolls that used to cover my grandmother's toilet paper rolls. Why why why? She's a beautiful woman. Kill your stylist, Gabrielle.
Posh's dress is lovely. Wish I could afford to buy her clothing line. Makeup is awful, though – as @sugarbread says, she looks like KK looked on the cover of Vogue, with eye makeup like a a Bulgarian wrestler.ReplyCancel
Now here are the costumes!
Love Posh's look and even her pose.
Rhianna's surly look – she's made that they wouldn't let Cara hold her.
Oh dear, Maggie G, I love you but that dress looks like my gran's scrapbooking paper.
You go, SJP!ReplyCancel
They have been fighting a while now because Peter supposedly kept begging jakeypoo. To get him work and Maggie told Peter to get it himself! Way harsh Tai!ReplyCancel
Rihanna is the armpit of those photos.ReplyCancel
SJP wins!ReplyCancel
Whoa, rhianna looks good. Poor MaggieG and her butterface. Bless her heartReplyCancel
Uptown looks like a Frontier Land princess.ReplyCancel
This is a nice mix of gorgeous and hideous.
Victoria and SJP – amazing!
Maggie – I wouldn't use this fabric to make drapes with.
Elizabeth Olsen looks a bit out of place. I don't like the purse with that dress. Looks like she bought shoes at McDonalds.ReplyCancel
First Reactions:
Kate Upton: What the…?!!!
Gabrielle Union: Huh? Wait. WHAT?!!
SJP: Wow. Check out Andy Cohen's date!!ReplyCancel
Upton looks like a reject form Le Miz. RiRi looks great. Posh looks good, but boring. SJP is rockin' the look, even if I don't like it.
No comment whatsoever on poor Mags. Jesus.ReplyCancel
Somebody tell Olson that the ice rink is closed for the season.
Love Maggie's hair. (This is my version of "if you can't say something nice…") (I do love it though…)
Can't figure out what the hell Upton is even wearing. There's no cohesion between the outfit and the jewelry and the makeup. I didn't think Lima, Kloss, or the other one looked outstanding either, but at least it's not this Dr. Quinn Medicine Woman goes to the barn social getup that seems to be happening here…ReplyCancel
I'm going to try saying nice things this time…
Chloe M.'s hair looks really pretty.
Victoria Beckham keeps showing again and again that it's totally fucking bullshit that the Kardashian Kash Kow got the cover of U.S. Vogue before she did. Anna Wintour is stupid.
Elizabeth O.'s shoes are cute.
Lake Bell looks… very Lake Bell like.
Rihanna managed to to cover up all of her lady bits!
Blake Lively's back looks really good in that picture of Maggie G.
Skipping Gabrielle…
Kate Upton's… necklace looks nice?
SJP *killed* in this gown. Ahhh-mazing!ReplyCancel
Agree with everyone else – SJP is rocking that dress. I can't help but really love her.
Upton dress is horrid and from the look on her face she knows it.ReplyCancel
Now, see…I kinda like Chloe's dress. It is age appropriately modest and actually interesting. I also like Maggie G as a blond.ReplyCancel
Yep Victoria is definitely the best in that lot if not one of the best of the night – Keep it Simple Stupid works for fashion as well as most things in life.ReplyCancel
Clearly a lot of stylists were not earning their money last night – were the designers not being generous or co-operative?ReplyCancel
SUP looks beautiful. HOWEVER… what you're not seeing is the HUGE "Oscar de la Renta" splashed across the bottom back of the dress IN RED. It's incredibly gauche.ReplyCancel
Gabrielle=hoochie mamaReplyCancel
Riri's dress reminds me of this
Chloe: age appropriate…cute
Victoria: NICE
Eliabeth: first pic that makes me stabby
Lake: ((YAWN))
Rhi: Uh huh..((nods head in the affirmative))
Maggie: I actually like this dress. Is it for the MET….NAH
Gabby: Chile PLEASE..NO
Kate ((laughing hysterically))
SJP: I want the colors to be reversed so badly. I dunno…ReplyCancel
Ri RiReplyCancel
"Upton looks like a saloon gal from Gunsmoke." THIS!
Still not liking the SJP dress. RiRi did okay and VB looks good but boring.
HATE Chloe's dress. Too much trying to happen there. At least it's age appropriate I should say.
Nothing Olsen is wearing matches or brings this together. Shoes look comfy though.
Contrary to what others have said here I just don't like blonde on Maggie.ReplyCancel
Kate Upton broke the first rule of journalism: "Never bury the lead". If you're Kate Upton and you hide your ample bust there's really no reason for you to be a celebrity anymore.ReplyCancel
Lake bell looks AMAZING. SJP and Maggie's dresses are interesting. Never in the history of anything have I seen a hotter mess than Elizabeth Olsen at this Gala. She looks like an ice-dancer with McDonalds colored shoes. Her bag doesn't match at all and her stylist (she probably doesn't have one) needs to be fired. Such grossness! Well, at least she isn't wearing the glorified Birkenstocks her sisters are so fond of.ReplyCancel
Kate Upton looks horrifying. Her people played a joke on her!ReplyCancel
That was my first thought too – she's being Carrie! I love her style and attitude here.ReplyCancel
SJP for the win! She looks like a stah! This is a fantastic representation of the theme. Not really loving the signature on the back but I can see how you could look at that dress and say "it's a work of art, Oscar dela Renta, can you please sign that masterpiece for me". I think she looks like she just stepped out of the black and white Ascot scene in My Fair Lady.
I love Posh's dress (it's her own design)but don't feel it's a great fit for the theme of this event.
Lake Bell looks great but Elizabeth Olson is a big fat fail from head to toe! If a stylist did this to her, she needs to fire that person.ReplyCancel
Yo, Jason Blue!ReplyCancel
Well, I refuse to be nice after this visual assault. These women were too desperate to be seen there. If a designer offered a crap design, they should have walked out the door, they paid $50k to be at this awful event.
Chloe trying too hard to shed the "dating her brother" rumors.
Victoria is Fine. At least she more than belongs there, unlike the majority of contestants.
Elisabeth Olsen, who?? Is she an off strip Vegas hooker that someone brought on the cheap and she snuck out of the room?
Rihanna looks like a dirty skank. No fault of the designer in this case. I just can't with this idiot.
Who the Hell is Lake Bell? She looks nice in that dress.
Maggie & Gabrielle, both of you, just stop it.
SJP for the win! The red signiture was classy for this event. It would have been gauche for any other red carpet.ReplyCancel
Oh, and how could I ever forget Kate Upton? Easy.ReplyCancel
Kate Upton reminds me of an old time saloon working girl.ReplyCancel
How can the Trollsons look younger than their younger sister? Elizabeth Olson looks like she just escaped from her high skating competition and put on the wrong shoes. Everything is wrong on that Olson. The make-up sucks, the shoes are beyond fug, the lack of a pedicure. The list is just endless. At least her older sisters pulled themselves out from under their bridge to clean up.ReplyCancel
Where to start?
SJP's gown from behind looks like she had an "accident". You ladies know what I'm talking about.
Kate Upton.
Gabrielle Union thought she was going to the annual West Indian Day Parade on Eastern Parkway in Brooklyn and wore her best Carnival outfit.
Maggie Gyllenhaal.
I don't like Rihanna's Stella McCartney. It fits. It's well tailored. Even the shoulder pads work. I just don't like it.
Posh's makeup is horrible and takes away from the gown. I think she wore white better than Rihanna though.
Elizabeth Olsen.
You know how your mother told you if you can't say something good don't say anything? I'm working on that. I partially succeeded.ReplyCancel
If you've ever been to Carnival in Trinidad you know what I mean about Gabrielle Union's "dress".
Saloon working girl chic is the best way to describe Upton's attire.
This is why SJP's gown isn't a winner.
Gabi, you should have worked harder to find a matching top, a heart shaped bodice in black sequin that matched the skirt would have made hootchie, stunning.
Ms Upton, you should never have did whatever you did to that " designer ". Hopefully, your abject humiliation was payback enough. Gotta admit, this guy was good. From the black foreskin eating her legs to the matching " crown" mobcap, this guy gives Good Revenge.
SJP looks amazing per usual. Wtf is Kate uptown wearing? She looks like an old timey funeral director.ReplyCancel


text: The exclusive embossed, steel seat pan features a 3" integrally molded polyurethane foam and serpentine springs to ensure a comfortable, shift-resistant seat cushion. Two independent, fully operational hinge mechanisms guarantee consistent 3/4 safety fold without adjustment for the life of the chair. Upholstered back inner consists of polyurethane foam over a compound curved, steel inner panel, shaped for comfort and full back support. One-piece cast iron standards for either floor or riser mount.

