text:
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TeddyK necesitaba un nuevo diseño de logotipo y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 131 diseños de 25 diseñadores freelance.
Black Diamond
We do everything from mount TV's, install HomeTheater equip to integrate your entire home(audio/video/security/lightiing/internet/heating-ac/web so that you can control it from your phone anywhere in the world. We build custom built-ins that will raise a TV out of it and then hide when not in use. Ideally this logo would be fit perfectly on a TV screen. (9:16) as it will be on a TV on a graphics package going on our fleet.
This tricky because we"ve realized the way into people homes is mounting TV's. Once we are in we can introduce other service's and options.
However that being said ideally we are pushing toward the higher end market. Upper middle class, men, gadgety, upscale, sports, etc. We are targetting high profile, ballplayer, ceo,cio coo type.
I want a sharp effective logo that drives interest and leaves an impression of hightech, streamlined, service vaue oriented. Colors we use now are black white royal blue silver/grey. I don't know what I want so I will leave it up to the community here. itr could involve tv's, remote controls, speakers or just the right sleek design with the right font....I'll know when I see it and will work with who ever works with me to refine. We are creating a brand of Black Diamond Home Technolgy to market specificly to installing TV's so this Logo should aim toward the home integration. That name which is being trademarked will is going to be a blast to design and will give this projects winner a first shot!
Thanks Everyone!!!
Descubre cómo funciona un concurso de diseño u obtén más información sobre nuestros servicios de diseño de logo.

subset: commoncrawl


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The Oakland Raiders will trade a late-round pick for Houston Texans quarterback Matt Schaub, according to ESPN's Adam Schefter.
Schaub signed a five-year, $66.15 million contract with Houston in 2012, but failed to live up to that deal. He bottomed out last year, losing his job to Case Keenum as the team finished with a league-worst 2-14 record.
The Raiders have an awful recent history of acquiring quarterbacks. They spent $21.5 million and four draft picks acquiring QBs between November 2011 and November 2013.
The carnage:
- Traded for Carson Palmer in 2011. Gave up a 2012 1st-round pick and a 2013 2nd-round pick. Paid him $15 million before trading him to Arizona.
- Traded for Matt Flynn in 2013. Gave up a 2014 fifth-round pick and a late-round 2015 pick. Paid him $6.5 million before cutting him last November.
They've also dabbled with Terrelle Pryor, Matt McGloin, Matt Leinart, Jason Campbell, and Kyle Boller in the last three seasons. None of them stuck.
The Raiders have a ton of cap space, so Schaub's $14.5 million cap figure is a non-issue.
The big question is whether or not this will affect their willingness to take a quarterback in the NFL Draft. The Raiders have the fifth pick, which puts them in position to draft guys like Johnny Manziel, Blake Bortles, or Teddy Bridgewater.
They could see Schaub as a transitional QB who they can use in 2014 and discard when the QB they draft comes of age. Or, more likely, they see him as a quick-fix who will make them a contender immediately — which has been their downfall in the past.


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Apple TV hackers called to create open source set-top
You have nothing to lose but your CableCards
Neuros Technology has called on Apple TV hackers to join it and develop a next-generation open source set-top box to prevent IPTV falling into the hands of the Man.
Neuros launched its Linux-based OSD last autumn. It's a media centre that can digitise video content to connected storage - either a locally fitted USB drive or memory card; via the unit's LAN port to a networked computer or NAS box; or to an iPod, PSP or other portable media player.
Like other Neuros hardware, the OSD is largley based on open source software - though some elements, thanks to the need to use third-party components, remain closed - and the company encourages its customers to hack the code and share their work with other owners. The upshot, it reckons, is improved functionality and support for more digital content formats.
Which is, of course, one reason why so many folk are hacking Apple's Apple TV, for example adding new codecs to allow the $299 'Mac Nano' to play DivX files.
This, says Neuros CEO Joe Born in an open letter to Apple TV coders, is to be encouraged if the vested interests - content providers and the hardware manufacturers who have stakes in them - seek to lock down what consumers can watch, where and when.
To prevent that happening, he believes, the world needs not only open hardware - Neuros, after all, is already producing that - but also and crucially major momentum behind the software development work that allows the hardware to support more devices and more formats, thus making it relevant to more consumers.
Of course, Neuros benefits from all this financially, by selling more hardware, an activity threatened by Apple TV, particularly given its hackability, but Born clearly hopes to free the company from the proprietary technologies even the OSD has to contain, in part by using clever code to do the same job on more open components.
It's not for the mainstream, perhaps, but there's something to be said for truly opening access to IPTV and preventing the greedheads dominating a new televisual medium and eroding the audience's viewing rights. And that has to be a better goal than simply making one platform slightly less proprietary than it currently is.


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Bouncer At Dos Gringos Knockouts Some Dude! [In AZ]
Video of a Scottsdale club bouncer punching a patron! This video is making rounds all over news stations&IP=22.214.171.124
Please click the "Report" button below if the video on this page is not working properly.
Comments will only be displayed by verified emails. No Spamming or Racism.


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adryenn needed a new print or packaging design and created a contest on 99designs.
A winner was selected from 50 designs submitted by 23 freelance designers.
I need tshirts, logo and book cover design (front and back). Bold and empowering, not woo woo, but not too corporate either. Strong and upbeat.
Be A Yes!
The concept is to empower the reader to "Leap and the Net Will Appear", "Say Yes, Then Figure Out How", and "See The Opportunities All Around You"
It's aimed at entrepreneurs and small business owners.
- Bold
- Easy to read
- text styling only
- Feminine
- Mind Body Spirit


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ANAHEIM – Authorities have identified a man struck and killed by a Metrolink train while walking along the tracks in Anaheim.
Orange County coroner's cffice officials Tuesday afternoon identified Sergio Narez, 51, as the man struck by a southbound train while walking alongside the tracks south of La Palma Avenue and east of Pauline Street shortly after 4:30 p.m. Monday.
Police are treating Narez's death as an accident, saying they have seen no indication that he purposely stepped into the path of the train.
Authorities believe Narez was walking southbound when the train struck him. It wasn't clear why he did not hear the train approaching from behind him.
Coroner's officials said Narez had no known city of residence.
Narez's death marked the second time in recent days that someone has been struck and killed by a Metrolink train in Orange County.
Andrew Powell, 20, of Fullerton was struck and killed on the tracks near Brookhurst Road and Commonwealth Avenue shortly before 3:30 p.m. Friday.
Both train incidents caused lengthy delays for commuters.
Contact the writer: 714-796-7939 or email@example.com


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Free Standard Shipping offer is valid on orders $50 or more placed online at organictraditions.com for U.S. or Canada Standard Shipping. No promo code required to redeem free shipping, just select Standard Shipping during checkout. If any other shipping options is selected, the stated shipping and handling fees will apply. If you return a portion of your online purchase, shipping charges will be assessed for the return shipping costs. Sales tax is not included in total minimum purchase requirement calculation. Not valid on previous purchases. Offer is subject to change without notice.
Organic Probiotic Sorghum Cereal Chocolate Coconut Crunch
Organic Traditions® Probiotic Cereal is a combination of organic sorghum flakes, chia, cacao nibs, cacao powder, shredded coconut, hemp seeds, cinnamon and beneficial pre and probiotics. This powerful blend of nutritious seeds and other nutrient dense superfoods will change the way you fuel yourself at breakfast. Packed with incredible seeds suchas chia, flax and hemp, providing you with a source of fiber and a ton of vitamins, minerals and antioxidants. These mild, nutty seeds are a fast and simple way to enhance your daily diet with an extra boost of fiber and dense nutrition.
A Synbiotic Superfood Formula Improving Your Inner Flora With Bacillus Coagulans & Prebiotics Beyond extraordinary nutrition, Organic Traditions® Probiotic Sorghum Cereals deliver healthy live probiotics, which are fundamental for supporting optimal digestive and immune health.* Enhanced with the premium probiotic strain Bacillus coagulans GBI-30 6086, which has excellent survivability and stability, safety and efficacy, you will promote optimal gastro-intestinal health with every bite.* A breakthrough in probiotic supplementation, this shelf stable, food-friendly beneficial bacteria survives stomach acidity and does not require refrigeration and can be added to both hot and cold drinks and recipes.The addition of acacia gum prebiotic fiber makes this an all in one pre and probiotic blend thereby making this a synbiotic superfood formula. Prebiotic fibers are sources of food for beneficial probiotics and therefore support gut health by maintaining the optimal growth and balance of beneficial bacteria.*
Cold Milled Milling Omega-3 rich seeds such as chia and flax seeds is extremely difficult. Our proprietary milling process finely slices the chia and flax seeds without crushing them or forcing them through a mesh or sieve. This minimizes oxidation and the consequent degradation of delicate nutrients. The end result is a perfectly milled, uniform powder that is shelf stable with a broad range of applications.
- Powerful blend of nutritious seeds and superfoods
- 1 billion probiotics per serving
- Excellent source of Omega 3 fatty acids
- High in iron
- Delicious chocolate coconut taste
|Item Size
|7 oz (200g)
|Overview of Key Benefits
Antioxidative Support Chia contains high amounts of antioxidants that act as a naturally occurring stability system for the delicate Omega 3s. Quercetin for example prevents lipid oxidation therefore making this seed a stable source of Omega 3. The antioxidant profile of flax seeds points to the free radical scavenging potential in response to oxidative stress.
|Recommended Uses
- Enjoy with your favourite milk or milk substitute
- Use it as a topping for your yogurt and oatmeal
- Use as you would any of your other favorite cereals
|Key Features and Benefits
Certified Organic
Allergen Information: Produced in a facility that packages tree nuts (Almonds, Hazelnuts and Cashews). The facility is dairy-free, gluten-free, soy-free and peanut free. The Erythritol and Organic Flavor are derived from Organic, Non-GMO corn. Storage Information: Store in a cool, dry, dark place. For optimal freshness, product may be refrigerated after opening.
- Powerful blend of nutritious seeds and superfoods
|Supplement Facts


