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In Chicago, A Test Of Wills Over A Budget Deficit
Part 1 of a 6-part series
In Washington, congressional leaders and the White House are in a financial fight that's being watched around the world. But outside the Beltway, in cities large and small, mayors are grappling with their own economic challenges.
In Chicago, Mayor Rahm Emanuel is no stranger to tough negotiations. And, fresh from his second stint as a White House adviser, that's where he finds himself now.
Emanuel's predecessor, Richard Daley, left him a daunting financial hole. Chicago faces a $600 million budget gap next year — not to mention the $31 million deficit this year. As part of the solution, Emanuel decided that more than 600 city workers should be laid off.
"My duty as mayor is to protect our city's taxpayers and be their voice — not to protect the city's payroll," he says.
And the fight was on.
Everything On The Table
This week, union leaders said if Emanuel wants to cut jobs, maybe he should look to middle managers who fill the offices of City Hall.
"We think before you outsource anything, or before you look to cut anything or look for anything else from your workers, you should at least be managing the city in a way the taxpayers really demand — and that's [as] efficiently as possible," says Jorge Ramirez, the head of the Chicago Federation of Labor, one of two umbrella groups representing about 8,000 city workers.
Under the budget created by Daley, city workers agreed to several furlough days in order to prevent layoffs. But that concession expired in June, and Daley did not negotiate an extension before leaving office.
In his news conference, Emanuel shot back at the union leaders: "No part of the budget — any part of the budget — from the mayor's office, to work rule reforms and everything between those boundaries is not off limits, it's on limits."
Meaning everything is on the table. While the mayor was clearly miffed, this was not a raucous Chicago-style smackdown — not yet. Things are still fairly civil, but maybe not for long.
Roosevelt University analyst Paul Green says Emanuel was elected with 55 percent of the vote in part because of his reputation for making tough decisions. And he says that when it comes to Chicago's deficit, Emanuel may have to stop negotiating and make some tough calls.
Economic Snapshot: Chicago
NoteUnemployment numbers are seasonally adjusted.
The city of Chicago is in Cook County, Ill. Per capita personal income is for 2009. It is defined as income received by persons from all sources, including but not limited to the sum of wage and salary disbursements, supplements to wages and salaries, rental income, and personal dividend income.
"Compromise is not going to get him to where he needs to go," Green says. "He's got to take some really hard positions eventually, and I think he's going to be dealing with a lot of angry people. There is no way to sugarcoat this: There are really difficult budget choices to be made, and you can't finesse it."
Finding New Ways To Save Money
Chicago is a world-class city, with a vibrant downtown, Fortune 500 businesses and major league sports teams, all set on the shores of Lake Michigan. But like many other cities, the recession dealt Chicago a harsh blow — one for which it wasn't prepared.
"Chicago entered the Great Recession with no reserves, with an operating deficit, and with no long-term plan on how to get through this financial challenge," says Laurence Msall, president of the Civic Federation, a local government watchdog group.
That challenge is expected to add up to a massive $600 million to $700 million deficit next year.
Msall says Emanuel is on the right track. He used an executive order to create a long-range financial planning process, and the budget is one of his top priorities. For the past couple of weeks, the mayor has held news conferences — showcases, of sorts — to detail how the city is working to shave costs.
At one of the city's water filtration plants, the Jardine plant, department heads say they're changing "business as usual" procedures. Water department officials say instead of tearing up streets to repair sewers, they'll install more liners that extend the life of the city's sewers; two other departments plan to merge, and the city will reduce the size of its vehicle fleet and install Zipcar technology so workers share cars.
Emanuel says the group came up with initiatives to save $14 million.
"I asked everybody ... to go through the budgets, not get stuck to old ways, but ask some fundamental questions, going line by line, which is, is this the best way to deliver this service?"
Labor leaders say the efficiency report they've offered Emanuel could save Chicago as much as $242 million. It's a familiar theme — dueling ideas about what to cut and how.


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Editors' note: Since the Optimus V is so similar to the Optimus S, in this review we'll focus on what sets the Optimus V apart. For more design details, please read our LG Optimus S review.
We thought the LG Optimus U would be the last of the LG Optimus line of handsets (see the LG Optimus T, the Optimus S, the Vortex, and the Optimus M), but it appears we were wrong. Virgin Mobile has released its very own Optimus handset, appropriately named the LG Optimus V. As you might expect, the Optimus V is practically identical to the Optimus S, with similar features and specifications. It does offer a few minor differences over the LG Optimus S, which we'll review here. The LG Optimus V is very competitively priced at only $149.99 without a contract.
The LG Optimus V is really the spitting image of both the Optimus S and the Optimus U. It's quite slim, just like the other phones, at only 0.52 inch thick, so it's very pocket-friendly. It has a nice soft-touch finish all around, and the 3.2-inch touch-screen interface is just as colorful and intuitive.
The only design differences are cosmetic. Instead of slate gray, the Optimus V is pure black. It has the same button placement as the Optimus U, with the Menu key first and the Home key second, followed by the Back and Search keys. The Optimus V has a default home screen with Virgin Mobile colors (a gradient of red to black) along with a few built-in Virgin Mobile apps.
Otherwise, the Optimus V has a fairly stock Android interface, with shortcuts to the phone dialer, the main menu, and the Web browser on the home screen. The Optimus V does have the Swype keyboard built in. This lets you quickly enter text by sliding your finger in one continuous motion over the screen keyboard. Of course, you can always switch to the default multitouch Android keyboard if you prefer.
The LG Optimus V ships with Android 2.2, but it should be upgradable to Android 2.3 in the future. Still, Android 2.2 is a great operating system for an entry-level smartphone. Some of its features include voice dialing over Bluetooth, app sharing, and phonebook integration with Facebook and Twitter contacts. Do note that it can't play Flash video in the browser even though the firmware technically supports it--the Optimus V just doesn't have the hardware for it. You can still play Flash video, but only with YouTube and third-party apps.
The rest of the features are impressive as well. It has 3G in the form of EV-DO Rev. A, stereo Bluetooth, Wi-Fi, and GPS. The GPS can be used with a variety of location-based apps, like Google Maps, Latitude, Places, and Scvngr, a scavenger hunt-inspired app. Unlike most of the other Optimus handsets, the Optimus V does not have mobile hot-spot capabilities, which is a disappointment.
Of course, the LG Optimus V also comes equipped with Google apps and features, such as a Google search bar complete with voice search, Google Talk, Gmail and Google Calendar sync, and YouTube. Virgin Mobile included a few third-party apps too, like Where, the aforementioned Scvngr, Twidroyd, Poynt, AirG Chat, and Virgin Mobile Live, an app that lets you stream music from Virgin Mobile Festival artists for free. As this is a Virgin Mobile phone, you'll also have a My Accounts app to keep track of your minutes with.

subset: commoncrawl


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12 Genuine Ways to Earn Extra Money For Christmas
As Christmas is just a hop, skip and a jump away, many are seriously brainstorming for extra ways to earn cash or gifts for Christmas. Every little thing helps when you have to buy for not only your closest friends and family, but also your co workers, nieces, nephews, aunts, uncles and on and on… Christmas can certainly take a bite out of your budget, so every little bit helps. Of course, you're not gonna get rich or make a full time living from this you know. If you're looking for more lucrative ways to earn, you may want to turn to this section of job leads instead.
Reward sites have become a very popular method of making money for a lot of people these days.
Reason being is, they offer a lot of various ways you can earn money like taking online surveys, searching the web, referring friends, playing games, watching videos and more.. These are quick and simple resources where you can put an extra few bucks in your pocket or just simply provide some extra gifts to your friends.
Here is a great list of ways to not only get your hands on some extra cash, but on some prizes too. These are also great places to get grocery coupons.
1. Swag Bucks – Using these methods is the fastest way to earn – Take the daily poll, Install the toolbar on your browser,look through all the special offers,play the games,use the search function multiple times per day,watch videos (Huge selection). Make sure you hit the daily goal (It's an extra 10% earning.) Using these methods can get you roughly 200 swag bucks per day.
2. UniqPaid – SCAM BEWARE
3. Mr Rebates – $5 signup bonus. Perfect for making money during the Christmas holiday. Much like ebates. Over 2,400 different cash back stores such as Amazon, Disney, Home Depot, Priceline, Sephora, Tigerdirect, WalMart & more.. Earn cashback by shopping! Refer a friend and earn 20% off of all their purchase as well. Minimum payout is $10.
Freebie Places – Get lots of freebies, free tester gifts, coupons and more..
1. Publishers Clearinghouse – Major Sweepstakes – YES it's real! Tons of money giveaways and big cash prizes.
2. 3000 Free-Goodies – Free samples, coupons, free food..
3. 2000 Freebies – Freebies – Lots of free samples, coupons on groceries, restaurants, software and more…
4. Freebie King – Lots of Christmas coupons being offered right now. Get money off Sunglasses, food items, lots of sweepstakes. Just subscribe to receive multiple offers.
5. Sun Sweeps – Must be US resident, 21 or over. Always having large sweepstake prizes (up to $50K) so make sure to check frequently.
6. Refund Sweeper – Get tons of free coupons.. $1 off baby items,groceries, Medicine, mail in rebates and more…
Online Reward Sites with Surveys & More…
1. My Points – Must be 18 or older. Canada or USA Residents only. Very reliable survey company (among other things). $10 minimum cashout. Earnings are based on points which can be converted. Many ways to cashout including PayPal, gift cards, Red Cross Donation, air miles or Visa prepaid card. Ways to earn are online surveys, Reading emails,Shopping, offers games, easy points, referrals, book travel, printing coupons and online search.
2. Unique Rewards – $5 signup bonus. US, UK and Canada residents only. Earn cash or points on surveys. Also earn additionally on Cash offers, cash back on shopping, paid to click, reading emails, watching videos, listening to the radio and referrals.. $20 cashout minimum but you can earn it pretty fast with this site.
3. Quick Rewards – Quick rewards as the name indicates is a reward site. Surveys,
Visiting Websites, Shopping, Completing Offers, Watching Videos, Playing Games, Print Grocery Coupons, Listening to Music, Trivia, Referring Friends.


