text:
Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination, Volume 600
1st Edition
Table of Contents
1. DSB processing in yeast
Loraine Symington
2. Purification of DNA end resection enzymes
Petr Ceijka
3. Biochemistry of DNA end resection
Petr Ceijka
4. Visualization of telomere movement and interchromosomal homology searches in ALT
Roger Greenberg
5. Pre-steady state kinetic methods for investigating the DNA exonuclease activity of Mre11
Scott Nelson
6. Production of large quantities of human RAD51
Maria Spies
7. Determining the RAD51 nucleoprotein filamentous structure and mechanism by CryoEM
Hong-Wei Wang
8. Single-molecule TIRF analysis of human RAD51 nucleation
Maria Spies
9. TIRF-based single-molecule detection of the RecA presynaptic filament dynamics
Sung Hyun Kim
10. Archaeal (Sulpholobus) RadA and its paralogs
Cynthia Haseltine
11. 4-strand DNA strand exchange
Alexander Mazin
12. Purification and biochemistry of DMC1 recombinase
Doug Bishop
13. Single-molecule TIRF analysis of yeast Rad51 nucleoprotein disassembly by helicases
Sua Myong
14. The recombination mediator BRCA2: architectural plasticity of recombination intermediates revealed by single molecule imaging (SFM/TIRF)
Claire Wyman
15. Visualisation and quantitation of BRCA2/RAD51 dynamics in cells
Roland Kanaar
16. RPA - DNA curtains
Eric Greene
17. Single-molecule studies of ssDNA binding proteins
Taekjip Ha
18. BRCA2 as recombination mediator
Aura Carreira
19. Ustilago maydis Brh2 as a model for human BRCA2
Bill Holloman
20. Purification and analysis of holiday junction resolvases
Stephen West
21. Structural analysis of HJ resolving enzyme GEN1
David Lilley
22. The preparation of four-stranded recombination intermediates for use in the HJ resolution reactions
Stephen West
Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination, Volume 600, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.
Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts.
Key Features
- Contributions by the leading experts in the field of DNA repair, recombination, replication and genome stability
- Documents cutting edge methods
Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists
- No. of pages:
- 412
- Copyright:
- © Academic Press 2018
- Published:
- 1st March 2018
- Imprint:
- Academic Press
- Hardcover ISBN:
- 9780128144299
Praise for the Series:
"Should be on the shelves of all libraries in the world as a whole collection." --Chemistry in Industry
"The work most often consulted in the lab." --Enzymologia
"The Methods in Enzymology series represents the gold-standard." --Neuroscience
Ratings and Reviews
About the Serial Volume Editors
Maria Spies Serial Volume Editor
Graduate of Peter the Great St. Petersburg Polytechnic University, Russia (1996 MS diploma with honors (equivalent of cum laude) in physics/biophysics) and Osaka University, Japan (2000 PhD in biological sciences), Dr. Maria Spies is an Associate Professor of Biochemistry at the University of Iowa Carver College of Medicine. Spies' research career has been focused on deciphering the intricate choreography of the molecular machines orchestrating the central steps in the homology directed DNA repair. Her doctoral research supported by the Japanese Government (MONBUSHO) Graduate Scholarship provided the first detailed biochemical characterization of archaeal recombinase RadA. In her postdoctoral work with Dr. Steve Kowalczykowski (UC Davis) supported by the American Cancer Society, Spies reconstituted at the single-molecule level the initial steps of bacterial recombination and helped to explain how this process is regulated. Spies' laboratory at the University of Iowa emphasizes the molecular machinery of homologous recombination, how it is integrated into DNA replication, repair and recombination (the 3Rs of genome stability), and how it is misappropriated in the molecular pathways that process stalled DNA replication events and DNA breaks through highly mutagenic, genome destabilizing mechanisms. Her goal is to understand, reconstitute and manipulate an elaborate network of DNA recombination, replication and repair, and to harness this understanding for anticancer drug discovery. The Spies lab utilizes a broad spectrum of techniques from biochemical reconstitutions of the key biochemical reactions in DNA recombination, repair and replication, to structural and single-molecule analyses of the proteins and enzymes coordinating these reactions, to combined HTS/CADD campaigns targeting human DNA repair proteins. Work in Spies Lab has been funded by the American Cancer Society (ACS), Howard Hughes Medical Institute (HHMI), and is currently supported by the National Institutes of Health (NIH). She received several prestigious awards including HHMI Early Career Scientist Award and Margaret Oakley Dayhoff Award in Biophysics. She serves on the editorial board of the Journal of Biological Chemistry, and as an academic editor of the journal Plos-ONE. She is a permanent member and a chair of the American Cancer Society "DNA mechanisms in cancer" review panel.
Affiliations and Expertise
Carver College of Medicine, University of Iowa, USA
Anna Malkova Serial Volume Editor
Graduate of the St. Petersburg State University, Russia (1987 MS diploma with honors (equivalent of cum laude) in Genetics and 1993 Ph.D. in Genetics), Dr. Anna Malkova is an Associate Professor of Biology Department at the University of Iowa College of Liberal Arts and Sciences. Malkova's research is focused on DNA repair mechanisms. She investigates the repair of double-strand DNA breaks (DSBs), the most lethal type of DNA lesions. Using a dependable and powerful model system in yeast, where a single DSB is initiated by a site-specific HO endonuclease, she successfully demonstrated that imprecise or faulty repair of DSBs leads to structural genomic variations including mutations, copy number variations (CNVs), and chromosomal rearrangements similar to those that cause genetic diseases and cancer in humans. She has a longstanding interest in break-induced replication (BIR), a DSB repair pathway that repairs so-called one-ended DNA breaks, similar to those produced at eroded telomeres and by collapsed replication forks. In her postdoctoral work with Dr. James Haber (Brandeis University), she was among the first who identified this mechanism in eukaryotes. Studies in Malkova's laboratory provided important insights into the mechanism of BIR, which was found to be fundamentally different from the mechanism of S-phase DNA replication. In particular, it was discovered that BIR is carried out by a migrating bubble rather than by a replication fork, and leads to conservative inheritance of newly synthesized DNA. This unusual molecular mechanism explained bursts of genetic instability that were observed in association with BIR, and that were similar to those associated with cancer and other diseases rooted in genetic instability. Work in Malkova's lab is supported by the National Institutes of Health (NIH). Anna serves as a member to the Cancer Etiology study section of NIH/NCI.
Affiliations and Expertise
Department of Biology, University of Iowa, Iowa City, Iowa, USA