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CORE has members in four continents (see the CORE member listings). In order to register domains, CORE members compete in an open environment. There are no territorial assignments and the customers can freely choose the CORE member they want to do business with. Moreover, after registering a name, registrant can change the CORE member.
The CORE Secretariat is based in Geneva, Switzerland. The secretariat is in charge of activities that have to be handled centrally. The secretariat must treat all members equally and does redirect a customer to any specific CORE member. Inquiries and requests for registrations should not be directed to the Secretariat but directly to a CORE member.
The new domains
CORE has been launched in order to create the following seven new generic top-level domains:
- .firm For businesses or firms
- .shop For businesses offering goods/services to purchase
- .web For entities or groups providing activities or services related to the World Wide Web
- .arts For entities/groups in culture and entertainment
- .rec For groups/organizations in recreation
- .info Information services
- .nom For people wanting to register their own name
The memorandum of understanding
CORE was created in October 1997 as a result of a rigorous process of global consensus launched by the Internet Society and the Internet Assigned Numbers Authority in fall 1996. The process started with the creation of the International Ad Hoc Committee (IAHC) to develop concepts for the registration of Internet domain names in a new era of deregulation and self-governance.
The Policy Oversight Committee succeeded IAHC. It developed specific plans for a global infrastructure for adding and administering new names, with CORE as the non-profit administrator of the gTLDs - the suffixes that serve as addresses to route mail and data on the Internet and help create an identity for each user wherever they may be. The concepts were formalized into the gTLD Memorandum or Understanding(gTLD-MoU), a working dynamic document and global constitution that clearly defines issues of authority, protocol, competition and growth in the domainname system.
There are already more than 200 signatories to the gTLD Memorandum of Understanding, including companies and organizations from around the world, such as: MCI Communications, Bell Canada, Digital Equipment Corp. (DEC), Internet Society(ISOC), Internet Assigned Numbers Authority (IANA), Internet Policy Oversight Committee (POC), Internet Software Consortium, European Telecommunications Standard Institute, France Telecom, Internet Society of Australia, International Trademark Association, Swiss Federal Institute of Intellectual Property, Tokyo Internet Corp. and the Internet Societies of Geneva, Vienna, Israel, Japan, Ghana, Norway, Mexico and Thailand.


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Devin Mesoraco makes his MLB debut
CINCINNATI — Devin Mesoraco's journey to the Major Leagues started June 1, 2007, when he was drafted in the first round with the 15th pick of the Major League Draft by the Cincinnati Reds.
That journey ended Thursday, when Mesoraco was called up from the AAA Louisville Bats and placed on the Reds' 40-man roster.
Now, a new journey has begun.
Since he was a young man, right here in Punxsutawney, Mesoraco has been a standout athlete, but at every new level comes a new question: Can he stand out at this level with the elevated competition?
Fans of a Cincinnati team that won the National League Central last year, but finds itself (NUMBER) games behind the St. Louis Cardinals and out of the playoff race already this season, hope the answer the latest question will be yes.
Even with two standout catchers already at the Major League level in Ramon Hernandez, who is hitting .287 with 11 home runs this season, and Ryan Hanigan, who is hitting a respectable .270 as the backup catcher this season, Cincinnati has still been abuzz all season about the young catcher putting up big numbers in Louisville.
In 120 appearances at Louisville this season before his call-up late Wednesday, Mesoraco hit .289 with 36 doubles and 15 home runs and an OPS of .855.
And, the fact that his defensive game comes just as well-touted as his numbers at the plate do gives those Reds' fans good reason to be excited about his future.
Mesoraco was thrilled to get the big call, though he admitted there was no actual call involved.
"When I got to the field, they kind of let me know, then," he said. "The manager kind of pulled everybody aside and told us individually."
Mesoraco said that although he had to wait until Wednesday afternoon to get the official word, he had been given a hunch that he might get the call, so he was prepared.
"I had a pretty good idea," he said. "My manager had pulled me aside earlier in the week and given me a pretty good indication, so I had all my stuff packed and ready to go."
After the Bats' contest against the Columbus Clippers in Louisville Wednesday, Mesoraco and his teammates who also got the call were Cincinnati-bound.
Mesoraco spent Wednesday's contest on the bench watching, giving backup catcher James Skelton an opportunity to start.
"I think this is kind of where I imagined I'd be when I was drafted," Mesoraco said in a phone call on the way to Cincinnati. "It was a long road, but now, I can say that it's all been worth it."
Reds' manager Dusty Baker said Thursday Mesoraco isn't expected to play immediately, distilling the rumors that he might appear in his first game as Reds' catcher.
"The first couple of days, he will catch some bullpens, because there are some guys he hasn't caught," Baker said. "And there are some he has caught, but not for a long time. So, he'll be in the bullpen learning ... Right now, we're going to let him get acclimated to the way we do things. You have to learn the personnel and go over the scouting reports."
Mesoraco, who has been quietly and humbly awaiting his turn in the Majors, remained humble about the opportunity to learn at the Major League level.
"I don't see it as a pressure situation," he said. "I'm coming up to learn, and learn from two good catchers in Ramon and Hanigan. I'm just going to go up and do everything I can to better my game and hopefully improve on it for the future."
Mesoraco may not have been in Thursday's lineup, but he did take the field in a different context, warming up the pitcher between innings on one occasion while Hanigan dressed.
Mesoraco summed up his experience Thursday quite simply after the game, saying, "It was just a thrill to be part of my first Major League game. Hopefully, one of many."
Punxsutawney hopes so, too, Devin.


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We are pleased to invite you to learn more about our unique immersion program and school community.
Our after school language classes provide a fun and effective way for preschool and elementary children to learn Mandarin or Spanish language skills.
To register online click your campus below:
Home > Mandarin and Spanish After School Language Classes – Upper West Side > HWIS 2018-19 After-school calendar – NY
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Trilitech needed a new logo design and created a contest on 99designs.
A winner was selected from 64 designs submitted by 24 freelance designers.
I'm looking for a logo for the site BankInstant.com. The purpose of this site is to compare rates on cds, savings accounts, mortgages, student loans, auto loans and other banking products.
A professional looking logo for BankInstant.com. I would like the raw vector graphic as a deliverable as well as a high-res raster export.
- A clean professional look
- Anything with a cartoon or casual feel
Find out how a design contest works or learn more about our logo design services.


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Israel News - Stay Informed, Pray Informed
US Republican presidential candidate Mitt Romney on Saturday committed himself to staunchly supporting Israel in its showdown with Iran should he win November's election against President Barack Obama.
"I would make it very clear that for us, as well as for them, it is unacceptable for Iran to become a nuclear nation," Romney told a Christian political gathering in Pennsylvania, where he accused Obama of being "more frightened that Israel might take military action than he is concerned that Iran might become nuclear."
The unequivocal declarations of support for Israel were seen as an effort to boost Romney's elect-ability among conservative Christians, a segment of Republican voters with which Romney is unpopular with due to his Mormon faith.
In related news, the results of a survey published this week showed that a 70 percent majority of Israelis view America as a strong and reliable ally, and 91 percent fully believe that if Israel were facing an immediate existential threat, the US would come to her aid.
On the other hand, a growing number of Israelis do not trust Obama. Only 38 percent of Israelis said they have a positive view of Obama, while 23 percent do not like the US president at all. The rest responded with a neutral stance.
Should Romney succeed in his White House bid, 30 percent of Israelis believe the Republican will improve US-Israel relations, while 26 percent see relations remaining the same as they are today. Only 6 percent felt Romney would be worse for Israel than Obama.
The survey was carried out by the Begin-Sadat Center for Strategic Studies, the Bar-Ilan University Center for International Communication, and the Anti-Defamation League.
Want more news from Israel?
Click Here to sign up for our FREE daily email updates
For Information & Reservations:
E-Mail: email@example.com
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Free to Your Inbox


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Mary Jane Akers, 89, Kokomo, passed away on April 2, at her home. She was born Sept. 2, 1923, in Peru, to Edgar D. and Agnes (Hummer) Ernest.
On Sept. 30, 1978, she married Jerry Akers, and he survives.
She worked at Haynes International and retired in 1983 after 33 years of service. She enjoyed playing bingo and playing with her dogs.
In addition to her husband, she is survived by her sister, Patricia Miller; half-sister, Jo (Albert) Chakmak; half-brothers, Chuck (Carol) Ernest and James (Theresa) Ernest; brother-in-law, Guy (Charlene) Akers; and nieces, Diane Brown and Denise Farringer.
She was preceded in death by her parents; half-sister, Wanda; and her first husband, William Erbaugh.
The funeral service will be held Friday, April 5 at 2 p.m. at Sunset Memory Garden Funeral Home with Pastor Mike Ennis officiating. Visitation will be from 12 to 2 p.m. at the funeral home. Entombment will follow in Sunset Memory Garden Cemetery.
Messages of condolence may be expressed online at www.sunsetmemorygarden.com.


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law enforcement
80% of all assaults on law enforcement officers are carried out with fists and hands.
correctional officers
Correctional officers face 33,000 assaults by inmates every year. That's 90 assaults everyday.
private security
One million private security personnel in the U.S. facing similiar threats as law enforcement officers.
civilian protection
Offenders used a weapon in only 1% of all sexual assaults. Most often fists and hands are used.
No-Contact LLC
, is a research and development company focused on wearable technologies synthesizing advanced textiles with electronics and computation for personal protection and safety.
Our mission is to help protect security personnel, law enforcement officers, military and civilians using the latest in wearable technologies.
Conducted Energy Clothing
is a proprietary technology developed by No-Contact LLC to assist security personnel and law enforcement officers confronted with close-quarter assault situations involving attacks with fists and hands. Conducted Energy Clothing (CEC) act as a last line of defense during an assault. When activated, an aggressor touching the exterior surface of the CEC receives a high-intensity non-lethal charge that causes them to immediately withdraw contact.
No-Contact LLC is working with the U.S. Army Science and Technology community, Special Ops forces developing prototypes.
No-Contact.Com © 2010 |
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Tags: slutty, tory, lane, strips, down, pink
Pornstars: Tory Lane
Submitted: 9 years old
Copyright © 2005 - 2019 DaChix.com - All Rights Reserved.
Support / Contact
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All actors and models appearing on this website are 18 years or older. Section 2257 DMCA
"Slutty Tory Lane strips down in pink" - Watch "Slutty Tory Lane strips down in pink" by Tory Lane for free on DaChix.com