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Celebrity Kids at Parties
15 Ways Celebrity Tots Party in Style!
15 Ways Celebrity Tots Party in Style!
Balloons, cake, gifts, the occasional red carpet . . . what's not to love about a good party when you're a famous kid? Whether they're accompanying their parents to a film festival or sporting sunnies at a pool party, one thing's for certain, these lil ones know how to party like rock stars! Check out some of the sweetest little famous faces celebrating birthdays, product launches, and more with their friends and family. Then, if you can't get enough celebrity kid fun, cast your vote for the Best-Dressed Celebrity Kid of 2012!
Source: FameFlynet and Getty


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The ring spanner end has a 12-point OGV® profile angled at 15°, maximising the contact surface with the nut for a longer lifetime. The open end is angled at 15° from the handle axis.ISO 691 - ISO 1711-1 - ISO 3318 - ISO 7738 - DIN 3113.
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Last month, on the way home from my nephew's baptism party, my husband said, in a shocked tone, "That was the best family party we have ever been to.The kids were amazing and had so much fun! I wasn't even stressed out or worried about the kids getting over stimulated. What just happened?"
Throughout the rest of our 3-hour car drive home, we discussed what had made this particular party so much fun. We also compared it to other parties that were not nearly so pleasant. Parties that ended in tears and meltdowns, parties that we had to leave because one of our kids was just too over stimulated to handle.Parties that I swore would be the last I attended because things had gone so poorly for Danny and/or Charlotte.
We realized this particular party in September had been so successful because we have some family members who are 100% committed to making family gatherings pleasant for my two SPD kids.
I'm over at Hartley's blog today, so click here to read more......
And if you are interested in reading my post about scooter board activities, click here.


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Nourish Nugget: Isaiah 55:10 – God Gave us Sprouts!
Published by Rashida Serrant-Davis DWS
Driving to work one morning on the M6, then WSET Advanced Certificate student Rashida Veronique Serrant turned a corner - literally and figuratively! As she rounded a bend in the roadway on the South Island of New Zealand to enter Gibbston Valley and laid eyes on the sun-drenched vineyards of Chard Farm Winery on the other side of the Kawarau River gorge, Rashida knew what she wanted to do with her professional life. Fast forward 15 years, through the Wine & Spirit Education Trust Diploma program (hence the DWS), opening and closing wineLIFE Wine Shop, and experience in wholesale, retail and sommelier work with wine, Rashida shifted gears and launched Really Nourish Movement, through which she educates about food and advocates for food empowerment for all. The first step she took on her way to her current, excellent state of health and the beginning of Really Nourish was to listen to God and feed herself a lot less sugar and refined starch. Her motivation: Donating a kidney to her father. It was not an Atkins thing, if that's what you're thinking. She still ate carbs, just what she had learned to be better ones. She continued to indulge in animal products, did not reduce her fat intake on purpose, but reduced her intake of free sugars to less than 25g a day. During that first month, it was like weaning off of hard drugs! She had headaches from time to time and often found herself to be quite cranky. Eventually, as her body grew accustomed to the change, she achieved two consecutive days with no free sugars at all – no juice, no sugar sweetened foods or beverages. She was already off of refined starches. She very rapidly lost exactly 20 lbs by the end of those 30 days. Her theory is that much of that was inflammation in my body. Much of the excess weight that people carry is indeed inflammation, and excess amounts of sugar are known to contribute to that. Nonetheless, as we also are learning, sugar is not the lone culprit in the obesity and metabolic disease epidemic. Rashida witnessed this for herself. After losing that 20, going down from 212 lbs to 192 lbs, she hit a plateau. All summer long she stayed at that pesky 192. She did yoga and Pilates almost daily and never went back to my normal American high sugar, high refined starch, processed food diet. But still, Rashida's 192 lbs remained steadfast. Then, in October of that year, with some encouragement from the Lord, the documentary Cowspiracy and Chronixx, Rashida decided to give up all things carnivorous. That's when the 192 started to tick downward again. By the the following March, she was 160. She was ready now to donate her kidney to her dad. More than a year later, I am 155 at the start of the pregnancy that will bring forth my third child by the grace of God. View all posts by Rashida Serrant-Davis DWS


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This level provides coverage for equipment for manufacturer defects that can result in the loss of operation. The Mack Worldwide Warranty will cover parts and labor at no additional charge.
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Aug. 10, 2006
2006-07 Santa Clara Women's Tennis Schedule
2006-07 Santa Clara Men's Tennis Schedule
SANTA CLARA, Calif. - The Santa Clara University men's and women's tennis teams announced their schedules for the 2006-07 season today. The women open up the fall slate with a trip to Fresno to participate in the Bulldog Classic from Sept. 22-24, while the men begin their season on the Mission Campus, hosting the Santa Clara Bronco Classic at the Degheri Tennis Center from Oct. 6-8.
Coached by George Husack, who enters his fifth season in charge of the men's tennis team, the Broncos will play in four tournaments in October, before beginning the 2007 schedule in January with the San Diego State Hidden Dual Tournament (Jan. 13-14). The home schedule opens up with a pair of team matches on Jan. 20 against UC Santa Cruz and UC Davis. The Broncos will also welcome top opponents like Boise State (Jan. 28), Oregon (Feb. 17), UC Santa Barbara (Feb. 19), Cornell (Mar. 23) and Brigham Young (Mar. 27).
Alumni day for the men's tennis program will take place on Mar. 30, when Husack's team squares off against Ivy League power Harvard. Home WCC matches include Gonzaga (Feb. 16), San Francisco (Feb. 22) and Portland (Mar. 2). On February 3, Husack's squad will face one of its biggest challenges as it travels to Malibu to face the defending NCAA Champion Pepperdine Waves. The Broncos conclude their home schedule with a Pro-Am Invitational at Degheri Tennis Center on Apr. 28.
"The schedule is set up to play as many ranked opponents as possible to give us an opportunity to be nationally ranked and make the NCAA Tournament," said Husack. "We are happy to have 16 home matches this year because we play very well at home. We also want to improve our play on the road and we have a number of challenging matches on the road to help us accomplish that goal. Overall, we are just looking forward to getting started."
For the women, led by third-year coach Damon Coupe, the fall schedule consists of six tournaments, including the ITA Regionals from Oct. 20-23. After the winter break, the Broncos open up their team schedule with three straight road contests at UC Santa Barbara (Feb. 3), Pacific (Feb. 10) and UC Davis (Feb. 13). The team then plays its first home match against WCC rival Gonzaga on Feb. 17, followed by conference matches against Saint Mary's (Feb. 18) and San Francisco (Feb. 23), also at the Degheri Tennis Center. Overall, the women play nine matches at home in 2007 and 11 on the road.
"This is by far the toughest schedule the women's program has ever had," said Coupe. "The players want to play against the best and so do the coaches. We look forward to competing hard all season."
The WCC Championships for both teams will take place from Apr. 20-22 in Malibu. Last year, the men took fourth in the WCC, while the women finished seventh.


