text:
|Publication number
|Publication type
|Application number
|Publication date
|Mar 3, 1998
|Filing date
|Dec 28, 1995
|Priority date
|Dec 28, 1995
|Fee status
|Also published as
|Publication number
|Clyde L. Schultz, Ivan M. Nunez, David L. Silor, Michele L. Neil
|Original Assignee
|Johnson & Johnson Vision Products, Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (8), Referenced by (26), Classifications (18), Legal Events (3)
|External Links: USPTO, USPTO Assignment, Espacenet
This invention relates to polymeric compositions employed to make contact lenses, the composition containing a polymeric hydrogel material and desferrioxamine as a leachable material absorbed in the polymeric material.
It is known to employ hydrogel contact lenses to dispense therapeutic agents to the eye as disclosed in U.S. Pat. Nos. 3,787,378; 4,668,506; 4,713,244; 4,484,9:22; 4,931,279; and 5,213,801. It is not known, however, to employ desferrioxamine in contact lenses as the medicinal agent to kill or inhibit the growth of bacteria. Desferrioxamine has been employed as an anti-malarial agent for humans, but not as an agent delivered from a contact lens into the lachrymal fluids of the eye.
It is an object of this invention to provide a contact lens containing absorbed desferrioxamine that is leachable into the liquid surrounding the eye. It is another object to provide a contact lens that is capable of leaching sufficient desferrioxamine into the ocular liquid to substantially inhibit the growth of the bacteria present. Still other objects will become apparent from the more detailed description which follows.
This invention relates to a polymeric composition comprising a polymeric hydrogel material containing desferrioxamine (also referred herein as DFO) as an additive absorbed in the polymeric composition and leachable therefrom. The polymeric composition is especially useful as the material of a contact lens. A particularly advantageous embodiment of the invention is a contact lens of polymeric hydrogel material having desferrioxamine absorbed therein in an amount up to 400 mg/lens. The lenses which function best in this area are those that are hydrogels containing 35-60% water. At an ocular pH of about 7.0.-7.4 about 40% of the absorbed desferrioxamine can be leached into the lachrymal fluid to inhibit the growth of bacteria in the fluid.
This invention further relates to a contact lens for the eyes which is a shaped polymeric composition containing an anionic acrylic polymeric material having absorbed therein desferrioxamine, wherein the absorbed desferrioxamine is leachable into ocular fluid of an eye at the existing conditions of the eye and a contact lens for the eyes which is a shaped polymeric composition containing an anionic acrylic polymeric material absorbed into which is desferrioxamine that is leachable into ocular fluid at ambient conditions.
This invention further relates to a process for preparing a contact lens for use which comprises washing the lens in a saline solution; placing the washed lens in an aqueous solution of desferrioxamine in a concentration of 250 mg desferrioxamine/mL of solution at a pH of 7.0-7.4 for 60-80 hours; and removing the lens from the solution ready for use in an eye.
FIGS. 1 and 2 show the bacteriostatic effect of desferrioxamine.
FIGS. 3 and 4 show the release of desferrioxamine from a contact lens.
FIGS. 5, 6 and 7 show the desferrioxamine efficacy on animal eyes.
FIG. 8 shows the release of desferrioxamine from a contact lens.
FIG. 9, 10, 11 and 12 show the effectiveness of desferrioxamine released from a contact lens to inhibit the growth of bacteria.
FIG. 13 shows the release of desferrioxamine for different contact lens compositions.
Desferrioxamine (DFO) has not been studied as a bacterial growth inhibitor, although it has been used as an antimalarial agent on humans, on rats to initiate immunosuppression (U.S. Pat. Nos. 5,158,979 and 5,302,598) and generally as an iron chelating agent (U.S. Pat. Nos. 4,839,175 and 4,863,964). A study of DFO led to a series of experiments designed to test the possibility of its absorbance in a contact lens and subsequent release to the eye to prevent bacterial growth.
At the beginning of this study experiments were run to determine the utility of DFO in inhibiting the growth of bacteria found in the eye.
DFO was tested for its ability to control the growth of organisms in solution. The growth medium was an aqueous solution containing 0.9% saline and 0.1% peptone at a pH of 7.1.
This growth medium was used as the control in the desferrioxamine solution assays. The experimental test solution consisted of the above growth medium plus 100 mg/mL of desferrioxamine with an adjusted pH of 7.1. Both control and experimental test solutions were filter sterilized through a 0.2 microns filter. The indicator organisms, Staphylococcus aureus (ATCC 6538) and Pseudomonas aeruginosa (ATCC (15442) were passaged overnight in the control growth medium at 35 degrees C. The following day, 0.5 mL of the respective indicator organism was added to 50 mL of the control and experimental test solution. Both solutions were then incubated at 35 degrees C with gentle agitation. Samples were collected at time points of 0, 3, 5, 8, and 24 hours. After making dilutions of the samples, TSA (Tryptic soy agar) pour plates were prepared and incubated at 35 degrees C overnight. Colony counts were performed the following day. The results demonstrating the bacteriostatic effect of desferrioxamine are shown in FIGS. 1 and 2. The results show a reduction of bacterial counts exposed to desferrioxamine as compared to bacteria not exposed to desferrioxamine beyond three hours of exposure. This was consistent for desferrioxamine in solution and released from a hydrogel lens. Statistically significant differences comparing desferrioxamine treated and untreated bacteria were observed for both species. CFU means colony forming units. The data showed that desferrioxamine released from a polymeric hydrogel lens materials are bacteriostatic to both Gram positive and Gram negative bacteria over time. This may reduce the numbers of bacteria sufficiently to abort a potential bacterial infection.
Contact lenses were prepared containing absorbed DFO, and those lenses were tested to see if the DFO might leach out of the lens and perform the bacterial growth inhibition as shown in Example 1. Polymeric hydrogel lenses containing approximately 60% water were soaked in a solution (0.9% saline) containing 100 mg/mL DFO for 72 hours and identified as experimental lenses. Control lenses were soaked for 72 hours in a solution (0.9% saline) containing no additive, and were identified as control lenses. The target organism used was Staphylococcus aureus (ATCC 6538). In this assay, one lens was added to 0.5 mL of the growth medium containing approximately 500 CFU/0.5 mL of the indicator organism. Three lenses (experimental and control) were set up for each time point. Samples were collected at time points of 0, 3, 5, 8 and 24 hours. After making dilutions of the samples, TSA pour plates were prepared and incubated at 35 degrees C overnight. Colony counts were determined the following day.
FIG. 3 shows the release of DFO from a contact lens is active over a period of time and performs a significant growth control over bacteria.
In FIG. 4 it can be seen that this system shows a consistent release of DFO over a long period of time; in that the system was still active after 50 hours of use. The released DFO is biologically active.
There have been no studies in the past of DFO being used in the eyes for control of bacterial growth. It has been known that if Pseudomonas aeruginosa is placed in the abraded eyes of rabbits an infectious bacterial keratitis will develop. It was decided to see if bacterial growth in the ocular environment could be controlled by the use of bactericides that might leach out of contact lenses. A series of experiments were run on cats and involving the following steps. Each cat would have one eye covered with an experimental lens and the other eye with a control lens, the former containing absorbed DFO and the latter containing no additive.
1. Experimental contact lenses were prepared by placing washed polymeric hydrogel lenses in 250 mg/mL desferrioxamine solution (pH 7.2) for 72 hours prior to use.
2. Immediately prior to use, all lenses were washed with saline.
3. Diluted Pseudomonas aeruginosa (15442) was added to the control eye of the cat (50 microliter).
4. The control lens was placed onto the control eye of the cat which had been gas anesthetized.
5. Another 50 microliter of bacteria was added to the control eye of a cat following the addition of the lens.
6. The control eye was taped closed.
7. Steps 2-6 were repeated on the experimental eye to which the experimental lens was placed.
8. The experiment was allowed to progress for four hours.
9. After this four hour period, the contact lenses were removed and the animals were allowed to wake-up and recover. The animals were examined for corneal edema, conjunctivitis and exudate production.
10. The lenses were removed, placed in saline solution and processed by sonication to recover bacteria.
11. The experiment was conducted with three different inoculum concentrations; 8�104, 1�107 and 1�108. There were four animals per group.
12. Animal eyes were examined histopathologically for evidence of pathology.
The results are shown in FIGS. 5-7.
The two lowest inoculum groups showed a decrease in bacterial counts of at least 60% in 6 of 8 animals when the bacterial counts of the control eye were compared to the experimental lens containing eye (FIGS. 5 and 6). One animal died due to a reaction to the gas anesthesia (133) and one animal showed an increased number of bacteria on the experimental lens (126). Necropsy revealed a systemic infection unrelated to the experimental model. The four animals in the highest inoculum group showed no change or increases in counts when the bacterial recovery was compared between control and experimental lenses (FIG. 7). This indicated that there were so many bacteria present that it was not possible to control their number. However, at the lower inoculum levels it was possible to control the bacterial population. The average number of bacteria recovered as a difference between control and experimental lenses in FIG. 5 was 2.6�104. The average number of bacteria recovered as a difference between control and experimental lenses in FIG. 6 was 1.4�103. Other authors have shown that active corneal infections may develop with an inoculum of 1.0�104 CFU of Pseudomonas aeruginosa. Animals may be symptomatic with as few as 1.0�103 CFU.
Histopathological examination of eye tissue did not reveal any overt pathological changes either in experimental or control animals.