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Care in South Africa by Connor Quinn
I spent the best month of my life in Cape Town. Going in, I was not sure what to expect, from my doctors and family warning me about the disease and crime, I was quite wary. I arrived on a Friday morning when all of my soon to be housemates were out at their projects, so it was just my host family and me. It was a bit awkward at first but once we got to know each other, I felt at home and quite relaxed.
That night I met all of my roommates. They were from Switzerland, France, England, Italy, Connecticut, Luxemburg, Japan, and Canada, all in the same house! They became some of the best friends that I have ever had.
For the first week, I only had one project, the Surf programme at Muizenberg Beach. I went in not expecting to get so attached to the kids that I worked with, but after the first day I really loved each and every one of them. I would have to catch the ten o'clock train to arrive at the beach by around 10:15. Once arrived, I would suit up and surf with co-volunteers till about 12 o'clock. We would break for lunch then return before the kids walked over from Capricorn Primary. The surf programme is not mandatory so kids had the option of showing up one day but not the next, which meant we were sometimes over or understaffed.
We would stretch and warm up for about 30 minutes to get everybody used to their suits, then grab boards and go into the water. We tried to have one volunteer per every two children. It was a blast! I got to know about 8 kids really well. To learn about their home situations and what they have experienced was life changing for me. After the kids were gone I would dry myself off, then change to catch the 6 o'clock train home. Once home, my host mom would have dinner waiting for us, always huge servings of amazing new foods.
For the next three weeks, I worked on two projects, Surf programme at Muizenberg Beach, and a Care Project at Little Eagles Educare in Vrygrond, Capricorn. I thought that I had been working with people that had it bad but my eyes were opened at Little Eagles, where we were in the heart of poverty. I was used to just working with the kids from an informal settlement, not actually going in and working in these communities for the day.
At first, I was greeted by over 60 kids and just 2 teachers and the principal. I taught 2-7 year olds how to write, count, colours, etc. For my first two days there I didn't really know about the kids that I worked with but when teacher Jolie sat me down and told me about their lives, I was in shock. From learning about the 2 year old's mom being only 11 to most of the kids being HIV positive. Those facts did not scare me away at all, I feel like I got closer to them if anything.
During the nights and weekends, it was our free time. My only suggestion is to take advantage of every minute and before going, have ideas on what you want to experience while you are there. Every night was something new and amazing. We would go to downtown Cape Town one night and the next day be on a safari.
I honestly can say that my month there was the best in my life. Looking back, even the moments on the train or in the taxi, which you think at the time are boring, were all fun and different. I loved talking to everyone, experiencing their culture and hanging out with them. Not only did I learn about them, I learned a lot about me. Everything was just amazing!
Once I arrived back home, I was a changed man. I am more accepting and can tolerate people easier now. Some of my best friends now are from all over the world and I still talk to them weekly. I hope to continue doing this type of volunteer work in the future.
Connor Quinn
+44 (0) 1273 007230


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- Brad Smith felt sparks with Whitney and he gave her the first impression rose. Who is Bachelor Canada's Whitney? Check out her bio below.
- Name: Whitney
- Age: 24
- Occupation: Administrative Assistant
- Hometown: Calgary, AB
- Do you have siblings? I have an identical twin sister named Camille. She is my best friend.
- Do you have a nickname? What is it, and how did you get it? "Diva." I don't leave the house without a pair of heels.
- What one thing about you would we never guess just by looking at you? I can throw a football farther than most men.
- Tattoo Count: One. It's on my lower back and says "live life to its fullest" in Chinese.
Bachelor Canada: Who is Whitney?
11 comments:
- Anonymous said...
Whitney is hot and Brad would be a fool to let this one go.
- October 26, 2012 at 11:53 AM
- Anonymous said...
Hmmm honestly, she seems really wooden and overly competitive. She is always talking about winning the competition. I don't think that that is the point of the show! I think he would be a fool to pick her in the end.
- November 2, 2012 at 2:21 AM
- Anonymous said...
Yeah and also she is only 24 but has more wrinkles than me and I'm 36! I think she has gone to tanning beds too much or something. She has fake boobs, she doesn't seem sincere, she just seems fake all around.
- November 2, 2012 at 2:24 AM
- Anonymous said...
She is a strong woman and I find that very attractive
- November 3, 2012 at 9:03 PM
- Anonymous said...
She is an even bigger b***h in real life... If I were Brad I'd run and hide.
- November 5, 2012 at 9:13 AM
- Anonymous said...
Whitney probably isn't as bad as the show makes her look. She does have the popping vein in her head that makes you think otherwise though. I'm from Calgary and she's not even an administrative assistant. She's a server at a restaurant *roll eyes
- November 15, 2012 at 7:37 PM
- Anonymous said...
I think Whitney is an amazing person, she is extremely strong, driven and isn't afraid to go after what she wants. She came there for love not to make friends and its understandable to have your guard up coming onto a show like this one. I admire Whitney a lot.
- November 17, 2012 at 12:00 PM
- Anonymous said...
Whitney is a bipolar, self absorbed BIT€H!!!!
And we don't need Calagrians to tell us this, she proves it with every episode.
- November 22, 2012 at 8:16 AM
- Anonymous said...
Whitney makes Calgarians look bad!! What a shallow, stupid bitch.
- November 22, 2012 at 10:44 AM
- Anonymous said...
I've never seen a worse boob job in my life. There's actually a right angle where her breasts meets the implant. Very odd. She should get that checked out...
- November 26, 2012 at 12:04 PM
- Kirsty MacDonald said...
Whitney is such a strong, determined girl. She needs to know more about how life (and love) is but keep up with her decision making, then sticking to her decision. I think she would be best as the Canadian bachlorette and she will walk away just as she looks, in total control and beautiful. Stay strong Whitney, you are beautiful!
- January 12, 2013 at 7:36 PM


text:
Not finding what you're looking for? A few suggestions:
• Fewer words might give better results. Look up cats instead of funny cats.
• No need to search with the words videos or for kids included.
• Use related words: If searching for iceberg isn't working, try ice or glacier.
• Is everything spelled correctly?
• Browsing topics might help, too!
Topic: islands
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tcp179 necesitaba un nuevo diseño de logotipo y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 120 diseños de 29 diseñadores freelance.
Lemieux Network Consulting is a new company which needs a logo for business cards, a website, and other company materials. The company specializes in connecting the branch offices of its customers, and installing remote access VPN technologies using Cisco networking equipment like routers and firewalls.
The logo is for a company based in Vermont. It is a high-tech company focusing on using Cisco equipment to increase efficiency of its client's systems and productivity of their employees. Its clients are mostly small businesses like local restaurants, hotels, professional services offices. The company also plans to offer other computing services in the future like setting up of point-of-sale systems and small business servers.
The company has 11 years of experience in the information technology field. It also provides biligual (english/french) service to businesses in Northern Vermont and Southern Quebec.
- Item 1...Simple, modern design
- Item 2...minimal colors
- Item 3...The tagline could read "Lemieux" on one line, and right below in much smaller letters, "Network Consulting" but I am open for suggestions deviating from this guideline
- Item 4...If you could represent "Network Consulting" with an image, which doesn't necessairly needs to accurately represent it, it could possibly be ommitted from the tagline.
- Item 5...Maybe the logo could contain 2 spruce trees side by side (a bit in the same shape/style as the new logo of Cisco's Golden Gate bridge) which would not be too obviously similar and not look like the company is a nursery or related to nature.
- Item 6...If "Lemieux" can be made its own logo, with nice lettering not reproduceable with standard fonts, with "Network Consulting" below it, it could work too.
- A somewhat abstract logo that doesn't mean anything is great too
- Item 7... Styles of logos of companies I like: Burton Snowboards, Cisco, CBC, Apple, HP, Lenovo, Emerson, and many other similar ones.
- Item 8...Format needed: ILL, PSD, JPG, GIF, PNG
- Item 1...I don't want a logo that has "real" pictures or representations that look too real of things
- Item 2...Not too complicated
- Item 3...No old-fashioned or archaic designs
- Item 4...No nature or mountain pictures, although it's ok to use elements of this provided it looks modern.
- No logos that would convey a perception that the company offers some other "non-computer-related" services.
Descubre cómo funciona un concurso de diseño u obtén más información sobre nuestros servicios de diseño de logo.


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My Favorite Flirts is a feature that lets you reach your favorite Flirts easily from My Account or on 1-800-TO-FLIRT.Manage My Favorites
(0 Reviews)
Hi, My name is Olivia, you can call me Livie.
I'm a 20 year old college student..
I don't have pictures yet but I'm planning on getting some done real soon!
Keep checking!
I'm experienced with all types of fantasies,but I am not real submissive,
and I don't get into pain, however, I don't have no problem giving you some!,
I can handle anything besides those, give me a call I would love to play with


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Why It Works
In theory, combining all of the primary colors--red, yellow, and blue--in a single outfit sounds like a how-to guide for circus dressing. But there's nothing clownish about the visually rich ensemble Amanda Seyfried recently put together, and it's worth noting how she did it. While visiting Today in New York, the actress showcased a ladylike take on colorblocking with the help of Prada's sky blue Cashgora Leggero Single Breasted Coat ($3395) and marigold Cady Silk Ruffled Hem Dress ($1650, available select Prada boutiques), a red Celine bag, and nude Christian Louboutin heels. Though these three hues aren't typically considered complementary, the varied tones--paler shades contrasted with bolder pigments--create a directional and harmonious result. Keep reading for more details on Why It Works!
Coat: Stick to softer shades of blue when it comes to your outerwear, so as not to distract from the other colors. Since this piece is such a prominent part of your outfit, simple lines are key to keeping the entire look streamlined.
Similar Essentials: Max Mara Frida Coat ($533); Ted Baker London Double Breasted Cape Coat ($420); Pendleton Thames Walking Coat ($160) in Cambridge Blue Melton.
Dress: Look for a dress in paler shades of yellow--this is not the time for ultra brights--to complement your coat's lighter blue hue. Try a fuller skirt to achieve that modest, ladylike result.
Similar Essentials: St. John Collection Sleeveless Milano Knit Dress ($795); Sonia by Sonia Rykiel Shift Dress ($447); Ralph Lauren Blue Label Jocelyn Jersey Dress ($129) in Sunfish Yellow
Bag: Go bold with your bag. Bright red really pops against more muted shades. Tie the look together with a statement lip in the same cherry hue.
Similar Essentials: Diane von Furstenberg 440 Top Handle Small Satchel ($545); Tory Burch Robinson Small Dome Satchel ($495); Coach Legacy Leather Mini Tanner Tote ($258).
Shoes: Your shoes shouldn't compete with the rest of your look, so pick a classic nude pump for an understated finish.
Similar Essentials: Jimmy Choo Agnes Pointed-Toe Patent Pumps ($525); Charles Jourdan Hunter Heels ($199); Boutique 9 Sally Heels ($99).