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Fifty-nine Big 12 golfers have been named to the 2013 Academic All-Big 12 Golf Teams, the conference office announced.
On the men's side, Daniel Wood (Kansas State) was nominated with a 4.00 grade point average. For the women, Taylor Schmidt (Oklahoma), Alexandra Bonetti (TCU) and Kim Kaufman (Texas Tech) are 4.0 GPA nominations.
Curtis Yonke (Kansas State) becomes a three-time Academic All-Big 12 first team honoree. Five members of the women's team are also three-time first team selections: Hanna Roos (Kansas State), Madison Pressel and Haley Stephens (Texas), and Gabby Dominguez and Kaufman (Texas Tech).
The Iowa State men led all teams with five first team honorees. ISU's quintet was matched by Texas Tech in overall selections as both institution's represented with five total members. Texas and Texas Tech paced the women's honorees with five first team selections. Between both teams, Texas Tech's 10 selections was the highest.
A total of 47 student-athletes earned first team recognition (19 men, 28 women), while 12 golfers comprise the second team (seven men, five women).
First team members consist of those who have maintained a 3.20 or better GPA while the second team selections hold a 3.00 to 3.19 GPA.
To qualify, student-athletes must maintain a 3.00 GPA or higher (either cumulative or the two previous semesters) and must have participated in 60 percent of their team's scheduled contests. Freshmen and transfers are not eligible in their first year of academic residence. Senior student-athletes who have participated for a minimum of two years and meet all the criteria except percent of participation are also eligible.


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Dispatch: The Algerian exception?
Our friend Abu Ray, a journalist covering North Africa, sent in this dispatch from Algeria where he was to cover the recent parliamentary elections, in which the ruling FLN won against expectations that Islamist parties would do well, as they have done in neighboring Tunisia and Morocco. The Islamists and many others have decried widespread fraud and the turnout was very low.
For some of us journalists, the Arab Spring meant discovering French colonial architecture, or at least that of Tunis. I mean no one went toTunisia before the revolution: it was a journalistic dead zone. And then came the uprising, the confused aftermath and then the October elections, and each time, we would wander around the tree-lined Bourguiba avenue, with its never-ending outdoor cafés and beautiful peeling old buildings and think, wow, now THIS is a capital city.
Up until this point, if what you've seen of Arab capitals is the slow motion urban train wreck of Cairo, the bland concrete and glass of the Gulf and the soul destroying beige ugliness of Baghdad, Tunis was amazing.
Until I saw Algiers. The white city on the sea has just block after block of achingly beautifully filigreed white buildings with delicate blue balconies arrayed around a perfect semicircular bay, climbing up a steep mountain like an amphitheater.
There are drawbacks. Everything built from the 1950s on is hideous and unlike Alexandria's lovely bay, the Algiers port is, well, smack dab in the center of the bay, so once you got close to the water, you are dealing with warehouses, train tracks, highways and chainlink fences guarding customs buildings.
But climb the hill and and there you were in winding streets connected by steep staircases, working your way through old neighborhoods. So Algiers was a rare enough site to visit, but this time around, the government wanted to invite the world for their elections, their "spring."
It was time to throw a party, show off the city and tell the world how Spring-like Algeria was feeling. It was the regularly scheduled parliamentary elections, elections the country has been holding regularly every five years like a train schedule, and with about as much literary merit. But since everyone was looking around the region saying, "where's your spring Algeria?," the aging regime of old revolutionaries felt they had to put on a show. So the observers were invited in, the journalists suddenly got visas, and a fairly closed place was suddenly thrown open — much to the joy of those who love old colonial cities.
As it turns out, asking Algeria experts why there was no "Arab Spring" in Algeria, could possibly be the equivalent of asking the inane post 9/11 query of "why do they hate us?" They do get tired of that. One answer is that Algeria had its spring in 1988 when angry riots over a failed system broke out around the country necessitating a massive army crackdown that killed 500 people — roughly proportional to the numbers that died in Tunisia and Egypt's 2011 revolutions.
The result was a multiparty system ahead of its time, some fairly free elections and then… well, the military coup, the Islamist rebellion and 10 lost years of grinding bloodshed as the military that built that country made sure it didn't have to let it go.
The other answer, is how many Middle East nations just dripping in hydrocarbon wealth had a "spring?" Those who could bought their way out, unless they had mismanaged the whole situation so badly like Gadhafi that it went violent from the get go — and then only succeeded thanks to NATO's air force.
Despite being a country of 35 million people, with a highly educated middle class, and a rich history, Algeria can be understood by some of the same logic as a Gulf monarchy. Politics in many ways has died off in Algeria, what it is really going on, is a competition for who gets what handout. And thanks to the ever rising price of oil, there's huge pie to compete for.
For a rich country, many Algerians feel poor, or at least feel they should be doing better than they are, and there's that sneaking suspicion that everyone above them on the economic ladder is just doing a better job of siphoning off that rich load of state money than they are. People despise politicians because they are paid well, why would I vote someone into power just so they can make a bunch of money? Where's my share?
Tunisia and Egypt and elsewhere worked because people, for a brief shining moment, threw aside all their differences and got together in the street for a single goal, usually the ousting of one very obviously awful leader. In Algeria that could never come together, who would unite people? Why would you give one person your allegiance when he was probably making some kind of buck out of it? Or was in the pay of security?
So elections were this bizarre piece of theater where an incredibly cynical government of political players par excellence urged everyone to vote for… Algeria's Spring. "Our spring is Algeria," said the ubiquitous get-out-the-vote poster. Posters for candidates were restricted to a limited set of oft-vandalized billboards, but the posters advertising the vote itself, were everywhere.
If you don't vote, there will be chaos. And if there is chaos, there will be foreign intervention. It will be French colonialism all over again. We'll be Iraq, or Libya, or even worse, if you don't vote, went the campaign speeches of the government politicians.
Meanwhile pretty much anyone you talked to would say, why vote? the parliament is powerless, the politicians are corrupt, the elections are rigged.
But the thing is, I thought this time the government was serious, this time they would really try to let the opposition movements have their say and breathe, just to let off a bit of steam in a closed political society subsidized by natural gas.
Some of the opposition seemed to feel that way as well, though their confidence smacked of that Egyptian opposition kind, when their local intelligence service minder has promised them 50 seats in the next parliament if they just don't boycott.
As it was, Algeria continued to buck the trend, whether it was in meaningful elections, or Islamist parties winning, or doing something that just didn't reek of the same old stultifying status quo, but the former single ruling party of aged war heroes nearly doubled its seats. It was particularly painful coming just two days after the cancer-ridden president, a foreign minister in the 1965 government of Colonel Boumendiene, told the country that the generation of the independence struggle was finished and it was time for a new generation.
Apparently that new generation still has to belong to the National Liberation Front, because they're the ones still running the show.
But the thing is, if you have a system where no one votes, it's just going to be those rickety old pensioners who do remember the independence struggle and who do think that the FLN is the only solution who cast their votes. The 40+ other political parties didn't really have popular support. Many of them consisted of one well known ex-government official, a few friends, and a fax machine to send out press releases.
The three-week campaign was largely a series of poorly attended rallies around the country where the new parties tried to articulate their program but mostly spent their time urging people to vote. The one exception I saw was Amar Ghoul, the head of the Algiers list for the "Green Alliance" of Islamist parties.
I saw him campaign in the fairly gritty neighborhood of Harache in Algiers and he told young people that if they wanted jobs, they had to organize, and he walked through the streets and greeted cafe owners and listened to people with their housing woes, including a dramatic example where an entire floor had disintegrated in one low slung apartment building, leaving the families there living in debris. He listened with concern, hugged an old woman, shook hands in the streets — it was like a real campaign, it inspired hope for change. As I was leaving, I saw a man at the nearby covered market, with steel grey hair and piercing blue eyes watching the politician move through his town with his entourage and I asked him if maybe, just maybe, this was something worthwhile?
"It's nothing he snorted, just air," he said with disgust, before turning away and walking off.


