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TUSCALOOSA, Ala. — Discovery of an antibiotic's capacity to improve cell function in laboratory tests is providing movement disorder researchers with leads to more desirable molecules with potentially similar traits, according to University of Alabama scientists co-authoring a paper publishing March 10 in the journal Disease Models & Mechanisms.
"It's our hope that this discovery serves as the impetus for a proper clinical trial to evaluate the potential of drugs like ampicillin for early-onset torsion dystonia," said Dr. Guy Caldwell, associate professor of biological sciences at The University of Alabama.
Dystonia is, like Parkinson's disease, a movement disorder. Combined, this class of diseases affects millions worldwide. People with early-onset dystonia have one good copy of the gene DYT1, and one problematic copy, in their DNA. These genes contain the information to make a protein called torsinA.
"When proteins go bad, they often cause disease, but they always have a normal function in our cells," Guy Caldwell said. "We looked to find molecules — not necessarily that reversed the mutated form of the protein — but instead enhanced the normal activity of the protein, thereby overcoming the deficiency caused by the mutant."
The UA researchers discovered that ampicillin, a common antibiotic of the penicillin group, serves to activate torsinA, which, in its normal form, appears to protect cells from stresses, such as protein misfolding ? a problem known to impact various movement disorders.
Using a nematode animal model designed to evaluate torsinA activity, the UA lab rapidly screened through hundreds of compounds to identify those that were most effective at enhancing torsinA's normally protective function.
"From there, we collaborated with researchers at Harvard and UAB to validate our findings in human patient cells and mice," said Dr. Kim Caldwell, associate professor of biological sciences at UA.
"In human dystonia patient cells, ampicillin was efficacious and restored the patient cells back to the normal function," Kim Caldwell said. "And, the drug restored normal movement to mice that were genetic mimics of dystonia."
Collaborators in the UA-led study were Drs. Xandra O. Breakefield and her colleagues at Harvard and Yuqing Li and his colleagues at The University of Alabama at Birmingham, known as UAB. Dr. Songsong Cao, a former doctoral student in the Caldwell Lab, is the study's lead author; two UA doctoral students, Alexander J. Burdette and Pan Chen; and one former UA student, Amber Clark Buckley, are among the co-authors.
Furthermore, the research shows ampicillin enhances the capacity of torsinA to protect, within animal models, the neurons which produce dopamine from dying. The death of these neurons in human brains leads to the hallmark symptoms of Parkinson's disease.
In a statement accompanying the paper, the researchers caution against the long-term use of an antibiotic in disease treatment.
"We have taken ampicillin and used that as a base structure to find things that work like ampicillin but which aren't ampicillin," Guy Caldwell said. "Finding molecules that are not antibiotic and still have the capacity to activate torsinA has been an ongoing effort of our lab, and we have some exciting leads in that direction."
UA filed patents covering the use of antibiotics and other novel chemicals as activators of torsinA for treatment of dystonia and other diseases, including Parkinson's disease. The University has also entered into a collaborative research and licensing agreement with QRxPharma, a clinical stage pharmaceutical company, to identify, develop and commercially exploit new torsinA activator drugs.
The UA/QRxPharma research program is directed at re-engineering existing drug therapies for new clinical applications and identifying new drug candidates for uses including the treatment of dystonia, Parkinson's disease and other neurological disorders.
The project exemplifies, the researchers said, how disease model systems can be used to accelerate the development of gene and drug discovery and bring pharmaceuticals more quickly to the clinical trial stage.
Bringing a drug that does not already have FDA approval from the research and development stage to a patient takes an estimated 12 years and $800 million dollars, said Kim Caldwell. By evaluating the potential of molecules already pre-screened for toxicity and that have FDA approval provides a potentially quicker route to clinical trials.
"What we were hoping to do was circumvent a lot of the cost in bringing pharmaceutical help to dystonia patients," Kim Caldwell said.
The research was supported by the Bachmann-Strauss Dystonia and Parkinson Foundation, Dystonia Medical Research Foundation, the Jack Fasciana Fund for Dystonia Research and the National Institutes of Health.
UA's department of biological sciences is part of the College of Arts and Sciences, the University's largest division and the largest liberal arts college in the state. Students from the College have won numerous national awards including Rhodes Scholarships, Goldwater Scholarships and memberships on the USA Today Academic All American Team.
This work is published in Issue 3/4 of Volume 3 in the medical research journal Disease Models and Mechanisms (DMM) http://dmm.biologists.org.


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by Chris
Lego Boba Fett Costume Photo 6 of 10
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This homemade costume for boys entered our 2014 Halloween Costume Contest.
A word from Keith, the 'Lego Boba Fett' costume creator:
My son is a huge Lego fan, therefore, I'm a huge Lego fan. I've always been a great fan of Star Wars, therefore, my son is a fan of Star Wars. With that said, he... Read more »
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subset: commoncrawl


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Modern Quilts
After having some painful dental work done today, I dropped by the library to pick up a couple of books. maybe I should apply GTD to crafting I've had The Modern Quilt Workshop on my "interested" list for a while. I kept coming across really awesome quilts on flickr from it. Just a few examples […]Read More..>>


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So, I thought I'd have some fun with the new Mercenary Heroes. I first turned all of my alternate characters into heroes and had fun for a while, but then I read this line on the Guild Wars Wiki:
A quick way of creating mercenaries of any profession would be to create a PvP character (already at level 20), give them appropriate armor, and register them. Delete the PvP character and create a new one in the profession of choice. With enough mercenary credits, you can create up to seven mercenaries of each profession.
So basically, you can make pretty much how ever many of whatever you want. I decided to take this opportunity to make a clone army.
I plan to take them vanquishing when I have enough money to equip them. For now they have no runes or insignia. I managed to get them all weapons at least. And I did take them out for a spin. I completed Vizunah Square in HM using the 2 Man Discordway build from PvXwiki. It could use a bit of tweaking, but otherwise it worked just fine. Vizunah isn't really geared for Discordway so much as MM and AoE. But lemmie tell you, it was kinda cool being one player with 15 heroes/henchies, 2 NPCs, and about 25 minions. Those afflicted never saw us coming.


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If asked to list the ingredients of a well-made New York-style pizza, most would begin by rattling off the usual suspects: a hand-tossed crust, a delicious tomato sauce and fresh mozzarella. Few would start by mentioning the one ingredient that many insist is critical in making a New York-style pizza pie: the water.
New York City has long been praised for its water. Last year, we wrote about a company called Tap'd NY, which was openly bottling New York's tap water for sale. And, perhaps not surprisingly, people were buying it.
Now, many restaurants outside of New York are using the same water to make their pizza, bagels and breads, thanks to the Famous New York Baking Water Corp. The company has created a water filtration system that yields water with a similar profile to New York's acclaimed water, which is then used by bakers and chefs to produce foods similar to those found in New York.
The water can also be used in sauces, soups or other dishes that aren't exclusively thought of as "New York" foods. The company claims that the water is similar to New York's water from a century ago, "before pollutants and contaminants invaded the water supply." Now, the company says, restaurateurs can use this same great-tasting water without worrying about contaminants and impurities.


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Ol' Myrt here has just received two cell phone calls from researchers at the the Family History Library in Salt Lake City, Utah who report the building is being evacuated. The alarm sounding in the background was readily apparent. At the time of the first cell phone call, Ol' Myrt here was on a conference call on my other line with someone at the Library. The alarms interrupted, and our virtual meeting was cut short.
I've contacted the local www.ksl.com television station to determine the cause, but the information has only come to their attention by my phone call.
I will not speculate as to the cause. However, if you are in Salt Lake City for research at the Family History Library, you might want to rethink your plans today, and watch for updates on the local news.
Ol' Myrt here will keep you informed.
Happy family tree climbing!
Myrt :)
Your friend in genealogy.
DearMYRTLE's Family History Hour
Family History Expos Genealogy Podcasts
DearMYRTLE's Facebook® Group Message Board
© 2009 Pat Richley All Rights Reserved.
This and previous blog entries are fully searchable by going to http://blog.dearmyrtle.com . Myrt welcomes queries and research challenges, but regrets she is unable to answer each personally.


