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Study of animal suicide can help humans, researchers say
Animal Suicide
Recently published research suggests that animal suicide can help explain why humans take their lives, writes Larry O'Hanlon in Discovery News.
There's a long history of animals behaving suicidally — think of whales beaching themselves. There have even been cases of forlorn family pets drowning themselves.
If animals can be self-destructive, they could also then help us to better understand the same behaviors, according to researchers at the University of Exeter in the U.K. and the University of Manchester.
"It's incredible how actually pervasive (suicide) is in nature," said psychologist Thomas Joiner of Florida State University, author of the book Myths of Suicide. He said organisms of all sorts are known to self-destruct in one way or another, usually in order to protect their relatives — and so to save their genes.
Pea aphids, for instance, when threatened by a ladybug can explode themselves, scattering and protecting other aphids and sometimes even killing the ladybug. They are literally tiny suicide bombers, Joiner told Discovery News.
What Dog Growls Mean
Dogs understand the meaning of different growls, according to a Hungarian scientist.
In 2008, Péter Pongrácz, a behavioral biologist at a Budapest university, monitored dogs' heart rates to show that they seem to notice a difference between barks aimed at strangers and those directed at nothing in particular. Now, he has gone a step further and shown that dogs respond differently to different vocalizations, according to an article in Discovery News.
Pongrácz's team recorded growls from 20 pet dogs in three different situations: a tug-of-war game with their owner, competing with another dog for a bone, and growling at an approaching stranger. Growls may convey more meaning than barks, says Pongrácz: wolves rarely bark, and he says dogs may have learned to bark to get human attention.
The team played the recordings to 36 other dogs that had each been left to gnaw on a bone. Only those that heard the food-guarding growls tended to back off from the bone and stay away.
"It seems dogs can understand something about the context," Pongrácz says.
Dogs With Bad Teeth
Banfield's Applied Research and Knowledge (BARK) team has released new findings to help pet owners maintain and improve the health of their dogs' teeth, according to petpeoplesplace.com.
The findings show that periodontal disease is the most common disorder affecting cats and dogs worldwide, and informal estimates put it's prevalence as high as 85 percent.
According to their latest findings, certain breeds are more predisposed to periodontal disease than others. The 10 breeds most predisposed to periodontal disease are as follows:
— Toy Poodle
— Yorkshire Terrier
— Maltese
— Pomeranian
— Shetland Sheepdog
— Cavalier King Charles Spaniel
— Papillion
— Standard Poodle
— Dachshund
— Havanese
The U.S. Food and Drug Administration (FDA) urges pet owners who shop for prescription pet medicines online to make sure of exactly what they are buying, according to Pet Product News.
There is no foolproof way to tell if an online pharmacy is legal, according to the FDA. To help pet owners protect their pets, the agency provides the following guidelines:
Before buying online, talk with a veterinarian. Some questions the FDA suggests are: "Do you trust the internet pharmacy site?", "Have you ever worked with the company?", and "Have other clients used that site?" If any of the answers are "yes," what were the veterinarian's experiences?
Watch for red flags. Some warning signs the FDA points out include: the site does not require veterinary prescriptions for prescription drug orders; the site has no licensed pharmacist available to answer questions; the site does not list physical business address, phone number or other contact information, the site is not U.S.-based; the site is not licensed by the State Board of Pharmacy where the business is based; the site does not protect your personal information.
Always check for site accreditation. In 2009, the National Association of Boards of Pharmacy (NABP) created a voluntary accreditation program called Vet-VIPPS (Veterinary-Verified Internet Pharmacy Practice Sites). This program helps identify online pharmacy sites legally selling veterinary prescription products.
Report problems and suspicious online pharmacies.
If a pet has a problem with a medicine purchased online (for example, a reaction to the medicine), first contact the medicine's maker. To report adverse drug events directly to FDA Center for Veterinary Medicine (CVM) call 1-800-FDA-VETS.
Tag Day
The American Humane Association is celebrating Every Day Is Tag Day™ on April 3. This annual event encourages all pet owners to tag and microchip their cats and dogs so that a lost animal has a better chance of returning home if the unthinkable happens. "Most lost pets without identification are never reunited with their families," says Dena Fitzgerald, American Humane's program manager for publications and external communications. "At the very least, every cat and dog needs a collar and ID tag, but the best solution is to also microchip your pet for permanent identification."
Reach John Davidson at email@example.com


text: Deviations from coaxiality, i.e. the difference between the centre lines of the shaft and housing bore (shaft-to-bore misalignment, STBM), cause force to be distributed irregularly on the sealing lip (fig 1). This means that one section of the sealing lip will be subjected to more force, causing an enlargement of the contact area between lip and counterface surface, whereas the opposite section will be correspondingly unloaded and its sealing effect reduced. Guideline values for the permissible coaxiality deviations for SKF seals can be obtained from the diagram 1.

subset: commoncrawl


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This forum is for introduction of members and a place where Members can get to know more about each other
Use this control to limit the display of threads to those newer than the specified time frame.
Allows you to choose the data by which the thread list will be sorted.
Order threads in...
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Commencement 2013 Webcast
POSTED ON: May 28, 2013
Happy students and proud families and friends gathered in the Great Hall on May 29th to honor the 2013 graduating class of The Cooper Union for the Advancement of Science and Art at the154th commencement. You can view the entire event below. Highlights include the Student Address by School of Art graduate James Allister Sprang (00:48) and the Commencement Address by The Honorable Michael R. Bloomberg, Mayor of the City of New York (01:12).


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The conceptual framework is aligned with the 2012 Framework for K-12 Science Education and the Next Generation Science Standards (NGSS). In the concepts below, conceptual alignment is indicated by a code that follows each aligned concept. For example, LS4.A indicates correspondence to the Life Sciences core idea "Evidence of common ancestry and diversity" from both the NGSS and the Framework for grades 3-5, P3 indicates correspondence to "Planning and carrying out investigations," the third of eight Science and Engineering Practices listed in those documents, and NOS2 indicates correspondence to the second concept outlined in NGSS's appendix on the nature of science, "Scientific knowledge is based on empirical evidence." Read more about Understanding Evolution and the NGSS/Framework alignment.
The Understanding Evolution Framework is divided into five strands, and a selection of teaching resources (i.e., lessons, activities, readers, and interactive online modules) targeting most concepts has been identified.
Jump to: History of Life | Evidence of Evolution | Mechanisms of Evolution | Nature of Science | Studying Evolution
Conceptual framework
Teaching resource database
Image library
Dealing with objections to evolution
Correcting misconceptions
Alignment with science standards
Suggest a lesson or resource for Understanding Evolution
Read how others have recognized the Understanding Evolution website.


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San Antonio Water System (SAWS) has taken a major step forward to secure one of the largest non-Edwards supplies in its history. On July 13, the Gonzales County Underground Water Conservation District (GCUWCD) approved permits for SAWS to produce and transport up to 11,687 acre-feet of Carrizo Aquifer water from Gonzales County.
In 2006, SAWS applied for permits from GCUWCD to produce Carrizo Aquifer water in Gonzales County, but the permit was formally contested by several parties. Since that time, SAWS has worked cooperatively with its regional neighbors to reach settlement agreements with most of those parties to drop their opposition, including the Schertz-Seguin Local Government Corporation, Canyon Regional Water Authority, Gonzales County Water Supply Corporation, and the City of Nixon.
"Throughout this project, we've worked closely with our Gonzales neighbors and other regional partners to come to an agreement that can truly benefit all of our communities," said Robert R. Puente, SAWS president/chief executive officer. "These permit decisions are never easy, so we very much appreciate the hard and diligent work of the Gonzales County Underground Water Conservation District over the last several years."
SAWS also continues to work with the Schertz-Seguin Local Government Corporation on a partnership to use the Corporation's infrastructure to transport water from Gonzales County to San Antonio. Instead of building a new pipeline, SAWS would "rent" available capacity in an existing pipeline owned and operated by Schertz-Seguin Local Government Corporation.
"SAWS has offered to become a paying customer of our system, helping our community pay its infrastructure debt and keep our water rates low. It's a win-win partnership," said Schertz City Manager Don Taylor.
In addition to the water produced with its GCUWCD permits, SAWS has discussed the potential purchase of water that is surplus to the current needs of its regional neighbors – investing in neighboring communities by becoming a paying customer of regional utilities. Up to 5,550 acre-feet of additional supply could be added to the total project as a result of potential agreements, for a total supply to San Antonio of up to 17,237 acre-feet per year.
The SAWS Regional Carrizo Aquifer Project is estimated to cost $131 million, with water for approximately 40,000 households expected to start flowing to San Antonio in late 2013.


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because sometimes a pocket knife is not enough
Are you interested in the logo? We have it available in large versions so please if you use it head over to the logo page for the logo and the usage guidelines.
Flask is a microframework for Python based on Werkzeug, Jinja 2 and good intentions. And before you ask: It's BSD licensed!
Latest Version: 0.12.2
from flask import Flask
app = Flask(__name__)
def hello():
return "Hello World!"
$ pip install Flask $ FLASK_APP=hello.py flask run * Running on http://localhost:5000/
If you are looking for some example code of applications written with Flask, have a look at the sources of the examples on github:
Found a bug? Have a good idea for improving Flask? Head over to Flask's github page and create a new ticket or fork. If you just want to chat with fellow developers, visit the IRC channel or join the mailinglist. You can also directly add issues and feature requests to the issue tracker.


