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Re: Experimental Fail
.....Look, I understand there's sort of a huge controversy surrounding ramyb's designs. I'm not saying the following because of that. I would say this no matter who the artist was, and I'm not trying to be nitpicky.
....but, I'm sorry, I just don't see the experiment here. Okay, you dumped chemicals on turtles in a terrarium and they... died? Umm, duh? When was the scientific method involved here? This is still off-topic.
Re: The Prince Charming Theorem
This. Shirt. Must. Print.
Love it!
megsck wrote:hahahaha, you know what these reminded me of, do you remember those plants that danced and played music? i used to have one and i loved it. really like this drawing, different from your usual and i approve. =)
Thanks Meg! I'm not too encouraged to experiment with other styles when I get so few votes. I guess it's also possible the joke is a little complex? Like it takes more than a quick glance to figure it out? I don't know.
Re: The RYB color model
This shirt cracks me up!
I LOVE the crazy little girl..haha
Re: Green Symphony
This is adorable and I really like the placement.
Re: Into the Wild Blue Yonder
funny, I was working on a similar themed one, though I think I'll refrain now. If I might make a recommandation, I would sugest that you place the image on the other side of the shirt... Now it looks like it would shoot off of the shirt, but placing it on the other side(or reflecting it for this side) it'll draw the eye back onto the shirt.
Re: Sky in a Jar
Beautiful! I'd totally wear it. :D
bassanimation wrote:Should have made it a bottle of Surge soda. Do they even still make that stuff? Holy cow it would mess me up...and it was that funky, unnatural green...-shudder-
we drank that all the time in school when it came out. not sure why they thought it was a good idea to stock the vending machines with it. surge was like an early version of energy drinks.
Re: fresh!
I really like the muted color choices. Nice job!
I think the shirt is attractive and well drawn, but I disagree with your portrayal of the mento. If the rules state no anthropomorphic animals, then doesn't the spirit of the law say no anthropomorphic candies? I don't know. Not trying to be mean, just thinking out loud (so to speak).
gryphoncreation wrote:funny, I was working on a similar themed one, though I think I'll refrain now. If I might make a recommandation, I would sugest that you place the image on the other side of the shirt... Now it looks like it would shoot off of the shirt, but placing it on the other side(or reflecting it for this side) it'll draw the eye back onto the shirt.
I actually had it on the other side of the shirt first, but then I kind of wanted it to look like it was shooting off into the sky and off the shirt. My plan worked! :D You should sub your shirt too.
Those frogs are so cute! Great concept and lovely colors.
wordwitch wrote:Not to be a raincloud on this cute parade, but no video games is one of the rules and this seems to be a Mario reference...
I immediately thought Little Shop of Horrors. Mario didn't even cross my mind until somebody else mentioned it and I really don't think this plant looks like the one in Mario. Very original and creative design, kevlar. gmv!
Re: How I know my cat is evil? by Billy Pugsmith III
taking the true spirit of the theme I have drawn a diagram as though done by a middle school child on the topic of his cat being evil as his submission to the science fair.
heartflux wrote:This made me laugh out loud... until I realized the unfortunate placement. "Dude, what's that on your boob?! You've got, like, angry snot in a dish on your left breast!"
Woot seems to place women's Ts slightly higher and slightly smaller to avoid booby decoration. Also, the collar on the templates comes down extremely far compared to a real shirt. I think this design would be fine if printed.
Great work truffle!
Re: Just Add Love (Version 2)
YAY! Excellent!
Re: My Pet Turtle Weighs 6 Balloons
best science project EVER!
Re: Pulley Overkill
I'm happy with this one.
5 colors on olive.
Re: Science Class
That is beautiful, and I have voted for it. I'm a little worried that it might be viewed as slightly off-topic and get rejected, but I hope it doesn't.
spazzysoph wrote:not to be a spoil-sport but hasn't this been done before?
thanks for pointing it out...I hadn't seen that when I did this...which is a bit of a bummer for me. having something similar takes away from both i think, i'm a hitchhiker, and not familiar with the older stuff. I hope to come up with other stuff too...
oh my gosh! For a second I thought the girl was yellow-red color blind! And then I realized that the second yellow bird was in a BLENDER! lol
neeznoodle wrote:Harsh!
Just playful. No malice intended.
I would SO buy this if it gets produced!It looks sort of like my cat after a bad day.
Meet Jimmy. He's the kinda dork you can really throw your lunch at. The kinda dork that takes pride in his science fair entry and doesn't care when the rest of the class laughs behind his scrawny back. In 10 years or so, when he creates the next big thing I just hope he remembers that I was never THAT mean to him...maybe he'll invite me to dinner, offer me a job, and when hes not looking...Ill throw my lunch at his rich, scrawny back!
Re: nerd pride!
Re: The Blue Ribbon Formula... At Last!
Up late, the night before the big science fair. The perfect mixture of chemicals were created... Poof! The honorable and sought after blue ribbon formula!
I hope everyone enjoys the design this week!
Special thanks to my model; Parker age 4.
Re: Calculator Fun
Kids love spelling words with calculators, so this is my take on that idea.
Re: You are here
Rat love! Since I have joined Woot, I have been very uninspired by most shirt designs... this one truly delights me! Votes!!!
taternuggets wrote:Just playful. No malice intended.
No worries. I knew that...
Love the fluidity of the piece and color choice. (And that you knew what a satellite looks like ^,^)
Can't stop laughing... I would love to add this to my "twisted childhood" selection of shirts that also includes the delightfully disturbing Peter Rabbit Revenge tee
Re: extinction theory
At least 3 miniature creatures are decimated by flying d20s every time I play D&D... this is the most realistic shirt in the whole derby ;)
neeznoodle wrote:Kids love spelling words with calculators, so this is my take on that idea.
Oh, hey there! It seems like you may have missed seeing the derby description and rules?
Here. Here they are for you.
In case you don't know, the derby description and rules are posted every Thursday in the main world of woot shirts forum. Therein you'll find the description and the rules for the contents and composition of your entry.
Awesome. I support this shirt.
I can't tell if some of these negative post against this entry are actually serious or just haters of ramyB. Either way, they're grasping at straws.
For example, the people arguing that an 11 year old would be smart enough to know this experiment wouldn't work. If you wanted the derby entries to realistically capture the experiments in a middle school science fair, we'd only have a bunch of entries revolving around potato catapults and posters based on the water cycle, which I'm pretty sure no one wants.
thewayisshut wrote:
....but, I'm sorry, I just don't see the experiment here. Okay, you dumped chemicals on turtles in a terrarium and they... died? Umm, duh? When was the scientific method involved here? This is still off-topic.
Ask a question:
Will turtles mutate and fight crime if exposed to a toxic substance?
Watched 16 hours of TMNT
Cartoons have never let me down before. Yes turtles will mutate.
Test Hypothesis:
Pour Toxins on turtles. Wait.
Analyze data:
Turtles have not grown, nor begun talking. Seem to be oblivious to ninja weapon supplied.
Turtles have died.
First place ribbon please!
Re: solid hypothesis
Not sure I would wear this. But it made my laugh.
Ah screw it, Ill wear it. gmv
lunadust12 wrote:we drank that all the time in school when it came out. not sure why they thought it was a good idea to stock the vending machines with it. surge was like an early version of energy drinks.
For awhile, when I called a friend and they answered the phone, I would yell "Surge!!!!!" Those were such weird commercials...
Re: Minor Modifications
I like the idea of this, I just wish the planets/sun were in order... that's a deal breaker for me
Re: Volcanoes Galore
Having turned in a volcano to a science fair, I find this hilarious. gmv
chumpmagic wrote: Blah
I think ever detergent I have used has been blue. Is there really a "glowing" green detergent. I would use it
I don't know about laundry detergent...but there's green dish soap...
View All →


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Why in the heck are homes so much in Australia?? I was looking at some home prices and couldn't believe it!!! Any city I chose was like San Francisco prices. Heck, a tiny home in Perth went for over a million US dollars. Crazy.How do you guys afford it? Honey must be selling for a LOT of money in order to pay those prices.Ken
This post was not meant to start a pissing contest between AU and the US.
Pom is like Australians=Aussie, Americans=Yanks, British=PomsIts an affectionate term... :)
Quote from: c10250 on February 04, 2010, 08:55:18 AMThis post was not meant to start a pissing contest between AU and the US.EXACTLY... When did this become "My Country is better than yours" post - please knock it off. Thank you all.Any way, we all have great countries, count your blessings and thank your God for that and carry on - TY.

