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About Pique
Cancer immunotherapy is a rapidly evolving field. Despite promising results, long-lasting response rates remain around 10-20% for patients receiving single agent therapy. Multiple different translational studies have shown that the immune cell landscape in tumors is heterogeneous and is associated with differences in prognosis and outcome of treatment using immunotherapy.
Tumors can be divided into hot (T cell inflamed) or cold (T cell non-inflamed) according to the presence of immune cells with a particular emphasis on adaptive immune cells. Recent data from clinical studies has correlated the response to CPI therapies targeting PD-1 and/or PD-L1 with the presence of adaptive immune cells. A current large and unmet need to enhance the function of CPI therapy is to identify and target pathways that can enhance the recruitment of immune to the tumor microenvironment; thus making cold tumors hot. Thus, one important benefit of cellular vaccines is their ability to induce a local immune response in the tumor microenvironment. As this response will eventually undergo adaptive immune cell exhaustion, combining this approach with CPI therapy offers a rational approach to expanding the use of CPI.
Pique Therapeutics lead immunotherapy (PT 107) is a whole cell, allogeneic vaccine transfected with B7 and HLA. Solid tumors do not typically express both peptide MHC and a co-stimulatory molecule such as B7. Therefore, the tumor cells themselves are not capable of expanding T cells. Instead, tumor cells first must die and have their antigens taken up by professional antigen-presenting cells locally. By introducing a tumor cell that has HLA and B7 expressed (the PT 107 vaccine), this enables the vaccine to directly stimulate T cells, whether this is via a specific peptide/MHC tumor context or via an allograft context. In either case, T cells are induced to proliferate and these T cells can start the process of recruiting other T cells and B cells to the tumor. The process thus can result in a positive feedback loop of recruitment of T cells to the tumor site by the elaboration of chemokines by T cells after stimulation via the T cell receptor.
Management and Board of Directors
Christopher S. Meldrum President
Mr. Christopher Meldrum serves as President of Pique Therapeutics. Over his career, he has worked extensively with development-stage biotechnology companies, helping to secure initial financing for multiple start-up ventures. Prior to his work at Pique, Mr. Meldrum held the position of Director, Corporate Alliances, at Paradigm Genetics, a publicly-traded biotechnology company, where he led business development efforts for both the healthcare and agriculture businesses. Over the course of his career, he has successfully led negotiations for more than 80 fully-executed deals. Mr. Meldrum received his MBA from the Carlson School of Management at the University of Minnesota, and his B.A. in Chemistry from the University of Utah.
Jonathan S. Serody, M.D. Chief Scientific Advisor
Dr. Jonathan Serody serves as Chief Scientific Advisor for Pique Therapeutics. In addition to his work with the Company, Dr. Serody is Professor of Medicine, Microbiology, and Immunology at the University of North Carolina. He is also co-leader of the Immunology Program at the Lineberger Cancer Center, and Vice Chief of the Division of Hematology and Medical Oncology. Dr. Serody received his M.D. from the University of Virginia.
Keith Dionne, Ph.D. Director
Dr. Keith Dionne serves as a Director of Pique Therapeutics. In addition to his work with the Company, Dr. Dionne is entrepreneur-in-residence at Third Rock Ventures, and is an experienced biotechnology executive. Most recently, Dr. Dionne was CEO of Surface Logix, which was acquired in 2011 by Nano Terra, and prior to that he was CEO of Alantos Pharmaceuticals, which was acquired by Amgen for $300 million in 2007. Prior to Alantos, Dr. Dionne was Vice President at Millennium Pharmaceuticals. He also has strong expertise in the development of cell-based therapeutics, as he was the fourth scientist at Cytotherapeutics, a cell transplantation company. He has served as an Adjunct Professor in the Biomedical Department at Brown University. Dr. Dionne received both his Ph.D. in Chemical Engineering and his M.S. in the Program for Technology Policy from Massachusetts Institute of Technology.
Jay Brennan, J.D., MBA – Director
Mr. Jay Brennan serves as a Director of Pique Therapeutics, and brings a wealth of diverse management experiences to the Company. Over the past 20 years he has owned or operated a variety of distribution, manufacturing, and service businesses. In those businesses he has been involved in start-ups, new product development, high performance team development, and geographical sales expansion in addition to standard finance, sales, marketing, and operations functions. For the past two years, Mr. Brennan has been actively involved in the Piedmont Angel Network, serving on the Screening Committee and numerous due diligence teams. Mr. Brennan received his J.D. and MBA degrees from the University of Virginia, and received his B.A. from Colgate University.


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40 year old complaining of long protuberant nose and drooping nasal tip. Procedure completed via an Open Rhinoplasty approach to reduce and refine her bridgere while the nasal tip was elevated and sculpted. Cartilage grafts were used to further define and support the tip, giving a lifted, balanced and youthful look.
An actual patient of Dr. Slupchynskyj discusses her Rhinoplasty.
New York City Rhinoplasty patient discusses her Nose Job procedure, performed by Dr. Oleh Slupchynskyj.
Having problems after a previous Nose Surgery?
We can help!
Our surgical suite has achieved accreditation and certification by the AAAASF (American Association for Accreditation of Ambulatory Surgery Facilities).