subset: commoncrawl


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Seychelles In Good Hands Wedge Sandal
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Item # 270094
Put your best foot forward in these sandals from Seychelles. The In Good Hands will never disappoint with its woven detailing.
- Woven leather upper
- Ankle strap with adjustable buckle
- 1" platform, 4½" suede covered wedge
- Synthetic sole
- Imported
- View more Women's Seychelles Shoes
By: smkay13
Location: California
May 11, 2013
Love them
"I love these shoes. They are slightly long (I may have to have the elastic in the buckle shortened after it stretches. I fear it might become too large). I've found that my foot has "grown" to an 8 over the last couple of years, so sometimes an 8 is still not quite the right size, but a 7.5 is too small. These are my new favorite shoes. I can wear them all day walking and not have any pain! Yay. I would definitely recommend them. I'm now looking for my next pair of Seychelles."
By: KaylaS12
Location: Seattle,wa
April 25, 2013
Like Cinderella's Slipper
"...these fit me perfect like they were made for me. I am very excited about these shoes. The quality on them is really good, the red leather looks great. i bought these for a wedding so I know I am going to be on my feet all day and dancing the night away and I think these will be perfect.I ordered a size 7.5 - my "normal" size and a 7 since I haven't bought a pair of seychelles in a while and the 7 is what fit me liek a glove in every way."
By: CGRN
Location: North NJ
March 22, 2013
Love love love these wedges!
"Not too high,,,.super comfy...perfect for day and night!Love the thicker straps around toes,,,easier to walk in and makes it more comfortable....still sexy to show enough toes :)"
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text:
Vogue Prairie Angel Flat
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Item # 276559
Take your look from drab to fab in this colorful Vogue flat. The fabulous Prairie is the perfect way to spice things up.
- Woven fabric upper
- Cushioned insole
- Synthetic sole
- Imported
By: daphy
Location: ny
August 27, 2013
"Like it.. It runs a little narrow.. But love the color and the style"
By: Mel26
Location: NY, NY
April 23, 2013
Beautiful color.... nice shoe
"This shoe looks great on........ Blue color is beautiful and the design is very flattering. I wear a size 6.5 and this is true to size..... I got it yesterday and was very excited to see that it is exactly as I expected. I will be buying the yellow one too."
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text:
Feb 212011
Sometimes I like to look at what offers the open source world on the games side, today I want to introduce three little-known games that run on our beloved penguin.
For this article I have selected five games that I had never heard of, but from the first glance i've took to them they seem very promising; and I apologies with the developer of them, some are probably already well known and widespread in the community.
If the topic interests you I suggest also to check my previous articles regarding games:


text:
Connect with 20/20:
One of the first things taught to novice opticians is how to take a binocular PD with a millimeter ruler. But we're in an era that's about to be ruled by digital centration devices and tablet apps, so how much useful information can be realized from such an elementary method? In a word, plenty. Let's take a look at how position of wear fitting values are obtained through measuring by hand:
The ECP aligns himself approximately arms-length away from the patient, while lining up his sighting eye directly over the subject's eye. Ask the wearer to fixate on the sighting eye of the ECP.
The ECP uses the actual frame, complete with lens templates and fully fitted, and a marking pen to dot the pupil center or corneal reflex for each eye. Care must be taken to have the wearer assume as natural a posture as possible. It is recommended that the ECP observe the patient's posture before and after the measurement, as well as while standing and seated. Individual discretion in modifying this measurement is encouraged if the ECP observes notable postural deviations.
Using a method similar to the one above for pupil height, first the ECP marks the pupil with the wearer's posture as relaxed and natural as possible. Then, while looking from the side, help the wearer modify their head angle until the plane of the frame front is perpendicular to the floor. Mark the pupil for this position as well. Now, using Martin's Rule of Tilt in reverse, measure the distance between these two marks. Multiply by two and you have determined the effective pantoscopic tilt. Various plumb-style devices are also available to measure pantoscopic tilt.
As in measuring for pantoscopic tilt, keep the wearer's frame front held perpendicular to the floor, and use either a distometer or a ruler to measure from the corneal apex to a point directly opposite on the back of the template or lens' surface. This method is the proper way to obtain vertex distance by hand.
When done manually, determining a frame's panoramic angle is the only position of wear measurement that is not performed with the frame on the wearer's head. Using either a protractor or a similar tool, such as a panoramic gauge, the panoramic angle is essentially "eyeballed" by sighting a line, or chord, across the nasal and temporal outer limits of the eye wire. Visually extending this line to the reference scale allows determination of the wrap angle.
Another useful tool for measuring panoramic angle is the Panorameter by Shamir, which actually measures effective wrap at the PD. To distinguish its values from the more traditional ones gleaned with a protractor, its measure value range is adusted to lie between 90 and 120 degrees. It is important to not simply subtract 90 degrees from its found values and try to input Panorameter measurements into a conventional lab order. The augmented value range tells the lab you employed a Panorameter.
—Barry Santini
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© Copyright 2017 Jobson Medical Information LLC. All rights reserved. Reproduction in whole or in part without permission is prohibited.


text:
Qupid Arrival-19 Wedge Sandal
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Item # 284332
Let the Qupid Arrival announce your arrival. This fabulous wedge is the perfect statement sandal. The rhinestone covered platform and heel add a dose of pizazz and sparkle to your footwear style!
- Suede upper
- Ankle strap buckle detail
- Back zipper for easy on/off
- Rhinestone embellishment
- 1¾" platform, 6" rhinestone covered wedge
- Synthetic Sole
- Imported
- View more Women's Qupid Shoes
By: Mstutt
Location: Atlanta
February 06, 2014
"This is a very cute shoe and I know I'm going to get tons of compliments on it! But be careful! The wedge is high and they're not all that comfortable. But beauty is pain at times. Just don't go on a shopping trip in them."
By: MargoRite
Location: Stone Mountain, GA
August 30, 2013
Stepping High
"I love this shoe, it's very comfortable but the wedge is high. You won't be walking long in these. But the style and comfort are awesome!"
By: Amadeus
Location: Brick, NJ
June 14, 2013
Not for the feint of heart
"The wedge is very tall and very thin (feels more like a stiletto than a wedge), and the angle is very steep. Don't plan on going for any long walks in these. They run pretty true-to-size. The colors of little gems look great in person. You're sure to get comments on these shoes!"
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Secretary of State Hillary Rodham Clinton is making one last diplomatic effort in the Middle East as she gets ready to retire from government service -- at least for now.
WASHINGTON — The history books may speak highly of Secretary of State Hillary Rodham Clinton, but Middle East peace won't be one of the reasons.
Time and again over her four years in office, tentative steps toward reconciliation between Israelis and Palestinians have been dashed, just as they have been for most of her predecessors.
In that context, Clinton's shuttle diplomacy between Jerusalem, Ramallah and Cairo tonight and Wednesday amounts to a last-minute effort to prevent further deterioration in a situation that, at best, has remained mostly stagnant throughout the Obama administration.
State Department spokeswoman Victoria Nuland said Tuesday that the goal is to restore calm and improve conditions in order to "get Israel and the Palestinians back to the table to discuss lasting solutions."
Clinton is likely to leave office early next year after two decades on the national stage as first lady, U.S. senator and America's top diplomat. Her favorable ratings in national polls are sky-high at 66%, and her prospects as the next Democratic presidential candidate are higher than anyone else's — should she seek the nomination.
Yet her many successes as secretary of State — from the diplomatic opening to Burma, which she visited with Obama this week, to the coalition-building that led to the overthrow of Libyan strongman Moammar Gadhafi — may be overshadowed by what she and Obama could not do: bring peace to the Middle East.
Asked about that in an interview with USA TODAY in May, she joked about the degree of difficulty. "I can't remember who got that done," she said. "I can't remember that exactly."
Besides the obvious difficulty of bringing israel and the Palestinian Authority together — further complicated by the administration's refusal to meet with Hamas, which governs Gaza — Clinton cannot stop the world long enough to ignore other hot spots such as Iran and North Korea.
The administration has made Asia its top diplomatic priority, as evidenced by the trip Obama and Clinton just completed to Burma, Cambodia and Thailand.
"It would be, I think, malpractice to say, 'I'm only working on this thing, and I'm just going to beat it into the ground. Everything else can just wait,'" she said in May.
The administration tried to make inroads in the Middle East initially. Obama's first phone call to a foreign leader as president was to Palestinian Authority President Mahmoud Abbas. The administration came down hard against Israeli settlements in the West Bank but later backed off. In June 2009, Obama delivered his much-ballyhooed speech to the Arab world in Cairo. Former Senate majority leader George Mitchell, who brokered peace in Northern Ireland during the Clinton administration, was installed as special envoy to the region.
Yet as the years have passed, "they've tried to make it look like they're doing something but without really doing anything," says Diana Buttu, a Palestinian-Canadian lawyer and former spokesperson for the Palestine Liberation Organization.
Now the administration can't afford to remain on the sidelines, says Aaron David Miller of the Woodrow Wilson International Center for Scholars, a former adviser to six secretaries of State. Clinton, he says, could wind up shuttling between the various sides, including new Egyptian President Mohammed Morsi, who has said he wants to broker a cease-fire.
"They can no longer afford to be not much more directly identified with this issue," Miller says of the Obama administration, describing the Middle East as a "cruel and unforgiving world."
Some see U.S. diplomacy paying immediate dividends. Heather Hurlburt, executive director of the liberal National Security Network, says just the pending arrival of Clinton and United Nations Secretary-General Ban Ki Moon may have prompted Egypt and Hamas to consider a cease-fire.
Still, no one should expect a kumbaya moment to come from Clinton's visit, she says.
"This is not something she can accomplish and get home and have a turkey," Hurlburt says. "It's going to be handed to whoever her successor is and others in the administration."
Contributing: Oren Dorell


text:
Unisex. Large main compartment with U-shaped zippered opening. Water resistant rubberized bottom. Large front zippered pocket. Ventilated endcaps for wet items. Air mesh comfortable grip handle. Detachable and adjustable shoulder strap. Embroidered Logo. Side wet pocket with organizer. Cell phone and goggle pouch. 100% Polyester Dobby, PVC Free Textiles. Size: 25in L x 11in W x 12in H
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text:
Spring Step Lotus Sandal
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Item # 268395
Show off your carefree summer style in the Spring Step Lotus! With whimsical florals and earthy design details, this cute sandal will stand out in a crowd.
- Leather upper
- Hand painted
- Cushioned insole
- ¾" platform,2½" covered wedge heel
- Synthetic sole
- Imported
By: happybird
Location: Arizona
November 07, 2013
Beautiful -Wished they'd last
"I bought these shoes for their looks and comfort. After three weeks the leather strap between the toes on one of the shoes snapped off. Very disappointed."
By: Laura99999
Location: Palmer, CO
September 11, 2013
Love these sandals!
"These sandals are soooo cute and very unique. They are perfect fit and look much better in "person". I love the bright colors, they add a lot of style to any outfit! Very classy look and excellent quality!"
By: Candace0428
Location: Charlotte, NC
August 27, 2013
Runs alittle short...
"I love this color and look of shoe! Order half size larger for a comfortable fit!"
By: SuzyQH
Location: Chicago, IL
July 05, 2013
"I bought these because they are like nothing I have. Received immediate compliments on them the first time I wore them!"
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text:
Bond, a 2012 graduate of Rockcastle County High School, has demonstrated a longstanding interest in art, according to his mother, Lisa. "Cory began drawing with sidewalk chalk at the age of three. Art is everything to him," she said. "It is as important to him as breathing. He communicates and expresses himself through art."
Bond, whose works have been displayed at the Rockcastle County Public Library and Rockcastle Regional Hospital, hopes that there is sufficient interest in his artwork to result in a career. Private collectors have begun to show an interest in his work, which may be viewed on his website at corybondartwork.com.
Bond enrolled in SCC's Drawing I course, but found a love for painting while enrolled in the Painting I class. He continues to study art at SCC. "Cory's interaction with his peers in the studio has been positive," stated Darlene Libbey, associate professor of art at SCC. "We are teaching each other, and the day I stop learning from my students is the day I need to retire."
"Cory's World" will be on display in the SCC East End Gallery from April 1 – 30. A catered reception will be held in the gallery on April 3 from 5:00 – 6:30 p.m. The gallery is located in Stoner Hall on the Somerset Campus, 808 Monticello St., Somerset, KY. For questions about the exhibit, contact email@example.com.