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NEW ORLEANS (AP) — The Essence Music Festival is dropping the music — from its name, that is.
The festival held in New Orleans every July 4th weekend for the past 18 years has rebranded itself The Essence Festival. Organizers say the change is designed to showcase the event as more than a music festival.
Still, music will remain a focus for the 19th annual festival, which is July 4-7.
The lineup includes more than 30 acts — a number of them Essence veterans. On the roster are Jill Scott, Maxwell, New Edition, Charlie Wilson, Keyshia Cole, LL Cool J and Brandy.
As in past years, concerts will be held at the Superdome while empowerment seminars on health, beauty, careers, education and relationships are held at a nearby convention center.
Copyright 2013 The Associated Press.


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Jump to navigation Jump to search
From Latin superincumbentem, present participle of superincumbere.
superincumbent (comparative more superincumbent, superlative most superincumbent)
- (chiefly sciences) Lying or resting on something else; overlying.
- 1843, Thomas Carlyle, Past and Present, book 3, ch. I, Phenomena
- […] alas, on the contrary, what troops and populations of Phantasms, not God-Veracities but Devil-Falsities, down to the very lowest stratum, — which now, by such superincumbent weight of Unveracities, lies enchanted in St. Ives' Workhouses, broad enough, helpless enough!
- 2004, Richard Fortey, The Earth, Folio Society 2011, p. 87:
- The older Verrucano must have travelled to its present position as it slid and ground its way on the back of the oppressed Lochseiten limestone, which buckled and churned under the superincumbent load.
- 1843, Thomas Carlyle, Past and Present, book 3, ch. I, Phenomena


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Named in honor of George Plimpton's fictional baseball player and subject of a notorious article and April Fools' Day hoax "The Curious Case of Sidd Finch," which was first published in Sports Illustrated on April 1, 1985, Sunday's Finch figures to be a compelling read for handicappers.
Joe Talamo, fast closing in on 1,000 career wins, will be aboard trainer Art Sherman's 5-year-old comebacker who has earned $337,980 from a 5-1-3 record in 16 starts. He will be seeking his first victory in his third start over Santa Anita's Camino Real Turf Course.
His competition includes a pair of runners exiting Santa Anita's Grade II Arcadia Stakes at one mile on turf on Feb. 4: Calimonco and Dewey's Special.
A 7-year-old gelding who had been on the shelf for 23 months, Dewey's Special led into the stretch of the Arcadia before fading to fifth while making his first start for trainer Jeff Mullins. Rafael Bejarano will take over atop the son of Skimming who has posted a career record of 5-2-2 in 15 starts while earning $274,484. He is owned by Moore Racing.
Calimonco had been off for over two months when he ran fourth in the Arcadia which was won by the highly regarded Mr. Commons. Alonso Quinonez will replace injured Victor Espinoza in the saddle. He will carry high weight of 123 pounds.
Calimonco is coming out of four straight Grade II races, twice finishing third, since taking Del Mar's Wickerr Stakes at one mile on turf last July. Trained by John Sadler for breeder Martin Wygod and partners, the Storm Cat offspring has compiled a career record of 4-7-7 in 28 starts for earnings of $303,466.
The field includes the enigmatic Dancing in Silks, who won the 2009 Breeders' Cup Sprint in a 25-1 upset at Santa Anita. The 7-year-old gelding, however, has not finished better than third in nine races since the Grade I stunner. He will make his first start for trainer Anthony Saavedra on Sunday.
The complete field for the Sidd Finch Stakes, with jockeys and weights in post position order: Dancing in Silks, Alex Bisono, 116; Dewey's Special, Rafael Bejarano, 116; Make Music for Me, Martin Garcia, 116; Donato, Agapito Delgadillo, 115; Calimonco, Alonso Quinonez, 123, and Haimish Hy, Joseph Talamo, 116.
The Sidd Finch will be contested as the eighth race on a program of nine races with first post at 12:30 p.m.


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Get Schooled on Mega Man the Board Game
Jasco Games has posted a lengthy playthrough of a bit of its Kickstarted (and Capcom approved) Mega Man board game. It's no joke, and seeing it in action gives us high hopes for the final product.
It's a little dry at the start, but when you're first playing a board game, it take a bit of time to get into the thick of things. Fortunately, since Jasco is explaining its own game, you don't have to worry about learning all the intricacies yourself and can just listen and learn.
As you can see, the tabletop Mega Man adventure combines miniatures, cards and dice to create a system capable of replicating the actual in-game action as closely as possible. There are multiple bosses to take on, and you can choose how you want to approach each playthrough. Defeating bosses gets you their signature weapon, which you can then use to tackle other big bads elsewhere. Jasco's seemingly done a nice job bringing the video game to the tabletop, and despite how much is going on at a given time, the rules don't appear to be overly complicated.
There's still a little bit of time left to back Mega Man The Board Game if you're interested in getting in on the ground floor. We still don't have a definitive release date in sight, but all the prototyping looks great so far, so hopefully we'll all be able to enjoy Jasco's and Capcom's efforts before year's end.


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Instant Marketing necesitaba un nuevo diseño de página web y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 17 diseños de 8 diseñadores freelance.
Nowak Aesthetics, http://www.drnowak.com/
Dr. Eugene J. Nowak, founder of Nowak Aesthetics, is the first San Diego doctor to perform ThermaLipo, the most innovative procedure in cosmetic surgery that produces ultimate results in skin tightening and body contouring. Dr. Nowak has been practicing in the South Bay for the past eight years in Chula Vista and more recently in Eastlake. His practice serves residents throughout San Diego County for dermatological, cosmetic surgery and skin rejuvenation procedures. As a Board Certified Dermatologist who received his Medical Training at MidWestern University, he was appointed to the Sigma Sigma Phi National Honor Society.
Mainly Female but Male as well between 30-70 ans. Anyone who needs some sort of cosmetic surgery, laser or dermatology work done.
Usually all of our websites have 3 columns:
1. column on left hand side for side toolbar and testimonials.
2. middle column, 3 main procedure buttons, Header & then main copy.
3. right hand side, opt-in box in the top corner and filler throughout the column like accreditation's, videos, doctors picture, etc...
4. 'Request a consultation' button must be viewable on front page.
We are not totally set on this format but again this is what we use for the majority of our websites.
It must have and opt-in box in the top right hand corner and room for testimonials and we put a walk-on model on the main page to direct traffic.
To see other designs we have done:
http://www.barrylyckamd.com, http://www.irmocosmeticdentist.com/, http://www.mouldmatters.com is some design that we have done in the past.
We also like the work that this company does http://www.curtisgroup.com


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Scaling Passive and Active Customer-Centric Innovation
Those familiar with my approach to 'social media' will know I think the marcomms element is a happy outcome rather than a primary objective.
The marcomms-first approach - best characterised by the phrase 'using the channel of social media' puts the cart very much before the horse, in my view.
You get efficient, contagious and joined-in with marcomms as an outcome of the really juicy value creation bit of our digitally enabled socially connected lives.
But the juicy bit is better-fitting innovations. (Image courtesy RachelVoorhees)
If you involve the people for whom the product or service is intended you get a product or service which is a better fit with their needs. And that's customer-centric innovation.
The outcome is better for the customer and since better fit equals more sales that means better for the producer (assuming you can maintain margins, of course).
Working with small groups of customers to co-create is not new. Scaling that is.
For example just three or so years ago no one would have written a blogpost to tell the world they were having a cup of tea. Too much effort to go to.
Now, with tumbling technical barriers to entry for anyone to publish their thoughts (no matter how 'trivial' when viewed by traditional criteria) 135k conversations about tea are published in a single month in the UK alone.
All those tweets and Facebook status updates, (forums and blogposts too) reveal how people are using a product, why, where and when, and what they do and don't like about it. And how they'd make it better - if only you gave them a chance.
Gathering what they have to say, analysing it and sharing the resulting data and strategic insight with the right part of any organisation (for action) can be described as Passive Customer Centric Innovation.
You ask no questions. You require nothing more of your customers and potential customers. But from their open publication to their peers and the world, they provide you a low-cost fast track to innovation to mutual advantage.
The second, Active Customer Centric Innovation, takes the same gathered data, identifies (through nodal network analysis) the most appropriate members of communities and invites them into a process of co-creation with key stakeholders. This requires their active engagement; and rewards for their skills and knowledge.
In both cases the key outcome is a better product - one your customers like more.
The marcomms benefits are a happy bonus - and all the better for being derived this way.
- Posted using BlogPress from my iPhone so I may have to tidy it up later ;-)


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Dallas has high hopes for RB
IRVING — Bolstered by his team's draft haul, coaching changes and switch to the 4-3 defense, Jerry Jones believes the Dallas Cowboys' days of mediocrity could be over.
"I'm very optimistic we are better than 8-8, very," Jones said, referring to the team's record the last two seasons. "... We have made some significant ... offensive changes."
One came Saturday when Dallas used its fifth-round pick to select Oklahoma State running back Joseph Randle, who is expected to fortify a running game that was the worst in club history last season.
On the last day of the draft, the Cowboys also picked William & Mary cornerback B.W. Webb in the fourth round and South Carolina linebacker DeVonte Holloman in the sixth.
Randle said in a conference call he was thrilled Dallas picked him, but he expected to go higher.
"I will use it as fuel to my fire," the 6-foot, 200-pound underclassman said. "I will ... remember this day, all the teams that passed me up."
Jones said picking Randle in the fifth was a great value for Dallas and gives it a valuable insurance policy for the oft-injured DeMarco Murray, who has missed nine games since entering the league out of Oklahoma two years ago.
"We've had games we didn't have Murray, and we didn't run the ball as well," Jones said. "We didn't have as good an offense without him.
"So if we have somebody that could possibly step up there and give you the respite you need when you don't have Murray, that's a big deal for us."
Randle said he welcomes sharing the load with Murray. It's all but certain free-agent backup Felix Jones won't return in 2013.
"The NFL is a two-back system now," Randle said. "Guys need other guys to come in, and you don't want to drop the tempo off much."
Randle led the Big 12 in rushing last season with 1,417 yards on 274 carries and 14 TDs. He also caught 28 passes for 224 yards.
More InformationDallas selected four offensive players and three on defense.
Rd. 1 (31): Travis
Frederick, C, Wisconsin
Rd. 2 (47): Gavin Escobar, TE, San Diego State
Rd. 3 (74): Terrance Williams, WR, Baylor
Rd. 3 (80): J.J. Wilcox, FS, Georgia Southern
Rd. 4 (114): B.W. Webb, CB, William & Mary
Rd. 5 (151): Joseph Randle, RB, Oklahoma State
Rd. 6 (185): DeVonte Holloman, OLB, South Carolina
The Cowboys selected only one true walk-in starter: Frederick. Escobar, Williams and Randle provide depth and give the offense flexibility. For a team typically thin by December, improving depth is big. Wilcox, Webb and Holloman are projects.
Although owner Jerry Jones got bashed for drafting down and reaching for Frederick, the trade with San Francisco led to the selection of Williams with the extra third-round pick. Still, there was no help for the aging defensive line, and it remains questionable whether they've finally pushed themselves over a .500 record.
Also a strong blocker, Randle said versatility is his best asset. In that sense, he's a Murray clone.
"One of the reasons we wanted him was because he really mirrors Murray, relative to a complete three-down back," Jones said.