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eBattalion, developers of FLIP and Nanoids, are now running a contest where one lucky (and skilled) winner will take home an iPad. The rules are pretty straight forward: play their latest game Doodle Run and obtain the high score by surviving longer than your competitors. The longer you're able to stay alive, the higher your score.
Run through multiple doodle themes, including Rain, Snow, Day, and Night. Grab a bazooka and mow down zombies and other dangerous obstacles. Jump into an oversized bullet and destroy everything in your path. Doodle Run is a pickup-and-play game that will have you coming back for more and more.
The iPad up for grabs will be the 16GBÂ WiFi model and all scores must be posted before April 30th. If you're not sick of doodle type games yet and buying the iPad come launch date is out of the question, picking up a copy of Doodle Run for $0.99 and trying your luck/skill could well be your ticket to owning one. Full contest rules after the break.
eBattalion, Doodle Run – $0.99
Update: Soma Games is also running an iPad contest with their game G: Into the Rain. Contest details can be found here


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Invite friends and acquaintances and experience the great atmosphere at a jewellery presentation. It's up to you whether to have your party at home, at a club, an association or a company. We always reward your commitment with attractive host gifts and special offers.
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Imani Winds in Tiny Desk Concert
May 23, 2013 Imani Winds' members play David to Igor Stravinsky's imposing Goliath, as they shrink the massive Rite of Spring down to size in a rendition for just five wind instruments. The result is an epic in miniature — and a performance perfect for a Tiny Desk.
When Igor Stravinsky began composing The Rite of Spring, his ballet for vast symphonic forces, he could hear the music in his head but couldn't quite figure out how to write it down. It was just too complicated.
Today, 100 years after The Rite's premiere, the fearless musicians of Imani Winds make it all sound remarkably easy, given that they've condensed Stravinsky's massive walls of sound down to just five instruments: bassoon, clarinet, flute (doubling on piccolo), oboe and French horn.
Make no mistake: Many of the jagged rhythms and crunching chords remain viscerally intact, albeit on a more intimate scale. As the group huddled behind Bob Boilen's desk, bassoonist Monica Ellis noted the opposing ratios, saying, "It's apropos in some strange way that we are playing one of the most massive pieces in some of the smallest instrumentation in one of the smallest settings that it could possibly be played in."
The setting might be small, but in this clever arrangement by Jonathan Russell, we learn that a wind quintet, when called upon, can make a mighty and sonorous wail. Just listen to how the Imanis cap off "Dances of the Young Girls" with the entire quintet in full cry (at about 4:30 into the video). The bassoon repeats a fat bass line while the clarinet runs its snaky scales. The piccolo, in piercing chirps, serves as a foil to a frenzied oboe and snarling "whoops" from the French horn.
But not everything in The Rite is all pound and grind. Stravinsky's transparent introduction, almost impressionistic, is a fluttering aviary of winds — even in the original — with individual colorings for each instrument. It's all rendered beautifully here by Imani Winds, musicians brave enough to play David to Igor Stravinsky's imposing Goliath.
Selections from The Rite of Spring:
- Introduction
- Augurs of Spring
- Dances of the Young Girls
- Ritual of Abduction
- Spring Rounds
- Dance of the Earth
- Sacrificial Dance: The Chosen One
Producers: Tom Huizenga, Stephen Thompson; Editor: Gabriella Garcia-Pardo; Audio Engineer: Kevin Wait; Videographers: Denise DeBelius, Becky Lettenberger, Stephen Thompson; photo by Marie McGrory/NPR


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Interior Light
1 H: 3' 7.3" - 110cm W: 11.8'' - 30cm D: 1.38'' - 3.5cm
acrylic and imitation silver leaf on canvas
This triptych is a delicate, shimmering work inspired by how light refracts and dances. The colours are soft blues and pinks with imitation silver leaf and it flickers with candle, crystal and chandelier shapes. It is entrancing when the light shines on it.
Playing on the Sand as a Child
1'8" x
1'8" -
51cm x 51cm
acrylic on canvas
Some of my happiest times as a child were on holiday with my grandparents in Devon. This painting is about the freedom of childhood on a beach when the sun seemed always to shine.
Colour Cascades
10'' x
12'' -
25.3cm x 30.5cm
acrylic on canvas
This energetic little piece captures the vibrancy of iridescent colours and so shines very differently in different lights.
'Cast Thy Nighted Colour Off', Hamlet I.ii.68
1' 7.7" x
1' 7.7" -
50cm x 50cm
acrylic on canvas
This is a vibrant painting full of energy and joie de vivre, inspired by the quote from Hamlet. It is about having the courage to embrace colour again when maybe you have been through a colourless time.


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Troy Fresch has not received any gifts yet
Hi Troy,
It looks like I won't be able to play during the week. Let me know if you are available over the weekend and we can hit.
Hey Troy,
Sounds good. Lets play when the weather gets better. The courts at 19th and Irvine are perfect. Nights during the week and anytime during the weekend are best for me. Talk to you soon.
© 2020 Created by Mark / The Mayor. Powered by


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Follow RFF News on your cell phone. Text follow rff to 40404 you will receive txt messages with RFF News
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These dates may be delayed due to PGA tour golf on CBS,2/19 (Premiere), 4/8, 4/15, 4/22, 4/29, 5/6Source: http://www.pgatour.com/r/schedule/And, I'm new here
Revised start times for tonight's CBS programs: 60 Minutes (7:21pm ET), Amazing Race (8:21pm ET), The Good Wife (9:21pm ET) and CSI: Miami (10:21pm ET) due to CBS Sports live coverage of the PGA Tour's Northern Trust Open.
Quote from: georgiapeach on January 26, 2012, 03:24:31 PMUgh. Looks like CMA 4/1. Anything else??That seems right, because they like the spring season to end on Mother's Day now and it would end on May 6th without that break.
Ugh. Looks like CMA 4/1. Anything else??
That is no longer necessarily the case, Survivor got stuck with it last time.
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Wednesday, January 13, 2010
Wordless Wednesday
3 comments:
You have snow today, that is too bad, we had sun, now clouds. Heather, we should have gotten together with our pictures of the Revolutionary War soldiers. I liked your piece. I posted mine at 7:30 and it didn't go through until 5 hrs. later!ReplyDelete
Reminds me of a promotional piece to sell the sleds! Thanks for sharing!ReplyDelete
Bill ;-)
Author of "13 Ways to Tell Your Ancestor Stories"
I love the sled, the hat, and the pose! Adorable!ReplyDelete
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preferably at night, with the 'shapeless universe' outside expunged by darkness. Warmed by the pools of light that spill from his lamps, he does not even need to read: the smell of the wooden shelves and 'the musky perfume of the leather bindings' is enough to pacify him and prepare him for sleep....Within his global, multilingual book collection, he can effortlessly travel in both time and space.
What emerges clearly from Giddings' account is a portrait of a courageous activist who desperately longed for recognition and credit but found herself instead perpetually frustrated when passed over for office or denied the praise she believed she deserved. One of the many strengths of Giddings's biography is her reluctance to either romanticize or minimize Wells' contributions. She is also appropriately attentive to the broader canvas of black politics, continually situating Wells in a spectrum of black perspectives that can no longer be reduced to Booker T. Washington's accommodationism and W.E.B. DuBois' militancy. If excessively detailed at times, "Ida: A Sword Among Lions" is nevertheless a skillfully constructed and often moving account of a life and a time whose complexity is always central to its story.


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Les Paul exhibit opens in Waukesha
Exhibit brings visitors up close with Les Paul's music, inventions
After years of planning, Waukesha's Les Paul exhibit opened to the public for the first time Sunday.
Organizers said the Les Paul Experience will bring visitors up close and personal to the Wisconsin native who changed the face of music around the world.
Jack Larson was born long after the wizard of Waukesha helped pioneer the solid-body electric guitar, but he said the new museum exhibit is introducing him to Les Paul's music and inventions.
"This is really interesting because personally, I've always liked the guitar, so this is a cool way to learn more about the electric guitar and the evolution of music. And Les Paul seems like a really cool guy, so I'm excited to learn more about him here," said Larson.
Les Paul was buried in Waukesha, where he was born. The Les Paul Experience is part of the Waukesha County Museum, introducing artifacts from the famous guitarist's personal collection.
"We have priceless guitars. We have things that Les Paul actually wore, like his Les Paul Hard Rock Cafe bomber jacket. We have items that you will not see anywhere else, like his original sound-on-sound Ampex recording gear," said Kirsten Lee Villegas, president of the Waukesha County Museum.
Les Paul created electric guitar effects, which are still used by guitarists around the world.
"I knew he was from Wisconsin, but I had no idea he was this inventive. The solid-body guitar I knew, but I didn't know all the multitrack recording. It's wonderful," said visitor Ray Szohr.
The exhibit is open from 10 a.m. to 4:30 p.m. Tuesday through Saturday.