subset: commoncrawl


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I've been feeling a bit frustrated of late and feel that may be attributed to being removed from my ability to make independent choices….what to eat, where to buy, from what source and without all the added ingredients. So I thought I'd pen (or rather, type) my frustrations.
For me, in real non-sea faring life, I like to think that I make educated choices about the food I buy and the products I use. I always endeavour to buy local, where possible…. though I do have a penchant for avocados…and understand that they're not so locally grown in Ireland… but I do try my best elsewhere! I also try to buy organic where I can. Not to join any 'movement', as I am often cajoled about by crewmates and some friends at home. I simply like to opt for the choice of non-chemically grown food versus that which is laden with potentially carcinogenic and environment-eroding pesticides.
As I don't eat meat anymore, I luckily don't need to worry so much about added hormones and anti-biotics in my food…as far as I know anyways!
Why Pay More?
Yes, I agree with the argument that buying organic is generally more expensive. Unfortunately, I am not currently in a position to grow my own fruit, veg and legumes, therefore I must rely on markets and supermarkets to provide me with my food.
For me, personally, I try look at the bigger picture and understand that to my pocket, yes it is indeed more expensive but on a wider scale it is ultimately less costly to nature, my health, the ecosystem and the future of successful food production.
I find it hard regularly getting the piss taken out of me, constant eye-rolling or sniggers firstly for opting not to eat meat, but secondly for trying to choose less processed and organically grown foods.
I hate the mocking voices I get when I mention 'organic' or 'vegan' in the crew mess. But I have learnt to bite my tongue and remember that I'm not alone out there, making educated buying choices where feasible.
My Reasoning for Going Organic
I am writing this piece, almost as a refute to those that say buying organic is 'bullshit', a a way for supermarkets to charge more and there's nothing wrong with highly processed food. I also write this for myself, to remind me why I hold these beliefs and values so close to my heart.
I want to look behind the veil of the aesthetically pleasing marketing campaigns, employed by the giant food conglomerates and learn more about the food industry, particularly that of the United States, as I will be based here for the next 6 months or so.
I must say that observing the attitudes of others around me, that ignorance can almost be bliss. If I didn't give a shit about the environment, about climate change, about nature, about animal rights and what chemicals are in my food, then modern life and the ubiquitous convenience food society would certainly be a lot less intimidating and much easier to live with.
But I feel that's not the right attitude to have. Not for me.
Things will never change if people don't assert their mindsets to see the negative impact our demand for convenience and general gluttony is having on the planet and our health.
My background
I was brought up in an Irish household that was food orientated. My Dad was a professional chef and a man that was deeply passionate about the art of cooking.
I learnt from him, at an early age that good food takes time. Not only time to prepare and cook, but to grow, organically and naturally. We often forget that in modern society; with busy lifestyles make that a tricky rule of thumb to follow. But it can be done.
I remember my Dad would make steamed chocolate pudding over a homemade bain-marie, it took hours to cook, but the sweet, sumptuous scent of chocolate would begin wafting through the house in no time, taunting our taste buds and preparing us for what would be a mouth-watering homemade treat.
He also created rich stews that would simmer on the stove most of the day, the flavor deepening with each hour that passed. His food was nothing short of spectacular. I wish I had appreciated it more at the time.
We grew up learning to appreciate food, good food. Wholesome food. My Dad would scorn me in University if he ever saw ready meals in the cupboards. 'They're full of artificial ingredients. You could make better at home,' he used to say…and he was exactly right.
However, going back to busy modern times, I believe that there are some good alterative ready made meals and sauces out there, with a growing abundance of organic and GMO free choices. It's worth the time to read the label at the back and make sure there's no suspicious chemicals or preservatives added.
I wish my Dad was still around today, so that I could talk about food and learn more from him and his extensive culinary background, especially now, as a fully grown adult and passionate foodie. But I will just have to go with what I have already been taught by him already and endevour to expand my repertoire, using him as my inspiration.
Be the change we want to see.
Our buying choices ultimately dictate how supermarkets operate, how farmers manage their crops. Already it's clear that consumers have a massive influence on the market.
It is becoming commonly ubiquitous to find dairy alternatives in cafés, larger whole foods sections in supermarkets, organic isles and smaller franchises, boasting their decision on placards that they opt for organic, local produce. Why? Because more consumers are becoming aware of the real story behind their food and no longer want to support massive companies with low ethics. Instead many are using their consumer power to change the whole food industry. And YOU can do this too!
Supporting food that is grown closer to how nature intended (though I'm still certain most of the Organic fruit and veg grown in the States is still genetically modified to some degree) means less nitrogen and chemical run off into water systems and surrounding soils. It means a healthier and more symbiotic eco-system, something that in the long run, benefits both wildlife and humans.
Let's Talk about the Birds and the Bees
Bees, birds, bats and beetles are some of our chief pollinators, transferring pollen and seeds from one flower to another, fertilizing the plant naturally so it can grow and produce food. [1]Cross-pollination helps at least 30 percent of the world's crops and 90 percent of our wild plants to thrive. And bees are the forerunners in this game.
According to the Natural Resources Defense Council here in the States, [2]nearly one third of all honeybee populations have disappeared. Even back home, [i]more than half of Ireland's bee species have undergone substantial declines in their numbers since 1980. The distribution of 42 species have declined by more than 50%.
[ii]In 2006 an Irish Bee Red List was published. It showed that 30% of Irish bee species are threatened with extinction. Six species are critically endangered, 10 are endangered and 14 species are vulnerable.
Scientists are now calling this Colony Collapse Disorder. A number of factors are believed to be the cause, including global warming; resulting in out-of-season blooming, meaning no food when the bees need it; the use of pesticide on farms, habitat loss from development, growing crops without leaving habitat for wildlife, the planting of flowers that are not pollinator friendly and parasites.
I read somewhere that due to the sharp decline in local native bees and bumblebees, in some of these mono-crop farm belts in the US, people were being employed to simulate what would be their 'buzz pollination' with hand held vibrators on crops such as tomato plants. I have no journal to officially back this up but I have seen various articles online that suggest this is a true fact.
In many agricultural areas, bee colonies are rented to help pollinate plants, with newspapers and agricultural articles complaining about the rising cost of bee rental. .[iii] The almond crops in California are entirely dependent on honeybees, and every spring they require more than half the commercial bee colonies in the nation.
For an interesting and eye-opening read, have a look at http://agdev.anr.udel.edu/maarec/wp-content/uploads/2011/02/Pollination-rentals-PNWEAST.pdf for a list of the rental costs and country-wide demand for bee rentals in the United States.
Bees are so vital to our food chain. We need to protect them for the future of food and our ecosystem.
When did we start using pesticides?
The correlation between the introduction of chemical pesticides in agriculture and the exponential growth in human cancer rates is also far too coincidental to ignore.
When entomologist, Paul Müller first discovered a use for chemical compound DDT (dichlorodiphenyltrichloroethane), it was quickly praised for being one of the most effective insecticide ever seen.
Soon, the idea of spraying food crops with such potent chemicals became a growing, accepted and encouraged trend in the industrial farming sector.
Müller was awarded a Nobel Prize for his work on DDT in 1948. By the mid-1950's it became one of the most widely used pesticides in America. At the same time herbicides were making an impact on agriculture, flogged as some of the best weed killers ever created.
Farming was now turning the tide to become agri-business, rather than agriculture.
How the War made Chemicals popular
Most of these new chemicals in farming came about as a result of chemical warfare during the Second World War. [3]Chemical companies that had produced weapons such as napalm bombs turned their attention to agricultural uses post-war, producing all kinds of new pesticides and a whole new class of organophosphate agriculture chemicals.
Many of these new agricultural chemicals were known to be highly toxic, though many of the effects would not be discovered for many years.
Though many of these post-war, left over chemicals have since been banned in food production, there is still a wealth of known toxic chemicals used today.
Monsanto, a forerunner in chemical agriculture and genetically modified (GMO) seeds has, in recent times, become front-page news the world over, criticised for a strong link between its products and cancer rates in humans.
It's product 'RoundUp', with the widely controversial herbicide chemical glyphosate was finally banned in a number of countries outside the US, such as the Netherlands, Sri Lanka, Columbia and Bermuda, with many EU member states considering to do the same.
[4]'Roundup is one of the most popular weed killers in the world, and it's one of the most common pollutants in soil and water. When a farmer sprays crops with Roundup, the chemical sinks into the ground and leaches into the water. It's in the food that we eat and the water that we drink. The result? Cancer, kidney damage and birth defects – those are just a few of Roundup's effects on our bodies […] Without Roundup, healthy, natural plants would out-compete Monsanto's laboratory creations.'
A RoundUp of Monsanto
On March 25, 2015, the cancer research arm of the World Health Organization announced they had classified glyphosate, the active ingredient in Monsanto's Roundup, as "probably carcinogenic to humans." [5]Monsanto backlash and demands for retraction were immediate.
Aside from the potential carcinogenic effects that chemicals such as Monsanto's Round Up poses, there is also the environmental impact. According to the Pesticide Action Network of North America, the genetically modified, 'RoundUp Ready' seeds produced to grow in such toxic soil (no naturally derived seed could), have, in turn, created an epidemic of [6]glyphosate-resistant "superweeds" now plagues farmers. Weeds develop herbicide resistance quickly.
Cancer Among Farmers
Getting back to the effects of chemicals in farming, scientists from the National Cancer Institute, the National Institute of Environmental Health Sciences, and the Environmental Protection Agency (EPA) embarked a research project known as the Agricultural Health Study (AHS) to evaluate [7]the role of agricultural exposures in the development of cancer and other diseases in members of the farming community (of the United Stated). The National Institute for Occupational Safety and Health joined the study in 2000.
They found that compared with the general population, that whilst some diseases were lower, mostly attributed to their outdoor lifestyle, the rates for certain diseases, including some types of cancer, appeared to be higher among agricultural workers and was potentially related to common work environment exposures.
It was found that [8]farming communities have higher rates of leukemia, non-Hodgkin lymphoma, multiple myeloma, and soft tissue sarcoma, as well as cancers of the skin, lip, stomach, brain, and prostate.
The research conducted was focused mainly on the exposure to the use of pesticides and the link to human cancer. One study in 2009, from the American Health Study revealed that [9]people who use the weed killer Imazethapyr have increased risks of bladder cancer and colon cancer.
Imazethapyr is most commonly used as a herbicide for killing weeds in soybean, dry bean, alfalfa, and other crop fields. Similarly, the risk of colon cancer (mostly tumors in the proximal colon, where food enters during digestion) was nearly twice as high as normal (78 percent increased risk) among farmers who had the highest level of exposure, compared with those who had no exposure to the chemical.
Many further independent studies (those conducted by the big agriculture companies, with a vested interest in their multi-billion dollar products not to be linked to cancers, usually seem to be deemed inconclusive or worryingly concluded as 'safe' for human consumption) have revealed undeniable direct links to these strong chemicals in our food chain to cancer and other diseases.
For a full list of published papers on the study of agri chemicals and the link to disease and cancers (if you are remain defiant against the choice of going organic) take a look at https://aghealth.nih.gov/news/publications.html.
To Conclude
This piece began as a short piece that I felt like writing about, simply because I felt like I was constantly having to justify and defend myself for not wanting to eat meat and opting for organic foods.
As soon as I started to delve, just a little, into the agri-chemical/food industry here in the States, I was overwhelmed by the vast wealth of information relating to the subject. These points barely touch on the dangers of pesticides, herbicides and chemical fertilisers.
However, it has provided, for me, enough rationale for my desire to eat organic and that my reasoning has not been unsubstantiated.
I think if I were to go into the reasons behind why I choose not to eat meat, it might result in a short novel, at this rate!
So for now, I'll just use this piece to explain to all the doubters in my social circle why I choose to eat Organic and why I can fork out that extra bit of money for chemical free food.
I know friends who will easily spend $200 on a handbag but refuse to pay an extra $1 for a chemical-free, naturally grown alternative to their intended veggie list.
I understand that we cannot all buy organic, all the time. But if you can spare an extra dollar or Euro here or there, when you do your weekly shop, it's worth it…For you, for the farmer, for the environment and for the change we want to see in how we're sold food produce.
Support your local farmer. Organic farming is hard work. The yield is often much smaller than that of chemically rich farms. But the food produced is much richer and better for you. This is why it tends to be more expensive.
The more we can buy organic the hope is that it will soon become the norm, as natural farming methods become more widely adopted due to a clear-cut consumer demand.
One last thought…
In the words of Joni Mitchell… 'Now farmer, farmer put away that DDT. I don't care about spots on my apples but leave me the birds and the bees, please'
Empower yourself as a consumer…insist on organic.
[1] Gabriela Chavarria, "Pollinator Conservation," Renewable Resources Journal, Winter 1999-2000.
[2] https://www.nrdc.org/sites/default/files/bees.pdf
[3] http://www.rodalesorganiclife.com/food/when-did-we-start-using-pesticides
[4] https://actions.sumofus.org/a/monsanto-roundup-banned
[5] http://responsibletechnology.org/irtnew/wp-content/uploads/2016/01/2-Glyphosate-Bans-and-Restrictions-Across-the-Globe.pdf
[6] http://www.panna.org/blog/new-pesticides-same-monsanto-story
[7] https://www.cancer.gov/about-cancer/causes-prevention/risk/ahs-fact-sheet
[8] https://www.cancer.gov/about-cancer/causes-prevention/risk/ahs-fact-sheet
[9] https://www.cancer.gov/about-cancer/causes-prevention/risk/ahs-fact-sheet
[i] http://www.biodiversityireland.ie/projects/irish-pollinator-initiative/bees/the-state-of-irelands-bees/
[ii] http://www.biodiversityireland.ie/projects/irish-pollinator-initiative/bees/the-state-of-irelands-bees/
[iii] http://www.slate.com/articles/news_and_politics/explainer/2008/06/rentahive.html