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Reinsdorf confirmed that Williams has the power to fire Guillen but never asked for his approval. … Reinsdorf explained why Williams has the authority to make chances as he sees fit, although Williams said Tuesday he has no intention of making chances during the Sox's winning trend in the past 10 days.
"The biggest mistake I ever made, but I would make it again, is I let Hawk (Harrelson) fire Tony La Russa," Reinsdorf said. "I would hope Kenny would never come to that conclusion. But you can't make a general manager have a manager he doesn't want. You can't make a manager have a coach he doesn't want. I can't make the head of the accounting department work with someone he doesn't want. I hate to think about it and I don't think it will ever come to it and Kenny says he doesn't see it, but that's the way it works."
Reinsdorf, also, said the Sox have the resources to add a player if they're in the playoff hunt, and acknowledged that the Sox are playing better but they are playing a soft part of the schedule too.


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Monday, February 04, 2013
Sports News
Greer signs letter of intent with Indiana Wesleyan
Send a link to a friend
[February 04, 2013]
Friday afternoon, Lincoln High
School senior Marissa Greer signed her letter of intent to play
softball for Indiana Wesleyan University in Marion, Ind. Marissa is
the daughter of Jim and Janice Greer of Lincoln.
Greer's softball career at
LCHS has been filled with accomplishments that made her an
attractive candidate for Wesleyan coach Steve Babinski.
Babinski states: ''Marissa is a proven leader on and off the
field. She has demonstrated the ability to manage her time and
accomplish excellence in the classroom, a heart for serving others,
and success on the field. She is the kind of kid every coach would
love to call their player, and I am truly excited to help her
develop spirituality, physically and mentally. Marissa is a great
fit for my coaching style, and I am thrilled to see her in a Wildcat
uniform next year."
In her high school career Greer has been a two-time member of the
all-star team in the Central State Eight and has twice been named
Most Valuable Pitcher in an all-star game. Her sophomore year she
was named the LCHS Offensive Player of the Year. Twice in her career
she was been named the LCHS Most Valuable Player of the Year. Her
junior year she had a .330 batting average, .435 slugging average,
12 doubles, 23 RBIs, 184.2 innings pitched, 182 strikeouts and 16
[to top of second column]
Greer has also done well in her academic career at LCHS,
maintaining a 4.129 GPA and ranked seventh of 191 in her class.
She is a three-time member of the Academic All-Conference, a
member and tutor chair of the National Honor Society, a member
of the National Honor Society of High School Scholars, a student
government member all four years, and a member of the Spanish
Club, LEAF Club and Art Club.
She is also active at Lincoln Christian Church and involved with
the church youth group.
The first of Greer's college criteria will actually be realized
this summer. After graduating from LCHS in May, Greer will be
included in an IWU mission trip in July to Auckland, New Zealand.
The mission troop will consist of a variety of members of the IWU
athletics programs. They will partner with the Wesleyan Methodist
Church of New Zealand in reaching out to youth there through
athletic activities.
In addition to softball and missions, Greer plans to focus on the
pre-med program at the university, with ambitions to become a
doctor. Friday afternoon she said she has not yet decided if she
will pursue a specific medical specialty.
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John Connolly is the bestselling author of Nocturnes - a collection of macabre short stories, and the Charlie Parker novels that have successfully blended mystery with the supernatural. Over five books - beginning with Every Dead Thing - Connolly's main character, private eye Charlie Parker, has found himself in some pretty sticky situations. In Connolly's latest, The Black Angel, the character even visits the Czech Republic to learn more about the origins of a famous bone chapel. The author, who is Irish, spent a great deal of time in this country,
In today's special programme we meet Joyce Pritchard, an American woman who recently went back to her roots, when she visited the isolated Czech villages in Romania from which her great-grandparents emigrated a century ago. She and 14 other Americans of Czech-Romanian descent met long-lost relatives and experienced old Czech customs in a region somewhat left behind by the modern world. It was, says Joyce Pritchard, the trip of a lifetime.
One of the world's most famous film directors, Roman Polanski, was in Prague this weekend to attend the premiere of his latest movie Oliver Twist, an adaptation of Charles Dickens' classic novel of life on the streets of Victorian London. Oliver Twist is the latest major movie to be filmed in Prague, mostly at the city's Barrandov studios. So is it any good? Theo Schwinke, editorial director of Monitor CE, publishers of the Prague Daily Monitor, was at the premiere.
"Something Like Happiness", a new film by Czech director Bohdan Slama, won its first major success on the international stage at the weekend, clinching the Best Film award at the prestigious San Sebastian film festival. To add to the film's success, Ana Geislerova won Best Actress for her portrayal of a woman suffering from severe mental problems in the film, about ordinary people trying to survive the trials and tribulations of life. Tomas Baldynsky is a film critic for the magazine Reflex.
Prima ballerina Daria Klimentova is undoubtedly one of the most popular Czech dancers ever, with an impressive career in the Prague National Theatre Ballet, the Cape Ballet Company in Cape Town, the Scottish Ballet in Glasgow, and since 1996 the English National Ballet. On Tuesday, an exhibition of 60 photographs opened to the public in the foyer of the Albert Hall that depicts her career both on and off stage.
Many of you are probably familiar with the Eurovision Song Contest, an annual contest in which European countries compete for the best pop song. It has been taking place since 1956, and hundreds of millions of people all around the world now tune into it each year. But those hundreds of millions do not include the Czechs.
The "Salvage of Cultural Heritage" is a project whose main objective is to seek and preserve significant works by our famous predecessors which are important for our time as well as for future generations. The project includes some of the original scores by great Czech composers from the 19th century, but also the renovation of other cultural sites, such as Charles Bridge in Prague, the Baroque theatre in Cesky Krumlov or the house where Gustav Mahler was born at Kaliste near Humpolec.


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Markakis underappreciated, but not by Orioles
Right fielder shows up every day with little fanfare, performs at high level
BALTIMORE -- Consistency is one of the most prized assets in a baseball player. Don't get too high, don't get too low. Dependability. It's one of the bedrock values of the game.
Paradoxically, though, sometimes players who simply show up every day and perform their job at a high level and don't make waves can soon be taken for granted. Players, for example, like Orioles right fielder Nick Markakis.
He's the team's longest-tenured player. He's played in every game this season. His single in the first inning of Monday's night's 4-0 win over the Red Sox at Camden Yards extended his hitting streak to 14 games; earlier this season he hit in 18 straight.
His two-run homer off Boston starter Jake Peavy in the fifth gave the O's some breathing room as they went on to win for the sixth time in their last nine games.
But he's never made the All-Star team and has been overshadowed on his own team by the prodigious power of Nelson Cruz, by 2012 and '13 All-Star Adam Jones, by the eye-catching skills of third baseman Manny Machado and even by the concern over the elbow problems that have landed catcher Matt Wieters on the disabled list.
Buck Showalter, of course, is keenly appreciative of everything his leadoff hitter adds to the mix.
"We're lucky to have him," the manager said Monday night. "Nickie's just a consistent human being. You look at him as a husband and a father and a teammate and an Oriole, and it's not surprising to anybody that he's a consistent player. He doesn't have that roller coaster of emotions but, believe me, there's a real fire burning inside him. And most of that has to do with wanting the Orioles to win."
Markakis has six homers this season. His career high is 23, so Showalter was asked if he sees signs that his power is starting to come around. The manager shrugged.
"It's the consistency thing," Showalter said. "Nick will take what they give him. He's real hard to play in the era of all the shifts and everything that's going on. Where do you play him? It's hard because you're always trying to find an advantage," he said.
"But there's not just one way to pitch him. You can't stay in all the time. You can't stay away. You can't go up. You can't stay breaking ball all the time. He goes through some periods like all of us, but you always feel like with him tomorrow is the day he'll start all over again."
Which reminded Showalter of a story from his days managing the D-backs. An amazing story, really, because to illustrate how difficult Markakis is to defend, Showalter brought up Hall of Famer Tony Gwynn.
"We gave up and told everybody that this guy makes a living hitting balls where people don't play as consistently as anybody who's ever played," Showalter said. "So I said that I wanted everybody to play where they've never played before. I said, 'Let's just try something else.' We put the third baseman out of position. We put the shortstop out of position. We put the outfielders out of position. Because, the way it was going, he was hitting .420 at the time. So why would you play conventional?
"It worked for one night. And the next night he got four hits."
Showalter obviously isn't suggesting that Markakis is as good as Gwynn. But one measure of his importance to the Orioles is this: In the team's 32 wins, he's hitting .352 with an .897 OPS. In the 30 losses: .264 and .689.
Markakis, naturally, discussed his impressive performance with the same emotion he might have had talking about what he'd had for lunch.
"I'm feeling good up there, but the outcome ain't going to be there sometimes," he said. "I'm seeing the ball well, putting good swings on it. I'm going to try not to change anything. Stick with the same approach. Stick with what's working. You can look back and say it's a bunch of stuff. The main thing is staying healthy. If you stay healthy and strong, especially in this game, which is such a long season, it can carry you a long ways."
He's not about to pop champagne over his hitting streak, either, even though he and Toronto's Jose Bautista are the only players in the Major Leagues with two hitting streaks of at least 12 games.
"I don't look too much into it," he said. "My job in the leadoff spot is to get on base, especially with what I've got hitting behind me. As the leadoff guy, you're looking to get on base any way you can. Walk, hit, hit by pitch, error. As long as you get on you feel like you're doing your job."
He's done his job long enough and consistently enough to have moved into the Top 10 in Orioles history in several offensive categories including hits, doubles, extra base hits, RBI and walks.
He's done it quietly, so his contributions may be underrated. But not in Baltimore's clubhouse.