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Suzanne Louise Topalian, M.D.
Associate Director, Bloomberg~Kimmel Institute for Cancer Immunotherapy
Professor of Surgery
Languages: English, French
Expertise: General Surgery, Melanoma, Skin Cancer
Research Interests: Mechanism-of-action of immune checkpoint pathways; clinical development of drugs and drug combinations modulating immune checkpoints in cancer therapy; identification of predictive biomarkers for the activity of immune checkpoint blocking drugs. ...read more
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Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
401 N. Broadway David H. Koch Cancer Research Building, Suite 508 Baltimore, MD 21231
Phone: 410-502-8218 | Fax: 410-502-1958
Dr. Topalian received her undergraduate degree from Wellesley College and went on to receive her medical degree from Tufts University School of Medicine in 1979. She then went on to complete her residency in general surgery at the Thomas Jefferson University Hospital in Philadelphia, after which she held two fellowships — the first in Pediatric Surgery Research at the Children's Hospital of Philadelphia (1982-1983), and the second in Surgical Oncology at the National Cancer Institute, NIH in Bethesda, Maryland (1985-1989). In 2006, after a 21-year tenure in the Surgery Branch of the National Cancer Institute, Dr. Topalian joined the Johns Hopkins faculty to lead the Melanoma Program in the Sidney Kimmel Comprehensive Cancer Center.
In the laboratory and in the clinic, Dr. Topalian serves as a physician-scientist whose research interests focus on cancer immunology and immunotherapy. She has published over 100 original research articles and reviews in this field and is internationally recognized for this work. Dr. Topalian's basic studies of human anti-tumor immune responses have provided a foundation for the translational development of immunotherapies for melanoma and other cancers, including cancer vaccines, adoptive T cell transfer, and immune-modulating monoclonal antibodies. Her early work established that cytolytic "killer" T lymphocytes in melanoma patients could specifically recognize tumor cells from the same patient. Later studies confirmed the existence of "shared" melanoma antigens (proteins) among tumors from different patients, paving the way for the clinical development of melanoma vaccines. Seminal investigations into the role of CD4+ T "helper" cells in human anti-tumor immune responses revealed the existence of tumor-specific CD4+ T cells in patients with melanoma and other cancers, and biochemical and molecular methods were devised for identifying the recognized tumor-associated proteins.
As the Director of the Melanoma Program, Dr. Topalian's current work focuses on modulating immune checkpoints such as PD-1 in cancer therapy, and discovering biomarkers predicting clinical outcomes following treatment. She continues to work on devising optimal melanoma vaccines, based on biochemical and structural analyses, with the goal of exploring combination treatment regimens of vaccines with PD-1 blocking drugs. These pioneering efforts have opened new avenues of scientific interest and clinical investigation in cancer immunology, and have helped to establish immunotherapy as a treatment modality for cancer.
Dr. Topalian was elected to the National Academy of Medicine in 2017.
- Associate Director, Bloomberg~Kimmel Institute for Cancer Immunotherapy
- Melanoma Program Director
- Professor of Surgery
- Professor of Oncology
- MD, Tufts University School of Medicine (1979)
- Sidney Kimmel Medical College of Thomas Jefferson University / General Surgery (1985)
- National Cancer Institute- NIH / Oncology (1989)
Research & Publications
Research Summary
Dr. Topalian's research prior to joining Hopkins revealed the existence of melanoma-associated proteins ("antigens") specifically recognized by human CD8+ killer and CD4+ helper T cells, paving the way for the clinical development of melanoma vaccines. Disappointing results with cancer vaccines in the clinic led to the realization that melanoma and many other human cancers can avoid immune detection and destruction by displaying molecular shields and secreting immune-suppressive factors. Dr. Topalian has led the clinical development of immune-modulating monoclonal antibodies to break through this shield and effectively treat patients with melanoma and other solid tumors. In collaboration with an interdisciplinary research group at Hopkins, Medarex/Bristol Myers-Squibb, and other medical institutions, it was found that patients with treatment-refractory advanced metastatic cancers could respond to blockade of the immune cell inhibitory receptor programmed death-1 (PD-1) or its partner molecule PD-L1 on tumor cells. Research led by Dr. Topalian has characterized the pharmacodynamics of anti-PD-1 and anti-PD-L1 drugs and has explored tumor molecular markers predictive of clinical response. Since animal models suggest that blockade of PD-1 and PD-L1 synergizes with cancer vaccines, Dr. Topalian has continued to search for optimal tumor target antigens, investigating mutated peptides, phosphorylated peptides, and structural interactions between T cell receptors and these antigens in collaboration with Dr. Roy Mariuzza at the University of Maryland. Combination treatment regimens of anti-PD-1/PD-L1 with other immune-modulating antibodies, kinase inhibitors, and epigenetic therapy are under development.
Clinical Trial KeywordsDirector, Melanoma Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Selected PublicationsView all on Pubmed
Brahmer JR, Drake CG, Wollner I, Powderly J, Picus J, Sharfman W, Stankevich E, Pons A, Salay TM, McMiller TL, Gilson MM, Wang C, Selby M, Taube JM, Anders R, Chen L, Korman AJ, Pardoll DM, Lowy I, and Topalian SL. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics and immunologic correlates. J Clin Oncol 2010; 28:3167-75.
Taube JM*, Anders RA, Young GD, Xu H, Sharma R, McMiller TL, Chen S, Klein AP, Pardoll DM, Topalian SL*, Chen L*. Co-localization of inflammatory response with B7-H1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Science Transl Med 2012; 4:127ra37. *co-corresponding author
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, Pardoll DM, Chen L, Sharfman WH, Anders RA, Taube JM, McMiller TL, Xu H, Korman AJ, Jure-Kunkel M, Agrawal S, McDonald D, Kollia GD, Gupta A, Wigginton JM, Sznol M. Safety, activity and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012; 366:2443-54.
Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, Brahmer JR, Lawrence DP, Atkins MB, Powderly JD, Leming PD, Lipson EJ, Puzanov I, Smith DC, Taube JM, Wigginton JM, Kollia GD, Gupta A, Pardoll DM, Sosman JA, Hodi FS. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol 2014;32:1020-30.
Nghiem PT*, Bhatia S, Lipson EJ, Kudchadkar RR, Miller NJ, Annamalai L, Berry S, Chartash EK, Daud A, Fling S, Friedlander PA, Kluger HM, Kohrt HE, Lundgren L, Margolin K, Mitchell A, Olencki T, Pardoll DM, Reddy SA, Shantha EM, Sharfman WH, Sharon E, Shemanski LR, Shinohara MM, Sunshine JC, Taube JM, Thompson JA, Townson SM, Yearley JH, Topalian SL*, Cheever MA. PD-1 blockade with pembrolizumab in advanced Merkel-cell carcinoma. N Engl J Med 2016; DOI:10.1056/NEHMoa1603702. *co-corresponding author
Activities & Honors
- Federal Technology Transfer Award, 2003
- Member, National Academy of Medicine, 2017
- American Association for Cancer Research;
- American Association of Clinical Oncology;
- American Association of Immunologists
- Society for Melanoma Research;
- Society for the Immunotherapy of Cancer
Professional Activities
- Chief Scientific Officer, Melanoma Research Alliance
Videos & Media
Immunotherapy & Melanoma
Patient Ratings & Comments
The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
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Posted: Caamsaa/May 28, 2015 · Finfinne Tribune | Gadaa.com | Comments
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Arranging regular termite inspections in Cobbitty (once a year in cooler and twice a year in warmer areas) is the best way of controlling termites before they can do any damage. During early spring and late summer termite activity is usually at its highest so it makes sense that inspections during these times will be most beneficial.
Another weapon in your termite control in Cobbitty armoury is to keep the edges of the house clear of clutter. And don't forget that termites sometimes find perfect hiding places in garden beds and vegetation. So keep these as clear as possible from any clutter as well.
While home owners can inspect houses themselves if they can identify termite activity, it is important to get a trained professional to do it at least once or twice a year. This will ensure that you haven't missed anything.
If you do find any termite activity in or around your house, don't disturb them. You may cause them to spread further because chances are that you won't eradicate them completely. It is important that you call the professionals to deal safely and securely with them.
Here are a few facts people don't generally know about termites:
- Every year more damage is done to homes by termites than both fires and storms combined.
- 1 in 3 homes either have active termite activity or a history of it.
- No household- or home-owner's insurance covers for termite damage.
- Having a steel framed structured building doesn't mean it is safe from termite attack.
Many people think that termites only attack timber. However, a CSIRO study showed that steel framed and brick structures are as vulnerable to termite attacks as their wooden counterparts. This is because the termites will attack other cellulose based materials used in these constructions such as window frames, timber doors and skirting boards.
Almost like human villages, termites live in colonies. And just like every person in a village has a different task, termites also have specific functions. Another comparison is that just like the population count for a village varies, so does the size of a termite colony. Their colonies vary from a few hundred to hundreds of thousands or even millions. Some species build mounds, some nest underground and some live in small colonies while other colonies will nest in the wood of trees.
As they forage for food below the soil, they sometimes by chance will gain access to your home from the sub floor area, the slab's edge or even timber structures that are attached to the house. This is why it is important that you don't only have a termite inspection done when you move into a new house. Every property owner should have an inspection done at least every six to twelve months to make sure their property is termite free.
With termites being the most destructive of all wood attacking pests, they attack timber while feeding mainly on cellulose. Cellulose is found in all timber. The termites constantly feeding on the timber will soon destroy it. When looking to eradicate termites from your property, it is important that the nest is found and destroyed. If the nest is not destroyed you will have further termite damage and treatment will have to be repeated.
Forensic Pest Management Services has been licensed by the the state governing body of Pest Control within New South Wales. Our commitment to our customers ensures you that we provide the best possible preventative termite control in Cobbitty that measures as well as providing effective termite treatment in Cobbitty methods. During the whole process we will cause minimal disruption to your household and adhere to all regulations regarding your health, safety and protecting the environment.
Control methods for termites can essentially be divided into two groups, prevention and treatment. Preventative measures are applied during the construction of new buildings and treatment is applied to pre-existing buildings.
There are different options that can be used in the control of termites, such as baiting and application of termiticides. The only ways of getting rid of termites completely are either through the use of chemicals or baiting. With baiting the chemical is applied in a designated, well-controlled manner. People sometimes ask about the installation of non-chemical physical barriers as a part of termite control. Unfortunately, this is only possible during construction of the building and can't be done in existing structures.
Pre – Construction Termite Control
Pre-Penetration termiteProtection
One method of pre-penetration termite protection is through pipe penetration collars. These collars are available in various sizes and act as a physical barrier to stop attacking termites from entering a building through the pipes.
TERM-seal Ura-Fen Shield is a sheet termite barrier installed in buildings during the construction process. It doesn't only guard against termites but is also good against moisture and damp. It is made of a top and bottom untreated polyolefin cover sheet with an active matrix sheet of open cell polyurethane foam that contains 2gm/kg Bifenthrin as the active ingredient. Ura-Fen Shield can only be installed as a complete termite and moisture barrier while a building is in the construction phase, as it is installed under concrete slabs, across cavities as a building perimeter barrier, joints and penetrations or as an ant capping. This barrier is UV stable and designed to last.
Termseal Multi-Purpose Active is a termite and water proofing combination. It is applied as a two-in-one application. It is applied to back filled walls, slab edges, internal walls, cavities and joints.
Many owners of new buildings prefer to 'build in' termite treatment while the building is being erected. Therefore many new buildings are being protected against termite infestations by creating a termiticide-treated layer of soil surrounding and under the building. This forms a barrier that is used together with the physical methods to protect against termites. The termiticide is applied to the soil under the slab and around the footings, pipes, conduits and other structures of the building during the construction stage to form a vertical barrier. The building is also protected horizontally as further loosened soil around the perimeter of the house, including around all pipes and service facilities, is treated during and after construction.
A termite reticulation system is a perimeter- and under slab irrigation system. It allows for easy termiticide application. The system is ideally suited for both pre- and post-construction termite control. A specially designed pipe system is installed around the external perimeter of a new construction. It is often also installed under the slab of the construction. The pipe is then pumped with a termiticide and through controlled weep holes, the chemical drips out and impregnates the soil to form a protection barrier against termites. Over a number of years, the system can become less effective, so it is recommended that it be replenished/recharged through the fill-up points of the pipe system every 2 to 3 years.
Post – Construction Termite Control
Because of ineffective termite treatments used on termite colonies during previous treatments, it is possible that termites may be present in a house with no connection to the exterior. This usually happens because of a previous treatment conducted with older termite control products that are repellent, thus trapping them inside with no choice but to feed solely on the house timbers. This was really a case of making a bad situation worse.
Also, leaking plumbing inside the house can create conditions where the termites do not need to return to the soil as their moisture source. What makes it worse is that under these conditions, no liquid treatment will be effective. The moisture will dilute the liquid treatment, rendering it ineffective. In these cases we use Termidor termite dust.
Termidor dust is either applied directly on the termites or gets applied to any places there are evidence of termite activity such as in the interior or exterior of the building. It is also used in yards, trees or fences. Once the Termidor dust is applied, the affected termites become carriers of the dust. They carry the dust particles on their bodies, spreading the dust to other termites within the entire colony.
People need to understand that eradication of one termite colony with Termidor Dust doesn't guarantee protection from a future attack by other colonies in the area. Therefore, to ensure future termite control, the application of a chemical barrier or termite baiting and monitoring system is recommended.
The Australian Standard for termite control states that an initial remedial treatment such as dusting be conducted before applying the longer lasting chemical treatment, thus creating a chemically treated zone.
A termiticide such as Termidor is applied as a continuous chemical soil zone around the external walls, footings and sub floor areas of a building. The termiticide is applied either by creating a trench or by injecting it into the ground. Because termites often use footpaths and patios to gain entry into a building, the termiticide can also be injected through these.
Termidor is non-repellent to termites. This means that they cannot see or smell the product and therefore will not avoid the treated area. As a result, the termites continue to randomly forage through the soil until they encounter Termidor. Once this happens and they get a lethal dose, the whole termite colony will soon be eradicated.
The way Termidor works is by moving only a small distance outward from the site of application before binding tightly to organic material in the soil. This means that Termidor concentration decreases with increasing distance from the site. The termites will come into contact with the lowest concentration of Termidor first. Some of them will survive and end up transferring the termiticide to others in the colony through normal feeding and grooming. This unique Transfer EffectTM is devastating to other termites not directly exposed to the Termidor treated zone. It could wipe out the entire colony. If termites continue to tunnel into the treated soil where the Termidor concentration is higher, they will die more quickly. This makes Termidor very effective as it is two termite treatments in one.
Strategically placed bait stations are used to attract termites with a food source that is attractive to them, such as dry wood or paper refuse. These bait stations are installed every 2 to 3 metres around the exterior of the building and once the termites are attracted to and feeding from the bait stations, a termiticide is added. Just as the case is with the chemical barriers, the termiticide is then quickly spread through the colony. As feeding on the bait continues and more termites are affected, the worker termites will die. With the worker termites dead, the whole colony will soon be destroyed.
The bait stations should be regularly assessed by a professional. Once it is determined that a colony has been eliminated, the bait should be replaced with dry wood. By doing this, the bait stations will act as a monitoring device for future termite activity. This will help in finding future invasions before they can do damage to the building.
A termite reticulation system is a perimeter- and under slab irrigation system that infuses termiticide into the area where it is located. It allows for easy termiticide application. The system is ideally suited for both pre- and post-construction termite control. A specially designed pipe system is installed around the external perimeter of a new construction. It is often also installed under the slab of the construction. The pipe is then pumped with a termiticide and through controlled weep holes, the chemical drips out and impregnates the soil to form a protection barrier against termites. Over a number of years, the system can become less effective, so it is recommended that it be replenished/recharged through the fill up points of the pipe system every 2 to 3 years.
Call Forensic Pest Management Services today to book an appointment. We will assist you with all termite inspections in Cobbitty.