The data indicated that DFO may be delivered from polymeric hydrogel materials in sufficient quantity to reduce bacterial populations during a closed eye period. However, it is possible to add bacterial inoculum in sufficient quantity to overwhelm the positive effects of DFO. This was seen in the highest inoculum group. The results of this experiment confirm the data obtained from in vitro experiments with DFO either delivered from a lens, or free in solution. It should also be noted that the number of bacteria used in this work was artificially high. In a real world situation the starting inoculum for an infection would probably be less than 1�103 CFU/lens.
Gross examination of the animals following lens removal did not detect any unusual morphological changes of the animal eyes. This appeared to be true regardless of the inoculum level. This indicates that neither the DFO or the high inoculum levels perturbed the ocular environment to any great degree up to four hours. Other authors have shown that gross infections will occur should the cornea or conjunctiva be compromised.
The available human clinical information suggests that worldwide most people who have adverse responses due to contact lens wear have non-infectious immunological reactions or acute immune syndrome or noninfectious peripheral ulcers. However, in certain countries the rates of infections due to bacterial contamination appear to be somewhat higher. In these countries a strategy for reducing live bacterial counts would be appropriate. This may be done by passive mechanisms, such as a non-biological adhesive lens, or actively by the addition of some anti-microbial agent.
It has been shown using an animal model that an anti-microbial agent may be delivered from a hydrogel contact lens material that is efficacious in reducing bacterial counts in vivo. The level of reduction is such that most infections may be aborted prior to the onset of frank disease. The data indicate that this agent appears to be safe to ocular tissue.
The same procedure as set forth in Example 3 was repeated and the lenses were tested against Pseudomonas aeruginosa. Similar results were obtained by comparing FIG. 8 with FIG. 4.
A series of experiments were run to study the effectiveness over different time periods of the system in releasing DFO to inhibit the growth of bacteria. In each instance the bacteria studied were Pseudomonas aeruginosa (15442). The control lens was treated with no DFO while the experimental lens was treated in a solution containing 200 mg DFO/mL. The results are shown in FIGS. 9-12 representing 0, 3, 6, and 9 hours respectively. The measurement shows the amount of colony forming units (CFU) remaining in the solution at the end of the treatment time. It will be seen that there is a large difference between the growth inhibition by the DFO-treated lens as compared to the control lens. The T-shaped object at the top of each bar shows the standard deviation from the observed value.
A similar series of tests were run to test the applicability of different types of contact lenses as the carrier for DFO. The procedure of Example 2 was repeated employing four different types of polymeric hydrogel lenses, differing particularly in water content or polymer type. In each instance a control with no DFO was compared to a lens containing leachable DFO prepared by soaking the lens in a solution of 50 mg DFO/mL for 72 hours. It will be seen in FIG. 13 that the lower water content polymeric materials (water content=35-55%) are effective in releasing DFO. One sample of high water content (70%) showed no effect at all, and was not included in the chart.
This invention is directed principally at the absorption and leaching of DFO as a bacterial growth inhibitor. The basic concept of employing a contact lens to dispense a medical component is known, but if one considers the practicality of the invention, the lens must be a polymeric hydrogel of low water content (35-60%), and the medical component must be capable of being absorbed into the lens in sufficient quantity to form a reserve that will leach out at a generally consistent rate over a period of time, e.g., up to 24 hours. Other types of materials that might be absorbed into a contact lens and leached out into the lachrymal fluids include antibiotics, tissue healing agents, and anti-inflammatory agents. Some of these will function properly and other will not because of their chemical and physical properties. Desferrioxamine, however, is a preferred additive in this invention.
The polymeric material of this invention is a polymeric hydrogel which has been described in the prior art (e.g., see U.S. Pat. No. 5,256,751) as a hydrophilic polymer capable of forming a hydrogel when contacted with water. Examples of monomers forming hydrophilic polymers are hydroxyesters of acrylic or methacrylic acid, methycrylic acid (MAA), hydroxyethyl methacrylamide (HMA), DMA, NVP, styrene sulfonic acid, and other liydrophilic monomers known in the art.
Examples of hydroxyesters of acrylic or methacrylic acid include HEMA, hydroxyethyl acrylate (HEA), glyceryl methacrylate, hydroxypropyl methacrylate, hydroxypropyl acrylate and hydroxytrimethylene acrylate. The preferred hydroxyester is HEMA.
The most preferred hydrophilic monomer is HMA.
The relative proportion of the monomeric components depends on numerous factors, for example, the specific monomeric components chosen, and the final properties of the polymer desired, and can be readily determined empirically. Generally, the weight ratio of the hydrophilic monomer to the acyclic monomer is between about 1.5:1 to about 9:1, preferably about 2:1 to about 4:1, more preferably about 2.5:1 to about 3.5:1. If the amount of the hydrophilic monomer were greater than about 90%, then the resultant polymer will not show good mechanical properties (strength). On the other hand, if the amount of the hydrophilic monomer were less than about 60%, then the water content and oxygen permeability of the resultant hydrogel polymer will not be sufficiently high.
Additionally, as described in U.S. Pat. No. 5,292,350, polyfunctional crosslinking monomers, such as ethylene glycol dimethacrylate (EGDMA) and trimethylolpropane trimethacrylate (TMPTMA), can be used as comonomers in relatively small amounts in the reaction mixture to improve the dimensional stability and other physical properties of the lens. Similarly, other components may be added for specific applications, for example, to impart UV absorbing properties to the lens. Other similar disclosures of polymeric hydrogels are found in U.S. Pat. Nos. 4,495,313; 5,311,223 and other patents.
For the purposes of the present invention it is important that the water content of the hydrogel is about 35-60% by weight. The polymer may be ionic or nonionic; anionic polymers are not operable. Preferred polymer compositions are terpolymers of hydroxymethylmethacrylate, ethylene glycol dimethacrylate, and acrylic or methacrylic acid.
While the invention has been described with respect to certain specific embodiments, it will be appreciated that many modifications and changes may be made by those skilled in the art without departing from the spirit of the invention. It is intended, therefore, by the appended claims to cover all such modifications and changes as fall within the true spirit and scope of the invention.
|Cited Patent
|Filing date
|Publication date
|Mar 19, 1982
|Jan 22, 1985
|Mia Lens Production A/S
|Preparation of hydrogel for soft contact lens with water displaceable boric acid ester
|Jul 28, 1986
|Jun 13, 1989
|Liposome Technology, Inc.
|Liposomes with enhanced retention on mucosal tissue
|Apr 19, 1989
|Oct 27, 1992
|New York University
|Method and compositions for treating pneumocystic carini infections
|Jun 15, 1992
|Aug 17, 1993
|Bausch & Lomb Incorporated
|Polymer compositions for contact lenses
|Feb 8, 1993
|Oct 26, 1993
|Vistakon, Inc.
|Ophthalmic lens polymer incorporating acyclic monomer
|Apr 24, 1992
|Mar 8, 1994
|Vistakon, Inc.
|Method for preparing tinted contact lens
|Jul 7, 1992
|Apr 12, 1994
|New York University
|Method and compositions for treating pneumocystic carinii infections
|Jun 7, 1993
|May 10, 1994
|Johnson & Johnson Vision Products, Inc.
|Ophthalmic lens polymer incorporating acyclic monomer
|Citing Patent
|Filing date
|Publication date
|Feb 19, 2000
|Jun 25, 2002
|Clyde Lewis Schultz
|Drug delivery system for antiglaucomatous medication
|Jan 10, 2003
|Jan 30, 2007
|Directcontact Llc
|Growth factor delivery systems for the healing of wounds and the prevention of inflammation and disease
|Apr 1, 2005
|Nov 17, 2009
|Directcontact Llc
|Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease
|Jun 5, 2003
|Dec 29, 2009
|University Of Florida Research Foundation, Incorporated
|Ophthalmic drug delivery system
|Sep 4, 2007
|Dec 6, 2011
|University Of Florida Research Foundation, Incorporated
|Dispersions of microemulsions in hydrogels for drug delivery
|Sep 4, 2007
|Dec 13, 2011
|University Of Florida Research Foundation, Incorporated
|Contact lens based bioactive agent delivery system
|Mar 17, 2004
|Sep 25, 2012
|University Of Florida Research Foundation, Incorporated
|Ophthalmic drug delivery system
|Sep 2, 2008
|Dec 22, 2015
|Directcontact Llc
|Device and method for the delivery of drugs for the treatment of posterior segment disease
|Jun 25, 2002
|Dec 26, 2002
|Schultz Clyde L.
|Drug delivery system for anti-glaucomatous medication
|Jan 10, 2003
|Oct 30, 2003
|Schultz Clyde L.
|Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease
|Apr 25, 2002
|Oct 30, 2003
|Schultz Clyde L.
|Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease
|Jun 5, 2003
|May 20, 2004
|Anuj Chauhan
|Ophthalmic drug delivery system
|Mar 17, 2004
|Dec 2, 2004
|Anuj Chauhan
|Ophthalmic drug delivery system
|Oct 22, 2004
|Apr 7, 2005
|Schultz Clyde L.
|Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
|Oct 22, 2004
|Apr 21, 2005
|Schultz Clyde L.
|Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease
|Apr 1, 2005
|Sep 8, 2005
|Schultz Clyde L.
|Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease
|Apr 9, 2004
|Sep 22, 2005
|Schultz Clyde L
|Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
|Apr 9, 2005
|Nov 17, 2005
|Directcontact Llc
|Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases
|Sep 4, 2007
|Mar 27, 2008
|Anuj Chauhan
|Dispersions of microemulsions in hydrogels for drug delivery
|Sep 2, 2008
|Dec 25, 2008
|Directcontact Llc
|Device and Method for the Delivery of Drugs for the Treatment of Posterior Segment Disease
|Sep 4, 2007
|Mar 5, 2009
|Anuj Chauhan
|Contact lens based bioactive agent delivery system
|Oct 23, 2008
|Apr 29, 2010
|Shane Mao
|Contact lens cases for delivery of ophthalmic agents
|May 30, 2008
|Jul 15, 2010
|Anuj Chauhan
|Extended release of bioactive molecules from silicone hydrogels
|Aug 6, 2014
|Nov 26, 2014
|Eye patch containing nanosphere and microsphere
|Apr 9, 2005
|Nov 24, 2005
|Directcontact Llc
|Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases
|Apr 9, 2005
|Nov 23, 2006
|Directcontact Llc
|Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases
|U.S. Classification
|424/400, 424/487, 424/427, 424/422, 424/429
|International Classification
|Cooperative Classification
|European Classification
|Aug 10, 2001
|Fee payment
Year of fee payment: 4
|Aug 25, 2005
|Fee payment
Year of fee payment: 8
|Aug 5, 2009
|Fee payment
Year of fee payment: 12