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You like computers. You've always considered yourself pretty tech-savvy. You've even thought that an IT career might be right for you. You just don't know how to get started. Whether you're just considering the field or have already begun to train for an IT career, here are few entry level positions you could aim for:
IT Support Specialist
What you would do
As an IT Support Specialist, you would set up, install, run, and troubleshoot computers and their software. You would maintain systems and all their components and assist with upgrades, service, and repairs and patches. If your company's employees used tablets and smartphones, you might also be the go-to person for frequent updates, installations, and modifications. And you'd be the person teaching all about how the technology works and what to do when it doesn't.
Good to know
Since computers and technology are really important to most companies, your role as an IT Support Specialist is vital. That means there may be days—and nights—when you're on call to handle problems whenever they occur.
Desktop Support Specialist
What you would do
As a Desktop Support Specialist, you'd be focused on the individual computer and user. You would help set up computers and connect them to intra and internets, whether hard-wired or wireless. You might have to set up user computers and accounts, or troubleshoot network, hardware and software issues when things go wrong. If you're a Desktop Support Specialist within an organization, you may only need to travel from department to department. But if you worked for a computer company offering IT support and repair, you might work remotely or onsite to help customers get up and running—and stay that way.
Good to know
If you want to be a great Desktop Support Specialist, keep up with technology trends and be ready to make recommendations on how to incorporate new technologies into existing systems and platforms.
Help Desk Technician
What you would do
Have you ever called a tech help line? The person on the other end of the line seems to know a lot about what's going on with your new computer or program, don't they? That's because they do! If you were a Help Desk Technician, your job would be to provide technical support to users who are having trouble with their computer or its programs. Most Help Desk Technicians never enter someone's home or office; they do all their work remotely. But a few are on-the-go, bringing their troubleshooting skills directly to the end-user.
Good to know
In your role as a Help Desk Technician, your most important job is to diagnose problems. Sometimes they're fixable by you, but sometimes, you'll just pass along your good info to people who are experts.
If you've ever thought about an IT career, start with training from Career Quest Learning Centers. You could earn your Associate of Applied Science Degree in Network Administration in as little as 15 months. Give us a call in Jackson at 877-365-8144 or Lansing at 877-481-4930 to get started now.


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Logan Park Neighborhood Association is holding a community meeting tonight, Oct. 19th at 7pm at Logan Park Recreation Center to discuss the potential development of 807 Broadway NE. As many of you know, the Minneapolis Public School Board is vacating this building next year and moving to a new building in North Minneapolis. The future use of 807 Broadway St. NE is not yet determined. Since this building borders the St. Anthony East neighborhood, we feel it is important to have our input heard on what the neighborhood would like to see happen with the building.
Please attend this meeting tonight and become part of the discussion. This decision will have a significant impact on the surrounding area. Let's make sure the decision reflects what the community wants and will benefit from. We realize this is a hot-button issue for some. However, tonight's discussion will be low key and respectful as promised. Stayed tuned for more updates on this issue. We will post new information as it comes.


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Director: Aurora Fearnley / Screenplay: Aurora Fearnley, Neville Pierce / Starring: David Gyasi, Jessie Buckley, Anna Koval.
a short sci-fi film in which a Peacemaker may well be the harbinger of doom for a spaceship hit with a solar storm. Stunning visuals and an engaging story make this one not to be missed.
Pulsar Trailer from Aurora Fearnley on Vimeo.


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Guide to completing a UK VAT return for businesses using the Flat Rate Scheme
November 2nd, 2015
The following guidance note taken from the VAT module of TolleyGuidance will provide details on what information needs to be included in each box on the UK VAT return. For businesses using the flat rate scheme the guidance note Guide to completing a UK VAT return for businesses using the Flat Rate Scheme should be used instead.
Background to the flat rate scheme
The Flat Rate Scheme is designed to help small businesses by making it easier to record taxable sales and purchases. Businesses using the scheme normally apply a single percentage to their total flat rate turnover in a VAT period and the result is the VAT payable to HMRC. For more information, see the Overview of the VAT flat rate scheme for small businesses guidance note. Please see the Submitting online VAT returns guidance note for more information on submitting the return. HMRC Notice 733; De Voils Indirect Tax Service V2.199D.


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Fertility treatment is stressful and an emotional and physical rollercoaster. You need to be absolutely sure that you have looked at all the options to ensure this is the right route for you.
For instance, IVF won't work for all cases of fertility challenges which is why it is so important to get an accurate diagnosis of why you can't conceive before you start.
Why are you experiencing fertility issues? It's so important to get an accurate diagnosis.
There are a great many causes of infertility, which is why you need the correct medical diagnosis to find out why you cannot conceive. Armed with this knowledge, you can work out the best way forward for you.
If you want to go private (or have to), don't spend thousands on IVF until you've had everything checked out properly.
Download and use our pretreatment checklist to ensure you have had all the necessary blood tests and scans so that you receive the correct diagnosis and resolution. If you have been trying to conceive for a year with no success, take this checklist to your doctor and discuss tests and scans you can have to ensure there isn't an underlying cause.
IVF is not a 'miracle solution'
IVF was originally used to help women become pregnant if their fallopian tubes were the problem, but it's now used because of other causes of infertility, such as ovulation difficulties, low sperm count, PCOS and endometriosis along with, in recent years, preserving fertility.
IVF is not suitable for everyone and it's not a miracle solution.
Consider fertility treatment if it is your only, or your best, option after discussions with your doctor or specialist and remember that there are no guarantees that it will work and, when it does, it will more often than not take more than one attempt to be successful.
Why not visit our First Steps page and Wellbeing page too.
To understand your fertility treatment options, visit Your Journey.
There are also other options available for anyone who does not feel that IVF is right for them, such as fostering or adoption. There are thousands of children looking for their forever family and anyone who may want to find out more should contact their local authority for advice.