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If you make a change to the space that would require a lot of work to reverse (or you would rather people didn't reverse), record it here. Just hit "edit" at the top of the page, and add away. Don't worry too much about formatting, I'll fix it.
If you put click on the signature button in the editor, (the squiggle button next to the crossed out W and the horizontal line) you'll leave your name and a time and date.
Separate entries with "----", precede them with --. See other entries for examples. Add them to the top.
If you see something that needs to be fixed, record it on Bugs
--Malaclyps 03:09, 26 April 2012 (UTC)
* Delivery of USB enclosures, Francisco, Catherine helped. * Probed at broken buzzer at top -- no wires seem loose within the main door/listen/talk box.
--Malaclyps 19:22, 23 April 2012 (UTC)
* Martin cleaned up lasercutter, taught Rayc tips on how to clean it.
--220.127.116.11 02:03, 22 April 2012 (UTC)
* Working lights in Turing!
--Malaclyps 19:09, 21 April 2012 (UTC)
* Air compressor for laser cutter needed new brass fitting, fixed by Martin B. (who also cleaned around) * RetinaEngrave downloaded and re-installed, printer driver now working from InkScape ** Remember! RetinaEngrave must be running in order to use it as a printer driver. Windows will not run the 'driver' for you. **
--Malaclyps 05:29, 21 April 2012 (UTC)
* The noisebridge-api now installs as its own Debian package on pony.
--Malaclyps 00:12, 21 April 2012 (UTC)
* Wood brought in by User:miloh for third electronics bench. Woohoo!
--Malaclyps 22:41, 20 April 2012 (UTC)
* We now have Dead Drop in the gatephone, courtesy of James
--Malaclyps 20:47, 20 April 2012 (UTC)
* Cleaned out tar in gateway entry callbox.
* Filed bug report via discuss re: broken buzzer


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CARLSBAD, Calif., Nov. 7, 2012 /PRNewswire/ -- Life Technologies Corporation (NASDAQ: LIFE) today announces the QuantStudio™ 3D Digital PCR System, a scalable, chip-based instrument that is democratizing this technology for a rapidly growing market. Featuring a simple workflow with minimal hands-on time, the benchtop platform is disruptively priced at $30,000 -- enabling access to a broader community. The system is currently with early access customers and commercial shipments will begin in the first half of 2013.
Designed with a scalable architecture, the QuantStudio™ 3D Digital PCR System's first generation chips enable up to 20,000 data points in a single run -- coverage that satisfies the needs for most digital PCR applications today. The capacity of future chips will increase exponentially to meet increasing demands of the research community.
The new platform is the latest addition to a growing line of QuantStudio™ digital qPCR instruments from Life Technologies. It complements the QuantStudio™ 12K Flex Real-Time PCR System, which the company launched earlier this year and provides the highest throughput capability for digital PCR on the market.
Considered until recently a niche segment, the digital PCR market is expected to grow to nearly $250 million globally by 2016. Researchers worldwide use real-time PCR (polymerase chain reaction) to amplify and quantify nucleic acids. Digital PCR takes researchers beyond the limits of real-time PCR for applications that require absolute quantitation of targeted DNA molecules. Additionally, Life's simple workflow and chip-based platform reduce the risk of sample contamination and loss of DNA normally associated with droplet-based systems. The technology is ideal for accurately detecting rare mutations important in cancer or infectious diseases – the equivalent to finding a needle in a haystack. It is also increasingly used as a mechanism to perform quality control experiments on next generation sequencing libraries.
"The QuantStudio™ 3D Digital PCR System is the latest revolutionary platform from the team that has delivered every market-leading technology in qPCR," says Chris Linthwaite, Head of Genetic Analysis, Life Technologies. "By making this novel platform accessible to all labs, we are enabling the democratization of digital PCR and helping the scientific community expand the utilization of this technology in disease research and applications beyond."
Prior to commercial launch, Life Technologies is making the QuantStudio™ 3D Digital PCR System available to early access users through the Digital PCR Applications Grant Program, which will fund 20 research projects that demonstrate innovative applications for the instrument. Five grand prize winners chosen among the winning proposals will receive a QuantStudio™ 3D Digital PCR System. For details on submitting a proposal, visit www.lifetechnologies.com/dpcrgrant.
Life Technologies will host presentations and a poster session from early access users of the system on Nov. 8 at the American Society of Human Genetics conference (ASHG). For more information on these talks, visit Life's ASHG website. The system will be officially unveiled during Explore Art and Science with Life Technologies, a customer event that will showcase the company's latest solutions from the Ion Torrent and Genetic Analysis divisions at the San Francisco Museum of Modern Art on Nov. 7 from 7-10:30 p.m. For invitations to the event or for more information, visit the Life Technologies booth (# 601) during ASGH.
The QuantStudio™ 3D Digital PCR System is For Research Use Only, not intended for diagnostic purposes.
About Life Technologies
Life Technologies Corporation (NASDAQ: LIFE) is a global biotechnology company with customers in more than 160 countries using its innovative solutions to solve some of today's most difficult scientific challenges. Quality and innovation are accessible to every lab with its reliable and easy-to-use solutions spanning the biological spectrum with more than 50,000 products for agricultural biotechnology, translational research, molecular medicine and diagnostics, stem cell-based therapies, forensics, food safety and animal health. Its systems, reagents and consumables represent some of the most cited brands in scientific research including: Ion Torrent™, Applied Biosystems®, Invitrogen™, GIBCO®, Ambion®, Molecular Probes®, Novex®, and TaqMan®. Life Technologies employs approximately 10,400 people and upholds its ongoing commitment to innovation with more than 4,000 patents and exclusive licenses. LIFE had sales of $3.7 billion in 2011. Visit us at our website: http://www.lifetechnologies.com.
Life Technologies' Safe Harbor Statement
This press release includes forward-looking statements about our anticipated results that involve risks and uncertainties. Some of the information contained in this press release, including, but not limited to, statements as to industry trends and Life Technologies' plans, objectives, expectations and strategy for its business, contains forward-looking statements that are subject to risks and uncertainties that could cause actual results or events to differ materially from those expressed or implied by such forward-looking statements. Any statements that are not statements of historical fact are forward-looking statements. When used, the words "believe," "plan," "intend," "anticipate," "target," "estimate," "expect" and the like, and/or future tense or conditional constructions ("will," "may," "could," "should," etc.), or similar expressions, identify certain of these forward-looking statements. Important factors which could cause actual results to differ materially from those in the forward-looking statements are detailed in filings made by Life Technologies with the Securities and Exchange Commission. Life Technologies undertakes no obligation to update or revise any such forward-looking statements to reflect subsequent events or circumstances.
(Logo: http://photos.prnewswire.com/prnh/20110216/MM49339LOGO)
Life Technologies Contact
Mauricio Minotta
760-805-5266 (mobile)
|SOURCE Life Technologies
Copyright©2012 PR Newswire.
All rights reserved