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Crista Flanagan >> See More Celebrity
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A salute to the coolest show on television, starring Crista Flanagan as Sterling Cooper's naive office girl Lois Sadler. That Mad Men's Crista Flanagan is hilarious isn't news, but thanks to photographer Robert Maxwell the world can now get a glimpse of the ad agencyâ€...
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text:
Tobacco Control Act: Resources and FDA Regulations
- Overview
- Buttons
No More "Light," "Low," or "Mild" Cigarettes
Tobacco Regulation
July 22, 2010, marks another milestone in tobacco control and prevention. As of that date, the law prohibits the tobacco industry from distributing or introducing into the U.S. market any tobacco products for which the labeling or advertising contains the descriptors "light," "low," "mild," or any similar descriptor, irrespective of the date of manufacture. However, consumers may continue to see some products with these descriptors for sale in stores after July 22, because retailers are permitted to sell off their inventory.
A Brief History
Cigarettes labeled "light," "low," or "mild" are often called "low-yield" because they deliver less than 15 mg of tar when measured on a standardized smoking machine. After a 1964 historic Surgeon General's report on smoking and health, cigarette manufacturers made changes in cigarette design to achieve and promote low-yield cigarettes (e.g., filters, ventilation holes, chemical additives). Advertisements implied that the low-yield cigarettes were safer than regular cigarettes. However, there is no convincing scientific evidence to indicate that low-yield cigarettes are safe. No cigarette design changes have resulted in a decrease in the diseases caused by smoking.
Protecting Public Health
Prohibiting the use of terms like "light," "low," and "mild" is an important step to help protect the public health. Many smokers mistakenly believe that cigarettes marketed with these descriptors cause fewer health problems than other cigarettes. Studies have found that smokers who use light cigarettes do not reduce their risk for developing smoking-related cancers and other diseases, that switching to light cigarettes does not help smokers quit, and that switching to light cigarettes may actually decrease the motivation to quit. All cigarettes are harmful to health—regardless of their taste, smell, label, or packaging color. There is no such thing as a safe cigarette.
Help to Quit
Millions of former smokers have successfully quit. In fact, today there are more former smokers than smokers. For help, visit www.smokefree.gov or call 1-800-QUIT-NOW (1-800-784-8669).
For More Information
Centers for Disease Control and Prevention
- New Tobacco Controls Have Public Health Impact
- Low-Yield Cigarettes
- Smoking Cessation
National Cancer Institute
- The Truth About Light Cigarettes: Questions and Answers
- Risks Associated with Smoking Cigarettes with Low Machine-Measured Yields of Tar and Nicotine [PDF–2.90 MB]
U.S. Food and Drug Administration
- Page last reviewed: August 16, 2016
- Page last updated: August 16, 2016
- Content source:


text:
Brass Boot Keysen Loafer
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Item # 254050
Brass Boot offers fabulous footwear with ultimate comfort and style, and the Keysen penny loafer is a perfect example! This handmade, classic slip-on will live up to your standards with its fine leather and padded insole, and is a great dress shoe for the office.
- Smooth and pebbled leather upper
- Decorative penny keeper strap
- Round moc toe
- Genuine sheepskin lining
- Cushioned leather insole
- Leather sole with synthetic heel for increased traction and durability
- Imported
- View more Men's Brass Boot Shoes
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Everyone has an opinion. Here's your chance to share yours! Be the first to write a review of this product and help your fellow shoppers pick the best of the best.


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SEGA is a video game developer headquartered in Tokyo, Japan. The SEGA Online Operations team builds and maintains Internet platforms for the company's western divisions and subsidiary studios. These subsets include the main public websites such as sega.com; popular game forums such as Football Manager and Total War; and online game servers. The team's role is to drive development in cloud-based platforms for current and future online requirements.
Stuart Wright, IT & Network Director for the Online Operations team, explains why they opted to work with Amazon Web Services (AWS): "We chose AWS because it is a market leader offering low barriers to entry and a rapidly evolving feature set. The AWS Cloud allows us to have flexibility in our deployments and scaling that traditional server hosting does not provide." He adds, "The field is now sufficiently mature for us to consider AWS part of our long term digital strategy."
The team is migrating all public websites away from co-located servers onto cloud-based systems. Wright says, "Our web servers are scaled Amazon Elastic Compute Cloud (Amazon EC2) clusters, and web content is accessed from pairs of high-availability Amazon EC2 networked file servers. Images and other static files are published to Amazon Simple Storage Service (Amazon S3) buckets and video content is served via Amazon CloudFront to a global audience."
In addition, the team uses Amazon Relational Database Service (Amazon RDS) databases to store forum threads, site content, and project configuration data. They use the high availability Multi-AZ database deployment to handle live game metadata and user-generated content. This adds enterprise-grade fault tolerance for protecting their customer data. By managing time-consuming database administration tasks, Amazon RDS allows SEGA to focus on business critical applications.
Figure 1 provides an overview of the team's webserver architecture:
As the team's build process is being continually refined, they are moving from simple build scripts toward AWS CloudFormation templates. Wright describes the current configuration: "Our web servers self build on startup from a base AMI using Puppet and Amazon EC2 metadata to determine the project and build modules. Content publishing and synchronization are done using PHP and tools such as s3sync."
Migrating to AWS has offered the team several advantages. Rapid on-demand server availability has been a great help when unplanned load spikes hit after game launches. Wright reports that another benefit of migration has been the reduction of server costs by over 50%.
Wright also reports that the migration process was generally smooth; however, the team found migration of similar services across regions to be more complicated than they expected due to region-specific AMI IDs, security groups, etc.
The team intends to make more use of Amazon Simple Email Service (Amazon SES), Amazon Simple Queue Service (Amazon SQS), and Amazon CloudWatch as they integrate AWS services into their build and monitoring systems. In addition, they are looking into video streaming via Amazon EC2 and Amazon CloudFront for PR and product development uses, and high performance Amazon EC2 clusters may be useful in future game server deployments.
To learn more about how AWS can help support your Website needs, visit: http://aws.amazon.com/websites/.


text:
Did I Ever Tell You How Lucky You Are?
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- Brief Synopsis:
- Compared to the problems of some of the creatures the old man describes, the boy is really quite lucky.
- Long Synopsis:
- The skunk has troubles; no one likes its smell! The snake has troubles; peoples' fears won't quell. The porcupine has troubles; none will scratch his tail. The dog, I think, has troubles; fleas bite him without fail! To be a boy, then, I should say, Is best of all 'cause boys can play!
- Book Quality:
- Excellent
- Book Size:
- 49 Pages
- 9780394927190
- Publisher:
- Random House
- Date of Addition:
- 10/29/12
- Copyright Date:
- 1973
- Copyrighted By:
- Theodor S. Geisel and Audrey S. Geisel
- Adult content:
- No
- Language:
- English
- Categories:
- Nonfiction, Humor, Children's Books, Literature and Fiction, Poetry
- Grade Levels:
- Kindergarten, First grade, Second grade, Third grade, Fourth grade
- Submitted By:
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- Proofread By:
- Doug Maples
- Usage Restrictions:
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Section 30
1–4, David Whitmer is chastened for failure to serve diligently; 5–8, Peter Whitmer Jr. is to accompany Oliver Cowdery on a mission to the Lamanites; 9–11, John Whitmer is called to preach the gospel.
1 Behold, I say unto you, David, that you have
2 But your mind has been on the things of the
3 Wherefore, you are left to inquire for yourself at my hand, and
4 And your home shall be at your
5 Behold, I say unto you, Peter, that you shall take your
6 And be you afflicted in all his
7 And none have I appointed to be his counselor
8 Wherefore, give heed unto these things and be diligent in keeping my commandments, and you shall be blessed unto eternal life. Amen.
9 Behold, I say unto you, my servant John, that thou shalt commence from this time forth to
10 And your labor shall be at your brother Philip Burroughs', and in that region round about, yea, wherever you can be heard, until I command you to go from hence.
11 And your whole labor shall be in Zion, with all your soul, from henceforth; yea, you shall ever open your mouth in my cause, not