text:
Gonzales is Out
Attorney General Alberto Gonzales, getting almost as much heat as Iraqi Prime Minister Nouri al-Maliki, has resigned, according to news reports.
It was just a matter of time, after his own party savaged him earlier this month. Now you can relax and enjoy some of his greatest hits, starting with his confirmation hearing in January 2005.
His reign was pure torture, even after John Ashcroft's gospel show.
Even when he was Bush's counsel during the POTUS's term in Texas as the nation's hangingest governor, Gonzales was lame. As I noted in January 2006, "his timing is off, but his boss's execution never is."
Gonzales was small, but he was slow
Get the ICYMI: Today's Top Stories Newsletter Our daily newsletter delivers quick clicks to keep you in the know
Catch up on the day's news and stay informed with our daily digest of the most popular news, music, food and arts stories in New York, delivered to your inbox.
Upcoming Events
UniverSoul Circus
TicketsSun., May. 28, 12:30pm
New York Yankees vs. Oakland Athletics
TicketsSun., May. 28, 1:05pm
Pinstripe Pass: New York Yankees V Oakland Athletics
TicketsSun., May. 28, 1:05pm
New York Red Bulls II vs. Charleston Battery
TicketsSun., May. 28, 2:00pm
Sponsor Content

subset: commoncrawl


text:
Hosting Hell: 10 Things That Will Go Wrong - And How to Prevent Them »
If you want to avoid entering the hosting hell dimension, here are 10 potential entertaining glitches, and how to avoid them.
YP - The Real Yellow PagesSM - helps you find the right local businesses to meet your specific needs. Search results are sorted by a combination of factors to give you a set of choices in response to your search criteria. These factors are similar to those you might use to determine which business to select from a local Yellow Pages directory, including proximity to where you are searching, expertise in the specific services or products you need, and comprehensive business information to help evaluate a business's suitability for you. "Preferred" listings, or those with featured website buttons, indicate YP advertisers who directly provide information about their businesses to help consumers make more informed buying decisions. YP advertisers receive higher placement in the default ordering of search results and may appear in sponsored listings on the top, side, or bottom of the search results page.
1320 S Hurstbourne PkwyLouisville, KY 40222
9730 Von Allmen CtLouisville, KY 40241
Typical Olive Garden food, but great service. One of my favorites!
12336 Shelbyville RdLouisville, KY 40243
2535 Hurstbourne Gem LnLouisville, KY 40220
Best steak place in Louisville.
10801 Locust RdLouisville, KY 40299
The pieces of fish are huge and very inexpensive. I highly recommend.
657 S Hurstbourne PkwyLouisville, KY 40222
We love this place!!! The bang bang shrimp is the best thing i've ever eaten & we've always had excellent service.
12339 Shelbyville RdLouisville, KY 40243
Grew up going here, and keep going back. Great food and awesome service.
11320 Maple Brook DrLouisville, KY 40241
This restaraunt has fantastic food and great service.
10609 La Grange RdLouisville, KY 40223
9307 New La Grange RdLouisville, KY 40242
Though it doesn't look it, being a small restaurant sitting in a corner of a quaint little shopping center, Corner Cafe will deliver a blow of taste…
615 S Hurstbourne PkwyLouisville, KY 40222
From Business: Mimi's is a beloved neighborhood cafe known for indulgent breakfast and brunch with signature "Mimi-mosas" and seasonal muffins, French-American "Le Duet" lunch c…
12480 La Grange RdLouisville, KY 40245
4021 Summit Plaza DrLouisville, KY 40241
Love the lasagna at Martini and you have to get their house dressing on salad because it is the best!!
2809 N Hurstbourne PkwyLouisville, KY 40223
205 N Hurstbourne PkwyLouisville, KY 40222
1850 S Hurstbourne PkwyLouisville, KY 40220
12410 Shelbyville RdLouisville, KY 40243
Got to try the authentic Chinese menu! Wonderful food, friendly service. I've been several times and brought friends. Will keep coming back for s…
4110 Hampton Lake WayLouisville, KY 40241
1325 S Hurstbourne PkwyLouisville, KY 40222
14049 Shelbyville RdLouisville, KY 40245
We enjoyed an excellent hickory smoked burger and fried chicken with green beans. All was cooked just right with great flavor.
101 Whittington PkwyLouisville, KY 40222
I ate here for the first time last night and I was blown away. I have lived in different cities in the Midwest, and I have NEVER found a restaurant…
2923 Goose Creek RdLouisville, KY 40241
Goose Creek Diner is fantastic! We feed 40 people at a time here at Neil Huffman Nissan and Chris and his crew never disappoint. Today we had meatlo…
153 S English Station RdLouisville, KY 40245
3601 Springhurst BlvdLouisville, KY 40241
I paid a visit to this establishment during lunch and I was not impressed. My chicken salad just tasted like bagged salad mix with cold chicken tend…
617 S Hurstbourne PkwyLouisville, KY 40222
Great food at a decent price!
9464 Brownsboro RdLouisville, KY 40241
Best fast chinese around! YUM!
9409 Shelbyville RdLouisville, KY 40222
1903 Embassy Square BlvdLouisville, KY 40299
From Business: Charr'd is a culinary experience designed to give it's guest a true taste of Kentucky while highlighting one of its greatest creations Bourbon!
11519 Shelbyville RdLouisville, KY 40243
401 S Hurstbourne PkwyLouisville, KY 40222
I love This place. I have been there with 3 different groups of people to celebrate birthdays and everyone was pleased with the food and the service…
If you want to avoid entering the hosting hell dimension, here are 10 potential entertaining glitches, and how to avoid them.
If you're a guest at the season's events, make sure that you're part of the celebration, not part of the problem
We want your holiday parties to be the talk of the season, so we've rounded up our top tips on how to pull off hosting without a h…


text:
Posted by ESPN.com's Brian Bennett
Preseason camp begins in just a few weeks, and freshmen are already reporting to campus all over the country. Which new players could make an immediate impact at Notre Dame? Here are a look at three incoming freshmen to keep an eye on when practice begins:
• Manti Te'o, LB: Pick an accolade, any accolade. Te'o was USA Today's defensive player of the year, The Sporting News 2008 high school athlete of the year, the inaugural winner of the high school Butkus Award and the No. 2 overall player on the ESPNU150. Simply put, the 6-foot-2, 225-pounder from Hawaii is a can't-miss prospect and the crown jewel of this recruiting class. He could be the kind of dominating, athletic linebacker that the Irish have lacked. And given Notre Dame's defensive lapses, it wouldn't be a surprise at all if he works his way into a starting role immediately.
• Cierre Wood, RB: One of the top prep running backs in the nation last year, Wood rushed for 1,632 yards and 20 touchdowns as a senior following a 2,600-yard junior campaign. He has good size at 6-feet, 192 pounds, and scouts love his vision and balance. Notre Dame's problems in the running game have been well documented. If Armando Allen, James Aldridge or others don't step forward, perhaps Wood will get a shot.
• Shaquelle Evans, WR: Ranked by ESPN's Scouts Inc. as the nation's fourth-best wide receiver last year, the California native chose the Irish over USC. He caught 51 passes for 810 yards and 11 touchdowns as a senior and has speed (6-1, 203 pounds), size and explosiveness. Because receivers have a relatively easier adjustment to make to the college game than other positions, Evans has a better chance to get on the field quickly than some of the other highly-touted Irish recruits, like offensive linemen Chris Watt and Zach Martin and defensive tackle Tyler Stockton. But Evans will have to crack what looks like Notre Dame's most loaded position group, which already boasts stars Golden Tate and Michael Floyd.


text:
Only images and pdf files may be uploaded as attachments.
Thank you, your message has been sent. You will be contacted by email when the artist responds. You can also keep track of your messages in your personal inbox.
Kathryn Edwards is considering offers on this artwork. Please submit your offer below and they'll get back to you shortly. Note, offers are always made in the artist's chosen currency
Send Offer
Thank you, your offer has been sent. You will be contacted by email when the artist responds. You can also keep track of your offers in your account.
A local beauty spot on the top of the Tredegar mountain in the South Wales Valleys where sheep and horses roam unfettered and families of ducks cross the mountain road in an orderly line much to the amusement of the occasional, patient, passing motorist.
acrylic paint
Acrylic painting by Kathryn Edwards
United States
This artwork is shipped to you by Kathryn Edwards, and will be packaged in a reinforced envelope. Artworks are dispatched within 5 working days from United Kingdom.
Change your country
United Kingdom
Acrylic painting
Forgot password?
Callingall artlovers
Welcome to Artfinder,the art marketplace
Join today to challenge your sensibilities, be moved to tears, find the next big star of the art world, or just to make your house your home.
10,000+ global artists. 250,000+ original artworks
We promise to never pass on your email -
see our privacy policy and
Terms of use