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From birthdays to housewarmings, plants are a gift that keeps on giving. 1-800-FLOWERS.COM® offers a variety of plant gifts like flowering, house, bonsai and orchid plants that will add cheer and life to any room.
In a basket, decorative planter, or seasonal container, flowering plants infuse vibrant color and life into any room. From hydrangeas to gardenias to roses, a flowering plant delivery can be the perfect long-lasting birthday, anniversary, thank you, or get-well gift.
Topiaries, floor plants and potted plants serve as a constant reminder of your sincere expression. House plants are an amazing choice of plant gift for almost any occasion that will bring joy along with smiles to their precious faces.
The bonsai offers a rich history along with a unique natural artistic expression. The gift of a bonsai plant is one of generosity and a thoughtful expression during birthdays and other memorable holidays.
The many shades and natural designs of orchids can serve as an elegant expression of your admiration. Learning how to care for a gorgeous orchid is an adventure your someone special will appreciate and enjoy.
When it's time to send the very best in plants, look to 1-800-FLOWERS.COM® for guidance and quality flowering, house, bonsai, and orchid plants. Send a same-day plant delivery they will cherish in their home and in their hearts today.


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Robin Williams' wife: He had Parkinson's disease
Los Angeles — Robin Williams was in the early stages of Parkinson's disease and was sober at the time of his suicide, his wife said Thursday.
In a statement, Susan Schneider said that Williams, 63, was struggling with depression, anxiety and the Parkinson's diagnosis when he was found dead Monday in his Northern California home.
Schneider did not offer details on when the actor comedian had been diagnosed or his symptoms.
Williams' death shocked fans and friends alike, despite his candor about decades of struggle with substance abuse and mental health. With Parkinson's, Williams faced shouldering yet another challenge.
Parkinson's disease is an incurable nervous system disorder that involves a loss of brain cells controlling movement. Tremors, sometimes starting out in just one hand, are among the early symptoms.
It can also cause rigid, halting walking, slowed speech and sometimes dementia. Symptoms worsen over time and can often be treated with drugs.
Actor Michael J. Fox, who has long had the disease, is known for his efforts to fund research into it. Pop star Linda Ronstadt revealed in 2013 that she had Parkinson's and said the disease had robbed her of her ability to sing. Boxer Muhammad Ali, the late radio personality Casey Kasem and the late Pope John Paul II are among other well-known figures diagnosed with the disease.
"Robin's sobriety was intact and he was brave as he struggled with his own battles of depression, anxiety as well as early stages of Parkinson's disease, which he was not yet ready to share publicly," Schneider said.
Parkinson's affects about 1 million people nationwide, 6 million globally. The cause isn't known but genes are thought to play a role.
There is no standard test for Parkinson's; doctors rely on symptoms, medical history and neurological exams to make the diagnosis.
Dr. Tanya Simuni, director of the Parkinson's Disease and Movement Disorders Center at Northwestern University's medical school in Chicago, said patients often react to the diagnosis with surprise and despair.
Depression is often present even in early stages and can sometimes precede tremors that help doctors make the diagnosis, Simuni said.
Referring to Williams, she said it's important to emphasize that not everyone who is depressed is at risk for Parkinson's, "especially in this tragic case."
She noted that many can live for years without severely debilitating symptoms, but also that 20 years after diagnosis, as many as 80 percent develop dementia.
Williams had publicly acknowledged periodic struggles with substance abuse, including alcohol. Recently, depression prompted him to enter rehab.
Schneider said that those who loved Williams are taking solace in the outpouring of affection and admiration for him.
"It is our hope in the wake of Robin's tragic passing, that others will find the strength to seek the care and support they need to treat whatever battles they are facing so they may feel less afraid," she said in her statement.
Williams, whose comic brilliance first gained wide attention on the 1980s sitcom "Mork & Mindy," evolved into a respected dramatic actor who starred in films such as "Good Will Hunting," for which he an Oscar, "Dead Poets Society" and "Mrs. Doubtfire."
He was invariably upbeat in public and with his friends and colleagues, and was known for his philanthropic efforts and support for U.S. troops and veterans.
Copyright 2014 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


text:
Apply Now View All Jobs by this Recruiter
Job Description
Key Skills
Transportation / Logistic / Shipping / Marine
Functional Area
Cargo / Freight / Transportation / Packaging / Shipping
Number of Vacancy
Higher Secondary, Secondary School, Vocational Course, Diploma, Advanced/Higher Diploma, Professional Degree, Other Bachelor Degree
About Sardius Technologies
Sardius Technologies established in 2012 is one of the most successful Authorized International Student Recruiter in Chennai, Tamilnadu. Our consultancy has been serving for six years in abroad services. We have helped more than 350+ students every year to pursue paid abroad internship in various countries. We are one of the most trusted name in the abroad education industry. We offer free consultation on opportunities for various industries, human resource and training needs. Sardius Technologies guides students in achieving their international professional career through abroad Internship program. Our capabilities span both the technology and knowledge in various domains & has impacted over 350+ learners since inception. Deliver competitive, outstanding service to our customers trust with assure delivery of services on time. rnrn Our vision is to become the recognized industry leader in learning services and achieve the goal as a team. Our mission is to uphold the student's in achieving their career goal with satisfaction and confidence through distinctive quality and unparalleled services. More of the countries have been added to our list of services. rnrnWe have successfully entered into our sixth year of our service Fly Abroad with Internship.
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Watchuseek Blog
Wednesday, October 3, 2012
Setting sail: Thomas Mercer LE Marine Chronometer 'Classis'
We reported on the revival of Thomas Mercer, the renowned British marine chronometer firm in August. Now the Thomas Mercer Chronometer, known as Classis, and designed by one of Britain's leading design firms, Andrew Winch Designs, has been officially launched at Monaco Yacht Show.
Main features of the timepiece
The name 'Classis', from the Latin word for fleet, heralds the next dynasty of chronometers from Thomas Mercer.
Produced in a limited series of 10 units and inspired by the shape of a winch, the chronometer recounts the most important voyages of discovery in the history of navigation.
Each facade of the timepiece pays homage to famous ships that played a leading role in the world's destiny. The departure year, the coordinates of the most significant points reached during the trip and the image of each ship are engraved on the case, and the twelve names are made of satinwood inlaid on a fine ebony Macassar body. In addition to this, the dozen achievements are symbolically united in the Mercator Map standing out from the dial.
The style and beauty of the exterior of Classis is also found in the mechanism. The escapement, the beating heart of the mechanism, comes in its Spring Detente form, and is visible on the dial.
The movement is in a stunning bi-colour finish: a beautiful combination of polished and grené effects. Features include an 8-day power reserve, and a chain and fusee and spring detente escapement mounted on the quintessential gimballed suspension.
The design, while featuring the traditional elements of a pure chronometer, has been transformed into a work of art.
The Thomas Mercer Marine Chronometer 'Classis'
Thomas Mercer: How the legend began
Thomas Mercer enjoys an illustrious history, but it very nearly never got off the ground. 1854 Having decided that the English watch and clock industry held no future for him, Mercer, 32 years old at the time, took a coach to London and bought himself a one-way ticket to America. While awaiting passage, he saw a marine chronometer in the shop window of John Fletcher, one of the most important chronometer makers of the day. He walked in and asked for work, and was accepted as a watch springer and finisher.
During this period, the Greenwich premium trials were being held, to enable the Royal Navy to find makers capable of supplying and servicing chronometers that could be relied on to perform accurately and consistently under the extremes of temperature and motion encountered at sea. High prices were paid for chronometers that passed these trials. Two years later, Mercer left Fletcher's service to set up on his own as a chronometer maker at New North Road, London.
Mercer became involved in the British Horological Institute, in 1874 he set up a factory behind his house at 14–15 Prospect Road St Albans. Thomas Mercer marine chronometers are revered in British maritime history and are most famously linked to Shackleton's trans-Antarctic expedition (1914-1916), better known as the 'Endurance Expedition'.
The expedition was ultimately unsuccessful after Shackleton's ship, Endurance, became trapped in the ice and was destroyed. All of the men survived their ordeal of spending 22 months in the Antarctic however, after
Shackleton managed to lead his crew to safety – using his Thomas Mercer chronometer (now on permanent display at the National Maritime Museum in Greenwich) during the open boat trip on the James Caird.
Thomas Mercer played an active role in the restoration of H1 and H3; the clocks that John Harrison invented in the 18th century to win the Longitude Prize and that can be considered as the ancestors of the modern marine chronometer. Both clocks are now exhibited at the Royal Observatory in Greenwich.
The importance of the Mercer family to the British Admiralty was illustrated during WWI, when Thomas' son, Frank, returned from duty in Egypt to lead the chronometer industry, at the request of the Admiralty.
About Andrew Winch Designs
Andrew Winch Designs is an award-winning British based design studio, founded in 1986 by the designer Andrew Winch. Their diverse portfolio encompasses yachts, aviation and architecture, each of their projects is entirely unique, reflecting the client's tastes and lifestyle. What underpins all of their work is quality, attention to detail and the enthusiasm of their team. Working with the leading shipyards and completion centres all over the world, Andrew Winch Designs are recognised internationally for their exquisite designs.
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(89) Customer Reviews
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The new Dueler A/T Revo 2 features semi stealth tread blocks to promote higher tread stiffness and improved handling while enhancing water evacuation. It has a stepped inside notch and saw tooth groove to aid in snow traction, as well as an open shoulder tread design to help evacuate water. The P-Metric sizes also have dual layer tread and NanoPro-Tech which are rubber treatments which contribute to optimal traction as the tire wears.
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So happy these Bridgestone are off of my truck. They had a suicidal tendancy to wander into oncoming traffic, or into the ditch, since they were new. Sitting overnight would flatspot them as well. The Pirellis I replaced them with track straight and true. I would not recommend these tires at all.
Size: 265/70R17
Vehicle: 2005 GMC Sierra 1500 4 Dr Extended Cab Pickup, 6 Ft Bed SLE (265/70R17 113 S) with 70000 KM of Tire Wear
made this review on 4/4/2018 and is a
Confident, Experienced Driver
made this review on 11/11/2017 and is a
Confident, Experienced Driver
I've had several sets of these tires and always get 80k- 100k out them when I replace them and still have useable tread for summer but not suitable for snow removal(my truck has over 500k now), I first had the Michelin ltx's on my truck when I bought it and would get stuck on wet grass and when plowing snow with the truck I always had to have it in 4wd. After buying these I could plow in 2wd unless it was a 6" snowfall or more then I'd have to turn on the 4wd. I don't find them the least bit noisy like some of the other reviewers. Long tread life, and great traction in all conditions.
Size: 285/75R16
Vehicle: 2006 Ford F-350 Super Duty 4 Dr Crew Cab Pickup, 8 Ft Bed Harley-Davidson Edition SRW 20" option with 80000 KM of Tire Wear
made this review on 7/31/2017 and is a
Confident, Experienced Driver
This tire should have been labeled 'all season' instead of 'all terrain". It is a highway only tire. No traction in wet and snow or slippery conditions. Got really noisy after 20000 miles.
made this review on 6/28/2017 and is a
Confident, Experienced Driver
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A Carlsbad woman charged with stealing more than $170,000 from the Oceanside Elks Lodge has also been charged with stealing about $70,000 from her elderly mother, apparently to feed a gambling habit, according to prosecutors.
Morri Lee Kelsey, 57, was jailed in February on charges of forging checks to steal from her mother, with whom she shared a home, prosecutors said.
The thefts involving her mother came after Kelsey was arrested for stealing from the Elks Lodge 1561, where she worked as the bookkeeper.
Kelsey failed to appear for an arraignment hearing in July 2012 but appeared at a subsequent hearing and was allowed to remain free without posting a bond, Deputy District Attorney Bruce Silva said Monday.
"I had no idea she was out there committing more crimes," Silva said. He said the thefts from Kelsey's mother weren't discovered until December when Kelsey's mother went to Carlsbad police.
Kelsey is accused of using forged checks to take about $70,000 from her mother from July through December last year, Silva said.
She is being held at Las Colinas Detention Facility in lieu of $150,000 bail pending an April 6 preliminary hearing, Silva said.
Kelsey faces multiple felony charges including forgery, identity theft, grand theft and theft from an elder or dependent adult.
She was the bookkeeper at the Elks Lodge for about seven years before her arrest, said Andy Korbacher, a lodge trustee and special adviser to the lodge.
He said he was reluctant to talk in detail about Kelsey because of the pending case against her, but that she had been a trusted worker and the charges were "a complete shock."
Korbacher said the Elks discovered the theft in February 2012 when they started to take a closer look at their books.
According to prosecutors, Kelsey about $170,000 from the Elks Lodge between 2009 and 2012.
Silva said that money and thefts from her mother seem to have gone to pay for gambling.
"It appears that that's what she was probably doing with the money," Silva said.
The Benevolent and Protective Order of Elks is a nationwide social club that places an emphasis on faith and patriotism.
Members conduct rituals and commit themselves to community service, according to the Elks website.
Members must be U.S. citizens, at least 21 years old, believers in God and of good moral character, the site says.
Korbacher said the theft put a crimp in the lodge's charitable activities.
"That's where she took it," Korbacher said. "It's been very hard to recover. We've been working very hard at it."
Because of what happened with Kelsey, Korbacher said the Elks Lodge has adopted new security procedures.
"We've added basically a checks and balance system where two people sign checks and oversee the bookkeeping," Korbacher said.
SEE Theft • page 3


