text:
Aurangzeb Haneef, MTS '09, has seen his home country of Pakistan transform into a target for criminal activity and terrorism. In response, he says that he's built up 'a certain numbness' toward acts of violence as a means of emotional survival.
When he heard of the double suicide bombing that killed 80 people at All Saints Church in the Pakistani city of Peshawar last September, however, he was shocked and deeply saddened.
"It was a new low," he says. "Two suicide attacks on a Christian church during Sunday mass. So many casualties. I felt disgust and grief."
If the violence of recent years has thickened Haneef's skin, it has also increased his desire to make a difference. That's why he works to encourage peace building from an Islamic perspective, both through the classes he teaches at Pakistan's Lahore University of Management Sciences (LUMS) and as an adviser to students.
"In my classes and talks, I promote critical understanding of Islamic religious tradition, religious peace building, and interfaith dialog," says Haneef, whose courses include "Islamic Studies,' 'Jihad: A Social, Political, and Theological History," and "Classical Sufism."
"I also run an online student discussion group where these and other topics are brought up."
The night after the church bombings, Haneef ran into a former student, Sarah Khan. A Muslim, Khan felt enraged and ashamed at the way the terrorists had used Islam to justify the attack. She says that Haneef shared her revulsion.
"Professor Haneef condemned the perpetrators of the attack outright," she says. "He said that the victimization of non-Muslim minorities in the name of religion is not only inhumane in itself, but also undermines the moral integrity of the Islamic religious tradition."
Soon after, Haneef joined the dean of the School of Humanities and Social Sciences at LUMS in a meeting with about 100 students who wanted to respond to the violence. Haneef offered himself as an adviser to any student initiative that would engage with religion for peace building.
"I highlighted the importance of involving religious people, students, and the LUMS Religious Society," he says.
A Collective Response to Violence
The following week the students organized a candlelight prayer vigil on campus in response to the attack on the church. As a result of discussions among the students, a new initiative called Aahang ('harmony') was started.
"Aahang strives to achieve greater tolerance, plurality, and inclusiveness in a culturally rich and colorful Pakistani society," Haneef says. "It also promotes dialogue and participation to solve outstanding issues and gain better knowledge of the 'other' including followers of religions or sects other than our own, or people belonging to an ethnicity or identity different from our own."
Haneef had been engaging both in person and via the Facebook group he started to "have more interactions with students on matters pertaining to Islam, peace, and conflict." When another faculty member told him of an upcoming demonstration of solidarity with parishioners at nearby St. Anthony's Church, Haneef shared the information on social media.
Khan joined the group sponsoring the event, Pakistan for All, and planned to attend. She says that to keep silent and do nothing would have made her an enabler of "religious fascism."
The solidarity event took place on Sunday, October 6, 2013, two weeks after the attack in Peshawar. Khan and some of her LUMS classmates joined hundreds of demonstrators—both Christian and Muslim—in a "human chain" around St. Anthony's Church in Lahore to protect parishioners from attack. The families of several of her classmates forbade them to participate due to fears of another attack, but Khan says there's no safe haven from religiously motivated violence.
"The extent of terrorism and violence in our society leads us to question whether we are really secure, even when we are in the comfort of our homes," she says. "Would you still pretend to focus on your daily chores when your house is on fire and a part of your family is being burnt alive?"
Haneef wanted to join the demonstrators, but did not. He had seen religious scholars killed or forced to flee the country for challenging extremist narratives. Moreover, to preserve his credibility as a scholar, he needed to appear "neutral...in an environment where polarity is increasingly the norm."
"I have to keep a low profile," he says. "I am more of a teacher now than I am an activist. In the sensitive and dangerous environment of Pakistan, it is necessary to quietly do your important work without attracting too much attention."
Mobilizing for Real Change
Still, Haneef did speak out, and publicly. In an editorial for the International New York Times's Express Tribune, he argued for religious solidarity, writing that, "When innocent Sunnis, Shias, Ahmadis and Christians, or anyone else for that matter, are victimized by self-righteous Muslims in the name of religion (or as collateral damage in the larger 'clash of civilizations'), this threatens the 'moral integrity' of the Islamic religious tradition."
Looking ahead, Haneef says he will continue his critical scholarship and campaign for interfaith and intrafaith harmony in Pakistan. He gives credit to HDS in these areas, and says that the School provided him with knowledge and multifaith experience that helps him to make a difference.
"Before coming to HDS," Haneef says, "I lacked the theoretical framework, the theological foundations, the academic rigor, the vocabulary, the deeper understanding of the Islamic tradition, and most importantly, the guidance of teachers to challenge and fine tune my thoughts. HDS provided me with all of this. Professor Diana Eck's course and her book Encountering God helped me approach important questions about 'us' and the 'other' in a profound manner. Interfaith prayers and multifaith community events were a great way of knowing the other and a source of inculcating respect for other religious traditions."
Haneef says that he hopes the students he teaches will, like Sarah Khan, become part of a movement that will someday bring peace to his country through a serious engagement with religion.
"Some religious organizations and political parties have condemned the church attacks, but haven't done anything concrete to change the ground realities," he says. "Unless they become mobilized, secular voices will have little or no tangible impact in a deeply religious and divided society of Pakistan."
—by Paul Massari


text:
Pittsburgh Symphony Orchestra debuts some new faces
More than fresh faces will be on display when two musicians make their Pittsburgh Symphony Orchestra debuts at concerts over the final weekend of January.
The debut of German violinist Christian Tetzlaff is particularly overdue.
Now 46, Tetzlaff actively pursues the full range of repertoire, not only from old to new, but also from concerti to chamber music, including string quartets and recitals. His programming shows keen musical intelligence, finding new perspectives with unusual juxtapositions of repertoire.
Michael Francis will conduct the Pittsburgh Symphony, with Christian Tetzlaff as violin soloist, at concerts Friday to Sunday at Heinz Hall, Downtown.
Francis, a young conductor who took up the baton while a member of the bass section of the London Symphony Orchestra, will open with Wolfgang Amadeus Mozart's Symphony No. 40 in G minor. After Tetzlaff plays Anton Dvorak's Violin Concerto, the concert will conclude with two colorful Slavic tone poems — "Sarka" from "Ma Vlast" (My Country) by Bedrich Smetana and "Taras Bulba" by Leos Janacek.
Tetzlaff comes to Pittsburgh at the end of a busy month in Europe during which he's performed Johannes Brahms' Violin Concerto, a mixed recital, Felix Mendelssohn's Violin Concerto and Brahms' three Violin Sonatas.
The violinist says he is the personal factor plotted against something big in nature in the Dvorak Concerto and that the piece begins with "a quite serious attitude, not devastatingly dark, in a proud, serious mood." The concerto's form is not unusual, with a slow-moving second movement he characterizes as a beautifully sung aria and a joyous finale.
"It's all about the language of the music, (Dvorak's) language and orchestration," says Tetzlaff. "The problematic part of the piece is that the violin writing is quite unusual, a bit more difficult than it sounds. We prefer it, usually, the other way around. But that doesn't mean it's not a great piece."
Tetzlaff's wide-ranging repertoire developed naturally, fed over time by curiosity.
"I sampled one composer after another when I was 12 or 13, when I was playing all the time in orchestras — (Anton) Bruckner and other things for young people, which are overwhelming, direct and easy to grasp in an emotional way," he says. "Later on, I got a strong liking for Mozart and (Franz) Schubert. At the same time, I was playing quite a lot of more contemporary music, such as starting with (Bela) Bartok and (Alban) Berg especially."
Tetzlaff makes it a point to perform a world premiere every year. He likes having connections with composers.
Yet, he notes that, statistically, his core repertoire is mainstream: Ludwig Beethoven leads with 250 performances followed by Johannes Brahms with 180 to 190.
"I like to play and then the best pieces appeal to me more and more. I've never, never had the feeling that playing them so often takes away," he says. "I get more confident and more in love with them when I play them."
Mark Kanny is classical music critic for Trib Total Media. He can be reached at 412-320-7877 or firstname.lastname@example.com.
You are solely responsible for your comments and by using TribLive.com you agree to our Terms of Service.
We moderate comments. Our goal is to provide substantive commentary for a general readership. By screening submissions, we provide a space where readers can share intelligent and informed commentary that enhances the quality of our news and information.
While most comments will be posted if they are on-topic and not abusive, moderating decisions are subjective. We will make them as carefully and consistently as we can. Because of the volume of reader comments, we cannot review individual moderation decisions with readers.
We value thoughtful comments representing a range of views that make their point quickly and politely. We make an effort to protect discussions from repeated comments either by the same reader or different readers
We follow the same standards for taste as the daily newspaper. A few things we won't tolerate: personal attacks, obscenity, vulgarity, profanity (including expletives and letters followed by dashes), commercial promotion, impersonations, incoherence, proselytizing and SHOUTING. Don't include URLs to Web sites.
We do not edit comments. They are either approved or deleted. We reserve the right to edit a comment that is quoted or excerpted in an article. In this case, we may fix spelling and punctuation.
We welcome strong opinions and criticism of our work, but we don't want comments to become bogged down with discussions of our policies and we will moderate accordingly.
We appreciate it when readers and people quoted in articles or blog posts point out errors of fact or emphasis and will investigate all assertions. But these suggestions should be sent via e-mail. To avoid distracting other readers, we won't publish comments that suggest a correction. Instead, corrections will be made in a blog post or in an article.