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- National Active and Retired Federal Employees Association Santa Cruz Chapter 54
This local chapter of a national organization is open to those retired from Federal Civil Service. Its purpose is to keep membership informed on items related to retired employees and to assist member... [Full Record]
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A social club for retired men. Sons In Retirement was founded in 1958 and has 175 branches. ELIGIBILITY: Retired man sponsored by member. FEES: No fixed dues but contributions are expected.... [Full Record] [Add to Personal List]
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Group of retired men who meet for lunch. This is one branch of a large organization with many branches and members, whose slogan is "Promoting the Independence and Dignity of Retirement." ... [Full Record] [Add to Personal List]
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More Evidence That Science is Still Clueless About Global Climate Controls
Levi Beckerson
January 8, 2010 7:34 PM
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For all we know, Al Bundy's socks may be the cure for the global climate crisis.
Will the war for global warming ever be won? That depends on the amount of information we can harvest, analyze and extrapolate from. In all likelihood, the only way we will know for certain if the Earth is heading for a global warming disaster is by waiting another few thousand years and looking at history books.
But, for those not comfortable with the wait and see approach, scientists continue to plunge into one of the crucial factors thought to govern global (I'm trying not to snicker) climate change, the global carbon sink system. Roughly composed of just about every living and even more dead things, these parts of local, regional and whole-Earth ecosystems are under high scrutiny as researchers try to understand how present day climate change will further affect future climate change. The popular idea seems to be that global warming is like a snowball rolling downhill – as it rolls it picks up more snow and eventually hits something and explodes. Exploding is bad for the Earth, honest.
From the University of Colorado at Boulder comes a study supporting the theory that extended growing seasons may not be the boon for the carbon sink that many have previously thought. At least not for subalpine conifers such as the lodgepole pine, subalpine fir and Englemann spruce. It turns out these trees depend much more upon snowmelt for their summer water fix than rainfall, and in years where spring comes early due to mild winters and low snowfall,
the trees actually take in less carbon dioxide
over the year than when spring arrives late with heavy snow still on the ground. Up to 60% of their internal water supply from stems and needles was identified to be from spring snowmelt rather than rainfall in the fall months. We can thank our friends the hydrogen and oxygen atoms for this precise identification work.
Since around 70% of the western USA's carbon sink is found in these subalpine forest ranges, watching the snow caps shrink yearly would definitely affect their ability to operate to capacity, should this study be accurate. Facts don't lie; snow good, carbon dioxide bad.
On a somewhat brighter note, according to researchers at the National Oceanographic Center, Southampton, another very large and poorly understood carbon sink may be completely underestimated in present carbon cycle models. Echinoderms, which comprise a vast portion of the ocean's calcium carbonate dump,
may sequester much more carbon yearly than previously thought
Echinoderms suck in carbon from seawater to form their skeletal systems and include such happy marine animals as star fish, sea urchins and sea cucumbers. When these animals find the end of their lifecycle, they typically sink to the ocean floor with their captured carbon and become indefinitely buried in the sediments. Some of the calcium carbonate finds its way back up the "biological carbon pump," but probably much less than is taken down to the depths.
This could mean that the ocean is once again showing itself to be far more excellent at helping regulate global carbon levels, or it could just mean scientists still don't really understand what's going on in there.
If these studies only prove one thing it is that we, as a global community, race, organism and observer still have very little understanding in the way all of our ecosystems work together to regulate the Earth's climate. It's far too early for any sane person to jump on the "we're melting, melting" or "Minnesota never left the ice age, what's your problem" camps. There simply aren't enough data to concretely support any given theory with certainty and these kinds of discoveries are shining examples of why.
"It seems as though my state-funded math degree has failed me. Let the lashings commence." -- DailyTech Editor-in-Chief Kristopher Kubicki
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Deluxe Room │ 1 King │ Non-Smoking
The Deluxe King Room ranges from 250 - 350 square feet and includes one king bed with a pillow-top mattress. Electronic features include USB charging stations and a 47-inch LED flat-screen TV. The room is designed with light, modern furnishings and pops of color. Room service is available.