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As a Christmas present to my pops, Marconi took the menfolk on a fishing trip the day after Christmas.
Dad and bro.
My first catch. I didn't get any keepers. Couldn't figure out how to snag them when I felt a couple bites. Sounds like my love life. Zing!
Crack a cold one Chris. You deserve it.
Nothin' like the golden hour on the open seas.
We may not be the best at catching fish, but we look damn good doing it.

subset: commoncrawl


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"A video game comic and blog that would have been awesome and relevant 10 years ago. Maybe." -Famous Website
september 28, 2012
Let's talk about the Lunar Series by Game Arts! =D Discovering Lunar for the first time was a very impressionable time for me. I was in a huge RPG high since I just started playing console RPG's a few years earlier. It was around some time after Final Fantasy 6's release that I went over to a friend's house and was introduced to the Sega CD for which my friend had Lunar and Lunar Eternal Blue.
I was completely captivated by Lunar: The Silver Star's visual charm, the amazing quality of the synthesized music, and the fact that there was actual voice acting and cinematics! =D I admit that the first game felt like it didn't have much meat and the voice acting was kinda corny, but it was the good kind of corny that makes you smile and permanently imprints itself into your memory. XD
Though the battle system can be considered really simple to today's standards, it was definitely something different and rather charming! I loved how the battles actually had both your characters and your enemies fully animated and running around on the battle field. There was a stat that determined how far each character can walk and a stat for the number of attacks they can do; if they ran out of steps before they reached an enemy, then they'd use up one of their attack turns as a movement turn. Skills also had specific ranges such as only hitting enemies in a horizontal line adjacent to that character or all enemies surrounding a targeted enemy. It was a very simple system, but it added a lot of fun with a bit of strategy.
One funny thing about the system was that the spell list shuffled upon you using a skill, putting the most recent skill you used at the top of the character's skill list. There was no tool tip telling you what each skill did either so you had to resort to experimentation or research if you forgot what a skill did. XD Also, the game kind of ended in a weird way too by having no real conclusion after you saved the world. ^^; It was okay though because it was fun. XD I admit the game was rather easy too, but I kinda consider the very first Lunar to be more of the stepping stone to ready you for Lunar Eternal Blue, a real kick-ass sequel! XD
Lunar Eternal Blue's story takes place a thousand years after the first game. You might think that a sequel taking place so long afterwards wouldn't have much relevance to its precursor but it surprisingly does; a lot in fact! XD It was also very exciting for me to play two games with a continuous world for the first time! =D
Game Arts really stepped up their game! The base concepts for world romping and battle mechanics were carried over, but everything else was improved upon dramatically; it's almost incomparable. Some very notable changes other than it's gorgeous art direction were that enemies now had specific weaknesses and strengths towards certain attacks, all characters were associated to a type of element or attack type, the cinematics had real animation (unlike the first Lunar in which "cinematics" were mostly static images of characters with flapping mouths), all characters had eight skills -four for each category that were represented by really awesome looking icons on the skill lists, and a long epic engrossing story including an important epilogue to tie everything up.
Lunar Eternal Blue really blew my mind back then leaving me a huge fan of the series! The only real issue I had with the game was that after winning battles, you gained magic experience points. You were meant to use these points to upgrade skills, changing your single target heal to a stronger version for example, and every subsequent version of that spell costs more magic experience than the previous. Your party also shared the pool of magic experience points, saving your game costs the same points AND every subsequent save you make will cost more than your last.
This compelled me to want to only upgrade spells if I was absolutely sure I needed to and to play for as many hours as I can in a single sitting. Dying in a battle was an aggravating feeling, but I think there were temporary respawn points in case that happened. It was definitely not a fun experience having to keep that in the back of my mind. Later I discovered that the magic experience system was implemented by the American publishers Working Designs and that spells naturally upgraded on their own in the original Japanese version. I didn't see any point in the system's implementation, especially for the simple act of saving your game. Since then, I've been had some iffy feelings about Working Designs which I'll get to talking about in a bit. o_<
In 1996, Game Arts released a complete remake of Lunar: The Silver Star, Lunar: The Silver Star Story. It was one of the main reasons why I got a Sega Saturn! XD It was an amazing remake; everything was remade and improved upon! It implemented all the awesome mechanics and design choices made in Lunar Eternal Blue and strengthened its weaknesses to make a meaty, epic game! =D I was kind of disappointed at first that all of the music was completely redone too, but I grew to love the new music too. =) The only things that I think are kind of a shame about the game are that the cinematic video quality suffers due to technological limitations at the time of its release, video compression problems and that after a while, every boss fight can be dealt with by repeating the same strategy.
A remake of Lunar Eternal Blue came out a few years later called Lunar 2 Eternal Blue. Like Lunar:SSS, it was a complete remake (except for its music)! I admit that even though it was an awesome remake, there are still a number of things I like more in the original. For one, I loved the old menu style and design that was reused for Lunar:SSS; it was clean, simple, and felt a lot less "closed in." The second thing I was really disappointed in was that they changed how a lot of the skills look and function. I read that the creators were experimenting with new visual effects such as zoom-ins for certain attacks to increase its visual impact, but I felt the old fashioned "flash-on-impact" effects were better. There were a number of small factors that I felt were very strong and cool in the old one that were taken out; I'd cap on them, but I gotta wrap this up soon. It really feels like though the original Sega CD and the remake have so many similarities, they are rather different entities. If you're a big Lunar fan, I think I'd recommend taking a look at the Sega CD version too if you have the time.
Since I was such a passionate Lunar fan, I looked into other works published by Working Designs and though I admit they do great work and I like the selection of games they chose to localize, I couldn't help but feel a strong dislike for a how they did some things. One thing I noticed a while back that I hated was that before the release of Lunar Silver Star Story Complete (the remake of Lunar for the Playstation), All of their previous games' opening company credits were taken out and replaced with their own. As a kid discovering Lunar, I had to make an effort searching for what company actually made the game, not just published it. It gave the impression that they were taking credit for making the game; even their old website in the mid 90's said "...the games we make..." As a passionate fan and a purist at the time, I couldn't stand how they felt the need to make pop culture references in games. From what I remember, I think there's a Clinton joke in a library in the original Lunar 2 for Sega CD and in Lunar:SSSC, there's a kid saying something about wanting to eat Wheaties to grow strong (or something). I know it doesn't really matter, but like I said, it was a time when I was a serious localization purist. ^^;
Since their publications of the Lunar remakes for the PSX, they felt the need to make big changes to games they've published. I admit that they probably did a good job at making Alundra harder in their version, but it really riles me up that they made system mechanic and difficulty changes to games like Silhouette Mirage, Elemental Gearbolt, and Arc the Lad Collection. I seriously feel that Elemental Gearbolt is impossible to beat for any non super pro player. If Working Designs felt these games were too easy, at least leave their changes as a selectable option!
september 28, 2012