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Oh my, received some money long overdue from rpoints – checked my status... They should've removed/unsticked this post years ago.
Skype/pm me if you need any free+unbiased advice re buying/fixing/claiming under warranty (and breaking) any pc/dell or otherwise – i'll reply to all those i remember - i've updated my email.
Was a great community once – pls moderate the rest...
Purpose – to make people aware of their choices and avoid Dell marketing plots to get the best value for money.
Briefly about Dell Inc. - #1 PC manufacturer in the world [offering best v4m assembled PCs/packages on UK market] (ahead of HP and Lenovo) with head office in Round Rock, Texas and manufacturing facilities in Americas, Europe and Asia.
Most of the parts for your new Dell PC (purchased in the UK) are manufactured in Asia – (Taiwan, China, and Malaysia) and PC is assembled in Limerick, Republic of Ireland. (All notebook PC assembly is rumored to be moved to Malaysia in near future). Monitors use parts from Asian manufacturers as well but can be assembled (depending on a model) in Europe, Asia and even the UK (mostly in Malaysia now).
Dell uses in its tower desktops BTX Intel/Foxconn/third party- proprietary (non –standard made to Dell's specs) motherboards NOT interchangeable/upgradable with third party open market-ones. (unless you also wish to replace case and CPU cooling or willing to go for a heavy DIY) – This is not true, however, for Dell XPS 710 and some older XPS models no longer sold, where motherboard can be replaced with similar third party BTX one. Dell now uses standard-design ATX power supplies with all its tower non-slim models.
Dell support/customer services call centers are based in India (not so bad if you talk slowly or to the supervisor).
Desktop choices (home user only):
E5XX : E521 models - very good value4money, relatively easy to upgrade, somewhat limited upgrade options, not suitable for heavy gaming (@ resolutions above 1280x1024). E520 is a better choice due to Core2Duo.
C521 models - not bad value4money, relatively hard to upgrade, very limited upgrade options, not suitable for gaming
9200/XPS 410 - the best value4money Dell currently offers, easy to upgrade, hardly limited upgrade options, suitable for heavy gaming
XPS 210 - the worst value4money Dell currently offers, relatively hard to upgrade, not suitable for heavy gaming (resolutions above 1280x1024), comes with no monitor as standard
XPS 710 - bad value4money, very easy to upgrade, nearly unlimited upgrade options, suitable for heavy gaming out of the box, comes with no monitor as standard
Configuration choices:
- The higher CPU – the better obviously. AMD Live/Intel Viiv-edition for Windows MCE (PC should be configured with a TV tuner/remote or these are intended to buy afterwards – otherwise MCE is hardly useful)
- OS - only pay premium for XP pro if you are a power user (stop reading this now) needing a genuine copy of pro+media or a Business edition of Vista later. MCE – see above or if you have a nice Monitor/TV and planning to use your pc for watching videos on those.
- Support Services – choose 1 year CAR if possible – it is ALWAYS cheaper to purchase an extended/upgraded warranty later if you need it.
- Monitor Depending on whether you can sell the offered monitor it may be cheaper not to upgrade – do your own research. 1600x1200/1680x1050WS – acceptable gaming resolutions available from 20" UltraSharp.
- Memory – the more the better obviously but not from Dell unless it is on a SO. IGNORE 667 memory – you CANNOT change FSB speed in Dell so on 266 your 667 memory would still run on 533 – there is no point to pay more money. It is just a marketing ploy to sell 667 memory (533 becomes more scarce) Dell is aware of this so if you purchased this upgrade – complain and get the difference back. Make sure you have free slots to upgrade – normally at least two out of four are free anyway.
- HDD - same as with memory, but you have only TWO slots (more with DIY/internal enclosures). Ignore RAID setups – (apart of using all 2 available slots) minor boost (if any) in performance does not represent nearly acceptable value4money in RAID0, RAID1 is twice as secure as a single drive and 4 times as RAID0, but home user hardly needs it and again terrible value4money. By the way some of E5xx models are incapable of RAID0 contrary to Dell's advertising.
- Optical – get two only if you do a lot of D2D OF copies. Beware that to upgrade later you would need to buy a SATA optical – pretty rare here in the UK. Again upgrade option with IDE DVD ROM is untrue as all new 5xx and 9200/xps models support only SATA.
- Graphics – ALWAYS cheaper to buy elsewhere.
- Printers – elsewhere, unless free.
- Sound – it is worth to upgrade to MB-integrated SB Audigy + Soft for £12, and X-FI Extreme BUT only if you need it.
- Speakers – A225 set is good for making beeps only. Upgrade to A525 or buy elsewhere. Quality of sound with Audigy is very good and as Dell is a quiet machine and you can enjoy surround speakers fully - not only headphones. Therefore you can spend some extra on a good set of speakers.
- Keyboard – it is worth to get an Enhanced USB Multimedia one.
- Mouse – optical (if free) or a good optical/laser elsewhere.
- Floppy – elsewhere, card reader is okay if you need one – proprietary connection to MB - you cannot install third party ones without rearranging pins.
- Modem, soft and everything else – elsewhere
Later upgrades:
Only unbuffered, non-ECC memory is supported. Slim cases obviously need low-profile graphics PCI cards. PCI-E graphics only – PCI is possible but not worth it..
Good things - Tower cases are easy to open. Easy diagnostics. Very quiet.
Beware - E5xx models have only 305W PSU – unsuitable for high range graphics. Upgrade it if you want something higher than 7950 GT. 9200 – 375W suitable for up to 8800 GTS but may be unstable with it + two hdds + two optical + extra pci cards + usb powered staff.
All new 5xx and 9200/xps models support only SATA – you cannot use your old IDE optical/hdd unless you buy a converter.
Also quietness of your Hell can be compromised by adding a noisy graphics card - try to get one passively cooled (all tower BTX cases are more than capable to cool it) or use aftermarket silent cooler.
Warranty – buy an extension if required around a month-two before your 1 year CAR expires. Over the phone only, haggle hard.
Simple and straightforward – for 'home' use laptop choose 6400 package if you are happy with 15" screen or 9400 if you want 17".
Inspiron 1300 - very cheap, but with Celeron CPU hardly worth attention and represents very low v4m, bulky case, suitable only for light use.
Inspiron 1501 – moderate v4m, in cheap plastic uninspiring case, but competitive (with dual core Turions) – choice of Semprons should be ignored due to low v4m, consider buying at least 1GB of memory (not from Dell) as 512MB would bottleneck due to integrated ATI's HyperMemory graphics (if configured to use full 256MB), VGA out port can be used to connect to TV.
Inspiron 6400 - same bulky-ish case as 1501 but with front multimedia controls and more expandability, S-Video and firewire ports, good/very good value for money with Core2Duo processors – better than similar priced 1501s considering expandability, integrated Intel graphics is a bit slower than 1501's but they both are unsuitable for 3D gaming. (with ATI's x1300 graphics you may actually be able to do some light 3D gaming if you choose). See above re shared memory.
Inspiron 640m - 20 mm smaller (diag) but fatter than 6400 and only ½ kg lighter – hardly portable in my opinion – see it as a lightweight version of 6400 with lower v4m.
XPS M1210 - very good portable package, a bit overpriced but still hard to beat, Dell's power on the move choice if you are happy with 12" screen. Better value than 410 business notebook.
Latitude D420 - Different class laptop – business, though sold in home section. The best Dell's notebook design in my opinion – on par with HP and IBM/Lenovo. Portable, expandable, overpriced. Hard to compare v4m as this is a business laptop – just to say similar spec can be found up to 30% cheaper elsewhere.
Desktop replacement
Inspiron 6400 see above
Inspiron 9400 - that ugly 6400's case got even bigger, better expandability and a lot of functions, nice screen (if you choose UltraSharp that is), very good v4m for 17" home desktop replacement, with Nvidia's 7900gs suitable for heavy gaming (even on an external monitor with AGR via DVI).
Laptop upgrades – it is always worth upgrading screen; battery – if you planning to use it - is a second must, HDD and graphics if needed (7200rpms HDD will improve performance slightly), put aside some funds for the memory if you have only 512Mb pre-installed in your chosen package – it will improve performance significantly (obviously cheaper elsewhere).
Important – there are no PCMCA card slots in new Dell home-user laptops – they all use ExpressCard slot.
There are also on-going issues with Dell's UltraSharp 20+" monitors, where current best-in-class S-IPC (Super In-Plane Switching - LG.Philips see here ) panel being quietly substituted by cheaper and much worse PVA (Samsung's Patterned Vertical Alignment) one. I am yet to hear low quality Dell UltraSharp monitors received by UK customers, but if you did get it – fight. There is a clear description and tech. specification on the Dells website in documents section (that is until they pull it out) so you have good grounds for complaint (PVA simply cannot physically produce quoted viewing angles) – if you cannot find it now/need an old copy – pm me. Read/test your panel here [url].
To get cashback please purchase through links provided in offers posted - see ST's summary here or use my Rpoints link to Dell's site.
Updated 30/01/2007