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What does Shirley Plantation have to offer that no other attraction can offer? Shirley Plantation is the most authentic and intact colonial attraction in America and has been continuously owned and operated by eleven generations of the same family since 1638. Shirley Plantation is Virginia's first plantation (1613), America's oldest family-owned business and farm (1638), and one of the first economic engines of the New World.
The guided tour of the Great House showcases almost 400 years of family stories as well as original family furniture, portraits, silver, and hand-carved woodwork. Also included with admissions are gardens and eight original colonial outbuildings surrounded by open fields and the expansive James River.
Today, Shirley continues as a working plantation, a private family home, a growing business, a National Historic Landmark, and an unbroken link between the past and the present.
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Price Information
- $12.50 for Adults. $8.00 for Youth (7-16). Discounts available for AAA, Seniors, and Military.
Last Updated: 10/10/2017


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This gorgeous hand dyed yarn is Dyed to Order on our 80/20 Rock n' Roll sock base and sold as a single 100 gram hank or as a small batch. The beautiful tones will work up into a unique pair of socks, shawl or even a beautiul sweater.
Our yarns are all unique and may have small variations from skein to skein. I recommend alternating skeins every few rows in projects using multiple skeins.
Although Superwash yarn is machine washable, I recommend hand washing in cold water and drying flat to best care for your finished project.
This yarn is dyed with professional acid dyes and gently washed. However, some color bleeding may still occur for the first few washes. Some colors are more prone to bleeding than others.
We have done our best to capture the colors as accurately as possible. Please keep in mind that colors may vary from monitor to monitor.
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Skillet sets fire to Denver
Guitarists Korey Cooper, left, and Ben Kascia get the party started Friday night at the Paramount Theatre. Photos by Eliza Marie Somers
Skillet continued its assault on "Panheads" at the sold-out Paramount Theatre on Saturday night. It should be illegal the way the band elicits whiplash and laryngitis. Something frontman John Cooper truly enjoys — even more reason for all-points bulletin.
The hard rock Christian band went over the top during its Denver stop of its latest "Awake and Alive" tour that also featured Canadian pop band Hawk Nelson, metal rockers Decyper Down and newcomers The Letter Black.
Opening their set on hydraulic lifts, guitarists Ben Kasica and Korey Cooper got the crowd roiled up while being raised to the rafters and belting out their hit "Comatose."


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Brooke Mueller Picks Up Where Ex Charlie Sheen Left Off with Drugs and Assault
Charlie Sheen hasn't been in the tabloids much lately, but it seems his most recent ex-wife Brooke Mueller is picking up the slack.
Mueller, 34, was arrested in Aspen, Colorado on Friday night after another woman reported the erstwhile Mrs. Sheen assaulted her at a nightclub.
When police caught up with Mueller at another club and arrested her for the attack, they discovered she had enough cocaine on her person to also levy a charge of possession with intent to distribute -- a class four felony.
She posted bond of $11,000 and is due back in court on December 19.
Mueller is no stranger to drug problems. She's done multiple stints in rehab, and during her divorce from Sheen, both sides claimed the other was an unfit parent due to substance abuse.


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Strictly PhD dancingPosted: December 18, 2010 Filed under: Uncategorized | Tags: dance your phd, galaxies, strictly come dancing 1 Comment
[tweetmeme only_single=false service=wp.me source=allinthegutter]
It's the grand final of Strictly Come Dancing in the UK tonight. If you're not aware of this series it pairs professional dancers with celebrities and then they compete over many weeks to see who's the best dancer (if you're in the USA it's the same as Dancing With the Stars). Since our travel plans were foiled by the snow this morning, my mum and I will be settling down (probably with a Christmas glass of sherry) to watch it at home instead (I think we'll be voting for Matt if you care about that sort of thing).
It's not just celebrities that get to take part in stuff like this though. Since 2008 scientists have had the chance to explain their research through the medium of dance in the annual `Dance your PhD' contest. One of my fellow postdocs in Nottingham, Ruth, took part in the very first competition, presenting her thesis work on "The eventful life of galaxies in low-density environments". Here she is as a small galaxy tangoing around, and eventually merging with, a much bigger companion:
I doubt any of the Strictly competitors tonight will be thinking much about expressing science in their routines (though if they did maybe they'd need a peer review panel of judges of as well) but it's nice that someone out there is!
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EERC news
May 27, 2016
The 40th Anniversary Research Workshop was held in Kyiv School of Economics, Kyiv May 21 - 22, 2016.
December 15, 2015
Your idea could be the next winner of the Global Development Awards Competition 2016. Every year, GDN awards up to $US 90,000 worth of grants to research proposals and innovative development projects as part of the Global Development Awards Competition. The deadline for submitting the proposals is 15 January, 2016.
December 02, 2015
Cеминар будет проводиться в КШЕ в Киеве 117-18 декабря 2015 года.
The Kyiv School of Economics invites students for the Autumn 2015 intake of KSE Master in Business Administration Program.
August 05, 2015
The unique KSE MBA program efficiently combines a comprehensive approach to a real-life case learning, analytical methods for decision-making and is specifically designed to educate a new generation of business leaders on how to make the most out of opportunities the global markets offer. KSE MBA combines high academic standards of top EU and US business schools with practical real-life cases from top employers of Ukraine which constitute an essential part of the program curriculum.
The 40th Anniversary Research Workshop
May 27, 2016
The 40th Anniversary Research Workshop was held in Kyiv School of Economics, Kyiv May 21 - 22, 2016. It consisited of two days. In addition to a usual EERC workshop, on the first day May 21st there was one day of presentations from both former participants and EERC experts. The day of presentations by past EERC participants and EERC experts was open to the public. On May 22nd there were presentations of final reports.