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Isla Mujeres Vacation Rentals
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With the advent of prostate-specific antigen (PSA) screening and the increase in the number of transrectal ultrasound–guided biopsy cores, there has been a dramatic rise in the incidence of low-risk prostate cancer (LRPC). Because >97% of men with LRPC are likely to die of something other than prostate cancer, it is critical that patients give thought to whether early curative treatment is the only option at diagnosis.
To identify a group of men with LRPC who may not require initial treatment and monitor them on our active surveillance (AS) protocol, to determine the percentage treated and the outcome and to analyze the quality-of-life data.
Design, setting, and participants
We defined patients eligible for AS as Gleason ≤6, PSA ≤10, and two or fewer biopsy cores with ≤20% tumor in each core.
Kaplan Meier analysis was used to predict the 5-year treatment free survival. Logistic regression determined the predictors of treatment. Data on sexual function, continence, and outcome were obtained and analyzed.
Results and limitations
The AS cohort consisted of 230 patients with a mean age of 63.4 yr; 86% remained on AS for a mean follow-up of 44 mo. Thirty-two of the 230 patients (14%) were treated for a mean follow-up of 33 mo. Twelve had a total prostatectomy (TP). The pathologic stage of these patients was similar to initially treated TP patients with LRPC. Fourteen underwent radiation therapy, and six underwent androgen-deprivation therapy. Fifty percent of patients had no tumor on the first rebiopsy, and only 5% of these patients were subsequently treated. PSA doubling time and clinical stage were not predictors of treatment. No patient progressed after treatment. Among the AS patients, 30% had incontinence, yet <15% were bothered by it. As measured by the Sexual Health Inventory for Men, 49% of patients had, at a minimum, moderate (≤16) erectile dysfunction.
If guidelines for AS are narrowly defined to include only patients with Gleason 6, tumor volume ≤20% in one or two biopsy cores, and PSA levels ≤10, few patients are likely to require treatment. Progression-free survival of those treated is likely to be equivalent to patients with similar clinical findings treated at diagnosis.
Keywords: Prostate cancer, Active surveillance, Sexual function.
1. Introduction
With the advent of prostate-specific antigen (PSA) screening and the increase in the number of transrectal ultrasound (TRUS)–guided biopsy cores, there has been a dramatic rise in the incidence of low-risk prostate cancer (LRPC; Gleason 6, T1c, low volume) [1] and [2]. Based on patients identified between1996 and 2003, 91% of new cases of prostate cancer (PCa) were expected to be diagnosed with clinically localized disease and an anticipated 5-yr relative survival approaching 100% [3]. As many as 50% of PCa cases detected by screening may be "over-diagnosed," with 5–12 yr of lead time before treatment becomes necessary [4]. Interestingly, treatment patterns have not reflected the downward stage and risk migration of these newly diagnosed LRPC patients [5] and [6]. Consequently, the dilemma regarding treatment decisions has become more challenging. Because >97% of men with LRPC are likely to die of something other than PCa [7], it is critical that patients give thought to whether early curative treatment—with a 50% likelihood of negative health-related quality of life (HRQoL) sequelae—is the only option at diagnosis.
The concept of active surveillance (AS) for LRPC has evolved since the 1990s. Initially, watchful waiting (WW) was advanced as a viable strategy for LRPC patients, delaying treatment and its associated comorbidities until clinical progression was observed [8] and [9]. Patients electing WW had localized disease but were older or had comorbidities that precluded them from having curative treatment. Often, those treated were prescribed palliative therapy, such as androgen-deprivation therapy. D'Amico et al created preliminary guidelines in 1998 to define LRPC and thus those patients eligible for AS: PSA levels ≤10, Gleason score <7 (no 4 or 5 in biopsy), and stage T1a–2a disease [10]. Over the past 10 yr, PSA velocity and density and cancer volume per core have contributed to refining the literature on AS [7] and [8].
The goal of this study was to investigate how best to follow LRPC patients who have made the decision to be carefully monitored on AS and to determine what percentage of AS patients were treated. In addition, if patients met the criteria for treatment while on AS, were they likely to be cured with treatment? We also analyzed the data on quality of life (QoL).
2. Methods
Since February 1992, men with LRPC have been identified and offered a surveillance regimen. Guidelines were initiated to define eligibility for AS: Gleason score ≤6, PSA levels ≤10, and two or fewer biopsy cores with ≤20% tumor present in each core. All patients had T1a–T2 disease. Frequently, patients came to our center with a diagnosis of PCa: Their diagnostic biopsy usually consisted of a minimum of 10 cores. Curative treatment (total prostatectomy [TP] or radiation therapy [RT]) was urged on increase in tumor volume, Gleason grade >3, or more than two positive cores on rebiopsy. (We find the term total prostatectomy to be more appropriate than radical prostatectomy[11].)
Patient data were recorded in a retrospective database, approved by the institutional review board and designed to analyze clinical and pathologic information. The data were abstracted from the patient chart following patient visit and entered into the database.
All patients had to satisfy the requirements of the AS guidelines. Patients who had <12-mo follow-up and/or were ≥80 yr of age were excluded from the cohort. Patients 75–79 yr of age who at the time of diagnosis were healthy enough for curative treatment were offered AS.
Beginning in January 2007, data were obtained at each visit using the Sexual Health Inventory for Men (SHIM) [12] and the International Conference on Incontinence Short Form (ICI-SF) [13]. These questionnaires replaced the verbal data initially collected as part of the history and the physical.
Each AS patient was followed every 3–4 mo with a PSA and rectal exam (RE) for the first 2 yr, then every 6 mo. In addition, after 2000, a laterally directed and peripherally targeted TRUS biopsy of 10–12 cores was performed 9–12 mo after the initial visit (the first rebiopsy), and then every year or earlier if there was a dramatic rise in PSA or a change on RE. Patients were asked to sign a document that emphasized the guidelines for AS and the need for vigorous monitoring. The decision to discontinue AS was based on (1) Gleason grade >3 on rebiopsy, (2) increase in tumor volume measured by percentage of tumor in each core, (3) increase in the number of positive cores, or (4) personal preference.
We identified patients from our TP database who met the criteria for AS but who elected TP at diagnosis. We compared their outcome with patients who underwent TP after being followed on AS. Statistical analysis was completed using SPSS v.17 (SPSS, Chicago, IL, USA). Descriptive data spanning time from diagnosis through follow-up were analyzed. Kaplan-Meier analysis was used to characterize the 5-yr probability of treatment-free survival as well as the 5-yr probability of treatment-free survival as determined by rebiopsy findings. Logistic regression analysis was performed to determine the best predictors for no treatment. A p value ≤0.05 was considered statistically significant.
3. Results
Two hundred thirty out of 250 patients met the criteria for AS (20 patients had not been followed for 12 mo). The mean age of the AS patients at diagnosis was 63.4 yr of age (median: 64; range: 42–79), with a mean PSA value of 5.07 ng/ml (median: 4.76). The mean follow-up for the cohort was 44 mo (median: 32; range: 12–208; Table 1).
Demographics of the active surveillance (AS) cohort versus treated AS patients
|AS cohort
|Treated AS patients
|No. of patients
|Age at diagnosis, yr
|Mean: 63.4
|Mean: 65.3
|Median: 64
|Median: 68
|Range: 42–79
|PSA at diagnosis, ng/ml
|Mean: 5.07
|Mean: 5.66
|Median: 4.80
|Median: 5.14
|Length of follow-up, mo
|Mean: 44
|Mean: 33
|Median: 35
|Median: 31
|Range: 12–208
|Range: 12–92
|Age at Tx, yr
|Mean: 68.5
|Median: 70
|Range: 44–84
|First SHIM score
|Mean: 14.2
|Mean: 16.9
|Median: 17.5
|Median: 21.5
|Last SHIM score
|Mean: 11.8
|Mean: 14.23 (before Tx)
|Median: 13
|Median: 20
AS = active surveillance; PSA = prostate-specific antigen; Tx = treatment; N/A = not available; SHIM = Sexual Health Inventory for Men.
Fifty percent of patients had no tumor on the first rebiopsy; 46% continued to have small-volume Gleason score 6 tumors. Six patients (2.5%) had Gleason grade 4, and three others had an increase in tumor volume. On the second rebiopsy, 15 patients had Gleason grade 4. On the third rebiopsy, three patients had Gleason grade 4. Five percent of patients who had no tumor in the first or second rebiopsy were treated, compared with 16.5% who had focal Gleason 6 on the first rebiopsy. There was no tumor in 49%, 52%, and 71% of the second, third, and fourth rebiopsies, respectively.
Of the 230 men in the AS cohort, 32 (14%) were treated over a mean follow-up of 33 mo (median: 31; range: 12–92). The mean age of the treated population at diagnosis was 65.3 yr of age; the mean PSA level (at diagnosis) was 5.66 ng/ml (Table 1). The mean age at time of treatment was 68.5 yr of age (range: 44–84).
Twelve of the 32 treated patients had TP, 14 had interstitial or external-beam RT (EBRT), and 6 underwent hormone therapy (HT; Fig. 1). Seven patients treated with TP had Gleason score 3 + 4 or 4 + 3 on the TP specimen; two had Gleason score 3 + 5 or 4 + 4 (Table 2). The mean follow-up post-surgery was 30 mo (median: 35). None of the TP patients have had biochemical recurrence (BCR). No patient has died of PCa.
Outcome of treated active surveillance patients with total prostatectomy (TP) versus initially treated TP patients.
AS = active surveillance; LHRH = luteinizing hormone-releasing hormone; EBRT = external-beam radiation therapy; TP = total prostatectomy; EPE = extraprostatic extension; SVI = seminal vesical invasion; BCR = biochemical recurrence; PCa = prostate cancer.
Results following total prostatectomy of treated active surveillance patients
|Gleason score at Tx
|Volume, %
|Follow-up, mo
|3 + 4
|3 + 4
|3 + 3
|3 + 3
|3 + 4
|3 + 3
|4 + 3
|3 + 4
|3 + 4
|4 + 4
|3 + 5
|3 + 4
Tx = treatment; EPE = extraprostatic extension; SVI = seminal vesical invasion; BCR = biochemical recurrence.
A Kaplan-Meier analysis predicted that 85.7% of the entire AS cohort would be free from treatment at 5 yr (Fig. 2). Logistic regression was performed to determine which variables best predict those patients who would likely not undergo treatment. PSA doubling time (PSA DT) and clinical stage were not predictors for treatment. Any tumor at the first rebiopsy was a predictor for treatment (p = 0.011; coefficient of 1.517).
Kaplan-Meier treatment-free survival curve.
The SHIM and ICI-SF were completed by 172 of 230 patients. On the ICI-SF, 30% of AS patients demonstrated some degree of incontinence; few were bothered by it (bother score >0). The mean initial and final ICI scores were not significantly different 1.16 and 1.1 respectively.
Forty-nine percent of patients had at least moderate erectile dysfunction (ED), as measured by the SHIM. The mean scores (initial mean score:14.2 [median: 17.50]; final mean score: 11.8 [median: 13]) also indicated moderate ED in the cohort at large. A paired-sample student t test analyzing the initial/last SHIM scores revealed that the last scores were significantly lower (p <0.001). The significant increase in ED was seen in three of four age groups (40–49; 50–59; 60–69; 70–79; Table 3). There was no significant difference in the mean age between patients with ED and patients with normal erectile function (p = 0.75).
Decline in erectile function in different age groups
|Age group, yr
|p value (first SHIM/last SHIM)
|Follow-up, mo
|Group I: 40–49
|p ≤ 0.019 (20/11.2)
|Mean: 36
|Median: 27
|Group II: 50–59
|p = 0.376 (18.1/17)
|Mean: 42
|Median: 30.5
|Group III: 60–69
|p ≤ 0.10 (13.5/10.7)
|Mean: 40.6
|Median: 31.50
|Group IV: 70–79
|p ≤ 0.032 (12.2/9.2)
|Mean: 47
|Median: 38.05