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Mother had these orange poppies planted in her garden by the raspberries and gladiolus. I had a terrible time growing them, so last year I finally gave up and RIPPED them out. I guess they liked it because this year they have grown and bloomed as never before.
Wednesday, June 10, 2009
Labels: Garden, Judy and Bob Petersen family
3 comments:
- Dwight said...
Let them grow, let them spread everywhere; for two or three weeks you'll have magic orange poppies everywhere
- June 10, 2009 at 11:24 PM
- Elizabeth said...
They are so vividly beautiful - you probably have the key to gardening in Washington. Remember sweet woodruff?
- June 11, 2009 at 9:52 AM
- Ann said...
The poppies are beautiful. Last year I planted a handful of mixed flower seeds and this year I have poppies showing up everywhere in reds and oranges. They are such a happy flower. I remember how much Mother loved the poppies.
The beauty of your flowers must be just starting into its season - wish we were there to watch the show.
- June 11, 2009 at 10:05 AM
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The semi-popular Cinema mod for Max Payne 2. Cinema features quite a few changes to Max Payne 2, and to the way it's played. It's hard to describe most of what Cinema offers in words without sounding generic and bland, so it's definitely recommended that you check it out yourself! Cinema aims to provide the player with more of a movie feel, and pulls the task off quite nicely. Miniguns, cinematic feeling scenes -- it's all there!
Only registered members can share their thoughts. So come on! Join the community today (totally free - or sign in with your social account on the right) and join in the conversation.


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LITTLE ROCK — The Christmas Day ice and snow storm that left more than 194,000 Entergy Arkansas customers across the state without power cost the company $55 million to $65 million, the utility said Thursday.
Entergy said it plans to file a rate proposal with state Public Service Commission in March to recover the cost.
The storm that dumped ice and snow across much of the state — up to 15 inches of snow in some areas — caused widespread power outages. Seven counties were particularly hard hit. Gov. Mike Beebe has asked President Obama to issue a disaster declaration for Garland, Grant, Hot Spring, Lonoke, Perry, Pulaski and Saline.
Some Entergy customers in Garland, Hot Spring and Pulaski counties were without power for a week.
The damage estimates included costs for restoring power — more than 4,000 electrical utility workers from across the region traveled to the state to help restore power lines, repairing lines and replacing electrical facilities, Entergy spokeswoman Julie Munsell said.
During the aftermath of the storm, Beebe called out the Arkansas National Guard to help with ambulance service in Pulaski and Faulkner counties, and the governor declared all of Arkansas a state disaster area.
Fourteen National Guard members with seven military ambulances also were called out to assist first responders in Conway, Little Rock and Jacksonville.


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Virtualpsychologist needed a new logo design and created a contest on 99designs.
A winner was selected from 43 designs submitted by 24 freelance designers.
Nugent Estate WorldWide (New)
We are a real estate agency based on the Gold Coast in Australia and we are promoting Surfers Paradise to foreign buyers- particularly United Arab Emirates. We are offering a customised, personalied service that involves establishing and creating relationships with people- to the point of picking them up from the airport and driving them in a limo service to a variety of properties, wining and dining the clients and providing them information about local services such as Bond University, Car dealerships etc
Ideally we are initially targetting United Arab Emirates. We will expand to cover Asia. However, we currently want a clean, crisp, slick corporate image that displays a sense of personalised service along with an exclusivity about the service we offer.
Ideally the logo for Nugent Estate WorldWide should be in black and white with the action colour of red somewhere in it. It must be corporate and slick. You are free to add an appropriate slogan/statement under the logo that you feel best matches our service and the target audience we are aiming to reach. We are really lookin forward to seeing your designs and reading your slogans/statements that form part of our logo. We will give feedback very quickly and look forward to some really great ideas. Remember it is about a personalised customer focused service that is unique and exclusive. Good luck.
Find out how a design contest works or learn more about our logo design services.


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CHAPEL HILL – Chapel Hill people are protesting alongside the NAACP activists in the on-going rallies in Raleigh outside the NC General Assembly.
NC Senator Ellie Kinnaird took part in the protests on Monday where 49 people were arrested.
"These tactics have to take place because the legislature is simply not listening," Senator Kinnaird said.
The democrat is in her 9th term in the state Senate, representing Chatham and Orange Counties.
Sen. Kinnaird
She openly shares she is not pleased with the job the General Assembly is doing.
"We have done such damage to the people who are poor, middle class or marginal."
NC NAACP chapter president Rev. William Barber led an estimated 175 activists outside the state Legislature for "Moral Monday"—speaking out against what they say is a regressive agenda against voting rights, social programs, and education.
It's the third consecutive week of protests in Raleigh and 96 people have been arrested so far—local people included in those numbers.
Chapel Hillians of faith made the trek to Raleigh—representing congregations from the Community Church of Chapel Hill Unitarian Universalist, the United Church of Chapel Hill, and Binkley Baptist Church.
"I joined them last night, I was very proud to do that. These are very solid people. There were lots of ministers, lots of church members, and lots of very committed advocacy workers for various social justice organizations," Kinnaird said. "We aslo have people who are working with-in the Legislature—lobbyists for the NC Justice Center, for the mentally ill, for poor people—who are working day-in and day-out."
The NAACP originally organized the protests—but the movement has grown to include activists from diverse backgrounds.
"It's going to get larger and larger as more people are willing to use those tactics of civil disobedience."
Barber vows that this "wave of civil disobedience" will continue—protesters said they plan to be back next week.
"When they are taken-in by the police and are before protesting in large amounts— people will start to ask, 'Why are they protesting? Why are they there week after week?'' Kinnaird said.
She spoke with protesters outside the General Assembly. Kinnaird then moved inside the building, watching as those who planned to be arrested rallied outside chamber doors while the House of Representatives met.
NC Senator Earline Parmon of Forsyth County, who has attended previous NAACP protests, joined Kinnaird Monday.
"I remember the protests of the 1960s and '70s," Kinnaird said. "It was an exciting time because we felt like we changed the nation. And we feel that these protests can change our state."
Kinnaird says she hopes the protests will spark dialogue for change and have an impact on the next election.
Pictures from Moral Monday Protest:


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shaneb50 necesitaba un nuevo diseño de logotipo y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 30 diseños de 15 diseñadores freelance.
Need a logo for a new e-commerce site selling radio control toys.
We are launching a new web site very soon. It sells radio control cars, trucks, planes, helicopters, boats, and tanks. The site is under development at:
We are happy with the look of the web site, but it needs a nice logo for the upper left. Logo might also be used to watermark youtube videos in the future as well.
We are quite open to any design or colors you might suggest.
We are not sure yet about our current tagline (Your Discount Radio Controlled Toy Source). For now, go ahead and include it if it fits your design. Or even suggest a better one if you'd like.
- The visitor should be able to easily identify the site's proper name (RC Toy Craze) within the logo.
- Logo to be delivered in a web ready jpg, as well as the design file in a vector format of either photoshop (.psd) or paint shop pro (.psp)
Don't want ".com" in the logo.
Descubre cómo funciona un concurso de diseño u obtén más información sobre nuestros servicios de diseño de logo.


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After I swatched a few polishes from OPI's Euro Centrale collection on my blog here last week, my friend asked to borrow OPI... Eurso Euro. So to make sure I was properly sick of it before sending it off on its little journey (sob) I thought I'd nail art it up a bit, with last year's tangerine (ulta3 Tangerine Tango).
I taped the white chevrons, but then I couldn't be bothered waiting for the white to dry to tape off the orange, so I freehanded it and it looked pretty good - I think my freehand skills have definitely improved!
And then before I took it off, I turned it into ALIEN COWS. Because clearly thesis writing has driven me insane.
I am totally in love with OPI...Eurso Euro - it's such a rich blue! Definitely a keeper.
Like this? Click below to let us know!


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Two Maine news anchors resigned together at the end of Tuesday's broadcast after "a longstanding battle with upper management over journalistic practices" including being expected to do politically unbalanced news, the Bangor Daily News reported.
Cindy Michaels and Tony Consiglio announced at the end of WVII-TV's 6 p.m. newscast that it would be their final broadcast together.
"And finally tonight, this will be Tony and my final show together here on ABC 7," Michaels said. "The last six years have been an interesting and enjoyable time for both of us as we have been the longest running news team in Bangor."
Consiglio said "some recent developments have come to our attention though and departing together is the best alternative we can take."
The Daily News reported both anchors were frustrated with the way they were told to do their jobs.
"I just wanted to know that I was doing the best job I could and was being honest and ethical as a journalist, and I thought there were times when I wasn't able to do that," Consiglio said.
Michaels, also the station's news director, cited a "constant disrespecting and belittling of staff" and "a lack of knowledge from ownership and upper management in running a newsroom to the extent that I was not allowed to structure and direct them professionally."
She also said they were "expected to do somewhat unbalanced news, politically." Neither one said which political leaning that was.
Mike Palmer, WVII/WFVX vice president and general manager, told the newspaper he wasn't entirely surprised by the resignations, calling it "unfortunate, but not unexpected." Still, he disputed the characterizations of management's role in the newsroom.
"Upper management is not involved in the daily production of the news. Period," he said.
Neither reporter told anyone prior to the broadcast they were planning to resign.
"We figured if we had tendered our resignations off the air, we would not have been allowed to say goodbye to the community on the air and that was really important for us to do that," Michaels said.


