text:
Age-related accumulation of T cells with markers of relatively stronger autoreactivity leads to functional erosion of T cells
© Tatari-Calderone et al; licensee BioMed Central Ltd. 2012
Received: 1 November 2011
Accepted: 9 February 2012
Published: 9 February 2012
Thymic involution is a prominent characteristic of an aging immune system. When thymic function is reduced/absent, the peripheral T cell pool is subject to the laws of peripheral T cell homeostasis that favor survival/expansion of T cell receptors with relatively higher functional avidity for self-peptide/MHC complexes. Due to difficulties in assessing the TCR avidity in polyclonal population of T cells, it is currently not known whether high avidity T cells preferentially survive in aging individuals, and what impact this might have on the function of the immune system and development of autoimmune diseases.
The phenotype of T cells from aged mice (18-24 months) indicating functional TCR avidity (CD3 and CD5 expression) correlates with the level of preserved thymic function. In mice with moderate thymic output (> 30% of peripheral CD62Lhi T cells), T cells displayed CD3lowCD5hi phenotype characteristic for high functional avidity. In old mice with drastically low numbers of CD62Lhi T cells reduced CD5 levels were found. After adult thymectomy, T cells of young mice developed CD3lowCD5hi phenotype, followed by a CD3lowCD5low phenotype. Spleens of old mice with the CD3low/CD5hi T cell phenotype displayed increased levels of IL-10 mRNA, and their T cells could be induced to secrete IL-10 in vitro. In contrast, downmodulation of CD5 was accompanied with reduced IL-10 expression and impaired anti-CD3 induced proliferation. Irrespective of the CD3/CD5 phenotype, reduced severity of experimental allergic myelitis occurred in old mice. In MTB TCRβ transgenic mice that display globally elevated TCR avidity for self peptide/MHC, identical change patterns occurred, only at an accelerated pace.
These findings suggest that age-associated dysfunctions of the immune system could in part be due to functional erosion of T cells devised to protect the hosts from the prolonged exposure to T cells with high-avidity for self.
Immune system of elderly displays complex set of changes relative to young individuals. Of the many variations observed, altered T cell function is the most consistent and most dramatic one [1]. Despite relatively normal numbers of CD4+ and CD8+ lymphocytes, T-cell dependent functions of the immune system of aged individuals are defective, as evidenced by reduced DTH reactions and antibody production in response to vaccination and infection [2]. This could be due to reduced proliferation of T cells, evident at biochemical level by defects in proximal TCR signaling cascade activation [3–5] and calcium signaling [6], and at cellular level by defects in cytokine production [7] and differentiation to Th1 or Th2 effector cells [8]. In addition, the frequency of antigen-specific naive T cells is reduced, due to an impaired production of T cells caused by thymic involution [9]. Reduction of the thymus size and cellularity generally starts in puberty [10] and is thought to reflect depletion of thymic stromal tissue [11], as well as thymus repopulation by bone marrow derived precursors [12].
The lower supply of naive T cells leads to a shift in the balance between memory and naive T cells, with overrepresentation of the former [3]. This is due to transitioning of the naive into the memory T cells following activation with antigen, but also in response to the laws of T cell homeostasis. The peripheral T cell pool is maintained by production of new T cells by the thymus, and homeostasis-driven expansion of peripheral T cells [13]. If the function of thymus is reduced, the numbers of T cells are maintained by a compensatory increase in homeostatic expansion [14, 15]. The extent of homeostatic expansion of any given T cell is dependent on the functional avidity of the TCR for self-peptide/MHC complexes [16–18]. One would therefore predict that the peripheral repertoire of T cells would skew towards high avidity T cells sometime following age-associated thymic involution. This issue, however, has not been addressed to date, due to difficulties in assessing the TCR avidity in polyclonal population of T cells. T cells constantly tune their sensitivity to self-peptide/MHC complexes by changing the levels of TCR/CD3 and CD5 molecules [19–21]. The letter is an inhibitor of TCR signaling [22], and T cells perceiving strong signals up-modulate CD5 to reduce signaling and avoid over-stimulation. Similar impact is achieved by down-modulating CD3, producing a CD3loCD5hi phenotype. Converse phenotypic changes occur if surrounding signals are perceived weak- T cells increase their sensitivity by up-regulating CD3 levels and down-modulating CD5, producing a CD3hiCD5lo phenotype. Thus, CD3 and CD5 levels can serve as indicator of the strength of signal perception by T cells, and if the levels of self-peptide/MHC are constant, the major determinant of the signal magnitude generated is the affinity/avidity of the TCR for self-peptide/MHC complexes. Taking advantage of the fact that levels of CD5 and TCR/CD3 expression can be used to predict relative TCR avidity [21], we have shown that relative levels of these two molecules could be used as markers of overall avidity of the TCR repertoire [23].
The avidity of TCR for antigen is considered an important characteristic of an efficient T cell-mediated immunity [24]. Protection against tumors or infectious agents by monoclonal (or oligoclonal) T cell populations correlates with the avidity of the TCR for given antigen [25, 26]. However, increase in the avidity to foreign antigens also elevates the avidity to self-peptide/MHC complexes [27], likely due to cross-reactivity between cognate antigen and self-peptides that promote selection and homeostasis of T cells [28]. As with foreign antigens, higher avidity for auto-antigens leads to more severe autoimmunity [29–32]. Furthermore, high avidity TCR engagement with self peptide/MHC molecules may induce both cell intrinsic and extrinsic compensatory mechanisms [33], rendering it impossible to predict the net effect of high avidity TCR recognition on the function of a polyclonal immune system. We here show that CD3/CD5 phenotype of T cells undergoes a two-phase change in aged, as well as mice subjected to adult thymectomy. Increased CD5 and reduced CD3 levels in the first phase are consistent with preferential survival of high-avidity T cells, while the second phase was characterized by a drop in CD5 levels. The latter change appears to be a part of a shut-down of T cell function, that followed a period with increased production of IL-10. We speculate that this may be an attempt to counteract the preferential survival of high avidity T cells due to their potential to induce stronger autoimmune responses.
Dynamics of peripheral T cell CD3 and CD5 levels in the function of thymic export
Distinct functional phenotypes of T cells from type A- or type B- old mice
Reduced T cell responses of old mice in vitro and in vivo
Age related changes in T cells are accelerated in mice with increased avidity for self
Defective responses of T cells with down-modulated CD5 could be a result of increased propensity for activation induced cell death. We therefore compared the levels of apoptosis following anti-CD3 stimulation. Reduced levels of apoptosis were observed in MTB relative to the WT T cells (Figure 7B), suggesting that activation induced cell death is not a likely cause of reduced T cell responses in T cells with decreased CD5 levels.
To determine whether the hyporesponsiveness is due to general inability of T cells to respond or due to TCR signaling defect, we subjected T cells to pharmacologic stimulation consisting of phorbol esters and ionomycin, that by-passes the most proximal TCR signaling. The results show relatively similar potential of cells to respond to this stimulation (Figure 7C), suggesting that the cause of hyporesponsiveness is related to the CD3/TCR complex-mediated signal transduction.
Our findings demonstrate that following a shortage in supply of newly developed T cells due to thymic involution, peripheral T cell compartment in aged mice displays a sequence of phenotypic and functional changes important for the functioning of the entire immune system. These changes follow a characteristic pattern. The first phase was predictable by the known effects of T cell homeostasis in lymphopenic conditions and the effect of the functional avidity of the TCR on peripheral T cell homeostasis. In this phase, there was an increase of both CD4+ and CD8+ T cells with a phenotype (CD3lowCD5hi) indicative of relatively higher functional avidity for self-peptide/MHC complexes [21]. The second phase is characterized by development of functional erosion of T cells, caused by a defect in TCR-mediated activation.