SHIM = Sexual Health Inventory for Men.
AS patients with SHIM scores ≥21 (30%) and normal erectile function at diagnosis were studied to determine whether multiple TRUS biopsies had an effect on potency. The group's mean age was 58.57 yr of age (median: 58.50). Interestingly, over a mean follow-up of 35 mo (median: 28), there was a significant increase (p ≤ 0.001) in ED (mean: 23.65 to mean: 17.98) from the initial SHIM.
Our AS guidelines were met by 219 out of 2100 patients who initially had TP rather than selecting AS. Only 22% of these patients contained Gleason grade 4 or 5 in the surgical specimen. In the 219 patients, 59 (27%) had a positive margin, 17 (7.5%) had extraprostatic extension (EPE), and 4 (2%) had seminal vesicle invasion (SVI; Fig. 1). There was no significant difference in the positive margin rate between initially treated patients and patients treated following AS (p = 0.52), EPE (p = 0.73), or SVI (p = 0.79).
4. Discussion
Today, clinicians recognize that a growing number of cancers detected by PSA screening are likely to be LRPC and may never be life-threatening during the patient's lifetime. Nevertheless, LRPC patients are often subjected to treatment and its HRQoL consequences without bettering their chances for progression-free survival (PFS) [14].
Although the percentage of patients who have treatment for LRPC after initial AS ranges from 17% to 33%, no markers accurately define which tumors "progress" [15]. There is concern among urologists that tumors, while being monitored, may progress beyond the opportunity for cure. Ploussard et al suggested that PCa patients initially diagnosed by a 21-core biopsy who then select AS had a higher likelihood of more favorable disease on TP [16]. Others have argued, though, that men diagnosed based on a more limited initial biopsy have also demonstrated favorable outcomes at treatment following AS [17].
Several critical factors should have influenced support of AS. Change in the technique of prostate biopsies and increased numbers of cores obtained have moderated grade migration on the surgical specimen. Over the past 15 yr, we found 20% fewer (from 47% to 27%) "under-graded" tumors than previously observed [18].
By carefully selecting the AS cohort to include only those patients who have been compliant with the guidelines of close surveillance and who have low-volume disease (≤20% of tumor in two or fewer cores), a relatively small percentage (14% in this cohort) have required treatment. Among those eventually treated with surgery or RT, no patient has progressed or died from PCa. Progression was defined as BCR. In the AS cohort treated with TP (12 of 32), tumor volume ≤20% was reported in 100% of the patients and a positive margin in 3 of 12 patients. All patients were free of SVI, and one patient had EPE (Fig. 1).
As in other reported studies [19] and [20], neither PSA DT nor PSA velocity was an indication for treatment in our cohort. Increase in Gleason score or tumor volume was the threshold to urge treatment. Even though our mean post-TP follow-up is only 27 mo (range: 2–47; median: 35), we are cautiously optimistic that the prognosis will likely be as good as those with initial TP. Change in clinical stage coupled with a rising PSA level triggered treatment in older patients (>80 yr of age after being followed) who elected HT. Only one patient elected treatment because of distress over living with untreated PCa.
Waning sexual function may be a common disease-specific concern for patients with PCa [21] and [22]. Beginning in 2007, all men with a diagnosis of PCa were asked to complete the SHIM. Of this subset of our AS cohort, 44% (first SHIM) and 56% (last SHIM) had at least moderate (≤16) ED. The significant increase in ED was seen in three of four age groups. The median follow-up was <3 yr; thus, age may not be the significant factor that affects ED in this AS cohort (Table 3).
Why are few men offered AS, and of those patients who are, why do so few choose it as an alternate strategy? There appears to be a lack of acceptance for AS [23]. In a study of 110 of our AS cohort, 67% reported that the physician who diagnosed their PCa did not offer AS as an alternative to treatment. This offer is critical because it was reported that as many as 57–70% of patients chose treatment based on physician recommendation [24].
Before PSA screening, nearly half of PCa patients were diagnosed with advanced disease (T3–T4) [10] and had a poor prognosis. The problem, therefore, is not in diagnosing PCa but in educating patients about risk-adapted alternatives. Patients have the right to know they have LRPC, and physicians should not feel compelled to treat every PCa patient. With comprehensive educational information and supportive care from the physician, as many as 45% of PCa patients could postpone treatment—maybe indefinitely [1].
Our study has some limitations. AS patients with no ED were evaluated to see whether repeated biopsies might alter erectile function, as suggested by Fujita et al [25]. Because we only started collecting data on QoL objectively in 2007, we are lacking sufficient data to draw conclusions because of the short time span and the small number of repeated biopsies between the first and last questionnaire. Another limitation of our study is the small number of patients treated with TP. A larger number of patients treated and longer follow-up are essential to better define the outcome of treatment following AS. Merging the data from multiple institutions might provide the most accurate outcome of treated AS patients.
5. Conclusions
Our data suggest that if the guidelines for AS are narrowly defined to include only those patients with Gleason score 6, PSA levels ≤10, and tumor volume ≤20% in two or fewer cores, a lower percentage of AS patients will likely require treatment when compared to other AS series. In our experience, the PFS appears to be equivalent to those who initiated treatment at diagnosis. With careful selection and close monitoring of LRPC, the dilemma regarding overtreatment and its impact on HRQoL, which may already be impaired at diagnosis, may be less of a dilemma—if and when AS is accepted as a viable alternative.
Author contributions: Mark S. Soloway had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: M. Soloway, Manoharan.
Acquisition of data: C. Soloway, Eldefrawy, Acosta.
Analysis and interpretation of data: C. Soloway, Eldefrawy.
Drafting of the manuscript: M. Soloway, C. Soloway, Eldefrawy.
Critical revision of the manuscript for important intellectual content: Kava.
Statistical analysis: C. Soloway, Eldefrawy.
Obtaining funding: None.
Administrative, technical, or material support: Acosta.
Supervision: Manoharan, M. Soloway.
Other (specify): None.
Financial disclosures: I certify that all conflicts of interest, including specific financial interests and relationships and affiliations relevant to the subject matter or materials discussed in the manuscript (eg, employment/affiliation, grants or funding, consultancies, honoraria, stock ownership or options, expert testimony, royalties, or patents filed, received, or pending), are the following: None.
Funding/Support and role of the sponsor: None.
- [1] H. O'Donnell, C. Parker. What is low-risk prostate cancer and what is its natural history?. World J Urol. 2008;26:415-422
- [2] M.R. Cooperberg, J.W. Moul, P.R. Carroll. The changing face of prostate cancer. J Clin Oncol. 2005;23:8146-8151
- [3] A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, M.J. Thun. Cancer statistics, 2009. CA Cancer J Clin. 2009;59:225-249
- [4] C.J. Savage, H. Lilja, A.M. Cronin, D. Ulmert, A.J. Vickers. Empirical estimates of the lead time distribution for prostate cancer based on two independent representative cohorts of men not subject to prostate-specific antigen screening. Cancer Epidemiol Biomarkers Prev. 2010;19:1201-1207
- [5] P.C. Albertsen, J.A. Hanley, J. Fine. 20-year outcomes following conservative management of clinically localized prostate cancer. JAMA. 2005;293:2095-2101
- [6] P.J. Bastian, B.H. Carter, A. Bjartell, et al. Insignificant prostate cancer and active surveillance: from definition to clinical implications. Eur Urol. 2009;55:1321-1332
- [7] M.A. Dall'Era, M.R. Cooperberg, J.M. Chan, et al. Active surveillance for early-stage prostate cancer: review of the current literature. Cancer. 2008;112:1650-1659
- [8] L. Klotz. Active surveillance for favorable risk prostate cancer: rationale, risks, and results. Urol Oncol. 2007;25:505-509
- [9] E.Z. Neulander, R.C. Duncan, R. Tiguert, J.T. Posey, M.S. Soloway. Deferred treatment of localized prostate cancer in the elderly: the impact of the age and stage at the time of diagnosis on the treatment decision. BJU Int. 2000;85:699-704
- [10] A.V. D'Amico, R. Whittington, S.B. Malkowicz, et al. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA. 1998;280:969-974
- [11] A.M. Nieder, M.S. Soloway. It's not a radical prostatectomy, it's a total prostatectomy. Eur Urol. 2008;54:715-716
- [12] J.C. Cappelleri, R.C. Rosen. The Sexual Health Inventory for Men (SHIM): a 5-year review of research and clinical experience. Int J Impot Res. 2005;17:307-319
- [13] K. Avery, J. Donovan, T.J. Peters, C. Shaw, M. Gotoh, P. Abrams. ICIQ: a brief and robust measure for evaluating the symptoms and impact of urinary incontinence. Neurourol Urodyn. 2004;23:322-330
- [14] S. Roemeling, M.J. Roobol, M.W. Kattan, T.H. van der Kwast, E.W. Steyerberg, F.H. Schroder. Nomogram use for the prediction of indolent prostate cancer: impact on screen-detected populations. Cancer. 2007;110:2218-2221
- [15] R.M. Martin, D. Gunnell, F. Hamdy, D. Neal, A. Lane, J. Donovan. Continuing controversy over monitoring men with localized prostate cancer: a systematic review of programs in the prostate specific antigen era. J Urol. 2006;176:439-449
- [16] G. Ploussard, E. Xylinas, L. Salomon, et al. The role of biopsy core number in selecting prostate cancer patients for active surveillance. Eur Urol. 2009;56:891-898
- [17] R.C.N. van den Bergh, S. Roemeling, M.J. Roobol, et al. Outcomes of men with screen-detected prostate cancer eligible for active surveillance who were managed expectantly. Eur Urol. 2009;55:1-8
- [18] A. Rajinikanth, M. Manoharan, C.T. Soloway, F.J. Civantos, M.S. Soloway. Trends in Gleason score: concordance between biopsy and prostatectomy over 15 years. Urology. 2008;72:177-182
- [19] F.H. Schröder, M.J. Roobol, T.H. van der Kwast, R. Kranse, C.H. Bangma. Does PSA velocity predict prostate cancer in pre-screened populations?. Eur Urol. 2006;49:460-465 discussion 465
- [20] M.F. O'Brien, A.M. Cronin, P.A. Fearn, et al. Pretreatment prostate-specific antigen (PSA) velocity and doubling time are associated with outcome but neither improves prediction of outcome beyond pretreatment PSA alone in patients treated with radical prostatectomy. J Clin Oncol. 2009;27:3591-3597
- [21] A.R. Helgason, J. Adolfsson, P. Dickman, M. Fredrikson, S. Arver, G. Steineck. Waning sexual function—the most important disease-specific distress for patients with prostate cancer. Br J Cancer. 1996;73:1417-1421
- [22] M.S. Soloway, C.T. Soloway, S. Williams, R. Ayyathurai, B. Kava, M. Manoharan. Active surveillance; a reasonable management alternative for patients with prostate cancer: the Miami experience. BJU Int. 2008;101:165-169
- [23] K.S. Tseng, P. Landis, J.I. Epstein, B.J. Trock, H.B. Carter. Risk stratification of men choosing surveillance for low risk prostate cancer. J Urol. 2010;183:1779-1785
- [24] S.B. Zeliadt, S.D. Ramsey, D.F. Penson, et al. Why do men choose one treatment over another?: a review of patient decision making for localized prostate cancer. Cancer. 2006;106:1865-1874
- [25] K. Fujita, P. Landis, B.K. McNeil, C.P. Pavlovich. Serial prostate biopsies are associated with an increased risk of erectile dysfunction in men with prostate cancer on active surveillance. J Urol. 2009;182:2664-2669
Department of Urology, Miller School of Medicine, University of Miami, Miami, Florida, USA
Corresponding author. Department of Urology, University of Miami Miller School of Medicine, PO Box 016960 (M-14), Miami, Florida 33101, USA.
Please visit www.eu-acme.org/europeanurology to read and answer questions on-line. The EU-ACME credits will then be attributed automatically.
Article information
DOI: 10.1016/j.eururo.2010.08.027
© 2010 European Association of Urology, Published by Elsevier B.V.