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Toy giant Hasbro, for reasons known only to Hasbro, do not like the fact that Aussie Martyn Yang runs a blog about Nerf Guns. What they're doing about it will make you wonder what's come of this world.
Yang's blog, Urban Taggers, exists to showcase Nerf Guns. People post images of guns they've bought, they talk about the toy weapons. It's a fan site.A comprehensive one, which catalogues all kinds of Nerf Guns, posts videos of them in action, and even has reviews of them.
Anyway, last month, Yang was contacted by Hasbro's public relations team, who were offering to send his site some swag for a giveaway. So he replied, and gave the company his postal address. The swag never came. What did come was a letter from Hasbro's law firm, Baker & McKenzie, demanding that Urban Taggers not only remove images and information about an unreleased and upcoming Nerf Gun, but give up the identity of the user who supplied the information.
After telling them he got a lot of his information off the internet and Chinese auction sites, and that maybe Hasbro should try that sometimes, Yang then came home one Sunday afternoon to find two people - a "strange woman and a big-looking repo-man-looking guy" - had been lurking outside his apartment all day, wanted to interview him and record the conversation.
A reminder: this is over images and user reviews of plastic toy guns Yang bought off a Chinese website.
The matter has now been reported to the Office of the NSW Legal Services Commissioner, and Yang is "seeking redress" from the law firm for their conduct.
To read all the emails sent between Yang, Hasbro and the law firm, check out Crikey's great piece on the story below.
UPDATE - Hasbro has issued the following statement:
We appreciate the opportunity to provide the following statement concerning Hasbro's investigation into "leaked" IP information regarding its NERF brand products. As with anything, there are two sides to every story. While we cannot comment on the details of any ongoing investigation, Hasbro takes all circumstances of its stolen and leaked IP very seriously and will continue to investigate sources of unauthorized information and products as it relates to its brands. We would like to clarify one of the inaccuracies that has been reported. While a local Hasbro Australia marketing team did reach out to the Urban Taggers website to engage in promotional activity for which it required its address, it was completely unrelated to the confidential global investigation being conducted on Hasbro's behalf by independent investigators looking into sources of leaked IP information. Hasbro greatly values and appreciates its fan communities and is very proud of its strong relationships with many bloggers and sites that cover our brands and products.
Nerf guns at 10 paces: Hasbro faces boycott after siccing lawyers onto fan site [Crikey]


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Walking Stick (Stick Bug) Costume
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Stick Bug costume
View more insect costumes created by Heather.
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This homemade costume for boys entered our 2011 Halloween Costume Contest, and won a special prize in the Most Creative Costume nomination!
A word from Heather, the 'Walking Stick' costume creator:
I made a total of 13 costumes this year, and we stuck to an "Insect" theme.
One of the costumes was a Walking Stick, (or stick bug). I made it for my oldest son, and it was one of the hardest to make.
Unfortunately, The first one I made was out of one long 6" cardboard tube, with legs and antenna attached by drilling holes and sticking them inside the tube and zip-tying them to stay in place. The idea was sound, but the costume was too heavy, too awkward, and too long (he's on the short side and it dragged the ground. I found this out the Friday before Halloween.
The only choice I had was to start over from scratch, with lighter materials. I also remembered to measure how tall he was to make sure the second one was not too long.
Instruction Illustration Chart
I used corrugated plastic board (the kind convenience/party store use outside for advertising), and a few smaller cardboard boxes.
I cut out sections of the corrugated plastic and rolled it into a hex shape and fastened it together with zip ties. I made each section just a pit smaller so it would fit into the one before it, with about 5 sections all together. I also did this so it would curve along his back and not be so rigid.
I positioned the bug's legs just under his arms, and about the middle of the body. I used some old rubber hose to mount the legs (2 pieces, slid through the body), using the same method I used to make the body.
For the "feelers", I used the same method for making the body, but mounted them to top head part with zip ties to keep them in place. Before I started adding the body covering, I cut slits in the side of the body that would be facing his back and used some strips of black fabric to make straps. I made one set for his shoulders and one set to tie around his waist.
I used spray adhesive and started gluing on tan crepe paper (on clearance for 75 cents, got three rolls). I did three layers. Then I ripped some dark brown crepe paper (again on clearance) and glued them on with the spray adhesive to simulate bark. I also sprayed a bit of black and gray spray paint to blend it a little better.
For the eyes, I used two clears pieces from nylons packages (the 33 cent ones you find at Wal-Mart), covered them with glue and rolled them around in green glitter.
Once everything was dry (paint, glue), I sprayed on a clear coat of paint (to protect from the rain).
He really liked it, and we got a lot of compliments on the uniqueness of it.
P.S. He was supposed to be wearing his camo coat, but he didn't have it on when I took the pictures :(
Similar costumes:


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Will retirement saving soon go from opt-in to opt-out?
A recent post from ex-Boston Globe reporter Kim Blanton on the Center for Retirement Research's Squared Away blog noted that seven years after Congress encouraged employers to automatically enroll their workers in the company 401(k), "the retirement fix has run out of steam."
Blanton's blog, housed with the center at Boston College, recalled how corporate America "rushed in to adopt the feature in their 401(k) plans after the Pension Protection Act (PPA) made auto-enrollment more attractive by giving employers that used it a safe harbor from non-discrimination rules governing their benefits."
Immediately after the PPA provision became effective in December 2007, employee participation in 401(k)s increased. But since that initial bump, it's been virtually flat for years, the center claimed, and pointed to the following stats:
- In 2008, participation increased to 73% of all employees in workplaces that offered 401(k)s, up from 68% in 2007, according to Vanguard Group.
- Fast forward to 2011: participation was 74%. It has barely budged. (Last year, participation was 68%, but Vanguard said past experience indicates this figure will rise to roughly the same level when all of its clients turn in their data).
"The concept clearly works–if it's adopted," Blanton wrote. "But enough time seems to have passed that we can safely declare that the employers that were going to adopt auto enrollment already have. There's little reason to expect any great improvement in participation rates in the future."
Blanton appeared to lay the groundwork for a proposed solution she nonetheless failed to name. The post concluded with an open-ended (and curiously-timed) question: what now?
Alicia Munnell (left) was happy to answer in a piece for MarketWatch on Wednesday.
In order to make 401(k)s work better, the PPA should be changed to require all 401(k) plans to adopt annual auto-enrollment for their entire work force, Munnell, the center's director, argued.
"Auto-enrollment deferral rates should be set at a meaningful level and be accompanied by annual auto-escalation in the deferral rate," she concluded. "In other words, the time has come to make the automatic provisions mandatory components of 401(k) plans."
Retiring senator Tom Harkin, an Iowa Democrat, plans to introduce legislation in 2013 to require auto-enrollment in some form, but thus far has not done so.
Check out Alicia Munnell: Ban Actively Managed Funds From 401(k)s, IRAs on AdvisorOne.