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1902. 'And Abram hearkened to Sarai's voice' means it could not have been achieved in any other way. This becomes clear from the train of thought in the internal sense and from the necessity that the human rational can be born in this and no other way. If man were not steeped in any hereditary evil, the rational would be born straightaway from the marriage of the celestial things belonging to the internal man with the spiritual things belonging to the same; and through the rational the faculty of knowing would be born. This would mean that on entering the world a person would possess straightaway within himself fully-formed faculties of reason and of knowing, for this would all be in accordance with the order that belongs to influx. This may be deduced from the fact that all animals without exception are born into a fully-formed faculty of knowing what they need and what is suitable for them in the way of food, safety, habitat, and producing offspring, because their inborn nature is in accordance with order. For what other reason is man born without the same faculties than that in his case order has been destroyed - for he alone is born without any knowledge?
[2] That which causes him to be born without any knowledge is hereditary evil received from his father and from his mother. Because of that evil all his faculties are turned in a contrary direction insofar as goods and truths are concerned, so that the latter are not able through an immediate influx of celestial and spiritual things from the Lord to be translated into correspondent forms. This is the reason why man's rational has to be formed in an entirely different manner or way, that is to say, by means of facts and cognitions entering in through the senses, and so by the external route, thus by what is a reversal of order. In this way, miraculously so, a person is made rational by the Lord. This is described by 'going in to the servant-girl', which means the joining of the internal man to the exterior man, and by the statement that 'Abram hearkened to the voice of Sarai', which means that it could not have been achieved in any other way.
[3] Because the Lord was born as any other is born and had a heredity from the mother, He was like any other in this respect also, the purpose being that through the conflicts brought about by temptations and through victories He might restore all things to order. His Rational as well therefore was conceived and born as it is with any other, yet with the difference that the Divine, or Jehovah - and so the life belonging to love towards the whole human race, on whose behalf and for whose salvation He fought in all His temptations - resided in every single thing that was His inmostly.


text:
Three Maidens
first edition
1930 · New York
by PHILLPOTTS, Eden
New York: Smith, 1930. Good. First edition. Good/p. Pages evenly brown. Corners slightly bent. Spine faded. Edges of spine bumped. Edges of dustwrapper worn and torn. Light water stain on rear dustwrapper. Small red stain on rear dustwrapper. Dustwrapper shelf rubbed. Please Note: This book has been transferred to Between the Covers from another database and might not be described to our usual standards. Please inquire for more detailed condition information. (Inventory #: 243913)


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1 quart buttermilk
- 1/2 cup chopped shallots
- A pair of tablespoons chopped garlic
- A pair of tablespoons kosher salt
- 2 tablespoons sugar
- A single tablespoon ground cumin
- A person teaspoon pepper
- 7 chicken thighs (a couple of 1/2 single pound. total)
- Half-dozen chicken drumsticks (regarding A single 3/4 pound. total)
How to make Grilled Buttermilk Chicken
- Inside of a large tank, mixture buttermilk, shallots, garlic, salt, sugar, cumin, in addition to pepper.
- Rinse chicken thighs and also drumsticks and terry dry up. Cut off surplus fat. Submerge chicken portions within buttermilk brine. Protect along with evening chill for about 4 several hours, and also about Day (find information).
- Lift chicken out of brine; toss brine. Wash surplus out of chicken having paper towels.
- Set chicken pieces on a grill around carrier hot coals or perhaps carrier warm over a propane gas grill (you possibly can store your hand with barbecue grill amount solely Four to five a few moments); near lid on grill. Cook dinner, converting often, until eventually browned on facets and no for a longer period green at the bone (reduce to evaluate), 20 to 30 mins. Serve hot or cold.
Grilled Buttermilk Chicken is ready to serve.


text:
Eater Miami Names Barton G. The Restaurant's Cotton Candy One of the City's Best Desserts
August 2012
August 2012
Frommer's called it "reminiscent of drag diva Dame Edna's hair." A signature dessert at Barton G. The Restaurant, the Big Top Cotton Candy symbolizes everything exuberant, theatrical and witty about the menu. And now it has been named one of the city's nine best desserts by Eater Miami. An immense cloud of evanescent sweetness served with chocolate pretzels and white-, dark- and milk-chocolate-covered popcorn balls, this Cotton Candy is the ideal combination of childhood memory and adult indulgence. Visit bartongrestaurant.com to learn more.
TAGS: Barton G. Restaurant, cotton candy, Dessert, Eater Miami, Vault magazine


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- News
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- Browse
Madden NFL 13 PS3, Xbox 360 hikes top 15 pre-order sales
By News Division On July 20, 2012 · In News, Playstation 3, Retail, Systems, Xbox 360
EA Inc.'s Madden NFL 13 for Sony Corp.'s Playstation 3 and Microsoft Corp.'s Xbox 360 ranked in the top 15 pre-order sales at GameStop Corp.'s online division due to strong demand.
This week, the Madden NFL 13 Xbox 360 SKU ranked as the No. 13 best-selling pre-order product at GameStop.com.
The PS3 SKU ranked at No. 15 in the same period.
Madden NFL 13, to be sold Aug. 28, will include a new Madden Ultimate Team Mode to collect virtual cards with new content and updates that mirror current NFL events for the year.
The final game is said to feature a redesigned passing game and all new read-and-react defensive AI system.
This week, customers who pre-order Madden NFL 13 will receive NFL legends Joe Gibbs and Lawrence Taylor for use in Madden Ultimate Team and the Connected Careers mode.
Follow us on Twitter @PunchJump, @WeLoveHotDeals, @PreOrderBonus, @Punchissimo, and visit us at Facebook and Google+.
Comments are closed.