Self-peptide/MHC complexes are involved in many aspects of T cell physiology, promoting thymocyte differentiation [38, 39], enabling peripheral survival and homeostasis of naïve T cells and modulating their activation by antigens [40–42]. Under lymphopenic conditions residual T cells proliferate to reconstitute their nearly normal numbers [41]. T cells with higher avidity for self-peptide/MHC complexes enjoy advantage and expand more relative to the low avidity T cells [16–18]. During and or consequent to the expansion process T cells acquire phenotype of activated/memory T cells and acquire effector functions [43–47]. In addition to the faster disappearance of T cells with naive phenotype, the accumulation of high avidity T cells and their partial activation is potentially dangerous due to increased risk of autoimmune disorders. In fact, lymphopenic conditions are known to be associated with autoimmune phenomena [48]. However, the incidence of autoimmune diseases in general does not increase in elderly, despite development of lymphopenia.
In humans, each autoimmune disease has a characteristic pattern of incidence. Although average peak of incidence differs for each individual autoimmune disease, a general trend suggests that most autoimmune diseases develop either during puberty (juvenile type diseases) or during mature reproductive life of individuals. For example, lupus erythematosus affects primarily women of childbearing age, and most frequently begins between ages of 15 and 40 years [49]. The average age of onset of multiple sclerosis is 28-30 years [50]. The number of new cases in both diseases, as well as other autoimmune diseases, reduces with further age. What could be the reason for this decline? The function of the immune system declines with aging in both mice and humans, limiting its ability to respond to infections and vaccines [2, 15]. The changes are mainly due to dysfunctions in the T cell compartment while the activity of B cells and innate immunity are less affected [2, 51]. However, these changes occur at age of 70 or higher, and are unlikely responsible for the decline in incidence of autoimmunity after the ages of 30-40. Our results showing attenuated clinical EAE in aged mice are in agreement with the incidence of human autoimmune disorders. Concomitant changes in T cell phenotype and function of old mice suggest that reasons for reduced autoimmunity may be intrinsic to T cells. This notion is further supported by an earlier occurrence of EAE attenuation in MTB TCRβ transgenic mice, since the transgene is expressed by T cells and hence affects primarily the function of T cells. Interestingly, we have previously shown an age-dependent arrest in the progression of lupus in F1 offsprings of MTB and lupus-prone BXSB strain [52]. This arrest was coupled with reduced activation of T cells in vivo and reduced numbers of natural regulatory T cells, suggesting again a mechanism intrinsic to T cells. The numbers and function of natural regulatory T cells in MTB mice on B6 background (used in the present study) are indistinguishable from the WT mice [23], arguing against the role of these cells in reduced susceptibility of MTB mice to EAE. It remains to be determined whether intrinsic mechanisms additional to the two identified here (increased IL-10 production and functional arrest) may be involved, such as possibly changes in IL-17 production- a cytokine important for development of EAE [53].
It is tempting to speculate that the strategy of the immune system to counteract age associated increased risk of autoimmunity is promotion of differentiation of T cells with a potential to secrete IL-10 (so called Tr1 cells). In support of this notion, development of multiple sclerosis in humans is associated with defective development of Tr1 cells that secrete IL-10 [54, 55]. IL-10 secretion as a result of chronic high-avidity TCR engagement has been described in other experimental models [34–37], and increased IL-10 production associated with aging has been reported in both aged mice [56] and humans [51]. Our results showing an earlier onset of IL-10 mRNA levels in mice with artificially higher TCR avidity for self-peptide/MHC complexes clearly supports this possibility, although this may not be the only mechanism affecting the function of the immune system in type A mice. Subsequent reduction, however, suggests that the control of enhanced T cell reactivity for self by IL-10 is temporary, and persisting chronic stimulation leads to a functional shut down.
Because IL-10-deficient mice develop enterocolitis [57], IL-10 is thought to be involved in maintenance of tolerance to self. However, IL-10 can also exert immunostimulatory properties, such as stimulation of B cell proliferation and differentiation into the antibody-secreting cells, and differentiation of CD8+ T cells into effector cells [58]. Despite these stimulatory functions of IL-10, the effect of IL-10 in most studies of autoimmune diseases is one of regulation. Thus in EAE, systemic administration of IL-10 prior to EAE induction prevents the development of the disease [59, 60]. In contrast to the actively induced EAE, injection of IL-10 exacerbated adoptively transferred form of the disease [61]. Removal of IL-10 by gene inactivation increases the severity of the disease [62–64], suggesting that IL-10-production has a physiological role in dampening the course of the EAE. In lupus, the levels of IL-10 found in the serum of affected patients correlate with the disease activity [65]. This could suggest involvement of IL-10 in the pathogenesis of the disease, but also (apparently unsuccessful) attempts of the immune system to regulate the ongoing autoimmune response. The former possibility is supported by ameliorating effects of anti-IL-10 antibody treatment in lupus patients [66], as well as in NZB hybrid mice [67]. However, these early results were countered with the findings of new studies. Thus, genetic deficiency of IL-10 resulted in significantly enhanced disease, while the treatment with recombinant IL-10 ameliorated the disease in the MRL model [68]. Furthermore, continuous low levels of IL-10 achieved by gene therapy approach also diminished the disease activity in NZB hybrid congenic mouse model [69]. Therefore, the exact role of IL-10 in lupus remains to be established.
T cell dysfunction resulting in progressive difficulties to raise immune responses have been described in elderly humans and mice [15, 70]. Therefore, these findings suggest that T cell dysfunctions associated with aging can at least partly be explained by adaptive alterations in high-avidity T cells caused by their autoreactivity. Our findings parallel those of tumor infiltrating T cells that become non-functional if their TCR is of high, but not low affinity for antigen [71]. Thus, while their immediate impact may be effective, high avidity T cells may not be most desirable for long-term protection and/or preservation of immunological memory, as they are likely to functionally erode earlier than the low avidity T cells.
Mice and in vivo manipulations
C57BL/6 mice were purchased from Taconic Farms (Germantown, NY). The generation of MTB TCRβ transgenic mice has been previously described [72]. All experiments using laboratory animals have been approved by the Institutional Animal Care and Use Committee.
For induction of EAE five mice per group were injected with an emulsion of MOG38-50 peptide ([73] solution in Complete Freund's adjuvant containing Mycobacterium tuberculosis, as described [74]. Mice also received 500 ng Pertussis toxin on days 0 and 2 relative to the encephalitogenic challenge. Mice were followed daily for clinical signs of the disease and were graded on the following basis: 0) no clinical signs; 1) flaccid tail; 2) hind limb paresis or partial paralysis; 3) total hind limb paralysis; 4) hind and front limb paralysis; and 5) moribund state or death.
Quantitative PCR
Total RNA was isolated from cells using TRIzol followed by RNAse clean-up and treatment with DNAse I. Total RNA was reverse transcribed using the Superscript II RT kit and random hexamers as primers (Invitrogen, Carlsbad, CA). All PCR reactions were done in triplicates using ABI Prism 7700 Sequence Detector (Applied Biosystems, Piscataway, NJ), as previously described [23]. Briefly, TCRβ, IL-10, and 18SrRNA were amplified using TaqMan Universal PCR master mix (Applied Biosystems). The average threshold cycles (Ct) of the triplicates was used to compare the relative abundance of the mRNA. Ct of 18SrRNA was used to normalize all samples.
Flow cytometry
Direct immunofluorescence staining was performed using following reagents: FITC conjugated anti-Vβ2, FITC- or APC-conjugated anti-CD5, FITC- or APC-conjugated anti-CD4, PerCP-conjugated anti-CD3, PE-conjugated anti-mouse CD8α, PE-conjugated anti-CD25 (all supplied by Pharmingen, San Diego, CA).
Cell purification
Spleen cells were purified using pan T cell purification kit (Miltenyi Biotec, Bergisch Gladbach, Germany). Microbead labeled cells were negatively selected on magnetic cell separation (MACS) columns (Miltenyi Biotec), as per manufacturer instructions. Cell purity was generally 92-97%, as determined by flow cytometry. Intracellular staining for FoxP3 was performed using the anti-mouse/rat FoxP3 staining kit from eBioscience (San Diego, CA).