text:
At the beginning of 1994, when so many raw materials were seen as ridiculously cheap after a long period of sluggish global consumption growth and over-production, the potential for profits from a stake in commodities was reckoned to be huge.
Not only were other economies forecast to follow the US recovery, which would be good for demand, but production was also turning down after being reined in following years of barely profitable prices, or hit by bad weather.
At the same time, other investments, such as stocks and bonds, were losing their attraction and interest rates were falling.
After years of neglect, commodities are enjoying a revival. 'This is one of the most bullish periods we have seen for some considerable time, even better than the late Eighties,' says Lawrence Eagles, commodities analyst at futures brokers GNI. 'The outlook for pretty much the whole complex is bullish.'
It is a view shared by Alec Gordon, senior commodities analyst at the Economist Intelligence Unit, a private business consultancy. 'Broadly speaking', he says, 'the cyclical downturn is over, although there are exceptions'- as crude oil's and wheat's recent poor performances show.
Opec's failure to cut production last week sent Brent blend tumbling to just a whisker away from February's five-year low of dollars 12.90 a barrel.
In many markets, the growing involvement of speculators and investors is making for increasingly volatile trading. A herd instinct can quickly develop as they follow the trend, often making investment decisions on computer-based trading systems that have little to do with the fundamental supply-and-demand picture.
This can take a market dramatically up, and just as sharply down, all in a matters of days. The recent gyrations of some metals reveal just this.
But it is not only 'outsiders' that have been buying. Traders and manufacturers are also more active today, seeing sense in stocking up a little after years of hand-to-mouth market operations.
For them, fundamentals are what count and almost everywhere they look they see that stocks available to the market are falling.
Yet for many commodities - especially base metals, coffee, cocoa, rubber, wool, sugar and cotton - the drop is from very high levels. And existing inventories still provide a nice cushion against the developing production shortfalls. There is also a risk that further price gains may reverse the trend to lower output, while structural changes - such as the planting of high-yielding hybrids and new technologies that have cut the use of metals in many applications - are also a check on upward price momentum.
Patchy demand growth and prevailing high stocks explain why many analysts do not foresee the potential in 1994 for an across-the- board boom in commodities on a par with the surges of the early 1970s and early 1950s. Prices of base metals may be up by about 20 per cent on average, but from a very deep trough. Last autumn, copper, aluminium, nickel, tin and zinc were at their cheapest for some decades, and all are still well down on past peaks. The outlook is also less than brilliant.
'The disproportionate demand- side boost evident during the early stages of an economic recovery has already occurred in the US. And while demand will continue to grow, the rates experienced in 1992 and 1993 are simply unsustainable,' says Angus MacMillan, analyst at Billiton-Enthoven Metals.
Meanwhile, Japan, Germany and most of the rest of Western Europe have yet to show an improvement in industrial output - the main driving force behind metal consumption.
The key to base metals, many argue, is held by the producers. But will the production cutbacks on the scale already planned really materialise for aluminium and will zinc smelters likewise introduce the restraint that the experts say is needed?
On the demand side, textile activity is picking up from last year's very low operating rates. Meanwhile, the US motor industry has been stepping up purchases of rubber - 70 per cent of world output in rubber is now used to make tyres. Yet much more influential in recent price gains - which have seen rubber at a five-year peak and wool and cotton at their best levels for several years - has been the prospect of market deficits this year because of production setbacks.
Conversely, a downturn in output after many years of over-production is behind the highest wholesale coffee, cocoa and sugar prices for about four years. Sporadic buying by investment funds has helped give these markets a leg-up, with coffee separately boosted by the producing countries' successful export retention scheme.
Rising raw material costs are inevitably stoking fears of inflation, which have encouraged some buying of gold - the traditional hedge. But falling oil prices have taken the edge off gold's rise, with the metal yet to break above last August's three-year high of dollars 407 an ounce.
In contrast, other precious metals are doing noticeably better, with platinum up on worries about South African supply lines and silver jumping a week ago to a five- year high of dollars 5.75 an ounce. It is traditionally the investors' favourite, because its low unit cost - one-sixtieth of gold's - makes it a relatively cheap way into commodities.
'In the US if you think commodities and inflation are going to take off, you buy silver,' says one dealer. Investment funds have been doing just that, encouraged by the fact that the use of silver - which, like platinum, is much more an industrial metal than gold - has begun to exceed newly mined supplies.
But silver stocks are huge and some of the more extravagant price forecasts for it are beginning to look a little dubious - something that may be true for commodities generally.
(Photograph omitted)
- More about:
- Gold
- Investment
- Manufacturing
- Metals


text:
Pop-up blocker | How to | Firefox Help
3.2 Is the pop-up blocker on and enabled for this site? . Pop-up blocking is turned on by default, so you don't have to worry about enabling it to prevent pop- ups .
Adblock Plus :: Add-ons for Firefox
To try the thousands of add-ons available here, download Mozilla Firefox, a fast, . pop-up blocking support for the cases where the built-in pop-up blocker fails. .
PopupMaster :: Add-ons for Firefox
To try the thousands of add-ons available here, download Mozilla Firefox, a fast, . Places the popup blocker icon in the status bar, regardless of site settings. .
Popup Blockers - How to Disable the Popup Blocker in Firefox
Use these steps to permanently or temporarily disable the Mozilla Firefox popup blocker for a particular website. Difficulty: Easy. Time Required: 1 minute .
adware removal for windows xp
FAQ - Disable Pop-Up Blockers
The Mozilla Firefox pop-up blocker is integrated into the Firefox browser. To disable the pop-up blocker: Open the Tools menu .
How to disable popup blockers
How to disable the Firefox popup blocker (Windows PC). From the Tools menu, select Options. fierefox; From the Content .
pop up blocker for internet er
Pop-up Blocker for Firefox 3.01 - TechSpot OpenBoards
Is there an Alternate Pop-up blocker for Firefox? The built in pop-up blocker keeps allowing pop-ups through. I must admit it is not as good as .
Google Toolbar - Take the power of Google with you anywhere on ...
Privacy Policy · Requires Firefox 2.0 - 4.0.*. Share any web . Learn more. We're sorry, but Google Toolbar is only available for Internet Explorer and Firefox. .
Disabling Your Pop-Up Blocker
Pop-Up blockers are useful programs that block those anoying advertisements that pop-up . To totally disable the Firefox pop-up blocker, follow these steps: 1. .
How do I stop pop-up or pop-under Internet ads?
. 6.0 was because Firefox included its own pop-up blocker. . to adjust or change how Firefox handles pop-up follow the .
spyware removers free antivirus
Block Firefox Flash popups
Nov 15, 2005 . Some greedy advertisers have just figured out they can get around Firefox's popup blocking settings by launching popups from Flash. So, the .
How to Block Pop-Up Ads in Firefox « My Digital Life
Nov 2, 2008 . Like IE, Firefox can block pop-up windows and automatic image loading. . Blocking flash content not only blocks commercial ads from .
Pop-up Blocker options for Mozilla Firefox on Windows
Feb 25, 2011 . Solution: Adjust pop-up blocker settings in Firefox by accessing the Tools menu and . As a default, Pop-up Blocker is turned on in Firefox. .
popup blocker firefox
Enable or Disable Pop-up Blocker Using Firefox 3.5, 4, and 5
Aug 31, 2011 . Enable or Disable Pop-up Blocker Using Firefox 3.5, 4, and 5 . Learn how to enable or disable the pop-up blocker in Firefox 3.5, 4, and 5. .
Disabling Popup Blockers - Artstor Help
To turn off the popup blocker completely, uncheck the box next to "Block pop-up windows." Please note: Some versions of Firefox allow a .
For more information on the Yahoo toolbar please go to pop up blocker for apple.pop up blocker for mac
Pop-up Blocker Help
Pop-up Blocker in Google Chrome; Windows XP Pop-up Blocker Using Internet Explorer; AIM Toolbar; AOL Toolbar; Earthlink; Firefox; Google Toolbar for IE .
Options window - Content panel | How to | Firefox Help
Block Pop-up Windows: By default, Firefox blocks annoying pop-up windows on websites. Unchecking this optionpreference will disable pop-up blocking. .
For more information on the Google toolbar please go to popup blocker for firefox vista.
popup blocker for macintosh
Pop up blocker not working correctly on Firefox 8 | Firefox Support ...
Nov 23, 2011 . Since updating to Firefox 8, when I use a site that has a safe pop up that I allow, Firefox keeps blocking it even though I have asked it to make .
Mozilla Firefox Web Browser — Firefox Features
Firefox makes browsing better for you, bringing together speed, privacy and latest technologies. . Pop-Up Blocker . Or, find a happy medium: choose to view blocked pop-ups or create an "allow" list of sites whose pop-ups you're okay with .
Yahoo! Toolbar - Stay in touch with your world.
New User? Sign Up Sign In Help · Yahoo! Toolbar. Yahoo! Search WEB SEARCH . Toolbar is currently unavailable on this browser. Get Firefox 4 with Yahoo! .
Disable PopUp Blockers
Mozilla Firefox. Firefox blocks pop-ups by default. To configure Firefox's pop-up blocking: Open Firefox; Select Tools .
For more information on the MSN toolbar please go to pop up blocker for google chrome.
ad block plus plug in
Asa Dotzler - Firefox and more: say goodbye (again) to pop-ups!
Mar 31, 2005 . This is great to hear - that Firefox, who has had the best pop-up blocker, is staying ahead. (Opera 8, for instance, does a pretty lousy job .
Firefox: Pop-Up Blockers
Apr 27, 2011 . Firefox features a pop-up blocker that can prevent new windows from opening. Please follow the instructions below to be sure that new .


text:
Filtreaza hotelurile
Hoteluri in Texarkana (TX), Statele Unite (32 hoteluri)
Data sosire: 06 mai 2017 Data plecare: 09 mai 2017 Nopti: 3 Numar camere: 1 Camera 1: 2 adulti
Hampton Inn Suites Texarkana
4601 Cowhorn Creek RoadVedeti Street View Vedeti harta
Welcome to the new Holiday Inn Express Hotel & Suites Texarkana, Texas Looking for accommodations in Texarkana. The newly built Holiday Inn Express Hotel & Suites is ideally located near I-30, just four miles from downtown Texarkana and within minutes of local attractions and businesses. Families will enjoy staying at our hotel in Texarkana, Texas because our location makes it easy to visit Texark...
Holiday Inn Express Hotel & Suites Texarkana
4545 Cowhorn Creek RoadVedeti Street View Vedeti harta
You'll love the neighborhood-style living and great value of our TownePlace Suites Texarkana hotel. Our comfortable all-suite Texarkana, Texas hotel is near International Paper, the Red River Army Depot, Fulton Power plant, Cooper Tire, and the beautiful Perot Theatre. We're also a convenient stop between Dallas, TX, and Little Rock, AR. Our Texarkana hotel offers separate living and sleeping area...
Towneplace Suites Texarkana
5020 Cowhorn Creek LoopVedeti Street View Vedeti harta
Econo Lodge
4505 N. Stateline Ave.Vedeti Street View Vedeti harta
If you are coming to the area for business we are only minutes from Christus St. Michael Health Care, Cooper Tire, Red River Army Depot, Alcoa, Texas A&M Texarkana University and Wholesale Electric. While in the area be sure to experience world-class shopping at the Central Mall or visit the nearby Discovery Center Museum, Perot Theatre, Ace of Clubs House and Oak Creek Amish Furniture Store or ta...
Candlewood Suites Texarkana
2901 S Cowhorn Creek LoopVedeti Street View Vedeti harta
Whether you're traveling for business or pleasure, you'll love our Courtyard Texarkana hotel. Start your day with a freshly prepared, reasonably priced breakfast, chosen from our buffet or cooked-to-order. Stay productive with complimentary high-speed Internet access, an ample desk, comfy desk chair, and our 24-hour business center. Recharge in our indoor pool and fitness room. If you're planning...
Courtyard Texarkana
5001 North Cowhorn Creek LoopVedeti Street View Vedeti harta
The Hotel LaCrosse has an enclosed recreation center with an indoor heated swimming pool, hot tub, arcade, pool tables, children's play area, putting green, an exercise room and more. Our newly renovated rooms are furnished with a microwave, refrig, coffee maker, iron/board, hair dryer, alarm clock radio, and includes free HBO, WiFi, and high speed internet.
La Crosse Hotel
5100 North Stateline AvenueVedeti Street View Vedeti harta
Comfort Suites
215 Richill DriveVedeti Street View Vedeti harta
General Description: Close proximity to business district Local Attractions: Spring Lake Park - 0. 5 miles Museum of Regional History - 2 miles Recreation: Outdoor swimming pool Restaurants & Lounges: Nearby restaurant Services: Shuttle service is available Accommodation: 2 floors 132 guestrooms Policies: Pets allowed - contact hotel for details
La Quinta Texarkana
5201 State Lane AvenueVedeti Street View Vedeti harta
The popular Tex-Ark Antique Auto Museum is nearby as well, and boasts auto treasures sure to delight you with bygone memories! When you return to the Ramada from a day of business or leisure adventure, you can relax and retreat with the hotel services and features such as new 32 inch flat screen cable television with deluxe cable package, WiFi in all guest rooms, in-room refrigerators and microwav...
Ramada Texarkana
5401 State Line Ave Bldg AVedeti Street View Vedeti harta