text:
Hameed Ali: Customs boss dares Senate, says 'no' to Wednesday appearance
Comptroller-General of Nigeria customs Service, Col. Hameed Ali (rtd.), has informed the Senate that he would not appear before the lawmakers on Wednesday, March 15.
The Customs CG, in a letter to the Upper Chamber said he could appear before the lawmakers on the said date as it coincided with the routine management of the service.
The Customs boss requested that the Senate fix another date for his appearance.
Ali's letter requesting for another date for his appearance was read to lawmakers at the plenary, on Tuesday.
The letter was signed by an Assistant Comptroller-General.
It was gathered that members of the Red Chanber lampooned Ali for relegating the Senate and for failing to personally sign the letter.
Elsewhere today, the senate agreed to hold confirmation hearing for Magu on Wednesday
The senate will hold a confirmation hearing for Ibrahim Magu, acting chairman of the Economic and Financial Crimes Commission (EFCC), on Wednesday.
Senate President Bukola Saraki announced this on Tuesday.
This is coming a few weeks after President Muhammadu Buhari asked the senate to reconsider its decision to reject the appointment of Magu as EFCC chairman.
Vice-President Yemi Osinbajo had sent a letter requesting Magu's confirmation to the senate while the president was on vacation in the United Kingdom.
On January 24, Saraki read the letter after the upper legislative chamber resumed from a closed session that lasted about 80 minutes.
On December 15, 2016, the senate rejected the appointment of Magu as EFCC chairman, citing a security report from the department of state services (DSS).
In the report, Magu was accused of living in a house paid for by a "corrupt" businessman. He was also accused of extorting money — through a proxy — from suspects.
Following this, the president directed Abubakar Malami, attorney-general of the federation, to investigate the allegations.
Malami submitted his report at the end of the assignment.
However, the details of the investigation were not revealed in the president's letter to the senate.
Also, the president did not say why the rejection of Magu's appointment should be reconsidered in view of the allegations.
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CalCOFI Reports Vol 40, 1999 (Complete pdf; individual pdf links below)
Symposium: A CONTINUING DIALOG ON NO-TAKE RESERVES FOR RESOURCE MANAGEMENT
- The State of the California Current in 1998-1999: Transition to Cool-Water Conditions. Thomas L. Hayward, Tim R. Baumgartner, David M. Checkley, Reginaldo Durazo, Gilbert Gaxiola-Castro, K. David Hyrenbach, Arnold W Mantyla, Michael M. Mullin, Tom Murphree, Franklin B. Schwing, Paul E. Smith, and Mia J. Tegner
- Report of the CalCOFI Committee
- Review of Some California Fisheries for 1998: Pacific Sardine, Pacific Mackerel, Pacific Herring, Market Squid, Sea Urchin, Groundfishes, Swordfish, Sharks, Nearshore Finfishes, Abalone, Dungeness Crab, Prawn, Ocean Salmon, White Seabass, and Recreational
- Index to "Review of Some California Fisheries," 1977-1998
- Brown Shrimp Fishery in the Gulf of California. Enrique Morales-Bojdrquez andjuana Ldpez-Martinez
- Publications
II. Symposium of the CalCOFI Conference, 1998
- Analyzing California's Marine Managed Areas: Existing Classifications and Options for the Future. Brian E. Baird, Melissa A . Miller-Henson, and Brice X. Semmens
- Marine Protected Areas as a Precautionary Approach to Management. Mark H. Carr and Peter T. Raimondi
- Marine Reserves for Fisheries Management: Why Not. Richard Parrish
- Marine Reserves and Management of the Northern California Red Sea Urchin Fishery. Louis W Botsford, Lance E. Morgan, Dale R. Lockwood, and James E. Wilen
- Spatial and Temporal Genetic Patchiness in Marine Populations and Their Implications for Fisheries Management. Ralph J Larson and Richard M. Julian
- Human Visitation and the Frequency and Potential Effects of Collecting on Rocky Intertidal Populations in Southern California Marine Reserves. Steven N. Murray, Eri Gibson Denis, Janine S. Kido, and Jayson R. Smith
- Economic and Management Implications of No-Take Reserves: An Application to Sebastes Rockfish in California. Cynthia J. Thornson
- Social Considerations for Marine Resource Management: Evidence from Big Creek Ecological Reserve
. Caroline Pomeroy
III. Scientific Contributions
- Fine-Scale Distributions of Planktonic Fish Eggs in the Vicinities of Big Sycamore Canyon and Vandenberg Ecological Reserves, and Anacapa and SanMiguelIslands,California. William Watson, Richard L. Charter, H. Geoffrey Moser, Russell D. Vetter, David A. Ambrose, Sharon R. Charter, Larry L. Robertson, Elaine M. Sandknop, Eric A. Lynn, and Jason Stannard
- Key Species in the Pelagic Copepod Community Structure on the West Coast of Baja California,Mexico. Sergio Hernandez-Trujillo
- Variation in Fat Content of Northern Anchovy (Engraulis mordax) in Relation to the Baja California Environment. Walterio Garcia-Franco, Ricardo Vidal- Talamantes, Alfredo Cota- Villavicencio, Jose Ramon- Corrales, and Irene Prieto-Montalvo
- Bioeconomics of the Pacific Sardine (Sardinops sagax) Fishery in the Gulf of California, Mexico. Antonio de Anda-Montanez and Juan C. Seijo
- Length-Based Growth Estimates for Pacific Sardine (Sardinops sagax) in the Gulf of California,Mexico. Antonio de Anda-Montanez, Francisco Arreguin-Sanchez, and Susana Martinez-Aguilar
- Variability of Sardine Catch as Related to Enrichment, Concentration, and Retention Processes in the Central Gulf of California. Salvador E. Lluch-Cota, Daniel B. Lluch-Cota, Daniel Lluch-Belda, Manuel 0. Nevarez-Martinez, Alejandro Pares-Sierra, and Sergio Hernandez-Vazquez
- Age and Growth of Market Squid (Loligo opalescens) off California during 1998. John Butler, Daniel Fuller, and Marci Yaremko
- Market Squid (Loligo opalescens) in the Diet of California Sea Lions (Zalophus californianus) in Southern California (1981-1995). Mark S. Lowry and James V Carretta
January 1 to December 31, 1998
Cooperating Agencies: CALIFORNIA DEPARTMENT OF FISH AND GAME, UNlVERSlTY OF CALIFORNIA, SCRIPPS INSTITUTION OF OCEANOGRAPHY, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, NATIONAL MARINE FISHERIES SERVICE
CalCOFl COORDINATOR: George Hemingway
EDITOR: Julie Olfe
This report is not copyrighted, except where otherwise indicated, and may be reproduced in other publications provided credit is given to the California Cooperative Oceanic Fisheries Investigations and to the author(s). Inquiries concerning this report should be addressed to CalCOFl Coordinator, University of California, San Diego, Marine life Research Group, Scripps Institution of Oceanography, 9500 Gilman Drive, La Jolla, CA 92093-0227.
Doyle Hanan, Michael Mullin, Michael Tillman
Published October 1999, La Jolla, California
lSSN 0575-33 17