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PARIS - It was not your run-of-the-mill Paris sports club. It was Chanel haute couture.
In Karl Lagerfeld's dazzling "Cambon Club" show he boldly mixed the couture designs associated with Coco Chanel's fashion empire at 31 rue Cambon with a youthful sporty kick.
Princess pearl chiffon, satin silk, fastidious embroideries and sculpted corsets were paired with sneakers, sporty white cropped boleros, fanny packs and silver elbow and knee pads.
Models skipped, twirled and even ran down the steps in their bouncing footware onto a glacial, crystalline stage that featured a large orchestra.
If the spring-summer 2014 show felt like it had less vibrancy than recent colorful Chanel displays, it was due to the more muted pearly and silver palette — with touches of lilac blue and rose pink.
Still, the details of the clothes certainly packed a punch.
Tight corsets sculpted the midriff, which was made graphic and extreme by the overhanging space from the wide truncated boleros.
Hair was worn up and fanned out as if blown around by the elements. And there were a series of spiky, sea urchin-like looks in iridescent green and blue.
Lagerfeld said he wanted the sneakers to "bring couture back to reality."
"They models run downstairs... like modern Cinderella," Lagerfeld said. "We didn't need the stiletto in glass."
Thomas Adamson can be followed at https://twitter.com/ThomasAdamsonAP