subset: commoncrawl


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|Topic Review (Newest First)
The heat riser can be blocked off if your weather is always warm, unless you have a hot air choke. The hot air choke for a Quadrajet has a hollow tube that slips down into the riser passage, so I'm sure you know whether you have one.
There may be gasket sets with complete block-off plates, but I've always heard of folks just cutting the plate out of an old tin can.
Edelbrock Intake Manifold Install
Fel-Pro1204 intake gaskets have the solid plates that block the exhaust passage. Do a google search on fel1204. It might come up as FelPro Q1204. I know the Summit Racing website has a picture of the gaskets. If you decide to use the exhaust passage to heat the intake be sure to use a heat shield under the carburetor (EDE 9265)
Follow-up on "exhaust crossover"
A few clarification questions:
1. I've read that the "heat riser" ports are NOT really needed in fair weather states such as N. California, but then there are some that say they are recommended for daily drivers regardless of weather?
2. Are the holes in the "heat riser" metal plates designed to just partially
block the heat coming into the intake?
3. If I decide to keep the "heat riser" ports blocked, do I just keep them covered with the gasket? In other words, don't punch out the center gasket holes, or is there another set of metal plates that don't have a hole in them and block the heat completely?
The back water passages where never used.
Water is pumped down the sides of the engine, then it goes up into the heads and returns to the radiator through the front two passages passing through the thermostat. Do not worry about the pack passages.
One very important item to watch out for is that you put the correct length bolts into the heads. Some of the bolts line-up with some of the push rods. If you put a long bolt in there it will bend the push rod and the engine will NOT run smoothly. Just something to watch for.
Also if you are keeping the EGR valve then do not plug the cross-over passage.
Follow-up Comment
- Make sure you get the right gaskets for the intake, either Edelbrock or Fel-Pro. It isn't hard to find the right ones, but Edelbrock emphasizes that there are some other types out there that do not seal well with an aluminum intake.
- The blocking plates have interlocking tabs and there should be 4 pieces. You put one side of the plate in from each side of the gasket and then bend the tabs to hold it in place.
- Just use spray tack-a-gasket to hold the entire gasket on the head and don't worry about sealing the plates to the gasket.
- Use a 1/4" tall bead of oil resistant silicone to seal the ends of the manifold to the block. Do not try to use the rubber end pieces if you got them with the gasket set.
- For the water ports you may want to use a very small bead of silicone sealer to supplement the blue bead that is already on the intake manifold side of the gasket.
- All of the inner bolts (8 of them?) go through the head flange and into the oil gallery. When you install those bolts you should use some oil resistant silicone sealer on the bolt threads. If you don't, oil will wick up the threads and you will get oil residue around each bolt head.
- On my engine I've found that its much easier to install the intake if you take off the valve covers first. My valve covers have fairly wide flanges that get in the way when you drop the manifold in place.
- Make sure you have the manifold lined up on top of the gasket, and then hand twist all of the bolts into the head. Look carefully again at the manifold and make sure it is even from left to right. Then start with the torque sequence in the Edelbrock instructions.
- It is hard to get a torque wrench onto the center bolts because they are close to the carburetor pad.
Follow-up Question(s)
In using the metal plates for the center "exhaust crossover ports" for heating intake under carb", how are the metal tabs installed?
These plates are flat on one side, and have 2 tabs that rise at 12 & 6 o'clock at the center of the holes in the metal plate.
Do the tabs go down or up into the heads?
Are they placed on top or below the gasket?
Do the tabs need any sealant/rtv, or just lay them down?
Edelbrock Intake Manifold Install
Look at your intake carefully. The first passages on both sides of the front of the intake is the water passages. The center passage is an exhaust crossover. This heats up the intake for cold weather climate. If you live where there are mild temperatures you can block it off with the metal provided with the gaskets. Check out Fel-Pro 1204 intake gaskets. Looking at the pictures it looks as if someone tried to plug the rear ports of the heads. Also the center exhaust cross-over looks as if it was plugged. This wasn't necessary. You install the gasket with a thin layer of sealer around the water ports front and back. Some gaskets provide the metal to block the crossover or the metal will have holes so it can be used. If you don't use the metal the exhaust will eat thru the gasket and leak.
Edelbrock Intake Manifold Install
Make: Chevrolet
Model: Impala SS
Year: 1964
Engine: 327 cui
This is my first attempt at swapping out a intake manifold and I need a little direction.
Problem: Old Edelbrock intake (12 years) cracked.
Attempting to replace intake manifold with new Edelbrock intake manifold model 27013.
-When removing the old intake, the first thing I noticed was that the old intake has 6 water passages (the new intake has 4).
-The previous owner, for whatever reason, blocked the 2 end passages (near firewall) with some sort of cement filler within the intake itself.
Someone advised me that my heads were "camel hump", is there a difference between a "stock" intake and "camel hump" as far as the number of water passages (6 versus 4).
-The previous owner also did NOT remove the gasket center holes for the
middle 2 water passages, thus it appears the old intake was only circulating coolant via 2 passages (back 2 blocked, middle 2 gasket blocked).
In comparing the old intake with the new, the new one has 4 coolant passages (the back 2 were machined closed by Edelbrock), I'm guessing that was either for performance improvement or stock versus camel hump head configuration.
Also, Edelbrock included 4 thin metal plates with the new intake, how are those used and do I need to use them? Note: The new intake gasket has cutouts for the 2 center passages, you can't see them in the pic.
So, is it okay to go forward with new intake install after clean-up of heads/ports and suggested configuration?
Note: See attached pics of intakes, gaskets, heads, engine, etc.
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he's welcome to take what he can carry and go IF he thinks he'll get a better deal
Once, when I was about 12, my mother told me I was imprudent. When I got the dictionary, I mistakenly went to impudent.
and....he gets his moneys worth....
I like to hear his side of the story.


text:
Hi, I've just recieved and started putting together a resin Webley bought from Sidewinder, but I hve a few questions about the painting of it:
1. Are the stock and grip wooden?
2. If they are what's the easiest way to paint in a grain effect?
3. What scope should i try to get?
4. what scope mount should I get to fit it on with?
5. Is the gun Silver / black weathered or Gunmetal and weathered?
thanks y'all.


text:
I'm working and living in Philadelphia now so as much as I love this car, I've gotta let her go and start saving for a house. I've babied her since I purchased her, all recommended maintenance and only synthetic oil. It's completely stock except for a Kartboy shortshifter and bushings I had professionally installed.
Quick specs: 2009 Silver Hatch WRX with 45k miles. Stock except for Kartboy shortshifter with bushings, never touched the ecu.
Here's the Auto Trader Ad: Cars for Sale: 2009 Subaru Impreza WRX Hatchback in Philadelphia, PA 19147: Hatchback Details - 358866520 - AutoTrader.com
I'm asking for $19k, possibly negotiable.


text:
Latest News & Features More news »
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text:
Historically, over the past 150 years, the labor union movement emerged as a means of enabling industrial workers to band together in an effort to match the power of management. Germany once had powerful trade unions, but there is an increasing trend for the unions to fragment into smaller entities and fight for the rights of a group rather than band together in solidarity with the mass of workers. Mini-organizations representing specialized employees are making strikes more frequent and more complex in resolving organizational disputes. Germany's Lufthansa has ground workers in one group, attendants in another, pilots in still another segmented organization and no coherence between any of these entities. The result is turmoil for management and ineffectiveness in gaining organizational goals.
The splintering of labor representation is more harmful in fields such as the retail trade where management can readily find scabs to do the work of those on strike. The essence of historical labor unions was having people from a variety of jobs come together in a single union so management could not split them apart. When one entity went on strike all went with them which made for difficulty on the part of management to brush off demands. Ironically, as fragmentation proceeds, unions are becoming more aggressive and Germany is witnessing more strikes. The real issue is whether strikers are obtaining their goals.


text: I should be receiving my ASOK budget helmet today or tomorrow. From what I have seen and read it is a wonderful piece that doesn't deserve a amateur paint job. I might take on the challenge however if there is a Dallas area artist that has worked on it before and the price is fair I might look into hiring them. Please give me any names or leads you may have. Thank you!


text:
'"Teppo was released from the Cleveland Clinic on Tuesday evening and is now resting comfortable at home," said Hartich concerning Numminen's heart surgery last Thursday. "His post-operative recovery continues to be excellent and Teppo's right on schedule for a full recovery. His spirits are great and he's getting stronger everyday."'
Numminen released from hospital
September 27, 2007 Submitted by
Via: Sabres.com