subset: commoncrawl


text:
Bartow PD Organizational Structure
The Bartow Police Department has evolved over the years from a one man, 15-hour-a-day department to a staff of 41 sworn and 26 non-sworn personnel who provide Law Enforcement services to the citizens of Bartow.
The officers assigned to the Uniform Patrol Division provide 24 hour a day coverage to protect the life and property of the citizens and visitors of Bartow. The Uniform Patrol Division acts as a first responder to calls for immediate police service providing a timely response to reported crimes in progress. The Patrol Unit consists of four squads, each squad is supervised by a Sergeant.
Sgt. O'Dell began his employment at Bartow Police Department in 1994. Prior to full-time employment, Sgt. O"Dell was a member of the Volunteer Reserve Unit from 1986 to 1993.
Sgt. O'Dell was assigned to the Patrol Division from 1994 to 1996. He was promoted to the K-9 Unit in 1996 where he worked with K-9 partner Turbo for several years. In 2003 Turbo went into retirement and Sgt. O'Dell was promoted to Sergeant.
Sgt. Hunt began his career with Bartow Police Department in 1991 after volunteering in the Bartow Reserve Unit from 1988-1991.
Sgt. Hunt played a major role in developing the K-9 Unit and served as a K-9 Handler from 1994-2002 with K-9 Nero. He was promoted to Sergeant in 2000.
Sgt. Hunt has been an instructor at Kenneth Thompson Institute of Public Safety Academy with Polk State College from 1994-present.
Sgt. Goff began his career at Bartow Police Department in 1995. He is a graduate of the Southern Police Institute Administrative Officers Course in Louisville, KY (2007). He holds a Bachelors Degree in Criminal Justice from St. Leo University and in 2014 received his Master of Science Degree in Criminal Justice.
Sgt. Goff attended FDLE Florida Leadership Academy and Institute of Police Technology Management's (IPTM) Managing the Patrol Function Course.
Sgt. Goff has served as Entry Team Commander and Field Training Officer Coordinator.
All felony cases are forwarded to the Detective Division where they are evaluated for solvability by the Detective Division Supervisor. If a case has a good chance of solvability, the case is assigned to a detective. Case solvability is determined by the existence of investigational leads. These leads must indicate the potential for successful arrest and conviction. Since police resources are limited, it is not effective or practical to devote investigational resources to cases with little chance of a successful resolution.
Detective Sergeant Eric Sherouse is currently assigned as Supervisor to the Detective Division. Sgt. Sherouse began his career with Bartow Police Department in April 1998, serving in the Patrol Unit for several years before transferring to the Detective Division. As a Child Crimes investigator, he and has over 12 years of investigations experience. He served in the Detective Bureau as a General Crimes Investigator and Narcotics Investigator, prior to being assigned to Child Abuse in 2007.
Detective Sergeant Sherouse received his police standards from Polk Community College in 1997. Since that time, he has received over 400 hours in advance training; primarily from the Institute of Police Training and Management, focusing on Criminal Investigations. Detective Sherouse holds a Bachelor's Degree in Criminal Justice and Sociology from Saint Leo University.
The Community Services Team is responsible for providing the citizens of Bartow with programs designed to enhance the quality of life as well as provide valuable services to the citizens of Bartow. The concept involves utilizing a multi-agency approach to problem solving by partnering with other agencies such as Code Enforcement, Fire Department, State Attorney's Office, Bartow Chamber of Commerce, and working with community groups to identify neighborhood and chronic crime or nuisance issues.
Sergeant Bryan Dorman is currently assigned as the Supervisor to the Community Services Team. Sgt. Dorman began his career with the Bartow Police Department in 1998, assigned to the Patrol Division. While in Patrol, Sgt. Dorman was a member of the Traffic Unit, investigating Traffic Homicide crashes. In 2006, Sgt. Dorman was promoted to Corporal. and assumed supervisory responsibilities of a patrol squad. Sgt. Dorman became a High Liability Police Instructor at the Kenneth C. Thompson Institute of Public Safety and continues to teach the same to officers In-House. In 2012, Sgt. Dorman was assigned the task of leading a new unit, the Community Services Team (CST). The CST continues to be a success.
Sgt. Dorman completed Police Standards at Polk Community College in 1998. Sgt. Dorman earned a Bachelor's Degree in Business and Criminal Justice from the University of South Florida, and a Master's Degree in Business Administration (MBA) and Criminal Justice Management. In addition to having attended numerous instructor and supervisory courses from a variety of educational institutions, Sgt. Dorman is a graduate of the Certified Public Manager Program through Florida State University.
There are three full-time officers assigned to the schools in Bartow.
The Bartow Police Department K-9 Unit is composed of four (4) teams, each consisting of a police officer and a canine. The K-9 teams are assigned to the Patrol Division. These teams assist the Patrol Division with searching buildings, searching for lost or missing persons, evidence recovery, narcotic searches, and crowd control. In addition, K-9 teams are utilized as backup officers for officer safety.
The K-9 teams are available to perform public K-9 demonstrations for the citizens of Bartow. The Community Services Division handles the scheduling of the demonstrations upon request from the public. Demonstrations are provided to schools, day-care centers, civic groups, community events, holiday events, business promotions and churches.
The K-9 teams average 25 to 35 demonstrations per year for the community.
Bartow PD Communications
The Telecommunications section of the Bartow Police Department falls under the auspices of the Support Services Division. In 2013, a major renovation of the telecommunications area was completed. The new space includes state of the art equipment.
Staffed by nine (9) full-time and two (2) part-time dispatchers. This section is responsible for radio communications as well as all NCIC and FCIC communications activity.
On January 25, 2016, Bartow Police Department implemented a new Report Writing Program called Tiburon. With the launch of Tiburon, Bartow Police Department joined a county-wide law enforcement software network, called Coplink. The Coplink Program is a regional data sharing program which includes a majority of the Tampa Bay Region, counties and local law enforcement agencies.
Having the ability to readily share criminal justice information is a proven avenue to increase the effectiveness of crime solution.
The Records Section is responsible for processing, maintaining and disseminating department records according to the state and local laws. Retention Maintenance and Destruction are governed by F.S.S. 119 and 257 and the General Records Schedule for Law Enforcement Agencies. This section is responsible for forwarding all documentation to the State Attorney's Office and/or Clerk's Office on all Arrest, Complaint Affidavits, and Citations.
Brandy White, Records Clerk
The Records section includes two (2) clerks and one supervisor. The lobby is staffed and open to the public Monday through Friday 8:00 AM to 5:00 PM. In January 2016, Bartow Police Department launched the Report Writing Program, Tiburon. This is a countywide law enforcement software network. Having the ability to readily share criminal justice information is a proven avenue to increase the effectiveness of crime solution
After hours and during holidays or weekends, the lobby doors are locked for security purposes, however, the telecommunications operators that are working will allow citizens entry through a door bell system.
The Crime Scene Unit of the Bartow Police Department processes crime scenes for latent finger and palm prints, shoe prints, blood stains, bullets, and any other evidence that may be useful in a criminal prosecution. The Crime Scene unit photographs and sketches crime scenes. Different powders and chemicals are used to obtain the latent crime scene prints. A digital camera, and video camera are used to record the scene and evidence.
The Crime Scene unit uses a digital camera to record most scenes and the pictures can be printed in a matter of minutes on a computer or a digital photo printer. The Crime scene unit videotapes training classes, photographs city property that is damaged for city risk management, and fingerprints the public when they need it for employment
The new Crime Scene van purchased in 2014
The City of Bartow adopted a False Alarm Ordinance #1854-A, effective June 21, 1999. If you are an ALARM USER within the City Limits of Bartow, you are required to register your fire/smoke, robbery, burglary, medical, water flow, panic alarm and/or any audible system. All new alarm systems are required to be registered within 30 days of active service, with the Bartow Police Department.
Once you have registered your alarm, you will NOT be charged for the first two (2) incidents, although there will be a charge for three (3) or more incidents.
You may email your Alarm Registration Form to: Kathryn Jones
For more information on the False Alarm Ordinance or to register your alarm system, go to: Ordinances
Alarm Registration Form
©2017 City of Bartow, FL. All Rights Reserved.


text:
With Instructables you can share what you make with the world, and tap into an ever-growing community of creative experts.
Tell us about yourself!
Universal Portable USB Charger
Make your own lightsaber!
Halloween Costumes
Let your inbox help you discover our best projects, classes, and contests. Instructables will help you learn how to make anything!
© 2016 Autodesk, Inc.


text:
Plans by West Fraser Timber Co. Ltd. and Canfor Corp. to close sawmills in the B.C. interior have raised concerns that lumber output in the region will lag demand driven by a rebound in the U.S. housing market.
B.C. interior sawmills operated by firms such as West Fraser and Canfor have been largely relying on timber left over from years ago, when mountain pine beetles decimated forests in the region. The infestation of pine beetles began in the late 1990s and peaked in 2005.
The upcoming mill closings and the prospect of further declines in timber supplies from the B.C. interior helped boost lumber prices Friday. But longer-term lumber exports will be crimped just as demand for forest products increases from the U.S. housing industry, adding to strong buying from China. With large swaths of beetle-infected trees harvested over the years, the supply of damaged timber is declining and there are also annual limits on allowable cuts for the remaining healthy trees in the B.C. interior.
"Once the U.S. gets back to its normal housing activity, the B.C. interior will be producing 5 billion board feet less a year than it produced in 2005," CIBC World Markets Inc. analyst Mark Kennedy said in an interview.
Lumber output from the B.C. interior is forecast to be less than 12 billion board feet this year, down from peak production of more than 15 billion board feet in 2005. At the end of this decade, mills in the region will likely produce less than 10 billion board feet a year of lumber, as the focus shifts back to primarily sourcing new log supplies, undamaged by beetles.
Mr. Kennedy expects another four or five mills might close over the next four years or so, though he doesn't envisage additional closings in the area by West Fraser and Canfor in the foreseeable future.
West Fraser reports its third-quarter financial results Monday. Canfor will release its quarterly report Thursday.
"The peak infestation has died off, but a lot of the beetle-kill wood that's being harvested now has been dead for 10 years in some cases," Mr. Kennedy said. "The longer the tree has been dead, the less useable it becomes. The logs get so degraded that they bust up so much and create so much waste in your mill that the mill can't be run efficiently. A mill would have to use at least 50 per cent green timber with the beetle-kill wood to make a sawmill work."
On Thursday, West Fraser announced that it will close its mill in Houston, B.C., by mid-2014, while Canfor plans to shut down its mill in Quesnel, B.C., next March. But the two companies have agreed to exchange forest tenure rights, with the result being that West Fraser's Quesnel mill and Canfor's Houston mill will emerge healthier than today, when the companies are competing in both markets and struggling to cope with limited timber supplies.
"There is only so much wood fibre out there," Mr. Kennedy said. "West Fraser and Canfor basically recognized where they have a weak position, and they're shoring up where they have a stronger position. West Fraser will pick up more fibre to support its Quesnel mill and have one fewer competitor, and it's a similar thing for Canfor in staking out territory in Houston."
With timber becoming increasingly scarce due to the ripple effect from the damage left by beetles, that prompted West Fraser and Canfor to reach a deal to exchange harvesting rights, Mr. Kennedy said. "They're not closing the sawmills because they think they can have more pricing power. They're doing it because they don't have enough logs to feed them."
The shutdown of West Fraser's Houston mill will affect 225 workers and Canfor's Quesnel closing will affect 209 employees. Canfor said its Quesnel staff will be offered positions elsewhere in the company, while West Fraser will help the Houston workers transfer to the firm's other mills, where possible.Report Typo/Error
Follow @brentcjangon Twitter:
- Canfor Corp$19.250.00(0.00%)
- West Fraser Timber Co Ltd$59.81-0.06(-0.10%)
- Updated June 23 4:00 PM EDT. Delayed by at least 15 minutes.