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A San Antonio-based development group that has been spreading the "Vantage" name to communities around Texas is clearing land next to University High School on New Road to build a $23 million Vantage at Waco upscale apartment complex.
The complex will have 288 units when it is completed in fall 2017.
"We started our 'Vantage' development platform in 2007, and probably have built 24 to 25 properties under that name in that time," co-founder John Condit said. "We like Waco and had been looking for a site there several years before we came across this piece of property."
Traffic passing University High School will notice earthmovers pushing dirt on about 20 acres Vantage acquired in a deal brokered by Waco Realtor Bland Cromwell.
"This is our fifth development now under construction, with others in Corpus Christi, Boerne, New Braunfels and San Antonio's Brooks City Base," said Condit, adding he and partner David Starr recruit investors who help make projects possible from the purchase of land to the final touches of landscaping.
He said Concept Builders, of San Antonio, serves as general contractor for about half the Vantage-branded apartment villages, including Waco's.
Units in Waco will range in size from 575 to 1,200 square feet, and will feature one, two or three bedrooms, faux wood floors, ceiling fans and appliances black in color.
"Waco will get a full amenities package, including a couple of dog parks, a resort-size swimming pool, a workout area and lots of green space for barbecue pits and picnic tables," Condit said. "We're also putting in Waco a concierge service for handling package deliveries, and a special dog wash that works with the touch of a button."
Condit said the company has not yet established rental rates for Vantage at Waco, but will have them in place before it begins marketing the site in May.
Vantage has submitted its plans to the city of Waco, received permits "and now is rocking and rolling," said Bobby Horner, city inspections supervisor.
An uptick in interest
He said the city has noticed an uptick in interest in building or repairing multifamily complexes, especially in the past couple of months.
"I guess they are doing their research and have determined this remains a good market, and I don't see any letup," Horner said.
The U.S. Department of Housing and Urban Development released an analysis April 1 of the Waco housing market showing demand for 1,375 rental units and 800 units under construction. It also noted that during the 12 months ending March 2016, the overall rental vacancy rate was 7.6 percent, down from 9.2 percent in 2010.
It said the drop "is because of an increase in the number of students at Baylor University who reside off campus."
On the west side of Interstate 35, also on New Road, construction is winding down on the $25 million Tuscany Ranch Apartments, which is 284 units spread over 22 buildings and 11 acres, with the units leasing for $899 to $1,399 a month, depending on size and amenities. Community perks include a resort-style pool fed by fountains, a 24-hour fitness center, a dog park, courtyards, a clubhouse and internet cafe with gourmet coffee and tea, according to the company website and spokesman Scott Case.
This is the 20th apartment undertaking in Texas for Tulsa-based Case & Associates, which Case said prefers to build in college communities.
The Tuscany Ranch rental office said 82 apartments have been leased, and 52 are now occupied, even as finish-out continues on part of the complex.
"I bet they will be filled by the time we complete construction on Vantage at Waco," said Condit, adding he does not think Waco is getting too many apartments.
"You're really behind, I believe, because I think national developers have overlooked Waco. We didn't. We were looking for years before we found the right piece of dirt."
He said Vantage looks at employment figures, ease of transportation and the quality of schools when choosing a market to enter. It is not targeting a particular demographic group with Vantage at Waco, he said, and instead expects "the entire spectrum of residents, including students, young professionals and retired folks."
Also in South Waco, Wisconsin-based Continental Properties is building 280 apartment homes in the 4900 block of Bagby Avenue, across the street from Cottonwoood Creek Golf Course. Pre-leasing reportedly has begun at Springs at Cottonwood Creek, and occupancy may begin as early as January 2017. Lease rates range from $900 to $1,500 a month, and amenities include a community clubhouse, resort-style swimming pool, free Wi-Fi, coffee bar and car-care facility.
Cromwell, who brokered the sale of the acreage to Continental Properties, said developers going up with new multifamily units know what they are doing.
"They are very seasoned, very good at their own analysis of supply and demand, and they are convinced we need more units," Cromwell said.
Most in decades
Jim Lapides, spokesman for the Multi-Family Housing Council, which represents large apartment owners, managers and developers nationwide, said the trend being perpetuated in Waco is one impacting communities of every size around the country, "where we're seeing more apartments under construction than we've seen in decades."
He said percentages of the 80 million millenials and 77 million baby boomers are either entering the housing market for the first time or downsizing.
"We estimate the country needs 300,000 to 400,000 new apartment units each year to meet demand, and in 2015, 310,000 apartments were built," Lapides said. "That's the first year in many that we've met the bottom end of that spectrum, and since nothing was built during the last recession, there is a lot of pent-up demand."


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The big corporations did that to you. The 1 percent did that to you. We need to be the party of working people, and that includes a party of immigrants. But first we have to tell working people in America who are hurting that we're going to be on their side every single time against those big corporations who created this mess to begin with. And remind people we're all in this together.
If we don't change that debate, that politics that's holding us back, we won't get all these reforms people are talking about. That's what we need to do as Democrats.
So we need to have a different conversation in this country about guns, but also a different conversation about policing that brings police and community together. We've done that in New York City and we've driven down crime while we've done it.
O'ROURKE: No. I think the choice is fundamental to our ability to get everybody cared for. Our plan says that if you're insufficiently insured, we enroll you in Medicare. But if your health care plan works for you and your family, you're able to keep it.
DE BLASIO: Wait, Congressman O'Rourke; private insurance is not working for tens of millions of Americans when you talk about the co-pays, the deductibles, the premiums, the out of pocket expenses. It's not working. How can you defend a system that's not working?
O'ROURKE: That's right. So for those for whom it's not working, they can choose Medicare.
DE BLASIO: You've got to start by acknowledging the system is not working for people. You are defending private insurance.
Rep. Beto O'Rourke: Yes, but that action should always be undertaken with allies and partners and friends.
DeBlasio: What about the War Powers Act being a part of that equation? With deep respect to the congressman, look, we've learned painful lessons as Americans that we've gone to war without congressional authorization. Even in the humanitarian crisis--and I think we should be ready, Congressman, to intervene, God forbid there is genocide--but not without congressional approval. Democrats and Republicans both in the Congress have not challenged presidents and have let them get away with running the military without that congressional approval. We learned a lesson in Vietnam we seem to have forgotten, that decisions have to be made by the United States Congress.
The above quotations are from NBC News, "Decision 2020," the Democratic candidates debate,
live from the Adrienne Arsht Performing Arts Center in Miami, Florida, June 26-27, 2019..
Click here for main summary page.
Click here for a profile of Bill de Blasio.
Click here for Bill de Blasio on all issues.
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text:
Canpaigners hoping to save an under-threat Rhondda primary school have lost their battle after the council's cabinet members voted to shut its doors for good.
Children, parents and governors of Aberllechau Primary School went to Rhondda Cynon Taf council's headquarters in Clydach Vale on Thursday morning, hoping members would make a sensational U-turn and keep the Wattstown school open after a Statutory Notice for its closure was published on October 10.
But members unanimously voted the "underperforming" should close – to the fury of those in the public gallery – and it will now do so on December 31 with pupils and its Learning Support Class transferring to Pontygwaith Primary School.
The school staved off a similar proposal for closure in 2009, but its future was once again put in danger when the director of education for RCT, Chris Bradshaw, earmarked the school for closure in May due to falling standards.
This was followed by a campaign of opposition by parents who had a number of objections – among them that the school had not received adequate help since 2009, that the walking route from Wattstown and Pontygwaith was too dangerous and that the school is at the heart of its community.
At Thursday's meeting, cabinet member for education and lifelong learning Eudine Hanagan said: "This is a very difficult decision because people living in Wattstown think it is a part of their community, to keep the school there.
"The children there are capable and can reach very high standards if they have support."
Mr Bradshaw added: "Aberllechau has struggled to be an educationally viable school and will continue to do so without council support."
He also confirmed there are available places at Ynyshir Primary School – in reception class through to Year 6 – if some parents would prefer their children to be taught there. But there are not enough spaces for the whole school to transfer.
Council leader Andrew Morgan added: "Unfortunately the school is failing. I can absolutely, categorically say that this has nothing to do with finances – it does not make any financial saving.
"The school is in Special Measures. Estyn made it quite clear they expected action."
Local councillor for Ynyshir Lionel Langford said he opposed the move.
He said: "The school has been at the heart of the community for many years – to lose it would be a tragic event for all the people of Wattstown.
"The price of education is not worth the value of a child's injury or life. I ask you to reject the proposal."
As part of their campaign, parents and pupils marched en masse from Aberllechau to Pontygwaith school in June – the route they will have to walk each day – to highlight what they feel is a "long and dangerous" journey on foot.
The proposals, which cabinet members passed on Thursday morning, include highways improvements to address those concerns.
Two raised zebra crossings with "associated build-outs and street furniture," as well as road markings and traffic signs, will be implemented along Margaret Street and Aberllechau Road.
An introduction of a 20mph speed limit along Madeline Street close to Pontygwaith Primary will also be introduced, alongside informal pedestrian crossings through dropped kerbs.
However, the report says these changes may not be completed by January 5, when children are set to return from their Christmas holiday, due to inclement weather conditions.
If they are not completed, a 'walking bus' will be introduced in partnership with South Wales Police to ensure the safety of pupils and parents walking to from the Wattstown area to Pontygwaith Primary.
Coun Langford added: "If the weather is too bad for them to dig up the roads, that same weather will affect children walking to school. The idea of the walking bus is nonsense."