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In college soccer fall is for winning games and spring is for making the necessary adjustments to be able to win the next fall.
The Lipscomb Bisons started their spring season Saturday in Evansville, Ind., tying the University of Kentucky 2-2 and beating Evansville 1-0.
ÃÂââÃÂìàÃÂOur fall season is so condensed that there is not a lot of room for individual player development,ÃÂââÃÂìÃÂàcoach Charles Morrow said. ÃÂââÃÂìàÃÂSpring is a time we can work on deficiencies with players.ÃÂââÃÂìÃÂÃÂ
Goal scoring has not been a major concern for the Bisons, but Morrow admits he wants to spend much of the spring tweaking the defense.
ÃÂââÃÂìàÃÂIf you look at us as a team the last four years the problem hasnÃÂââÃÂìâÃÂât necessarily been goal scoring,ÃÂââÃÂìÃÂàMorrow said.
The Bisons lost Miguel DaSilva, an offensive force, who has returned to his home country of Angola to play professional soccer. But they return Garret Pettis, a first team All-Atlantic Sun performer last season who tied for the team high in goals with eight and points with 19. Nick Bibb, a freshman who got stronger as the season progressed, finished with two goals and four assists for eight points.
ÃÂââÃÂìàÃÂAndrew Chamberlain has played out wide the past couple of years, but we are looking at him up top as well this spring,ÃÂââÃÂìÃÂàMorrow said. ÃÂââÃÂìàÃÂHe has done a great job.
ÃÂââÃÂìàÃÂHe might not be the best finisher on the team, but nobody hits the ball harder. With his personality and the way he plays that playing up top might suit him better.ÃÂââÃÂìÃÂÃÂ
Morrow used several freshmen last year on the back end and expects some of his incoming freshmen to also help bolster the defense.
ÃÂââÃÂìàÃÂI think that our team defense and our backs have to be a point of emphasis,ÃÂââÃÂìÃÂàMorrow said. ÃÂââÃÂìàÃÂI wouldnÃÂââÃÂìâÃÂât say it is an area we have struggled in. But it is an area we can point to and say if we get better in that area we are going to win more games.ÃÂââÃÂìÃÂÃÂ
Kevin Barbar, a center back, was named to the A-Sun All-Freshman Team for 2010. Isaac Pile, recruited as a goalkeeper, also played center back.
ÃÂââÃÂìàÃÂThey both are hard-nosed players who communicate well,ÃÂââÃÂìÃÂàMorrow said. ÃÂââÃÂìàÃÂWe are able to work with them this spring on being better distributors.ÃÂââÃÂìÃÂÃÂ
Coaches who recruited Pile in high school did not project he would be a center back.
ÃÂââÃÂìàÃÂPile covers so much ground,ÃÂââÃÂìÃÂàMorrow said. ÃÂââÃÂìàÃÂHe is so athletic. He plays so hard. Certainly, there are some things to be cleaned up with his play but he is working hard on those things as are we.ÃÂââÃÂìÃÂÃÂ
Morrow has also liked what he has seen from goalkeeper Brent McGee this spring. McGee earned a berth on the A-Sun All-Tournament Team.
ÃÂââÃÂìàÃÂI think the thing he struggled with early on in the fall was his consistency,ÃÂââÃÂìÃÂàMorrow said. ÃÂââÃÂìàÃÂAs the season wore on he did much better. He was playing his best at the end of the season. It is good him to get some playing time outside of training this spring.ÃÂââÃÂìÃÂÃÂ
Written by Mark McGee, Senior Publisher/Director of Media Relations


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Commuters and residents are being warned about the following travel disruptions today, Wednesday, April 23.
A38 Derbyshire - Heavy traffic on A38 Kingsway southbound in Derby at Markeaton Island. Congestion to Palm Court Island.
A38 Derbyshire - Slow traffic on A38 southbound in Little Eaton at Little Eaton Island. In the roadworks area.
A52 Nottinghamshire - Heavy traffic on A52 Brian Clough Way inbound in Nottingham between Bramcote Island and The Qmc Island.
A444 Derbyshire - Slow traffic on A444 Burton Road northbound in Castle Gresley between the Swadlincote Lane junction and the A514 Cadley Hill Road junction.
A453 Leicestershire - Very slow traffic on A453 southbound in Ratcliffe on Soar at East Midlands Airport. In the roadworks area.
A635 Greater Manchester - Heavy traffic earlier on A635 Stamford Street westbound in Stalybridge at the B6176 Rassbottom Street traffic lights junction.


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$140,000 Awarded to Six Projects that Dramatize Science and Technology Themes in Film
Award Committee Includes Matthew Broderick, James L. Brooks, Dr. Stuart Firestein, Robin Swicord, Other Film and Science Luminaries
[New York, NY – April 12, 2012] – TheTribeca Film Institute (TFI) today announced the films that will receive financial and creative support from the TFI Sloan Filmmaker Fund, provided by the Alfred P. Sloan Foundation. This year, out of 121 applicants both in the US and internationally, six projects will be awarded a total of $140,000 and will be recognized at the annual Tribeca Film Festival (April 20- May 1, 2011). Grant recipients will receive year-round mentorship from science experts and members of the film industry with the goal to help their projects at any stage move towards completion. The TFI Sloan Filmmaker Fund awards grants to narrative film projects that dramatize science and technology themes in film or that portray scientists, engineers, or mathematicians in prominent character roles. 2011 also marks the 10th year of the partnership between TFI and the Alfred P. Sloan Foundation, a founding sponsor of the Tribeca Film Festival and TFI.
The winning projects were selected by an Award Committee made up of luminaries in film and science including: Alexis Alexanian (Producer, The Hottest State, Pieces of April, Tadpole); Matthew Broderick (Tony Award-winning actor: Election, Ferris Bueller's Day Off, On Stage: The Producers, How to Succeed in Business without Really Trying); James L. Brooks (Oscar-winning Writer/Director/Producer, How Do You Know, As Good As it Gets, Terms of Endearment); Andrew Fierberg (Producer, Broken English, Fur, Secretary); Dr. Stuart Firestein (Professor of Biological Science & Department Chair, Columbia); Dr. Janna Levin (Professor of Physics & Astronomy, Barnard) and Robin Swicord (Oscar-nominated Writer/Director, The Jane Austen Book Club, Memoirs of a Geisha, Matilda).
Doron Weber, Vice President of Programs at the Sloan Foundation, and select committee members will present the awards at the TFI Awards Luncheon on April 28, 2011 at Riverpark NYC to the following projects: A Birder's Guide To Everything, El Diablo Rojo, A Noble Affair, Photograph 51, Talking Book, and Televisionaries. The projects all emphasize science and technology in their storylines, which focus on subjects such as an extinct duck; predatory squid; Marie Curie; the race to discover the DNA double-helix; and a 1970s computer that reads books out loud for the blind.
"Over the past 10 years, the Alfred P. Sloan Foundation has been an essential part of Tribeca, as well as the film community, by providing funds to help compelling films with science and technology themes to be made," said Jane Rosenthal, Co-Chairman of the Board, TFI. "We look forward to the continued success of the program, including this year's deserving group of grantees."
"We are very proud to celebrate ten years of our pioneering partnership with Tribeca, a partnership that has produced some of the most exciting screenings, readings, panels and film projects in our national science-in film program," said Doron Weber, Vice President, Programs at the Alfred P. Sloan Foundation. "This year's crop of multi-talented, winning filmmakers and their diverse range of stories about science and technology—from comedy to romance, thrillers, historical epics, coming-of-age, drama and biopic—attest to the growing power and appeal of movies that engage with life at the deepest level of nature and our shared humanity."
Selected projects for funding:
A Birder's Guide to Everything
Still reeling from the recent death of his mother, and on the eve of his father's remarriage, teen birdwatcher David Portnoy convinces his friends to join him on a road trip to find what he believes is an extinct duck.
Rob Meyer (Director, Screenwriter)
Luke Matheny (Screenwriter)
Paul Miller (Producer)
El Diablo Rojo
Called down to investigate a mysterious disappearance of fish in the Sea of Cortez, a marine biologist and his team discover a super swarm of "El Diablo Rojo" squid and must risk their lives to prevent a looming ecological catastrophe. Based on true events.
Brent Hoff (Screenwriter, Producer)
Malcolm Pullinger (Producer)
Todd Hagopian (Producer)
A Noble Affair (also a 2008 TFI Sloan Filmmaker Fund recipient)
As Marie Curie is nominated for a Nobel Prize for her groundbreaking work in chemistry, her affair with a married man creates a scandal that ruins her reputation, causes her to flee France, and becomes the obstacle to the prize that will prove her a scientist in her own right.
Anil Baral (Screenwriter, Producer)
Kathryn Maughan (Screenwriter)
Neda Armian (Producer)
Photograph 51
A poignant retelling of Rosalind Franklin's involvement in the controversial race for the double helix in the 1950s, and of the discovery that truly shaped her: the beating of her own romantic heart.
Anna Ziegler (Screenwriter)
Darren Aronofsky (Producer)
Ari Handel (Producer)
Rachel Weisz (Producer)
NOTE: This is an adaptation of Ziegler's Sloan-awarded stage play of the same name.
Talking Book
A technophobic, newly divorced woman falls into the chaotic world of a 1970's hi-tech startup company. She joins forces with an eclectic group of programmers, the visionary Ray Kurzweil, and musician Stevie Wonder to sell the Kurzweil Reading Machine, a computer that reads books out loud for the blind.
Lara Shapiro (Screenwriter, Director)
In an epic battle of wits between two of the 20th century's most influential figures, a genius inventor faces off against a shrewd tycoon for control over a world-changing new technology. Based on the book "THE LAST LONE INVENTOR: A Tale of Genius, Deceit, and the Birth of Television" by Schwartz.
Evan I. Schwartz (Screenwriter)
Jonathan Sheldon (Producer)
Honorable Mentions include:
Radiant, written by Bonnie Kimberly Taylor & Alexander Baxter, tells the story of Marie Curie. It will be produced by Baxter, Laurent Buffi and David Baxter, with executive producer Rose Ganguzza. Sylvie Testud is attached to portray Curie, and Blackwood, written by Lisa Hoppe and Emily Ballou, to be directed by Samantha Lang, and produced by Barbara Grummels and Lizette Atkins - about amateur botanist Georgiana Molloy.
TFI Sloan Filmmaker Works-In-Progress
In addition to financial and year-round ancillary support, TFI Sloan Filmmaker Fund grant recipients will receive exposure to industry executives, financiers and producers during the Tribeca Film Festival at the invitation-only Sloan Works-In-Progress showcase, a presentation of the grant-winning film projects. Five of the six projects in development will have scenes performed by an esteemed cast. The Sloan Works-In-Progress showcase will take place on the morning of April 27th at Helen Millis Theater. Recipients will also have the opportunity to present their projects to industry executives during one-on-one pitch sessions at the TFI Industry Meetings.
In addition to its support of the TFI Sloan Filmmaker Fund and the Works-in-Progress reading, the Alfred P. Sloan Foundation will present a Retrospective Screening & Discussion of the 10th Anniversary of A Beautiful Mind at the Tribeca Film Festival on April 30 at SVA1. Following the screening, a panel discussion about art, science, and math in the film will take place with Ron Howard, Brian Grazer, Akiva Goldsman, Syvlia Nasar, Dave Bayar, Brian Greene, and moderator Ira Flatow (NPR).
About the Tribeca Film Institute:
The Tribeca Film Institute is a 501(c)3 year round nonprofit arts organization founded by Robert De Niro, Jane Rosenthal, and Craig Hatkoff in the wake of September 11, 2001. TFI empowers filmmakers through grants and professional development, and is a resource and advocate for individual artists in the field. The Institute's educational programming leverages an extensive film community network to help underserved New York City students learn filmmaking and gain the media skills necessary to be productive citizens and creative individuals in the 21st century. Administering a dozen major programs annually, TFI is a critical contributor to the fabric of filmmaking and aids in protecting the livelihood of filmmakers and media artists.
For more information and a list of all TFI programs visit http://www.tribecafilminstitute.org/
About the Alfred P. Sloan Foundation
The New York based Alfred P. Sloan Foundation, founded in 1934, makes grants in science, technology, and economic performance. Sloan's program in public understanding of science and technology, directed by Doron Weber, supports books, radio, film, television, theater and new media to reach a wide, non-specialized audience.
Sloan's film program encourages filmmakers to create more realistic and accurate stories about science and technology and to challenge existing stereotypes about scientists and engineers in the popular imagination. In addition to partnering with six of the nation's leading film schools and four Screenplay Development Programs, Sloan has supported such film projects as Future Weather, a coming of age story about a young woman who finds personal meaning in science, starring Lily Taylor and Amy Madigan (now in post-production), and Valley of Saints, which initially received an NYU First Feature Production Award and is one of the first films shot in Kashmir (and now in post-production).
The Foundation has sponsored screenwriting and film production workshops at Sundance, the Hamptons, Tribeca, and Film Independent, and honored feature films such as Obselidia, Agora and Another Earth (forthcoming this summer fromFox). Sloan also partners with Ensemble Studio Theatre (EST), Manhattan Theatre Club and Playwrights Horizons in support of new science plays such as Pidgeon, a drama about Leon Theremin, a Soviet inventor and father of electronic music, which runs as part of the EST/Sloan First Light Festival through April 23.. For more information about the Alfred P. Sloan Foundation please visit www.sloan.org.
Sunshine, Sachs & Associates for the Alfred P. Sloan Foundation
Dave Cirilli: 212.691.2800 or email@example.com
Rubenstein Communications for Tribeca Film Institute
Gina Salese: 212.843.9334 or email@example.com
Tribeca Film Institute
Tammie Rosen: 212-941-2003 or email@example.com