text:
- Home
- News
- Sports
- Opinion
- Obituaries
- Features
- Special Sections
- Classifieds
- Public Notices
A Lecanto man and woman were arrested early Wednesday morning on drug charges after sheriff's deputies discovered a meth lab at their residence, according to a Citrus County Sheriff's Office report.
If you currently subscribe or have subscribed in the past to the Citrus Chronicle, then simply find your account number on your mailing label and enter it below.
Click the question mark below to see where your account ID appears on your mailing label.
|ZIP Code:


text:
Quote:Actually, they're pretty much against it.It somehow "ruins" the sport and is viewed as savagery in the eyes of Thais.Methinks, MMA is a "truer" art than MT. It doesn't put restrictions or limits on you. I'm more of a western thinker, while they refuse to go against their traditions. Can't blame them though. It's their art after all.-Taison out
Quote: but you can grapple for hours and have little or no damage from it. Where as Knock down and MT leave a lot of bruises on your body.
Night club fight footage and street fights captured
with the world's first bouncer spy cam
to Matrix!
Learn ten times faster with new training method. Learn entire arts
for as little as $10 per disk.
Self Defense
Stun guns, pepper spray, Mace and self defense products. Alarms for personal and home use.
Stop An Urban Gorilla: Get 2 FREE TASER M26C Replacement Air Cartridges With Each New TASER M26C!


text:
Gestalt-binding of tropomyosin to actin filaments
- First Online:
- Received:
- Accepted:
DOI: 10.1007/s10974-008-9157-6
- Cite this article as:
- Holmes, K.C. & Lehman, W. J Muscle Res Cell Motil (2008) 29: 213. doi:10.1007/s10974-008-9157-6
- Citations
- 702 Downloads
We argue that the overall behavior of tropomyosin on F-actin cannot be easily discerned by examining thin filaments reduced to their smallest interacting units. In isolation, the individual interactions of actin and tropomyosin, by themselves, are too weak to account for the specificity of the system. Instead the association of tropomyosin on actin can only be fully explained after considering the concerted action of the entire acto-tropomyosin system. We propose that the low Ka describing tropomyosin:actin interaction, when taken together with the form-fitting complementarity of tropomyosin strands on F-actin and the tendency for tropomyosin to polymerize end-to-end, make possible unique thin filament functions both locally and at higher levels of filament organization.
KeywordsActin Tropomyosin Gestalt Gestalt-binding Gestaltbindung Coiled-coil Troponin Calcium Muscle
Tropomyosin is a two-chained, coiled-coil protein that is found bound to actin filaments in most eukaryotic cells. The tropomyosin coiled-coil itself assumes a helical contour and thus represents a coiled coiled-coil. Tropomyosin molecules link end-to-end to form continuous strands that are wound tightly along the surface of helically disposed actin subunits of thin filaments (for reviews see Perry 2001; Brown and Cohen 2005; Hitchcock-DeGregori 2008; Lehman and Craig 2008). The presence of tropomyosin on actin strengthens thin filaments by increasing their rigidity and reducing their susceptibility to depolymerizing factors. Under the control of troponin and Ca2+ in skeletal and cardiac muscles, and perhaps other factors in most cellular systems including smooth muscles, tropomyosin participates in a molecular switching mechanism to regulate the traffic of myosin motors on actin filaments. Here access of myosin onto actin is gated by tropomyosin, with troponin in the case of striated muscle filaments playing the role of gatekeeper. This is accomplished by azimuthal movement of tropomyosin among different set positions along thin filaments, thereby either exposing or blocking myosin-binding sites on actin (Haselgrove 1972; Huxley 1972; Parry and Squire 1973; Lehman et al. 1994; Vibert et al. 1997; Poole et al. 2006). An intrinsic ability of tropomyosin molecules to undergo such shifts in position on actin at low energy cost is inherent to this steric mechanism (Lehman et al. 2000), and it is troponin that causes tropomyosin to favor one position or another depending on the concentration of Ca2+. This steric mechanism is not just limited to regulating myosin function. Thus, the presence of smooth muscle and non-muscle isoforms of tropomyosin on actin, possibly in concert with caldesmon (Hodgkinson et al. 1997; Hodgkinson 2000; Lehman et al. 2000), no doubt also gate access of a host of cellular actin-binding proteins onto thin filaments (Ishikawa et al. 1989, 1998; Blanchoin et al. 2001; Gunning et al. 2008). However, despite the crucial role played by tropomyosin in actin function, the properties of tropomyosin that contribute to its F-actin binding and lead to its regulatory movements on actin are incompletely understood. In this commentary, we propose a novel mechanism for the tropomyosin–actin association that we call "Gestaltbindung" or "Gestalt-binding" to contrast the interaction with more typically described lock-and-key models involving stereo-specific protein–protein binding. The use of the term is intended to connote several intertwined meanings. Gestalt, a German word for "form", reflects our argument that the native three-dimensional form taken by tropomyosin is designed to match the actin filament surface, a complementarity which we regard as essential for actin-binding. As in Gestalt-theory [a psychological theory developed by von Ehrenfels (1890) and later by his student Wertheimer (1912)], we also argue that the behavior of the whole system cannot be inferred by examining single "atomistic" units (here single tropomyosin molecules) but only emerges from an understanding of the concerted action of the entire system, viz. the elongated tropomyosin strand as a whole on actin. Finally, we argue that mutations leading to perturbations in tropomyosin shape cause a deficit in "Gestaltbindung", in which irrelevant conformers, lacking complementarity to the contours of actin, fail to bind to thin filaments, as if the system were divorced from its collective genomic memory.
Tropomyosin is a modular protein with seven pseudo-repeating units designed to bind to and match the polarity of seven adjacent actin monomers along a 385 Å path of the helical strands of actin filaments (Parry 1975; Stewart and McLachlan 1975; McLachlan and Stewart 1976; Phillips et al. 1986; Brown and Cohen 2005). The binding strength of individual tropomyosin molecules to F-actin is very weak [Ka ~ 2–5 × 103 M−1, Wegner (1980)]. If each pseudo-repeat module binds actin with roughly equivalent affinity, then the Ka of one repeat would be ~3, close to the binding strength of a single salt bridge in proteins, a value so low that thermal energy would readily cause dissociation. The low Ka, atypical of actin-binding proteins, indicates that strong stereo-specific interaction is not a significant factor in F-actin–tropomyosin association.
Tropomyosin only binds to actin filaments because of the collective interactions conferred by linking tropomyosin end on end. Estimates for the equilibrium of the tropomyosin end-to-end association are modest [2–4.5 × 102, Wegner (1980)]. However, the overall effect of gluing tropomyosin molecules together over an F-actin substrate significantly raises the effective binding of tropomyosin to thin filaments by many orders of magnitude (in principle to Ka25 for 25 tropomyosin molecules linked in tandem over a 1 μm distance). Thus, it is hardly surprising that altered tropomyosin molecules that are incapable of forming end-to-end links cannot associate appreciably with F-actin (Johnson and Smillie 1977; Heald and Hitchcock-DeGregori 1988; Cho et al. 1990; Monteiro et al. 1994).
The modular design of tropomyosin
In addition to the continuously repeating, seven amino acid long "heptads" that define all α-helical coiled-coils, tropomyosin displays a unique longer-range period that is roughly forty amino acids long (Crick 1953; Stone and Smillie 1978; Parry 1975; Stewart and McLachlan 1975; McLachlan and Stewart 1976; Phillips et al. 1986). The latter accounts for the seven modular domains of tropomyosin, which traverse seven actin-binding partners along thin filaments. Other coiled-coils present in muscle that lack the 7-fold modular periodicity do not bind to actin (e.g. the rod portion of thick filament associated myosin and paramyosin in invertebrates). However, Nature, unlike the Pythagoreans, did not settle on seven-fold motifs as an ideal application of a perfect number. In fact, most somatic cells contain truncated tropomyosin isoforms with four to six ~40 amino acid-long actin-binding modules designed to bind to shorter stretches of thin filaments (Gunning et al. 2005, 2008).
A series of elegant experiments by the Hitchcock-DeGregori and Tobacman groups (Hitchcock-DeGregori and An 1996; Landis et al. 1999; Rosol et al. 2000; Hitchcock-DeGregori et al. 2001, 2002) showed that strict precision in the modular quantization of tropomyosin is essential for actin-binding. Tropomyosin was truncated by deleting one or more internal repeat modules. When the remaining modules were left intact to conform to the actin filament periodicity, these constructs still bound to actin. In contrast, when insertions or deletions were introduced that changed the lengths of one or another of the modules, the actin–tropomyosin alignment was corrupted and actin-binding diminished considerably. Similarly, substitution of random coils in place of coiled-coil modules abolished actin-binding.
Tropomyosin contains strategically placed acidic residues on the surface of each of its repeating modules. These no doubt interact electrostatically with positively charged residues present on the complementary flat face of actin subunits along thin filaments (Lorenz et al. 1995; Brown et al. 2005). Such an interaction is consistent with sensitivity of tropomyosin–actin binding to monovalent ion concentration (Eaton et al. 1975; Hill et al. 1992; Willadsen et al. 1992). Lacking a high-resolution crystal structure of the actin–tropomyosin complex, the positions of interfacial interactions cannot be plotted unambiguously. Nonetheless, in silico modeling provides strong support for the view that complementary surface charges are matched to each other (Lorenz et al. 1995; Brown et al. 2005; Brown and Cohen 2005).
Tropomyosin lies at a high radius on the actin filament
Shape complementarity of tropomyosin and actin filaments
As described, the binding site for tropomyosin on actin is 385 Å long and made of seven low affinity interactions. Surely the only reason that the tropomyosin binds to actin at all is because it assumes the right shape to interact with seven actins all at the same time. This shape can be deduced from high-resolution crystal structures of segments of the molecule that fit very well to contours of tropomyosin in the Lorenz–Holmes atomic model of actin–tropomyosin described above (Brown et al. 2001, 2005; Li et al. 2002, see Fig. 1B.) These structures also dock extremely well within tropomyosin density envelopes in 3D reconstructions of both Ca2+-treated and Ca2+-free thin filaments (Poole et al. 2006; see Fig. 1C). No obvious reconfiguration of tropomyosin is needed for the fittings. Thus independently determined tropomyosin structures display a conformation which is directly transposable onto the actin filament, without any apparent need for significant coiled coiled-coil conformational flexibility. Hence, these results indicate that the modular sequence complementary of tropomyosin and F-actin, described above, and the shape complementary, described here, are perfectly correlated. More specifically, these studies not only support the hypothesis that tropomyosin is designed to match the contours of actin but also that it is free to move over a flat actin interface without undergoing an obvious change in configuration (Poole et al. 2006).
The presence of roughly periodic groups of alanine clusters (Conway and Parry 1990) in tropomyosin causes local narrowing and bending of the coiled-coil protein (Brown et al. 2001; Brown and Cohen 2005, also see Nitanai et al. 2007; Minakata et al. 2008). This bending likely is partly responsible for the global coiled coiled-coil shape of tropomyosin, which fits so nicely to the F-actin surface. The B-factor associated with the alanine clusters in crystal structures is low, suggesting that the clusters and their surrounds, while bent, are relatively stable. Formally, alanine clusters can bend a fibrous protein in opposite orientations. In fact, there must be a bias in folding of the tropomyosin-coiled coiled-coil, since crystal structures of tropomyosin fit to right-handed helices that match the right-handed F-actin helix. Thus the whole molecule appears to bend collectively when forming the coiled coiled-coil.
We posit that the inherent helical contour of tropomyosin is an essential feature that facilitates the binding of the elongated protein on actin, weak as this interaction might be. Experimental support for this notion comes from studies showing that replacing core alanine residues, responsible for specific bending, with leucine and valine can reduce the binding of such tropomyosin variants to F-actin (Singh and Hitchcock-DeGregori 2003). This observation suggests that disrupting coiled-coil bending reconfigures the tropomyosin supercoil, which is followed by a concomitant loss of complementarity and hence Gestaltbindung to F-actin. Experimental alteration in tropomyosin pseudo-repeat lengths will also have the same effect. Whether or not such mutations cause changes in flexibility of tropomyosin (Singh and Hitchcock-DeGregori 2003, 2006) may not be as relevant a consideration.
End-to-end polymers of tropomyosin bind tightly to actin filaments
The head-to-tail polymerization of tropomyosin on the surface of actin filaments generates a larger scale level of thin filament organization that is functionally transformative. As mentioned, tropomyosin assembly and binding on actin is only effective once these end-to-end links are formed. In fact, experimental manipulation that interferes with tropomyosin strand formation (e.g. expressing unacetylated tropomyosin constructs or removing tropomyosin ends) fixes the system at the lower level of organization and prevents effective actin-binding (Johnson and Smillie 1977; Heald and Hitchcock-DeGregori 1988; Cho et al. 1990; Monteiro et al. 1994). There appear to be multiple mechanisms for ensuring that distinctive ends of different tropomyosin isoforms adhere to each other and several structural models have been offered for the process (McLachlan and Stewart 1976; Greenfield et al. 2006; Murakami et al. 2008). Understanding the specificity of the tropomyosin–tropomyosin connections is important. However, of possible greater importance is recognition that only minimum energy cost may be needed to bias tropomyosin into polymeric strands and thus allow the protein to work as part of an unbroken cooperative system, where Aristotle's dictum, "The whole is more than the sum of its parts" applies. The Gestalt of the thin filament system as a whole can only then structure how the parts behave.
Clear and convincing evidence indicates that, in the complete absence of any accompanying actin-binding proteins, muscle and non-muscle isoforms of tropomyosin bind to actin with great precision and regularity (Lorenz et al. 1995; Lehman et al. 2000; Skoumpla et al. 2007; Maytum et al. 2008). Binding of the two proteins to each other is an innate property that is intrinsic to the design of tropomyosin and actin filaments. However, given the diversity of tropomyosin isoforms, particularly those in non-muscle cells (Gunning et al. 2005, 2008), it is not surprising that different tropomyosins show differences in their affinity for actin (Pittenger et al. 1995). This potentially could result from subtle changes in surface charge, in overall coiled coiled-coil shape and flexibility, or in the end-to-end molecular bonding of tropomyosin. It is also possible that extrinsic factors such as ancillary actin-binding proteins may modulate the conformational landscape of the actin filament to influence Gestalt-binding (cf. Hill et al. 1992). In addition, actin or tropomyosin binding proteins such as troponin-T and caldesmon may tether tropomyosin to actin, thus stabilizing assembled thin filaments (Hill et al. 1992; Pittenger et al. 1995).
Proposed scheme for tropomyosin binding to actin filaments
We thank Ms. Karen Moore (Moore Design) for artwork in Fig. 2. We also thank the restaurant staff at Schloss Schwetzingen for allowing the authors to first discuss Gestaltbindung a bit past closing hours. This research was supported by grants from the National Institutes of Health to W.L. (HL36153, HL86655).
Open Access
This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.