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Software Police and Software Thieves/
Know Your Rights and Stay Free
The clash between software companies wanting to protect their intellectual property (IP) revenue streams and software users continues in full force and has begun to pull in a wider cast of characters. The "software police," the most well-known of which is the Business Software Alliance (BSA), have moved from large enterprise targets to schools and small businesses. This year lawyers who think that they are below the radar may get a rude awakening.
"But wait," you say. "They aren't targeting me. Our firm pays good money for software and more for upgrades." Maybe so, but how methodical are you about matching the number of licenses to the number of PCs? Do you keep accurate inventories of which PCs have which licenses? New computers come into your office, old ones go out—are your records up to date? You may have no intention of using software illegally. But how would you look if the BSA audited your firm?
This article reviews the requirements of software licenses, consequences of violating them, and steps you can take to protect yourself and your firm.
License Requirements
Unlike most other products you buy, software programs don't allow you to do whatever you want with them. Your use is governed by the license of IP rights that accompanies your purchase. A license can slice and dice the IP rights in a nearly endless number of ways: number of copies allowed, where the software may be installed, whether it may be transferred, who can use it and for what, and more.
In general, if you copy or make use of a software program without a license to copy or use it in that particular way, you infringe the rights of the IP owner. The license in essence allows you to avoid a claim of infringement. The presumption is that you cannot use the program a specific way unless the software license clearly authorizes that use.
As a practical matter, however, the legal nuances are implemented when the IP owners set out the program's limited set of rights and specify restrictions and prohibitions. We generally look at licenses to see what we can do rather than what we can't do. That is, of course, if we look at them at all.
When the Heck Did I Agree to That?
Most of us are familiar with software license agreements only as lines of small type that precede the "I accept" button that must be clicked in order for the software installation to begin. The thought may cross your mind, "They'll never be able to enforce these terms. I didn't sign anything." Think again.
The current state of the law is that such "click through" contracts are valid and enforceable, assuming the user can reasonably access the terms of the contract and indicate agreement. However, specific licensing provisions, especially those relating to future arbitration and choice of venue requirements, might be found unconscionable or otherwise not enforceable. This area of law continues to evolve; at this point, it's unlikely a court would invalidate click-through contracts generally.
Are You a Pirate?
If you, the user, do not have a license, act outside the scope of your license, or use the software in a manner prohibited by the license, you are an infringer or "pirate." Intent does not matter. Some of the most common violations include the following:
- Having more people use a program than you have licenses for
- Installing a program with a single license on multiple computers
- Making more copies of a program than allowed (licenses typically allow an operating copy and one backup copy)
- Using upgrade software without proof of a legitimate underlying license
- Improperly using academic and OEM (original equipment manufacturer) versions of programs
- Downloading or purchasing and using "free," highly discounted, or other dubiously created copies unaccompanied by legitimate authentication materials
- "Borrowing" a program from a friend or using office software at home
Note that it is easy to inadvertently violate license provisions. Lack of adequate record keeping often leads to problems. You can easily be a pirate without intending to plunder.
Getting Caught
A phone call or e-mail sent by a disgruntled (or law-abiding) employee or former employee can put you under the BSA enforcement microscope. The whistle-blower likely knows what the violations are and where to find them, and BSA conducts a thorough interview and a licensing investigation before you're aware of a thing. Then you receive a letter asking you to demonstrate that you are in compliance with your licenses.
Let's assume you were not purposely disregarding the software license terms. In response to the letter, you submit whatever proof of licenses you have, likely revealing one or more shortcomings. As a practical matter, the next step usually is an offer to settle—unfortunately, however, the proposed settlement will not be a slap on the wrist. First you'll be required either to delete infringing copies or purchase the lacking licenses. Second (and more painful), you'll be asked to cover infringement damages by paying a significant settlement amount. You may have some room to negotiate this amount down, but don't expect much. During the past five years, BSA has collected more than $50 million in settlement payments in North America.
Suppose an employee did the pirating and you knew nothing about it. The law on vicarious liability for infringement leaves little doubt: You are liable for the actions of your employees.
It's important to emphasize that running out and buying the missing licenses as soon as you get the letter does not absolve you of the problem. It simply gets you to where you need to be from that day forward. You still are on the hook for the infringement that occurred before you came into compliance. Audit letters typically state that the software inventory must be accurate as of the date you receive the letter.
What about deleting the unlicensed copies after you get the letter or taking other steps to hide what you did? Seriously . . . is there a question? You learned the answer to this one in law school, if not preschool. Someone turned you in for doing what you were doing—the auditing party already has a good picture of what it was.
It's worth noting that some lawyers recommend not responding to an audit letter, especially if the response demonstrates liability. The software police, however, have no problem pursuing litigation. In fact, at least one organization's website has a map of the United States on which a click will show you a list of each state's infringement actions.
Can You Afford It?
In addition to the cost of buying additional licenses and a significant fine, what else have you got to lose? How about your reputation? Highly publicized, visible enforcement actions help keep everyone in compliance. Imagine the impact on your current and potential clients when your firm's name appears in the local paper along with the words "software piracy."
In addition to paying out of your pocket and in the press, you stand to lose a lot of valuable staff time complying with an audit by the BSA. Any audit takes the focus off the client work you and your employees want to be doing, but a piracy situation may trigger alarm or cause morale to suffer. Everyone's perception of what it's like to work at your firm may be tarnished.
In the end, you spend and expend much more time and energy than you would have spent tracking the original software purchases. And that's not even mentioning the additional stress. Serious violations may bring about more serious consequences. Copyright infringement carries both civil and criminal penalties in the United States—an infringer may be liable for damages and for any profits that can be attributed to the unlicensed use.
In case we still don't have your full attention: You also may be liable for statutory damages up to $150,000 for each work infringed and subject to criminal penalties of fines up to $250,000 and imprisonment for up to five years.
Can You Get Away with It?
Ironically, the idea that you're saving money by going outside software companies' licensing programs may well be urban myth. Volume discounts often are available for as few as five copies of a program. Support, upgrades, and other benefits now are standard parts of some licensing programs. Microsoft, for example, has a rebate program for Office 2003, plus a new home-user program that allows employers to give employees copies of certain programs to use at home (which could also double as a new employee benefit). Microsoft's licensing program also allows you to use earlier versions of programs when you license current versions, which makes throwing away your money on cut-rate, dubious-sourced older versions really foolish. Some Microsoft licensing programs even help you keep track of and manage licenses electronically.
Obtaining software from "bargain" sources on the Internet often gets you more than you dreamed of—new viruses and security holes in your systems, no technical help, inability to get updates and patches, and continued reliance on obsolete software. What a deal—in today's questionably secure electronic environment, you're begging to become a hacker haven.
Finally, be aware of the risk you take by endorsing an atmosphere in your firm where bending the rules, ignoring requirements, cooking the books, and committing outright theft are tolerated. Remember the doctrine of vicarious liability for infringement; software piracy could turn out to be the least of your problems.
Taking Charge of Compliance
Picture yourself opening a demand letter from the BSA. What feeling do you get in the pit of your stomach? Think about digging through files and boxes and storerooms for those old software licenses. If these mental pictures are ugly, use them as motivators to take the first step in straightening out your software license mess.
You are not alone. It is hard enough simply to keep on top of licensing for one person using one computer. Receipts, proofs-of-purchase, original boxes, hundreds of manuals, unlabeled disks—the stuff's like the Hulk. The problem expands even further when you factor in new computers, program upgrades, laptops and PDAs, and the occasional (but usually unfinished) clean-up-the-file-room binge.
But would we paint such a dismal picture without a sunny solution on the horizon? For a small investment of time and money, you can have a network inventory program do part of your work, like scanning all computers and listing all the installed software programs. We like Newt Professional from Komodo Digital, which offers a version for up to ten PCs as a free download (www.komododigital.com). Installing and using the file is not difficult, but you may run into trouble automatically accessing multiple computers if you don't have peer-to-peer networking. (Even so, you'd just need to install and run the program individually on each PC.) Similar products are available from EMCO Software (www.emco.is) and DEK Software (www.deksoftware.com). For the paranoia-free, BSA also offers free software audit tools and other information (www.bsa.org).
Go Forth and Sin No More
The following information will help you take charge of your licensing position and maximize your level of compliance. Because daily emergencies are likely to intrude on this project, consider bringing in an outside consultant or support person to get the job done. Using this seven-step process will bring you in line with the law, provide numerous collateral benefits, and protect you in the event of a future software audit.
1. Inventory software and hardware. Everything starts with getting a handle on what you have. Some firms couldn't tell you how many computers they have, let alone all the software programs they use. Include hardware in the inventory because some licenses require that programs be operated only on certain computers or even specific processors. Your final lists should include the following: all installed programs; the computers each program is installed on; users for each program; unused and uninstalled software programs; and a brief description of what each program does, ideally accompanied by the name of the employee who knows most about the program.
2. Locate license agreements, receipts, and other documentation you have for each program. Unfortunately, you can work only with what you have. Scour your office and storage spaces for whatever might be applicable. Using a liberal supply of filing boxes, hanging files, and file folders, organize or reorganize these materials.
3. Match programs and licenses. This task is both tedious and frustrating, but it's got to be done. Using a spreadsheet (make sure at least the copy you use is licensed!) to enter and track this information helps—data can be formatted in charts and numbers calculated automatically.
4. Read the licenses. Focus on what the license specifically grants; specific restrictions, prohibitions, and permissions; and users'rights to transfer or assign licenses. Note all limitations or restrictions and be particularly alert for rights you may have, such as the right to install on a laptop or home computer. It makes sense to add a summary of the license terms to your inventory spreadsheet for quick reference.
5. Create an action plan. The inventory process has a hidden bonus: identifying unnecessary costs and other inefficiencies. Are you paying annual maintenance fees for programs no one uses? Was that expensive new program ever used? Do you have extra licenses for certain programs? Have you missed opportunities for volume discounts? Focus closely on programs for which you are underlicensed. In some cases you can eliminate the deficiency by restricting the number of users or, in the case of obsolete or rarely used programs, deleting them. At the end of this process, you should have the major issues identified and a clear list of next steps.
6. Do your best. As you might have guessed by now, the odds are quite low that you'll dot every "i" of software compliance. You will have to make some judgment calls based on your level of comfort with your documentation, changing or restricting the use of programs or even deleting a few. You might decide to purchase additional licenses for others. Your general goal is to reach a point where you can do business comfortably.
7. Implement a system to stay in control. Staying in compliance is one part working with a good system and one part picking the right people for the job. Proficient techs may be poor record keepers. Your bookkeeper might be the right person for this responsibility. The system, however designed, should provide a simple way to stay accurate and up to date on inventory. Consider adding a discussion of acceptable software use to your orientation materials for new and existing employees and a policy to your employee/office procedures manual.
The Parrot Did It: Help for Pirates
The first three websites below, although somewhat biased, have good information on piracy and infringement issues, license programs, and compliance procedures and tools. The final article describes the BSA and BSA audits.
Microsoft: www.microsoft.com/licensing, www.microsoft.com/piracy
Business Software Alliance: www.bsa.org
What Are the Repercussions of a BSA Audit? www.asia.cnet.com/itmanager/trends/0,39006409,39039672,00.htm
Lisa Radcliffe, Software Licensing: Protecting Your Organization from Lawsuits,The H.E.L.P. Organization, www.uwnyc.org/technews/pf_v2_n4_a3.html