text:
Sep 1st 2007
FLOSS Weekly 19
Hosted by Randal Schwartz, Aaron Newcomb
Junio Hamano, maintainer of the git version control system...
Records live every Wednesday at 12:30pm Eastern / 9:30am Pacific / 17:30 UTC.
Guest: Junio Hamano, maintainer of the git version control system.
Linus doesn't use CVS, or even SVN, he uses git - a version control system he created for keeping track of the vast Linux kernel project. Randal and I talk about the merits of git with its maintainer, Junio Hamano.
Ogg Audio (64kbps mono, 21.39MB)
Thanks to Cachefly for providing the bandwidth for this podcast, and Lullabot's Jeff Robbins, web designer and musician, for our theme music.


text:
Luiz hits out at Brandao head-butt
Paris Saint-Germain defender David Luiz has criticised Brandao after the Bastia striker head-butted Thiago Motta on Saturday.
- Johnson: PSG count cost of ugly Bastia victory
After Bastia's 2-0 loss to PSG, Brandao waited for Motta in the tunnel and clashed with the midfielder, leaving him with blood running down from his nose.
Luiz was disappointed by the behaviour while PSG president Nasser Al-Khelaifi wants Brandao to be banned for life.
Brazil international Luiz said: "As footballers, we have the best job in the world. However, part of that job is to set a good example and especially to the children watching.
"What happened after the game [Brandao head-butting Motta] does not set a good example and that sort of attitude is something that you don't want young children to see.
"It is not part of football. It is something that should not be allowed to happen, not only in football but also in life.
"We need to respect each other and touch the hearts of the people that watch us in a good way, but not in a bad way like this. Our job is so important in terms of setting an example.
"He [Brandao] is not a young guy, he has played for a number of teams in France. He needs to have a bit more respect and also to remember that he is setting an example with his behaviour.
"I don't think that this is the first time that he has tried to fight with someone. It is up to the league to now decide how to punish him. He needs to just concentrate on playing football because he can be a good player."
In the first half of the victory key striker Zlatan Ibrahimovic was substituted after suffering a back injury -- and Luiz is hopeful the Swede is not sidelined long-term.
He added: "Right now, we do not know much about the injury. I hope that he will be able to play in the next game though, because he is obviously a very important player.
"He is a fantastic player and provides a lot, so let's pray [that he recovers].
"Zlatan was one of the players who clearly explained PSG's plans for the future to me and he helped to convince me to come here. He is a great player, but he is also extremely humble and that helps him keep his feet on the ground. I like this quality.
"We are very lucky. Everybody tries to make the most of their career because we know that in a short space of time, it is all over. It is important in life to keep your character and your personality and Ibrahimovic has done that."
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[contentblock id=46]
LED Wall Pack Retrofit Kit 30w – 60w SS Yoke
LED Corporation LED Wall Pack Retrofit Kit Extra Small Solstice Plate 30w – 60w SS Yoke is UL listed and DLC and designed to retrofit into almost any HID fixture using custom fabricated brackets and plates for easy plug and play installation. We can articulate our units and offer innovative optics to deliver light precisely where needed. Dark Sky Compliant. The LED Wall Pack Retrofit Kit 30w – 60w SS Yoke comes with an Energy Saver program that is accessed via a Two way switchable power options on board.
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text:
2 women, 1 man killed when out-of-control Jeep crashes at Massachusetts auto auction
Two women and one man died and several others were injured Wednesday when a Jeep struck several people at an auto auction in Massachusetts.
The crash happened just after 10 a.m. at the Lynnway Auto Auction in Billerica, about 90 minutes after an auction was scheduled to begin.
A 2006 Jeep Grand Cherokee, driven by a man in his 70s, was in one of the facility's eight lanes when it suddenly accelerated and struck the victims. Two women and one man were killed.
Lahey Hospital and Medical Center said it was treating six people injured in the crash, while Lowell General Hospital said it had three others.
Two victims suffered life-threatening injuries, and eight others suffered serious injuries, District Attorney Marian Ryan said.
Woody Tuttle, an auto auction employee, said the driver of the Jeep was trying to avoid hitting other vehicles when it struck several people who were standing between the lanes.
"I heard a screeching of tires, and, I believe, a Jeep Cherokee went flying by me. In avoiding the cars, whoever was driving this vehicle hit several people," Tuttle said.
The Jeep then crashed through the side of the building.
"(The driver) avoided the cars, and went on to hit the people who were standing between the cars," Tuttle said. "Three (men) were on the ground being tended to. There was a woman who was crying, but she was standing up, and I saw two men on the ground who appeared to be dead."
Randy Miller, who was attending the auction said it appeared the vehicle was traveling about 40 mph.
"We heard a bang or an explosion. It was almost like a bomb. The whole place just went silent," Miller said. "There were people just lying on the ground -- a horrific, crazy, tragic situation."
Massachusetts State Police said there were "multiple victims," and more than 12 ambulances were called to the scene.
"At this point, there is no evidence or information to suggest the incident was caused by an intentional or terrorist act. All evidence and information at this time suggests an accidental cause," State Police said.
The building has been evacuated.
"We are very saddened by today's events at the auction. Our thoughts and prayers go out to the individuals and families affected," Lynnway Auto Auction posted on its Facebook page.