text:
© 2012 American City Business Journals. All rights resereved. Use of this Site constitutes acceptance of our User Agreement (updated 3/14/12) and Privacy Policy (updated 3/14/12).
The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of American City Business Journals.
Forums: Admins | Moderators
Lacrosse news straight to your inbox.
Tuesday November 5th, 2013 1:45am
Updated: October 8, 2013 3:06 p.m.
Nineteen Louisville lacrosse alumnae released a letter monday night defending coach Kellie Young. The letter can be seen at USAToday.com.
Updated: October 7, 2013 10:06 p.m.
AP writer Gary Graves is reporting that Louisville will take no disciplinary action regarding allegations of verbal abuse by lacrosse coach Kellie Young. Kenny Klein, a spokesperson for Louisville athletics, disputed some of the claims made in the Courier-Journal report and said the school has addressed the matters involving Young.
October 7, 2013 9:05 a.m.
Amid allegations of verbal abuse in a Courier-Journal report on Saturday, Louisville coach Kellie Young led the Cardinals at the Stick it to Sarcoma tournament at Johns Hopkins on Sunday.
"It's fun to watch this team compete with the passion they're putting out on the field," Young said following Louisville's scrimmage against Rutgers, their third of four games on the day. "Every day we're trying to coach them to be the best version of themselves and give it everything they have, and we've seen that in every game today. I'm over-the-moon proud of my team."
Young was not able to comment on the Courier-Journal story, but there was plenty of support for her evident throughout the day. Mark Morissette, the father of sophomore midfielder Kaylin Morisette, tweeted in response to @ILWomen, "I wouldn't want my daughter at any other school playing for any other coach."
Mary Bushway, mother of senior midfielder and team captain Hillary Bushway, also had nothing but positive things to say about Young, noting the impact she has had on her daughter as a player and as a person.
Former Louisville midfielder Katie Oliverio, who graduated in May and spent five seasons as a player under Young, was in attendance on Sunday and had a similar perspective. Oliverio said the culture at Louisville when she arrived on campus following the program's first season in 2008 was troubled and that Young was responsible for turning things around, cultivating a winning culture and motivating players to reach their potential. She added that she would not be the person she is without Young.
A Louisville spokesperson said the athletic deparment had no statement regarding the report.
Louisville next hosts Michigan for a scrimmage on October 12. There will be more from the Stick it to Sarcoma event, including notes from each team, available soon on ILWomen.com.


text:
FRITZ!Box 7340 Service - Knowledge Base
AVM Content
Calls cannot be made to premium-rate numbers
You cannot use a telephone connected to the FRITZ!Box to make calls to premium-rate telephone numbers. Instead, you either hear a busy signal or a message stating that the number cannot be reached.
Important:Some of the settings described here are only displayed if the advanced view is enabled in the user interface. The configuration procedure and notes on functions given in this guide refer to the latest FRITZ!OS.
1 Creating dialing rules for premium-rate numbers
Some Internet telephony providers do not allow you to dial premium-rate numbers. Therefore, configure the FRITZ!Box so that it makes calls to premium-rate numbers over your landline:
Important:For this, the FRITZ!Box must be connected to a landline (analog or ISDN).
- Click "Telephony" in the FRITZ!Box user interface.
- Click "Call Handling" in the "Telephony" menu.
- Click on the "Dialing Rules" tab.
- Create a dialing rule for premium-rate numbers so that calls to these numbers are made over your landline.
- Click "OK" to save the settings.
Note:You can find detailed instructions on creating dialing rules in the FRITZ!Box's help. To open it, click the "Help" icon in the FRITZ!Box user interface.


text:
Bleach Blonde Rihanna's Late Night in LA
Posted Friday February 3, 2012 10:07 AM GMT
She's always up for a good time, and last night (February 2) Rihanna was spotted partying in Hollywood with some friends.
The "We Found Love" songstress looked to be thoroughly enjoying herself as she exited The Roxbury night club sporting a striped orange top and bleached blonde hair.
Ri-Ri noted that her newly-lightened coif was designed for her upcoming Elle magazine cover photo, and it looks amazing.
Sharing with her fans, Rihanna tweeted, "#Back2Work 1st Cover of the year!!! #ELLE. Bleach + weave #WERQ."
Enjoy the pictures of Rihanna at the Roxbury night club in Hollywood (February 2).
Photo Credit: PacificCoastNewsOnline.com


text:
Site design selection
The old design is no longer fully supported nor does it get full attention when we roll out new features. We strongly recommend using the new design.
Member: Aerulan
Books6,577 books cataloged
Recommendations12 recommendations
Favorite authorsPatricia Briggs, Steven Brust, Emma Bull, Julie E. Czerneda, Barbara Elsborg, P. C. Hodgell, Patricia A. McKillip, Robin McKinley, Cherie Priest, Deanna Raybourn, R. Lee Smith, Sherwood Smith, Dianne Sylvan, Martha Wells, Patricia C. Wrede (Shared favorites)
Also onRavelry
Account typeprivate, lifetime
Member sinceFeb 18, 2006