In vitro stimulation assays
Spleen cells (2 × 105/well) were incubated for 72 hours in flat bottom 96-well plates in the presence of various concentrations of purified anti-CD3 monoclonal antibody. Irradiated (2500 rads) WT spleen cells served as antigen presenting cells in cultures with thymocytes (5 × 105/well), where indicated. During the last 8-16 hours of culture cells were pulsed with 0.5 μCi of 3H-thymidine (ICN Biomedicals, Costa Mesa, CA, USA) and thymidine incorporation was subsequently measured using a beta scintillation counter 1450 MicroBetaTM (Wallac, Turku, Finland).
AICD analysis
T lymphocytes from WT or MTB TCR transgenic mice were isolated from the spleen by negative selection (Pan T Cell Isolation Kit, Miltenyi Biotec). T cells (106/ml) were stimulated in vitro using CD3/CD28 beads (Dynabeads mouse CD3/CD28 T cell expander, Invitrogen) according to the manufacture's instruction. After 3 days, T cells were harvested and dead cells were removed by using gradient centrifugation. Viable T cells were then incubated for an additional 24 h with 10 U/ml recombinant mouse IL-2. For the secondary culture, T cells (5 × 105/ml) were restimulated with anti mouse CD3 beads. Cells were then harvested and stained with Annexin-FITC and Propidium Iodide-PE using Annexin V-FITC apoptosis detection kit II (BD Biosciences) and CD4-allophycocyanin (BD Biosciences) according to the manufacturer's instructions. Analysis was based on a CD4 cell gate. Data were collected on a FACSCalibur (BD Biosciences) and analyzed using CellQuest software.
Statistical analysis
Statistical significance of differences in the mean fluorescence intensities of CD5 and CD3 staining was calculated using Wilcoxon matched pairs test, performed using Graphpad Prism software, version 5.0a.
Experimental allergic encephalomyelitis
This work was supported in part by a grants from the National Institutes of Health; National Heart, Lung, and Blood Institute 1U54 HL090503 (ZT-C), and by 1R01 AI48837 and 1R01 AI41573 from the National Institute for Allergy and Infectious Diseases (SV).
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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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shingi_70 wrote:
sp i guess I'm in the middle of the ham. i just met the two spiry tree guys.
Beyond Good and Evil 2 better be happening! In the meanwhile though, here's a fun little Let's Play of the original. Think you'll like the game if you like Zelda!
LeT's PlAy BEYOND GOOD AND EVIL < Link to LP
3DS friend code: 2878 - 9709 - 5054
Nintendo Network ID: Slider...

subset: commoncrawl


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Enter the world of shopping with your very own pint-sized character! But be careful - once you shop, you cant stop! Each Shopkins is a super cute and fun character based on a different item of shopping. This super Shopkins pack contains 12 characters, a stackable display case as well as a collectors guide. But two of the characters are hidden. Will you be able to find them?
Check stock and price


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Is David Woolf the father of Melodie Woolf, the little girl he has just abducted from her Paris home? The fact that his last name is the same as hers makes his claim seem reasonable, and their passports cause no trouble for him when they cross the border. She is only half convinced, so she tries occasionally to escape, but not very hard. He has cut her hair to prevent any searchers from identifying her, so he could be a "regular" kidnapper. On the other hand, he had her call her mother. Melodie remains...more
All Mississippi One cast + crew photos


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Nike Skateboarding offers an alternative in the sneaker game to the heart covered other sneakers that are dropping for Valentines Day. The P-Rod 2 Zoom Air comes in a black/red colorway and is entitled "Valentine's Day Massacres". The title is translated onto the sneaker in the from of blood stains on the toebox and sides.
It will be released this week. After the jump more pictures.
Nike SB P-Rod 2 February '08 -"Valentine's Day Massacres"
What To Read Next


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Message view | « Date » · « Thread » |
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From | "Trustin Lee (JIRA)" <directory-...@incubator.apache.org> |
Subject | [jira] Updated: (DIR-120) Matrix comparison against other LDAP servers |
Date | Wed, 21 Dec 2005 07:37:31 GMT |
[ http://issues.apache.org/jira/browse/DIR-120?page=all ] Trustin Lee updated DIR-120: ---------------------------- Summary: Matrix comparison against other LDAP servers (was: Matrix comparizon) Fixed typo. Is there any existing feature matrix published other vendors so we can find out what features they compare? Otherwise, we could just create a new one based on Open Group LDAP certification requirements. > Matrix comparison against other LDAP servers > -------------------------------------------- > > Key: DIR-120 > URL: http://issues.apache.org/jira/browse/DIR-120 > Project: Directory > Type: Wish > Reporter: Emmanuel Lecharny > Priority: Minor > > A matrix comparizon between ApacheDS and OpenLdap could be a very cool thing to have. > Of course, the intention is just to give clues to users about which product bet suits their need, and to expose the gaps that we will need to fill to be a competitive product. > I don't think we can do that for other products, because of NDA we may be faced with (actually, I don't know if this is possible) -- This message is automatically generated by JIRA. - If you think it was sent incorrectly contact one of the administrators: http://issues.apache.org/jira/secure/Administrators.jspa - For more information on JIRA, see: http://www.atlassian.com/software/jira | |
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A tubby suburban dad watching hunting and adventure shows on TV and wondering could I do that? This is the chronicle of my adventures as I learn to learn to Forage, Hunt and Fish for food that has lived as I would wish to myself - Wild and Free.
Tuesday, 11 March 2014
Review The Sentry QAP1E Pistol Safe
Just arrived at the Lone Star branch office, this handy pistol safe was sent in by the lovely people at authoritysafes.com. Just the thing to prevent unauthorised fiddling.
I asked that well-armed man of the cloth the LSP for his first impressions
'tough, but discreet, and even a touch James Bond-ish.'
SBW: Not how do you see your job, how did you find the safe?
LSP: Same
The Authority guys also have a cracking deal on a big gun safe, thanks again chaps.
More soon
4 comments:
A rather "academic" review.
You'd never get a ticket for a s/a pistol here in the UK.
Wilf - 12 March 2014 at 09:48
- The Suburban Bushwacker said...
Are you feeling lonely?
SBW - 12 March 2014 at 17:15
Lonely?.....nope. Bored.....yep!
Wilf - 12 March 2014 at 17:28
- LSP said...
safe, all 'round.
- 21 March 2014 at 05:59
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London & Partners, the capital's new flagship tourism agency, will aim to position London as "the world's meeting place", according to interim chair, Dame Judith Mayhew Jonas.Speaking at the launch of the new organisation, she said: "We will focus on valuable business tourism and events ensuring that London is the leading destination for major sporting events, meetings and conferences. We will position London as the world's meeting place."She added that the CEO of London's international convention centre, ExCeL, was on the board and that it would become one of the great conference centres of the World.Mayor Boris Johnson said: "ExCeL is part of the vision we have for the Royal Docks; one of the new enterprise zones. There will be advantages for businesses to locate there."London & Partners brings together three of the capital's key promotional agencies – Visit London, Think London and Study London, which were previously responsible for attracting tourism, inward investment and international students. The funding for the new agency has been confirmed as an average of £14m per annum over the four-year spending review period, which represents a £3.35m decrease on the amount the three bodies received this year (Visit London's budget was £11.7m in 2010/11). However, dame Judith said the consolidated Normal 0 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} organisation would allow the London brand to be promoted in a "more coherent and joined up way" and enable them to work in partnership with the private sector.Grant Hearn, executive chairman of Travelodge and board member of London & Partners, said the tourism industry was relieved to have the new agency in place."I'd like to thank the mayor for rescuing it at a stage where we may not have an agency at all due to the budget cuts. I'm really excited about this new organisation. A single agency gives us that one strong voice and one point of contact for commercial partners to engage with."London & Partners will be led by interim chair Jonas and interim CEO Danny Lopez. Other board members include Jean-Louis Bravard, director of financial company Burnt Oak Partners, and Mike Thompson, senior vice president of commercial strategy at Glaxo SmithKline. More key appointments will be announced following a consultation period, which starts on Monday.Pictured: Mayor Boris Johnson


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Of course, anything that is posted is called a post.
