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Welcome to the Real Salt Lake Youth Soccer Update. This regular release will include information on matches, tournaments, events and achievements involving RSL's youth initiatives.
RSL-AZ U-18's REMAIN UNDEFEATED AFTER SUCCESSFUL WEEKEND IN SO-CAL
The Real Salt Lake-Arizona Academy U-18's kept their unbeaten record intact their last time out, picking up a win and a draw against a pair of Southern California rivals.
The U-18's drew their first match, tying Irvine Strikers FC 3-3 in Southern California on Saturday, Nov. 3. The team picked up a win the next day, getting a goal at the death to beat Pateadores FC 2-1 on Sunday, Nov. 4.
FW Jose Navarro was the star for the U-18's, scoring four goals – including a first half hat trick against Irvine – in the two matches to move his season total to seven. MF Riggs Lennon also played well, picking up two assists to help the U-18's stay unbeaten.
The U-18's are now 6-0-2 in the U.S. Soccer Developmental Academy season, good enough for first place in the West Conference's Southwest Division.
RSL-AZ U-16's PICK UP TWO WINS, MOVE TO 6-0-2 ON THE USSDA SEASON
The Real Salt Lake-Arizona Academy U-16's picked up two wins two weekends ago, downing Irvine Strikers FC and Pateadores FC to improve to 6-0-2 on the USSDA season.
RSL-AZ turned in a dominating performance in its first game, downing Irvine 4-1 on Saturday, Nov. 3. The U-16's picked up another win on Sunday, Nov. 4, beating Pateadores 2-1 to cap a six-point weekend.
FW Sebastian Saucedo and Damian German were the stars for the U-16's, with Saucedo scoring a goal and adding two assists and German notching a pair of goals.
Like their U-18 counterparts, the U-16's are now 6-0-2 in the Developmental Academy season. The squad sits in first-place in the West Conference's Southwest Division, holding a comfortable six-point lead on second-place Chivas USA.
The Real Salt Lake-Arizona U-18's and U-16's return to USSDA action this weekend, when they'll take on fierce rival LA Galaxy at Grande Sports World in Casa Grande, Ariz. on Saturday, Nov. 17.
The Galaxy U-18's are nipping at the heels of the RSL-AZ U-18's, with LA – which has two games in hand on RSL – sitting four points behind the Claret-and-Cobalt in the standings. The RSL-AZ U-16's are 12 points up on the fourth-place U-16 Galaxy, which also has two games in hand on their RSL-AZ counterparts.
The U.S Soccer Development Academy is a nationwide youth development initiative, organized by the U.S. Soccer Federation, featuring 80 of the top youth teams in the country competing in a league system at both the U-18 and U-16 levels. The 80 youth programs are divided into 7 geographically based divisions, each of which will send a single qualifier to the national finals after the regular season concludes in late June. For more information on the U.S. Soccer Developmental Academy, please visit www.ussoccer.com.
For media information about the Real Salt Lake Youth Development program, or any other RSL activities, please contact Real Salt Lake Media Services Manager, Sam Stejskal at firstname.lastname@example.com or at (801) 918-5050.


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CASE50313: Horary consultation concerning Mrs Frances Conny (PERSON29239)
Question asked by Matthias Conny (PERSON19343) on 24 February 1620 at 10:15
RW Mr Matthias Cōny of Newport for his daughter Francis. y. 4. d ♃. h: 10: 30 \15/. ant: m Feb: 24. 1620. eateth nothinge: is verie faynt & weake./ had a little of diaprunis wch brought away ij wormes.
[Astrological Chart]
Transcribed entry from MS Ashmole 213, f. 137r (upper centre part of page)

subset: commoncrawl


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I am currently trying to run a Superlab 4.5 program that was created on a Mac on windows.
I am aware of the typical change in font that can be easily corrected, however, I am having issues with the macro code.
For instance, the participant get 8 responses correct consecutively in order to move on to the next level of difficulty in this specific task OR if they cannot do this there is a time out function of 5 minutes in which they will automatically be moved onto the next level of difficulty.
I have tried to complete the task several times, and it appears to move onto the next difficulty level randomly. I have compared the macros on my computer(windows) and on my colleagues computer who made the program (mac) and they seem to be identical.
Has anyone experienced this sort of issue before or know about how to fix it?