text:
Learn how to protect yourself from Internet scams. Read our online fraud prevention tips
Other Stuff ClassifiedsFor Sale Local NY Classified Ads
65 listings match, 21-30 shown
Can't find what you're looking for? Try our
Advanced Search
Do you require Standby Letter of Credit to complete your Imports? We can provide. We, Bronze Wing Trading LLC offers Standby LC through our trade finance facilities on behalf of our clients to fulfill their financial commitment with their suppliers. We will structure your SBLC requirement as per your transaction needs that protect your business interests. We have different proven methods that work effectively to achieve our client's commercial goals.We also offer other Financial Instruments, which are; Letter of Credit MT700 Letter of Comfort Bank Guarantee MT760 Advance Payment Guarantee Performance Guarantee or Bond Tender Bond or Bid Bronze Wing Trading isn't limited to any specific country or region; we operate worldwide and reach out our clients around the world. Why you've to choose Bronze Wing Trading? Bronze Wing Trading is a company you can trust on for your trade finance requirements. With years of experience & reputation in international market, we provide complete solution and support our clients. Further, to conduct our client's trade transactions in a quick and efficient way, we offer them with some attractive benefits, which are below; Good Rated International Banks No Tangible Collateral Required Quick Approval & deal completion in one banking day (T&C applies) Worldwide Approach Escrow Payment Option If you want to conduct your deal without tying up your cash margin – Obtain SBLC (MT760) or any other banking instrument from Bronze Wing Trading. To Get Standby Letter of Credit send your requirements on: firstname.lastname@example.com OR visit: www.bwtradefinance.com
Web Id: SYR16390209
Published on Syracuse.com 6/4. Updated 6/4.
Looking for Letter of Credit? We can help you. We, Bronze Wing Trading is a Leader in Trade Finance Market and are direct providers of Letter of Credit globally. We are structuring Trade Finance for our customers from decades and have a reputable influence in international market with proven results. We are also facilitating other Trade Finance Facilities; Standby Letter of Credit MT760 Letter of Comfort Bank Guarantee MT760 Advance Payment Guarantee Tender Bond or Bid Performance Guarantee or Bond Bronze Wing Trading helped numerous traders worldwide from Europe to United States and Africa to Asian Countries. Why Bronze Wing Trading is best solution for your business? Because of our years of trade finance experience and knowledge we can successfully complete your deal without any hassle. Plus, we care about our clients that is why we provide them our services with some unique benefits; No Financial Collateral Required Best Rates Top-Rated Banks Deal Completed Within a day (T&C applies) Globally Available If you require Letter of Credit or any other financial instrument, Bronze Wing Trading is here to help you. To Get Letter of Credit (MT700) e-mail us now: email@example.com OR visit Bronze Wing Trading's Website: www.bwtradefinance.com
Web Id: SYR16380035
Published on Syracuse.com 6/1. Updated 6/1.
Moving Box New York offer discount brand new moving boxes kit supplies and Fast free delivery to : New York, Brooklyn, Arverne, Auburn, Astoria, Bellmore, Brighton, Bronx, Central Islip, Forest Hills, Jamaica, Long Island City, Greeport, Flushing, Ithaca, Mamaroneck , Rego Park, White Plains, Arverne, Manhasset, Pelham, Potsdam, Ridgewood, Rye, Somers, Staten Island, TriBeCa, Amherst, Ardsley, Bayside, Bethpage, Brentwood, Bronxville, Buffalo, Chatham, Cohoes, Cooperstown, Delhi, Elmhurst, Elmont, Fishkill, Fresh Meadows, Glen Cove, Great Neck, Hempstead, Howard Beach, Hudson Falls, Huntington, Jackson Heights, Kew Gardens, Lindenhurst, Little Neck, Liverpool, Manhattan, Massapequa, Mastic, Middle Valley, Mineola, Montrose,, N Massapequa, North Tonawanda, Oakland Gardens, Ossining, Oyster Bay, Ozone Park, Peekskill, Plainview, Poughkeepsie, Queens, Queens Village, Rochester, Roosevelt, scarsdale, Southampton, Springfield Gardens, Springwater, Tarrytown, Troy, Tuckahoe, Union, Woodhaven, Woodside, Yonkers, Albany, Babylon, Bethlehem, Carmel, Elmira, Jamestown, Rome, Syracuse, Thousnad Islands, West Babylon, Westchester, Whitestone, Yorktown and other Cities in New York. 25 Small Moving Boxes : Small Boxes Ideal for small heavy items 25 - 16x10x10 Shipped WITH a protective cover to ensure safe delivery $35.00 20 Medium Moving Boxes:More Boxes More Space 20 - 18x14x12 Shipped WITH a protective cover to ensure safe delivery $41.00 12 Large Moving Boxes : Larger Boxes More Space12 - 20x20x15 Shipped WITH a protective cover to ensure safe delivery $41.00 10 Extra Large Moving Boxes Bundle of 10: 23 x 23 x 16EXTRA large Moving Boxes Bundle of 10 EXTRA large Moving Boxes Shipped WITH a protective cover to ensure safe delivery Only: $44.28 Economy Moving Box Kit #1 15 Boxes, Fewer Supplies, and 22 cu.ft. of space 5 Small moving boxes 16 x 10 x 1010 Medium moving boxes 18 x 14 x 12 110 yards of Tape 1 Marker Only $39.99 Basic Smart Moving Boxes Kit #1 (18 boxes, $32 in Supplies, and 24 cu.ft. of space) 9 Small Moving boxes 16 x 10 x 10 9 Medium Moving boxes 18 x 14 x 12 4 Rolls of SmartMove Tape $10 Value! 1 ClamShell Tape Dispenser 24' of Bubble Wrap 3 lbs of Wrapping paper 1 Marker Only $49.95 Bigger Boxes - Smart Moving Kit #1 (14 Boxes, $47 in Supplies, and 30 cu.ft. of space) 11 Medium moving boxes 18 x 14 x 12 3 Large moving boxes 20 x 20 x 15 4 Rolls of SmartMove Tape $10 Value! - 1 Bed Room- 1 Living Room- 1 Kitchen- 1 Bathroom 1 Heavy Duty Dispenser 3 lbs of Wrapping paper 1 Marker Only $52.00
Web Id: SYR16139685
Published on Syracuse.com 6/1. Updated 6/1.
Bronze Wing Trading LLC is a Dubai based company, working as direct Trade Finance providers in International market since decades. Our arrays of customers are commodity traders, manufacturers, producers, general traders, and contractors. We provide a complete solution to support your businesses by structuring your transactions with our extensive trade knowledge, professionalism and years of experience in trade finance. We Offer You: We have a broad range of trade finance services to help your business need. Below you will find the following facilities: • Import Letter of Credit MT700 • Letter of Comfort • Bank Guarantee MT760 • Standby Letter of Credit MT760 • Advance Payment Guarantee • Tender Bond or Bid • Performance Guarantee or Bond Working with Bronze Wing Trading & it's Benefits: Our services are credible and proved to be trusted by clients that face the enigma of reaching the Trade Finance Facilities. Which you can easily obtain by reaching out to us, so here is what you can get if you choose our trade finance services: • You will get your required Instruments from Good-Rated European Banks • No cash margins are required to avail our trade finance facilities • We strive to close any deal in just a day (T&C apply) • We provide our clients with escrow option to secure their payment • With decades of experience in trade finance, we hold to our reputation as we render our services effectively • We are trusted worldwide and provide the best trade services to every client to make their deal and transactions successful No matter which part of the world you are in, you're just one click away from us. To Get Free Quote, go to our website: www.bwtradefinance.com or send your enquiry at: firstname.lastname@example.com
Web Id: SYR16369916
Published on Syracuse.com 5/29. Updated 5/29.
Look at these 2 beautiful burial plots in historic Oakwood Cemetery near Syracuse University! They are located at the top of a hill with a panoramic view of the cemetery. The current cost would be $550 each if you bought them directly from Oakwood Cemetery. I'm charging only $499 for both of them, that's less than half price! They are in Section 76, Lot 61, Plots 1 and 2. Call or text 315.414.6980.
Web Id: SYR15335079
Published on Syracuse.com 5/3. Updated 6/2.
Elite Creed Natural provide all natural handmade soaps and skincare products. You can purchase online at www.EliteCreed.com Products include: natural soaps, lotions, bath bombs, whipped body butters, and more
Web Id: SYR15959293
Published on Syracuse.com 12/29. Updated 5/29.
framed 1955 Marilyn Monroe nude calendar 12x22 conservation glass and backing frame black call bill 315 451 2028
Web Id: SYR15873454
Published on Syracuse.com 11/23. Updated 6/10.
65 listings match, 21-30 shown
Find A Local Business


text:
Call the school office @ 330-966-1617 if you would like more information about our school and/or to request a tour.
We are located on the serene 50-acre Fieldcrest estate in North Canton!
Thank you for your interest in the Weaver Child Development Center! We believe that your child is a special creation of God and that s/he will thrive in an environment that is safe and supportive. Through guidance in a loving environment, your child can develop his or her God-given talents.
Research proves that these early years are the most important in a child's life. The foundations of all later learning are laid during the early childhood years, and intelligence develops as it is nurtured.
Thank you for your interest in our programs, and please don't hesitate to contact us if you have any questions or concerns.
Inclement Weather Reminder: If Plain Local Schools are CLOSED or DELAYED then Weaver CDC is CLOSED.


text:
My Contacts Backup
By GLOBILE BILISIM BILGISAYAR HIZMETLERI ILETISIM DANISMANLIK SANAYI TICARET LIMITED SIRKETI
Open iTunes to buy and download apps.
--- Since 2011 over 5.000.000 iPhone and iPad users preferred our app to backup their contacts. Thanks you all for great & encouraging reviews. ---
"No signing in, no accounts, no activations, just send your contacts in a universal format to yourself or others through the mail app. This app backs your contacts up, or simply transfers them in a simple, tangible way that just about every device can read. Bravo!"
My Contacts Backup is the easiest way to backup and restore your contacts all from your phone without needing a computer or synchronization. You can backup all your contacts with a single touch and send them to yourself as a .vcf attachment via email.
All contacts can then easily be restored any time by simply opening the .vcf file in your mailbox with iOS Mail app.
Key Features:
* Offline Backup. No need to sync to any server. Just email the backup file to yourself.
* Easy restore. No need to use any app to restore backup file. Just tap on the *.vcf backup file in the iPhone, iPod Touch or iPad Mail client and restore your contacts for FREE.
* In App vCard Restore Feature
* Set REMINDER to backup regularly (weekly or monthly)
* Easily transfer contacts between iOS Devices using just email client.
* Backup Contacts as VCF (VCard) or Export Contacts as CSV (Excel) file
* Delete All Contacts in Address Book
* VCF backup is limited to max 500 contacts. You need to download PRO version for unlimited contacts backup.
IMPORTANT NOTE: After sending backup file (*.vcf) to yourself, please check your inbox to see if message arrived and contains attachment (backup file). Sometimes email providers block attachments if attachment size is too large. Try with another mail account if possible, to send your backup file.
What's New in Version 2.3.1
* Minor bugfixes
If you are interested in TV Series, don't forget to check out our new app "My TV Episodes" :)
Customer Reviews
Very good App
Works excellent
Customers Also Bought
- Free
- Category: Productivity
- Updated: 11 April 2016
- Version: 2.3.1
- Size: 23.1 MB
- Languages: English, Catalan, Croatian, Czech, Danish, Dutch, Finnish, French, German, Greek, Hungarian, Indonesian, Italian, Japanese, Korean, Malay, Norwegian Bokmål, Polish, Portuguese, Romanian, Russian, Simplified Chinese, Slovak, Spanish, Swedish, Thai, Traditional Chinese, Turkish, Ukrainian, Vietnamese
- Developer: GLOBILE BILISIM BILGISAYAR HIZMETLERI ILETISIM DANISMANLIK SANAYI TICARET LIMITED SIRKETI
- © OBSS Mobile 2015
Compatibility: Requires iOS 7.0 or later. Compatible with iPhone, iPad and iPod touch.
Top In-App Purchases
- In App vCard RestoreRs 100.00