text:
PlexiDor Performance Pet Doors 12.75 in. x 20 in. Large Bronze Door Mount Electronic Dog Door
- Model
- Internet/Catalog:
- 203378340
When the pet door application at your home requires the ultimate in convenience and security, the Plexidor PDE Electronic Pet Door is the choice of pet owners worldwide. The PDE hardened ABS panel slides effortlessly up and down like a mini electronic garage door. When the unit is inactive, the panel acts as security door keeping out unwanted guests. Using state-of-the art RFID technology (Radio Frequency Identification Device), the sensor reads the pre-programmed collar key code and opens and closes the door automatically for your pet only, while keeping other animals outside. The waterproof collar key weighs just 0.4 ounces and snaps onto your pet's collar. The door reads your pre-programmed key code as your pet approaches and when recognized, automatically opens and closes the door allowing access for your pet. You can set the unit to control the timing of how long the door remains open. The Plexidor PDE Electronic Pet Door plugs into a standard household outlet or can be hardwired. Easy to program and even easier to use, the Plexidor Electronic Pet Door will provide years of enjoyment for your family and pet.
- For cats up to 24 pounds and dogs up to 125 pounds
- Pet and child safe - won't close when obstructed
- Door is always securely locked with stainless steel rod when not active
- Collar key opens and closes the door automatically for your pet only - no batteries required
- One touch programming, easy to add or change 1,000s of different codes
- Set the timing of how long the door remains open
- Won't interfere with underground fence or home security systems
- 5-Year residential warranty
- Manufactured in the USA
- Opening: 12.75 in. w x 20 in. h
- Cut hole: 14.25 in. w x 21.5 in. h
- Interior frame overall: 17.125 in. w x 54.625 in. h
- Exterior frame overall: 17 in. w x 24 in. h
- Click here for more information on Electronic Recycling Programs
- Door Thickness (In.) :
- Max Thickness 1 3/4 Inch
- Electronic :
- Yes
- Lockable Flap/Panel :
- Yes
- Maximum Pet Weight (lb.) :
- 125
- Pet Door Mount Type :
- Door Mount
- Pet Door Opening Width (in.) x Height (in.) :
- 12.75 x 20
- Product Depth (in.) :
- 1.75
- Product Height (in.) :
- 54.625
- Product Width (in.) :
- 17.125
- Returnable :
- 90-Day
- Type :
- The Plexidor Electronic Pet Door acts as a mini electronic garage door for your dog or cat. The PDE Electronic Dog Door uses RFID technology to open and close the door automatically for your pet only.
Ratings & Reviews100% of customers recommend this product
- A must have for homes with large (or small) pets
December 24, 2013
- Verified Purchase & Recommended Product
As I am not a handy person, we had a pro installer do installation & it seemed not too difficult. Took about an hour or less. The door looks great and it is so terrific to have--the dog can come and go as he pleases. Best of all Made In America!Pros Energy Efficient, Sturdy, Functional, Well Made, High Quality Cons definitely on high end of price but worth it.
PamelaTexas, USA
45 to 54, Female
Shipping & Delivery OptionsShipping options for [zipcode] (change)
Arrival dates and shipping costs shown above are estimates.See exact dates and costs and select your preferred shipping option during checkout.
Express Delivery from Store is available for items currently in stock at a The Home Depot store within a delivery ZIP code. A driver from a local store will deliver the item(s).
Outside Delivery: Service includes delivery to area outside the house which is accessible by delivery equipment.
Threshold Delivery: Service includes delivery across your first doorway or threshold (ie. garage, backyard, deck, first room of the home).
This item cannot be shipped to the following state(s): GU,PR,VI


text:
Olympic National Park
Olympic Peninsula, WA
Olympic National Park is a land of beauty and variety. Created in 1938 to protect the Roosevelt elk, primeval forest and wild coast, the park encompasses nearly one million acres. A few days of exploration take you from breathtaking mountain vistas with meadows of wildflowers to colorful ocean tidepools or early homestead cabins. Nestled in the valleys are some of the largest remnants of ancient forest left in the country. Trees can tower here 300 feet tall, and the forests range from the westside's lush temperate rain forest to dry, fire-shaped eastside forests. Olympic is like three magical parks in one. Take time to explore all of its faces.
Wilderness Coast Olympic National Park includes 73 miles of wild coastline. These beaches offer a glimpse into an environment that local tribes have called home for generations. Short trails or overnight backpack trips offer ways to explore the rugged coast and its teaming tidepools.
Ancient Forests Towering trees and rushing water greet visitors to Olympic's old growth forests. Lake Crescent, Heart O' the Hills, Sol Duc and Elwha offer old growth forests on the northern peninsula. Staircase is a popular eastern destination. The westside Quinault, Queet, Hoh and Bogachiel valleys are superb examples of temperate rain forests.
Snowy Mountains Head to Hurricane Ridge for vistas of the rugged Olympic Mountains. A winding 17-mile paved road climbs from Port Angeles to the nearly mile-high Hurricane Ridge Visitor Center. On a clear day the park's mountainous interior and the Strait of Juan de Fuca and islands to the north are visible. The steep, dirt Deer Park Road (east of Port Angeles) also leads to the mountains and a small campground. This winding road is not suitable for trailers and RVs.
Read the "Hit the Slopes this Winter!" blog here.
|$5.00 - $15.00
|about 4 hours
The Olympic National Park is open 24 hours a day, 365 days a year, although some roads, campgrounds and other visitor facilities close in winter. Emergency situations including flooding, blowdowns or wildland fire may also close areas temporarily.
|Free Parking
Visitor Reviews
Tuesday April 17, 2012
I use Seattle as my base for exploring the entire area. I especially like ferrying to the San Juan Islands and to the Olympic Peninsula and visiting Olympic National Park.— Jim
Thursday December 15, 2011
Myself and 3 of my girlfriends decided to do a 10 day camping trip in WA. We packed up all of our camping gear and UPS'ed it across the US. We live in South Florida so it was literally across the US. We started our adventure in Seattle. Then the next morning we headed North to San Juan Islands and went kayaking in the beautiful blue waters. After that we camped again and the headed to the Olympic Penisula and spent 4 days there. We went white water rafting, hiking and just looking at the flora and fauna and the gorgeous Northwest. We ended up at Mt Rainier to start the close up of our journey. Then we headed back North to Seattle. We were able to visit the SAM as well as eat at the Space Needle. I love WA and the beauty that it has to offer. Seattle is such an amazing city with so many things to see and do. Wish I could have spent a month there just to make sure we were able to get everything in. I highly recommend a camping vacation with the girls for an awesome adventure. Can't wait to head that way again.— Jamie


text:
Filter Results:
Publication Year
Publication Type
Publication Venue
Key Phrases
Learn More
- Daniela Linhares, Tiago Jacinto, Ana M Pereira, João A Fonseca
- Clinical and translational allergy
- 2011
BACKGROUND Atopy and rhinitis are among the factors affecting exhaled nitric oxide (FeNO) values and may contribute to difficulties in the clinical interpretation of FeNO measurements. However, data assessing their effects on FeNO values had never been summarized. This review aims to evaluate the effect of atopy and rhinitis in FeNO values in otherwise… (More)
BACKGROUND Allergic rhinitis and asthma (ARA) are chronic inflammatory diseases of the airways that often coexist in children. The only tool to assess the ARA control, the Control of Allergic Rhinitis and Asthma Test (CARAT) is to be used by adults. We aimed to develop the Pediatric version of Control of Allergic Rhinitis and Asthma Test (CARATkids) and to… (More)
- ‹
- 1
- ›


text:
- sort by:
73 houses for sale within 5 miles of Hindhead (Surrey)Did you mean?
- Check you have entered the location correctly.
- Alternatively enter another alternative location or adjust your search criteria.
- If 'no results' continues to show, we may not have any properties for sale in your desired location.
2 Bedroom Semi Detached House For Sale
Beacon Hill Road, Hindhead, Surrey, GU26
A modern two bedroom semi detached cottage built in 2000. Situated in the heart of the village, with accommodation arranged over two floors. The property has been much improved by the current owner to provide immaculate presentation throughout.
4 Bedroom Detached House For Sale
Grove Road, Hindhead, Surrey, GU26
An individual detached family home providing versatile accommodation arranged over three floors. Situated close to the centre of the village with pleasant views over playing fields.
4 Bedroom Detached House For Sale
Golf Links Avenue, Hindhead, Surrey, GU26
This four bedroom detached house is set within a tucked away position in Hindhead, enjoying picturesque views over the valley and towards the golf course.The surprisingly spacious accommodation consists of a generous reception room which makes the most of the view to...
6 Bedroom Detached House For Sale
Churt Road, Hindhead, Surrey, GU26
A handsome Edwardian house of impressive proportions, enjoying the benefits of the architecture of the period with large well proportioned rooms.
4 Bedroom Detached House For Sale
Stoney Bottom, Grayshott, Hindhead, GU26
A charming 4 bedroom detached house believed to date back to 1912. The property has been extensively re modelled over the years to provide practical yet versatile family accommodation arranged over two floors, enjoying a rural aspect adjoining National Trust Woodland.
4 Bedroom Detached House For Sale
Whitmore Vale, Grayshott, Hindhead, GU26
A beautifully appointed detached house and separate annexe, situated in a wonderful tranquil country setting in grounds of 1.74 acres.
4 Bedroom Terraced House For Sale
Royal Huts Avenue, Hindhead, Surrey, GU26
This spacious four bedroom town house is situated within a quiet no through road in Hindhead. Presented in good order throughout, the flexible accommodation comprises a large kitchen/diner with double doors leading to the garden, a well proportioned living room, four...
6 Bedroom House For Sale
Old Barn Lane, Churt, Farnham, GU10
EQUESTRIAN - A beautiful and historic country house of immense character set in gardens and grounds of approximately 5.9 acres with far reaching views over the Wey Valley
4 Bedroom Detached House For Sale
The Martins, Hindhead, Surrey, GU26
This substantial four bedroom detached house is prestigiously located within a private gated development of just six houses. Built to a high standard in 2015, the property benefits from being in immaculate condition throughout, and with many modern additions. The...
4 Bedroom Semi Detached House For Sale
Hindhead Road, Hindhead, Surrey, GU26
This charming attached character cottage is located in Hindhead and is situated in a semi rural location with gated access to the Devil's Punch Bowl National Trust common land and within easy reach of Haslemere Mainline Station.The property offers flexible...
- sort by:
- Single Property
- Multiple Properties