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Calendar | Community
| Family & Friends in the Armed Forces
| Milestones
Community Action |
Humane Society | YMCA
Honor Flight No. 28 scheduled for
August 26
Send a link to a friend
[August 25, 2014]
Tuesday, August 26th, the Land of Lincoln Honor Flight (LLHF) hub
from Springfield, Illinois, will take their first flight since
folding in the now defunct Central Illinois Honor Flight into their
territory and blending their two waiting lists, based upon the date
of applications from Veterans.
Now serving central and southern Illinois, this Flight #28 will
have 80 Veterans aboard – 32 from World War II, 43 from the Korean
War era, and 5 of the Vietnam War era. On this no-cost, day long
tour to Washington, DC, to visit and reflect at their national
memorials, each Veteran will be accompanied by a volunteer Guardian
escort who pay their own way and are responsible for the comfort,
logistics, mobility and safety of their Veteran(s) for the day.
Aboard the chartered 737 aircraft will be Veterans from the US Air
Force, Army, Marines and Navy branches, as well as from the Merchant
Marines and Army Air Corps from WW II.
After landing at Ronald Reagan National Airport in DC, they will be
transported for the day on three tour buses (code name Red, White
and Blue) with an itinerary including stops at the World War II
Memorial, Korean Memorial, Vietnam Memorial, National Air & Space
Museum (Chantilly, Virginia), Air Force & Marine Corps Memorials,
Pentagon drive-by and concluding at Arlington National Cemetery,
including the Tomb of the Unknown Soldiers and Changing of the
Guard. They will also have the opportunity to visit the Lincoln
Memorial, as well as see the Washington Monument, Jefferson
Memorial, DC World War I Memorial, and much more.
Veterans on this flight come from the Illinois cities of Altamont,
Argenta, Bonnie, Carmi, Centralia, Cerro Gordo, Charleston,
Collinsville, Danville, Decatur, DuQuoin, Edwardsville, Effingham,
Gays, Harrisburg, Havana, Highland, Hoopeston, Loami, Mattoon, Mt.
Zion, Mulkeytown, Murphysboro, Neoga, Olney, Oreana, Savoy, Scheller,
Shelbyville, Sigel, Simpson, Springfield, Stewardson, Streator,
Tallula, Teutopolis, Urbana, Walnut Hill, Warrensburg, Watseka,
Wayne City, West Salem and Yale, as well as Evansville, Indiana.
[to top of second column]
The public is invited and encouraged to show their
appreciation for these Veterans by welcoming them home when they
return to Springfield's Abraham Lincoln Capital Airport on
August 26th, arriving at approximately 9:30 PM. It is suggested
to be to the airport by 8:30 and feel free to wear red, white &
blue to show your patriotic spirit or bring small American
flags, balloons, posters, etc.
Land of Lincoln Honor Flight
also announces that the flights for the balance of the year have
been confirmed for September 16th and October 28th and are now
filled. However, Veteran applications continue to be accepted for
the 2015 flight season, with priority given in the following order:
World War II ~ a soldier enlisted by 12/31/1946
Korean War Era ~ 01/01/1947 to 12/31/1957
Vietnam War Era ~ 01/01/1958 to 05/07/1975
Land of Lincoln Honor Flight is a 501(c)3 non-profit organization,
receiving no federal, state or county funding. The donations,
sponsorships, fund raising and efforts of many individuals and
businesses have allowed LLHF to honor this flight of Veterans. For
more information on speaking to organizations, how to obtain an
application, make a donation or just learn more about the Honor
Flight mission, please visit the official web site at
LandofLincolnHonorFlight.org or contact John Dust, marketing/media
director, at email@example.com or cell 309-339-0227.
[Text received; LAND OF LINCOLN HONOR
Back to top


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The movement is growing, we have seen it in the number of people coming to this website, the number of houses being built and if you haven't checked out the Tiny House Map, you should and be sure to add yourself! I came across this great video of some tiny houses and the people who live in them.
Your Turn!
- Are you planning on building your Tiny House yourself or have someone build it for you?


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Psoriatic arthritis is a form of arthritis that sometimes develops
in people who have a skin condition called psoriasis. It causes swelling and
pain in joints—most often in the fingers and toes—in an irregular pattern that
may be different on opposite sides of the body.
Treatment for psoriatic arthritis includes pain medicine, patient
education, and physical and occupational therapy. Severe cases may require more
powerful medicine called biologic drugs or steroid injections.
Last Revised:
January 9, 2012
Healthwise Staff
Medical Review:
Adam Husney, MD - Family Medicine & Amy McMichael, MD - Dermatology
This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.
To learn more visit Healthwise.org
© 1995-2012 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.