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This Just In ...
Kevin Fischer is a veteran broadcaster, the recipient of over 150 major journalism awards from the Milwaukee Press Club, the Wisconsin Associated Press, the Northwest Broadcast News Association, the Wisconsin Bar Association, and others. He has been seen and heard on Milwaukee TV and radio stations for over three decades. A longtime aide to state Senate Republicans in the Wisconsin Legislature, Kevin can be seen offering his views on the news on the public affairs program, "InterCHANGE," on Milwaukee Public Television Channel 10, and heard filling in on Newstalk 1130 WISN. He lives with his wife, Jennifer, and their lovely young daughter, Kyla Audrey, in Franklin.
StunningThat was the word one of the speakers at today's Sendik's opening in Franklin, I believe it was Franklin Mayor Tom Taylor, used to describe the architecture of Sendik's and the adjacent Target, set to open July 23. You can see a picture of Sendik's in Senator Mary Lazich's blog.
The buildings do look great at the Shoppes at Wyndham Village, off to a very good start with lots of movement and activity.
This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.


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The eyebrow plays an important role in facial harmony and eye protection. Eyebrows can be injured by burn, trauma, tumor, tattooing and alopecia. Eyebrow position, contour, and movement are important features of facial expression. There are some really nice tips on "shaping your eyebrow" here. Many of those tips can be used in reconstructing an eyebrow. I particularly like these:
- Go with the natural line of your eyebrow. All bone structure is different, and so are your eyebrows. Not sure where your eyebrows should be? Run your finger along your eyebrow bone. That's exactly where the line of your eyebrow should be. If you try to arch your eyebrows too high above the bone, it will look too fake. Stay with the arch that works best with your bone structure. It's the one that you naturally have already.
- Make sure the beginning and end of the eyebrow is on the same line. If one side is too high up or too far down, it can throw off the shape of the eye.
- The goal of perfect eyebrows?
To bring attention to your beautiful eyes, not your eyebrows.
The pictures here illustrate how important brows are to how our face looks. The first is pre-transplantation and the second post. To me it is a dramatic difference.
Eyebrow Anatomy and Physiology
The density of eyebrow hair generally remains stable with age. Men often have an increased number of eyebrow hairs than women. The eyebrow is frequently altered in appearance by plucking.
There are four very distinct characteristics of eyebrow hair:
- The direction of eyebrow hair changes dramatically in different parts of the brow. In the region of the eyebrow nearest the nose, the hair points upward, almost vertical in orientation. The hair across the top of the eyebrow points outward and downward. The hair in the lower part of the brow grows outward and upward.
- The hairs of the eyebrow emerge from the follicle at a very acute angle so that the hair grows flat to the skin's surface. This is in contrast to scalp hair where the angle between the hair and scalp can be 45 degrees.
- The hairs grow as individual strands, rather than in the 1- to 4-hair follicular unit grouping that are characteristic of scalp hair.
- The growth cycle of eyebrow hair is very short. This means that eyebrow hair will grow (in anagen) only for about 4 months before it enters the resting (telogen) phase and falls out. In contrast, scalp hair has a growth phase that can last 3 to 7 years, enabling the scalp hair to grow much longer.
Methods for Eyebrow Reconstruction include:
- Hair Transplant Grafting -- It is important to follow the natural hair direction very closely. This entails very subtle angle changes to recreate the fan-like splay of hair at the medial end of the brow and the converging hair direction as one moves laterally along the brow. You want the hair will lie as flat as possible on the surface of the skin as it grows so the recipient sites have to be created at very acute angles to the skin surface. Only individual hair follicles should be used. If the patient's hair is waved or curly, it is important to rotate the hair so that curve of the hair shaft follows the natural curve of the eyebrow. (photo shows brow immediately after grafting) The hair transplanted to eyebrows will continue to grow and must therefore be periodically cut. This leaves a cut-end that is not as delicate as the fine-tipped end of an untouched hair. In the process of healing, all wounds contract. This may slightly change the hair's flat orientation and result in eyebrow hair that is slightly more elevated than one would like. Over time, the transplanted scalp hair will slowly begin to approximate the growth pattern and characteristics of the existing eyebrow hair, but may never totally match it. The appearance of eyebrow hair transplants will mature over the course of a year. During this interval, the eyebrow can be tweezed and shaped as needed.
- Superficial temporal artery island flap with anterior or posterior branch -- There are two draw backs for use of this flap--1) the frontal area is a common site of hair loss in men and this can affect the reconstructed brow and 2) the hair will grow downward when placed in the brow position
- Island flap from lateral parietal area -- This area of scalp is not usually affected by alopecia. This flap used the superficial temporal artery. The hair will grow in the correct direction, sort of (see above on the complex changes of direction of eyebrow hairs). Care must be taken so that when the flap goes through the cutaneous tunnel of the temporal area, there is no torsion or tension.
The complications will depend on what procedure is done. For each there is always the risk of infection, bleeding, and scar (donor site and brow site). For the flap techniques, there is the risk of loss (partial or complete) of the flap to necrosis. To each, there is the possibility of a poor result.
And though most of us don't wish to have Groucho Marx eyebrows, you must admit the way he "wiggles" them can make you laugh. Check him out in this scene from "Monkey Business"
Comparison of Four Surgical Methods for Eyebrow Reconstruction; Indian Journal of Plastic Surgery, Vol 40, #2, pp 147-152, 2007; Omranifard Mahmood, Koushki A Mehrabi
EYEBROW TRANSPLANTS -- From Scalp to Brow; Plastic Surgery Products 2006; 34-8; William R. Rassman, M.D. and Robert M. Bernstein, M.D.
Eyebrow Reconstruction; Plastic & Reconstructive Surgery, 107(5):1225-1228, April 15, 2001; Juri, Jose M.D.
Reconstruction of ear, eyebrow, and sideburn in the burned patient; Plast. Reconstr. Surg. 55: 312, 1975; Brent B
Reconstruction of the Localized Eyebrow Defect; Plastic & Reconstructive Surgery. American Society of Maxillofacial Surgeons 50th Anniversary. 100(3):685-689, September 1997; Cedars, Michael G. M.D.
Aesthetic Analysis of the Eyebrows; Plastic & Reconstructive Surgery. 99(7):1808-1816, June 1997; Gunter, Jack P. M.D.; Antrobus, Steve D. M.D.
Eyebrows--Oculoplastic Gallary
The Model Eyebrow by Elle von Frendenberg; The Beauty Newsletter(blog), November 8, 2006
Anatomy of 'A Beautiful Face & Smile'; J Anat. Soc. India 52(1) 74-80 (2003); Patnaik, V.V.G; Singla Rajan, K; Bala Sanju.


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Schizophrenia Quiz: What is Schizophrenia?
Reviewed by Melissa Conrad Stöppler, MD on January 28, 2011
Images provided by:
1. iStockphoto
2. iStockphoto
3. iStockphoto
4. iStockphoto
5. iStockphoto
6. iStockphoto
7. iStockphoto
8. iStockphoto
9. iStockphoto
10. iStockphoto
WebMD: Mental Health and Schizophrenia
NIMH: What is schizophrenia?
MedicineNet: Schizophrenia
WebMD: Schizophrenia Types and Symptoms
WebMD: Schizophrenia Cause
<http://www.webmd.com/schizophrenia/tc/schizophrenia-cause >
NIMH: What are the symptoms of schizophrenia?
<http://www.nimh.nih.gov/health/publications/schizophrenia/what-are-the-symptoms-of-schizophrenia.shtml >
WebMD: Schizophrenia – What Happens
This tool does not provide medical advice. See additional information:
THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the MedicineNet Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.
© 1996-2017 MedicineNet, Inc. All rights reserved.


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|Posted by Terry Love on March 26, 19101 at 11:21:14:
|In response to Re: How do you make a loop vent.
: There are at least three ways to make a loop vent. Usually only one of them is approved in any given area. Your building inspection department normally will have a sheet showing how they want it done.
hj is right.
: : Where can I find information on how to construct a loop vent? Do the DIY books cover this?
|Replies to this post
|There are none.


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When something bad happens, you have three choices: let it define you, let it destroy you, or let it strengthen you.
The heart of the difference is not ability or even talent, but desire
The purpose of life is to discover and develop your gift. The meaning of life comes from sharing your gift with others. - David Viscott
Monday, January 31, 2011
6 years later...
13 comments:
It's fun to mix it up a bit, eh? After all, FUN is what it's all about. ;-) NICE! on the even splits, too!ReplyDelete
Nice job Olga! Way to get outside of your comfort zone and still run a rockin' race!ReplyDelete
Every now and then I think about doing another road marathon (I've only done one). Then I remember how much they hurt! I'll stick to long, slow, mountains and such...
Awesome job lady!!!ReplyDelete
You are hiking the Continenal Divide Trail up here I hope! Awesome work on the Marathon. You are awesome!ReplyDelete
That course was crazy with hills! You did awesome! Bike, swim? Um, is there something I don' know? You planning on going from an ultra-babe to a tri-babe? ;)ReplyDelete
Nice job, roadie!ReplyDelete
Oooo a road marathon. Good for you. It ended up being a tough but satisfying say. Sounds like that running high lasted awhile too.ReplyDelete
What a fun race report Olga! I smiled the whole time I read it! Thanks for posting it.ReplyDelete
Glad to hear you mixing it up. 27 miles would be nothing more than a semi long run for you, but when you're on a hard surface, harder pace, and higher heart rate, it becomes very respectable. Great effort and results on a hilly course! Looks like you really dialed in your salt and water needs. I will miss RR this year, and what a strong field to watch, but will be looking forward to the next one.ReplyDelete
"but my excuse is that my races should never stand in a way of me having fun in other life's pursuits. So, sore or not, I was ready for a test..." I love it! It's hard core. Great job on the marathon....way to hang in there on the pavement.ReplyDelete
So awesome Olga, Great job on the race and bust out that pavement. It's almost harder than a tough 50M :)ReplyDelete
Way to go, Olga! I love your positive spirit. Very inspiring!ReplyDelete
Very cool Ms Olga! I knew you had 26 miles of speed in you somewhere. Gail is looking over my shoulder and says "Hi, we miss you!"ReplyDelete