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We are the lucky stewards of three unique pinot noir producing vineyards in Summerland, BC. Each of them express very distinct terroir through the wines, despite being located mere kilometers apart.
Elysia Vineyard - Planted in 2006, this vineyard overlooks Okanagan lake to the east, primarily getting the early and mid day sun. Between the very steep slope and a mix of limestone and decomposed granite soil, this is an ideal place for vines to thrive. Here we have Pinot Noir, Viognier and Syrah. We are able to make a variety of delicious wines. With panoramic views from Peachland to Penticton it is a truly amazing place to work and live.
Canyonview Vineyard - Planted in 2003 on the precipice of the Trout Creek Canyon, this vineyard has been immaculately cared for by Garth Purdy from day one, and he continues to do so. This south facing vineyard has sandy soil that is dotted with large granite stones, producing spectacular Pinot Noir and Chardonnay from two large terraces.
St. Katharinas Vineyard - Planted in 1968 this was one of the first vineyards planted with Pinot Noir in Summerland and the Valley. Located on a south-east facing terraced slope, this vineyard lay untended for over 7 years. Through a minimal pruning and lots of love we are bringing it back into production. This wild place only receives 2 deep watering's a year and the plants resemble small trees who have come into their own natural balance. Truly a one of a kind.


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TROY — At Monday's Troy City Council meeting, President Marty Baker asked questions regarding the transport of patients by city medics as the Kettering Health Network Troy Hospital plans to open on June 18.
Director of Service and Safety Patrick Titterington said the Troy Fire Department follows regional protocol to transport a patient to the nearest healthcare facility.
Baker also asked if the hospital's helipad, which is street level, would impact drivers with possible "rubbernecking" issues and traffic safety.
"We are not aware of any additional needs related to the helipad, as that is all regulated by the FAA through Kettering Health Network. We are checking further with KHN security personnel," Titterington said.
Baker said the questions came from local residents regarding the new hospital's impact on resident services.
In a press release from the city, Troy City Fire Department Matt Simmons addressed Baker's questions regarding its medical transportation protocol.
"The Troy Fire Department transports all of our patients to hospitals based upon the guidelines set forth by the Greater Miami Valley EMS Council. These guidelines are our operating protocols and are administered under the direction of our medical director," Simmons said. "Under these protocols, the Troy Fire Department transports all of our patients to the closest and most appropriate hospital, which will normally be Troy Hospital on West Main Street.
Simmons said the fire department will take into consideration the preference of the patient and pre-existing conditions or ongoing treatment unless any of the following conditions are present:
• It is medically necessary to transport the patient to the closest hospital for stabilization.
• It is unsafe to transport the patient to the preferred/recommended facility due to adverse weather or ground conditions or excessive transport time.
• Transporting the patient to the preferred/recommended facility would cause a critical shortage of local EMS resources.
"In certain situations, including special pediatric emergencies, special cardiac or stroke emergencies and trauma emergencies, our crews would transport to the appropriate facilities specified in our protocols," Simmons said.
If there are any questions, contact the Troy Fire Department at (937) 339-0495 or visit the city's website http://troyohio.gov.
Reach Melanie Yingst at firstname.lastname@example.com
© 2019 Miami Valley Today, all rights reserved.


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The secret to preserving your engine's quality performance is quality lubrication of its metal parts and a consistent oil change schedule. Okay, it may not be a secret but too many vehicle owners underestimate the importance of the oil change schedule. If you can't remember your last oil change, it's definitely time to give the team at P&A Smith Auto Maintenance a call. We'll consider your vehicle's age, your driving habits, and the manufacturer's recommendations when designing your oil change schedule. We understand that auto maintenance services may not be at the top of your to-do list, but our customers can enjoy their visits to our facility. Our quick and clean oil change services will keep your vehicle running smoothly and efficiently. Spending less money at the gas tank and protecting the engine from friction and overheating are just two of the benefits of our quality oil change schedule.
The engine is the most important part of your vehicle which makes the oil change the most important maintenance service. We use the best quality brands of motor oil and the appropriate grades of motor oil for your vehicle. Filter changes should also be on a consistent schedule, often necessary at the same time as the oil change. We'll let you know when and if we need to change your oil filter change. This is part of the complete oil maintenance service that you receive from P&A Smith Auto Maintenance. Our team will prevent your engine's early retirement. Vehicle owners often don't realize that their vehicle's engine is in bad shape until they try to sell it, or after it breaks down. Let us keep you two steps ahead of any performance issue with our top quality oil and filter changes. We keep your services quick and affordable to protect your vehicle's engine, its overall performance, and its resale value.
Time for another oil change? Start with the team that handles every complicated auto repair and every routine maintenance service with the same commitment to excellence. Our close attention to detail ensures that you receive the best maintenance services possible. We employ a friendly team of service professionals that are waiting for your call or your visit. Our quality oil change services have been keeping Cary motorists on the road since 1986. The reason our customers keep coming back to us for oil change service is that they've grown to trust our expertise. Give us a call today at 919-467-7016 to schedule your next oil change. You can save time by using our convenient online scheduling system right now. Next time you're in the area–130 Woodwinds Industrial Ct.–feel free to stop by for a quick and clean oil change.