text:
Click for "Microbes After Hours" videos
Richard writes:
Hi Vincent,
Just listened to this weeks twiv, and the q dot dyes you mentioned are also used in electronics. There they are used as a ultra precise phosphor. In that application blue light from LEDs can be re-emitted as red, and green. This gives an ultra precise RGB light source, allowing highly accurate colour rendition on LED backlit TVs.
It's surprising how often these crossover applications crop up. Another good reason to listen to twiv. This should happen more and more, as the technology singularity approaches.
Thanks as always for the interesting podcast.
P.s. no replies regarding magnetotactic bacteria. Though there's time yet. If not then I might have to experiment. I'm guessing replication of near anaerobic conditions, and elevated CO2, with the correct nutrients (nitrates, nitrides?)
P.p.s Best coffee maker? Airobe airopress, simple but highly effective.
Andrew writes:
Hi TWiV!
I've been listening to the show for a long time and I love it. It is great while I am working in the lab doing my plaque assays. Keep up the great work.
I just wanted to say I second Matt's suggestion from episode 175 to Tessa about the program Papers for organizing references and PDFs. In the new version you can also use it to cite while you right (kind of like EndNote). I know Tessa wanted an online version, but personally I love papers. It makes managing references really easy and it lets you highlight and take notes on articles you've read. If you are student you can get a pretty good discount, and they have great customer service.
Neil writes:
Dear Vince, Rich, Alan, and Dick (or V-RAD),
I just listened to TWiV 171. I believe it was Dick who said something along the lines of "wouldn't it be cool if you could label single virions and watch them in real time" (my paraphrasing, hope I got it right). I wonder what the other people at the gym thought when I blurted "it's been done!" (or did I just think it?!) Anyway I'm pretty sure this has been done for HIV by Tom Hope (Northwestern University) and more viruses by others. Here are some links to related information:
-images and movies from the Zhuang lab at Harvard: http://zhuang.harvard.edu/virus.html
-review article by Dr. Hope: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209483/pdf/nihms175435.pdf
-a related blog post: http://scienceblogs.com/purepedantry/2009/03/watch_hiv_t-cell_transfer_live.php
Anyway I think the technology is definitely out there!
Keep the great podcasts coming, I learn so much from them!
David Esteban writes:
Dear TWiV folks
This week, one of the founding editors of the Journal of Virology, Lloyd Kozloff, passed away. His daughter, a professor of Film here at Vassar College, notified me of his death. Although his name may not be familiar to many, he began his career at a very exciting time as a member of a group of phage biologists associated with Cold Spring Harbor, that included many more familiar names like James Watson and Max Delbruk. I can only imagine how thrilling it must have been for a young biologist to work at such an important time in the history of virology and molecular biology.
I wrote a brief blog post, with links to some of his early papers. Since you have discussed some historical papers on TWiV recently, I thought some listeners might be interested in seeing these as well. JVI will be publishing a more extensive obituary.
Brenna writes:
Dearest TWiV Doctors;
How would you approach current, and future, problems of being "research snubbed"?
About two years ago I was asked to help on a project with another lab. I was struggling to get my own research off the ground, so I had some time. I showed the post-doc how to do plaque assays, but it was obvious he was more inclined to let me do them. So we completed three experiments before my own research had to take priority over helping him. When things had calmed down I contacted to post doc about resuming the studies, but he never contacted me again. At the last experiment I got the impression that they had a new hypothesis about the experiment, and were eager to test it.
A few months ago I see that they have published a paper on that work. Now, no ethics were breeched. They never mention my work (although, to be fair my work likely gave rise to the studies actually shown in the paper), so there is no ethical issue. Just a matter of pride, time, and supplies that were used during their initial studies.
I was talking to a peer and she said that being "research snubbed" was the reason she required everything in writing prior to working with another lab group.
Is that what science has come to? There must be a contractual agreement to protect work and/or ideas? It worries me, because I love talking and sharing ideas. However, I have already come across one professor "borrowing" (stealing) my ideas for a grant, being research snubbed, and hearing stories of a researcher stealing ideas from a grant (and obviously scoring the grant low so it wouldn't get funded) and later publishing the research. And I don't even have a PhD yet!
What is a young scientist to do?
Long time listener, first time writer;
Tina writes:
I wonder if you are aware of the most recent study of MS and EBV. Whereas EBV has been a trigger suspect for MS since the 1980s, this new study shows that even if the virus is not actively replicating in the brain cells of MS patients, it is releasing chemicals that cause an immune system response.
I have a cousin with MS. I remember years ago finding out that MS is more common in subtropics compared to other areas. Some studies show it is important where you lived in your childhood and teenage years, as to whether you are at risk, no matter where you lived your adult years.
This and other studies prompted the theory that MS is caused by or triggered by a virus. A study in 2006 showed MS patients have an immune system overreaction to EBV. A 2009 study showed, after accessing 7 million blood samples, that those who had no infection of EBV did not get MS.
I find this very interesting as I am an ME/CFS patient. And MS has many similarities to ME/CFS. They both have post-exertional malaise or fatigue, much more pronounced in ME/CFS though. They both occur more in women. They both have a relapsing / remitting course for most patients. And they both have occurred in outbreaks. Lesions on the brain can also occur in ME/CFS patients, which – along with the similarity of symptoms – causes some with ME/CFS to be misdiagnosed with MS. (The lesions of ME/CFS are pinpoint, small white spots, but MS lesions are oblong.)
Ironically, ME/CFS has also been linked with EBV, even originally called "chronic Epstein-Barr virus syndrome." Some have noticed increased EBV and other herpes virus titers in ME/CFS patients.
It is well established that many, not all, ME/CFS patients develop the disease after a case of mono, such that a study is onging, following people with mononucleosis to see who develops ME/CFS and possibly why.
EBV hides in B cells, which is why the drug Rituximab is sometimes used off-label in MS treatments. And, in October, a phase II double blind study in Norway found Rituximab, which kills B cells, brings moderate improvement to 2/3rds of ME/CFS patients. A few have seemingly been cured. Those physicians theorize that ME/CFS is autoimmune in the brain. Some others have theorized that killing B cells may reduce ME/CFS symptoms because EBV hides there and could possibly be causing a malfunction in the B cells, causing it to make autoantibodies. Kill the B cells and you kill EBV.
Could EBV behavior inside the cells be the cause of two autoimmune diseases, depending on what part of the central nervous system is being attacked by autoantibodies?
I would love to hear your thoughts on all of this. Ronald Glaser, PhD, has done studies on CFS, and the effect stress has on EBV. Might this be the thing that brings together those who see ME/CFS is triggered by stress and those who think it is triggered or caused by a virus?
Greg writes:
Hi guys,
Great podcast! I'm a PhD student at McGill and I work on HIV, but in more of a biochemical context than a virological one. Your podcast is great at rounding out my knowledge of the virus I work on, and of course many other viruses as well. I'm sure this paper is on your radar, as it comes out of David Baltimore's lab, but I think gene therapy is an amazing technology and this seems like the perfect application in order to "cure" a difficult virus, HIV. (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature10660.html)
Nature. 2011 Nov 30. doi: 10.1038/nature10660. [Epub ahead of print]
Antibody-based protection against HIV infection by vectored immunoprophylaxis.
Balazs AB, Chen J, Hong CM, Rao DS, Yang L, Baltimore D.
John writes:
Dear TWIVvers,
I loved your Concerto in B episode (TWIV 161). Your discussion left me with a bunch of questions regarding B cells and antibodies.
As I was listening to the discussion of affinity maturation, I kept trying to think of how this process interacts with existing memory B cells, and in particular, how it interacts with original antigenic sin.
What happens when you already have a good population of memory B cells to an antigen. Do you get new germinal centers forming and the affinity maturation process going on again? And if so, does it start with the B cells that have already been through that process, or does it start with new, immature B cells that responded to the soluble antigen? Does that depend on how much new antigen is available (if you have an effective antibody response, does that keep this process from restarting?)
Do some mutations in the affinity maturation process close off the possibility of mutating back in some way that would be helpful later, or is all the raw material still around in a functional B cell after affinity maturation, so that you can get from a good antibody to the 2005 flu strain to a good antibody for the one you get in 2007? It seems like there must be some impact of the existing stock of memory B cells on future affinity maturation, or you wouldn't observe original antigenic sin. (And it seems like it should work the same way when there's antibody dependent entry of cells, as with dengue--is this right?)
Is this process the reason why some vaccines require three shots to get protection? (I recall getting the Hep B vaccine many years ago in three doses--the second shot a month after the first, the third six months later.). Or is this more a matter of getting enough antibodies, rather than getting higher affinity antibodies?
Finally, listening to the description of the germinal centers, it seems like they should run out of antigen, since they're using it up each time a B cell tries to take up and present antigen to the T cells. Is there some mechanism to recycle the antigen? Is the supply of antigen the limiting factor in this process, or is there plenty--maybe my intuitions at this scale are just all wrong?
Anyway, thanks for your wonderful podcasts, and for answering my amateur immunology questions.
Gabriel Victora answers:
Hi Vince,
Please congratulate you listener, these are all excellent questions. Unfortunately, I don't think we know nearly as much about these things as we should. Vaccine development has historically been mostly empirical, and regimes are usually based on what works best rather than on immunological considerations (most vaccines were actually developed by microbiologists). Part of the difficulty in addressing these issues is technical - it would be very difficult and costly to serially determine the affinities and specificities of B cells responding to antigen during consecutive immunizations of the same individual (or animal).
I've written some ideas about what might be going on below each question.
Hope this helps,
What happens when you already have a good population of memory B cells to an antigen. Do you get new germinal centers forming and the affinity maturation process going on again? And if so, does it start with the B cells that have already been through that process, or does it start with new, immature B cells that responded to the soluble antigen? Does that depend on how much new antigen is available (if you have an effective antibody response, does that keep this process from restarting?)
>> The original antigenic sin phenomenon is most likely related to the rapid elimination of antigen by existing antibody or by antibody produced soon after the second challenge by existing memory cells. The novel (ignored) determinant would not be capable of priming naive B cells because it would be bound by circulating antibody and complement and eliminated before it ever had a chance to do so. As to new GCs, emerging data suggests that some memory cells (those that haven't switched their antibody isotype) can make it back into GCs upon second exposure. I would expect that a secondary GC would therefore contain a mixture of B cells derived from naive and memory precursors. Many factors could influence the composition of this putative mixture, including competition between B cell clones for limiting amounts of antigen or T cell help.