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Happy first day of December! I put up the Christmas tree in our apartment on Sunday night and did a little Christmas shopping so I really feel in the Christmas spirit. The past few months I've been sharing my favorites from all month long (from memories to television shows to cute shoes). November was a weird month because I was out of town for all but a week of it. I loved spending time in Calistoga and San Francisco to switch up my routine.
November Favorites
Parson & Teen Vogue Fashion Essentials Course| I recently finished the first unit of the Parsons & Teen Vogue Fashion Essentials course. The course is five units and is offered fully online. I signed up because I love fashion and I am always interested in learning more about the complex industry. So far the course has been a little repetitive (since I have taken fashion courses before) but I am enjoying it nonetheless. This week I am starting the second unit "Thinking Like a Designer". I am excited to see what the unit focuses on! If you've been considering the course and have any questions feel free to send them my way.
NaNoWriMo 2015| The month of November I participated in National Novel Writing Month. I came nowhere near to my goal of 50,000 words, however I did spend a good amount of time writing and found an engaging plot. My goal for December is to continue focusing on my novel despite the craziness of the holidays. If you've written a novel before I would love your tips for pushing through during busy times.
Thanksgiving Weekend| I spent this Thanksgiving with my Mom and her fiance's family. I am generally not a huge fan of Thanksgiving (I'm a vegetarian and not a huge fan of Thanksgiving food or hanging out with strangers) but really enjoyed the celebration this year. Friday night Jordan and I stayed at my Mom and her fiance's cabin near Mt.Rainier. The cabin sits on a beautiful property and doesn't have internet or cellphone service (which is actually really refreshing). Though we only stayed overnight I had a great time eating more Thanksgiving food and playing games with my family.
Tory Burch Tassel Bags| I picked up this bag at Nordstrom during the Thanksgiving weekend sale for 30% off. I was so excited; I've loved burgundy bags for the past year so getting my hands on such a cute piece was definitely exciting! Right now Tory Burch is carrying so many cute tasseled products from a tassel key ring, to a tasseled mini backpack, to a quirky needlepoint tasseled pillow. I also adore these Acorn Charm Smoking Slippers (they're not tasseled but they're still totally gorgeous for winter). Are you as crazy for Tory as I am?!
Quality time with my Siblings| While in Napa Valley for the last month I was able to spend quite a bit of time with my two youngest siblings Dylan (age 8) and Gigi (age 2). Dylan and Gigi are such little cuties. I love being a big sister and having siblings SO much younger than me is a lot of fun. Age eight is quite possibly my favorite age in the entire world. Dylan is so filled with imagination, energy and zest for life, while still maintaining optimism and sass. I am so grateful for the time I spent riding bikes, doing homework and playing at the park with my baby brother and sister.
Maybe in Another Life by Taylor Jenkins Reid| My goal for the month was to read three books and sadly I only read one, however the one I did read was incredibly compelling, I literally sat down and read Taylor Jenkins Reid's latest novel in one six hour sitting. Maybe in Another Life follows the story of Hannah, a cinnamon roll obsessed twenty-nine year old with no sense of purpose or direction. Feeling deflated after discovering she was having an affair with a married man, Hannah moves back to her hometown of Los Angeles to stay with her best friend and figure her life out. On her first night out in L.A. Hannah must make a choice to go home with her BFF or stay out with her old high school sweetheart. At this portion the book breaks into two story lines-what would happen if Hannah stayed with her ex and what would unfold if she left the bar with her friend. This light hearted girly read was intriguing and unpredictable, it really made me think about everything that could be in life. As someone who identifies with being indecisive this book really resonated with me. If you're looking for an quick read you won't be able to put down for Christmas break reading I highly recommend Maybe in Another Life.
San Francisco Adventures| One of the best perks about staying in Calistoga most of the month was its close proximity to San Francisco. For the amount of time I have spent in California I haven't spent nearly enough time in the Bay Area. San Francisco really stole my heart on this trip and passed Los Angeles on my list of best West Coast cities. I had such a great time wandering through the city alone, with Jordan and even with Caroline. Though I loved the shopping, the food and the fantastic bay views, my absolute favorite part of San Francisco is the architecture. What wouldn't I do for a cute $5 million 3 bedroom in Russian Hills? I should have been born a millionaire, I would be just darling at it (:
My December Wish List: Steve Madden Navy Booties,Kate Spade All in Good Taste,A Day with Marie Antoinette, Lace up Flats, Christmas Pajamas (like THESE or THESE) and for some reason I've been dying for a pair of sequin leggings (wouldn't they be the perfect touch for a holiday party?). What's on your personal wish list for December?
Do you have any favorite products, clothes, movies or memories from this month? I love to hear what you guys are loving!