text:
Vjem.com.br - Vjem Website Traffic Estimation
We have pulled stats for you about vjem.com.br to help your research.
Based on Alexa.com findings, vjem.com.br has a global traffic rank of 1,650,568. vjem.com.br also reaches roughly 482 unique users each month and has 7 backlinks according to Alexa. The estimated monthly ad revenue is $ 0.00.
We estimate the website value of vjem.com.br is currently at $ 0.00. Traffic and Revenue of vjem.com.br is estimated to be decreasing within the last 3 months. The Site was launched at Tuesday, 09 October 2001 and is 15 years and 8 months old. The domain vjem.com.br is a .com.br domain with the name vjem preceding it.
The Server of vjem.com.br is powered by the Apache/2.2.25 (Unix) mod_ssl/2.2.25 OpenSSL/1.0.0-fips mod_auth_passthrough/2.1 mod_bwlimited/1.4 webserver software and the server is physically located in Canada (Quebec) and uses the IP address 220.127.116.11. The average loading time of vjem.com.br is 4450 milliseconds - this is faster than 18% of all other websites. At the DMOZ open directory project we found no listing for vjem.com.br at this time.
Updated: 06/20/2017 15:39, 2 days ago
|Worldwide Rank
|Monthly Users*
|Monthly Pageviews*
16 per day*
95 per day*
|Website Value*
|Monthly Earnings*
|Daily Earnings*
|$ 0.00⇓
|$ 0.00⇓
|$ 0.00⇓
|*Estimated Traffic and Value Data
Site TitleImobiliária Vitrini
Site DescriptionNo description for vjem.com.br at this time.
Keywords and Tags
Below you will find additional research and charts about vjem.com.br.
Be sure to leave any comments about vjem.com.br using Facebook below.
Estimated Value and Traffic
Traffic Charts
Alexa Traffic Trend
Alexa Reach
Compete.com Traffic Chart
Google Trends
Server InformationThe webserver of vjem.com.br is powered by Apache/2.2.25 (Unix) mod_ssl/2.2.25 OpenSSL/1.0.0-fips mod_auth_passthrough/2.1 mod_bwlimited/1.4 webserver software. The server is located in Montréal in Canada. The IP address of vjem.com.br is 22.214.171.124.
More detailed:
|IP Address
|AS Number
iWeb Technologies Inc.
|iWeb Technologies
|Montréal, Quebec, Canada
Bookmark or share this sitePermalink for this site:
Or bookmark / share this:


text:
- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
About this Journal
International Journal of Telemedicine and Applications is a peer-reviewed, Open Access journal that aims to bring together science and applications of medical practice and medical care at a distance as well as their supporting technologies such as, computing, communications, and networking technologies with emphasis on telemedicine techniques and telemedicine applications. It is directed at practicing engineers, academic researchers, as well as doctors, nurses, etc.
International Journal of Telemedicine and Applications will highlight the continued growth and new challenges in telemedicine, applications, and their supporting technologies, for both application development and basic research. Papers should emphasize original results or case studies relating to the theory and/or applications of telemedicine. Tutorial papers, especially those emphasizing multidisciplinary views of telemedicine, are also welcome. International Journal of Telemedicine and Applications employs a paperless, electronic submission and evaluation system to promote a rapid turnaround in the peer-review process.
International Journal of Telemedicine and Applications currently has an acceptance rate of 11%. The average time between submission and final decision is 59 days and the average time between acceptance and publication is 47 days.
International Journal of Telemedicine and Applications has recently been accepted for coverage in the Emerging Sources Citation Index, which is the New Edition of the Web of Science that was launched in November 2015. This means that any articles published in the journal will be indexed in the Web of Science at the time of publication.


text:
Homemade Hot Fudge Sauce
This homemade hot fudge tastes delicious on our Ice Cream Sundae Trifle.
- Yield: Makes 2 cups
Source: The Martha Stewart Show, Episode 5090
- 2 ounces unsweetened chocolate
- 1/2 cup unsalted butter
- 2 cups superfine sugar
- 1/2 cup evaporated milk
- Pinch of coarse salt
Melt the chocolate and butter in a small saucepan over medium-low heat. Alternately add sugar and milk in two additions; whisk to combine. Add salt and continue whisking until sugar is dissolved, about 5 minutes. Serve warm.


text: About Andrea's Andrea's is a partnership between Wynn Las Vegas and Sean Christie's Las Vegas Nightlife Group. Open seven nights a week from 5:30 p.m. until 2 a.m., Andrea's offers a full menu until 11 p.m. and a late night menu until 2 a.m. on Friday and Saturday nights when there will be a free flow between Andrea's and Surrender Nightclub where diners can enjoy special privileges including line bypass. For reservations, please call 702-770-DINE (3463). For more information, please visit www.wynnlasvegas.com.SOURCE Wynn Las Vegas


text:
Conrad Slashes International Affairs Budget request
Yesterday, Senate Budget Committee Chair Kent Conrad (D-ND) cut President Obama's FY11 International Affairs Budget request by $4 billion, or 7%, ignoring bipartisan Senate support and calls from national security leaders to bolster funding for development and diplomacy. Most troubling of all is that Conrad's entire cut to discretionary spending in the FY 11 budget is taken from the International Affairs Budget. The USGLC released a statement calling Conrad's move "deeply disappointing," and that "with the global challenges our nation faces, we cannot afford to neglect such vital components of our national security." Throughout his tenure as Budget Chairman, Sen. Conrad has consistently cut the International Affairs Budget. Last year Sen. Conrad cut the President's request by a similar amount, but full funding was restored by a Kerry-Lugar amendment on the Senate floor.


text:
21 Apr
Engineer Enfocus - Bangalore - Kollmorgen
- Position
- Engineer Enfocus
- Company
- Kollmorgen
- Location
- Bangalore KA
- Opening
- 21 Apr, 2017 30+ days ago
Kollmorgen as the company that open the jobs vacancy, have some qualification and spesification especially for the Engineer Enfocus jobs vacancy. To find out more information and about qualification and spesification details, walkin interview schedule, the address of the company, the company contact info (email/phone number) of Kollmorgen company, please start to apply for the job vacancy with fill the jobs application with click the 'Apply This Job' button below.
QA Engineer - Enfocus
About Us
Esko is a global supplier and integrator of innovative solutions for packaging, commercial printing and professional publishing. Our company is a dynamic market leader in state-of the-art software for packaging buyers, designers and manufacturers and hardware products (CDI computer-to-plate imagers, flexible cutting & creasing tables) for the packaging, label, sign and display industries. With Headquarters in Belgium (Ghent), Esko employs over 1,500+ people worldwide. Its global sales and support organization covers Europe, the Americas, Asia/Pacific and Japan.
Main role / Job Objective:
Enfocus is looking for a QA Engineer position for Global Resource Center (GRC) located in Bangalore, India. The candidate will be part of a global team to jointly work on product engineering of the Enfocus products. The candidate should be willing to pursue his career in Software QA and will be responsible for assuring the quality of the software within the defined product group.
Main responsibilities and key activities: o
Responsible for quality check for Enfocus software o
Responsibility: o
Responsible for evaluating, planning and executing test cases for software applications o
Contribute to release process - Responsible for product Alpha, Beta and Release test programs. Also maintain release notes o
Review user stories and technical specifications and work with R&D engineers to create and write test cases and test plans o
Document the test cases, test plan, test result and responsible for defect management o
Improve test methodology and tools, set up automatic testing o
IT - Install, configure and maintain product, data, tools, databases and test environments (FTP, Web Hosting, 3rd Party applications, etc.) o
Support - Third-line support for customers questions in collaboration with the Software Engineers
Qualifications and professional knowledge:
- Education: Bachelor degree in informatics or Graphics or Print Industry
- Languages: English required, any other language highly appreciated
- Knowledge of software testing theory, application and tools an advantage
- General interest in IT and web server technologies in particular
- Background or knowledge of the graphical market is an asset; in particular knowledge of Esko/Enfocus products and Adobe InDesign, Illustrator, Photoshop
Desired Quality :
- Communication
- Communicate with software engineers about the quality and user friendliness of software
- Communicate application knowledge with other departments including sales, marketing and customer service
- Document usage and contribute to the knowledge database
- Scrum – Knowledge in Scrum or Agile software development process is an added advantage
- Scripting Knowledge – Knowledge on any scripting language, JavaScript, PHP, Apple script or VB Script is an added advantage
Danaher Corporation Overview Danaher is a global science & technology innovator committed to helping our customers solve complex challenges and improve quality of life worldwide. Our world class brands are leaders in some of the most demanding and attractive industries, including life sciences, medical diagnostics, dental, environmental and industrial solutions. Our globally diverse team of 59,000 associates is united by a common culture and operating system, the Danaher Business System, which serves as our competitive advantage. We generated $16.5B in revenue last year. We are ranked #133 on the Fortune 500 and our stock has outperformed the S&P 500 by more than 2,000% over 20 years.
At Danaher, you can build a career in a way no other company can duplicate. Our brands allow us to offer dynamic careers across multiple industries. We're innovative, fast-paced, results-oriented, and we win. We need talented people to keep winning. Here you'll learn how DBS is used to shape strategy, focus execution, align our people, and create value for customers and shareholders. Come join our winning team.
Organization : Esko
Job Function : Engineering
Primary Location : Asia-India-Karnataka-Bangalore
Schedule : Full-time


text:
congrats :cheers:
Rec'd the $15 Barnes and Noble Gift Card I won on the 1st Herbal Essence IW Game
:sunny: Congratulations on your win!
congrats on the win :cheers:
As always...Thank you all!!! This forum Rocks!! :headbang: Everyone here is so nice!!! Always supporting each other!!
Nice Win ENJOY
Great win! Congrats!
There are currently 1 users browsing this thread. (0 members and 1 guests)


text:
Marc By Marc Jacobs 'indigo' Colorblock Sweater Dress
Like a 1960s flight attendant. Very cute mod yellow, color block dress from Marc Jacobs.
Cute fitted top that works well for both work and play!
Serena has an androgynous style about her and this button down shirt is the perfect staple to achieve that look.Tags: fashion, style, apparel, white, button down, Vince, gossip girl, gossip girl fashion, serena van der woodsenAdded 9 Years Ago from ShopBop
First of all, Vince clothing is by far the MOST comfortable. Second of all oversized is also comfortable. By the transitive property this shirt is the most comfortable shirt ever.
Splendid always makes great basics that you can wear again and again. I love the length on this cardigan and the banding at the cuffs and waist. V-neck cardigans clearly aren't just for Mister Rogers anymore.
A basic oatmeal cardigan + a few hot pink stripes = a perfectly fun sweater for fall.
What ever will you wear with the fabulous deco jewelry you're acquiring? I recommend Diane Von Furstenberg's Goslar Cardigan. Retro chic at its best, in wool for warmth when you need it, you cannot go wrong with a fun cardigan.
maybe this will make me more like an Olsen...
It is difficult to guess which decade this blouse was born, but lucky for us, it's brand new! This Tucker print top is lovely layered or alone - and as Agyness Deyn would instruct, don't be afraid to mix colors or patterns.