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"I usually stick out my hand and hope he puts the ball in it. Except the one time I went to take him out. I stuck my hand out and he hit me right in the stomach with the ball." - Al Lopez
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Tom Morello Closes Out 'Orchid' Comic Book Series With a Saturday Signing in Anaheim!
Rage Against the Machine guitarist Tom Morello has been busy penning his Dark Horse Comics series Orchid since it debuted at San Diego Comic Con in July 2011. The twelve-issue run that centered on a dystopian theme described at the onset as "Lord of the Rings meets Battle of Algiers" comes to a close, but not before the rebel rocker visits Beach Ball Comics in Anaheim for a signing event!
Morello, who will be joined by Orchid illustratorScott Hepburn, has also recorded a score for the series. Beach Ball Comics tells the Weekly that rebel rocker isn't bringing a guitar with him to Anaheim on Saturday, though, just a signing pen. Either way, the soundtrack to Orchid will be playing at the store and the event is going to kick ass all the same! The weekend event will be a nice boost for the comic book store which suffered a break-in Tuesday with key, distinctive comics stolen from a display case. Anaheim police have apprehended a suspect and all but five comic books have since been recovered. In addition to the signing itself, Beach Ball Comics is also offering guaranteed backstage passes to a private after party with Morello and Hepburn for the first twenty people in line. Starting at 3 p.m., thirty other lucky fans will win the rest via raffle, so get there early! For everyone else, the two-hour signing itself is free and open to the public.
Orchid Signing and Wrap party with Tom Morello and Scott Hepburn at Beach Ball Comics, 3024 W Ball Rd Ste G, Anaheim. (714) 826-6127; Sat., 5-7 p.m. Free!
Follow us on Twitter @OCWeeklyMusic and like us on Facebook at Heard Mentality.
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Justice: 25/41 of 41
« back
10 groups campaigning for a healthier environment
19th June, 2009
How can we be healthy on a sick planet? Especially when many still believe that health is unaffected by what is in the environment. These organisations could save your life more...Campaigning against pirate fishing
Laura Sevier
22nd June, 2009
Illegally caught 'dirty' fish threatens local fishermen, consumer health and the future of the world's fisheries. The EJF's Pirate Fishing Campaign is tackling the problem head on more...Using the law to protect the environment
Andrew Wasley
19th June, 2009
Investigation into the dangers faced by lawyers who champion human rights and environmental justice. more...Activists fight to save 'people's law on the environment'
23rd September, 2009
Ruling would allow NGOs and individuals to challenge environmental damage in courts without prohibitive financial risks more...Cincinnati law to police polluting businesses
3rd July, 2009
Cincinnati has passed a new law introducing 'environmental justice permits', and will use police powers to force polluting businesses to clean up their acts or get out of town more...Life and debt
Molly Scott Cato
23rd April, 2009
This budget season, and so a short perambulation around the vexed question of the national debt seems in order. As a nation we've been living with debt for more the 300 years now, since 1694 to be precise, when Scottish privateer William Paterson persuaded the government of the time that creating £1.2 million of IOUs would get them out of their spending difficulties. more...The world's first environmental refugees
Dan McDougall
30th January, 2009
The disappearance of Lohachara beneath the waters of the Bay of Bengal created the world's first environmental refugees. Dan McDougall reports on other islanders in the Sundarbans delta who have no escape from the rising ocean. Photography by Robin Hammond more...'This is big'
Joss Garman
1st November, 2008
'Britain's astounding retreat from reason is now legitimising anarchy.' That was the conclusion of the hotblooded screaming radical Melanie Phillips, writing for The Spectator. more...In a climate of political chaos Zimbabwe's wildlife is being exterminated
Robin Hammond
1st June, 2008
more...Trade in precious minerals and timber continues to fuel violence and conflict across the globe
1st June, 2008
Revenues obtained from the often illegal extraction and supply of commodities such as timber and diamonds are directly bankrolling corrupt regimes and armed insurgency groups, and fund the purchase of weapons and other contraband goods that perpetuate cycles of conflict. more...The problem of greenwash - green-fiddling while Rome burns…
Pat Thomas
1st June, 2008
It's fair to say that we have our share of robust discussions in this office. Opinions get aired, fingers get pointed, occasionally voices get raised. It's all in a good cause. Setting the world to rights isn't always a civilised tea party. more...How modern economics causes both inner and outer climate change
Jonathan Rowe
1st April, 2008
It's the battle of the century. In one corner, the Economy – big, bloated, greedy and growing. In the other, the planet Earth – fragile, finite and fighting back. more...
Justice: 25/41 of 41
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The commons: an antidote to globalisation
Jonathon Rowe
1st April, 2008
The corporate market has become the institutional equivalent of a compulsive eater. It has a built-in hunger that cannot be filled, and it is hard to stop the damage within the framework of its own game. more...GM trees in US
Claire Robinson
1st November, 2007
The US government has given he go-ahead for a test plot of genetically modified (GM) eucalyptus trees in Alabama. For the first time, these trees will be allowed to flower and set seed, opening the door to potential widespread contamination of the American South. more...13 Globe-trotting indigenous grannies carry message of unity and prayer
Nicola Graydon
1st January, 2001
Grandmother Earth - Thirteen matriarchs from indigenous cultures are currently touring the world, promoting peace, unity and a respect for nature. nicola Graydon meets one of them, Mona Polacca more...A better kind of justice
Nandor Tanczos
13th June, 2000
Nandor Tanczos thinks the modern legal system could learn a lot from traditional ideas of justice, such as those of the Maori people more...ECOLOGIST COOKIES
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Story/Time: |
In this ceaselessly questioning book, acclaimed African American dancer, choreographer, and director Bill T. Jones reflects on his art and life as he describes the genesis of Story/Time, a recent dance work produced by his company and inspired by the modernist composer and performer John Cage. Presenting personally revealing stories, richly illustrated with striking color photographs of the work's original stage production, and featuring a beautiful, large-format design, the book is a work of art in itself. Like the dance work, Story/Time the book is filled with telling vignettes—about Jones's childhood as part of a large, poor, Southern family that migrated to upstate New York; about his struggles to find a place for himself in a white-dominated dance world; and about his encounters with notable artists and musicians. In particular, Jones examines his ambivalent attraction to avant-garde modernism, which he finds liberating but also limiting in its disregard for audience response. As he strives to make his work more personal and broadly engaging, especially to an elusive African American audience, Jones—who is still drawn to the avant-garde—wrestles with questions of how an artist can remain true to himself while still caring about the popular reception of his work. A provocative meditation on the demands and rewards of artistic creation, Story/Time is an inspiring and enlightening portrait of the life and work of one of the great artists of our time. Bill T. Jones is an acclaimed dancer, choreographer, and director. He is the artistic director, cofounder, and choreographer of the Bill T. Jones/Arnie Zane Dance Company and executive artistic director of New York Live Arts. He is the recipient of many awards and honors, including Tony Awards for FELA! and Spring Awakening, a Kennedy Center Honor, and a MacArthur Fellowship. In 2014, President Barack Obama awarded Jones the National Medal of Arts, the country's highest honor for achievement in the arts. "An experimental dancer/choreographer/performance artist improvises on the nature of story itself in a unique format. . . . A brave and often successful attempt to capture and display movement and intuition and the unspoken on the printed page."--Kirkus Reviews "Story/Time: The Life of an Idea is an ethereal memoir emblematic of this iconoclastic trailblazer's unpredictable approach to everything he does."--Kam Williams, AALBC.com "Readers interested in the intersection of dance, performance art, and the world of ideas will gain insight and inspiration from this thoughtful and singular work."--Carolyn M. Mulac, Library Journal "With the book, Jones attempts to explore the vital nature of his stage production back to its origins. . . . Anyone who has seen Jones' work has likely felt the need to press the 'pause' button; it carries a hypnotic current, a sense of relentless forward movement. This book, then, provides an ideal counterpoint. It suspends time, allowing Jones' story and space to unfold."--Jennifer Day, Chicago Tribune "As a written document, this book is clearly organized, quickly read, and dense with musings that can be dissected by dancers and non-dancers alike. As a piece of art, it is both process and product in one. The engagement and participation of audience member might be enhanced if the book is read and discussed in a group setting, which makes me curious to see how it will fit with the live performance and how many people will pair the two. The experiment in creation, design and performance certainly poses many questions that, identifying as a dance artist, I found myself musing in the context of own work. Likewise, as an academic, I found I was concurrently dissecting the book for use in a future class. I found the 'provocation' of personal context and its link to the audience's experience of art particularly poignant."--Katie C. Sopoci Drake, 4Dancers Acknowledgments vii Series: Subject Areas: | |||||||
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What is the historical significance of The Halliburton?