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10.11.2012 – 15:03
Phase 2 Results Show INCIVO® (telaprevir), in Combination With Peginterferon Alfa and Ribavirin, is Effective in Treating Patients Co-infected With Genotype-1 Chronic Hepatitis C Virus and HIV
Boston, Massachusetts (ots/PRNewswire)
- Study presented at American Association for the Study of Liver Diseases 2012 shows high sustained virological response (SVR) in HCV/HIV co-infected patients
receiving INCIVO(R) (telaprevir)-based regimen -
Janssen Infectious Diseases-Diagnostics BVBA (Janssen) today presented results from a new phase 2 study which shows that an INCIVO(R) (telaprevir)-based regimen was effective in achieving a sustained virological response at 24 weeks (SVR24) in patients co-infected with both genotype-1 chronic hepatitis C virus (HCV) and HIV (HCV/HIV) compared to patients receiving a placebo with the standard HCV treatment, peginterferon alfa and ribavirin (74 vs. 45 percent).[1]
An estimated 130 to 210 million people are infected with HCV worldwide[2], with HCV/HIV co-infections averaging about 40 percent of HCV patients in Europe.[3] People co-infected with HCV/HIV have more rapid fibrosis progression and liver disease than patients with HCV alone.[3] Chronic HCV infections can lead to end-stage liver disease, which is a major cause of death in HCV/HIV co-infected patients.[3] Despite the added health consequences of co-infection, only a small proportion of HCV/HIV co-infected patients receive treatment for their hepatitis.[3]
"The new data further demonstrate the potential efficacy and safety of telaprevir when used in combination with peginterferon alfa and ribavirin in HCV/HIV co-infected patients. New effective treatment regimens are particularly important for this patient group due to their high risk of rapidly developing liver complications," said investigator, Kenneth E. Sherman, M.D., of the University of Cincinnati College of Medicine.
The phase 2 study was a two-part randomized, double-blind, placebo-controlled, parallel-group, trial of telaprevir with a standard HCV treatment combination of peginterferon alfa and ribavirin (PR) in previously untreated patients with genotype-1 chronic HCV/HIV co-infection. The study treated a total of 60 HCV/HIV co-infected patients who did or did not receive a concomitant stable antiretroviral therapy (ART) regimen.[1] During the study, no patients receiving a telaprevir-based regimen experienced HIV RNA breakthroughs and their CD4 T-cell count percentage remained unchanged.[1]
The safety and tolerability of a telaprevir-based regimen for treating HCV in HCV/HIV co-infected patients were comparable to that previously observed in HCV mono-infected patients.[1] Adverse events that occurred more frequently (>10 percent difference) in HCV/HIV co-infected patients receiving telaprevir and PR compared to HCV/HIV co-infected patients taking PR alone included pruritus (itchiness), headache, nausea, rash and dizziness.[1]
"Now that ART for people living with HIV has improved so vastly over the years in controlling their HIV, it has become increasingly important to address the consequences of chronic HCV infection in patients co-infected with HCV/HIV. Janssen remains committed to addressing the unmet needs of patients and increasing the availability of new treatment options for patient groups who have been largely underserved until now", said Alessandra Baldini, Medical Affairs Director, Janssen.
The analysis of the data from this study, AASLD Abstract Final ID: 54, will be submitted for peer-review publication.
Additional telaprevir data being presented at AASLD (http://www.aasld.org/lm2012 )includes:
- Non-inferior SVR rates in previously untreated genotype-1 HCV patients receiving a telaprevir-based regimen twice-daily versus every eight hours.[4] Abstract (Final ID: LB-8) - Telaprevir Global Early Access Programme efficacy and safety data regarding treatment among genotype-1 HCV patients with severe fibrosis or compensated cirrhosis.[5]Abstract (Final ID: LB-15) - Factors predictive of anemia development in treatment-experienced patients receiving telaprevir plus PR in the REALIZE trial.[6] Abstract (Final ID: 771) - Rate of disappearance of telaprevir-resistant variants using clonal and population sequence data from Phase 3 studies.[7] Abstract (Final ID: 756) - Evaluation of liver and plasma HCV RNA kinetics and telaprevir levels in genotype-1 HCV patients treated with telaprevir using serial fine needle aspirates.[8]Abstract (Final ID: 215) - Deep sequencing of the HCV NS3/4A region confirms low prevalence of telaprevir-resistant variants.[9] Abstract (Final ID: 1091)
About INCIVO(R)
INCIVO(R) (telaprevir), in combination with peginterferon alfa and ribavirin, is indicated for the treatment of genotype-1 chronic HCV in adult patients with compensated liver disease (including cirrhosis) who are treatment naive, and who have previously been treated with interferon alfa (pegylated or non pegylated) alone or in combination with ribavirin, including relapsers, partial responders and null responders.[10] INCIVO(R) is a small molecule, selective inhibitor of the HCV serine protease, and a member of the new class of medicine for the treatment of genotype-1 chronic HCV, direct acting antivirals (DAAs). Unlike previous treatments, DAAs act directly on viral enzymes and prevent the virus from replicating. INCIVO(R) was approved by the European Commission on 19 September 2011.
Telaprevir was developed by Janssen Infectious Diseases - Diagnostics BVBA, one of the Janssen Pharmaceutical Companies, in collaboration with Vertex Pharmaceuticals (Vertex) and Mitsubishi Tanabe Pharma Corporation (Mitsubishi Tanabe Pharma). Janssen has rights to commercialize telaprevir in Europe, South America, Australia, the Middle East and certain other countries. Vertex has rights to commercialize telaprevir in North America where it is being marketed under the brand name INCIVEK[TM]. Mitsubishi Tanabe Pharma has rights to commercialize telaprevir in Japan and certain Far East countries where it is being marketed as TELAVIC(R).
Important Safety Information
Please see full Summary of Product Characteristics or visit http://www.emea.europa.eu for more details.
The overall safety profile of telaprevir is based on the Phase 2/3 clinical development programme containing 2,641 patients who received a telaprevir-based regimen. In clinical trials, the incidence of adverse events of at least moderate intensity was higher in the telaprevir group than in the placebo group (both groups receiving peginterferon alfa and ribavirin). The most frequently reported adverse reactions (incidence greater than or equal to 5.0%) of at least grade 2 in severity were anemia, rash, pruritus, nausea, and diarrhoea during the telaprevir treatment phase, and the most frequently reported adverse reactions (incidence greater than or equal to 1.0%) of at least Grade 3 were anemia, rash, thrombocytopenia, lymphopenia, pruritus, and nausea.[10]
Rash events were reported in 55% of patients with a telaprevir-based regimen compared to 33% of patients treated with peginterferon alfa and ribavirin only and more than 90% of rashes were of mild or moderate severity. Severe rashes were reported with telaprevir combination treatment in 4.8% of patients. Rash led to discontinuation of telaprevir alone in 5.8% of patients and 2.6% of patients discontinued telaprevir combination treatment for rash events compared to none of those receiving peginterferon alfa and ribavirin.[10]
Hemoglobin values of < 10 g/dl were observed in 34% of patients who received telaprevir combination treatment and in 14% of patients who received peginterferon alfa and ribavirin. In placebo-controlled Phase 2 and 3 trials, 1.9% of patients discontinued telaprevir alone due to anemia, and 0.9% of patients discontinued INCIVO(R) combination treatment due to anemia compared to 0.5% receiving peginterferon alfa and ribavirin.[10]
About HCV
HCV is a blood-borne infectious disease that affects the liver.[11,12] With an estimated 130-210 million people infected worldwide,[2] and three to four million people newly infected each year, HCV puts a significant burden on patients and society.[13] Estimations indicate that HCV caused more than 86,000 deaths and 1.2 million disability-adjusted life-years (DALYs) in the WHO European region in 2002 (latest data available).[14] Chronic infection with HCV can lead to liver cancer and other serious and fatal liver diseases.[15] About one-quarter of the liver transplants performed in 25 European countries in 2004 were attributable to HCV (latest data available).[14] The previously accepted standard treatment for HCV was peginterferon alfa combined with ribavirin,[16] however this only cleared the virus for 40-50 percent of genotype-HCV patients.[16,17]
About Janssen
At Janssen, we are dedicated to addressing and solving some of the most important unmet medical needs of our time in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Driven by our commitment to patients, we develop innovative products, services and healthcare solutions to help people throughout the world. Janssen Infectious Diseases - Diagnostics BVBA is part of the Janssen Pharmaceutical Companies of Johnson & Johnson. Please visit http://www.janssenrnd.com for more information.
1) Sulkowski MS, Sherman KE, Soriano V, et al. Telaprevir in Combination with Peginterferon Alfa-2a/Ribavirin in HCV/HIV Co-infected Patients: SVR24 Final Study Results. 2012. American Association for the Study of Liver Diseases (AASLD) Abstract (Final ID: 54). 2) European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Management of hepatitis C virus infection. Journal of Hepatology. 2011; 55: 245-264. 3) WHO EUROPE. Management of Hepatitis C and HIV co-infection - Clinical protocol for the WHO European Region. Available at: http://www.euro.who.int/data/assets/pdf_file/0008/78146/E90840_Chapter_6.pdf. Last accessed September 12, 2012. 4) Buti M, Agarwal K, Horsmans Y, et al. OPTIMIZE Trial: Non-inferiority of twice-daily telaprevir versus administration of every 8 hours in treatment-naive, genotype 1 HCV infected patients. 2012. American Association for the Study of Liver Diseases (AASLD) Abstract (Final ID: LB-8) 5) Colombo M et al. Treatment of Hepatitis C Genotype 1 Patients with Severe Fibrosis or Compensated Cirrhosis: The International Telaprevir Early Access Program. 2012. American Association for the Study of Liver Diseases (AASLD) Abstract (Final ID: LB-15) 6) Zeuzem S, DeMasi R, Baldini A, et al. Factors predictive of anemia development in treatment-experienced patients receiving telaprevir (T;TVR) plus peginterferon/ribavirin (PR) in the REALIZE trial. 2012. American Association for the Study of Liver Diseases (AASLD) Abstract (Final ID: 771). 7) Sullivan J, De Meyer S, Haseltine E, et al. Rate of disappearance of telaprevir resistant variants using clonal and population sequence data from Phase 3 studies. 2012. American Association for the Study of Liver Diseases (AASLD) Abstract (Final ID: 756). 8) Talal A, Dimova R, Zhang E, et al. Evaluation of Liver And Plasma HCV RNA Kinetics And Telaprevir Levels In Genotype 1 HCV Patients Treated With Telaprevir (TVR) Using Serial Fine Needle Aspirates (FNA). 2012. American Association for the Study of Liver Diseases (AASLD) Abstract (Final ID: 215). 9) Dierynck I, De Meyer S, Thys K, et al. Deep Sequencing of the HCV NS3/4A Region Confirms Low Prevalence of Telaprevir-resistant Variants Both at Baseline and End of Study. 2012. American Association for the Study of Liver Diseases (AASLD) Abstract (Final ID: 1091). 10) Incivo(R) Summary of Product Characteristics, updated 2011 11) Simin, M et al. Cochrane systematic review: pegylated interferon plus ribavirin vs. interferon plus ribavirin for chronic hepatitis C. Alimentary Pharmacology & Therapeutics. 2007; 25(10):1153-62. 12) Centres for Disease Control and Prevention. Hepatitis C FAQs. [cited 2009 Dec 17] Available from: http://www.cdc.gov/hepatitis/C/cFAQ.htm#transmission 13) WHO. State of the art of vaccine research and development. Viral Cancers. Available from http://www.who.int/vaccine_research/documents/Viral_Cancers.pdf 14) Muehlberger, N et al. HCV-related burden of disease in Europe: a systematic assessment of incidence, prevalence, morbidity, and mortality. BMC Public Health. 2009; 9(34):1-14. 15) Lang K, Weiner DB. Immunotherapy for HCV infection: next steps. Expert Review of Vaccines 2008;7(7): 915-923. 16) McHutchison, J et al. Peginterferon Alfa-2b or Alfa-2a with Ribavirin for Treatment of Hepatitis C Infection. N Engl J Med. 2009; 361:580-93. 17) The Hepatitis C Trust. Treatments: Potential New Drugs. [cited 2010 Feb 20] Available from: http://www.hepctrust.org.uk/treatment/potential-new-drugs/Drugs+that+target+the+virus
MEDIA Ronan Collins, +44(0)7876-257-746
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