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Image via Flick creative commons from Janet Ramsden
As well as being a tourist attraction due to its location at the south westerly most point of Great Britain, Lands End offers a diverse selection of things to see, all set in picturesque surroundings. Lands End was the location for the start of the Summer Olympics torch relay in 2012 and is also a fantastic place for walking as it boasts many breathtaking and unspoiled sea views along dramatic coastlines, cliffs, and open country.
Lands End is an area of outstanding natural beauty and it is no surprise that thousands of people every year decide to go walking and exploring there. One short yet visually stunning walk begins at Lands End and ends roughly a mile away in beautiful Sennen Cove, a settlement with a population of only 180 people and a renowned surfing resort. On this easy going walk you can expect to take in views of the ocean from staggering vertical cliff faces, stumble across the remains of an Iron Age fort (Maen Castle) and gaze across the beautiful beach of Whitesands Bay. Although the distance from Lands End to Sennen cove is only short, this walk is packed with beautiful scenery and incredible surroundings. Anyone looking for tourist information about Lands End walks can visit the Penzance tourism site.
For those who like lengthy and scenic walks, the historic town of St. Ives is a fantastic end point to a beautiful 24 mile walk from Lands End. Whilst exploring Cornwall's unspoilt beauty, walkers can enjoy many of the counties landmarks such as Pendeen Lighthouse, Whitesand Bay and even the remains of a 2nd century BC Iron Age castle at Gurnards Head. Zennor village and other hamlets dotted along this route provide stops for food and refreshments and are ideal places to rest whilst enjoying the history of this amazing county. Animal lovers should make sure to pay particular attention near Kenidjack rocks as this is a brilliant place to spot wild seals in Britain. Long walks such as this can be enjoyed over a couple of days as there are numerous hotels and B&B's along the way to cater for tourists and walkers visiting the area. For help planning or navigating a walk you could visit the Lands End tourist office.
A popular beachy walk in South West Cornwall begins at Lands End and finishes in the beautiful village of Porthcurno. A sandy beach and turquoise sea awaits walkers and tourists at the end of this route, along with the incredible Minack theatre, an open air, stone built theatre looking out over the English Channel and is one of Cornwall's most well known landmarks. On this walk you will come across incredible rock formations, most famously Enys Dodnan and the Armed Knight. This interesting and relaxing walk offers lovely sandy beaches and even a view of Longships Lighthouse, originally built in 1795. At the end of your walk a handy bus service runs hourly between Lands End and Porthcurno which provides a scenic trip back to exhausted ramblers.
If you are looking for an easy going walk along Cornwall's coastal footpaths then a trip between Lands End and St. Just might be ideal. Originally a busy mining centre, the historic village of St. Just still retains many of its original buildings and features, making it a must see for any history fanatic. Only 6 miles long, this route takes walkers across golden sands, low cliffs, through grassy meadows and offers stunning westerly views out across the sea. Passing through many idyllic areas such as Porth Nanven, Sennen Cove and Cot Valley along the way, this unchallenging walk is ideal for families and older people, while still being picturesque and full of history.
Finally, the most famous and challenging walk in Great Britain has to be the walk from Lands End to John o' Groats. Although there is no set route, many walkers enjoy the challenge of setting their own route and being able to visit hundreds of amazing places, exploring the entire country along the way. The idea of walking 'end to end' is one that attracts many avid walkers every year but with a distance of 874 miles, this isn't a walk for the faint hearted! The Long Distance Walkers Association website has information about this walk along with news and reviews from walkers who have previously completed this daunting but immensely rewarding trek. The record for completing this route on foot is held by Andi Rivett who took 9 days and 2 hours to run the entire length of Britain. If you plan to take on the challenge of walking from Lands end to John o' Groats then be warned that if you walk 22 miles a day, the route will take you 40 days so make sure to book some time off work!


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Gloria Allred had even more to say about gubernatorial candidate Meg Whitman on Tuesday.
The Hollywood lawyer held a third news conference with Whitman's former housekeeper by her side at 11 a.m.
The latest showdown with Nicky Diaz Santillan was in response to Whitman's claim that the former housekeeper was being manipulated by Allred and that she was a pawn by Democratic candidate Jerry Brown. All of those charges were denied.
If you haven't heard the story, Santillan worked for Whitman for nearly a decade as her housekeeper in Atherton. Whitman said she let Santaillan go after she said she learned she was in the country illegally. Whitman says she considered Santaillan a member of her family and was heartbroken to have to let her go.
On Tuesday Santillan rejected Whitman's family claim: "Ms. Whitman, don't say I was part of your family, because you never treated me like I was."
U.S. & World
She also said she was speaking out for herself and was not being manipulated by Allred or Brown for political gain.
Allred deflected questions about how she came to represent Santillan and whether there was any connection with the Brown campaign.
"All I can tell you is I have a client, I'm speaking out on behalf of Nicky," Allred said. "Nicky has spoken out on behalf of herself. It is insulting to Nicky to suggest that she is, in Nicky's words, anybody's puppet."
Whitman's Democratic opponent, Attorney General Jerry Brown, stayed quiet on the issue last week, but criticized Whitman for failing to help the housekeeper during a debate this weekend.
Whitman fought back by accusing Brown of orchestrating the scandal. To that Brown fired back: "Don't run for governor if you can't stand up on your own two feet and say, 'Hey I made a mistake.'" Then he turned away from the audience and faced her directly. "You have blamed her, blamed me, blamed the left, blamed the unions. But you don't take accountability.'"
Santillan has filed a claim with state regulators saying Whitman owes her $6,200 for time she worked or as reimbursement for mileage while running errands.
Whitman spokesman Andrea Jones Rivera said in a statement: "It's time for Gloria Allred to pack-up this circus and leave town." Brown's campaign did not comment on the news conference Tuesday.


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The Orioles have an afternoon game against the Toronto Blue Jays in Sarasota, and those Blue Jays aren't fooling around. They have brought some of their big guns, such as Jose Bautista, Melky Cabrera and Adam Lind. And Mark Buehrle is expected to throw three innings to start.
Here's the Jays' order: Emilio Bonifacio 4, Maicer Izturis 6, Melky Cabrera 8, Jose Bautista 9, Adam Lind DH, Mark DeRosa 5, Lars Anderson 3, Henry Blanco 2, Eugenio Velez 7, Buehrle 1.
The home team has a fairly representative lineup as well, though Nick Markakis (neck) and Adam Jones (WBC) are obviously missing.
Here's the O's lineup: Reimold DH, Roberts 4, Jackson 9, Wieters 2, Davis 3, Hardy 6, McLouth 8, Machado 5, Pearce 7.
Here's the O's pitching plan: Jason Hammel, Mike Wright, Adam Russell, Daniel McCutchen and Mark Hendrickson.
Some other notes from this morning:
I talked to Kevin Gausman about pitching against the Boston Red Sox on Saturday at JetBlue Park. I think I could classify his reaction as "excited." He asked about the park and the expected sellouts.
It's easy to forget that for some of these kids in their first go-around, spring training isn't a necessary evil but a cool experience.
Last year's top pick is expected to pitch in relief of 2011's top pick, Dylan Bundy. The Red Sox will be countering with one of their own young flame-throwers, lefty Felix Doubront.
Darren O'Day made his first appearance of the spring yesterday and said he is on a similar schedule as Jim Johnson, getting gradual work that will likely ramp up at the end. O'Day said he will definitely have at least one multiinning outing this spring.
Adam Jones, playing against the Colorado Rockies as part of USA's WBC team, was 3-for-5 with two runs, one RBI and a double.


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And now I announce my return! (crickets...)
Huh? No feast? No triumphal procession? What has happened in my absence? Well, I have been in such a long second dark age that I'll probably be barely remembered. But, nevertheless I have returned; much to the vexation of the good and proper folk of the realm.


text:
What we do
The UK Web Archive (UKWA) collects millions of websites each year, preserving them for future generations. The UKWA is a partnership of the six
Use this site to discover old or obsolete versions of UK websites, search the text of the websites and browse websites curated on different topics and themes.
Topics and Themes
Topics and Themes are groups of websites brought together on a particular theme by librarians, curators and other specialists, often working in collaboration with key organisations in the field. Find out more.


text:
Strikalite -> Lithium Batteries -> Li-Ion
We are currently having supply problems with 'Nickel Metal Hydride Batteries' (NIMH) at present due to the issues China is currently facing.
We are doing our best to supply our customers, the cells that we shall be supplying for the short term are NOT of the 'Low Self Discharge' (LSD) type. We will revert back to these as soon as they become available again.
We are having to pay premium prices for the current cells available, this may lead to temporary increased prices on our website to cover costs.
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Records 1 to 1 of 1
* Please note the labeling of goods provided may differ from that listed, specifications will remain the same
Please phone 01543 683122 for prices
©2020 On2net UK e-commerce solutions


text: From Amber White, Animal Rescue Program Aide What, to many, seemed like a cold and dreary day this weekend was an exciting day for a Kemp's ridley sea turtle; after more than nine months in rehab, he was finally ready to go home. On October 1, the last of the 11 cold-stunned Kemp's ridley sea turtles the National Aquarium Animal Rescue team took in last winter was released into the Chesapeake Bay from the quiet beach at Point Lookout State Park. Even though the air temperatures have dropped and it feels like fall, the bay water still provides optimal water temperatures for this little guy to start his new life back at sea. This turtle was kept in rehab longer than the others for continued observation of his digestive system. We always make sure we give each turtle the absolute best chance for survival in the wild. Unfortunately, in their natural environment, sea turtles come across many manmade materials that look like the food they would eat, such as plastic bags, balloons, and small plastic objects. Ingesting this trash can injure marine animals, or even result in death from asphyxiation. With his X-rays and final medical examination receiving the OK from our wonderful veterinary staff, he was given the green light for release. Neither rain nor wind could stop this turtle from making the trek across the sand and back into his natural habitat. A big thank you to the staff at Point Lookout State Park, for allowing us to use their beach for all of our releases this summer. We have a great partnership with the park staff and always look forward to working with them. Tags: animal-rescue, chesapeake-bay, cold-stunned-turtles, kemps-ridley-sea-turtles, Animal Rescue, sea-turtle, sea-turtles, turtles Categories: Animal Rescue, Animals Previous Post Next Post