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Girls Are All Sunshine & Sweetness
August 1st, 2014
They say a smile can light up a room, but lets face it, if it also comes with an epic package like this then it's time to put on your darkest shades and apply copious amount of sun-screen because these ladies are so hawt they will burn you!
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Articles like this really gesrae the shafts of knowledge.
That rlealy captures the spirit of it. Thanks for posting.
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Yo, good lokoin out! Gonna make it work now.
Always a good job right here. Keep rollnig on through.
I wanted to spend a mnitue to thank you for this.
Love yr website, but am wondering if you can make it so that you can see easier what page number you're on, such as highlight the number. Cheers!
who is that blonde girl on the right in pic #6?
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text: Should I Upgrade to Mountain Lion?Alan Henry7/25/12 10:00amFiled to: Ask LifehackerOs Xmountain lionMac OSMacUpgradesQuestionsFeatures10.8SupportprosconsNews54EditPromoteShare to KinjaToggle Conversation toolsGo to permalink Dear Lifehacker, Mountain Lion is out, and I'm seeing it has some pretty cool new features! Should I upgrade? Signed, Eager Beaver Advertisement Advertisement Dear Eager, Good question! OS X 10.8 Mountain Lion is hot off the presses, and you're right—it does include some really interesting new features. Whether you should upgrade, however, depends on a couple of things, most notably what kind of Mac you have, the applications you run, and how you interact with your computer. It's a cheap upgrade, no doubt, coming in at $19.99, and that alone may be convincing enough reason to upgrade, but let's look at the pros and cons first. First, Check If Your Mac Can Support Mountain LionBefore you whip out the credit card, you should make sure your Mac can even support the upgrade—many Macs that you may have thought would be able to upgrade actually can't, so tread carefully. We tackled the basic system requirements in our guide to prepping your Mac for Mountain Lion, but if you missed it, here's what you'll need: Apple's general system requirements are: Sponsored OS X v10.6.8 (Snow Leopard) or later2GB of memory8GB of available spaceApple also lists which models support Mountain Lion: Advertisement Advertisement iMac (Mid 2007 or newer)MacBook (Late 2008 Aluminum, or Early 2009 or newer)MacBook Pro (Mid/Late 2007 or newer)Xserve (Early 2009)MacBook Air (Late 2008 or newer)Mac mini (Early 2009 or newer)Mac Pro (Early 2008 or newer)To find out what model of Mac you have, clicking the Apple in your menubar, select "About this Mac" and click "More Info..." You'll see your Mac's model and release date, as well as the amount of memory installed to compare with the basic requirements. (Click the Storage tab to see if you have enough free space.) Hackintosh users should check Tonymac's blog post on getting ready for Mountain Lion for notes about additional requirements or potential issues.If your Mac won't support Mountain Lion, never fear: there are ways to get the best features in Lion, right now. Next, Check If Your Apps Will Run in Mountain LionThe vast majority of your apps will likely run in Mountain Lion, without any special updates or tweaks. Developers have had a long time to work on updates, and in our testing, even some of the beefier, more problematic applications like Photoshop work flawlessly. If you have a favorite OS tweaking tool however, that may need to be updated before its compatible with Mountain Lion. Head over to RoaringApps' Comatibility Checklist to see if your most frequently-used programs are supported.What Version of OS X Are You Running Now?If you're running Lion, Mountain Lion won't feel like a huge bump to you. Some of the new features, like Notification Center, will make themselves known right away, and that's great—but a lot of the other features, like Twitter and Facebook integration, will probably never occur to you unless you go looking for them. Behind the scenes features like Power Nap and Auto Save will definitely save you time and hassle, but you may not even know they're there. If you're still running Snow Leopard, on the other hand, Mountain Lion will probably be a bigger jump for you—one that will come with many more features to explore, and considering it's only $20 to skip over Lion and get everything it comes with too, it's hard to say no.Are There Features Are You Looking Forward To?Apple boasts over 200 new features in Mountain Lion, but the ones you're most likely to notice are a bit more front and center. Let's consider some pros and cons about those new features and utilities: Advertisement Advertisement Pros: As Apple rolls in core features that used to be former apps, they get better. For example, if you love Growl you'll probably love Notification Center. Notification Center brings in system-wide alerts, makes them always viewable in a side panel, organizes them so they're easy to sift through, and even includes apps that weren't very Growl-friendly.If you're wedded to the Apple ecosystem, the new cloud and messaging features will fit right in. Even if you already use Dropbox or Google Drive, iCloud's new document sync will work for you—it's seamless and in the background. If you and your friends all use iMessage, the ability to get and send those messages right from your Mac will probably appeal to youMountain Lion brings new utilities that make working with your computer easier. Apple's Power Nap, which updates your system, does backups, and syncs your documents and files to iCloud in the background while your Mac is sleeping, is a great feature. Dictation, which allows you to speak to your Mac in an almost Siri-like manner to open app and work on documents, can change the way you work with your system.Cons: Many Mountain Lion features are already available. The best features, like iCloud syncing, notifications, auto-save, notes, and reminders, are all already available in other apps that do the same things, and in many cases (Notes and Reminders, for example) those other apps do it much better. Advertisement None of Mountain Lion's features are really revolutionary: Mountain Lion definitely has a lot of features, but few of them are really "can't live without" features or utilities. Like we said, If you skipped over Lion and are still running Snow Leopard, you it'll be a big jump, but if you're running Lion, you really won't feel like you're running a whole new OS. The Verdict: Do You Have $20 to Spare?At the end of the day, if you have $20 to spend, we can't argue against getting Mountain Lion. If you see some of the features in Mountain Lion and think "that'd be pretty awesome to have," or "I'll definitely use that," then upgrade without delay. If you're still on Snow Leopard, it's a good upgrade for you. It's affordable, solid, stable, and a really quick install—it only took me about 30 minutes, and afterward all of my apps worked without issue. Advertisement At the same time, if you already have Lion and you don't see what the fuss is about, or like your Mac the way it is, you may want to hold off, mostly because odds that you'll be somehow surprised by something in Mountain Lion that'll make you say "I'm glad I have this," are pretty slim. Plus, there are ways to get the best Mountain Lion features in Lion already, even if they're not as well integrated or supported by Apple.Love, Lifehacker Advertisement Have a question or suggestion for Ask Lifehacker? Send it to firstname.lastname@example.com repliesLeave a reply


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神秘来电:双生之谜: Walkthrough Guide, Tips and Tricks
By: zhong zhi bin
Welcome to the walkthrough for 神秘来电:双生之谜 on iOS and Android. The walkthrough contains the solution and will guide you through each of the levels with gameplay tips, tricks, hints and cheats, to enjoy 神秘来电:双生之谜 game on your iPhone, iPad and Android devices. Here, you'll have exclusive access to walkthroughs videos, level guides, missions, as well as a discussion section for each of the levels.
We provide a community for gamers to discuss, learn and share anything about 神秘来电:双生之谜. Anyone can join in, share their experience and tips with others. If you have any questions, request or need extra help; feel free to ask by making a comment.
The 神秘来电:双生之谜 game app is developed by zhong and available on iTunes and Google Play. For more details on the app, check out our review.
- App name: 神秘来电:双生之谜
- Seller: zhong
- Category: Adventure
- Updated: Jan 14, 2016
Until the Walkthrough is completed, feel free to ask for help in the comments section.
Get Help and Join the Community
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Gibson and Cole reds rescinded
West Ham striker Carlton Cole tonight vowed to "make all the aggro worth it" after a successful appeal against the red card he received in last Saturday's home Premier League defeat by West Ham.
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Everton and West Ham both won challenges on Thursday against dismissals, with the Toffees seeing Darron Gibson's punishment wiped out.
Cole was sent off by referee Anthony Taylor in the 67th minute for a high tackle on Leighton Baines which was determined to be dangerous.
It came soon after his opening goal was matched by an equaliser from Victor Anichebe, and Everton went on to take all three points thanks to a Steven Pienaar goal six minutes later.
West Ham succeeded with their case at a Football Association hearing, meaning Cole will be available for Saturday's Premier League match against Reading.
Cole wrote on Twitter: "Great news that the red card got overturned, @FA done a great job. Well done! Time to make all the aggro worth it on Saturday if selected!"
While Cole was ordered off midway through the second half, Everton midfielder Gibson followed in stoppage time for a similar tackle on Mark Noble during Everton's 2-1 win.
Everton lodged their appeal with the FA on Christmas Eve, meaning Gibson was able to face Wigan on Boxing Day, and he will now be available to manager David Moyes for Sunday's game against Chelsea and beyond.
A statement from the FA said: "The FA can confirm that red cards shown to both Carlton Cole and Darron Gibson have been rescinded.
"Both players were sent from the field of play in the Premier League fixture between West Ham United and Everton at Upton Park on Saturday 22 December.
"Their three-match suspensions have been withdrawn immediately and written reasons will be provided at a later date."
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Kenneth Cole Reaction On The Gleam Girls Toddler & Youth Dress Shoe
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Item # 271564
These Girls on the Gleam Kenneth Cole Reaction Mary Jane shoes will "Dress Up" your little ones' look instantly. Style on their own with dresses in the summer or layer on fun tights to give her outfit a different look.
- Faux leather upper
- Adjustable Mary Jane strap for fit
- Padded footbed
- Synthetic traction sole
- Imported
- Online Exclusive!
Tell us what you think!
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Color Me Coppens
Tim Coppens presented a Spring 2013 collection of streamlined, masterfully detailed pieces—fresh and honestly beautiful things, the kind that stroke my sense of wonder about fashion. He continued his story of luxe-tech, this season inspired by the swagger of post-World War II fighter pilots and the early icons of Detroit's techno music scene, enlivened with a note of optimism with the introduction of a 50′s to early 60′s modernist color palette and graphic design elements. In a city hampered by the economy, continually belaboring images of the past, he brought a sense of integrity with designs that are fresh and exciting and expertly executed; Coppens was a tough act to follow.
The colors were not accent colors, not full-on color, not dark, not pastel, not primaries. In fact, the show wasn't about the color palette; the colors served only to expound on the harmonious design that made the clothes sing.
Says the color-averse dandy to this collection, "Color Me, Coppens."
photographs by Sophia Callahan and Izzy Tuason
5 Comments
I absolutely loved what I saw of this show. Normally I don't get that excited about what comes out of New York – it tends to err too much on the commercial side for my liking. But this collection struck just the right balance. From the runway shots I particularly liked the jackets and sweaters with differently coloured arms, but seeing these close-ups I'm also a fan of the quilted shorts and bags! Such great details on all the pieces.
Although I personally am not a fan of tech or futuristic pieces, I would say that the execution of the pieces is impeccable. I love the modern silhouette. The colours a bit too gloomy for spring though, not that Dior Homme did anything about it too. Nice shots of two of my all time favorites Charlie France and Baptiste Radufe.
'Tech-sexy harness' is my new greatest aspiration
love seeing the details, seems like a collection I'd like to shop!


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De Blossom Collection Livia-1 Wedge Sandal
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Item # 276178
Strappy and chic, the Livia-1 wedge sandal from DeBlossom is the perfect summer staple for your warm-weather style.
- Strappy patent upper
- Heel strap with adjustable buckle
- 1½" platform, 4¾" cork wedge heel
- Synthetic sole
- Imported
By: kotex9
Location: austell, ga
May 31, 2013
"nice and sexy, but my straps had come out, after one use"
By: TLD01
Location: Plano, TX
May 15, 2013
Too Cute!
"These shoes are so comfortable and I receive so many compliments every time I wear therm! If you need a red sandal -- order these -- you won't be disappointed!"
By: ampina8279
Location: Arizona
April 25, 2013
sexy black sandal
"great height and very sexy"
By: BJRome
Location: El Paso
April 04, 2013
Love Love Love
"Loved my shoes, fit perfect!!!!"
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