Do some mutations in the affinity maturation process close off the possibility of mutating back in some way that would be helpful later, or is all the raw material still around in a functional B cell after affinity maturation, so that you can get from a good antibody to the 2005 flu strain to a good antibody for the one you get in 2007? It seems like there must be some impact of the existing stock of memory B cells on future affinity maturation, or you wouldn't observe original antigenic sin. (And it seems like it should work the same way when there's antibody dependent entry of cells, as with dengue--is this right?)
>> I think this is mostly a matter of the extent to which the existing memory cells recognize the newcomer variant. If it is enough to trigger an "original antigenic sin"-type phenomenon you would probably not generate new germinal centers, in which case you would get no further affinity maturation. However, naive B cells are constantly being turned over (dying and being re-generated in the bone marrow). Therefore, the likelihood of a "hole" in the repertoire in 2007 arising due to all flu-specific B cells having gone the 2005 way is negligible. But theoretically it is possible that an unswitched 2005 memory cell could re-enter a GC in response to 2007 viruses, and in this case, it is conceivable that some cells could be impaired by 2005-specific mutations, but these would be unlikely to last in the highly competitive environment of the GC.
Is this process the reason why some vaccines require three shots to get protection? (I recall getting the Hep B vaccine many years ago in three doses--the second shot a month after the first, the third six months later.). Or is this more a matter of getting enough antibodies, rather than getting higher affinity antibodies?
>> The three shots of vaccine have probably more to do with attaining high titers of circulating antibody in blood than with improving affinity. Serum antibody affinity already increases quite dramatically (up to 10,000 fold) within the first immunization, although serum antibody titers (a composite measure of affinity and amount of antibody) only really really go sky high after one or two booster shots. The idea is that whereas the first contact with antigen generates germinal centers and affinity-matured memory cells, the booster doses "reap the profits" of this germinal center reaction by triggering the ensuing memory cells to proliferate vigorously and differentiate into large numbers of antibody secreting cells within a few days. What the role in vaccination is of GCs emerging during booster doses is not clear (at least as far as I know), but could conceivably involve the recycling of unswitched memory B cells back into GCs for further affinity maturation.
Finally, listening to the description of the germinal centers, it seems like they should run out of antigen, since they're using it up each time a B cell tries to take up and present antigen to the T cells. Is there some mechanism to recycle the antigen? Is the supply of antigen the limiting factor in this process, or is there plenty--maybe my intuitions at this scale are just all wrong?
>> This is a good question. Antigen appears not to be limiting, since it can be detected on FDCs many months after the GC reaction has faded, though how available this antigen is at this point is not clear. Many hypothesis exist for why the GC response ends; these include competition between B cells and circulating antibody (which would sequester the antigen available on FDCs) and exhaustion of GC T cells (perhaps through their regulation by GC-resident regulatory T cell populations). I tend to favor the latter, but this is still a topic of fervent investigation.
John writes:
Attached are my two questions. I found your podcast even before the death of my sister during the 2009 H1N1 pandemic of '09. She died 14 Oct 09 from bilateral pneumonia as a result from a confirmed case of H1N1.
I received both the seasonal and H1N1 vaccines, as I'm not stupid, and not influenced by celebrities or former playboy bunnies (Ref. jenny mccarthy – Name intentionally lower case out of disrespect). I prefer my medical advice from a doctor, imagine that!
I'm sure I'll have more questions as I make it through the episodes.
Very respectfully yours,
Raihan writes:
Hello ...insert cool way of addressing you guys....,
In one of your previous twivs you guys mentioned about how after the H1N1 pandemic, the prevalence of Flu infections dropped, suggesting a 'boost' in herd immunity.
If you don't mind I would like to chirp in to this discussion.
I am a grad student studying influenza here in Singapore. In my confirmation presentation (which was at the end of the H1N1 scare),I presented the following chart taken from the Ministry of Health (Singapore)'s website.
The pink bar (pandemic H1N1) shows a decrease in size over time, corresponding to the end of the pandemic.
But what is interesting is that while pandemic H1N1 dwindles down, the incidences of seasonal flu A strains and flu B increases.
I am curious as to whether or not the same trend is observed in the US. You guys seem to suggest that after the pandemic the incidences of seasonal flu and flu B were not as prevalent, this is obvioulsy not the case here in Singapore.
On a separate yet related topic, I have to express my dismay in your podcast for not highlighting other types of Influenza. When you guys talk about flu, you exclusively talk abt flu A. This frustrates me as I am studying influenza B. I have only noticed influenza B Being mentioned only aBout 2-3 times in the course of your podcast, and it was always in passing. The only discussion aBt flu B was By Peter Palese where he suggested that flu B could be potentially eradicated due to its lack of an animal reservoir.
Pls dont get me wrong, guys are doing a Brilliant joB with the podcast, But flu B is my BaBy, would love to hear your insights aBt flu B as well.
My take aBout the 'Are viruses alive or not?' deBate;
I've Been thinking aBt this for quite some time and I totally agree that this is not exactly a biological proBlem as much as it is a philosophical one. As early as I can rememBer amongst the first few things taught in Biology is that the cell is the Basic unit of life. I think this is quite an agreed upon definition and no one would disagree with it, most of us would see this in Biology textBooks in all levels. Therefore since viruses are not classified as cells, it would Be impossiBle to define them as alive as much as organelles are not alive.
Hope my email did not Bore or Bother you guys. Just take my earlier complaint aBout Flu B as the rantings of a PhD student trying to come in terms with his lack of publishaBle data.
Marcie writes:
Dear TWIVers,
I am listening to episode 164 "Six Steps Forward, Four Back" and as you were mentioning the fact that you wished you could reach everyone it occurred to me that the podcast title, This Week in Virology is a little intimidating to people who may only have a high school knowledge of science. I am not suggesting that you change the name of the main show, but maybe you could do an occasional single-topic, explain--it-to-the-layman show when there are hot topics like the HPV vaccine, the H1N1 spread, or the H5N1 publication controversy. These could be the short ~15 minute shows that target a broader audience than your regular shows. The name would need to be something general, so as to cast a wide net (all of microbiology/immunology--you certainly have sufficient connections that you can recruit experts to do bacterial or fungal topics) if not broader ;-). It would also need to be non-threatening to the average person (think "Idiot's guide to...") so it would need to avoid words like Virology and Microbiology. Maybe something like "Hot Topics in Health and Disease."
Pittsburgh, PA
Where it is currently 50 degress F, and overcast.
Sven-Urban writes:
Ave, magi virorum!
(That ought to put me pretty high on the list of creative/obscure greetings!)
I have just enjoyed episode 169, where You all discussed the question from Sophie on how to read scientific papers. I fully enjoyed and appreciated Your learned views, all of them very valid for You as scientists. However, not all readers of scientific papers need be or become scientists, so perhaps You might let me add one layman's perspective.
Just to give You the general picture, I am a Software Quality professional with a 30 year old M.Sc. in computer science. Out of general curiosity and for personal entertainment I occasionally read science papers from other disciplines, mainly from the section Evolutionary Biology in PlosONE. Many of the intricate details in those papers, whether they be on primatology, paleontology, ecology or (particularly) biochemistry, are usually beyond my grasp and knowledge. That's fair, scientific papers aren't written for laymen, and Alan's way of describing a paper as a highly compressed packet of information for transmission over distance was very instructive. What I look for, and hope to find, is something reasonably digestible at the "beginning" and "end". As Dickson pointed out the pictures and graphs are very important, as they may aid, or sometimes hinder if badly designed, the intuitive understanding of the data, and here too good handiwork might aid my understanding. With well worked out introductions, discussions and illustrations I, the layman, should be able to grasp the general problem/question/hypothesis, as well as the general result/conclusion/implications. And that's my main point, on some level a scientific paper ought to be accessible also to the non-initiated – if it's not, the paper and science is in some sense poorly or obscurely presented. (On the other hand, if science papers were always graspable by the populace Alan would be out of business pretty soon...) Of course, as a layman not understanding the details I have no way of assessing the validity of the results presented, but that is of less concern as I am not using the information gleaned for anything else than maintaining my image as an "incurable intellectual" around the coffee pot at work!
Searching my bookshelves for a listener pick-of-the-week I found something that at least distantly tags in with the main theme of the episode. I suggest two highly accessible books on how we tend to overly rely on noisy, possibly meaningless, data, how we tend to extrapolate trends ad infinitum and how we can not disprove the odd/unknown/unobserved phenomenon: "Fooled by Randomness" and "The Black Swan", both by Nassim Nicholas Taleb.
Thanks for Your continuing effort!
P.S. The greeting supposedly means "Hail Ye, mages of viruses"; kudos to Internet if I'm right, shame on me if I'm wrong...
Colm writes:
I have been listening for a while and finally have enough disjointed comments to merit hitting send, I hope.
First, you frequently make references to temperature conversion. Born and raised in the United States, I have a poor understanding of Celsius as it relates to real life. I know my incubators are at 37, and that's toasty, and the lab is in the low 20s and that's "Room Temperature." I wonder if yo know of a weather application for iOS or Android that displays C and F side by side, for building those associations. I think it would be an amazing feature.
Secondly, I am not a Redditor, but I was recently made aware of their 'Ask Me Anything' threads where experts/insiders field questions from the community in long-running dedicated threads. For example, George Pelecanos, a writer and producer for The Wire and Treme recently answered dozens of questions in such a thread. It would undeniably be a massive time sink, but may be a useful way to disseminate Virology to the public.
Third, and finally, you mentioned in this week's epidemiology TWiV that BSL-4 facilities seem to be predominantly government run affairs. That is generally true, but I am aware of at least one privately operated US BSL-4 in San Antonio at the Texas Biomedical Research Institute. The More You Know.
Diane writes:
Because I have CFS, I learned about you and your various podcasts during all the XMRV hoopla. After many years of struggling, I have been able to teach part time for several years now. I teach biology at a junior college, both a majors and a non-majors course, and I thought you would appreciate something that happened early on this semester.
I always start my classes with what I call "bioliteracy topics." I will briefly introduce something in the news that is both interesting (I hope) and usually controversial. So of course I chose as one topic the H5N1 controversy. At the time, my understanding was that the mortality rate was near 60%.
Meanwhile, I had decided to listen to all the current TWIVS, TWIPS, and TWIMS, and to slowly go back and listen to all of the old episodes. So of course you know that I had to correct myself with my students the very next class! It actually helped me to make a point that I love to make – that science is not merely a collection of facts to memorize, it is a process. Those who undertake science must maneuver through this process, and the public needs to understand that, at any given time, the information they have may not be the final word, and in fact, what they are hearing in the media may be misleading or simply incorrect.
I allow my students to earn some bonus points by responding to the bioliteracy topics on exam days and several chose to write about the H5N1 controversy. I'm pleased I was able to provide them with information beyond the headlines – thank you for that!!