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A few months ago I asked Jon Brassey of Tripdatabase, a clinical search engine or metasearch, if he could ask patient decision aids to the database. Patient decision aids (PDAs) are tools that are made with the aim of helping patients make decisions about treatment options through considering the risks and benefits of options. They are produced by the UK National Prescribing Centre (NPC) and NHS Direct, amongst others. The advantage of having them listed in a metasearch is that I don't have to go round several sites checking if they might have a decision aid on the topic I am interested in.
Tripdatabase is a small but dynamic organisation and it makes great use of social media. Jon uses a Facebook page to get feedback from users, and I was able to give him my suggestion my sending him a tweet. You can see how quickly he responded here, but the short version is that in less than 3 weeks PDAs were added to Trip!
I've recorded the following screencast to show how I used Tripdatabase to share decison making with a patient. In this case the decision to start warfarin to reduce the risks of stroke in atrial fibrillation had been made in secondary care but we were able to review the evidence for this together. We also used the NPC patient decision aid to review the risks and benefits of warfarin treatment.
As you can see the NPC decision aid is not perfect. I don't think that a PDF is the ideal format for exploring this information online. And I don't have access to a colour printer in the surgery so if printing it might be good to have the option to print a version that was not so dependent on colour graphics.
Have you any thoughts on how PDAs can be incorporated into consultations? Please leave a comment!
EDIT 7/2/2012 As I mention in the audio here I explicitly asked this patient's consent to share this story.
EDIT 7/12/2015 Key learning for me in this was that the patient had different concerns to that which I assumed they had. I thought they were worried about inconvenience of warfarin (for given benefit), but they were actually concerned about risk of harm. The decision aid reassured them about risk of harm.
Tuesday, 22 November 2011
Saturday, 5 November 2011
On being public : How social media reshapes professional identity.
This was my presentation at ALT-C (conference of the Association for Learning Technology) earlier this year. It sums up in 20 minutes a lot of the thoughts and ideas that are covered in this blog. But of course it raises more questions than answers- I hope!
Subscribe to: Posts (Atom)


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Written By: NM State Athletic Dept.
LAS CRUCES, N.M. - The Green Bay Packers announced Tuesday the Signing of former New Mexico State defensive end Donte Savage. Savage is listed as a linebacker with the Packers. The transaction was announced by Ted Thompson, Executive Vice President, General Manager and Director of Football Operations.
Savage participated in the team's rookie orientation camp this past weekend on a tryout basis. Savage played in all 12 games at defensive end for the Aggies in 2012 and led the defensive line with 45 tackles, including seven tackles for loss, three sacks, four QB hurries, two blocked kicks, a fumble recovery and a pass defensed. As a sophomore in 2009, he registered 53 tackles, including 12 tackles for loss, six sacks, two forced fumbles, two fumble recoveries, two passes defensed and a blocked punt.
Savage is the third NM State football player this off season to sign with an NFL, following Jeremy Harris, who was drafted by the Jacksonville Jaguars in the seventh round of the NFL draft and wide receiver Kemonte Bateman, who signed as a free agent with the Denver Broncos. Savage joins former Aggie defensive back Davon House on the Packers' roster.


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When is the next solar storm expected? What effects could you expect? On that note, how far away from the Sun does a solar flare shoot?
Solar storms (which usually include flares) are associated with high numbers of sunspots. The next sunspot maximum will occur sometime in the years 2000 or 2001. So the next solar storms are predicted to occ ur during this time period.
The solar flares which are produced during solar storms could produce drastic effects here on Earth. These solar flares, which arch about 400,000 kilometers above the Sun, produce an increase in the number of charged particles which enter the Earth's at mosphere. This can disrupt long-distance radio communications. It also makes the aurorae (the Northern and Southern lights) brighter. So in the next few years, if you see an aurora where you've never seen it before , it is might just be caused by a solar storm!
The image shows how big a solar flare is compared to the size of the Earth!
Submitted by Johan (South Africa)
Submitted by Elliot (England)
(September 17, 1997)