The Halliburton was built in 1809 as the home of Sir Brenton Halliburton, the first Chief Justice of the Nova Scotia Supreme Court. From 1885 to 1887, the building served as Dalhousie University's prestigious law school.
Where is The Halliburton located?
5184 Morris Street, on the corner of Barrington and Morris streets. This is in the south end of the downtown core. Approximately 35 min drive from Halifax International Airport.
What is included in your room rates?
Our nightly rates are in Canadian dollars, include breakfast and parking. Guests are welcome to enjoy our library (with complimentary Internet access) and garden courtyard free of charge.
Do you have parking?
As in most downtown areas, parking is a limited commodity. We have onsite parking for limited vehicles. Our main lot is accessible from Barrington Street. We have offsite parking (one block away) for remaining cars. Parking is vailable on a first come first served basis. Upon arrival, please park in our hotel loading area, directly in front of our hotel. We will direct you from there!
How do we get to The Halliburton from the Halifax International Airport?
If you require taxi or town car service, proceed to the arrivals area where you will find many options usually at a flat rate. Please inquire with the driver before you depart. Get driving instructions from the airport.
Do I need to rent a vehicle while in Halifax?
The Halliburton is within comfortable walking distance to many historic attractions and Halifax waterfront. There are numerous tour operators that provide city tours and transportation.
Can I bring my pets with me?
Unfortunately, we do not allow pets (big or small) to stay at our hotel.
Can I smoke at The Halliburton?
Our hotel, guestrooms, restaurant, courtyard, and all common areas are 100% smoke free.
Is your hotel accessible?
Due to the historic nature of our buildings, we do not consider ourselves accessible to those with physical impairments. All guest rooms require our guests to climb at least one flight of stairs.
Do you have elevators?


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Our story…here now at Amazon.ca!
Gary McHale book launch at: Freedom Press Canada — 2013 Freedom Symposium, November 9, 2013
Christie Blatchford: Caledonia law = Deep South law
"…the law in Haldimand County operates as the law in America's Deep South once worked, where there was one law for the white man, who could break it with impunity, and another for the black man. In Haldimand County, since the occupation began, there has been one law for natives and another for non-natives."
Helpless author Christie Blatchford, Globe & Mail, May 04/11
IN BOOKSTORES NOW: Caledonia's story, as told by Canada's award-winning author of 'Fifteen Days'…
"I'm sure a lot of people don't give a damn about what happened to the residents of Caledonia. I'm wondering where the next lawless takeover might take place — maybe in my area? Maybe in yours? People don't seem to care unless it affects them directly — that is, except for Gary McHale and Mark Vandermaas." Moose & Squirrel.ca
March 22/11: Free Thinking Film Society & International Free Press Society bring Caledonia to Ottawa
July 12, 2009 – THE END OF THE BEGINNING. After 4 arrests during a 31 month campaign the Canadian flag is legal once again in Caledonia
Tag Archives: Caledonia Class Action
Caledonia: what went wrong? Where do we go from here?
No one should assume that Caledonia is all wrapped up with a nice bow because the Caledonia Class Action suit has been settled. Even though the government was forced to write a cheque it can ill afford (politically and financially) … Continue reading


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Youth Basketball League to
Begin at Veterans Park Recreation Center
• Lee County Parks & Recreation: Veterans Park Recreation Center hosts Youth Basketball League
• What's happening: Registration is open and the deadline is fast approaching for the 2014 Spring Basketball League at Veterans Park Recreation Center. The league is open for children ages 8 – 15 and will run for ten weeks. Ages, skill level and number of players will determine how many teams there will be and what level they will play. Player skill evaluations are run for the purpose of distributing talent as evenly as possible throughout the league.
• Where: Veterans Park Recreation Center, 55 Homestead Road S., Lehigh Acres
• When: Registration deadline is Sunday. Practice starts Tuesday, Feb. 18, and games are played Wednesday evenings beginning March 5 – May 7.
• Cost: $35 per player-includes game shirt. Only checks accepted-payable to SYAL. Players registering must have a Lee County Parks & Recreation facility membership for a one time additional fee of $10.
• What to expect: Sheriff's Youth Activities League, SYAL, sponsors the basketball tournament once a year at Veterans Park. The basketball tournament is run by the Lee County Parks & Recreation staff and volunteers from the Lee County Sheriff's Office. Lee County Sheriff's Office Deputies assist with coaching and mentoring the athletes that participate in this event. The support from volunteers is paramount. If you are interested in coaching or mentoring kids, please contact Nancy Zukaitis at firstname.lastname@example.com or 369-1521. SYAL programs and activities are making a huge impact in the lives of the youth in Lee County.
• History: The Veterans Park Recreation Center was the first of its kind to open in Lee County for Parks & Recreation. It opened in December of 2004. Lee County Parks & Recreation joined together with Lee County School Board to build a Kindergarten-8th grade school with the recreation facility on the property.
• About us: Lee County Parks & Recreation has 228 positions, a $27 million budget and more than 31,500 acres of parks, preserves, facilities and other sites. The department oversees three recreation centers, 11 community centers, community parks, Conservation 20/20 lands, greenways, the Calusa Blueway Paddling Trail, four year-round pools, seven boat ramps, sports complexes including the Boston Red Sox and Minnesota Twins spring training facilities, dog-friendly facilities and pristine Gulf-of-Mexico beach parks.
Contact us at 533-7275 or firstname.lastname@example.com.
I need a basketball team for my son.
When do sign ups for the youth basketball league begin?
My son it's 8 years and half and he would like to play basketball please can you contac me thank you


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My Mark Twain
Howells, William Dean
It was in the little office of James T. Fields, over the bookstore of Ticknor & Fields, at 124 Tremont Street, Boston, that I first met my friend of now forty-four years, Samuel L. Clemens. Mr. Fields was then the editor of The Atlantic Monthly, and I was his proud and glad assistant, with a pretty free hand as to manuscripts, and an unmanacled command of the book-notices at the end of the magazine. I wrote nearly all of them myself, and in 1869 I had written rather a long notice of a book just winning its way to universal favor. In this review I had intimated my reservations concerning the 'Innocents Abroad', but I had the luck, if not the sense, to recognize that it was such fun as we had not had before. I forget just what I said in praise of it, and it does not matter; it is enough that I praised it enough to satisfy the author. He now signified as much, and he stamped his gratitude into my memory with a story wonderfully allegorizing the situation, which the mock modesty of print forbids my repeating here. Throughout my long acquaintance with him his graphic touch was always allowing itself a freedom which I cannot bring my fainter pencil to illustrate. He had the Southwestern, the Lincolnian, the Elizabethan breadth of parlance, which I suppose one ought not to call coarse without calling one's self prudish; and I was often hiding away in discreet holes and corners the letters in which he had loosed his bold fancy to stoop on rank suggestion; I could not bear to burn them, and I could not, after the first reading, quite bear to look at them. I shall best give my feeling on this point by saying that in it he was Shakespearian, or if his ghost will not suffer me the word, then he was Baconian.