text:
rally race cage
does anybody know where i can get a rally race cage for my zx3
it would have to be made. you being by miami should yield you alot of quality shops to build you one. try finding a shop that builds drift cars or time attack cars (should be real easy in south fl) as they are usually very experienced in cage building.
Check out this thread...
Mitch does rally cages as well...
For actual rally racing cages have to be FIA approved consult rule books for a proper regulations on cages.
^^ Only for FIA sanctioned events.
SCCA uses a different rule set.
Rally America is seriously considering making FIA spec the new standard in this country. If you build your cage to FIA spec, it will essentially be accepted everywhere. Consult the rule book of the sanctioning body/bodies you intend to complete with if you are attempting to build to the lowest common denominator. Please remember that in addition to being one of your most valued safety devices, a great cage enhances the performance of the vehicle more than a merely adequit cage.
Well said.
Regardless of your racing activity, the more you invest in safety, the more perofrmance you can achieve. If anything from a peace of mind standpoint.
A good cage helps with a vehicle's rigidity and that translates into better handling.
Like with anything, buy the best you can afford. Especially with safety, don't cut corners and go on the cheap.
The required Rally America cage rules are just a few bars short of FIA requirements anyway. Contact Grassroots Motorsports Magazine. They're in Ormond Beach and should be able to give you the names of good cage builders in Florida.
|All times are GMT -5. The time now is 02:18 PM.
Powered by vBulletin® Version 3.8.8
Copyright ©2000 - 2017, vBulletin Solutions, Inc.
Search Engine Optimization by vBSEO 3.6.1
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.


text:
So I need Ideas Just In Case
View Single Post
View Public Profile
Send a private message to curlypearl
Find More Posts by curlypearl
Join Date: Jun 2008
Posts: 11,603
Monday, April 29, 2013 at 12:57AM
Hi h2wQueen, I have been doing roller sets during the cooler weather.
The thing I have noticed is that first of all your hair MUST be totally dry before you remove the rollers otherwise it will frizz into an awful mess. Also, when you first take out the rollers it is likely to be extremely poufy and at first you may freak out, but take heart. Eventually it settles down. Usually my second day is a lot better than my first and 3-4-5 are great also.
If you used a lot of setting lotion the pouf will look like a volcano! I use much less when I do my hair this way than when I do it curly. You want to contain the pouf, not encourage too much volume. This style creates enormous volume (at least on me).
It may help to settle the pouf by winding a scarf tightly around your head for about ten minutes. Do the reverse of what we do for the curly look, meaning it is good to keep smoothing and touching it and brushing and in particular, combing through it. The idea is to get it to become smooth and sleek. I also use VO-5 conditioning cream on it once it is dry, or an antihumectant like Aveda Brilliant. Hairspray might work also.
I'm very interested to know how it works out for you. If it is done correctly, it can look really pretty, soft and elegant. Please post back and best of luck!
2/c Coarse hair med. density.
Highly porous. Color over grey.
I love all the Curl Junkie products. Still experimenting with gels and curl creams. Still hoping for 2nd day hair....
Every day is a gift


text:
MONTERREY, MEXICO – Mexican authorities are investigating why a band that performed love songs was kidnapped and killed by gunmen, who dumped their bodies in a well in the drug cartel-infested north.
The killings underscored yet again the pervasiveness of Mexico's grisly drug violence, which has claimed more than 70,000 lives since the 2006 launch of a military crackdown on the powerful, feuding cartels.
Authorities said late Tuesday they had pulled 17 bodies from a desert well in the northern state of Nuevo Leon since Sunday, with 14 confirmed so far as members of the band Kombo Kolombia.


text:
Furazolidone Sale No Prescription? Top Online Pharmacy Where You Can Order Furazolidone Online With No Prescription. The Best Place where you can Order Furazolidone From Trusted Pharmacy.
Fast & Discreet Worldwide Delivery!
Buy Furazolidone Online And Save Your Money!24/7 Customer Support.
Free Consultation!
Really Amazing prices
TOP Offers Furazolidone Online, Click Here!
buy cod Furazolidone online without script in HI Paauilo
Furazolidone generic drug
drugs Furazolidone prescription drugs at Staithes
buy Generic Furazolidone online fedex in Maesteg
no prior perscription Furazolidone in MS Poplarville
where to buy Furazolidone price list
buy cheap buy Furazolidone online uk
Furazolidone overnight cod no prescription in Omaha
is Furazolidone a generic medication mastercard in Simonsbath
buy cod Furazolidone overnight no prescription at Broadstairs
Furazolidone us online pharmacist in Vermont Isle La Motte
low cost price gift Furazolidone jellypack online cheap
Furazolidone online free shipping at AZ Salome
buy Furazolidone without prescription at DE Yorklyn
where to buy Furazolidone is available in generic form
order Furazolidone creditcard
purchase cheap Furazolidone online
buy Furazolidone online pills no rx at Utah Huntington
purchase Furazolidone rx no doctors in Blandford Forum
cheap Furazolidone without perscription
purchase Furazolidone pill in Utah
order Furazolidone american express without prescription uk in Pontardawe
buy Furazolidone online in australia
generic Furazolidone next day
Us Furazolidone fedex
Furazolidone no rx needed cod accepted
price Furazolidone in Derry
discount prices on Furazolidone
american pharmacies for generic Furazolidone buy online cheap generic
Buy online Furazolidone High Quality Guaranteed
order Furazolidone prescription price in Nebraska Byron
buy Furazolidone without prescription pay cod
mastercard Furazolidone discounts
Best Price Generic Furazolidone From US Quality
buy online rx Furazolidone without Miami Beach
no prescription Furazolidone online saturday shipping
Generic Furazolidone online pharmacy no prescription at Lewes
cheap Furazolidone no rx in FL
Furazolidone generic equilalent at St Austell
Generic Furazolidone With No Prescription Online
generic Furazolidone online medicine at Ewloe
switching to generic Furazolidone at WI Mount Sterling
buy Furazolidone in Prince George
how long is Generic Furazolidone good for at KS Paola
prescriptions for less Furazolidone at Indiana Oakville
buy Furazolidone without prescription in Stoke-by-Nayland and Nayland
Furazolidone Online No Prescription at Palermo
purchase Furazolidone online cod accepted at Utah Garden City
online compare Furazolidone prices in Arizona
order Furazolidone no prescription in Blanchland
buy Furazolidone online c o d
pharmacies carrying generic Furazolidone in NJ Frenchtown
cheapest Furazolidone free shipping at Lymington
Furazolidone generic online cheap in Cookstown
fda approved Furazolidone
best buy Furazolidone generic name
Furazolidone online sales co uk
Furazolidone online mail in Lurgan
Furazolidone discount order in MT
buy cheap cod online Furazolidone at Greensboro
is there a generic Furazolidone in Blantyre
buy Furazolidone tablet no doctors
buy online Furazolidone direct Bradford
Order Online Rx Furazolidone Without
cod Furazolidone for saturday at Deltona
order Furazolidone at Illinois
where to buy Furazolidone Elizabeth
Order No Perscription Furazolidone
buy cod Furazolidone online tablet saturday shipping
how do you get Furazolidone cheap buy
online pharmacies that accept cod for Furazolidone in NV Mc Gill
non generic Furazolidone no prescription Toulouse
purchase Furazolidone pharmacy rx on line at Washington Anatone
buy cod Furazolidone defenac drug without prescription
meds generic Furazolidone at Montana Ennis
mastercard Furazolidone in Bamburgh
Order Furazolidone Cheap No Prescription
get Furazolidone in internet discount free shipping at Kidwelly
Furazolidone prescrition online
buy Furazolidone search results online pharmacy in Kilwinning
Furazolidone rx pharmacy
Cheapest Furazolidone Online Doctors
best price for generic Furazolidone online overnight shipping in Hawkshead
Buy Generic Furazolidone No Prescription
purchase Furazolidone rx on line at AL Chancellor
get Furazolidone online visa overnight at Irvine
no prescription Furazolidone pharmaceutical no doctors in Hunstanton
Furazolidone in internet coupon fast at Hythe
generic Furazolidone compare prices generic online without prescription Hawaii
Furazolidone no prescription cod Raleigh
Furazolidone online shopping
purchase Furazolidone in internet discount
Furazolidone by prescription only in NM Cubero
Furazolidone in internet saturday shipping at Alabama Frisco City
Furazolidone in internet discount priority mail at Arizona Fort Apache
buy Furazolidone no prescription online doctor at Houston


text:
Match Report
El Matador delivers Paris!
Published at
At the end of 120 fiercely competitive minutes against Saint-Etienne, Paris emerged triumphant in the final seconds. A wonderful brace frm Edinson Cavani knocked out the defending champions and sent Paris into the quarter-finals, where they will meet Bordeaux at the Stade Chaban-Delmas.