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It's been a while since I've written one of these – I kept thinking I should, but then realized I had nothing to write about. No words. That happens sometimes – there just isn't anything to give.
So here we are – next week, on Friday September 22 – the autumn equinox. Goodbye summer, hello the slow progression into winter. For those of you who live here in Kodiak with me, it's like we never even had summer anyway. About halfway through August I decided to release expectations, and just hope for the best for fall – amiright?
Honestly though, for my whole life, fall has been my favorite season. I grew up in New England, the land of glory this time of year – crisp sunny days, cooling temperatures, bright red and orange and yellow leaves, apple picking turned into pumpkin picking. I looked forward to it every year, and I still do.
Why, you might ask. Yes, it does signal the coming of winter. The death of flowers and green leaves, the loss of vegetation, the retreat of the animals, the inevitable arrival of the cold, the brown and the decomposition and the dark. None of that is lost on me. But despite that, I have continued to adore this time of year more than any other.
Last weekend, I took a drive "out the road" (Kodiak peeps, you'll know what I mean – and for the rest of you, when you live somewhere where everything you need is within a 14 mile radius, sometimes going for a drive is quite relaxing and enjoyable – also note, no traffic) while sipping a hot coffee, and again was comforted by the signs of coming autumn. Kodiak is the greenest place in the world during the summer, and don't get me wrong – its astounding. They don't call it the Emerald Isle for nothing. But I can't help it. I love the brown and the yellow and the deep reds. The multilayered hues of the mountains as they retreat into the distance. The wisps of white silk that replace the purple fireweed flowers. Goldenrod that surely signals the coming of fall. Even the dried leaves that scatter the road after being released from the trees. EVEN the shortening days. I have been embracing the returning darkness with open arms.
So why this love of all this dying?
Sure the colors and the smells and the festivities and warm spiced drinks – all that is wonderful. But I am now realizing that it is so much deeper than that.
In yoga, there is a term called prana. It is not something you see, but something you feel. Our life force. Our energy. That invisible inner flow that keeps us going. I think you can all agree that sometimes we have those days that we great, and those days that we feel awful. And I don't mean we stayed up too late and had an extra glass of wine (if you ask me, that is only something that adds to our life force 😉 No, I mean the difference between inspired versus dull. Content and fulfilled versus restless and unfocused. Those days that your cup is so full that you feel you can give endlessly, versus those days when you feel that you couldn't possibly be selfish enough. I think you get what I mean.
Since I started on my yoga teaching journey, I have become deeply in tune with my life force. With the importance of filling my cup – whether that be a yoga practice, a hard workout, or alone time. Being aware of those situations, or activities, or people, that drain me, and giving myself permission to avoid them. With the importance of saying "no" when I mean "no". In short, conserving my energy for MYSELF. What a concept. And this is not solely selfish. Conserving energy, so that I am fulfilled, and in turn can serve and fulfill others. I have learned (and am continuing to learn) exactly how to take care of myself, listen to what I need, value solace and my own good company – because all in all that MAKES ME A BETTER PERSON. As my teacher has said – "Conserve your prana. Don't let it leak out." Keep that shit in.
So here I was, driving down Chiniak Highway enjoying my latte, and it hit me. Bam. After 31 years, I connected the dots. I love fall so deeply, because it is Mother Nature's way of conserving HER prana. She has emerged in the spring, slowly blossomed, flourished in all her colorful, brilliant glory, and put on quite a show for us to enjoy. And then, she knows exactly when enough is enough. When to curl up the proverbial red carpet and stop the show. When to let go of the outward beauty, and worry more about what is going on inside. Why? Because that is the natural cycle of energy. A period of dormancy and inner nourishment leads to the ability to blossom; when all the energy is expended, the retreat into dormancy, the saving up, for the next cycle of offering. So that next spring, she can do it again, fully and completely. So that she may continue to offer her beauty year after year.
Mother Nature, you wise thing, you. We should be more like her. If we give and give and give, we will soon be so empty ourselves that we have nothing left to draw from. We live in a society that constantly demands us to live outwardly. We are pulled in many directions, and often feel that we need to put others' needs first. After so much of this, we become dull and drained, and physically and emotionally we take the toll.
BUT when we can learn to offer ourselves what we need (for me, that quiet alone time that is so deeply fulfilling) we regain our energy and life, our PRANA. So it now makes sense to me – I love autumn, because I align with this deep need to retreat and turn inward, so that I can be more vibrant and offer my gifts to the world.
So I invite you to carve out some time and figure out just what YOU need. What fills your cup? Physical movement? A walk? Some quiet time to sit and stare? (I feel ya – sometimes that's spectacular). Make time for that. THERE IS ALWAYS ENOUGH TIME IF YOU MAKE IT. Take five minutes at your desk to do some stretching. Forgo watching your show in the evening and sneak out for a walk instead. Arrive five minutes early to pick up your kids at school, turn off the radio, and enjoy the silence and pulse of your breath. It's hard – I get it. I've been a single mom for almost this entire year. BUT – when you take the time to fill your cup, all that adulting feels easier, and maybe even joyous.
Where can you say "no"? What can you let go? What is not necessary and does not add beauty and joy to your life? Begin to take note of what/where/who drains you – with no apologies. It's okay. We don't have to do it ALL. There is always an engagement, a social situation, a chore, you can choose to forgo. I promise that will not make you a bad person. Even just one 30-minute task per week – it's amazing the power of "no" – when it opens up more time for us to go inward. To keep that shit in.
So be like trees. Sometimes we just don't have anything to give – and that is okay.
Peace and love.


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Timken 30313-90KA1 Tapered Roller Bearin
Timken 30313-90KA1 Description . 30313/92KA1, Tapered Roller Cone & Cup, Bore Dia.: 65mm, Cone Width: 33mm, Cup Width: 28mm, Inner Ring Width: 33mm. ... 30313-9aka3 timken 96925-90071 timken k.81114lpb timken t58663 32020x-90ka1 timken a5144 prec.3 timken k18x22x22fkiv1a timken tw134. GET PRICE BY E-MAIL.
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Upper Material : Breathable Mesh Outsole : PVC Insole : Super Soft Lace Material : Nylon
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ARMANI BEAUTY Eye tint eyeshadow
Product information
Discover Armani Eye Tint, our iconic liquid eyeshadow. Playful and intense, these long-lasting, crease-proof eyeshadows combine the purity of a powder with the feel of a cream for up to 16 hours of smudge-proof colour.
All of the Eye Tint shades feature dynamic runway-inspired colours that can be used as eyeshadows, eyeliners, or highlighters. Finishes include: Smoke, Satin, Acqua and Chrome.
- Mistake-proof application
- Long lasting - up to 16h
- Multi uses product - eyeshadow, eyeliner and even highlighter
- Suitable for all skin types and ages.
Brand information
Armani BeautyPurchase experienceDelivery experienceUnited Kingdom delivery (see more)Minimum order for free delivery £0.00Free standard delivery on all ordersEligibility for returns 14 days
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Meet The Feds: Part 3…..Understanding the Coming Threats
This is the last 10 minutes of Day 1 at TechEd 2008 for Agent Lynd and I. In this wrapup, Agent Lynd covers some of the trends in the security landscape and some of the things that IT Pros need to be to be watching for going forward.
Next time I'll load up the video from the Day 2 episode, where we sat and talked with Supervisory Special Agent Tim Stranahan, a Counter Intelligence agent, from the FBI Charlotte office, on the threat that is industrial/economic espionage from both foreign countries and internal employees. It's a great session, so please check back.


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Gift Vouchers
Please select from the available vouchers below.
From 30 minute taster sessions at £21 to 2 day courses from £175 there is something for everyone.
To order a voucher for a specific amount enter the quantity in the box next to the £1.00 voucher below. For example if you want to order a £21 voucher, enter the quantity as 21.
When you are ready to plan your session call us at the centre on 01545 561257 and quote your order ID to make the booking.


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The men's lacrosse team cemented their spot in the Big Ten tournament this past weekend with a victory against the University of Michigan Wolverines on Saturday, thanks to yet another last minute goal by junior attacker Kyle Marr. The Jays take on the University of Maryland Terrapins this coming Saturday, which will determine who gets the No. 1 seed heading into the Big Ten Tournament the following weekend.
Though the Blue Jays never trailed against Michigan, the game was anything but easy, as Hopkins squandered two three-goal leads through 60 minutes of play. The first came right at the start, as Hopkins scored three unanswered goals from three different players — Marr, senior midfielder Patrick Fraser and senior midfielder Joel Tinney, within the first four minutes of the game.
Michigan would take advantage of a man-up opportunity in the first quarter for their first goal with just under eight minutes to go in the first. The Jays' offense would be shut down by Michigan for the rest of the quarter, giving the Wolverines the opportunity to tie it up with two unassisted goals to end the first quarter.
The second quarter was a defensive battle, with only a combined three goals being scored by both sides. Marr scored the first of the three goals in the quarter, thanks to an assist from Tinney. But Michigan responded on another man-up opportunity, tying the game at four as junior Brent Noseworthy scored his second goal of the game for the Wolverines.
Senior goalie Brock Turnbaugh played a key role for the Jays throughout the game, playing some of the best lacrosse of his career this year.
"It's senior year. There is no next year for me. I have been making lacrosse the best part of my day and enjoying the time I have left with the guys. At the end of the day, I am simply having fun playing the sport I love," Turnbaugh said.
It looked like the game would remain tied at the half, but Fraser scored his second goal of the day with just six seconds left in the first half to put Hopkins up 5-4 heading into halftime.
Fraser and the rest of the Jays would carry the momentum into the second half, as Fraser opened the scoring on a man-up opportunity less than four minutes in. Marr would then match Fraser's hat trick with one of his own to give Hopkins their second three-goal lead of the game, this time at 7-4 with under five minutes to go in the third quarter.
Michigan, however, responded once again, scoring three unanswered goals of their own in under five minutes, spanning from the end of the third quarter into the beginning of the fourth. With the game tied back at seven, the teams began to trade goals in the fourth quarter.
Tinney ended the Wolverines' run with an unassisted goal with 13 minutes left on the clock. Michigan scored their response goal with just over six minutes remaining, but senior midfielder Brinton Valis had his own response, scoring his 13th goal of the season just over a minute after the Michigan goal.
With one minute remaining in the game, Noseworthy scored his fourth goal of the game for Michigan to tie the game up again. The elation Michigan fans felt was short-lived, however, as Michigan violated the following faceoff, their third such violation of the half, thus giving Hopkins a man-up opportunity for 30 seconds.
The Jays would take advantage. At 31 seconds left, Marr matched Noseworthy yet again with his own fourth goal of the game, thanks to an assist from Tinney — his fourth that game. That goal ended up being the difference, as the game ended with a final score of 10-9.
The last-minute goal by Marr is his second game-winning goal with less than a minute left this year. In the Blue Jays' game against Rutgers University, Marr scored with 14 seconds left on the game clock and only one second left on the shot clock to secure a 13-12 victory.
"Our coaches do a great job during the week getting us ready to go for any scenario that may come our way, and if you happen to have the ball at the end of the game, you know you are prepared to capitalize for the whole team," Marr said.
The faceoffs on Saturday were also a key part of the game, even before the final faceoff violation that cost Michigan the game. They were heavily dominated by Hopkins, as senior faceoff specialist Hunter Moreland won 17 of the 23 faceoffs in the game.
The four goals by Marr give him 27 on the year, which is second best on the team, and Tinney's four assists give him 28 on the year to lead the team. Turnbaugh contributed 11 saves, putting up double-digit saves for the third straight game.
"Moving forward, I think the biggest key for us is to play a consistent 60 minutes in every game we have. At times, we have put together three quarters, and it has been enough, and at other times it has not gotten the job done," Marr said. "This late in the year, it's even more important that we put together a full game, because you never know when your last game is going to be."
The win improves the Jays' Big Ten record to 3-1, putting them in a tie for first place with the Terrapins, the team they will play at home in their final regular season game. Whichever team wins that game will be guaranteed the No. 1 seed the following weekend in the Big Ten tournament, so be sure to come out and support the Blue Jays on Saturday, April 28 at 2 p.m. at Homewood Field.