text: for me, the decision came down to price. i went with 9mm because here in detroit walmart has them in 50 round boxes for $10.97 as opposed to $14.97 for the .40. now, i may be off here but i have a county sherriff that has shown be ballistics reports that indicate that the 9mm round and the .40 s&w round are almost.....almost identicle in every way. that is what swayed me. now, my wife just bought me a p250sc for my birthday and that one is also in 9mm just because it's easier to stock up on one caliber.


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Discussion in 'Other Hoops Talk' started by OLD SKOOL HQ, Sep 11, 2009.
Tell me your kidding.........
Like I said before, Teasley is the JR Rider of the WNBA. The best thing she does is make you appreciate Katie Smith more. Teasley has bounced around the league as much as Tameka Dixon. It just goes to show you that a mind is a terrible thing to waste.
Hold on Uncle OldSkool, Tameka had game when she first entered the league, but the more and more she began to look like a man, her game started to fade, that said, I'd still take her over Teasley!!!
That game was probably the most exciting game in the Palace this year. I forgot how satisfying it was to watch players really play their hearts out on the court. The hustle, the defensive lockdown, the storming of the paint. Awesome job ladies. Hornbuckle is a warrior. The block from behind on Catchings in the beginning of the 3rd quarter was fantastic. Zellous has room to grow, but she's been solid. Nolan seems to have a nuclear reactor in her core, the way she keeps going. I just wish that Braxton didn't dribble the ball every single friggin time she gets it down at the post. Sometimes you just catch and shoot dammit. Anyways, they sent a message to everybody with that game "we are still the champions, and we ain't giving away our title for free". I can't wait until the next game tonight.
The NBATV feed is a crappy local Indy radio broadcast. WTF is this madness??? Are there no unbiased commentators available like the last game? Is this what the WNBA has come to? I mean come on. It's a playoff game!
I know what you mean. Only 20 more minutes and the Fever are history.
Big comeback at the end of the 1st. Shock need to break them early in the second half. Fever are fragile right now.
God damn it Hornbuckle . Stop the turn over and make the open god damn lay up.
Home cooking now. Fever getting call after call.
no kidding, can you say "rig" ? First Hornbuckle missed a point blank lay up and now Ford. Can anyone make a point blank lay up on this team? And now no one can make a 3. The Shock must have took like 10 shots at the 3 point line in the last 2 minutes. Looks like there's going to be a game 3.
Still out on vacation in AZ, so I missed tonights game....in reviewing the box score it looks like Cathings was living at the FT line and our ladies committed to many TO's (24) which the Fever turned into 28 pts. yikes!! It's do or die for defending champs...does Mahorn dress his injured players on Sunday??
Dre they play Sat, it's a back to back. Seems like too many TO's and and the girls let the Fever live at the FT line. But if the ladies played that bad and only lost by 4, we should be able to take care of business. Win or Lose, these ladies have already shown incredible moxy!!!
I watched it. A heap of those 24 TOs were steals, mostly strips. I think Katie Douglas had 5 steals. Shock made some mistakes, but the TOs killed them. The Fever got the home cooking whistle, and that was no help because they turned the defensive intensity up early. Shock can win if they limit TOs and control tempo.
Nice article about a bad boy. http://www.nytimes.com/2009/09/26/sports/basketball/26mahorn.html?_r=1&ref=sports
GO SHOCKS! C'mon LADIES!
Christ! That's like the 6th screw-up for Braxton and it isn't halftime yet. Will the real Braxton show up soon? Make that 7th screw-up at 22th second. Can a coach make a player to change back into street cloth because she's not going to be playing after halftime?
Well we lost, most of the blame goes to Hornbuckle and Braxton for those damn turnovers. Both of them owns 99% of it. And also Katie Smith for being injured. Where is Bill Laimbeer when you need him. He could have made some good trades instead we got Teasley and Kelly. WTH Malhorn? Another disappointing basketball season in Detroit. Man we cannot catch a break.
I think it was a great season for the Shock. They missed two AllNBA players and still only lost to a hometown ref and we had to listen to a home call game. Our team deserved better! IF the WNBA folds, they deserve it until they start acting like a pro organization. The Fever only shot free throws the entire quarter. And their old woman coach shot down The Shock in her interview...Low class.
Lin Dunn to coach the Pistons? She would command more respect than MC. I guess I'll give Kuester a month. But if he isn't kicking some serious butt, then I'm going to start the Lin Dunn for coach movement.
Well I only saw the second half, and agree that the TO's was the one of the keys as to why Shock lost.....the Fever didn't win the game...the refs and Hornbuckle lost the game for the Shock... I saw three TO's by Hornbuckle in a 2 minute span in the 4th qtr. And that last loose ball foul called in the last minute where Sutton-Brown wasn't even touched was the clinching homer call to assure that Indiana got the W. Not sure how bad Katie's back was, but she should have been dressed and could have made better decisions down the stretch than both of our future stars in Zellous and Hornbuckle, even if she played just in the 4th qtr. Another incomplete season by a Detroit team, but you are right even with two superstars on the shelf, they still almost beat the Fever. Good job ladies!! Oh yeah, what did the fever coach say in the post game interview that was low class. I got up during the Holdsclaw/Kamler discussion and didn't see the trophy presentation.
Separate names with a comma.


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a place for zinesters - writers and readers
Hi! How long is there still time to submit the thing about social anxiety disorder?
Thanks so much for Hearts! A pocket-sized piece of art.
Yes, I'd love to!
Beverly Hills, CA 90212
Looking forward to it!
Got your zines in the mail yesterday... nice of you to throw in that extra of your brand new 1. Big Thanks.
Nope didn't get yours so please send whenever you can.
Hello, hope you are having a nice day when you get this. Welcome to the zinesters of color group! I plan on buying your zines pretty soon, they both sound great. Ordinarily I'd be up for a trade but all of my copies have been spoken for right now. Well, hope to hear from you soon.
Howdy C.A. Did you get my zine? Sent it like 3 weeks ago or so
We invite you to take part in the First International Exhibition "ZINESHOW" in Ukraine. Participation is free. Any technique. No return. Deadline: 15/04/2013. Exhibition on the blog http://zineshow.blogspot.com All works will be exhibited also in the gallery "Tymutopiyapres" http://tymutopiyapres.blogspot.com is not a commercial gallery. Desired summary of your zine or about you or your creative work (this is necessary for further elucidation of the project and possible documentation). Zines for the exhibition please send air mail: "Zineshow" A/C 9875, Sadivnycha 19/1, 79038, Lviv, Ukraine. mailposht[.]gmail[.]com
it looks great ..lets trade ..I have seen your beautiful art before :)
Thanks for getting back to me. ...postcard #1 I am interested in. Are there copies left?
Howdy. I'm up for zine trade if you still have copies left.
Thanks so much for the zine, I enjoyed it very much. I like the idea of the rubber band to put things together...great idea. Thanks again.
I just make up your package and it will go out on Monday.
Jon Foster 707 Watson Ave.
Winston Salem NC 27103
If you'd be interested I'd trade you my China zine for your work? Let me know if you're interested.


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By Joe Brewin
Rachel Yankey believes Kelly Smith's return from injury will give Arsenal Ladies a huge boost ahead of a crucial run of Women's Super League fixtures - starting with Birmingham on Sunday.
The England striker rejoined the club alongside Alex Scott and Gemma Davison in March but has yet to feature after picking up an ankle injury on international duty.
Smith was an unused substitute for last week's 3-0 Continental Cup victory over Chelsea and Yankey expects her to be as strong as ever.
"It is a massive plus for us," the midfielder told Arsenal.com. "We signed Kelly, Alex [Scott] and Gemma [Davison] together and we were just unfortunate that Kelly was injured while away with England.
"She hasn't actually played a game for us yet so I think it will be a big boost. She has been with us back in training for the last week on a non-contact basis so hopefully when we come back from our England trip she will have had a few more sessions.
"But she looks really sharp and to be honest she doesn't look any different to how she used to. I think it will take her a while to get match fit but you can already see some of those technical qualities where you wouldn't even know anything has been wrong with her.
"We look forward to her coming back and strengthening the team."


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Audi Acquisition of Ducati Announcement Due Next Week Says Reuters Report
by, 04-11-2012 at 04:23 PM (12464 Views)
Though rumored for at least a month, Audi is poised to announce its acquisition of Italian motorcycle manufacturer Ducati says a Reuters report. Two unnamed Reuters sources described as "familiar with the matter" say Audi encountered no major stumbling blocks during performance of its due diligence, which suggests all systems are go.
The Reuters report seems to think the announcement could come on April 18, one day ahead of the Volkswagen annual shareholder meeting slated to happen in Hamburg, Germany. One source suggested that major Ducati shareholder, Investindustrial, would only talk with Audi regarding a buyout. The acquisition would move the Volkswagen Group portfolio to 12 brands - a target Ferdinand Piech has eyed for some time.
Timing is also consistent with the end of the Audi exclusive discussion period according to Italian newspaper Corriere della Sera, siting that period as ending on April 15. The newspaper also suggests that Audi tried to buy Ducati back in 2005, but that Investindustrial trumped the offer and picked up the motorcycle company from its then owner Texas Pacific Group.
Read more from this report via the link below.
Audi may announce Ducati buy next week: sources | Reuters.com


text:
|hope college > campus offices > cit
Cable TV
Cable TV is available through Hope College and Comcast for all residence areas at no additional cost to students living there. This includes all college-owned residence halls, cottages and apartments.
Residence Halls, Fried and Delta Phi Cottages
A direct cable connection is available in each individual room in the residence halls on Hope's campus. After connecting the power cord to your TV, connect the coax cable (available at the Hope Geneva Bookstore) to the outlet in the wall. Using your TV remote, run the auto program to be sure you are receiving all of the available channels.
A direct cable connection is also available in the common living areas of the Fried and Delta Phi cottages.
Cottages & Apartments
A Comcast DTA (Digital Transport Adaptor) is required for all CATV connections in Cottages and Apartments. Public locations (Living room/Lobbies) will have these installed and active. This adaptor includes a remote control that will be used to change the channels on the TV. Note: All Comcast channels are digitally encrypted and require this DTA to work correctly regardless of the age of the TV. TV's with QAM (Digital) tuners will not work without the DTA. Additional DTA's are provided free of charge through Comcast.
To connect:
All Hope College cable is provided by Comcast and the channel lineup is the same for the residents of the City of Holland. The current cable TV contract does not provide the College with a mechanism for offering upgraded services (HD, DVR's, OnDemand) to individual residence locations.
If you need additional support call the CIT Help Desk at x7670.
Hope College | Computing and Information Technology | 110 E. 10th St. | Holland, MI 49423


text:
This RP is based around a group of survivors who are abandoned on a island.
The GM (me) will periodically throw in events, etc to keep players busy, and to possibly shift things up.
No meta gaming. To prevent such, I would like for everyone to create their persona with 3 traits, one 1 influence.
Here are a few example of traits, they should fall into 3 categories, physical, mental, and spiritual. Spiritual traits are luck based, and the GM will decide accordingly if it's to be carried out. For the sake of creativity I will let you create your own.
Here are examples however.
Enduring: Able to carry out physical activities for extended periods. Not very susceptible to minor or mild poisons.
book worm: retained large portions of information. Possibly valuable.
Faith: Prayers can possibly heal.
Influences are, for the most part, what you did in life prior to being stranded.
So basically, if you've never built a house, or dipped into being a architect, or possess survival knowledge, then that means in no way can you suddenly build a hut for everyone.
I will begin
Chase 'Sosa' Ramirez
Age: 20
Fast learner: Easily learns new things, visually and orally.
Deep thinker: Master of critical thought. Can think out well orchestrated plans and motives.
Enduring: Able to carry out physical activities for extended periods. Not very susceptible to minor or mild poisons.
Influence: Hardware; because last job revolved around hardware, this individual has a large amounts of prior knowledge regarding tools and gadgets.
My character will essentially be able to craft tools, but I know Jack about cooking..etc, see where I'm going?
When enough people have joined we can get this going altogether, if it's a successful rp I can elect others to be GM.