At the time of our first meeting, which must have been well toward the winter, Clemens (as I must call him instead of Mark Twain, which seemed always somehow to mask him from my personal sense) was wearing a sealskin coat, with the fur out, in the satisfaction of a caprice, or the love of strong effect which he was apt to indulge through life. I do not know what droll comment was in Fields's mind with respect to this garment, but probably he felt that here was an original who was not to be brought to any Bostonian book in the judgment of his vivid qualities. With his crest of dense red hair, and the wide sweep of his flaming mustache, Clemens was not discordantly clothed in that sealskin coat, which afterward, in spite of his own warmth in it, sent the cold chills through me when I once accompanied it down Broadway, and shared the immense publicity it won him. He had always a relish for personal effect, which expressed itself in the white suit of complete serge which he wore in his last years, and in the Oxford gown which he put on for every possible occasion, and said he would like to wear all the time. That was not vanity in him, but a keen feeling for costume which the severity of our modern tailoring forbids men, though it flatters women to every excess in it; yet he also enjoyed the shock, the offence, the pang which it gave the sensibilities of others. Then there were times he played these pranks for pure fun, and for the pleasure of the witness. Once I remember seeing him come into his drawing-room at Hartford in a pair of white cowskin slippers, with the hair out, and do a crippled colored uncle to the joy of all beholders. Or, I must not say all, for I remember also the dismay of Mrs. Clemens, and her low, despairing cry of, "Oh, Youth!" That was her name for him among their friends, and it fitted him as no other would, though I fancied with her it was a shrinking from his baptismal Samuel, or the vernacular Sam of his earlier companionships. He was a youth to the end of his days, the heart of a boy with the head of a sage; the heart of a good boy, or a bad boy, but always a wilful boy, and wilfulest to show himself out at every, time for just the boy he was.
Terms Defined
Referenced Works


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No Bailout
NO BAILOUT....The bailout bill has failed. Two-thirds of the House GOP caucus primarily the lunatics in the Republican Study Committee, I assume voted against it. I have a feeling we might now get a bunch of emergency nationalizations whether we like it or not.
Our current financial crisis has never been explained well to the public because (a) it's mind-bogglingly complex and (b) even the experts don't entirely know what's going on. And the Paulson plan was never sold well because (a) the initial draft was indefensible and (b) the theory underlying it was uncertain and complicated. So Lou Dobbs and his brand of populist yahooism won out instead.
I don't know what happens next. Hopefully we'll get another bite at the apple, but with Congress adjourning and elections approaching, action is only going to get harder, not easier. In the meantime, I guess we just have to pray that all the Chicken Littles like me are worrying too much.
On another note, an upcoming debate whose main attraction is the possibility of Sarah Palin melting down amusingly is suddenly less appealing than it used to be. I'm not really in the mood for bread and circuses right now.


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Photo Proof that Nuclear War has begun in Yemen by Israel ~ link ~
Even the cheap video camera picked up the proton bombardment from a neutron bomb, as seen in the scintillation after the initial fireball. We expect Mossad and ADL trolls to be driven crazy by this one. No one watching this video can have a second's doubt that they are seeing an Israeli neutron bomb. Israel is the only nation that openly deploys neutron bombs, there is no one else.
Military war games increase globally - War Preparations In Progress ~ link ~
Joint and individual military exercise drills have proliferated across the globe over the past couple of months with no sign of these occurrences abating, if anything it appears as full steam ahead.
As these events are at an unprecedented level to-date, they point to potential war preparations, or if not, preparations for an event unbeknown to the general public at this stage.
How US healthcare is Dooming the American Economy ~ link ~
In a sign of the times, the IMF has essentially rebuffed U.S. claims of currency manipulation, to instead affirm that China's currency is "no longer undervalued" – essentially giving its approval for the inner circle what many have described as an incubating world currency.
Cloak-and-Dagger Case Studies: The FIFA Arrests of May 27, 2015 - Ahead Of Israel Expulsion Vote U.S. Orders Raid On FIFA
~ link ~ You need to read this one in full at the link! Stirling
Remember, the question is not the corruption of FIFA. In this world of ours, there is corruption everywhere, from Wall Street to the City of London, from Capitol Hill to New Delhi, from the Red Cross to the Red Sea, from Amnesty International to the Sierra Club. The question in such cases, rather, is: Why, in this upside-down world of ours, does the Invisible Government single out some individuals or groups, but not others?
Another interesting aspect of this is that our rulers no longer bother to hide their criminality. The press release of two prominent senators, followed one day later by criminal action against FIFA, is a mere warning to anyone, anywhere on earth, who would dare defy the bankers. As their current puppet-in-chief (Obama) bluntly put it:
"We have to twist arms when countries don't do what we need them to."
The FIFA-linked arrests on the eve of the re-election of the organization's chief are an obvious attempt to thwart Sepp Blatter's re-appointment, Vladimir Putin said, answering journalists' questions. He added it's another example of US meddling abroad.
Scientists at the University of Southampton predict that a cooling of the Atlantic Ocean could cool global temperatures a half a degree Celsius and may offer a "brief respite from the persistent rise of global temperatures," according to their study.


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this point, a full decade or so since the sub-genre re-ignited in a significant
way, we have seen virtually every kind of zombie movie possible. And on TV, The Walking Dead affords
us our weekly dose of zombie apocalypse action too.
one hand, it might be tempting to gaze at all these zombie productions and yell
"overkill," or some such thing.
see it differently, however.
surfeit of zombie films -- in conjunction with the rise of indie/DIY horror --
has permitted the genre to expand in new and unexpected directions.
there weren't approximately a hundred variations of the zombie film being made
each and every year, would we have the creative space for perfect little
cinematic grace notes like The Battery (2014), or this film, Maggie
suspect not.
now, the parameters of the zombie plague are so well-known -- don't get bitten,
shoot the zombies in the head, etc. -- that some movies have chosen to innovate
not by going big and epic, but by doing the opposite; by exploring the world of
the walking dead on a small and intimate basis.
by Henry Hobson, Maggie chooses this route.
film has received mixed reviews thus far, and I believe the negative reviews
have more to do with audience expectations than any particular quality of the
film itself.
people think of zombies and they want another World War Z (2013) or
some such effort: a gory war story told on a humongous scale.
is pretty
clearly not that thing.
the contrary, it's a sweet, unassuming film about a young girl who is going to
die from the zombie plague, Maggie (Abigail Breslin), and her heart-broken,
soul-broken father, Wade (Arnold Schwarzenegger).
true Hamlet-like
fashion, Wade is paralyzed about what to do for Maggie. He can't bear to kill her, or rob her of a
minute of her life.
nor can he allow her to continue suffering, or become a danger to others…including
his wife and other children.
off Maggie's
genre elements and what you get here is the simple story of a child with a
fatal disease, a child with no possible future.
Her father wants her to experience that future, but knows it is not to
if he can give her one more day, or a day and a half of that future…isn't that
a victory?
Maggie is nothing more and nothing less
than the above-description suggests. It's a gray, grim character piece that
happens to be highlighted by some surprisingly-effective acting from action
star, Schwarzenegger. He doesn't do his standard
action man shtick here: a wink and a gag, coupled with his unmatchable charisma
and screen presence.
we see the character's crushed heart, and total incapacity to resolve Maggie's
is often the case, it behooves you, going in to a film like Maggie
to know what sort of film you're watching.