text: Have my zmax for a few days now, would like to post my review; Metro version, paid 250 but got a 50 buck rebate, THIS PHONE IS INEXPENSIVE but has a better build feeling then the mega. First, I came off of the samsung mega, which I loved until the kitkat update, Kitkat is absolutely the worst android update I have ever tried on any phone, really bogged down the low end hardware of the mega,( which only has a dual core) After the kitkat "upgrade the boot loader is locked and I cannot find a sound and safe root Then I broke the screen, and replacing the screen was only a couple less then trying the zmax so zmax I got. The zmax has a smaller screen then the mega, and it's almost the same size overall, I can't gloss over that, if I could get an even bigger screen I would so that's one complaint in comparison to the mega, the bigger screen on the mega was the only reason i did not get the note The zmax also has kitkat and there is no root for the kat on this phone yet either, however the zmax is such a trimmed down bare bones version of android that there isn't much more I would do with root privilege, this phone has a quadcore, the mega is dual, zmax is MUCH faster then the mega running kitkat, and faster then mega was on the bean, programs snap to, close fast, the phone comes right up, on the mega the phone lagged for what seemed like seconds once I "upgraded" to kitkat. In addition, disabling a program in settings keeps it from loading at boot too so I don't really need root to get rid of what little bloat is on this phone. The speaker seems the same quality and volume as the mega, I know on the web they say it's a small speaker for a big phone but I don't notice a difference over the mega, that might be me though, don't trust me on that cuz I am not doing side by side db benchmarks A few things to get used to, the screen buttons need to be pushed harder then any other phone I've had. IMPORTANT...the "recent apps" which is usually on the home button long hold is on the menu button on the zmax. It might be my imagination but I think the 4g antennae handles more bandwidth as I seem to get 5 mgs more with the zmax then I did with the mega. This phone has sharper edges then the mega, feels much smaller in the hand and is easier to hold for me, I have medium sized hands and holding either phone is not an issue for me Battery life on all big phones is usually great as the battery is commensurately larger then smaller phones Another thing It was disappointing I did not have the option to move apps to the sd card and wanted root just for that, but just found out by installing the app called "move app to sd card", on this phone it seems the sd card is shared by the os with the hardrive so there is no need to move apps to the card!, to me that is a great solution and one I would prefer if given a choice Am looking forward to root but I really do not know what I am going to do with it since the phone has a stripped down os already


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text: This company was GREAT! They were professional, fast and polite. I called on a Saturday afternoon and they had the junk picked up (2 small BBQ's, metal frame hammok, metal garage door motor thing, and a metal stool) before 1pm the following day. For only $45!! They quoted me pick up between 12-4pm and were kind enough to call when they were running behind (even though they weren't)-it was picked up by 1pm. You do not have to be home either. I will absolutely use them again. Rachel D.


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VIDEO – Restore Our Future Ad: Rick Santorum says "I don't care what the unemployment rate is going to be".
It also accuses Santorum of being in favor of worker's rights – "he even voted against national Right to Work legislation". We know Mitt Romney is against worker's rights, but we did not know he was advertising that. We assume after the primary ol' Etch-A-Sketch will shake away everything he is saying now.


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Chelsea FC - Season Review 2003/04 Trailer (2004)
Official highlights of Chelsea's memorable 2003/2004 season. Claudio Ranieri and owner Roman Abramovich put together an excellent team with the purchase of up-and-coming star Scott Parker and a selection of fine domestic and international players. The team made superb progress in the UEFA Champions League, defeated Lazio 4-0 and at home reached the top three in the league with victories against Manchester United and Tottenham Hotspur. Every goal is shown here, as well as interviews with the players, all presented by Tim Lovejoy.
Watch the official Chelsea FC - Season Review 2003/04 2004 trailer in HD below or find more Chelsea FC - Season Review 2003/04 videos on Vidimovie.


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Admission to Abbotsford
Patients must be 18 years or over and require a GP referral for day programs. For inpatient admission, a referral must be made to one of our accredited psychiatrists.
Inclusion criteria
To be admitted to Abbotsford, patients must meet our inclusion criteria:
- 18 years or over.
- Ambulatory and self-caring with respect to showering, feeding and toileting.
- Physically well enough to not need general hospital care.
- Mentally and cognitively well enough to manage in an open voluntary hospital where patients are free to exercise, socialise and dine out of the hospital, if they wish, after their daily therapy concludes.
- Suffering a mental, psychological or social issue requiring hospitalisation.
- Under the care of an accredited medical practitioner.
- Preferably, a member of a private health insurance fund.
Health Cover
Abbotsford is a preferred provider with most private health insurers, for inpatient and day patient care. Coverage is dependent on a patient's level of cover with their fund. We recommend contacting us and your health fund in advance to discuss the proposed treatment and any related expenses.
Admission Enquiries
Our patient coordinators can answer any questions you may have, as well as discuss the referral process and treatment to suit you. We also offer support programs for carers and family members of people experiencing mental health issues.


text:
(CW) – Supernatural is new Thursdays at 8/7c on The CW Springfield.
Mary (guest star Samantha Smith) asks Sam (Jared Padalecki), Dean (Jensen Ackles) and Castiel (Misha Collins) for help on a case she's working but neglects to mention the British Men of Letters are involved. When Mary is double crossed, everything is revealed.
Richard Speight Jr directed the episode written by Davy Perez (#1212). The episode airs on February 16, 2017.
Click here to view the video on you mobile device >>
Connect with Supernatural Online:
Visit Supernatural WEBSITE: http://on.cwtv.com/Supernatural
Like Supernatural on FACEBOOK: https://www.facebook.com/supernatural
Follow Supernatural on TWITTER: https://twitter.com/cw_spn
Follow Supernatural on INSTAGRAM: https://instagram.com/cw_supernatural
Join The CW Springfield on Social Media for more news, trailers, and behind the scene interviews of your favorite CW shows:
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Follow The CW Springfield on TWITTER: http://twitter.com/CWSpringfield
Sign Up for Text Alerts: http://wwlp.com/2015/02/28/the-cw-text-alerts/


text: You must be over 18 to buy whisky from the Whisky Tasting Club. At present we can only post tastings to the UK. Contact us or read our frequently asked questions for further information. The WTC supports responsible drinking, visit www.drinkaware.co.uk if you need advice on what this means. Follow us on Facebook