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Collier bague pneu ANS *BRONZE*
Necklace ANS tire ring *BRONZE*
These rings are inspired by the all-time classic 'All Non-Skid' and 'Deluxe Champion' motorcycle tires. Icons of the great era of the automobile in North America, these tires created at the beginning of the XXth century are still produced nowadays and thus remain timeless values.
Available in silver or bronze, the rings are handmade in France according to an original cast.
- The rings are made from bronze
- Cross tread pattern
- Size of the ring : Thickness 3,5 mm, width 6 mm
- The ring can be removed from the bracelet and worn on its own
- Available in two sizes (inside diameter is 21,5 mm and the other one is 19,8 mm)
- UK size Y and T 1/2
- US size 12 and 10
- Italy size 27 and 22
- Japan size 25 and 20
The measurement with a downloaded ring size chart is not very accurate; the easiest and most accurate way to determine your ring size is to have your finger measured by a jeweler.
N.B. If you have a smaller finger size, it is possible to reduce the size of the ring. Ask your local jeweler. For a larger finger size, it is not possible to enlarge the rings.
Over time, silver and brass will tarnish. It is a natural process that cannot be prevented but it can be slowed down (avoid water, chemicals).
Use a shammy and special silver-care polishes to maintain your jewelry.
Pictures and design © Sankakel
Photos © Götz Göppert gotzgoppert.com
Registered design
Livraison France
EU delivery
World delivery
Masque denim 'Menpo' (avec filtre) *NOIR*
"Menpo" denim mask (with filter) *BLACK*
Masque denim 'Menpo' (avec filtre) *BLEU*
"Menpo" denim mask (with filter) *BLUE*
Pochon de rangement
Drawcord bag
Masque herringbone marron
Mask herringbone brown


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I have a son who is a genius. The day Chuck was born I knew it for a fact. Didn't he say, simplex munditis at 10 months? The first phrase he ever spoke was not in mother tongue as though he sensed he was making history of sorts.
The occasion was simple though. He lay in his crib and between drinking his constitutional and wetting the bed he had freed himself from his blankets. When his mother picked him up and wanted to tuck him back he just backed off to say, 'elegant in simplicity'. His dimpled smile was right and his baby fat made him a dumpling. Later it seemed to me he didn't have the patience to say the old blankets chafed him and in his birthday suit he felt great and like a brick of gold. Naturally he had to express his joy at being comfortable with a quote from Horace. Horace, no less!
At the age of four Juvenal and Goethe were jockeying for a spot in his intellectual firmament. Before he hit the five he knew Nietzsche was speaking his own lingo.
While his mother and I went from speculation to handouts.
Chuck was getting ahead till he had a title that was impressive. His bonus was phenomenal that spoke volumes than speaking 10 languages like a native.
One comfort we had in the cash strapped times was that dialects of the world were not in the immediate danger of extinction. From South America to Fiji our son Chuck had collected them all just in case.
One week end he dropped in to see us. He said he liked what he saw about us. Next thing he wanted to move in with us.
Before I could ask what was the idea he hinted the company was downsizing so he was on transition.
I was incredulous. I asked, 'Son what with all your education?'
He was over educated he said and it was working against him. He shrugged and said, 'Never mind Pop, I will find a way to brand my over-achievement into edutainment space.'
After fixing himself a sandwich he added: 'meanwhile garbage is piling up on my elbow'. ( Later it struck me garbage was his pile of resumes returned unread.)
He was somewhat moody that he had not the bandwidth besides his language skills.
He said, 'Employers don't want to wrap around their heads but park their behinds on shmucks who do not know their onions.
It was then I realized Chuck was a genius to his own hurt. I ought to have known: since the time he quoted from Horace by a spark of inspiration he was heading for disaster.
I gently patted him on his back and said ' Courage, son. You opened your life with such a stirring phrase far remarkable than Longfellow's Excelsior. You quoted simplex munditis, unaided. I am certain Horace was at your bedside.'
My son's eyes sparkled and faded. With downcast eyes he muttered, 'semel insanivimus omnes'*( We all have played fool once.)
Yes Chuck was right. He had played the fool to rely on his superior intelligence; just as his mother and I had warmed in our knowledge his genius was of a superior mode. The trouble was that the world only needed one with just enough skills to prove he wasn't a moron.