This isn't a decapitation-a-minute gore fest. This isn't an action film at all. Maggie
is a sensitive and at times heart-wrenching drama about a family that
could be yours…or mine.
those grounds, Maggie is beautiful effort, an elegiac father-daughter love story.
shouldn't have brought me back."
modern America, a necro-ambulist plague infects much of the populace. Urban areas are hardest hit, but some rural
areas remain largely unscathed. The U.S. government has established a protocol
for dealing with those infected; those who have been bitten by the walking
dead. The suffering are allowed to go home with their loved ones for a time,
and then -- when "the turn" goes into full effect -- are shipped off to
quarantine camps, where they will die.
after she ran away, young Maggie Vogel (Breslin) is found by her farmer father,
Wade (Schwarzenegger) in a hospital ward for the infected. She's been bitten on the arm, and it's only a
matter of time before she will die.
kindly doctor informs Wade that first Maggie will lose her appetite, and then
she'll get it back…but for human flesh.
A sign of the "turn" is an increased ability to smell…meat. Worse, Maggie's disease is
progressing more rapidly than normal.
She has very little time left…
takes Maggie home to the family farm, where her step-mother, Caroline (Joely
Richardson) is understandably anxious about her presence. The Vogels' two younger children are sent
away with relatives during the duration of Maggie's care.
time, Wade is forced to confront his responsibility vis-à-vis his
daughter. A neighbor has kept her
daughter and husband -- both infected -- at home too, but they escape and
present a danger to the Vogels. Wade is
forced to kill them outright, rather than let them attack. He is warned by a local sheriff not to allow
the same thing in his house; not to keep Maggie at home so long that she is a
danger to others.
Maggie confronts the idea that she has no future. She goes out for an evening
with friends, including a boy who is bound for quarantine, and dreads the
possibility. Soon Caroline leaves the
house, and Maggie watches as Wade agonizes over his choices.
Maggie's "turn" begins. Her eyes go black, and she begins to sense those around
her not as people, but as food.
time for action is coming, but Wade can't bring himself to do what he must…
about what you did today. And what you may have to do tomorrow."
are very few fireworks in Maggie. The film is not about zombies overrunning our
infrastructure, or laying siege to our cities and communities. Instead, the film adopts a very simple
premise. Early on, a physician tells
Wade what to expect, and then we follow Maggie through the stages of the
plague. Remembering the doctor's words, we understand where Maggie "is" on the
plague continuum. There is no happy
ending and, indeed, no expectation of one.
of the best scenes in the film sees that physician talking frankly with Wade
about his options. This in-mourning dad
can take his daughter immediately to quarantine, a kind of hell-on-Earth
death-camp. He can give her a
government-made death cocktail to kill her, but she will suffer immensely because
the cocktail is painful.
Wade can end it quickly, with a bullet to the head, ending Maggie's suffering
once and for all.
one of those options is a good one, pretty plainly. And Wade spends the
majority of the film waiting, attempting to decide on his course of actions. He waits and he waits, and Maggie grows
waits because he can't bear for her to die.
waits because he can't before her to live in her condition.
the father, I sympathized completely with Wade's inaction. He knows he is going
to lose his beloved child, but he doesn't want to take one minute of life from
that child. He wants to wait till the
last possible moment, till the moment when her humanity is eclipsed, and he
knows she must die.
moment after moment, encounter after encounter, he finds that there is some of "Maggie"
still left in that "turning" zombie. Every time he sees that human quality, he --
again -- can't act. As viewers, we begin
to doubt, frankly, that he is capable of doing what everyone tells him he must
don't know, honestly, that I could do any better, in the same situation.
wife tells me she would choose option three for our son -- get it over with quickly
and painlessly -- and then turn the gun on herself rather than live with the
heart-break. Her reasoning is that it is wrong to let someone we love
suffer. I hear and understand that
rationale, and perhaps I'm a coward, or simply weak. But I don't think I could pull the trigger on
my son until I knew, 100% that there was no other option; that my child was
really and truly lost.
even then, I don't know if I could do it.
Maggie is the kind of film that makes you
consider such questions. What would you do if your child contracted a plague,
and was a danger to others?
a more mundane level, what would you do if your child contracted, simply, a
terminal illness?
would you talk to that child about the elephant in the room: the idea that he
or she simply has run out of future? The parent-child bond is one about
learning and preparing, conveying knowledge to the young. Suddenly, that contract is broken, because
the child will never grow up, never carry the responsibility to be an adult,
and go through life. What's left to talk about? To connect over?
see in one scene, as Wade focuses on the past, and the way he and Maggie's
mother met. Shared history is the only
thing left when the future is gone.
characters in the film, including Caroline, periodically warn Wade that Maggie isn't
herself anymore. And even Maggie coaches
her Dad on what he must do.
"You have to do it," she tells him.
still, Wade can't bring himself to act.
Perhaps there is a part of him that would rather die with Maggie than live
without her. Again -- and as I think my
wife was trying to express in her own way -- I sympathize with that instinct.
I appreciate how sensitively and intelligently (but not cloyingly…) the movie
explores its themes. In particular, it seemed to recognize a key fact about
human nature.
are always certain how strong you are...until it is your loved ones who are in
pain. And then certainty flies out the
window. Maggie captures that
notion splendidly.
Maggie presents a haunting scenario to
think about, and Arnold Schwarzenegger delivers a remarkable performance
here. He prowls the film with a hang-dog
expression, and an air of defeat. I
remember being none-too-impressed with his performance as a grieving husband
and Dad in End of Days (1999). I
didn't feel he had the depth, there, to nail that fallen character. But here, he absolutely nails the essence of
his character, Wade. He carries an
invisible weight on his shoulders, and there's a sweet gentleness to his
interactions with Maggie. Wade is never
disgusted, horrified or scared by her. But he is a wreck, facing what for him
is the end of his universe, the death of his child. I have never seen Schwarzenegger give such an
internal performance before, and his work here is accomplished and
Maggie's denouement, finds an intriguing answer
for Wade's existential dilemma. I don't
want to give it away, but it stems from Maggie's strength, and --as it should
-- from her love for her father. Maggie's
final act in this life is one that takes her father's experience fully into
account, and goes from there.
finally emerges then, is a portrait of a loving family facing a horrible
situation. The love that Wade and Maggie
share for one another is the thing that makes the pain so difficult to contend
with, but in the final analysis it is also the quality that gives both
individuals the strength to go on and do what they must.
terms of its imagery, Maggie exists in a kind of
de-saturated world of gray, where all joy and hope has been chemically
extracted from the visuals. In a world
without a future, how can the sky, the landscape, or the people be anything but
gray? The film's visuals are quite
lovely at times, though for some stretches it looks like the Vogel's live on
Matthew McConaughey's farm from Interstellar (2014)
Maggie is a sad -- nay grim -- film. Yet it is one I wholeheartedly recommend. You've
seen zombies of all types before – fast and slow, brain-eating or not -- but Maggie's
gift to us is worth noting. The film
takes the world of the zombie apocalypse and makes it feel personal and close
in a way that few genre films have managed.


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Wallys World
Photo by Jack Gould County CEO Janice Mittermeier isan unapologetic control freak, guarding the $3.8 billion-per-year government as if it were her household budget. I once requested a single controversial record from her staff and was handed more than a dozen boxes stuffed with unrelated documents. The document in question was, of course, missing. Even the elected supervisors—technically Mittermeier's bosses—have had the pleasure of requesting access to basic government information only to be told no. She would be the one, she said, who decided what supervisors need to know.
But Mittermeier is no longer in a league of her own. Here comes Walter Kreutzen, CEO of the county's embattled Transportation Corridor Agencies (TCA).
TCA runs the county's toll-road system, and Kreutzen, once the agency's chief financial officer, replaced William Woollett in the top job two years ago. Though less experienced than Mittermeier, Kreutzen is proving skillful in the art of bureaucracy.
In 1997, the man staffers call "Wally" tried quietly to force the TCA's board of directors to sign "confidentiality certificates." The certificates would have legally prohibited the public's watchdogs from ever divulging ugly truths about toll-road operations—particularly its finances—without staff approval. After the Weekly broke the story, Wally tried to argue that the unprecedented certificates were routine. Several alarmed board members said Wally didn't seem to understand that they —not he—were supposed to be running the agency.