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Digital customer management
B2C and B2B leaders share one focus: digital customer management
B2C and B2B leaders share one focus: digital customer management
Companies are facing unprecedented complexity. The key question for surviving in a consumer-driven world is how to make better use of digital assets to improve loyalty, accelerate eCommerce, develop sustainable growth and create disruptive business models.
Digitalization is a dominant force that has dramatically altered the relationship between customers and companies, both in B2B an B2C. It has changed the way consumers inquire, buy, react, share and even create. A disruptive digital customer experience represents an opportunity for new entrants and a challenge for incumbents.
Successful companies have a deep understanding of consumers' needs and preferences. They are able to satisfy consumers' expectations for continuous improvement and innovation, meaningful and contextualized experiences, simplicity and speed. They know not only how to create a compelling digital experience, but they also know how to disrupt their own business models, sales force, operations and CRM to prevent customer preemption by other aggregators. They are able to go beyond their own products, develop new services and get the most out of the platform economy.
BearingPoint uses a hands-on approach together with deep analysis to get a full understanding of your business challenges and help you shape your digital strategy. We combine that with our expertise in the deployment of tools and solutions for the smart usage of technology.
Digital transformation means reinventing our business model. It is a shift about how we interact with our customers, and it is also a shift in our distribution model with emergence of eCommerce. I needed a partner who was able to be very lean, quick, operational immediately, and that is what I found in BearingPoint versus other companies.
VP Global Enterprise


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Mango Father's Rights
A paternity attorney can help you determine the parentage of a child, as well as assist with child custody, support, time-sharing, and all other aspects of father's rights. Any pregnant woman or mother, any man who believes he is the father of a child, or any child who questions parentage, may bring proceedings to determine the paternity of the child in the circuit court when paternity has not already been established by law or otherwise.
Paternity cases generally are only necessary when the unmarried parents of a child can't agree on the upbringing of the child. Usually, the main culprit is time-sharing, or how much time each parent gets with the child. When this because an issue, it is not uncommon for a father to seek assistance from the courts to establish the father's legal rights. This is the only way in the State of Florida to be able to obtain legal protection of your rights and responsibilities of fatherhood. Paternity is assumed when the mother and father are legally married to each other at the time of the child's birth. Without seeking the support of a dedicated Mango father's rights attorney, the mother of the child is well within her rights to completely deny you any type of access or rights to your minor children.
According to Florida Statutes Section 742.12, the courts can require the child, mother, and the proposed father to participate in DNA testing to determine the likelihood that the father and child are genetically a match, and thus related.
Generally, paternity is determined in order to establish the correct parentage of the child so that his/her biological father is able to not only assume the responsibilities of fatherhood, but also enjoy the rights of being parent. A parenting plan and time-sharing schedule help to determine how the child will split his time between the parents, and child support will also be established, as you must first take responsibility for your child before you can appreciate the rights of fatherhood. Other aspects of a paternity action may include establishing a holiday time-sharing schedule, and dividing the payment of medical insurance coverage, extracurricular activities, birth-related expenses, uncovered/non-covered medical expenses, as well as placing the father on the child's birth certificate, changing the child's name, and dividing up the dependency exemption for the child.
As your Mango father's rights lawyer, we would be happy to assist you with your paternity case, or answering any questions you may have as to the issues addressed above. You deserve the right to a relationship with your children.
David Hurvitz is a highly trained and skilled attorney located in Mango, Florida. Mr. Hurvitz has worked in a variety of legal areas here in Hillsborough County, Tampa Bay, as well as other jurisdictions in the State of Florida. At the Law Office of David Hurvitz PA, we are committed to obtaining the best results for all of our clients.