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Administer programs, raise funds, and direct organizations
Veterans, service members and their spouses are eligible to receive a 10-15% military tuition discount.
Tuition discounts from Capella-affiliated employers and colleges can help make your degree more affordable, potentially saving you thousands.
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See what it's like to take a Capella course with a one-week, free trial course.
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Estimate Your Costs and Graduation Date
Evaluate tuition, discounts, and transfer credits to calculate your costs and graduation date.
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Test your readiness to see if you're prepared for a successful online learning experience.
Both the government and nonprofit sectors need public administration professionals to lead and evaluate strategic initiatives, assess public needs, administer resources, and more. Gain these skills and many more through a flexible, online public administration program from Capella.
Your Capella education will prepare you to be a valuable collaborator and advocate. Through a competency-based MPA, DPA, or certificate program, you'll be able to implement what you are learning right away and make an immediate impact on your career and your community.
Administer programs, raise funds, and direct organizations
Conduct research, work in government agencies, and develop policy
Manage public resources and work to develop policy and processes
Capella's streamlined curriculum provides maximum efficiency and cost savings while ensuring that you develop skills aligned to your professional goals.
Capella is a member of the Network of Schools of Public Policy, Affairs, and Administration (NASPAA)—a global standard in public service education—ensuring your degree is highly recognized and respected in the public administration field. Capella's public administration programs are designed around national public administration curriculum standards, including those from the NASPAA.
Capella is a proud partner of the YMCA, providing employees with a flexible format to advance their education and further improve the communities they serve. We have aligned our competencies within the nonprofit management and leadership doctoral and master's degree programs to match what nonprofit employers, such as the YMCA, are seeking.
Investing in a college degree is no small thing. At Capella, we're proud to share our learning and career outcomes—along with gainful employment results—so that you can make the most informed decisions about the programs that interest you.
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With Capella's Inspire Giving program, you don't have to wait until you graduate to make a difference. Every time you share your stories or connect Capella with your community we'll make a charitable donation to the nonprofit of your choice.


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Off-grid community The Citadel Project gets thumbs up to manufacture firearms
guns.com / By Max Slowik / February 6, 2013
A company called III Arms has just received ATF approval to manufacture firearms. Setting up a gun manufacturer is just a small part of III Arms plan, which is to establish a completely self-sufficient community in the mountains of Idaho.
It will be called The Citadel and include a walled urban center10 feet thick by 20 feet high and four miles longsurrounded by rural plots for farming. It is, to turn a phrase, a planned prepper community.
Despite being armed and armored, the Citadel isnt being made to defend its people from military or government action, rather, its intended to be a safe haven for forward-thinkers to weather a social, economic or environmental collapse. It is at the leading edge of anti-establishment living, but it is not designed to withstand any direct .mil or .gov attack. Nor is the Citadel, in any manner, attempting to provoke any government entity, according to the project FAQ.
III Arms began taking pre-orders for AR-15 rifles and 1911 handguns last November anticipating the FFL. Both have pre-order prices of $1,550, reflecting the difficulty of making small batches of firearms and current market trends. Theyre also limited by the availability of certain parts, although it stands to reason that down the road theyll be able to make everything in-house, should everything else go according to plan. All profits, if any, will go towards expanding their manufacturing capabilities.
On III Armss blog, project founder Jim Miller wrote, In this afternoons mail, III Arms Company received a little note from the ATF saying: Thanks for your interest, please start building firearms.
READ MORE: Off-grid community 'The Citadel Project' gets 07FFL
Black Blade: Cool! But I have my own "Citadel" much further south and I have plenty arms and ammo for myself and my people.


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The Entrepreneurial Business Award is Back Again
September 12, 2012
Wittenberg, OH
During the fall semester, Chase Beach, Zachary Cole, Trev Hughes and Melissa Sullivan will be working as WittConsultants for the 2013 Entrepreneurial Business Awards (EBA Award). Over the next three months, the team will work on promoting the award through, social media, advertising, and other public relation activities. Their main job is to manage the nomination process, receiving nominations of Clark and Champaign County businesses that have an innovative business approach that has proven to be successful. After collecting and analyzing information on each business, they will narrow the selection to five finalists.
Meet your WittCAM Consultants:
Chase Beach '15 is a sophomore Business Administration major with a focus in Entrepreneurship from Cincinnati, Ohio. At Wittenberg, he is involved with WittInvest, the Student Athlete Academic Counsel, and participates on the mens varsity lacrosse team. Back home Chase is actively involved with his church and volunteers with the junior high kids club. His future aspirations include starting up his own business geared towards using renewable resources in everyday life.
Zach Cole '15 is a sophomore Business Marketing major from Florissant, Missouri. He currently works with the Wittenberg Police & Security department, the Delta Gamma Housing Corporation, and has also served as a tutor through the America Reads program at the Salvation Army. Cole is an active member of Beta Theta Pi, serving as philanthropy chair while also participating in planning Greek Weekend and other campus involvement events. In addition he writes for Wittenberg's school newspaper, The Torch. He is part of the East Asian Business Fellowship and studied abroad in Shanghai at Fudan University in the summer of 2012, immersing himself in the culture and language while taking marketing classes as well. In the future, Cole aims to work for an international marketing firm.
Trev Hughes ' 15, is a sophomore Business and Entrepreneurship major from Boulder, Colorado. He has interned at Earth Balance working on development of the annual marketing plan. At Wittenberg, Hughes is head of Phi Gamma Delta marketing, apparel, and website. He has been appointed to work on the Phi Gamma Delta social community to plan and organize its philanthropy event. His future aspirations including working in marketing for a Natural food organization and ultimately starting his own natural food company.
Melissa Sullivan '14 is a junior Business major with a concentration in marketing from Sarasota, Florida. In Sarasota, she worked retail sales at Garden Argosy, a locally owned gift shop and boutique located in the heart of the bustling St. Armand's Circle. In 2011, Sullivan traveled on a mission trip to Tegucigalpa, Honduras and participated in efforts to beautify a local orphanage and agriculture school. In 2010, she interned for Bailey & Bailey Law firm where she gain knowledge about the complexity of law and shadowed an attorney during numerous court sessions. Sullivan plans to pursue an MBA after graduating from Wittenberg University and then is interested in a career in integrated communications.
Wittenberg Center for Applied Management (WittCAM): The Wittenberg Center for Applied Management, better known as WittCAM, offers alternative coursework to upper-level students who are focused in management. As an alternative to a classroom-based course, WittCAM provides students with the opportunity to serve as consultants to businesses, government agencies and not-for-profit organizations. Students and organizations have a choice of opportunities, including: Small Business Institute, Project Management Assistance, Management Internship, and the Creative Advertising Partnership. Students may work in groups or as individuals on projects. Some projects require specific management course prerequisites; these vary depending on the nature of the project. More than 500 students have been involved in WittCAM projects in the last 35 years. Director, Professor Wendy Gradwohl, PhD; project coaches: Professors Pamela Schindler, Tim Bode, and Tom Kaplan.


text:
When frosting has been cleaned from tired little faces and sugar-charged playmates have been sent on their way, what remains at your house or party place is this: a small mountain of disposable paper products galore, from streamers and plates to pinatas and pizza boxes, all destined for the trash after one-time use. Before you give in to the birthday carbon footprint stomp, read on.
Red Tricycle shows you how to plan an eco-friendly party, from invitations to party favors. With a few simple, inexpensive tweaks, you can turn your kiddo's moment in the sun into a definitively green day.
For starters, choose reusable decor and party wares, which may be enjoyed year after year instead of crumpled up and tossed at the end of the festivities.
Green Planet Parties makes it easy to ditch the paper varieties of decorations with their gorgeous selection of felt banners and garlands, table cloths and runners, felt tabletop confetti, and even a high chair bunting and bib set. Instead of a typical cardboard cone party hat, make your kid king or queen for the day with a personalized wool felt crown from Chloe in Style, which may also double as a keepsake. If you're pressed for time, fret not, you can still deck the halls with last-minute green decor by using your printer. Paper and Cake printable party ware, from cup sleeves to cupcake picks is downright darling. Just be sure to use recycled paper and ink, and recycle or reuse this party decor.
Read the full list of eco-friendly party ideas at Red Tricycle.
Once a week we post content from our partners at Red Tricycle, an excellent online resource for busy parents looking for fun activities to enjoy with their kids.


text:
In re S.J.L. and J.K.L.
Our Sponsors
Rita Goodman and her former partner, Siobhan LaPiana, were in a committed relationship for 10 years. During that time, the couple had two children. LaPiana gave birth to the children but both women parented the boys equally. The women drafted and signed a parenting agreement before the birth of their first child, detailing their intent to share all responsibilities of parenthood. After the couple split up, LaPiana began restricting Goodman's interaction with her children. Goodman went to court and a Cleveland trial court ordered shared custody of the boys for Goodman and LaPiana. LaPiana appealed, arguing that Ohio's antigay constitutional amendment prevents courts from ordering shared custody to lesbian former partners and that the court's order infringed on her right to autonomy as a parent. Lambda Legal represented Rita Goodman. We successfully argued that Ohio's antigay constitutional amendment has no impact on Ohio courts' authority to order shared custody between former same-sex partners. Additionally, the appeals court agreed with us that because LaPiana agreed to co-parent her children from birth, it is constitutional for courts to step in to protect the children's bonded relationship to their second parent.
- February 2007 Rita Goodman files her application for custody.
- March 2007 Siobhan LaPiana moves to dismiss her application, arguing, among other things, that shared custody between lesbian former partners would violate the Ohio constitution and her right to parental autonomy.
- July 2007 The trial court denies LaPiana's motion.
- June 2008 A hearing takes place at which many witnesses testify that LaPiana and Goodman planned their family together, and that the boys consider both of them to be mothers.
- August 2008 The trial court orders shared custody and LaPiana appeals.
- November 2008 LaPiana files appellate brief.
- January 2009 Goodman files appellate brief supported by friend-of-the-court briefs from the National Center for Lesbian Rights, the National Association of Social Workers and the NASW Ohio Chapter, and the Ohio Chapter of the American Academy of Matrimonial Lawyers. The guardian ad litem for the children also files a brief in support of affirming the trial court's order for shared custody.
- January 2010 Oral argument of the appeal is held.
- August 2010 Victory! The Court of Appeals affirms the trial court's decision and rejects LaPiana's claim that she was entitled to sever the children's relationship with Goodman. LaPiana does not attempt to appeal.
Case Information
Rita Goodman
Lambda Legal
Camilla Taylor
Co-counsel/Cooperating Attorneys
Pamela J. MacAdams of Morganstern, MacAdams & DeVito Co., LPA, in Cleveland, Ohio.