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JACKSONVILLE, Fla. – Education Commissioner Tony Bennett is mulling a reorganization of the state Department of Education, but the project has been slowed by laws that spell out the responsibilities of some positions at the agency.
It's not clear how wide-ranging Bennett's plans for the department are, in part because the commissioner admitted to being surprised by the legal hurdles to overhauling the agency. But Bennett wants the State Board of Education to sign off on the plan at its September meeting, clearing the way for the changes to begin by October or November.
It would put the new commissioner's mark on the department as he looks to implement goals like the "90-60-90-90" plan, which calls for 90 percent of students to test at grade level, 60 percent of students to gain college credit from Advanced Placement or other courses or get an industry certification, 90 percent to graduate from high school in four years and 90 percent to be successful in college or a career after they leave.
Bennett told members of the board during a meeting in Jacksonivlle on Tuesday that his goals for the agency were to prepare the department to implement the nationwide "Common Core" standards for schools and the state's performance-pay law, in addition to the "90-60-90-90" targets.
He also suggested the agency that emerges could be leaner.
"The more we can shift resources to drive dollars to schools and to classrooms, the better we are," he said. "And that is really my focus here."
One problem has already cropped up and complicated Bennett's initial plans.
"One of the things I didn't realize when I came here was that we have a lot of positions in the Florida Department of Education that are outlined in statute," said Bennett, who came to Florida from Indiana.
For example, Bennett said, positions that include deputy commissioners and chancellors are part of the law, as are some of those positions' responsibilities. That could limit his ability to shake up the organization of the agency, at least in the short term.
Some board members, though, questioned whether that should be an obstacle. Instead, board member John Padget said, the department should ask the Legislature to change the law if necessary.
"I don't think that we should take an existing statute as a barrier," Padget said.
Bennett said he wants to try to get at least some of the reorganization done before the legislative session.
At least one board member voiced caution about the possibility that the plans could become a distraction, particularly with the state facing the tall task of getting the Common Core standards into place in the face of some public resistance.
"Tallahassee's a small town," said board member Kathleen Shanahan. "And reorganization is a big word, because people's lives are impacted."


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Postcodes PE, NR, CB, IP, SS, WC, E, EC, IG, RM, SG, CM, CO, AL
Use this control to limit the display of threads to those newer than the specified time frame.
Allows you to choose the data by which the thread list will be sorted.
Order threads in...
Note: when sorting by date, 'descending order' will show the newest results first.


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I'm not exactly proud about this one in many regards (security, for instance) by was actually something needed by a relative that, from time to time, go to some random shop to print PDFs. Having to put them on a device like a USB Key or hard disk is some kind of a nuisance, especially when your own workstation is behind a static IP.
The way it works is that it asks you for a password. If you have none, then it'll send you a random one by mail. This password will be erased after an hour.
Security notes: this could be subject to packet sniffing so I don't suggest to use it as it is for any sensitive data. It can easily be improved in regards of security depending on the end user you're targetting, in my case it had to remain as basic as possible. It logs everything so fail2ban and other tools can easily be set in motion.
It's composed a perl script, a cronjob and a nginx example config file. The perl script will ask the user for a valid user name and set up the temporary access accordingly. The cronjob will be used to reset passwords. The sample nginx shows how to run the perl script as appropriate error page and provided access either by basic auth or IP.
Install guide from the README :
1) It assumes your nginx supports perl like in
apt-get install nginx libfcgi-perl wget wget http://nginxlibrary.com/downloads/perl-fcgi/fastcgi-wrapper -O /usr/bin/fastcgi-wrapper.pl wget http://nginxlibrary.com/downloads/perl-fcgi/perl-fcgi -O /etc/init.d/perl-fcgi chmod +x /usr/bin/fastcgi-wrapper.pl chmod +x /etc/init.d/perl-fcgi update-rc.d perl-fcgi defaults insserv perl-fcgi
2) Copy and edit the nginx sample and crontab sample into the appropriate places:
– something like /etc/nginx/site-available/transit symlinked to /etc/nginx/site-enabled
– /etc/cron.d/transit
3) Then you must create a group named transit and add to it users that
are entitled to use this.
4) You must also make sure nginx (www-data?) can write to the directory where
you store the .passwd file. In the default case here, it's /etc/nginx/passwd/


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This is from the Direct Marketing Association website.
At MTAC yesterday, Tom Foti, USPS Marketing Manager described the 2010 Summer Sale. The sale will cover a 5-month period with the sale period starting July 1 thru Sept 30. June and October will be control months. A 30 percent rebate on incremental volume will be offered above a baseline. The sale is for Standard Mail letters and flats only. The customer's baseline will equal Same Period Last Year (SPLY) numbers plus 5 percent. A downward adjustment will occur if June and October volume is below baseline. To be eligible, a customer has mailed over 360K Standard Mail pieces from July 1 thru Sept 30 2009. According to Foti, there are approximately 3,525 customers eligible or 67 percent of Standard Mail volume. Mail Service Providers are not eligible to participate.
USPS Timeline:
File notice with PRC (late Feb)
Invitation to participate mailed (early Mar)
Customers register online and certify agreement with threshold volume on-line for program participation (Mar-May)
PRC decision (mid-April)
Sale period (July through Sept)
Rebates to customer accts (Dec 2010- Jan 2011)