text:
Rosemary Laskos, 91 of Rootstown, passed away Saturday, August 30, 2014 at Bonnie's Home Health Care in Rootstown. She was born August 29, 1923 in Akron, Ohio to the late John and Elizabeth (Havrilla) Halaiko. Mrs. Laskos was a lifelong resident of Rootstown and was a member of the Immaculate Conception Church in Ravenna.
Survivors include her children Stanley (Janet) Laskos, John (Char) Laskos, Susie Mathia, Dan (Sue) Laskos, 12 grandchildren and 17 great grandchildren with two on the way. In addition to her parents, she was preceded in death by her husband Stanley Laskos, Sr. in August of 2000, two brothers and two sisters. Private family services will be held at St. Mary Cemetery Ravenna, Ohio. The family asks that in lieu of flowers memorial donations may be made to Bonnie's Home Healthcare, Roses Rescue in Rootstown or the APL of Portage County. Condolences and memories may be shared with the family at www.sscfuneralhomes.com. Funeral arrangements entrusted to Shorts Spicer Crislip Funeral Homes Ravenna Chapel.
(Shorts-Spicer-Crislip 330-296-6858, RC 9-4-14)
So sorry to hear of Rosie's passing, nothing but pleasant memories of her! Love to all, Mike and Trish Petrus
Dear Stan, Janet, John, Char, Susie, John, Dan and Susan, and Family,
We send our most sincere sympathy to all of you in the loss of your Dear Mother. Aunt Rosie was a wonderful, selfless person, and the example of her life of giving means so very much to us too.
You are all in our thoughts and prayers.
Mike, Janie, Khrista, Olivia, Mike, Kristan and Mia Halaiko and Jordan Achtermann


text:
Welcome to E-Books Directory
This is a freely downloadable e-book.
Pregnancy Thrombophilia: The Unsuspected Risk
Read this book online or download it here for free
Custom Search
Pregnancy Thrombophilia: The Unsuspected Risk
by Petar Ivanov (ed.)
Publisher: InTech 2013
Number of pages: 158
Learn the recent statements concerning the impact and management of mother-fetal thrombophilia, the achievement necessary for gestation complication prevention and realizing a successful pregnancy valuation. This volume encompasses complete many-sides aspects of thrombophilic conditions during pregnancy.
More Sites Like This
|Science Books Online
|Books Fairy
|Maths e-Books
|Programming Books


text:
Normally these kind of things happen in school. do you rem any of you?
Follow me on Facebook, Twitter and RSS
Previous post: B-Boys breakdance at super slow motion
Next post: Halloween iPad Magic
Hello, there!We are building a free shopping app that will help you get discounts on the products you like. You will be able to request a discount for any product you like, whether you found it online or in your feed added by another user. Drop your e-mail to receive an early invite!
Follow buZzhunt to get your daily dose of fun!
Interested in advertising opportunities? Send an email.
Disclosure | Privacy Policy | Contact | Advertise | Copyright © 2008–2017


text:
3732 VINTAGE EAST ST N Park City, UT 84098
Hi, Blueroof 360.
My name is
and I have a question about 3732 VINTAGE EAST ST N Park City
You can respond by either emailing me at
or call during
My Question Is:
Estimated Monthly Payment$5,051
- Photos
- Location
- Questions
- Share
- Virtual Tour
- Mortgage Calculator
- Status: Active
Listing courtesy of KW Park City Keller Williams Real Estate
Vail Resorts has linked two of North America's greatest ski areas – creating the largest resort in the United States with 7,300 acres of skiable terrain. Now, you can be right in the center of the Village with this beautiful four bedroom, five bath ski-in, ski-out home. Large floor plan with vaulted ceilings, gourmet kitchen, designer finishes makes entertaining, living, and lounging so comfortable in this spacious home. Total of four bedrooms (including a master on the main floor and a large bunk room which sleeps 8), five baths, two car attached garage, heated driveway, radiant floors, and large mudroom for easy 'click in and out' of your ski boots after skiing straight into your new home from skiing all day! Then go to the Village for so many restaurant options or shopping! Try The Farm, 'Utah's Top 10' restaurants located in Canyons Village offers fresh, farm to table ingredients along with an award winning wine list to accompany. In the morning, fuel the day with coffee and a breakfast burrito from Murdock's Café. When the weather warms, try lunch at Red Tail Grill with their outdoor deck overlooking the ski beach. Golf at the Canyons Golf Course which winds through 97 acres in the heart of the Canyons Resort footprint, featuring over 550 feet of elevation change with spectacular views of the Wasatch and Uinta Mountains and surrounding valleys. The 18 hole, 6,000 yard, par-69 course, designed by renowned course architects Gene Bates and Casey Bates, offers 18 holes of challenging and enjoyable golf characterized by memorable shots with dramatic views. The course begins near the Orange Bubble Express lift and heads up the Willow Draw area before winding its way around the Waldorf Astoria Hotel and down by highway 224 and back up towards the Orange Bubble Express.
Interior Features Include:
Bath: Master, Bath: Sep. Tub/Shower, Central Vacuum, Closet: Walk-In, Dishwasher: Built-In, Disposal, Great Room, Oven: Gas, Range: Gas, Vaulted Ceilings, Granite Countertops
Basement None/Crawl Space
Fireplaces 2
Heating: Forced Air
Floor Type: Carpet, Hardwood, Tile, Slate, Travertine
None/Crawl Space
Exterior Features Include:
Deck: Covered, Double Pane Windows, Entry (Foyer), Outdoor Lighting, Patio: Covered, Sliding Glass Doors
Acreage: 0.0100 Acres
Lot: Road: Paved, Sprinkler: Auto-Full, Terrain: Grad Slope, View: Mountain, View: Valley, Drip Irrigation: Auto-Full
Landscape Landscaping: Full, Pines
Landscape: Full Landscaping, Pines
Roof: Asphalt Shingles
Exterior: Asphalt Shingles, Stone
Driveway Concrete
Garage Capacity: 2
Carport Capacity: 2
Other Features Include:
Subdivision: VINTAGE ON THE STRND
Inclusions: Ceiling Fan, Dryer, Fireplace Equipment, Microwave, Range Hood, Refrigerator, Washer, Water Softener: Own, Window Coverings
Amenities: Home Warranty
Water: Culinary
Sewer: Connected, Public
Utilities Gas: Connected, Power: Connected, Sewer: Connected, Sewer: Public, Water: Connected
Accessibility 32' Wide Doorways
Storage Garage
Taxes 10696
School District: Park City
Information deemed reliable but not guaranteed accurate. Buyer to verify all information.The multiple listing information is provided by Wasatch Front Regional Multiple Listing Service, Inc. from a copyrighted compilation of listings. The compilation of listings and each individual listing are © 2014 Wasatch Front Regional Multiple Listing Service, Inc., All Rights Reserved. The information provided is for consumers, personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.


text: MELVILLE, N.Y., July 10, 2013 /PRNewswire/ -- Henry Schein, Inc. (NASDAQ: HSIC), the world's largest provider of health care products and services to office-based dental, medical and animal health practitioners, announced today that it has divested its investment in a dental wholesale distributor in the Middle East. The investment was an unprofitable, noncontrolling interest in an entity that primarily served as an importer that distributed products largely to other distributors. The divestiture is expected to generate a one-time charge in the range of $11 million to $13 million, or 13 cents to 15 cents per diluted share, in the third quarter of 2013. Henry Schein will show third quarter earnings results excluding the impact of this loss in order to provide more meaningful year-on-year comparisons of the Company`s core financial performance. " Henry Schein's strategic plan is focused on growing our presence as the leading global distributor of products and related value added services in the market segments we serve," said Stanley M. Bergman, Chairman of the Board and Chief Executive Officer of Henry Schein. "As part of that plan, we have elected to divest our interest in this non-core holding to further align our investments targeting our primary customer base, the office-based practitioner." About Henry Schein, Inc. Henry Schein, Inc. is the world's largest provider of health care products and services to office-based dental, medical and animal health practitioners. The Company also serves dental laboratories, government and institutional health care clinics, and other alternate care sites. A Fortune 500® Company and a member of the NASDAQ 100® Index, Henry Schein employs more than 15,500 Team Schein Members and serves more than 775,000 customers. The Company offers a comprehensive selection of products and services, including value-added solutions for operating efficient practices and delivering high-quality care. Henry Schein operates through a centralized and automated distribution network, with a selection of more than 96,000 branded products and Henry Schein private-brand products in stock, as well as more than 110,000 additional products available as special-order items. The Company also offers its customers exclusive, innovative technology solutions, including practice management software and e-commerce solutions, as well as a broad range of financial services.


text:
Creamy Bites with calcium citrate
Adequate calcium and vitamin D as part of a healthy diet, along with physical activity, may reduce the risk of osteoporosis later in life. It is important to nourish bones with essential calcium so they grow strong and stay strong for a lifetime. At any age, calcium and vitamin D are essential for good bone health.
Creamy Bites supplies the absorbable calcium and vitamin D3 needed to build and maintain strong bones that support an active healthy lifestyle. Creamy Bites comes in 2 delicious flavors to satisfy even the pickiest eater – choose between delicious lemon cream or chocolate fudge.
With no more than 40 calories per bite, Creamy Bites is a sensible way to supplement your diet with a tasty snack – and bridge the gap between the calcium you get and the calcium you need. Highly absorbable calcium citrate makes up the difference in a convenient snack that is appealing to children and adults.
Creamy Bites are a tasty snack in a convenient pack that can be enjoyed any time, with or without food
"With good habits and medical attention when needed,
we can have strong bones throughout our lives."
Surgeon General's Report on Bone Health and Osteoporosis
Each piece contains 500 mg of calcium citrate and 400 IU of vitamin D3. The highly absorbable formulation of Creamy Bites ensures that your family gets the health benefits from supplemental calcium. Calcium citrate is proven to be gentle on the digestive system so, unlike other calcium supplements, it can be taken with or without food – and without the gas or bloating associated with other forms of calcium. Help your family maintain an active and vital lifestyle.
- Recker RR. Calcium absorption and achlorhydria. N Engl J Med. 1985;313(2):73.


text:
A few weeks ago I had the strangest starting problem on my 2002 WRX. The car behaves like I am trying to start it without pushing the clutch pedal. No reaction at all when turning the key, no starter click at all. I thought it may have been an alarm or starter kill issue, but I can bump start the car just fine. The fuel pump comes on fine. After a few days of me and my friends checking fuses, battery cables, the clutch pedal safety switch, etc, it all of a sudden randomly starts just fine, without a single problem for 3 weeks.
Last night after driving all day, the same problem randomly came back. Had to push start to get home, and now in the driveway it still won't start.
I'm new to Subarus so I was not sure if there was a model-specific sensor or switch or fuse to check... I've been searching the forums and can't find anything so far.


text:
Revlon has scooped up Emma Stone and Olivia Wilde, making them the latest actresses to land a major beauty campaign. As Global Brand Ambassadors for the makeup behemoth, Stone and Wilde's first ad campaigns will be tied to the launch of new color cosmetics and nail enamel products set to premiere in early 2012. Between the two actresses, they have six major feature films in 2011, including Stone's star turn in The Help, which is out today.
Sign up for Lifeline Live e-mail alerts