text:
|Topic Review (Newest First)
And it's not good for you to be breathing in the epoxy dust either. I wet sand everything but the filler. It just seems to cut faster.
I use spray bottles and it keeps the surface wet, and not puddle up on the shop floor as much as running a water hose.
One thing I like about wet sanding is being able to see the work so clearly. Using a rubber squeegee like the one shown. You squeegee the water off and wham, you can see every detail. They make them in different sizes. And they work as a little "block" as well.
3M Rubber squeegee
|Irelands child
Why I wet sand
First of all I am aware that a lot of you do your sanding dry and do a great job so I can't knock it. As a proclaimed amateur having fun (most of the time, anyhow) find that wet sanding works best for me for several reasons:
1.The sand paper lasts longer without clogging - my estimate is 3 to 4X as long and the Scottish side of me is happy (did I say that I'm leaving for Scotland next week for 2 weeks for reindoctrination and few wee drams of uisce beatha)
2. The wet surface keeps the sanded-off substrate from building up under the paper so you don't end up sanding with the dust
3. The constant flow of fresh water keeps the rest of the surface reasonably clean and shop dust down to a minimum.
While I can't always use a dribbling hose on the many separate pieces such as from this '31A, I am using it on the body proper. A modern integral fendered car, using a hose is easy.
There are a couple of downfalls to this:
1.Your hands get nice and soft and wrinkled (your significant other might appreciate this though ) then cut easily if not careful.
2.You are usually standing in a puddle of water, and depending on the time of year, might be uncomfortable, especially if you are using a dribbling hose
3.Any buckets of water need to be changed out regularly and dumping it into the yard or driveway is messy. A small shot of Dawn dish soap in the fresh water makes the water "stick" better and provides a sheeting/clearing action on the panel.
One caution - if you do drop the wet sandpaper on the ground, throw it away or as a minimum rinse it off anywhere but in the bucket. I picked up one grain of dirt and made 2 long scratches in my fresh poly primer before the brain kicked in and said stop(did I say that wet sanding tends to be brainless ). They weren't that deep but could have been.
Now - back to softening my hands again
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Arsenal train ahead of Villa match - Pictures
Arsenal's first-team squad went through their final preparations for Wednesday's Barclays Premier League match with Aston Villa when they gathered at London Colney on Tuesday.
Arsène Wenger took the training session and our official Club photographer sent back these exclusive pictures.
To buy official Arsenal pictures visit Arsenal Pics Arsenal Pics
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Aston Villa v Arsenal
Van Persie - The secret to my success
Captain on key factors behind his Club record-equalling run


text:
Let vs. Where
From HaskellWiki
This seems to be only a matter of taste in the sense of "Declaration vs. expression_style", however there is more about it.It is important to know that
that is, it can be written whereever expressions are allowed.In contrast to that,
like the pattern matching line of a function definition.
1 Advantages of let
Consider you have the function
f :: s -> (a,s) f x = y where y = ... x ...
However, transforming to
f :: State s a f = State $ \x -> y where y = ... x ...
f :: s -> (a,s) f x = let y = ... x ... in y
This is easily transformed to:
f :: State s a f = State $ \x -> let y = ... x ... in y
2 Advantages of where
Because "where" blocks are bound to a syntactic construct, they can be used to share bindings between parts of a function that are not syntactically expressions. For example:
f x | cond1 x = a | cond2 x = g a | otherwise = f (h x a) where a = w x
in order to represent the guards:
f x = let a = w x in select (f (h x a)) [(cond1 x, a), (cond2 x, g a)]
Without such a function it looks worse. You would lose the guard structure, and the heavier lexemes arguably make the resulting function harder to read:
f x = let a = w x in if cond1 x then a else if cond2 x then g a else f (h x a)
3 Lambda Lifting
One other approach to consider is that let or where can often be implemented using lambda lifting and let floating, incurring at least the cost of introducing a new name. The above example:
f x | cond1 x = a | cond2 x = g a | otherwise = f (h x a) where a = w x
could be implemented as:
f x = f' (w x) x f' a x | cond1 x = a | cond2 x = g a | otherwise = f (h x a)
The auxilliary definition can either be a top-level binding, or included in f using let or where.


text: Mothers have basic needs unique to their stage of life. Help mothers in your women's ministry recognize their needs and see that each one can be ultimately satisfied by Christ:1. Significance: "Sometimes I wonder if mothering matters."Moms need to know their role has value and makes a difference in the lives of their children. But ultimately, they need to realize that their work as a mom … [Read more...]


text: So two days ago I was watering my plants when this came in , she had some scratches so I gave her some water, then went to grab my keys to take her to the vet but by the time I was back she had dissapeared. So right now (really five minutes ago!) I´m in my bedroom and who comes through the door? Allie (yes she has a name). What should I do? I´ve never had a cat, I know next to nothing about cats in fact I have a dog... I don´t know if she´s somebody´s pet or if she is lost. Should I make her a bed? What kind of food should I give her... please any advice?


text:
sc,Glad you got it worked out. :)I like your label a lot! I recognized the palmetto and the crescent as a SC thing from my Tigers playing the gamecocks! :-D
You mean that other University in SC. The real University of SC is Clemson University. Oh by the way the real TIGERS also :-D


text:
Posted by Holger Kisker on December 5, 2011
Some Reflections On The Deal For Competitors, Partners, and Customers
The Deal
On December 3, SAP announced the acquisition of SuccessFactors, a leading vendor for human capital management (HCM) cloud solutions. SAP will pay $3.5 billion (a 52% premium over the Dec 2 closing price) out of its full battle chest and take a $1 billion loan. SuccessFactors brings about 1,500 employees, more than 3,500 customers, and about 15 million users to the table. In 2010, the company reported revenues of $206 million and a net loss of $12.5 million. A price of $3.5 billion is certainly a big premium, but the acquisition catapults SAP into the ranks of leading software-as-a-service (SaaS) solution providers — a business that will grow from $21.3 billion in 2011 to $78.4 billion by 2015 (for more information, check out our report "Sizing The Cloud"). The deal will certainly help SAP to achieve its 2015 target of $20 billion revenue and 1 billion users as it mainly targets the 500,000 employees that SAP's already existing customers have. The deal is expected to close in Q1 next year. However, because most of the stocks are widely spread, stakeholders might hold back for now, waiting for possible counter bids from competition.
The Organization


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Follow Harriet on Twitter
About Harriet
- The Poetry Foundation's blog for poetry and related news.
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Posts Tagged 'acrostic'
lost poets and found poetry in washington, d.c. November 24, 2009: (Photo Credit: Thomas Sayers Ellis) I'm good at getting lost. A few years ago, living in a French town so small even its residents had barely heard of it, I lost my way at least once a week. I was [...]