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Sporting Kansas City 0, Real Salt Lake 0 | MLS Match Recap
KANSAS CITY, Kan. – Even without Nick Rimando, Real Salt Lake had another spectacular night of keeping the ball out of their own goal.
Putting it in at the other end, even with a man advantage down the stretch, didn't go so well for the Claret-and-Cobalt on Saturday night, as they played to a scoreless draw with Sporting Kansas City at Sporting Park in the rematch of last year's MLS Cup Final.
Jeff Attinella, starting in goal for the injured Rimando, had a nine-save blinder of a game. But Real (2-0-3) managed only four shots at the other end and only one of those was on goal, giving Sporting goalkeeper Eric Kronberg an easy time of his second clean sheet for Sporting (2-1-2).
Kansas City, which had 20 shots on the night, had to play a man down after defensive midfielder Uri Rosell was sent off in the 83rd minute for a tackle on Devon Sandoval.
Attinella's best work came in the first half, when his four saves included a sprawling parry of Benny Feilhaber's rocket from distance in the 34th minute. He also stoned Dom Dwyer on a 1-v-1 in the 11th, after the forward slipped behind the back line to take a ball over the top from Matt Besler, and saved Seth Sinovic's short-corner blast over the bar in the 27th.
And the one time he got caught out in the second half, the woodwork and defender Nat Borchers bailed him out.
Dwyer got around Attinella on the right wing in the 63rd minute, but his low shot from a tight angle hit the outside of the near post. The ball rebounded to Sal Zizzo with Attinella in no position to make the save, but Borchers blocked Zizzo's shot in the box.
Sporting's last chance to win it came deep in second-half stoppage time, but Attinella was able to get down to stop Zusi from putting a shot just inside his right post.
Rimando and defender Tony Beltran did not travel after picking up knocks in the United States' 2-2 draw with Mexico on Wednesday, but Salt Lake kept Kyle Beckerman in his usual spot at the back of their diamond midfield. Winger Graham Zusi and center back Matt Besler, both starters for the U.S. on Wednesday, were in Sporting's XI as well.
Right back Chance Myers made his first appearance of the year for Sporting, completing his recovery from a preseason groin strain by going the full 90 on Saturday. Spanish winger Toni Dovale made his MLS debut as a 79th-minute sub for Zizzo.
Real are on the road again next Saturday, taking on Philadelphia at PPL Park, while Sporting are idle until they host Montreal on April 19.
MLSsoccer.com Men of the Match
|What We Saw
|Jeff Attinella
|No Nick Rimando, no problem. Attinella set the tone for the draw with an impressive first half that included several highlight-reel saves.
|Chris Schuler
|Held firm and was aggressive vs. Sporting KC's attackers, especially in the second half when the hosts sent waves of attacks at RSL's back line.
|Graham Zusi
|Kicked things into another gear after halftime and was involved in several dangerous scoring chances. He agonizingly missed wide on an early second-half chance.
Steve Brisendine covers Sporting Kansas City for MLSsoccer.com.


text:
New features recently added to pBiblx2 make it easy to incorperate a number of Field Wise components into your own html web pages.
- As of 11/27/2010 these features include:
- a basic bible search dialog X=d
- a basic bible content dialog X=c
- a combo bible search/content dialog X=x
These can be inserted into your html code via iframe or framed with or without you hosting a pBiblx2 server.
Some preliminary examples are included:
Various CSS techniques are now being tested to tie page styles together.
( Return to parent thread PbiblxHelp )