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The Pheasant Cap Master and the End of History: Linking Religion to Philosophy in Early China
Paperback, 264 Pages
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Following a catastrophic defeat at Changping in 260 BCE, and the reported immolation of close to half a million Zhao soldiers by Qin, a mysterious figure appeared on the stage of history. He was called Heguanzi, the 'Pheasant Cap' master and appeared incognito. Seemingly a political refugee, this Daoist Demosthenes in outspoken jeremiads warned against a looming danger of total collapse and Zhao's imminent annexation by the ruthless kingdom of Qin. Pheasant Cap's writings, long neglected and misunderstood, combine a potent mix of religion, metaphysics, philosophy, politics and strategy to unroll a vibrant picture of life and death in perhaps the most climactic period of Chinese history. Against the totalitarian system of Qin, he offers an alternative vision of meritocracy and inclusiveness to unite a fractured world. Marnix Wells offers readers the first full translation and analysis in any language.
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Product Details
- 9781931483261
- Copyright
- Marnix Wells (Standard Copyright License)
- Edition
- First
- Publisher
- Three Pines Press
- Published
- April 3, 2015
- Language
- English
- Pages
- 264
- Binding
- Perfect-bound Paperback
- Interior Ink
- Black & white
- Weight
- 1 lbs.
- Dimensions (inches)
- 6 wide x 9 tall
- Product ID
- 22114451
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text:
2014 Range Rover Sport: The All New Discovery Platform For Sports SUV Enthusiasts
This year, the Range Rover is not at all the same as it used to be earlier. The all steel structure of 2014 Range Rover Sport has underpinned even the last years Land Rover model and fails borderline from being sporty. However, the new owners of Land Rover i.e. Tata Motors have deployed a new generation aluminum structure which is light in weight and was also seen first time in the Range Rover launched last year. The weight reduction for a 2014 Range Rover sport is somewhere around 800 pounds which actually makes some difference.
However, the weight reduction might seem interesting to some if you give importance to the expanded dimensions of this version. Newly launched 2014 Range River Sport is 2.4 inch longer and 2.2 inch wider in comparison to its predecessors. The additional seven inches on wheel base make this SUV more subtle and balanced while also getting away from its predecessors' bling styling. The newly introduced seven seat option, which is usually not a part of a full Range Rover is good but perches are small. However, no comprise is made on seating space and enough attention is paid to the comfort of driver as well as passengers.
Quality improvements in the well equipped, well designed and reconstructed inside cabin are quite apparent with extra wheel base offering more space. Reorganized seats have made seat comfort a priority with a bit of compromised luggage space, but we are not complaining. Materials used for building interiors are certainly of high quality and feels lovely to touch, must say the interiors are well thought while designing. However, rear seats are only generously comfortable, but overall the Range Rover sport offers loads of useful storage options and rather grand front seat comfort.
All electronic dashboard seems a little dumpy and disappointing in comparison to the remaining interior and the touchscreen controls of the infotainment panel are also a bit laid down as compared to the touchscreen panels available on its competitors. While on road, the 2014 Range Rover Sport ensures comfortable ride, graduated roll control, subtle approach to road bumps and well weighed steering that offer accurate performance. Some test drivers might find wading depth indicator a gimmick but is completely optional. Riding on tough rocks and want to protect tires? Here comes the all around cameras to show the exact position of the wheels in relation to the road, and trust it's brilliant.
For a tough journey among mountains and mud, 2014 Range Rover sport is the SUV to watch out for as the comfort it and driving dynamics it offer are undoubtedly not available in any other crossover coming at its price.
The next gen Range Rover starts at a price of $20,000 and also has extra two seats on offer, which is not as bad as it seem too many. If you are looking for sports SUV and belong to families hauling from rich parents then surely 2014 Range Rover Sport is your safest bet for a futuristic crossover.


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text:
Don't think the Patriots are easily bullied. Nor are they stupid like the Jets admin and coaching.
The Patriots have a plan. It's like a marketing plan in business that the better companies have. They have objectives, strategies and a tactical plan fom a personnel perspective. And it's long term, not one year. The Jets change with the wind it appears.


text:
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Daler-Rowney System 3 is a versatile water-based acrylic offering lightfastness, permanence, insolubility, and covering power in an economical, medium-bodied paint. System 3 is fast-drying and has a greater pigment load than other paint in its class.
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text:
spoked II
I am woefully behind on posting FOs! Sometimes I start posts and grow unsure of just how to write them, so I end up composing multiple drafts and I'm rarely satisfied with any. So forgive any inelegant phrasing; I'm just going to barrel ahead.
This second Spoked quilt was the one I'd been intending all along when I made the first one. My friends Emily and Jim were having a baby girl, and even though Emily is not particularly girly, a deep berry color was just what I envisioned. I bought a bundle of fat quarters that would all coordinate nicely, and I just needed a fun, bold design to go with what would surely be a fun, bold little baby. The Dresden spoke idea seemed fun, and so I made that one in all aquas. I then felt comfortable enough to tackle it with the "real" fabrics.
But wow, let me tell you, the second one did not come together as easily as the first! My seams looked impeccable but there must have been something off because the dang circle wouldn't lay flat. As a perfectionist knitter, my instinct is always to take it all out and do it again. But that was not going to happen with this all-sewn-up piece. I learned to allow myself to fudge it, and I managed to wrestle it flat by sheer force (and by sewing a little more of some spokes into the seams). And I think it looks great!
The backing fabric is from a sheet I bought at Ikea for this quilt. I made a circle label for the middle of the back with an embroidered rose; I knew Rosie was high on the baby name list so I figured this would work even if they chose a different name in the moment! The binding is pieced using a few of the fabrics used in the spokes. I quilted it using concentric circles that expand by a half inch with each round, and within the spokes I outlined every other spoke. It's really a rather simple little quilt, all told.
I gave the quilt to Emily while visiting before the little one arrived, but I was lucky to go back and be able to meet Rosie just 9 days after she was born. I think she was impressed.


text:
Are Silicon Valley Angel Investors Colluding Over Deals?
from the meritocracy? dept
Mike Arrington, over at TechCrunch, has a troubling story about an apparent meeting between some of the top angel investors in Silicon Valley, allegedly to collude on deals. Arrington was alerted to the meeting -- bizarrely held at a restaurant where anyone could see them -- and while he knows these guys well, they were clearly unhappy to see him and wouldn't talk to him at all. After he spoke to some investors later, he got the scoop on what was happening:
This group of investors, which together account for nearly 100% of early stage startup deals in Silicon Valley, have been meeting regularly to compare notes. Early on it was mostly to complain about a variety of things. But the conversation has evolved to the point where these super angels are actually colluding (and I don't use that word lightly) to solve a number of problems, say multiple sources who are part of the group and were at the dinner. According to these souces, the ongoing agenda includes:As Arrington notes, this seems like a classic case of collusion and price-fixing. He doesn't name names, but if you're talking about the 15 angels who represent most of the early stage startup deals, it's not difficult to put together that list if you spend any time in startup circles. Arrington notes that some of the participants he spoke to said they were uncomfortable with the meetings, and there to "gather information, not participate," but it's still troubling. One bit of disclosure here, while I don't know who was at the meeting, if Arrington is being accurate in saying that they represent nearly all of the early stage deals, there's a very good chance that at least one of Techdirt's investors would have been involved.
- Complaints about Y Combinator's growing power, and how to counteract competitiveness in Y Combinator deals
- Complaints about rising deal valuations and they can act as a group to reduce those valuations
- How the group can act together to keep traditional venture capitalists out of deals entirely
- How the group can act together to keep out new angel investors invading the market and driving up valuations.
- More mundane things, like agreeing as a group not to accept convertible notes in deals (an entrepreneur-friendly type of deal).
- One source has also said that there is a wiki of some sort that the group has that explicitly talks about how the group should act as one to keep deal valuations down.
While there are plenty more angels in Silicon Valley than just 15, it is true that, these days, companies getting investments from some of the "top" angels is seen as the ticket needed to move up the chain to big name venture capitalists as well. So hearing that a group of these investors may be colluding to effectively fix pricing is bad news for the supposed "meritocracy" of funding in Silicon Valley, and should be seen as a pretty serious problem.
Along those lines, I should say kudos to Arrington for publishing such a story. While he doesn't name names, these investors are the key sources for many of his stories, so publishing this story is probably burning some bridges with sources. It's good to see that he wouldn't let that get in the way (not that I thought he would -- Mike's always been great in that a good story trumps all other concerns, which is highly admirable).
Filed Under: angel investing, collusion, price fixing, silicon valley, venture capital


text: funny you should ask. There is a domestic cat called a Pixiebob. It's supposed to be a feral cat an Bobcat mix. Not sure if it is or not. However I have two of them. They act like Bobcats. Our first one was 8 weeks old. We brought him home and set him down in the house. He walked over a forced my two labs of 90+lbs each off thier bed. He claimed the bed as his from that day. They never challenged the cat. He had a swagger about him. Neat breed.