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Cardiac two pore domain potassium channels (K2P) exist in organisms from Drosophila to humans, however their role in cardiac function is not known. We identified a K2P gene, CG8713 (sandman), in a Drosophila genetic screen and show that sandman is critical to cardiac function. Mice lacking an ortholog of sandman, TWIK related potassium channel (TREK-1 or Kcnk2), exhibit exaggerated pressure overload induced concentric hypertrophy and alterations in fetal gene expression, yet retain preserved systolic and diastolic cardiac function. While cardiomyocyte specific deletion of TREK-1 in response to in vivo pressure overload resulted in cardiac dysfunction, TREK-1 deletion in fibroblasts prevented deterioration in cardiac function. The absence of pressure overload induced dysfunction in TREK-1 KO mice was associated with diminished cardiac fibrosis and reduced activation of c-Jun N-terminal kinase activity (JNK) in cardiomyocytes and fibroblasts. These findings indicate a central role for cardiac fibroblast TREK-1 in the pathogenesis of pressure overload-induced cardiac dysfunction and serve as a conceptual basis for its inhibition for as a potential therapy.
Dennis M. Abraham, Teresa E. Lee, Lewis J. Watson, Lan Mao, Gurangad S. Chandok, Hong-Gang Wang, Stephan Frangakis, Geoffrey S. Pitt, Svati H. Shah, Matthew J. Wolf, Howard A. Rockman
Skeletal muscle has emerged as a critical, disease-relevant target tissue in spinal and bulbar muscular atrophy, a degenerative disorder of the neuromuscular system caused by a CAG/polyglutamine (polyQ) expansion in the androgen receptor (AR) gene. Here, we used RNA-Seq to identify pathways that are disrupted in diseased muscle using AR113Q knock-in mice. This analysis unexpectedly identified significantly diminished expression of numerous ubiquitin-proteasome pathway genes in AR113Q muscle, encoding approximately 30% of proteasome subunits and 20% of E2 ubiquitin conjugases. These changes were age-, hormone- and glutamine length-dependent and arose due to a toxic gain-of-function conferred by the mutation. Moreover, altered gene expression was associated with decreased level of the proteasome transcription factor NRF1 and its activator DDI2 and resulted in diminished proteasome activity. Ubiquitinated ADRM1 was detected in AR113Q muscle, indicating the occurrence of stalled proteasomes in mutant mice. Finally, diminished expression of Drosophila orthologues of NRF1 or ADRM1 promoted the accumulation of polyQ AR protein and increased toxicity. Collectively, these data indicate that AR113Q muscle develops progressive proteasome dysfunction that leads to the impairment of quality control and the accumulation of polyQ AR protein, key features that contribute to the age-dependent onset and progression of this disorder.
Samir R. Nath, Zhigang Yu, Theresa A. Gipson, Gregory B. Marsh, Eriko Yoshidome, Diane M. Robins, Sokol V. Todi, David E. Housman, Andrew P. Lieberman
The remarkable regeneration capability of skeletal muscle depends on coordinated proliferation and differentiation of satellite cells. The self-renewal of satellite cells is critical for long-term maintenance of muscle regeneration potential. Hypoxia profoundly affects the proliferation, differentiation, and self-renewal of cultured myoblasts. However, the physiological relevance of hypoxia and hypoxia signaling in satellite cells in vivo remains largely unknown. Here, we report that satellite cells are in an intrinsic hypoxic state in vivo and express hypoxia-inducible factor 2A (HIF2A). HIF2A promotes the stemness and long-term homeostatic maintenance of satellite cells by maintaining the quiescence, increasing the self-renewal and blocking the myogenic differentiation of satellite cells. HIF2A stabilization in satellite cells cultured under normoxia augmented their engraftment potential in regenerative muscle. Reversely, HIF2A ablation led to the depletion of satellite cells and the consequent regenerative failure in the long-term. In contrast, transient pharmacological inhibition of HIF2A accelerated muscle regeneration by increasing satellite cell proliferation and differentiation. Mechanistically, HIF2A induces the quiescence/self-renewal of satellite cells by binding the promoter of Spry1 gene and activating Spry1 expression. These findings suggest that HIF2A is a pivotal mediator of hypoxia signaling in satellite cells and may be therapeutically targeted to improve muscle regeneration.
Liwei Xie, Amelia Yin, Anna S. Nichenko, Aaron M. Beedle, Jarrod A. Call, Hang Yin
Multisystem proteinopathy (MSP) involves disturbances of stress granule (SG) dynamics and autophagic protein degradation that underlie the pathogenesis of a spectrum of degenerative diseases that affect muscle, brain, and bone. Specifically, identical mutations in the autophagic adaptor SQSTM1 can cause varied penetrance of 4 distinct phenotypes: amyotrophic lateral sclerosis (ALS), frontotemporal dementia, Paget's disease of the bone, and distal myopathy. It has been hypothesized that clinical pleiotropy relates to additional genetic determinants, but thus far, evidence has been lacking. Here, we provide evidence that a TIA1 (p.N357S) variant dictates a myodegenerative phenotype when inherited, along with a pathogenic SQSTM1 mutation. Experimentally, the TIA1-N357S variant significantly enhances liquid-liquid–phase separation in vitro and impairs SG dynamics in living cells. Depletion of SQSTM1 or the introduction of a mutant version of SQSTM1 similarly impairs SG dynamics. TIA1-N357S–persistent SGs have increased association with SQSTM1, accumulation of ubiquitin conjugates, and additional aggregated proteins. Synergistic expression of the TIA1-N357S variant and a SQSTM1-A390X mutation in myoblasts leads to impaired SG clearance and myotoxicity relative to control myoblasts. These findings demonstrate a pathogenic connection between SG homeostasis and ubiquitin-mediated autophagic degradation that drives the penetrance of an MSP phenotype.
YouJin Lee, Per Harald Jonson, Jaakko Sarparanta, Johanna Palmio, Mohona Sarkar, Anna Vihola, Anni Evilä, Tiina Suominen, Sini Penttilä, Marco Savarese, Mridul Johari, Marie-Christine Minot, David Hilton-Jones, Paul Maddison, Patrick Chinnery, Jens Reimann, Cornelia Kornblum, Torsten Kraya, Stephan Zierz, Carolyn Sue, Hans Goebel, Asim Azfer, Stuart H. Ralston, Peter Hackman, Robert C. Bucelli, J. Paul Taylor, Conrad C. Weihl, Bjarne Udd
Regulation of skeletal muscle development and organization is a complex process that is not fully understood. Here, we focused on amphiphysin 2 (BIN1, also known as bridging integrator-1) and dynamin 2 (DNM2), two ubiquitous proteins implicated in membrane remodeling and mutated in centronuclear myopathies (CNMs). We generated Bin1–/– Dnm2+/– mice to decipher the physiological interplay between BIN1 and DNM2. While Bin1–/– mice die perinatally from a skeletal muscle defect, Bin1–/– Dnm2+/– mice survived at least 18 months, and had normal muscle force and intracellular organization of muscle fibers, supporting BIN1 as a negative regulator of DNM2. We next characterized muscle-specific isoforms of BIN1 and DNM2. While BIN1 colocalized with and partially inhibited DNM2 activity during muscle maturation, BIN1 had no effect on the isoform of DNM2 found in adult muscle. Together, these results indicate that BIN1 and DNM2 regulate muscle development and organization, function through a common pathway, and define BIN1 as a negative regulator of DNM2 in vitro and in vivo during muscle maturation. Our data suggest that DNM2 modulation has potential as a therapeutic approach for patients with CNM and BIN1 defects. As BIN1 is implicated in cancers, arrhythmia, and late-onset Alzheimer disease, these findings may trigger research directions and therapeutic development for these common diseases.
Belinda S. Cowling, Ivana Prokic, Hichem Tasfaout, Aymen Rabai, Frédéric Humbert, Bruno Rinaldi, Anne-Sophie Nicot, Christine Kretz, Sylvie Friant, Aurélien Roux, Jocelyn Laporte
Skeletal muscle is a key organ in energy homeostasis owing to its high requirement for nutrients. Heterotrimeric G proteins converge signals from cell-surface receptors to potentiate or blunt responses against environmental changes. Here, we show that muscle-specific ablation of Gα13 in mice promotes reprogramming of myofibers to the oxidative type, with resultant increases in mitochondrial biogenesis and cellular respiration. Mechanistically, Gα13 and its downstream effector RhoA suppressed nuclear factor of activated T cells 1 (NFATc1), a chief regulator of myofiber conversion, by increasing Rho-associated kinase 2–mediated (Rock2-mediated) phosphorylation at Ser243. Ser243 phosphorylation of NFATc1 was reduced after exercise, but was higher in obese animals. Consequently, Gα13 ablation in muscles enhanced whole-body energy metabolism and increased insulin sensitivity, thus affording protection from diet-induced obesity and hepatic steatosis. Our results define Gα13 as a switch regulator of myofiber reprogramming, implying that modulations of Gα13 and its downstream effectors in skeletal muscle are a potential therapeutic approach to treating metabolic diseases.
Ja Hyun Koo, Tae Hyun Kim, Shi-Young Park, Min Sung Joo, Chang Yeob Han, Cheol Soo Choi, Sang Geon Kim
Maintenance of muscle structure and function depends on the precise organization of contractile proteins into sarcomeres and coupling of the contractile apparatus to the sarcoplasmic reticulum (SR), which serves as the reservoir for calcium required for contraction. Several members of the Kelch superfamily of proteins, which modulate protein stability as substrate-specific adaptors for ubiquitination, have been implicated in sarcomere formation. The Kelch protein Klhl31 is expressed in a muscle-specific manner under control of the transcription factor MEF2. To explore its functions in vivo, we created a mouse model of Klhl31 loss of function using the CRISPR-Cas9 system. Mice lacking Klhl31 exhibited stunted postnatal skeletal muscle growth, centronuclear myopathy, central cores, Z-disc streaming, and SR dilation. We used proteomics to identify several candidate Klhl31 substrates, including Filamin-C (FlnC). In the Klhl31-knockout mice, FlnC protein levels were highly upregulated with no change in transcription, and we further demonstrated that Klhl31 targets FlnC for ubiquitination and degradation. These findings highlight a role for Klhl31 in the maintenance of skeletal muscle structure and provide insight into the mechanisms underlying congenital myopathies.
James B. Papizan, Glynnis A. Garry, Svetlana Brezprozvannaya, John R. McAnally, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson
Glucocorticoid steroids such as prednisone are prescribed for chronic muscle conditions
such as Duchenne muscular dystrophy, where their use is associated with prolonged
ambulation. The positive effects of chronic steroid treatment in muscular dystrophy are
paradoxical because these steroids are also known to trigger muscle atrophy. Chronic
steroid use usually involves once-daily dosing, although weekly dosing in children has
been suggested for its reduced side effects on behavior. In this work, we tested steroid
dosing in mice and found that a single pulse of glucocorticoid steroids improved
sarcolemmal repair through increased expression of annexins A1 and A6, which mediate
myofiber repair. This increased expression was dependent on glucocorticoid response
elements upstream of annexins and was reinforced by the expression of forkhead box O1
(FOXO1). We compared weekly versus daily steroid treatment in mouse models of acute muscle
injury and in muscular dystrophy and determined that both regimens provided comparable
benefits in terms of annexin gene expression and muscle repair. However, daily dosing
activated atrophic pathways, including F-box protein 32 (
Mattia Quattrocelli, David Y. Barefield, James L. Warner, Andy H. Vo, Michele Hadhazy, Judy U. Earley, Alexis R. Demonbreun, Elizabeth M. McNally
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder that is characterized by extreme variability in symptoms, with females being less severely affected than males and presenting a higher proportion of asymptomatic carriers. The sex-related factors involved in the disease are not known. Here, we have utilized myoblasts isolated from FSHD patients (FSHD myoblasts) to investigate the effect of estrogens on muscle properties. Our results demonstrated that estrogens counteract the differentiation impairment of FSHD myoblasts without affecting cell proliferation or survival. Estrogen effects are mediated by estrogen receptor β (ERβ), which reduces chromatin occupancy and transcriptional activity of double homeobox 4 (DUX4), a protein whose aberrant expression has been implicated in FSHD pathogenesis. During myoblast differentiation, we observed that the levels and activity of DUX4 increased progressively and were associated with its enhanced recruitment in the nucleus. ERβ interfered with this recruitment by relocalizing DUX4 in the cytoplasm. This work identifies estrogens as a potential disease modifier that underlie sex-related differences in FSHD by protecting against myoblast differentiation impairments in this disease.
Emanuela Teveroni, Marsha Pellegrino, Sabrina Sacconi, Patrizia Calandra, Isabella Cascino, Stefano Farioli-Vecchioli, Angela Puma, Matteo Garibaldi, Roberta Morosetti, Giorgio Tasca, Enzo Ricci, Carlo Pietro Trevisan, Giuliana Galluzzi, Alfredo Pontecorvi, Marco Crescenzi, Giancarlo Deidda, Fabiola Moretti
Mutations in laminin α2-subunit (Lmα2, encoded by
Karen K. McKee, Stephanie C. Crosson, Sarina Meinen, Judith R. Reinhard, Markus A. Rüegg, Peter D. Yurchenco


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Industrial Commission
The Industrial Commission is the state agency that administers the federal Workers' Compensation Act, which provides compensation benefits for industrial injuries. The purpose of the act is not only to offer a swift and certain remedy for an injured worker, but also to ensure a limited and determinate liability for employers. The Industrial Commission was created by the North Carolina General Assembly in 1929. The governor appoints its members for six-year terms.
Additional Resources:
North Carolina Industrial Commission official website: http://www.ic.nc.gov/ (accessed October 22, 2012).
"North Carolina Workers' Compensation Law." North Carolina Industrial Commission. http://www.ic.nc.gov/ncic/pages/ncwclaw.htm (accessed October 22, 2012).
"An Act to Provide a System of Workmen's Compensation in the State of North Carolina and to Further Provide for Securing the Payment of Such Compensation." Public laws and resolutions passed by the General Assembly at its session of 1929. Raleigh [N.C.]: Mitchell Print. Co. 1929. p. 117. http://digital.ncdcr.gov/u?/p249901coll22,238612 (accessed October 22, 2012).
Image Credits:
"Letter, Accession #: H.1989.57.3." 1929. North Carolina Museum of History.
1 January 2006 | Maupin, Armistead Jones
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COVID-19 Update:
A message from our CEO. View Message
Relief from The Classy Home family.
Get special 10% OFF. Use code "SPECIAL10"
Solid Company Started in 1983, our company has been growing ever since. We are very proud that many of our employees, as well as customers, have been with us for over ten years. This high retention of employees and customers reflect the success of our partnership approach to doing business. Our strong financial condition allows us to maintain a large depth of inventory items. This means that you can feel comfortable about getting the items you want quickly from our warehouse. Besides our main office with a 400,000 square foot warehouse in Houston, TX, our distribution centers in Fontana, CA, and High Point, NC, we also maintain show spaces in Tupelo, MS, High Point, NC, Las Vegas, NV, and Long Beach, CA. Nowhere else will you find a partnership that meets the challenge of offering great quality, competitive pricing, unbeatable service and unparalleled styling. Great Quality Quality is the 1 factor. Our on-site quality control specialist checks that manufacturing meets our exact standards. This keeps our furniture at a high quality level. Unparalleled Styling Our designs promote comfort and elegance. Our research and development team is always in tune with the styles of the industry. Our customers can always depend on us for classic styling, as well as the latest styles.:
The dates below represent the closing schedules for the next several weeks.
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