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It was not the first time Wally had been confused. In 1995, as if they had already built a successful toll road, he and his mentor Woollett gave themselves exorbitant raises, bonuses and perks like free luxury cars and no-cost housing loans from TCA coffers. One major problem: the San Joaquin Hills toll road, their first of three roads, was at least two years behind schedule and wouldn't even be finished for another year. After it opened in November 1996, the agency was forced to admit, at least behind-the-scenes, that it had terribly mismanaged its finances, would have to drastically revise all its revenue projections and—to save itself from potential bankruptcy—refinance more than $1.7 billion.
That didn't stop Wally from proposing another round of lucrative pay raises for TCA brass last year, going so far as to spend $24,000 on a "study" to justify the move. This time, the board wisely said no.
Wisely because last month it became obvious to everyone that the San Joaquin Hills Transportation Corridor will never come close to achieving its original revenue projections. It can't even meet its more recent, heavily doctored projections. In February—after years of blatantly misleading public relations—a stubborn TCA finally admitted as much publicly. Not that it did so voluntarily: major Wall Street investment firms forced the agency's hand by downgrading TCA bond ratings and describing the toll road's financial health as "negative." To calm anxiety, the agency —until recently touted as an international model of private road construction—immediately dipped into $40 million in savings and promised to pinch pennies on administration. They also discussed raising tolls, an idea that has already proved to reduce traffic on the roads.
In a follow-up February meeting, concerned board members, including Collene Campbell and Todd Spitzer, the chairman, said it was time for the agency to stop winging it with numbers. The two admitted that they did not have answers to some of the most basic questions concerning toll-road operations.
"I have big concerns," Spitzer said. "We need to have a confidence level that we just don't have now."
High-priced consulting firm Wilbur Smith Associates—a master at painting rosy scenarios—had trouble explaining to Spitzer why it ignored obviously critical factors in calculating what turned out to be hilariously inaccurate road usage projections for the taxpayer-subsidized San Joaquin Hills toll road. After a round of heated questioning by Spitzer, a Wilbur Smith consultant could only say, "We really believed we were introducing an appropriate level of conservatism [into revenue projections]. Obviously, we were wrong. . . . We've learned a lot."
It was also revealed that the agency doesn't even know the first thing about ridership habits. Remarkably, a staffer reported that the agency "is flying more blind than we'd like to."
Frustrated, Spitzer noted that it was "the first time we've had this type of comprehensive session"; the TCA is 14 years old. He ordered that the staff arrange a future weekend workshop to clear up disturbing unanswered questions. A visibly annoyed Campbell said she was "devastated and publicly embarrassed" by the TCA's "mess" of an operation and that she expected forthright honesty and competence from the staff and consultants in the future.
Don't count on it, Collene. The Weekly requested access to official tapes of the two February meetings—likely the most critical and revealing in the TCA's shady history. "You're not going to believe this, but the staff says the tape machine wasn't working," one board member told us. "I know it doesn't look good, but that's what they say." Another board member said he was "shocked" to learn that no tapes had been made. "I can't explain it," he said.
On March 9, the agency's board met again. Apparently hoping to dodge another humiliating session, Wally made sure this meeting was almost devoid of substance. At one carefully staged point, three McDonald's restaurant representatives—who have a joint marketing agreement with the TCA—spoke glowingly about how proud they were to be working with the "fine" agency. The kind words seemed to delight board members, who smiled, made jokes and laughed during the brief 30-minute meeting. A McDonald's rep remarked, "Everyone here is so upbeat!"
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Awami Colony
From Wikipedia, the free encyclopedia
Awami Colony (Urdu: عوامی کالونی ) is one of the neighbourhoods of Landhi Town in Karachi, Sindh, Pakistan.[1]
There are several ethnic groups including Muhajirs, Sindhis, Kashmiris, Seraikis, Pakhtuns, Balochis, Memons, Bohras Ismailis, etc. Over 99% of the population is Muslim. The population of Landhi Town is estimated to be nearly one million.
External links[edit]
Coordinates: 24°51′N 67°09′E / 24.850°N 67.150°E
This Karachi-related article is a stub. You can help Wikipedia by expanding it. |


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I know that many of you don't spend a lot of time on Wrangler because it is our beginner trail. That side of the mountain has some cool views. Take a tour over there when you get a chance. You won't be disappointed.
Thursday, September 27, 2012
Wednesday, September 26, 2012
White and Yellow
More snow last night. The aspens look good. A little more snow tonight and then a beautiful, sunny weekend.
Tuesday, September 25, 2012
Couple More Hours of Winter
Today we had another couple hours of winter weather. I had my first winter driving on Loveland Pass this afternoon. It was snowing heavily and the roads were wet with just a teeny bit of slush. A-Basin's Lift Operations Supervisor, David Lee Roth, was at the top of Zuma Lift during the storm and took these photos. Right now the sun is out and the snowline is just above the base area.
Monday, September 24, 2012
Another Dusting
We have had another nice dusting of snow this morning. The next few days look kind of wet and cool although not cold enough for snowmaking. I am fully expecting an inch or two in the base area tomorrow. Each of these fall storms gets us a few steps closer to .........................
Sunday, September 23, 2012
Pika Place - New Conveyor Lift
We actually do have a pretty cool project going on in the base area. We are installing another conveyor lift, Pika Place. It will be Southeast of the bottom of Black Mountain Express. The lift will be fairly short with a very, very gentle slope. The site, within our teaching area, is specifically designed for teaching very small children. Over the last decade, you probably noticed the increase in youngsters skiing and riding at The Basin. Many people have discovered just how "kid friendly" A-Basin really is. For the little guys, this lift should speed the teaching progression and increase the fun factor.
The conveyor itself has already been delivery by Magic Carpet Ski Lifts. We are expecting delivery of pre-cast concrete foundations in the next week or so. Installation will likely occur during the first half of October.
The conveyor itself has already been delivery by Magic Carpet Ski Lifts. We are expecting delivery of pre-cast concrete foundations in the next week or so. Installation will likely occur during the first half of October.
Thursday, September 20, 2012
New Sewer Line
I wish I could tell you we have this amazingly cool new project going on at the ski area. The reality is that we are replacing a fairly big chunk of sewer line. Not the sexiest or funnest job you could imagine. There are times up here we get to ski the best snow, hike the best trail, attend the funnest dinner, etc. etc. etc. and there are times we have to put in a new sewer line. I guess you take the good with the bad. At least it is really expensive. Despite that, another beautiful fall day here. I savor days like this. Take care.
Tuesday, September 18, 2012
Beautiful Morning
Beautiful, crisp morning today. The forecast for the next week looks like spectacular fall weather. Most of yesterday's snow is gone. This week we should be seeing highs in the 50's and lows just touching freezing. While not quite cool enough for snowmaking, it is an extraordinary time to be in the mountains. I am not sure if it is just me, but the aspens this fall are especially bright and yellow.
Monday, September 17, 2012
Tuesday, September 11, 2012
Clam Bake
The Clam Bake was another hit. About 100 people joined up for a perfect Colorado "FALL" day. The leaves are starting to turn yellow around here. The Luv Brothers played some great music. The fiddle player was particularly good. Tony C and Becs were snipping Clam Bags and Chefs Pauli and Matt were serving up lobster and mussels. I snuck about 3 bowls of clam chowder.
Saturday, September 8, 2012
Monday, September 3, 2012
Lower Argentine North Fork Trail Closure
We are getting rolling on a pretty significant sewer line replacement project on High Noon. Sexy project eh? Unfortunately, the lower portion of the Argentine North Fork Trail will be closed starting Tuesday, September 4. Please avoid High Noon and the lower hiking/biking trail. You can still head up the summer road from the CDOT gate and catch the trail near the top of the North Fork ski trail. Sorry for the inconvenience.
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