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C17FE744BL 2-IN-1 TOTE BAG AND SLING (Blue)
This CAVA tote features a classic design with double top handles and comes with a matching sling bag.
Made with sturdy, synthetic leather material and top quality machining, the bag is designed to meet the needs of the stylish woman who's always on the go. Locally manufactured in the Philippines, one can expect that the product has been quality-checked with utmost attention to detail.
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text:
I believe that these methods of slaughter are barbaric, cause needless suffering to animals, are sticking two fingers up to hard-won animal welfare laws and have no place in civilized society.
Also, (in the UK at least) much of halal meat is not labelled as such and on sale in major supermarkets. Subway, KFC, Nandos and many other fast food chains and restaurants are selling halal meat in selected outlets.
Quite simply, cultural suicide and an affront to animal welfare.
Views: 494
Yeah, they SHOULD be banned ... but the second you try to do so, you'll get muslims and jews screaming bloody murder about how their religious rights are being trampled on and about this is how their god wants their meat slaughtered because their holy book sez so, et cetera, et cetera.
So long as their religions exist, this argument is going to go on. Not being contrary here; just being real.
I agree that that is immediately the reaction you get but it doesn't mean we shouldn't try. In the meantime we should, at the very least, inform non jews and muslims exactly what halal and kosher meat is, how it is being sold to them without their knowledge and encourage them to vote with their feet. Supermarkets and restaurants should make it clear if they sell it.
A French friend told me that halal meat is sold in most french stores, and it is not labeled. That way the muslims are assured that the animals they eat have been properly tortured, but the other carnists have no idea how the animals were treated.
How do you slaughter meat? Isn't meat the muscle of someone who has already been murdered? If we talk about animals as though they are just meat, how can we work up any empathy for them?
i agree with you, Loren, that when muslims and jews both start yelling about the same thing, we haven't a "prayer". ha, ha. With the help of the sadly corruptible ACLU, they stopped a citizen's campaign in progressive San francisco,to outlaw the sexual mutilation of baby boys - circumcision.
I agree, but that is not what I'm discussing.
No, it is NOT what I'm discussing. The reform of the entire meat industry is a whole other topic.
In the UK, halal and kosher slaughtering methods are, as far as I'm aware, exempt from the regulations governing slaughtering which others have to adhere to.
Of course it's a religious issue! This is the Atheist Nexus forum after all isn't it?!! Demanding exemption from animal welfare laws on superstitious, or any grounds is ludicrous and a backward step. And when this meat is being consumed by us, often without our knowledge, it is most definitely a religious issue.
Nerd, as you know, I regularly piss off the carnist atheists!
Maybe not banned, clearly labeled as you guys have mentioned already I do agree with, if Americans are educated about what exactly is going on they may have a severe drop in sales, and stop offering all together. It's the companie's decision to sell ultimatly, if no one buys but a few of the Jews and muslims, they wont sell.
Why not ban it? At the very LEAST we should be informing others and persuading companies not to sell it.
Heres the thing... YouTube videos aside if you really read up on the subject both Halal and Kosher slaughtering methods are in part, at least, designed to minimize the suffering of the animal. Even as an atheist I personally opt to buy kosher and halal meats because the animals are often treated much better in life because of the rules regarding the health and welfare of the animal at the time of slaughter.
I'm very well read up the subject thanks and do not get my info from YouTube. The slaughtering methods have nothing whatever to do with minimising suffering, despite what Muslim and Jewish organisations say. The methods are entirely due to religious superstition.
Every single animal welfare organisation that has commented on the subject condemns it as causing unnecessary suffering. To give just two examples of expert opinion of animal welfare (in the UK at least):
The Farm Animal Welfare Council (FAWC) recommended that killing animals without stunning them first caused severe suffering. FAWC chairperson, Dr Judy MacArthur Clark: "This is a major incision into the animal and to say that it doesn't suffer is quite ridiculous." Compassion in World Farming backed the call, saying: "We believe that the law must be changed to require all animals to be stunned before slaughter."
My apologies for being frank but I'm appalled that an atheist would actively SUPPORT these barbaric practices carried out for no other reason than religious superstition and actually believe they are more humane than pre-stunning which has been in place for decades, for good reason.
Please allow me to adress each of these points...
* You site "every single animal welfare organization", well there are dozens of studies that do not support this opinion, they are however not performed by animal welfare organizations. And you missed my point entirely, which is that I could care less about the religious aspects, I simply appreciate the fact the the animals usually are treated better in life than those sent through the mass slaughter system.
* The beauty of being an atheist is that I don't have to follow other people's made up rules when it comes to my own sense of morality. Your comment appalls me, as it sounds exactly like the kind of crap religious people say all the time " how can you call yourself a Christian if you do X, Y or Z?" I am free to support or not anything I wish for whatever reasons I wish.
I could go on and on but I see no reason. I don't think you really wanted an open discussion and exchange of ideas, I think you just wanted people to agree with you. Some of us did not agree and this has caused you to become indignant.
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text:
National Fertility Survey, 1975 (ICPSR 4334)
Version Date: Feb 23, 2007 View help for published
Principal Investigator(s): View help for Principal Investigator(s)
Charles F. Westoff, Princeton University. Office of Population Research; Norman B. Ryder, Princeton University. Office of Population Research
Version V1
Summary View help for Summary
The 1975 National Fertility Survey was the fifth in a series of studies (National Fertility Surveys/Growth of American Families) examining marital fertility and family planning. The 1975 version of the National Fertility Survey is unique from the surveys that preceded it (1955, 1960, 1965, and 1970) in that it is longitudinal, incorporating respondents that first participated in the 1970 survey. Respondents were queried on the following main topics: family ideals, work history, family life and women's rights, history of live births and miscarriages/stillbirths, adoptions, abortions, contraception history, family planning and sterilization operations, fertility issues, and current population problems. Questions pertaining to family ideals included preferred family size, preferences with respect to the gender of children, and ideal ages for having first and last children. Regarding work history, respondents were asked about all paid employment since January, 1970, motivation for employment, whether they were currently employed, and whether future employment was probable. Respondents were asked a number of questions about family life and women's rights including whether preschool-aged children suffer if the mother works, if children could have warm relationships with a working mother, if the father should work outside of the home and the mother stay home, whether men and women should have the same job opportunities and be paid the same for doing the same job, and if men and women should receive equal consideration for top-level positions. With respect to pregnancy history, respondents were asked if they had ever had a baby, how many total live births they had had, the date of first live birth, duration of the pregnancy, and about breastfeeding practices. Respondents were also asked about any miscarriages or stillbirths they had including total number and after how many months of pregnancy. Respondents were asked if they had ever legally adopted a child, total number of children they had adopted, date of adoption, and gender of adopted child. Regarding abortion, respondents were asked if they ever had had an abortion, and how many total abortions they had had, after how many months of pregnancy. In addition, respondents were asked about the acceptability of abortion under different circumstances such as if the mother's health was in danger, the pregnancy was the result of rape, or if there was an expectation that the unborn child would be born with a deformity. With respect to contraceptive practices, respondents were asked what methods of contraceptive they had used both past and present, the effectiveness of each of the various methods, and reasons for discontinuing use of the different methods. Regarding family planning, respondents were asked whether they intended to have additional children or not, and about the possibility of changing their minds with respect to having additional children. Respondents were also asked about sterilization operations, including their general attitudes toward male and female sterilization, whether they had undergone a sterilization operation, and if so, what kind of operation. Regarding fertility issues, respondents were asked if future pregnancies were physically possible, whether or not they had intended to have more children prior to learning of physical incapabilities, how many children were intended at that time, whether or not their spouse had had a sterilization operation, and if the operation was to prevent future pregnancies. Respondents were asked about current population problems, whether or not population growth in the United States and in the world was a problem, whether American cities and states had the right to limit the number of incoming inhabitants, and whether limits should be placed on immigration. The dataset includes various demographic and income variables including age, age of husband, level of education, religion, nationality, occupation, work history, total family income, and financial conditions.
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The ASCII data file for this study originally had a LRECL of 2,480. This file contained many unused columns that were filled with zeros. During the processing of this study, the unused columns were removed resulting in a new ASCII data file with an LRECL of 1,880.
Certain codes were discovered to be undocumented. A detailed listing of all undocumented codes can be found in the processing notes accompanying the study documentation.
- Additional information regarding this study is available from the Office of Population Research at Princeton University and the Data and Program Library Service at University of Wisconsin-Madison. Information about the other studies in the National Fertility Surveys/Growth of American Families series can be found at Princeton's Office of Population Research and the Population Studies Center at the University of Michigan.
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The data comes from a national probability sample of continuously married (once married and currently married) women who were White, married fewer than 25 years and before the age of 25, and whose husbands also were once married. For marriages lasting more than five years, the sample consists of eligible women selected from the 1970 National Fertility Survey sample who were reinterviewed approximately five years after the 1970 survey. In addition, a proportionate sample of new respondents was added to represent marriages that occurred after the year 1970. There were 1,042 new respondents in the 1975 sample, and there were 2,361 respondents who were reinterviewed from the 1970 sample, for a total of 3,403 respondents.
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Continuously married, White women in the United States.
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- Westoff, Charles F., and Norman B. Ryder. National Fertility Survey, 1975. ICPSR04334-v1. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2007-02-23. http://doi.org/10.3886/ICPSR04334.v1
Data in this collection are available only to users at ICPSR member institutions.
This study is provided by ICPSR. ICPSR provides leadership and training in data access, curation, and methods of analysis for a diverse and expanding social science research community.


text:
Prominent USA scientist destroys the myth about curing baldness
Recently, the scientific world was gravely shocked by an unexpected news following decades of in-depth research – BALDNESS IS NOW CURABLE!
Doctor A. Chan is an American born Chinese who graduated from Dermatology at Stanford University School of Medicine. After her honored graduation, Dr. Chan spent over 20 years working as a Research Supervisor of Dermatology clinical trials aimed at finding a remedy for a number of severe skin conditions thought to be incurable. One of those conditions was baldness – the partial or complete lack of hair growth.
After decades of testing the effect of various compounds that stimulate hair growth, Dr. Chan finally discovered the only missing ingredient of a powerful remedy kept secret for almost 2 decades. That was an extremely rare herb that grows only in few special places in the whole world and its distribution and usage have been rigorously restricted until now. "When mixed with other curing elements, this herb literally performs some sort ofmagic to the scalp – it covers it with newly grown hair!", Dr. Chan explained yesterday during a medical conference with colleagues held in Chicago, USA.
After 20 years of research and clinical trials, Dr. Chan has finally come up with a unique remedy that cures baldness. Her phenomenal product has undergone numerous clinical trials and according to scientific estimations it shows 98.7% success in curing baldness and thin hair. Furthermore, the solution not only "brings hair back to life" but it also improves its quality immensely by nurturing the scalp and reconstructing the hair follicle entirely, so that hair starts growing thicker in a three times faster pace.