text:
Video: YouTube Dailymotion Metacafe Vimeo
Photo: Google Images Flickr Photobucket SmugMug
Reviews: Rate Your Music Metacritic Sputnikmusic Pitchfork NME
Lyrics: LyricWiki LyricsFreak
Tabs: 911Tabs Ultimate-Guitar TabCrawler Chordie Songsterr
Covers: FreeCovers SeekaCover
Blogs: Hype Machine
Official Site Wikipedia MusicBrainz Discogs All Music Guide Last.fm Yahoo! Music
Arsenal on iTunes Arsenal on Amazon
There are 7 artists by the name Arsenal. 1: Arsenal is a Belgian music band formed in '99 by Hendrik Willemyns & John Roan. The music of Hendrik Willemyns & John Roan delivers a smoothly produced lounge funk, and first appeared with the EP RELEASE from '99. 2: Arsenal was the first jazz-rock band in the Soviet Union, formed in 1973 by Alexey Kozlov. Between 1978-1991 the band released 6 LP's, which were later reissued by Boheme Music as a four-CD box set, Scorched By Time.


text:
Who We Are
Learn more about New Hope Housing and the lives impacted.
NHH at Harrisburg – Spring 2017 Update
See the exciting progress we have made on our New Hope Housing at Harrisburg mixed-use development.
History of New Hope
Enjoy this brief video about New Hope's founding through the power of philanthropy and with impetus from the People of Christ Church Cathedral-Episcopal.


text:
The Garmin FR70 will help you to stay motivated after the New Year's Resolution glow has worn off. The Garmin FR70 is super sleek, and allows you to track your time, heart rate, and calories burned. In the gym or on the road, the FR70 tracks all your work out data, including time, heart rate, calories burned and more. At the heart of its success is the FR70s wireless ANT+™ technology, which allows it to connect to other ANT+™ compatible devices. Track your weight, body fat, body water, and six other measurements with the FR70, when used with the Tanita BC-1000 body composition scale (sold separately.) The FR70 connects wirelessly to a heart rate monitor, which provides instant feedback about how heart your heart is working. Once your workout is finished for the day, the FR70 automatically transfers data to your computer (Windows or Mac) wirelessly when in range.What's in the Box:
Technical Specs:
|Garmin Forerunner 610 W/HR Monitor
|Garmin FR70
|$99.99 - $130.00


text:
Use the frameworks and tools you love, with Composer managing all of your app dependencies.
Create apps, connect databases and add-on services, and collaborate on your apps, for free.
Let Heroku maintain and patch your runtimes, including PHP 5.5 and the HHVM beta.
Go from code to running app in minutes. Deploy, scale, and deliver your app to the world.


text:
2605 Delta Dr
Colorado Springs,
Your search for reliable motorcycle parts, motorcycle accessories and motorcycle engines ends at Action Cycles & Leather. Located in Colorado Springs, CO, we have been serving the motorcycle enthusiast for over 37 years. Our store stocks new parts, used parts, quality used motorcycles, clothing and accessories to make your riding experience the best it can be. We offer: Dirt bikes Dual sport motorcycles Sport bikes Off road vehicles ATVs New and used parts Clothing and accessories At Action Cycles & Leather, we also buy used motorcycles, ATVs and motorcycle parts. Our store stocks tons of motorcycle parts, import motorcycle parts and accessories. Call Action Cycles & Leather today to learn more about our products and services.
Provided by Yellowpages.com
If you've been to or used
Action Cycles & Leather, leave a review.
It's easy, only takes a couple of minutes and you'll help thousands make an informed decision.


text:
Online Golf Game - Verti Golf 2
Verti Golf 2 is a new incredible Shockwave 3D golf game based on games such as 'Crazy Golf' and 'Mini Golf'. It is very similar to the Verfi Golf game, however, it is a newer version of it. This exciting and addicting game has extraordinary dynamics that entice you to play this game over and over again. There are no special rules. The game should be played according to typical golf rules; the player needs to putt the golf ball in as few shots as possible. Have fun Golfer!
How to Play: Left click using your computer mouse and hold it. Aim and adjust the angle for you shot by moving the mouse around. Then, press the 'Spacebar' and hold it. The longer you hold the 'Spacebar' down, the more powerful your golf swing will be. Release the 'Spacebar' key to hit the golf ball.
FREE Download PC/Windows Enhanced graphics and game play, a must try! Play offline any time. Download
Get The Full Unlimited Version. Unlimited play, 100% safe ordering, risk free 60 day guarantee. Order Now


text:
|Version 1 HD Video
|Version 2 Stagevu.com
I wanted to see this film from the moment I read its TIMES' summation: a sheepish night-club manager shows up for work at his new Liverpool job, and discovers his predecessor, as a kiss-off gesture, has scheduled Catholic and Protestant Irish social groups for the same night (he also saved some tables for mental patients, having a night-out). The evening's entertainment features a thrash-band screaming lyrics like "YOU'RE GONNA DIE-- DIE--DIE!" at the golden agers, a catatonic magician.....The rookie sets out to get through the impossible night ahead. The accents are fuzzy, and some of the Irish jokes obscure-- but this film is so filled with talent that wonderful Bernard Hill takes a second-tier role as a dim bulb. The film's moral center is that remarkable character actor Ray McAnally, a detective trying to find a real criminal among all the low-lifes. Few people have voted on this film-- but a lot of them accorded it a 10. Scout around and discover why-- this is one singular film.


text:
On occasion India-Hotels.ws may revise this Privacy Policy to reflect changes in the law, our Personal Data collection and use practices, the features of our Site, or advances in technology. Therefore, you should review this Privacy Policy periodically so that you are up to date on our most current policies and practices.
India-Hotels.ws may disclose private Data to protect ourselves against liability, to respond to subpoenas, judicial processes, legitimate requests by law enforcement officials, or as otherwise required in order to comply with applicable law, or to the purchasers in connection with any sale, assignment, or other transfer of all or a part of our business or company.


text:
|Reviews for persian Devil
| DeansSammy chapter 14 . 12/4/2012
Loved the whole story.
| Naimeria chapter 14 . 10/22/2010
I just read through this and loved it! Your characters were very intriguing and engaging. I found myself loving Ann for some reason. The plot was very good too; kept me wanting more.
And, limp Sam is always the best. ;D
Thank you for writing such a lovely story!
| Angela chapter 5 . 9/26/2010
Ok i love this story, but i suggest you get a beta reader, since english is not your first language it would help with some of the mishaps in wording, but still loved the story great job!
| CeCe Away chapter 14 . 6/30/2010
I read the entire thing all the way through and enjoyed it very much. You're a good writer.
| Lujayn chapter 14 . 6/22/2010
Great epilogue! I'm glad Sam is getting better and the boys are back on the road:)
| HSMSupernatural chapter 14 . 6/14/2010
Great Chapter! Great Story Too! Loved The Ending Wasn't Expecting That At All! Can't Wait For Another Story From You!
| ritsam chapter 14 . 6/13/2010
Very enjoyable final chapter, but honestly I wish, if I could read some more fainting Sam in this chapter. You wrote, Sam now could walk without passing out...if you wrote that down a little elaborately, it would's been great.
Anyways, glad Sam's okay now and back on his feet. I'll waiting for another limp Sam story of yours.
TC, Ritz.
| Jasmineisland chapter 14 . 6/12/2010
Great first story! Write another one soon.
| ephiny63 chapter 13 . 6/8/2010
Hey honey
I have just finished reading the last three chapters, trying to catch up big time ;0)
You have done a great job in wrapping up things without dragging it out too much. I liked the fact that you kept the tempo or pace up between chapters, it made it to be very compulsive reading. As the reader I wanted more and wanted it quickly which is what you gave. Your writing has improved so much, and I really liked Mary's dad he was pretty cool.
I'm looking forward to reading the epilogue and then on to your next story ... coz you can't stop now!
hugs Shelley
| HSMSupernatural chapter 13 . 6/7/2010
Great Story! I Do Hope You Continue It! Can't Wait If You Do!
| HSMSupernatural chapter 12 . 6/7/2010
Great Chapter! Hope Sammy Gets Better! Going To Read The Next Chapter Now!
| ritsam chapter 13 . 6/6/2010
Well, no thinking. You should write an epilogue. Without a closing part, this story would be an incomplete fic. Anyways, great chapter. Mr. Aria's chanting part was creepy and I thought I'd lost Sam. But...uhhuh! He's okay yay...OTG!
Love it,
| ritsam chapter 12 . 6/6/2010
Due to some reason, I didn't get the alerts. Hotmail sometimes acts like a you know! yeah...you've got that right! I din't even get my own review alerts too! *screams* Thank god my freaky id's working again.
My God, Sam's so sick and I don't like where this story's heading. But...as I know you don't write death fics... that means, I can read the next chapter of yours.
Onto the next installment.
| Lujayn chapter 13 . 6/6/2010
Phew! I'm so glad Sam is getting better. Dean would absolutely do anything for Sam. Of course you should write the epilogue! The story is wonderful so yeah, I'm gonna be waiting for an epilogue;)
| NetMyne01 chapter 13 . 6/6/2010
Please write an epilogue!Great story, loved it very much.