text: Tickets: $16 presale/$20 at the door/$25 reserved seating Purchase tickets at *March 31 and April 3 performances are Pay-What-You-Can**April 5 performance is $20 presale/$25 at the door and includes complimentary beverage, light bites and closing night festivities. For more information please visit www.freneticore.net. FrenetiCore presents WIRED: Dance+Technology at Frenetic Theater, March 28-April 5. Streaming bodies. Athletic intelligence. A visual feast of choreographic surprises. WIRED is a series of individual screenshots roaming our current technological reality. Projection mapping, video, lighting, props, and sound effects merge seamlessly with raw, live movement. Emotion is illuminated through physical and technical design in a high-energy, visceral examination of human experience. Gather around our digital campfire and enjoy the unfiltered technology of the human body. Choreography by Rebecca French and FrenetiCore dancers.Video and projection mapping by ears are good. Photography by Les Campbell. Technical direction by Edgar Guajardo. Cast includes Danielle Artis, Madonna Bauch, Adam Castaneda, Dorianne Castillo, Rebecca French, Jaime Garcia, Lauren Hurstell, Taylor Martin and Mollie Miller. WIRED also features performances by guest companies Cirque La Vie (March 28-31) and jhon stronks' 'there in the sunlight' (April 3-5). Cirque La Vie With a contemporary approach into the world of circus arts and dance, Cirque La Vie takes the audience on a mysterious journey of the human body and strong apparatuses, where one cannot work without the other. Cirque La Vie unites artists on film, photography and stage. http://cirquelavie.wix.com/cirquelavie 'there in the sunlight' #FeedBackLoop for Bodies, Electronics and Voice is the embodiment of cause-and effect chain between artists Jeremiah DiMatteo and jhon r. stronks. Activated through real-time vocal and electronic music production, this chain forms a circuit in which information from each artist's past or present influences the same phenomenon in the present or future. The continuous looping of feedback provides mechanisms for controlling the running, maintenance, and evolution of a work that reveals the common ground created in over lapping without the demand 'sameness'. www.thereinthesunlight.com Log in | Site Map | Feed | Schipul Web Design | Tendenci ® – Open Source For Associations and Nonprofits Source.


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Questions about our programs? Please contact the Office of Graduate Admissions to request more information, answer questions about programs and to help guide you through the process of applying to our graduate programs.


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Condesing Plumes
The ETA ERA begins by removing a gas stream from the stack or duct. This sample is ported via a heat traced sample line (containing a thermocouple) to the Plume Simulation Chamber. The sample first enters the primary dilution chamber. The dilution gasses are conditioned through a series of temperature and relative humidity determining steps. The sample gas combines with the dilution gasses in the Primary Dilution Chamber (PDC). Once the gasses have mixed, they travel through one or more Mixing/Reaction Chambers (MRCs). The MRCs allow the reaction to proceed before the combined gas streams are hit with a second quantity of dilution gas. Once the secondary dilution air is introduced, the gas stream proceeds through another series of MRCs. This gives the secondary combined gas stream (SCGS) time to complete condensing or reacting before entering the Transmissometer .
The Transmissometer (LDT) receives a portion of the SCGS from the final MRC. This enters the LDT and heads toward the center of the Optical Sample Cell. From the center, the SCGS heads into the condensables collection chamber where it exits the system. Any material that does condense in the LDT Optical Sample Cell falls into the condensables collection chamber and is pumped out by a peristaltic pump.
Eastern Technical Associates, PO Box 1009, Garner, NC 27529-1009. Tel: 919-878-3188; Fax: 919-872-5199.


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3 to 4 hours
Guadalajara , Mexico
2 ~ 15
Awesome content
Visit a local Craft Brewery in Guadalajara metropolitan area. Experience a real cultural and educational tasting. Learn about the history, raw materials and production processes of Mexican craft beer in a fun, social and friendly atmosphere. Taste more than 6 different types of local and regional craft beers. Enjoy also beer pairing, gourmet snacks and the incredible knowledge of the local brewing experts.
- Location of Tour: Jalisco, México.
- Tour City: Guadalajara
- Tour Neighborhood: Colonia Americana & Santa Tere
- Tour Duration: 3 to 4 hours
Start time: 17:00 hours
- You'll be picked up at your accomodation
- Visit and tour a local craft brewery
- Enjoy an educational tasting assisted by a beer expert
- Try several different samples of craft beer with pairing and gourmet snacks
- Learn about the traditions of craft brewing
- You'll be droped off at your accomodation
Eligibility criteria
- Person over 18 who can drink
- Minimum number of people : 4
- Maximum number of people :15
- Availability: Monday to Friday (Requires reservation 48 hours before due to production times)
What's Included
- Guided visit to a craft brewery (Factory subject to availability)
- Visit to a craft beer Tasting Room & Pub
- Educational Guided Tasting (several samples of craft beer with pairing)
- Round of Questions with beer experts
- Gourmet mexican snacks
- Round transportation (Hotel, Hostel or Airbnb)
- Private transportation in between every stop
What's not included
- Open Bar
- Tips
- Food (You can request it with additional cost)
- Rain Season from May to October
- Comfortable clothing and shoes


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You might have heard of SHALMIAK before in connection with creative designs and colorful fabrics. SHALMIAK has literally turned a new leaf and now develops high quality loose leaf teas with pure ingredients coming from the clean and beautiful Finnish nature.
SHALMIAK combines the best ethically and naturally produced teas from the East to the unique berries and fresh herbs from the West (=in this case meaning Finland). SHALMIAK relies on simplicity and uses only a handful of real ingredients in its teas – nothing fake, pretend or extra.
These unique teas are packed in little boxes handmade sustainably of PEFC-certified Finnish pine wood. These boxes are little treasures that can be used to store teas or anything else. But when it is time to discard them they won't leave any traces behind. SHALMIAK considers every detail of its products with respect for nature.
SHALMIAK tea includes…
- high-quality tea – ethical and natural
- Finnish berries and herbs known as superfood
- wrapped in a compostable NatureFlex bag to ensure freshness
- packed in a box made with high quality Finnish craftmanship, PEFC certified Finnish pine wood and unique Finnish design
- sealed with kraft paper labels made of recycled material
However, it is not just about tea. It is about experiencing authentic tastes and scents from the unique Finnish nature… Every box is a little piece of Finland. Enjoy it with all your senses and make every sip of tea a moment you will always remember.
Have a sip of Finland…
Best wishes,
SHALMIAK / Sari Ahokainen