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text:
Mathes: The beautiful soul of Dave Brubeck
Dave Brubeck was a rare thing in the music world, a complete innovator and true artist who at the same time was one of the most joyful, kind and family oriented artists ever. He adored his wife and children, all of whom were great musicians, truly great musicians. His son Chris and I are close and he is one of our leading arranger composers on the jazz, pop and classical borders.
I musically direct the Kennedy Center Honors. When we honored Dave, I did a big arrangement of "Take Five" for the Army Big Band: Jon Faddis, Bill Charlap and Herbie Hancock. The big surprise at the end of it was that all of Dave's sons were behind a wall and he did not know they were there to celebrate him. The concept of the Kennedy Center Honors is that in the presence of the president, five great American artists are feted at the State Department and the White House. On Sunday night, at the end of a big weekend of celebration, celebrities and artists speak about and perform for these great artists. Dave's segment was extraordinary. His composition "The Duke," famously recorded by Miles Davis, was played as well as many others.
The highlight, though, was this surprise for Dave. Dan, Matthew, Darius and Chris Brubeck were behind a wall that was removed to reveal them, and Dave, a religious and sweet-spoken man, clearly mouthed the words "Son of a bitch" and wiped away tears.
He was always kind to me. I had begun my career as an orchestrator and composer writing a large choral and orchestral work for the Greenwich Choral Society. At a party after my premiere Dave attended with his wondrous wife, Iola, he was so remarkably encouraging. He told me about all these choral pieces he had written and I was enthralled at how this great jazz legend had immersed himself in Bach and had written all these fugues. He then sent me a bunch of cassettes of these pieces, which I still have.
He wrote me personally after the Kennedy Center Honors to thank me for my hard work and to tell me how moved and thrilled he was with his tribute. This is rare to hear from a legend after the fact. His great innovation was bringing in odd time signatures into jazz. "Take Five," which he influenced but was actually written by Dave Brubeck Band member Paul Desmond, was a piece with five beats per bar (Waltz time is three beats per measure and most music is in four beats per measure). "Blue Rondo A La Turk" is in 9/8-9 beats per bar. These were remarkably catchy and joyous compositions with infectious patterns and melodic fragments and this came directly from Brubeck.
He loved Duke Ellington and was a very early champion of civil rights. As I write this I am tearing up because I am thinking of Chris, my friend and his son, who inherited both his dad's musical greatness and also his extraordinarily large heart. I can tell you that of almost everybody I have met in the music business, Dave was the most beautiful soul of all. I end with a story about this heart of his.
Bill Charlap, the great jazz pianist, told me a story about playing at a number of festivals with Dave, Bill being in one of the other bands. He remembers that these festivals would put rock performers such as Santana, Dr. John and the Doobie Brothers on the same stage as older jazz artists, even occasionally having the rock bands do the warm-up set.
The problem with this was that inevitably, no matter how great the jazz musicians were, it was very tricky for them to compete with the power, volume and sheer visceral, popular cultural groove of these bands. A number of the artists grumbled intensely about how awful this was. There was an immense amount of anger brewing in the ranks. Bill referred to it as being fairly poisonous.
And then there was Dave. One night Dr. John was the warmup act for Dave and Dr. John was rocking out loud and strong on one of his hits, perhaps "Right Place, Wrong Time" or something like it. Bill was pacing back and forth backstage when he spotted Dave Brubeck standing right off stage. Everyone else scheduled to play that evening was upset about following a loud rock set. Dave was standing right there taking in every note Dr. John played. He turned to Bill and Bill said he had never seen a bigger smile in his life. What did Dave say??
"Isn't Dr. John great? I love this!"
That says it all about Dave Brubeck. A great, great musician and a great, great man. He will be sorely missed.
A very sad day but his music will live on forever.
Award-winning singer, songwriter, producer and composer Rob Mathes lives in Greenwich.


text:
- changed status to resolved
Applied the patch in 52bb77ad5030
This is a copy of http://bugs.python.org/setuptools/issue70:
The attached patch for setuptools 0.6c9 replaces a shell callout to /usr/bin/sw_vers to using platform.mac_ver on OSX.
The primary reason for writing the patch is that gdb tends to cause havoc with calls to os.popen (the debugged process gets an signal and debugging gets aborted).
This patch makes it a lot more convenient to run "setup.py test" in a gdb session, without this patch I regularly have to re-run the tests several times until the callout to sw_vers succeeds.
Applied the patch in 52bb77ad5030


text: Health Information Exercise for Chronic Disease Relief by Carrie Myers Smith, BSEn Español (Spanish Version)Types of Exercise | Disease Impact For people who suffer from a chronic disease, exercise can decrease discomfort, improve daily functioning, and enhance overall quality of life. There are many activity choices. Overall, find something that you enjoy doing and a place that is comfortable for you to do it in. Although being physically active is good for anyone, some exercises provide specific benefits. Here is how different types of exercise can help people with specific chronic diseases. Types of ExerciseThere are 3 basic categories of exercise:Aerobic ExerciseThese are exercises that raise your heart rate through repetitive movement of large muscles groups. The 2 types of aerobic exercise are: Weightbearing—Your muscles work against the force of gravity. Examples include jogging, walking, and dancing. Nonweightbearing—The force of gravity does not play a major role. Examples include biking, swimming, and rowing.Strength Training ExerciseThese are exercises that increase the power, tone, and efficiency of individual muscles by contracting isolated muscles against resistance. An example is lifting weights. The increase in heart rate is short-lived compared to aerobic exercise.StretchingThese are exercises that improve or maintain the flexibility of your muscles. Good flexibility is important to keeping a full range of motion and decreasing your chances of injury. Ideally, you should stretch after each exercise session.Disease ImpactOverall, all 3 types of exercises are important in an effective program. However, the list below demonstrates how a certain types of exercise can directly impact your specific health condition.Heart Disease Researchers and healthcare professionals have found that regular exercise reduces the risk of having a heart attack, particularly for people with coronary artery disease (CAD). Specific benefits of exercise for people with heart disease include:Stronger heart muscleReduced cholesterolReduced plaque build-up inside the arteriesBetter weight and blood pressure controlType of exercise that can reduce risk of heart disease and heart attack: AerobicHigh CholesterolCholesterol is found in cells throughout your body. Although it tends to get a bad rap, cholesterol is actually essential for life. It only contributes to heart disease when you have too much of certain types of cholesterol or too little of other types. Exercise can help reduce cholesterol, and even better, it can help raise your HDL (good) cholesterol. Aim for at least 30 minutes of exercise most days of the week. Even short, 10-minute spurts of exercise can help. Exercise also has the added benefit of weight loss, which can also help to lower cholesterol levels.Type of exercise that has been shown to improve cholesterol levels: AerobicDiabetesDiabetes is a disorder of the body's insulin production and usage, and it is a major risk factor for coronary artery disease. If there is not enough insulin, glucose (fuel for all cells) cannot get from the blood to the cells. As a result, the body is essentially starved and the glucose builds up in the blood. Exercise can make the cells more sensitive to insulin, and more glucose can move from the blood into cells.Since exercise changes the way your body reacts to insulin, you may need to check your blood sugar before and after exercising. Talk to your doctor before you begin an exercise program to learn about what your levels should be.Types of exercise that influence insulin sensitivity and cardiovascular risk factors: Aerobic and strength trainingHigh Blood PressureThe risk of high blood pressure increases as we age. Exercise can help to lower your risk and even control your blood pressure if it's already high. Exercise helps with blood pressure by making your heart work more efficiently. This means your heart does not have to work as hard to pump blood, so there is less pressure on your arteries.A good target for blood pressure is 120/80 mm Hg. Adding moderate physical activities to your normal routines can help you get there. You should aim for at least 30 minutes of aerobic activity on most days of the week. Even several 10-minute spurts throughout the day can help.Types of exercise that have been shown to lower blood pressure: Aerobic and strength trainingStroke A stroke occurs when not enough blood is reaching part of the brain. This causes the cells in that area to die. People who have already had a stroke are at increased risk for recurrent stroke or other cardiovascular problems. A stroke can create some physical impairments. Exercise may improve strength and coordination of the affected muscles. Exercise recommendations may vary depending on the severity of the stroke and the person's limitations.Type of exercise for stroke recovery: Aerobic, strength training, and stretchingCancerStudies suggest that people with cancer who do not have depression have a better chance of survival than those who do. Exercise is a great way to avoid depression and improve your overall mood. It's not clear exactly how exercise impacts mood, but it probably works by causing the brain to release chemicals, like endorphins, and increase body temperature, which can have a calming effect.Types of exercise found to boost energy and mood: Aerobic and strength trainingLung DiseaseChronic obstructive pulmonary disease (COPD), including emphysema and chronic bronchitis, is the most common form of lung disease in adults. Exercise improves activity levels and decreases symptoms. Types of exercise shown to improve respiratory ability: AerobicArthritisContinuous motion is essential for the health of your joints, especially arthritic ones. Regular exercise promotes strength and flexibility, and helps preserve the resiliency of joint surfaces.Types of exercise shown to improve joint health: Nonweightbearing aerobic, strength training, and stretching (water exercises are ideal)OsteoporosisOsteoporosis is a bone-thinning disease that can lead to fractures. Weightbearing exercises maintain bone density and strength by tipping the balance in favor of bone formation. Weightbearing activities include walking, jogging, hiking, dancing, stair climbing, tennis, and other activities that you do while on your feet.Type of exercise shown to improve bone density: Weightbearing aerobic and strength trainingIn any condition, a well-rounded exercise program will have all 3 types of exercise involved. Aerobic exercise will increase your endurance and ability to get through longer workouts. Strength training will build muscle strength and allow you to tolerate higher intensities as well improve balance and agility. Stretching can decrease stiffness and increase mobility.Talk to your doctor before beginning any exercise program. You can also consult with an exercise specialist to help you develop a routine.RESOURCES:National Institutes of Healthhttp://www.nih.govThe American Orthopaedic Society for Sports Medicinehttp://www.aossm.orgRESOURCES:Canadian Society of Exercise Physiologyhttp://www.csep.caHealthy Canadianshttp://www.healthycanadians.gc.caReferencesDepression. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated February 11, 2016. Accessed March 23, 2016.Exercises for arthritis. Arthritis Foundation website. Available at: http://www.arthritis.org/living-with-arthritis/exercise/. Accessed March 23, 2016.Fagard RH. Exercise characteristics and the blood pressure response to dynamic physical training. Med Sci Sports Exerc 33. S484-S492; 2001.Gordon NF, Gulanick M, Costa F, Fletcher G, Franklin BA, Roth EJ, Shephard T. AHA scientific statement: Physical activity and exercise recommendations for stroke survivors. Circulation. 2004;109: 2031-2041. Circulation website. Available at: http://circ.ahajournals.org/content/109/16/2031.full. Accessed March 23, 2016.Junnila JL, Runkle GP. Coronary artery disease screening, treatment, and follow-up. Primary Care: Clinics in Office Practice. 2006 Dec; 33(4).Onitilo AA, Nietert PJ, Egede LE. Effect of depression on all-cause mortality in adults with cancer and differential effects by cancer site. Gen Hosp Psychiatry. 2006 Sep; 28(5): 396-402.Physical activity for cardiovascular disease prevention. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated December 21, 2015. Accessed March 23, 2016.Physical activity guidelines for Americans. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated January 9, 2013. Accessed March 23, 2016.Weightbearing exercise for women and girls. American Academy of Orthopaedic Surgeons Ortho Info website. Available at: http://orthoinfo.aaos.org/topic.cfm?topic=A00263. Updated October 2007. Accessed March 23, 2016.Last reviewed March 2016 by Michael Woods, MDPlease be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © EBSCO Publishing. All rights reserved.Editorial PolicyPrivacy PolicyTerms and ConditionsSupport