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Protein is made of
building blocks called
amino acids. Although the human body can make some of
these amino acids, nine of them (the essential amino acids) must be obtained
from food. Soy foods and animal sources of protein (milk, eggs, meat, poultry,
fish, and seafood) contain all the essential amino acids in the amounts our
bodies need.
Most plant foods contain some of the essential amino acids in
varying amounts. Beans have some amino acids, and grains have other amino acids. Eating these different types of food throughout the day will provide your body with adequate protein. They complement each other to form a whole protein.
Complementary proteins
Foods that contain protein
Next Section:
Previous Section:
Last Revised:
November 3, 2011
Healthwise Staff
Medical Review:
Sarah Marshall, MD - Family Medicine & Rhonda O'Brien, MS, RD, CDE - Certified Diabetes Educator
This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.
To learn more visit Healthwise.org
© 1995-2012 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.


text:
Celebrating illustration, design, cartoon and comic art of the mid-20th century.
Friday, June 05, 2009
Canada's Forgotten Cartoonists: Duncan MacPherson, Bert Grassick
I hadn't really intended to include MacPherson in this week's series because I don't consider him a "forgotten cartoonist"...
His entry in the Canadian Encyclopedia tells us MacPherson was "regarded as having been one of Canada's best political cartoonists, Macpherson received the ORDER OF CANADA, the Royal Academy Medal, The CANADA COUNCIL's Molson Prize and six National Newspaper awards for his work at the Toronto Star."
I have wanted to show you these beautiful drawings by MacPherson (so reminiscent of the work of one of my favourite illustrators, Robert McCloskey) for a very long time. So Jeff's request gives me an excuse to do that this week.
And though MacPherson is probably not forgotten by Canadians, I suspect this tremendously talented cartoonist is unknown by readers from other countries.
What might be forgotten is some of the interesting techniques the young MacPherson experimented with in his early days...
... before settling into the more typical inked line style that one expects to see from an editorial cartoonist. Here's an early example of what would eventually become his well known intricately detailed ink drawing.
As this brief note from 1951 mentions, MacPherson burst on the scene at Maclean's right out of art college - but the then 27-year-old artist had been working professionally for several years while simultaneously attending school.
Sharing MacPherson's designation as an editorial cartoonist (as well as being a fellow regular contributor to MacLean's) - but far more likely to qualify as "forgotten" - is Bert Grassik.
Grassick's work had a very direct, energetic quality that I think will be much appreciated by my fellow "ink studs" - his lines look like he attacked the page with gusto! Grassick had an admirable ability to say a lot with relatively little in the way of finicky detail.
This kind of 'visual shorthand' is sometimes dismissed as simple or easy... but it takes tremendous skill and understanding of both your subject matter and your drawing equipment to do what Bert Grassick did. He managed to make it look effortless.
"Charles Albert Grassick was born in 1909 in Victoria, B.C. and soon after moved to Winnipeg, Manitoba where he grew up with his three brothers. When Grassik was 13, his father died, and the boy was forced to quit school and go to work to help support his family. In spite of numerous cartooning awards from the Winnipeg Tribune for his submissions it was felt that he should provide for the family while his older brother was sent to art school."
"Due to years of noisy factory work he became hearing impaired in both ears causing him to become isolated, quiet and reserved."
"At the age of 20 (1929) he hopped a freight train to Toronto to seek his fortune and was hired on first at Rabjohn Enterprises, then at Clement Saila & Co. as an illustrator."
"By the beginning of the 1950's his recognition gained him a position as the daily political cartoonist for the Toronto Telegram where he remained throughout the decade (1959). He had a short foray into the new frontier of television as the caricaturist for a game show on CBC entitled "Whozit" where a guest panel was given verbal clues while he sketched visual ones until someone guessed the right answer. However it was short lived and not to his introverted liking."
"His often award winning cartoons garnered attention from many sources including that of Mayor Nathan Phillips. He then proceeded to join the Disney team at Canaline (again with Clem Saila) where he remained until the age of 73."
"He also freelanced cartoons regularly for MacLean's Magazine and several other publications throughout his career and taught cartooning at the Ontario College of Art. Bert Grassick died in 1998 at the age of 89."
* Here I must thank my friend, Jaleen Grove, for undertaking the Herculean task of putting together The Index of Canadian Illustrators wiki . If not for Jaleen's efforts, I would have only been able to tell you the above cartoons were done by "someone named Grassik". The biographical information above is taken from Bert Grassik's entry on Jaleen's site.