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KNOW the Organisation: The first and biggest priority at this point of time is to understand the people of different departments and the structure to ensure seamless working. I am understanding the strengths of the organisation, where we need to strengthen as an organisation, and, overall, grasping its culture.
FOCUS: As an organisation, we plan to focus three-four projects every quarter in hand and work diligently on it. For example, Myntra worked on the launch of 'All About You' this quarter, on making sure that some app features are launched and ensuring their effectiveness for Myntra.
Also read: All About You to be a $100 mn brand in 2 years: Myntra
ENSURING product features: As we have moved to app-only, I think product features are the real reasons for being sticky. I want to make sure that we introduce Myntra Version 2 that we are planning in early November. It would have a bunch of features for creating social network, sharing and style forums where people can ask questions and get answers. A bunch of features are going to be introduced very soon which will be very helpful to consumers.
THINKING through by January for the next two years: I want to give myself three months to come up jointly (with the management) with the conclusion what would the big bets that we are going to make.
During the recent five-day 'Big Billion Day' sale, Narayanan said, the Myntra app recorded a six-time jump in traffic and 3.6-fold increase in revenue compared to the average day. But, he didn't disclose the actual numbers.


text:
3DOcean Zombie Guy 10223 tris 8568116
3DOcean Zombie Guy 10223 tris 8568116
3D Model \ Humans \ Male \ Teens and Adults
Ugly \ Skin \ Realtime \ Undead \ Walking \ Zombified \ Zombie \ Dead \ Monster
3D Model - Zombie Guy 10223 tris 8568116 by codethislab3D @ 3DOcean
3D Model \ Humans \ Male \ Teens and Adults
3D File Formats Included: .fbx (multi format); Animated: Yes; Created In: 3ds max 2011; Geometry: Polygons; Low-poly: Yes; Materials: Yes; Poly Count: 10223; Rigged: Yes; Textured: Yes; UV Layout: Yes.
This model was realized using 3D Studio Max (version 2011) and scanline rendering engine, so it is optimized for working in this environment.
We can not be held responsible for the use of this model in environments different from the recommended one.
The model is a low poly composed by quads and triangles distributed across the topology in a well balanced way.
The rendering shown was made using default scanline materials and scene setup provided in the file MAX.
The renderer visible in the scene can be obtained just using the native file.
Textures are 2048×2048.
All textures are in TGA format.
The models are rigged using the standard 3ds max biped.
The package includes 8 animations.
-Idle (from frame 0 to 88)
-Hit front (from frame 89 to 118)
-Hit back (from frame119 to 165)
-Bite (from frame 166 to 242)
-Walk (from frame 254 to 311)
-Left strafe (from frame 325 to 382)
-Right strafe (from frame 383 to 442)
-Death (from frame 451 to 509)
The FBX format included in the package can be used as it is provided, and is not editable. To get a similar quality of rendering images of the gallery, you must set the materials, lights and photo set independently.
For any questions or doubt please feel free to contact us.
Please don't forget to vote the model. We would really appreciate this. Thank you!
White Soccer Goalkeeper 9609 tris; White Soccer Player 9615tris ; White Boxer 7548 tris.
Keywords: animated, blood, character, creature, enemy, evil, fps, game, horror, lowpoly, monster, realtime, skin, ugly, undead, walking dead, zombie, zombified.


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Fifth fine of the year for Southern Water
Southern Water has been fined £9,000 after a failure at its Polegate Pumping Station near Eastbourne caused sewage to pour into a river for three days. The conviction was Southern Water's fifth in 2004 and twelfth in as many months.
Sorry you do not have access to this article. Please contact Customer Support at
or call 020 8267 8120


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Which one? They are so cute!
- Dalmatian Puppies!Vote A
- Pug Puppies!Vote B
- Golden Retriever Puppies!Vote C
Most Helpful Guy
Golden retriever, because it looks the most like my dog. Also, I'd like to thank you for making these pictures be the last thing I see before I log off and go to bed.11|00|0
Most Helpful Girl
I'd go with a Dalmatian. They aren't commonly seen where I'm from and I'd just love to have me a spotted little ball of energy as company.11|00|0


text: On Sunday 01 August 2010 10:32:15 Max Brazhnikov wrote: > SVN commit 6451 by makc: > > Revert tijl@ kdirwatch patch, it brings more problems than solves. I'll have another look at it, but it's definitely best to keep it out of 4.5 for now. Just to be sure, are there other problems besides plasma-desktop using 100% cpu? -------------- next part -------------- A non-text attachment was scrubbed... Name: not available Type: application/pgp-signature Size: 228 bytes Desc: This is a digitally signed message part. Url : http://mail.kde.org/pipermail/kde-freebsd/attachments/20100801/3bc26c82/attachment.sig


text: 12 Restaurants That Matter Monday April 6, 2009 Posted by admin From the April 2009 edition of Saveur magazine: Of course, they all matter - all the good ones, anyway. But why do the dozen restaurants featured here mean more to us than others? For one thing, they have profoundly influenced the way we think about food. Just as important, though, they delight us, dazzle us, and comfort us in ways that make us feel both at home and utterly transported. Some of our favorites - listed in no particular order - are enduring landmarks, like Commander's Palace in New Orleans, that reconnect us with the spirit of an earlier golden age of dining. Others are pioneers, like Blue Hill at Stone Barns in upstate New York, that take us closer to our food's roots and show us just how much more delicious locally grown ingredients can taste. Still others accomplish a thoughtful translation of an indigenous cuisine, as does Charles Phan's Vietnamese-inspired fare at the Slanted Door in San Francisco. And then there are the restaurants, like the French master chef Joël Robuchon's Las Vegas temple of haute dining, that transcend place altogether, immersing us in a total sensory fantasy. 1. Joel Robuchon 2. Sportello 3. Commander's Palace 4. Topolobampo 5. Canlis 6. Gramercy Tavern 7. Manresa 8. Watershed 9. Marlow & Sons 10. Musso and Frank 11. Blue Hill at Stone Barns 12. Slanted Door


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Following in the footsteps of recent long-form journalism start-ups, the PostDesk online platform launched today intent on reinvigorating discussion about long-form content among internet users, according to BetaKit.
PostDesk will cover in-depth news and analysis in the fields of tech, gaming, culture, politics and business, the article said. Only those with early invites can currently access the website, though the temporary PostDesk blog is available to all users.
"PostDesk is a place to discuss, debate and read free, independent long form content such as in-depth news, reviews, investigative journalism, analysis, critique and controversial opinion pieces," according to PostDesk's CrunchBase profile.
A combination of in-house editors and outside contributors will be responsible for PostDesk's content, BetaKit said. Readers will also have active roles in PostDesk, earning points and badges for thought-provoking comments and perhaps even being asked to contribute articles, BetaKit said.