text:
Searching for Crusoe: A Journey Among the Last Real Islands
Ballantine Books, 2001 - Travel - 342 pages
They inspire feelings of great passion, serenity, and sometimes fear . . . they give people the opportunity to find themselves--or to lose their minds . . . they are revered as paradise or treated as junkyards . . . both haunted by and respectful of history . . . they are central to the myths and religions of many peoples throughout time . . . they provide a real, friendly community or the hell of repetitive social encounters . . . What is it about islands that has captivated millions of people around the world and through the centuries?
In a penetrating, brilliantly written book that weaves sociology, history, politics, personality, and ancient and popular culture into one compelling narrative, Thurston Clarke island-hops around the oceans of the world, searching for an explanation for the most passionate and enduring geographic love affair of all time--between humankind and islands.
Along the way Clarke visits the remote and silent Mas Ŕ Tierra, the island off the coast of Chile that inspired Defoe to write Robinson Crusoe; tropical Banda Neira, one of the Spice Islands, where its self-crowned prince hopes for nothing less than nutmeg's complete and glorious revival; sleepy, simple Campobello, the Canadian island where Franklin D. Roosevelt spent his boyhood summers; Patmos, with its imposing mountaintop monastery; Malekula, once the most notorious cannibal island in the world; and Jura in Scotland's Hebrides, where George Orwell wrote 1984--the island that turned Clarke into a islomane, someone Lawrence Durrell says experiences an "indescribable intoxication" at finding himself in "a little world surrounded by the sea."
Despite colonialism and missionary conversions, wartime scars and shrinking coasts, islands have thrived. Though each island is unique in its own way, Clarke discovers that the islanders themselves are a distinct people-- tranquilized by their watery horizons yet sensitive to the first shift in weather, conservative yet more likely to drop their inhibitions because no one is looking. And over every island falls the shadow of Robinson Crusoe, persuading us that islands are more liberating than confining, more contemplative than lonely, more holy than barbaric because we have been "removed from all the wickedness of the world." In a stunning work of wit, adventure, and incisive exploration, Thurston Clarke brings a unique passion to dazzling life.
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LibraryThing ReviewUser Review - untraveller - LibraryThing
Mostly a good book although some of the islands I did not really care much about. Twas a good background for Mas a Tierra, the Maldives, and the Spice Islands. Fairly well written as well. Read full review
LibraryThing ReviewUser Review - JTJonesberry - LibraryThing
Lots of unexpected surprises as the author explores a variety of locations to examine man's love affair with islands. Suggested reading for my friends undersail. Read full review
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Searching for Crusoe: A Journey Among the Last Real Islands
Thurston Clarke
No preview available - 2001
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Abemama airport Alwi American arrived ashore asked atoll Bali-ha'i Banda Neira Bandanese Barentsburg Barnhill beach beautiful become believed Bloody Mary boat boys building Campobello canoes Caribbean cars castaway Caymanian century club coast Coconut Jail coral cruise Crusoe's culture dance Dutch Eigg Eigg's father ferry fish Fishers Island French Garifuna global warming Grand Cayman Hawaii Hawaiian helicopter hundred imagine inhabitants Isla Crusoe islomania Japanese Jura Kauai Kosrae Kosraeans lagoon land lived Longyearbyen mainland Maldives Maldivian mansions McNab Michener miles mountains never ni-Vanuatu Niihau Niihauans nutmeg Octagon House palms paradise passengers Patmos perkenier Phu Quoc plantation Pleasure Spot prisoners reef remote island resort returned road Roatan Robinson Crusoe rock Roosevelt Santo Selkirk ship solitude South Pacific spent stayed story summer surrounded Svalbard told tourists trees uninhabited Utila village visitors walked walls Walung wanted