text:
sxi av a GetSystemDefaultUILanguage mov eax,411 ret g2. Click next-next-..finish. Update: Batch file for lazy ones. Copy Motion Editor directory to the local disk, place this file inside and run it. Additional software: Rolly needs SonicStage in addition for Motion Editor. Fortunately for all non-Japanese speakers out there, there is an English version of that here. PS. You may also want to install 'support for East Asian languages' in Control Panel/Regional & Language Settings to prevent Japanese characters looking like boxes.
Friday, April 11, 2008
Tip of the day: Sony Rolly Motion Editor installation on English OS
20 comments:
- alijen said...
hi, i have tried it on czech windows with no luck....
when starting motion editor, error appears "Unknown error."(so typical for windows ;)) It's in japanese, but friend translated it:)... Do you know what could be the problem?
- April 13, 2008 at 12:45 AM
- alijen said...
- This comment has been removed by the author.
- April 13, 2008 at 12:46 AM
- Juan Pablo said...
just got a Japanese rolly and Ive been trying to get the motion editor to work in american Vista business....however, cant get ur file to work...hopefully I can get more help on the matter....
- June 10, 2008 at 7:28 AM
- msft.guy said...
@alijen: Did you install SonicStage? I have no idea how to troubleshoot the issue aside from trying to reinstall both Sonic Stage and Motion Editor. You could also try installing it on other computer and see if it helps..
@Juan Pablo: Could you provide me with more details on what goes wrong (or leave your contact info)? Batch file should create a log file on the desktop - can you paste it along with your observations on what happens when you run the batch file? Thanks.
- June 19, 2008 at 6:47 PM
- Terry said...
same problem as juan pablo, i installed the debugger, ur file doesnt seem to work.
Setup started
Home dir at C:\Users\Terry\Desktop\Motion Editor\.
ERROR: Debugging Tools for Windows not installed.
Please go to http://www.microsoft.com/whdc/devtools/debugging/installx86.mspx to install.
- June 22, 2008 at 12:37 PM
- msft.guy said...
The batch file could not find the file
"c:\Program Files\Debugging Tools for Windows\ntsd.exe"
Make sure the file is there, if not, install Debugging tools (32-bit) from here
to "c:\Program Files\Debugging Tools for Windows"
If you're on a 64-bit OS, you should install 32-bit Debugging Tools to
C:\Program Files (x86)\Debugging Tools for Windows\
If your Windows drive is not C:, then replace C: with your Windowss drive letter.
- June 22, 2008 at 3:21 PM
- Terry said...
problem solved i had a (x86) on my folder name.
- June 22, 2008 at 7:51 PM
- This comment has been removed by a blog administrator.
- July 22, 2008 at 3:17 AM
- FunInTheSun said...
Thanks to your EXCELLENT blog/knowledge the Rolly a Japanese friend gave me today works on my windows XP laptop.
BUT, no luck with getting the software to install on my other machines which is running under Vista. Sonic Stage installs no worries, and the batch file appears to work (changed the compatibility mode etc), but Motion Editor eventually comes up with "cannot install wrong language" about half way through the process.
Any advise you could give about getting the Rolly software to work on non-Japanese Vista would be greatly appreciated (once again thanks for the XP version).
- July 27, 2008 at 4:38 AM
- Cormac said...
Thanks for the help, I was struggling all day with the installer. I installed everything onto a portable hard-drive using an old XP laptop, and everything works fine now on my new Vista one.
- August 12, 2008 at 9:35 AM
- 123 said...
could u send the batch file to me email@example.com
- October 29, 2008 at 9:59 PM
- msft.guy said...
@123: Sorry, I've already deleted the local file :-(
You can try using the manual steps though..
- November 2, 2008 at 1:10 PM
- Hanna K. said...
Hi. I'm a girl. I had not heard about Windows Debugger until I read your post.
I've head japanese Rolly since last christmas now and I was hoping that by now an english version of motion editor would show up. No such luck that's why i looked at your info.
Problem is that I am clueless. I can open ntsd.exe and I get a black screen with commands on it. Am I supposed to just type in it? Or do something else? Please help. You're my only hope for a working Rolly this Christmas! :)
Thanks a lot
- December 3, 2008 at 10:39 AM
- Louie Ishii said...
Same problem as Hanna here..
I got the Debugger tool up and running but have no idea how to use it?
Could anyone plz write a step-by-step for dummies ;) on how to add the "motion editor" setup.exe in NTSD and how to write the commands? So I can get some moves into my Rolly ;)
Thanks in advanced!
- December 24, 2008 at 2:58 PM
- Rory said...
I have the debugger and run ntsd.exe but then what. Any more detailed info/instructions would be much appreciated. Maybe batch file might be easier for me. How can I get it now you have taken it off? And what would be the detailed instructions? Thanks so much for all your help. Really appreciate it.
- December 26, 2008 at 1:26 AM
- Rory said...
I have the debugger and run ntsd.exe but then what. Any more detailed info/instructions would be much appreciated. Maybe batch file might be easier for me. How can I get it now you have taken it off? And what would be the detailed instructions? Thanks so much for all your help. Really appreciate it.
- December 26, 2008 at 1:26 AM
- HeZoR said...
Broken link, could you upload the file again?
Also the command line parameters are incorrect, i get an error that "'sxi' is not recognized as an internal or external command, operable program or batch file."
Also, after installation, how can you use it without a proper language file? I use v1.0 that comes with mine.
- March 16, 2011 at 9:58 AM
- HeZoR said...
Loaded dbghelp extension DLL
The call to LoadLibrary(ext) failed with error 2.
Please check your debugger configuration and/or network access
*** ERROR: Symbol file could not be found. Defaulted to export symbols for ntdll.dll - ntdll!DbgBreakPoint:
7c90120e cc int 3
0:000> sxi av a GetSystemDefaultUILanguage mov eax,411 ret g
^ Extra character error in 'sxi av a GetSystemDefaultUILanguage mov eax,411 ret g'
0:000> sxi GetSystemDefaultUILanguage mov eax,411 ret g
Then a window pops up:
Symbolic Debugger for Windows 2000
Symbolic Debugger for Windows 2000 has encountered a problem and needs to close. We are sorry for the inconvenience.
And the report is:
Error signature
EventType: BEX P1:ntsd.exe P2:5.1.2600.0 P3: 3b7d848c
P4: dbghelp.dll P5: 5.1.2600.5512 P6: 4802a0b2 P7: 0001295d
P8: c0000409 P9: 00000000
I rest my case!
- March 16, 2011 at 10:16 AM
- Nguyễn Mạnh Tạo said...
khuyen mai viettel | nap tien viettel | cách nạp tiền viettel | khuyen mai mobifone
- December 16, 2014 at 11:14 PM
- Sarah Hall said...
I know how to prevent Japanese, Chinese, Korean characters looking like boxes. Anyway, thanks for sharing! With the proper assistance of our term paper writing service, your academic life can be much simplified!
- April 8, 2016 at 4:25 AM


text:
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text: Even though many thought Sarah Palin's inclusion on the GOP ticket was a ploy to get disaffected Clintonistas to vote for McCain, the latest poll from CBS and the New York Times shows that Obama now has a 2 point edge over McCain when it comes to white female voters — up 21 points from last week. Obama is now far ahead of McCain among women in general, with 54 percent of female voters to McCain's 38. Overall, Obama leads McCain, 48 to 43 percent. MSNBC's ratings juggernaut Rachel Maddow is positively gleeful about these new poll numbers, and last night, she invited Slate's Melinda Henneberger on her show to discuss Obama's new lead among women.It should be noted that Maddow says she has tried to get about a dozen Republican leaders on her show to discuss the election from their point of view. Every single one has declined, though many McCain campaign cronies, like Nancy Pfotenhauer and Tucker Bounds, have been making appearances on Chris Matthews' show, Hardball. It's unclear if they are shunning Maddow because she is new or because she is so aggressively left-leaning. Anyway, the shine is officially off Sarah Palin, as the Nation notes, "the governor's overall favorable rating has fallen to just 40 percent in the CBS/New York Times survey — down four points from last week. Palin's unfavorable rating is up 8 points to 30 percent. But the shift is even more dramatic among women, with whom Palin's star has fallen 11 points in one week." Poll: Obama Retakes Lead Over McCain [CBS News] White Women Shift, Giving Obama the Lead [The Nation]