text:
I attended this with my sister, brother-in-law, and baby niece in May 2016, and had a great time! Erik is hilarious, so I'm surprised other people weren't laughing, but maybe they... read more
The tour is currently seasonally closed. The first tour of 2017 will be on...
The tour is currently seasonally closed. The first tour of 2017 will be on Friday, May 5th at 11am.
From May 5th until November 1st, 2017, there will be a Free Tour of Portland every single day of the week at 11am.
For a full schedule of the 2017 tour season, please see the "Tour Calendar" page of our official website.
Think of this tour as stand up comedy about Portland's weird and wacky history and culture. Sure to have you laughing the whole way through, this is without question the most entertaining walking tour in town! Come find out why local comedian Erik Kennon's Free Walking Tour is so much more fun than one that costs $20 up front!
The Free Tour starts everyday at 11am on the sidewalk of SW 6th Ave in front of Pioneer Courthouse (across the street from Pioneer Square and the Visitor Information Center.) No reservation necessary! Just show up! The tour meets 7 days a week, rain or shine :-) Look for Erik, who will be wearing his signature neon green "Free Tour" t-shirt. The tour is about 2 to 2.5 hrs long and ends in front of Voodoo Donuts, Chinatown, and the Saturday Market. You'll receive insider tips on restaurants and nightlife, and lots of photo ops! Your guide works for tips- you can be assured of the highest quality!


text:
Hello all,
Brief overview, then the logistics:
I had UM3Xs for around two to three years. Eventually, as all products do, they wore out and the tip fell off.
Contacted Westone and they were very helpful. Unfortunately, due to turn around times between AU and USA, I no longer require the new version of them that I received early this year. I can drive to my new job and don't need public transport anymore plus I have bluetooth IEMs for gym (Not that cruel a person as to torture these poor IEMs anyway).
So, they sit.
They sit and look pretty in their orange box.
Now are these for you?
Probably. They're made for live stage monitoring. Everyone calls them 'flat'. I'd say they push down the higher frequencies that don't make it into live content and 'compliment' the prominent lower mids that live sound is comprised of. Guitars and male vocals are great. Michael Akerfeldt and his PRS will melt your mind. Separation is excellent for me, sound stage a little tight.
Prefer a local pick up in Brisbane, Australia- But i'm not sure Head-Fi is specific enough for my region.
I'll post Australia wide inclusive of the asking price. They'll be insured and trackable. World wide, have at it. Give me some details to work with and i'll let you know shipping costs. Paypal only..
Edited by Tetsuma - 5/12/15 at 5:29pm


text:
The tour...
...Having a "local" show you around is certainly the way to go!
We are based at Muriwai Beach, west Auckland, (just 40 minutes from Downtown Auckland). Many tours visit this region, but we are the tour that LIVES here! As our family were the early pioneers to this area, settling here in 1922, we know this region best, so we choose to focus our tours solely on this area. We have our guests not only "become part of our region", but we are are able to give back to our local community, thus maintaining our sustainability. We also plant a Native tree in our farm's own Reserves for every tour we run.
You cement your tour by having a tree growing in our community, and we make the tour you take with us Carbon Neutral.
This tour are "un-hurried" (unless you require to get back to the city by a certain time). Our tours also have minimal walking, so are ideal for SENIORS or people that need a tour at a slower-pace!
We have had wheelchairs and folk on walkers... (so as long as you are able to get in and out of our vehicle that's OK).
and certainly NO eating your lunch on the bus !
>> Are you are disembarking a Cruise and have luggage? No worries! We will gladly carry it with us on your tour...and should you be flying back home, we can even transfer you to the Airport for a small extra charge!
Please note that Auckland Private Tours operate by request, and that prior bookings are essential to guarantee availability.
Our tour ONLY operates around the west Auckland region
- a PRIVATE tour means your booking is for you ONLY -
The *private* tour price is quoted on an individual basis
If you do NOT WANT A PRIVATE tour, please visit: http://www.aucklandshoreexcursions.com which will give you the option and price for our NON-private (traveling with others) tour.
ANY or ALL of these stops on the map below are available
1) Craftmarket
2) Wine Tasting
3) LUNCH - (usually at Soljan's winery).
4) Muriwai Beach & Gannet Colony
5) Our Sheep Farm & Homestead (with HONEY tasting, touching sheep, woolshed tour, carbon offset tree, and afternoon tea).
We are the ONLY *private* sheep farm within 40 minutes of Auckland that you can visit on a TOUR
LUNCH (with wine/beer) is included in your tour price and is your choice from the menu at a local upmarket cafe/restaurant. Vegetarian dishes available!
AFTERNOON TEA is also included, and is NZ's most famous dessert called Pavlova
Visit our Auckland Shore Excursions website which specialises in a Shore Excursion tour.
YES, this tour can be made PRIVATE too!


text:
Tattooed Mare. 3K489. Papers in hand. 15 hands. Clean legs. Smooth. Easy to handle. Will not break. Currently traveling about 20 mph and getting better…$2,800
Fun, Safe, Sweet! Kid friendly lead changes. Local show miles. Cute mover, hack winner. Easy keeper. Used in lesson program for advanced beginners…$12,000
9 year old Bay Appendix Mare who needs a lot of time of the day. She is very energetic and loves to run. I don't have enough time to work with her no more…$500
Nova is a gorgeous black 10yr old sport horse mare with tons of show miles eventing with her senior rider. They were High Point Division Winner GAG with…$12,000
14 Year old gelding paint for sale! Loads, trailers and stands for farrier, Stays in cross ties. Good with a simple snaffle. He has lots of energy, he…$5,000
7 year old Son of Davinci de los Reyes elegant walk. Professionally Trained. Need to be ridden, loves to work. having a baby that's why I have to sell…$9,000
16HH, 6 Year Old, Exceptionally well bred KWPN 16hh for Eventing, Show jumping or Dressage. Korlanda also know to us as Kora is a very eye-catching…$13,500
2010 Premium Oldenburg mare by sired by Silver Lining, aka Landwerder, (Landadel / Godehard / Furioso II) was a successful hunter, jumper and dressage…$25,000


text:
The Second Hand Marching Band was a band of 16ish people from Glasgow and Edinburgh and thereabouts who play untraditional big band folk music with brass, woodwind, guitars, mandolins, ukuleles and accordions.
Over the many members to pass through the ranks we have had members of such bands as Eagleowl, The John Knox Sex Club, The Tannahill Collective, The Just Joans, Dananananaykroyd, How To Swim, Q Without U,Benni Hemm Hemm, The Lula Maes, The Martial Arts, Wall Street Ammunition Hero, Freight Logistics,Two Wings,The Trembling Bells and The Belle Hops.
SHMB formed in the autumn of 2007 and released two EPs (Dance to Half Death, Grit and Determination), a compilation (Compendium), two albums (Hurricane, Thunderstorm and Faults) and a single (We Will Convince You).
Artist descriptions on Last.fm are editable by everyone. Feel free to contribute!
All user-contributed text on this page is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply.


text:
+ Locations, Office Hours & Directions
Dr. Brad Starkey is an anesthesiologist in Oklahoma City, who manages patient pain levels before, during, and after surgical procedures.
We invite you to write a review about your experience with Dr. Starkey.
5101 W Memorial Road, Oklahoma City, OK 73142-2018
|Doctor Specialty
|Practice Specialty
|Multi Specialty
|Languages Spoken
|3 See them all
|Doctor's Specialty
|Doctor's Title
|Practice Specialty
|Multi Specialty
820 Nw 13th Street, Oklahoma City, OK 73106-6898
|Doctor Specialty
|Languages Spoken
|2 See them all
|Doctor's Specialty
|Doctor's Title
NOTE: Please contact the doctor's office to confirm your coverage before making an appointment.
Dr. Brad Starkey graduated from University of Oklahoma College of Medicine in 1994.
Dr. Starkey has two offices in Oklahoma where he specializes in Anesthesiology.
Dr. Starkey works with three doctors including Dr. Stephen Kelly and Dr. Graciela Gallardo.
As an anesthesiologist in Oklahoma City, OK, Dr. Starkey ensures patients are free of pain before (pre-op), during, and after (post-op) a surgical procedure. By administering anesthesia, Dr. Starkey ensures that patients do not feel the pain of a surgical procedure.
Please Note: The information displayed below is sourced from the 2014 Medicare Physician and Other Supplier National Provider Identifier (NPI) Aggregate Report. It's important to remember that the statistics below are not inclusive of all patients treated by Dr. Starkey, but only those who participate in Medicare.
Read the most recent articles about Anesthesiology
See our Privacy Policy and Terms of Use.


text:
A Miami Beach homeowner has been treating snowbirds like pesky starlings, blasting them with reggae music and training a searchlight on their boats at night to drive them off when they anchor behind his $5.3 million mansion. Seeking peace and quiet and a protected overnight anchorage, Jennifer Rider and Al Holden anchored their 34-foot Marine Trader, Close Knit, May 3 behind the estate on Sunset Lake while making their way to the Florida Keys."We had talked to a few people and they said it was a good little anchorage" — well-protected, on a small lake off the Intracoastal Waterway — "though we might have some trouble with a homeowner at one end," says Rider, 53, of Kingston, Ontario.They didn't know which end that was when they dropped the hook. "We didn't go there looking for trouble," she says. Trouble, however, found them.
Thanks to technological advances, small-boat skippers today can venture 20 or more miles offshore. Outboards are more reliable, and sophisticated electronic navigation and safety equipment is easy to use.
With a pair of new 4-strokes, a GPS/chart plotter, radar and VHF radio with digital selective calling, why not take your 23-footer 40 miles offshore? All of the high-tech mechanical and electronic technology that boaters rely on has something in common, though: It needs electricity to function, which means proper maintenance and care of a boat's electrical system has become much more important.
• Carry spare parts, such as wire and electrical connectors, fuses, bulbs, engine belts, distilled water for the batteries and engine fuel filters.
• Carry electrical tools, such as crimpers, a wire cutter and a voltmeter.
• Be sure all battery terminals are tight, clean, corrosion-free and sealed against moisture.
• Avoid using wing nuts for battery connections because vibration can loosen them and they are difficult to adequately tighten. Use nylock hex nuts. Loose connections create resistance arcing and heat, and can lead to overheated wires and possibly a fire.
A container ship and a fishing boat collided in May at night in a ship's channel eight miles south of Gulfport, Miss., with the loss of three of the fishboat's 16 crewmembers — another tragedy that raises concerns about ships steaming through waters where fishing vessels are at work.
The 660-foot Eurus London, en route to Freeport, Texas, with a load of bananas, and the 163-foot Sandy Point collided about 8:45 p.m. May 18 in the cut between Cat Island and Ship Island on a night that was dark but not foggy, the Coast Guard says. The Sandy Point, a menhaden boat based out of Omega Protein Corp.'s processing plant in Moss Point, Miss., took on water and sank.
The March 2009 sinking of the fishing vessel Lady Mary off Cape May, N.J., with the loss of six crewmembers inspired a 20-page Pulitzer Prize-winning newspaper account of the tragedy and, with the loss of five other fishermen off New Jersey in 2009, raised an alarm that helped push far-reaching fishing vessel safety measures through Congress.
Page 17 of 30


text:
My Content
Membership has its privileges! Sign up or sign in to gain full access to both All About Jazz and Jazz Near You. Learn more.
Track Listing: 1.Blood And Body 2.Before The Sermon 3.Going To Church
Personnel: Roy Campbell: trumpets
We need your help and we have a deal. Contribute $20 and we'll hide the six Google ads that appear on every page for a full year!