text:
|General Technical Chat This section is for technical discussions relating to general maintenance, electrical issues, engine trouble, and recalls.
|Topic Review (Newest First)
Help me or shoot me...hesitation above 1200 RPM
2001 Ford Focus ZX3, S2, 2.0 Dual overhead cam
My issue started about 2 weeks ago. I was on my way home from work, ran into the gas station for some milk, and when I get in the car to start it it just cranked for several seconds before it finally started up. No issues for a week after this. Then last Tuesday on my home from work when I would pass a vehicle on the highway and it would start to surge and hesitate. I ended up missing my exit and had to do some city driving (about 30mph) the rest of the way home. While going 25-30mph up hill, it felt as though my car was falling on it's face. Once it got level I was going smooth again. So I pulled it in the garage and checked for DTC and fuel trim.
What I found at the time was no DTC's but fuel trim was at +24(lean). I monitored the vehicle's engine data saw that my rear 02 sensor wasn't giving me any reading. So I swapped my fuel pressure relay(per another forum post), replaced the 02 sensor, PCV, ignition coil connector (wires were damaged where they went into the connector), DPFE sensor (because of posts I saw on the forums), fuel filter and drained the tank got a few gallons from the gas station (in case it was bad fuel). After replacement , my rear 02 now gives me a reading, I have the same fuel trim reading(+24), and my fuel pressure is reading the same (30-35psi on my pressure gauge, 36-40 on the scan tool through the sensor). I continued checking for external vacuum leaks - none found. I did replace the tube behind the intake (connects to PCV, the tube really soft) and the tube from the valve cover to intake (just to change).
Also, before I forget, I did test drive it after replacing the first set of components (prior to changing the vacuum lines) and it drove like crap. Anything about 1200rpm it feels/sounds like the converter is clogged or I have a huge exhaust leak near the engine where it would suck in air through the exhaust.
So, I disconnected (and damaged) the egr tubing at the exhaust side and put my blow gun to it. Under light throttle/pressure with the blow gun I can hear it leaking into the intake. So, I deleted the egr to retest. Fuel trim numbers are now perfect at idle, they fluctuate between -2 and +4. So I think, ha I fixed it.....WRONG. I lower the car and pull it out of garage and I can feel that same severe hesitation on light acceleration (anywhere above 1200RPM) and fuel trim when it is running rough is again in the 20's (lean). So I pull the car back on the lift, apply a rod to the brakes (for light to moderate brake pressure), and put the car in gear. The car accelerates smoothly (up to around 2500rpm) and is going at about 60mph. I checked for exhaust back pressure, at idle it bounces pretty good but is in spec on the gauge. I increase the rpm and it stays right at 0 the hole time (makes me think cat isn't clogged). But at the dealer we would just disconnect the cat and take it for a run, so I did the same. Popped the cat loose after the flex and pulled it out - no difference, in the driveway or going down the street anywhere near or above 1200RPM it falls flat on it's face. After letting the vehicle idle in the driveway for about 2 hours I did have a history P1233 and yes I have searched forums and the web for that code and have ran as many tests that I came across related to that code.
By this time I have already checked plugs (look normal), checked for spark (all cylinders look the same), TP sensor operation and MAF sensor operation (using scan tool), checked injectors for operation at different rpm (using stethescope), checked injector operation doing a balance test (all injectors drop from about 45-46psi to 15-17psi), I checked compression (I'm at or above 150 on all cylinders), and checked plug wires for resistance ( I have the livewire plugs) the all read between 250-550ohm depending on length (you can see some arcing points where the plug wires over lay each other). Checked my original factory plug wires for resistance they are all between 2.5kohm-5.5kohm.
I swapped out the screamin' demon coil pack and my aftermarket wires with the vehicles original - no change. By this time I also redrained the tank, and pulled the pump (I saw the posts about the fuel pump extended warranty, which mine expired a year ago). I already have the new redesigned pump, but the strainer/pump sock looks like crap. So they don't just sell the stainer kit, so I bought a new NAPA fuel pump and retested - NO CHANGE...
Now, we are about up to date. This last part was done last night and my brother was here to rev it up in gear for me while it was on the lift and I am starting to get it to fail there as well (hearing the occasional back fire as well). Clearly I don't expect anyone to be able to fix it through the forum for me, but clearly there is something I am missing or forgetting to check and that is where all of you come into play. Below is a list of some other things that I recall testing and then below that is a list of the mods that have been done and resent repairs.
IAC: spec is 6-14 ohms (I'm getting 10.7 ohms)
Injectors: spec is 13.7-15.2 ohms (I'm getting 17.2/17.1/17.2/17.2 and I'm getting .1 across my leads, so average at injectors is right at 17ohms)
Injector Balance: 45-46 peak, dropping to 15-17 on all for
Compression: about 150-153 on all 4
TP: Normal flucation with voltage/percentage as the pedal is depressed (much like myself at this point)
MAF: normal fluctuation with throttle change
Plug Wires/Aftermarket: 250ohm-550ohm depending on length
Factory Wires: 2.5kohm-5.5kohm depending on length
Fuel pressure on my gauge/new pump:
Key on Engine off: 45psi
Running: 30-35psi
Fuel Pressure old pump:
Key on Engine off: 40psi
Running: 30-35
Fuel Pressure with scan tool:
Running: 40psi - average
STFT at idle: Near 0
LTFT at idle: Near 0
LTFT on throttle/when hesitation is present: above 20 (lean)
FPDM testing:
Battery Supply/Key on Engine off: 12V
Battery Leaving/Key on Engine off: 12V
Signal Voltage w/ key on engine off: Fluctuating between .3-8v
Parts Changed for this Issue:
Removed tune from vehicle and reset to factory (I have since moved back to the tune since it made no change)
Fuel Filter
Injector Connector
Rear 02 Sensor
EGR Delete (fixed fuel trim levels at idle, but not drive-ability issue)
Fuel Pump
Plug Wires and Coil (swapped back to original/factory)
Recent Repair
Installed electric vacuum pump to brake booster and sealed off engine vacuum line (vacuum to booster was only at 15 psi and braking was weak, now vacuum to booster is near/at 20psi and I can lock up my brakes).
---I did disconnect the fuse to this pump in case the electrical draw causing this issue, but no change.
I did recently change the battery and removed my underdrive pulley and reinstalled the factory pulley - I did this because I am no longer on home dispatch and have to drive my vehicle about 31 miles each way to work.
New timing belt and tensioner about 1.5 years ago
Vehicle Mods
INJEN Inake (not cold air)
Crower Stage 1 Cams
Adjustable Cams
Livewire wire set/Screamin' Demon Coil Pack
OBX race head and MBRP 2.25" catback exhaust
--Modified exhaust to install cat (about 5 years ago)
SVT Brake Kit
SVT suspension
65mm TB
Anyway questions or info would help, right now I'm just grasping for anything. And for those of you who took the time to read through this book I've just written, THANK YOU...
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GameSpot Score
Final Fantasy XIV Online Review
Square Enix's laborious online role-playing game is a step backward for the genre.
The Good
Impressive visual engine Flexible class system lets you be what you want, when you want.
The Bad
Absolutely miserable interface Does a poor job of communicating important information Limited questing means you're always looking for something fun to do Everything about the economy stinks Every aspect of the game is filled with dumb obstacles.


text: The FBI has launched an investigation into the AT&T security breach first reported in Valleywag earlier this week. According to a report in the Wall Street Journal, the Federal Bureau of Investigation in the United States has begun to look into the circumstances surrounding the breach that left hundreds of thousands of iPad 3G owners exposed to potential attack. While … Read More


text: VMY185EMR-LAB Experience Homestay Culture Package Labuan TOUR INCLUDES• Return airport transfer• 2-night accommodation @ Host families• Meals as per itinerary• Tour and activitiesTOUR EXCLUDES•Return air ticket/ferry ticket•Items not mentioned aboveDay 1• Arrive in Labuan, transfer to homestay• Welcome drink & reception• Meet host family• Activities with hosted family and villagers such as virgin coconut oil processing - bukit kuda• Oyster Mushroom farming - bukit kuda• Playing top with villagers – bukit kuda• Dinner at local restaurant – Mawilla yacht club with 1 person homestay representativeDay 2• Breakfast with host family• Proceed for half day Labuan tour & duty-free Shopping• Lunch at local restaurant• Making 'Ambuyat' and traditional cakes (Kueh Punjung, Bahulu, Cincin) - Sg. Labu• Sunset view with Hi-tea- Sg.Labu• Farewell Dinner with host family/karaoke sessionDay 3• Breakfast with host family• Free at leisure• Depart to destination Contact Information HMD Tours & Travel Sdn. Bhd. Lot 3, Jalan Kemajuan, U234C, Bangunan Bay, Resort, P. O. Box 345, 87008 Federal Territory Labuan 087-416 117 / 087-417 117 087-453 884 email@example.com


text:
Plymouth man relates growing up in the home — the Sullivan County Home
By MEGHAN PIERCE
Union Leader Correspondent | June 17. 2013 7:06PM
Flowers were everywhere on the Sullivan County Home property in Unity center, Mike Ahern says, when sharing this old family photo of his two oldest sisters and his oldest brother. (COURTESY)
When his parents retired in 1984, the couple was replaced with three people who then separately ran the county farm, jail and nursing home, Ahern said.
His retired parents returned to their farm in Plymouth, where today Ahern owns and runs Glove Hollow Christmas Tree Farm.
"My dad was an incredible man; he was part of that greatest generation," Ahern said.
"Listening to the tapes ... there were just some amazing stories about the jail and the county home," he said.
"It was the neatest trip. My kids had a blast," he said.
Before searching the woods, they walked the grounds. His old family home was no longer there, but he found another building on the property that had been named after his parents.
In the nursing home he found the tunnel that went under the road from his house to the nursing home and walked it with his children till they found it had been cemented off halfway through.
His older sister Karen Arel, 61, of Kennebunk, Maine, though, said she remembers several instances of inmates getting away and of one time when a former inmate, who wanted to kill her father, came back with a gun looking for him.
"Every time there was a prison break my dad would take his revolver out of the locked file cabinet and take a look and my mother had us all praying. It was scary for us," Arel said. "I didn't remember the keys getting lost, but I remember how many times he went out and got them back to the jail. He went out a lot."
She could see her father talking four inmates out of the woods, by himself, she said, "He was very mild-mannered and calm."
"My mom used to say the world is made up of a lot of different people and you have to learn to get along with all of them," Arel said.
Her father didn't report the incident because that would have meant a state prison sentence for the inmate and her father didn't think the man was beyond redemption.
Arel said she got a great deal of work experience at the county home, working in almost every aspect of the home.
She went on to be a nursing home administrator in Goffstown.
* e-Edition subscription required


text:
Dolphin Artists :: Social Distortion
Related ArtistsMudhoney, Joe Strummer, Reverend Horton Heat, Brian Setzer, MxPx, Rancid, Pennywise, The Vandals, CKY, Rise Against
Social Distortion is an American punk rock band formed in 1978 in Fullerton, California. The band currently consists of vocalist and guitarist Mike Ness, guitarist Jonny Wickersham, bassist Brent Harding and drummer David Hidalgo, Jr. Social Distortion temporarily disbanded in 1985, due to frontman Ness' drug addiction and troubles with the law, which resulted in extended stints in various rehabilitation centers, that lasted for two years. However Read more on Last.fm more
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text:
TheTacticalTim is a decent one for reviews of conceal carry.
Hickok45 is probably my favorite right now, good thread idea, share the wealth
My personal favorites include:
The Armory Channel
If you haven't seen these guy's Youtube channels you should find some right now, very cool fun handgun guys
TheTacticalTim is a decent one for reviews of conceal carry.
Hickok45 is probably my favorite right now, good thread idea, share the wealth
Hickok45, wish I had his range, looks like fun.
Humans For Targets is OK and I do really enjoy Hickock's videos the most but I think the Military Arms Channel is a little more informative on some of the nuts and bolts.
The Armory Channel? Pete seems like a nice guy and all but some of his stuff is so full of fail it's laughable, but in all fairness I haven't seen any of his recent stuff so it may have gotten better.
The wife does youtube videos and we are thinking about trying to get her to Hickok's range after baby #2 arrives for her "Getting back into shooting" video. Oh to get on that range...
Someone look for faliaphotography
She has nice reviews. Very nice reviews.
P.S. Seriously, the review are thorough and visually pleasing!
Gotta be Limatunes. Smart, experienced, and what a BABE!
Hickok rules.Dude is awesome.I also get a kick out capt.Berz
Hickok45 for sure, and Nutnfancy has some good reviews also.
Hickok 45 & sootchOO!!!
What be "YOUTUBE" ?
I do have a 32 inch "mytube" in my mancave.
And I used to have "hertube" hanging around, but we got divorced.
Hickok 45 for me.
Hickok45 (I love how he always NEEDS to shoot just a few more times)
and now
Paul Gomez (thanks VAMarine!!)


text:
John Harrigan's Woods, Water & Wildlife: The origins of old terms, and the warriors at camp
June 29. 2013 10:59PM
"Locavore" is a trendy term these days, although I prefer "localvore." But whatever the case, there's nothing much more local than jump-steak, a code-word for venison. That's what we'll have if I have any left, which only rummaging around in the freezer will tell - plus any locally raised vegetables we can find, though for us it's early in the season.
John Harrigan's address: Box 39, Colebrook, NH 03576, or email@example.com
* e-Edition subscription required


text: Readdle has been developing some great apps for the iPhone and iPad in the business and productivity category. Their most popular app ReaddleDocs for iPhone is a must have app for managing documents on your device. The developers recently sent us a update about their latest app for iPhone and iPod touch called Calendars. The app is beautifully designed and … Read More