text:
Written Statement by Angel Gurría, OECD Secretary-General and J. Brian Atwood, Chair of the Development Assistance Committee to the World Bank Development Committee
Toyko, Saturday 13 October 2012
We congratulate Jim Yong Kim on his appointment as the new World Bank President and welcome the opportunity to work with him in these challenging times. We also commend the World Bank for putting some of the issues that matter most to people today on the Development Committee agenda, in particular, jobs, gender equality, and managing disaster risks.
In Busan last year, the development community agreed that the world had changed profoundly and that development co-operation needs to be based on developing country ownership, transparency and accountability, inclusive partnerships, and a focus on results. The OECD is contributing to these efforts by putting the focus on development outcomes rather than inputs and promoting an "inclusive dialogue" for growth and development, in particular by:
The OECD's Strategy for Development: an inclusive dialogue for development outcomes
The OECD's Strategy on Development is the vehicle through which we are strengthening and adapting our work on development. Building on over fifty years of development work, notably in the OECD Development Assistance Committee (DAC) and the Development Centre, the Strategy on Development provides a new impetus to our founding mission. It complements traditional development programs by strengthening the efforts to improve policy making and design in developing countries. It also builds on the accumulated experience of many of our policy communities, at the service of development.
Indeed, our development efforts reflect the need to look beyond financing and reflect a more multi-polar global economy, with emerging and developing countries playing an increasingly important role as a source of growth, finance, trade, investment, knowledge and innovation. Development is multi-dimensional and we need to adopt comprehensive approaches that cut across different policy domains and disciplines that tap into the diverse experiences and knowledge of countries, key stakeholders and policy communities, promoting an "inclusive dialogue" for growth and development.
This approach is strongly demonstrated in our work with countries to build the foundations for inclusive growth and jobs. In the fifth year of the global crisis, this work is now more important than ever. Since the crisis started, millions have lost their jobs and in developing countries millions more people have fallen into, or remained trapped in, extreme poverty. Moreover, relatively strong growth in developing economies has not sufficed to guarantee productive employment for all. For example, Africa's growth was above the global rate over the last decade but not everyone benefitted. The 2012 African Economic Outlook shows that job creation has not kept pace with population growth, and that youth have been particularly hard hit. Of Africa's unemployed, 60% are young people. Many other developing countries are confronted with a similar situation. In fragile and conflict-affected states the jobless situation is even more acute.
Strengthening engagement and knowledge sharing with developing countries to help foster inclusive, jobs-rich growth is therefore a key priority. We also need to be sure not to ignore environmental priorities. Our aim is to work in cooperation with the countries concerned and partner organisations to take a comprehensive approach to diagnosing the constraints to economic and social development in the country and help them to develop the best package of policies for their specific circumstances. This inclusive dialogue builds upon and combines existing expertise across the OECD in areas such as employment, skills, green and social policies. Key areas for developing countries to consider, as identified in the Bank's papers for this meeting, are education and skills, and gender inequality.
Investing in and making best use of education and skills is a central piece of the growth puzzle. Despite major universal gains in enrolments and participation in schooling, many young people around the world — especially the disadvantaged — are leaving school without the knowledge and skills they need to thrive in society and find decent jobs. Moreover, using data from the OECD's Programme for International Student Assessment (PISA) and other international assessments, UNESCO's latest Education For All Global Monitoring Report (2012) suggests the possibility of enormous gains in aggregate economic outcomes from improving student learning, in particular in developing countries. The OECD's PISA is an important tool that more than 70 countries are using to inform their choices of education policy and to make the best investments they can in schooling. Planning for the 2015 cycle of PISA is currently underway and a large number of developing countries that have not participated in previous PISA cycles have expressed an interest. The positive experiences of Brazil, Peru and Vietnam, for example, demonstrate that developing countries can benefit significantly from participating in PISA. PISA also has potential as an instrument to measure progress towards a global learning goal in the context of the post 2015 world.
While adequate investment in education is a pre-requisite for development, this must be complemented by opportunities for people to use their skills. Without these investments and opportunities, people languish on the margins of society, technological progress does not translate into economic growth, and countries can't compete in today's economies. This means investing in skills throughout the life cycle, not just for the time they are in school; from early childhood, through compulsory education, to the transition into the workforce and beyond. All of which contributes to economic growth and social inclusion. We are already working with MENA countries, such as Tunisia, to help tackle the pressing issue of youth unemployment.
Effectively addressing gender inequality will also deliver significant growth and jobs. Despite progress over the last century, the situation of women in many developed and developing countries remains unsatisfactory. The 2012 OECD Ministerial Council Meeting discussed the persistent gender gaps in education, employment and entrepreneurship. It focused on addressing gender inequalities to strengthen inclusive growth, reduce poverty, improve governance and encourage innovation. Ministers undertook to update and strengthen the OECD 1980 Declaration on Policies for the Employment of Women by developing a Recommendation on Gender Equality. We expect the new Recommendation to call on OECD Members to increase the gender equality focus of ODA – especially in the economic and productive sectors. In addition, one of the OECD's contributions to the UN's global thematic consultation on addressing inequalities in the post-2015 development agenda will be to gather evidence on the quality of women's work in developing countries and identify the statistical requirements for periodic and relevant measures of well-being in women's paid and unpaid work. Further, the OECD will contribute expertise on the measurement of discriminatory social institutions to better understand the underlying drivers of women's employment outcomes.
Proactively sharing our analysis and recommendations with developing countries in policy areas such as this and adapting them to their specific contexts through an inclusive dialogue is at the heart of the OECD's Strategy on Development.
Redoubling our efforts with fragile states
Our development outcomes focus also means that we are redoubling our efforts with fragile states. Working to promote growth and jobs in fragile situations presents a particular challenge. In fragile and conflict situations employment gives people a sense of self-worth and the opportunity to start shaping their future. Jobs can also reduce people's participation in violence and conflict. The challenge is to generate income opportunities fast enough, including for groups previously marginalised, former combatants and youth. The priority needs to be given to labour-intensive public and community works, increased agricultural productivity and domestic private sector development.
The OECD DAC work on peacebuilding and statebuilding, the Bank's World Development Report 2011, and a strong impetus from the UN system, have spurred the international community to prioritise and modify ways of working in fragile situations. Countries facing such situations are furthest away from achieving the Millennium Development Goals. Last year in Busan, 15 countries that have suffered from fragility and have constituted themselves in the G7+, together with 21 donor countries and 6 organisations– agreed to use the Peacebuilding and Statebuilding Goals (PSG) of the New Deal for International Engagement in Fragile States to enable progress towards the MDGs. This includes a goal on 'Economic foundations' 'to generate employment and improve livelihoods'. The focus on assessing and tracking progress in building the economic foundations embodied in the 'Economic foundations' PSG will provide valuable lessons for how to increase jobs in these situations most effectively.
Supporting developing country resilience
While the right package of policies can provide a solid foundation for growth and jobs, we also need to work with developing countries to increase their resilience to risks. Risks such as financial crises, natural disasters, food insecurity, malnutrition and disease, can prevent economies from moving forward and in many cases reverse progress already made.
We are working to identify and tackle the key obstacles that prevent a more coherent approach to analysing, understanding, preventing and responding to such risks. Some of these obstacles are related to: blockages in donor systems that separate principles and approaches to humanitarian crises from those of development assistance; decentralised versus centralised decision making; funding instruments that are inflexible in either scope, scale or time-frame; a lack of the right incentives for risk-taking and risk management and challenges of whole of government co-ordination. To date, most development actors have been risk averse and unable to see situations of risk as opportunities for change. They are so concerned about corruption and reputational risk that they fail to recognise and communicate to politicians and tax payers the need nonetheless to take certain risks.
In parallel with our work to understand the multiple facets of risk, and gain greater acceptance for risk reduction and risk management, the OECD continues to work on specific high risk areas such as climate change and food security and nutrition. Guidance developed for donors as well as partner countries on climate change adaptation emphasises issues of climate change sensitivity, adaptive capacity and vulnerability and provides a framework to increase resilience at national, local, sectoral and project levels. The OECD/DAC has also developed a means to track climate change finance for both mitigation and adaptation, the key strategy for building resilience in the face of climate risks. In relation to the risks of food insecurity and malnutrition, the OECD is working closely with the FAO and other organisations in response to a request from G20 leaders to develop the Agricultural Market Information System (AMIS) initiative and the Platform on Agricultural Risk Management (PARM), which aims to mainstream risk management in development policies in response to price volatility and food security concerns.
Building on the Busan Partnership to make development work on the ground
While each country knows its own development needs best and each international and regional organisation has its own unique expertise and knowledge to bring to the table, the global development agenda is the mortar that brings different stakeholders together to make development work on the ground.
The Global Partnership for Effective Development Co-operation agreed in Busan by 160 nations, civil society and the private sector is another very important part of the global development agenda. It represents a tangible contribution to the realisation of the MDGs as a truly inclusive partnership for development built to drive progress that provides a new political platform for bringing the "what" to achieve closer to the "how" to achieve it.
One year after Busan, the Partnership is well-positioned to demonstrate progress under the leadership of Minister Armida Alisjahnana of Indonesia, Minister Ngozi Okonjo-Iweala of Nigeria and Secretary of State Justine Greening of the United Kingdom, sustaining the political vision and consensus forged in Busan. As the different stakeholders convey their priorities and prepare for the first ministerial meeting of the Global Partnership, it will be important to draw the links with the UN-led process on a post-2015 development framework and the potential contribution that the Global Partnership can make to it.
The OECD will continue to give the Global Partnership the strongest possible support. The first priority will be to work with DAC members to deliver on some key commitments, in areas such as transparency, predictability, use of country systems, and fragmentation. On this last point, our recent report on multilateral trends found that two out of every five donor-partner country relations are not financially significant, while non-core multilateral aid continued to grow in 2010, increasing by 8% in real terms from 2009. The OECD/DAC High Level Meeting in London on 4-5 December will be the moment to demonstrate that the donor community will deliver what they promised, to empower the Global Partnership and to support the leadership by developing partners.
Strengthening our contributions to the post-2015 world, and wider global governance efforts, including G20 and G8
As the 2015 deadline approaches, all international efforts should be activated to help countries meet the MDGs. At the same time the discussion on the post-2015 agenda and framework has started under the auspices of the UN. The OECD/DAC contributed to shaping the original goals that led to the adoption of the MDGs. Today, we welcome that this will be an inclusive partner-led process and we are fully committed to supporting the UN in looking beyond the 2015 target date.
The OECD will be ready to offer its expertise in areas such as measuring the well-being of societies, supporting statistical capacities in developing and developed countries, Green Growth for development, and performance in education, which we believe can help inform solutions to some of the important challenges faced by those taking this process forward.
The OECD also continues to support the G20 Seoul Development Consensus for Shared Growth and its Multi-Year Action Plan through contributions on green growth, food security, human resource development, private investment and job creation, domestic resource mobilisation, knowledge sharing, trade, infrastructure and growth resilience. Since the launch of the G8 Deauville Partnership (DP) in May 2011, the OECD has also been actively supporting the transition countries' in the MENA region in their efforts to establish sustainable and economic growth through the promotion of job creation and good governance, including economic governance.
Official Development Assistance
Last, but by no means least, Official Development Assistance (ODA) remains crucial to development outcomes. ODA is the resource on which development partnerships are built. It is critical that it continues to be an effective, predictable and sustainable source of development financing, especially for the least developed countries. Our data earlier this year showed a 2.7 % drop in real terms in ODA compared to 2010, when ODA reached a historical peak. The fall of ODA has been a source of concern, coming at a time when developing countries have been hit by the knock-on effect of the crisis and need it most and we have continued to emphasise the importance of meeting ODA commitments. This issue and others relating to development financing will remain high on the OECD/DAC agenda in the next few years. In particular, we need to support financing scenarios for achieving the post 2015 goals and promote the use of the most appropriate mechanisms for financing development, which vary widely from one partner country to another.
In conclusion, the OECD, with the DAC and all other OECD committees and entities, is pursuing an "inclusive dialogue" for development outcomes, within the Organisation, at the national level with countries, partner organisations and other relevant stakeholders, and at the global level. Financing remains crucial, but we also need to work with countries to develop a comprehensive understanding of the policies they need to achieve growth and jobs, as well as to make them more resilient to risk. The OECD has considerable expertise on development and in inter-disciplinary public policy making. The OECD stands ready to work with all relevant partners to meet the MDGs, develop the new Post-2015 agenda, and make our Development Strategy and the Global Partnership a success.
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text: Health Information Don't Play Through the Pain: Alternative Exercises for Injured People by Christie MathesonEn Español (Spanish Version)Injuries Need to Heal | Alternative Exercises | When You Can't RunInjuries Need to Heal Nearly all injuries require recovery time, but time can be the hardest thing for an athlete to give.The key to recovery is patience. Returning to sports or activities too soon can make your injury worse. The best bet is to return to your sport only when you have been given clearance by your doctor, trainer, or physical therapist.Alternative ExercisesWith most injuries, alternative activities can allow you to rest the injured area while still getting exercise. In fact, you just might find a few new activities to love. Here are a few examples of alternative exercises for specific injuries.Ankle Injuries An ankle sprain can take you out of commission for many sports and activities. You can keep fit by doing other activities, such as rowing, that rely on the upper body and do not stress the ankle. You can also do strength training exercises like leg curls or leg extensions. Just make sure there is no stress on your ankle.Knee Injuries Knee injuries can be serious, and trying to keep going through a knee injury could make it much worse or permanent. Talk to your doctor or trainer to find out if cycling or riding a recumbent bike will make your injury worse. If not, these might be good replacement activities, because they take the weight off your legs. If your knee injury is more serious than that, consider jumping into the pool for an aerobic workout. Pulled Muscles Trying to play through a pulled muscle or tendon is tempting, because once your muscles warm up, you may not feel the injury as much. It is better to resist the temptationHamstring injuries are especially common, often caused by rapid deceleration or change of direction. If you pull a muscle, you need to let it rest. Follow RICE (rest, ice, compression, elevation) to ease symptoms.One way to work up a sweat using only upper body muscles is to toss around a medicine ball with a partner for a while. Try it for 20 or 30 minutes just tossing it back and forth, not running around at all. You'll workout using your abs and shoulder muscles.Achilles Tendinopathy An aching Achilles tendon has been the downfall of many athletes. So, if you feel pain, do not ignore it. Take a break from all sports that make it worse, especially running or activities that involve running. Using a rowing machine is a good way to stay fit while resting your Achilles tendon. You may be able to use an elliptical trainer as well. Tennis Elbow Players of racquet sports are familiar with elbow pain. If a case of tennis elbow starts to interfere with your game, take time off to let the injury heal. You can keep running and doing interval training, including plenty of short bursts of speed and side-to-side movements to stay in top tennis shape. Shoulder Injuries Hurting your shoulder can interfere with your ability to participate in a host of popular recreational sports. You do not want to serve, swim, swing, or throw with a shoulder injury. With particularly painful shoulder injuries, even the arm-swinging inherent to running can be too much to take. Avoid overhead movements and any arm position that causes pain. And make sure you get professional guidance before picking up a racquet or swimming again. Do as much lower-body weight training as you can handle. Try running, cycling, stair climbing, and even rowing. When You Can't RunRunning is the foundation of many fitness programs, because it produces such effective cardiovascular results. But it is also an activity that is likely to be hampered by a sports injury. It's impossible to mimic the effects of running, but you can come close by using a stair climber or elliptical trainer. Circuit training also helps runners who are taking time off the road. Have 10 or 12 weight machines that you want to use, and go through them in a regular pattern. Do one set on each machine with light to moderate weight—less weight than you would usually use. There are many more safe and effective exercises you can do when injured. You may need to try a number of them to find the right one. Working with a physical therapist or personal trainer may help.RESOURCES:American College of Sports Medicinehttp://www.acsm.orgNational Strength and Conditioning Associationhttps://www.nsca.comCANADIAN RESOURCES:Canadian Society for Exercise Physiologyhttp://www.csep.caHealth Canadahttp://www.hc-sc.gc.caReferences:Basic knee injury prevention. American College of Sports Medicine website. Available at: http://www.acsm.org/public-information/articles/2016/10/07/basic-knee-injury-prevention. Accessed April 18, 2017.Resistance training and injury prevention. American College of Sports Medicine website. Available at: http://www.acsm.org/docs/current-comments/rtandip.pdf. Accessed April 18, 2017. Return to play. Ortho Info—American Academy of Orthopaedic Surgeons website. Available at: http://orthoinfo.aaos.org/topic.cfm?topic=A00365. Updated August 2007. Accessed April 18, 2017.Return to play—a coach's guide. American College of Sports Medicine website. Available at: https://www.acsm.org/docs/brochures/return-to-play----a-coach's-guide.pdf. Accessed April 18, 2017.Sports injuries. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: https://www.niams.nih.gov/Health_Info/Sports_Injuries. Updated February 2016. Accessed April 18, 2017.Last reviewed April 2017 by Michael Woods, MD, FAAPPlease be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © EBSCO Publishing. All rights reserved.Editorial PolicyPrivacy PolicyTerms and ConditionsSupport