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I went into slight panic mode this afternoon. Life 14 needs to be started and I began by drawing an image onto white cloth. The photo shows the process although it looks a bit gawky at this stage. I have a rubber in my left hand and a pencil in my right and I'm not sure which hand I use most!
Often when I draw my mind wanders off, and I began to think about the exhibitions that are coming up next year, and realized that I hadn't got enough quilts made to cover the 3 events that I'm committed to. Heck! There's such a short time to go, so I allowed myself a quick panic. I just can't work at the last minute against a deadline, I have to be organized and ahead of myself.
So I went through my list of titles and plans to see which ones would be best for which shows. I've made a slight change to those plans, but am not entirely convinced yet. It means I have to stop working on the above quilt which was going to be called "What Do You Mean, What's For Dinner?".
But, tomorrow is a new day, and I'll begin again. I shall make Life 14, 15, and 16 in the next few months. Keep tuned if you'd like to see how "Making Time", "Poisonous Plant", and "The Life of Time Is Motion" develop.
Thanks for listening.


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This farm, near Viroqua, Wisconsin was homesteaded by my friend's family in the 1800's. Over the last century-plus this fertile soil has seen various states of production and decline...
Saved from the speculators by the current steward, this homestead is back in production... producing arguably the world's best organic ice cream.
work on our Documentary Film
::: :::
Read more of my Journey - visit my Blog
This Page, Text and All Images, Copywrite © 2007 Macastat, All Rights Reserved


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We offer a range of projects from undergraduate to postgraduate level, covering problems in software development, data mining, visualisation, modelling and simulation. Projects can be conducted 'in-house' or with national and international partners. We are also able to support successful students with industrial placements in Germany, Europe and overseas. See the Project Page for further information. Contact Prof. Olaf Wolkenhauer any time for further information.
All topics listed can be worked on as a student assistant or in final year projects as part of a degree.
Develop your own topic with the help of our group members based on our current research topics, too.
We are constantly seeking interested students who want to get involved in cutting edge research as part of our research group.
Available topics:
Find open posts under Jobs.


text:
Graham Swift Long Fiction Analysis
(Survey of Novels and Novellas)
Graham Swift is one of a number of British writers who emerged in the early 1980's to revitalize the English novel by experimenting with new thematic concerns without sacrificing the genre's roots in realism. Among these are Peter Ackroyd, Julian Barnes, A. S. Byatt, and Penelope Lively. Swift's work shares with theirs a concern for the relationship between fiction and history, between memory and the reconstruction of the past. His novels almost exclusively employ one or more first-person perspectives, and the reader is left to contemplate the "gap" between what one might consider objective reality and how that reality is constructed or refracted by the respective narrators. These narrators are not so much unreliable as they are both the creators and the products of their own pasts. Swift's novels as a whole are marked by the absence of communication, and it is never clear to the reader to whom the narrators' words are directed. In this sense, they often read as internal and reluctant confessions, marked in many instances by the desire for personal exculpation.
The Sweet Shop Owner
Swift's early work draws on a number of modernist techniques, such as stream of consciousness, shifting perspectives, and a concern for the experience and passing of time. This is particularly true of Swift's first novel, The Sweet Shop Owner, which offers a single June day in the life of Willy Chapman. The allusion to Virginia Woolf's Mrs. Dalloway (1925), and more distantly to James Joyce's Ulysses (1922), is no accident. The Sweet Shop Owner opens with Chapman contemplating a letter from his daughter severing ties between them. Subsequently, it develops in two directions: following Willy through this, the last day of his life, and tracing the events of the previous forty years leading up to this point. As in subsequent novels, Swift is concerned here with the breakup of family structure and the barrenness of modern life, isolation punctuated occasionally by poignant connections and missed connections.
These themes are taken up in Shuttlecock, in a rather more pointed way, particularly in terms of epistemology (the way in which we understand or make sense of the world). The narrator, Prentis, works in an obscure government archive office under the watchful eye of his boss, who often requests files and reports that are missing or incomplete. The paranoia this creates in the narrator reaches a climax when these requests seem to bear on the past of Prentis's own father, known to all as a war hero. Ultimately Prentis is, like the reader, faced with two profound and contemporary questions in terms of the problems of knowledge and textuality: Is his father's heroic memoir fictional or true? Given the opportunity to discover the truth, should he do so or not?
The Light of Day and Tomorrow
The questions raised in Swift's second novel are reminiscent of those posed by detective fiction, which is preeminently concerned, of course, with epistemological certainty, with solving mysteries, with determining the truth. Similar elements are found in Swift's later novel The Light of Day, in which the narrator is a detective. In typically Swiftian fashion, however, the structural components of the detective-story genre are thoroughly subverted, to the extent that solving the apparent crime is one of the least significant of the novel's concerns; rather, the narrator of The Light of Day fuses past and present to create an extended meditation on the nature of love and human relationships. Tomorrow also generates suspense toward some unstated (until the end) climactic event; the narrator reflects late one night on a family secret that will, when revealed to the children in the morning, profoundly affect their lives and the family as a whole. Notably, Swift employs a female narrator-interior monologuist for the first time in Tomorrow and, again, his ability to create a genuine and credible narrative voice is evident.
Out of This World and Ever After
If in Shuttlecock the narrator is confronted with a profound dilemma—to know or not to know the truth—Swift's ensuing novels explore the characteristic postmodernist epistemological concern of whether such knowledge is even...
(The entire section is 1791 words.)