text:
0 Members and 1 Guest are viewing this topic.
Oi! You! Yes you with the wooly coat and high heels. Stop playing with your conkers in public. Conkers are the fruit (well, nut actually) of the Horse Chestnut tree. Like other fruits they will differ in size according to the ammount of water and nutrients available.
Those are cool seeds do they dry hard .. are they poison...I have never heard of a Horse chestnut tree! Very cool!They look a bit like wild cu CUM bers? LOL....Stop playing with those babies right now you naughty Sheepy! LOL
I used the term 'fruit' losely.The green spiny shell of the tree usually conatins two seeds (conkers) which I am sure are classified as nuts. Pop one in a pot, and you will have your own personal supply of conkers. Though it might take a while before you reap the benefits of your cultivation.Karen Yes, unlike the Sweet Chestnut, these are toxic. BTW the Horse and Sweet chestnut are not related.


text:
|Version 1 HD Video
|Version 2 vidbull.com
|Version 3 vodlocker.com
|Version 4 vid.ag
|Version 5 thevideo.me
The idea for "Kung-Fu Master" was proposed by Jane Birkin in Agnès
Varda's tribute documentary to her, "Jane B. par Agnès V." (1987).
Birkin suggests a film in which a 40-year old woman would fall
hopelessly in love with a teenage boy, suggesting herself and Varda's
and Jacques Demy's son, Mathieu, for the leading roles. That very same
year, the idea would develop into the rapturing, bewitching, winning
"Kung-Fu Master", a film unlike any other ever made.
Mary-Jane (Birkin), 40, divorced, independent, living with her two daughters (her real-life daughters, 16-year-old Charlotte Gainsbourg and 5 year-old Lou Doillon), suddenly finds herself terribly attracted to one of her daughter's schoolmates, 14-year-old Julien (Mathieu Demy), and vice-versa. From then on, Mary-Jane and Mathieu find the unlikeliest ways to meet (including Mary-Jane bumping her car on Julien on purpose!) as they face love's highs and lows, trying to make it thrive against society's ponderous prejudices and Julien's own inevitable "growing up".
The film is a hoot from start to finish. The title is a reference to the Arcade video game, where a Kung-Fu Master must endlessly fight increasingly dangerous obstacles and enemies (as must Julien and Mary-Jane) to save his captive sweetheart, who is kept tied up, perennially crying for help. The opening sequence of the film, in which Mathieu Demy in full Kung-Fu costume skilfully simulates the robotic choreography of the video game hero is delightfully funny and wins you at once. The dialog sparkles with jeux-de-mots and a mix of English and French sense of humor.
Jane Birkin was probably never more beautiful or appealing than here, her angular, bony beauty serving her emotional transparency and complete commitment to her role. Mathieu Demy, inexperienced, is nevertheless charming, well-cast and never phony in his difficult role. Varda's direction of her own son is amazing: it looks as if she's discovering his acting potentialities and the first signs of manhood along with Mary-Jane and ourselves. The cast includes Birkin's family (parents, siblings, nephews, daughters etc), who appear nonplussed with the touchy issue and ultimately even help the odd couple. Charlotte Gainsbourg shines with her urchin face, special talent and sensibility; she's a natural. Baby Lou Doillon is lovely throughout, adding to the feeling of spontaneity that gives the whole film a slightly magical touch, as if we were watching improvised scenes, not scripted ones. Mary-Jane's and Julien's scenes together are far from risqué, but filled with emotional rapture, originality, humor. Sex is implied, but never at the core of things; love -- romantic, throbbing, unconventional love -- is.
"Kung-Fu Master" is a fable about the nature and possibilities of romantic love in obtrusive circumstances, and MAYBE it hints that women, girls and boys are better suited for it than grown-up men (which is probably true!). When Mary-Jane and Julien go to a desert island so that they can fully experience their love far from society's burden, we can see why they're at once sacred (they're pure, unbiased by interest, conventions, hypocrisy) and doomed (their love can only exist fully and freely away from conventional society). The film's ultimate goal may be to translate women's infinite, inexhaustible talent for loving and teaching love, regardless of how unlikely the object of their love is, or how powerful the enemies, or how complicated the obstacles; women are the invincible, undisputed Kung-Fu Masters of love, even if/when they don't win.
This is arguably Varda's and Birkin's finest hour; they have made a film that is a triumph of poetic sensibility filled with humor and intelligence; it's a tribute to feminine pride (no man could EVER make a film like this). Enchanting from start to finish, always surprising, never tacky or schmaltzy, "Kung-Fu Master" is a one-of-a-kind film just waiting to be (re)discovered -- but most likely destined to be locked away, in these hypocritical PC times of ours that furiously prevent renewed access to films as brave as this unless they're scandalous (which KFM is not). If you can find it, do see it by all means: and pay special attention to the beautiful, subtle, rich finale. Beware, though: "Kung-Fu Master" may be hazardous to your cynicism and conventionalism, and may restart your belief in l'amour fou.


text:
StrongLoop, Node.js and the API Economy – Interested in Joining Us?
Are you looking for your next move? Do you want to move into the API economy? Can you write Node code? Look no further – I'm hiring! Listen up.
Back in 2014 Gartner named StrongLoop as a "Cool vendor" in its published report on Cool Application vendors. Yes, Gartner does indeed publish such a report – see for yourself here: "Cool Vendors in Application Development, 2014."
It's been over a year since StrongLoop was acquired by IBM and became part of IBM Cloud, and I'm proud to say we stayed cool! Our processes stayed cool and improved – we are Agile, have adopted the best of the Spotify Engineering principles, and have the ability to turn on a dime. Sound like a startup? Well, to be honest it feels like we never left a startup! The team expanded, the product blended into IBM's API Management products and re-launched as API Connect with great success and traction in the market. We adopted new and modern communication tooling, worked on cutting-edge technology, re-drew the lines and with continuous improvement and iteration we lead the way in providing full life-cycle solutions for the API Economy.
I'm excited to say that Forrester Research has recognized IBM as the leader of the pack with a strong Offering and equally strong Market presence! See the diagram below from the report. You can download the full report here:
So what does it mean for you? Well, read on!
Node.js is proving to be the forefront of this digital transformation, from fueling the growth of the API economy to revolutionizing infrastructure with serverless applications. And as one of the founders of the Node.js Foundation, we are committed to the advancement of Node.js and its thriving ecosystem such as Express and LoopBack, amongst others. Our developers contribute significantly to open source development, and you will contribute significantly to authoring next generations of LoopBack, a framework for creating your APIs and microservices.
If you love to work with smart minds and next generation cutting edge technologies, the IBM StrongLoop team is looking for Node.js rockstars to join our team. We have several openings for Software developers. You will get to pioneer Node.js projects with a growing team creating Enterprise grade solutions for the API economy. You get to work in an agile fast-paced startup environment, yet backed by the power of the most forward-thinking enterprises today.
Drop us a note at firstname.lastname@example.com or firstname.lastname@example.com! You can also look at our other opportunities here.
We're looking forward to hearing from you!


text: Pawn Stars Drive a Hard Bargain. Click to block a category:GamingPoliticsNewsComicsAnimeOther scopene next random Comment Top NextComment Ideas? Comment with them and I will dedicate the next one to you! next Tags: pawn | stars WI] RENAME [ ARK? ABRAHAM [, WP AM] A PEPSI mun NUMBER Will Hill THE soon. I' ll Bucks WE ( Ili) WAS Ill? EXPERT ll [EARS ... +686 Views: 20395 Submitted: 09/13/2010 Facebook Twitter Google+ Tumblr Pinterest


text:
Surface Preparation And Coating
Reckon with us, if you want to avail the best in class Surface Preparation and Coating service at the astoundingly affordable prices. We are referred as the significant entity for rendering the Surface Preparation and Coating services from Haryana, India. Our competent professionals make painstaking efforts to meet the industry stated standards as well as the aspirations of the clients. Besides that, our team coordin
Technical Drying Services
Plot No 2274/3, Rajiv Nagar, Shiv Vihar, Behind Birla White Cement Godown, Bus Stand Road, Gurgaon, Haryana - 122001, India
Service Tax Return Preparation Service
As part of our Indirect Taxes Services, we offer credible Service Tax Return Preparation Service which covers major aspects related to preparation of documents and other material for filing of service tax returns. Some of the major points of our service are listed below : Procedure : Every assessee shall submit a half yearly return in From 'ST-3' or 'ST-3A', as the case may be, along with a copy of the Form T
Aggarwal Varun & Co
Plot No. 390, Near Rishi Public School, Sector-31, Haryana - 122001, India
Deals in accounts maintenance services, Trademark Registration Services, Company Registration Services, return filing services
Accounts & Finance Solutions
570/9, Subhash Nagar, Haryana - 122001, India
Deals in payroll accounting services, hr consulting, account outsourcing services, fipb approvals, Registration Services, Statutory Compliances Services
Amitabh Verma & Co.
294/1, Adarsh Nagar, New Railway Road, Haryana - 122001, India
Deals in Custom Clearance Services, licence services, tax registration services, company bank account services, owning state services, Company Registration Services, Company Registration Services, federal services, company registration sevices, Custom Clearance Services
Yuup.inc (from You To Us)
T-1/1405 Suhant Estate, Haryana - 122002, India