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Love brings hope to Next Act Theatre's 'Grace'
When the lights come up on Craig Wright's "Grace" - now at Next Act Theatre, under David Cecsarini's direction - a man is holding a gun to his head, having just murdered the woman and man sprawled nearby. We can guess what happened with this love triangle. But how? And why?
With the whodunit out of the way, "Grace" tries to answer those questions by taking us back three months and starting over. During the ensuing two hours, we'll move forward in time toward that climactic scene with which the play began.
What a difference those three months make. Steve (Rick Pendzich) - the gun-toting soul from the first scene - is now an evangelical who has been promised the millions he needs to launch a hotel chain focused on traveling Christians.
Sara (Libby Amato), his young and beautiful wife, can hardly believe the good news - fair enough, given its magnitude, but also our first sign of trouble in paradise.
Amato, who does excellent work here, helps us see that Sara's surprise - as well as her dutiful smiles and good cheer - mask growing doubt and resentment, regarding a man proving to be less than she'd imagined. Call it a spiritual crisis, in a play that's all about how hard it can be to keep faith - with religion, others and oneself.
The self-involved and smarmy Steve would test anyone's belief system. Changes from the published script take an already flat-edged caricature and make him even less credible, and it's no reflection on Pendzich - who plays him broadly, as an over-the-top televangelist - that we have a hard time taking Steve seriously.
Ditto much of Wright's flimsy plotting, which gives an improbable account of Steve's fall from financial grace. Wright also relies heavily on very bad things that happened before the time of the play to flesh out the remaining two characters, and explain why they're not as chummy with God as Steve thinks he is.
Karl (John Kishline), a darkly humorous bug exterminator who lived through unspeakable horrors as a child, is an avowed atheist. Sam(Jonathan Wainwright), a computer wizard who lost his fiancée and his looks in a car accident, doesn't think about God at all.
Sam is also Sara's next-door neighbor in the Florida condominium complex where she and Steve live. While Steve is out hustling for dollars - and undergoing his own crisis of faith as his envisioned riches evaporate - Sara and Sam are drawing closer.
Even as "Grace" unfolds on a set where two identical condos are superimposed on one playing space, Sam wistfully comments that we can't defeat time and collapse the space that therefore divides us.
But the scenes between Sara and Sam - with Amato and Wainwright vividly conveying how lonely, vulnerable, afraid and yet hopeful these characters are - suggest otherwise, providing a loving alternative to more sectarian views of just how amazing grace can be.
"Grace" continues through April 28 at Next Act Theatre, 255 S. Water St. For tickets, call (414) 278-0765 or go to www.nextact.org.
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