Of course there were plenty of other Canadian cartoonists who we have (mostly) forgotten... but they will have to wait for another occasion. For now, we're done with this topic.
24 comments:
Beautiful work here, especially enjoy Grassick, who reminds me of both Patterson and Harry Devlin. Great bold inking.ReplyDelete
I would add that Duncan MacPherson's political cartoons were the best we've ever had, in terms of drawing style (he was edging toward being Canada's Mort Drucker, IMO) and perceptive wit in his subject matter. He struck me as the most literate cartoonist we've ever had.ReplyDelete
Shane and Black Pete;ReplyDelete
Thank you both for your comments and insight!
I was also reminded of Russell Patterson when I saw Grassik's work - but I'm not that familiar with Harry Devlin... will have to do a little research on him. As weird as this may sound, Grassik's inking and character construction reminds me a little of one of the cartoonists who drew Sad Sack comics for Harvey... does anyone else see that?
Regarding MacPherson, I never really followed his editorial cartooning very closely. I always saw the collections at the library, but tended to avoid them as a kid because of the impenetrable (for a kid) political subject matter. Later, when I was old enough to appreciate that sort of stuff, I preferred the work of my hometown paper's (The Hamilton Spectator) editorial cartoonist, "Blaine" - who was cut more from the cloth of the bold inkers like Grassik than the detailed 'engraving stylists' like MacPherson. But both you and Jeff have nothing but praise for DM, so I will bow to your authority on this one :^)
haha... "... unless you're embroiled in a debate on David Apatoff's blog!"ReplyDelete
I should emphasize that I completely fell in love with MacPherson's early work shown in this post - so unexpected when my only (passing) exposure to him was those collections at the library all those years ago. Does anyone know if these early variations of style were ever continued by DM?
What I really take away from seeing these ( esp. the 'School Days' drawings, is what a natural draughstman he was... his abilty to give the people in his drawings "weight" and movement... similar to Frank Frazetta's uncanny natural ability, if you see what I mean.
Truly a remarkable talent!
Thanks for the Duncan Macpherson images! He was sort of the reason that I got into art in the first place. I was so taken by his work when he worked for the Star and I remember watching on tv an NFB film on the history of political and editorial cartooning in Canada called "The Hecklers" that I decided to pursue art. I think that I was 16 at the time and I was into B&W editorial cartoons! Great way to get girls, eh?ReplyDelete
Did I ever tell you that I used to work with his son, Ian, when I taught at Central Tech here in Toronto?
I remember an art school event one night at Metro Hall, sort of a gala night showing the work of alumnis and former teachers at CT, Duncan was an alumnis and there were some of his work on display, and Ian brought his mother, Duncan's widow, and was nice enough to introduce me to her and I told her what an influence Duncan's work had on me. She was very flattered that Duncan's work had that much of an effect on me.
Right on, Leif! After one go-round with David, I've decided to avoid his Comments section like the plague. But I learn a great deal from his blog otherwise.ReplyDelete
I remember an anecdote about Duncan M. at the height of his success and powers, wherein a writer (in MacLeans Magazine, before it became a right-wing rag, or maybe Weekend Magazine toward the end of its existence; I forget)interviewed DM at length and inserted an incident when the two of them were walking along a sidewalk in early winter.ReplyDelete
Dm spotted a police cruiser parked not faraway, gathered up some snow and heaved a snowball at it. Not only did it hit the cruiser, but the occupant got out and approached them. Turns out the cop had gone to school with DM, so no charges were laid. The writer was making the point of DM's iconoclastic and anti-authority nature, expressed spontaneously in a hurled snowball.
Oh why can't todays cartoonist draw such good political cartoons. The 50s really were a great era of political cartoons. Beautiful work,ReplyDelete
take care, Julie
.....Fantastic Lief.....ReplyDelete
"Oh why can't todays cartoonist draw such good political cartoons. "ReplyDelete
....mmmmm gee, that's because they teach you to get a "style" instead of honing a "craft".
Thanks for the post! I've used it on my blog...ReplyDelete
- Molly9:49 AM
I'm very proud to say that Bert Grassick was my grandfather. It's amazing to see that there are still people recognizing his amazing talent.ReplyDelete
Thankyou for highlighting his career, I'm sure he would be incredibly honoured.
Just found this today because I was commenting on some of Brian Gable's work for the Globe & Mail. Got me thinking of McPherson's work so I went searching.ReplyDelete
Thanks for sharing all of these! I was a kid when McPherson was at his peak but I remember them well, partly because I have a few of his originals. He knew and hung out with my mum and dad during WWII in London. He did a sketch of both of them plus a few others. I feel quite proud to have them still!
David Milne lived in Uxbridge then and I occasionally played with his son David. David's mother tried to repay some kindness showed by another schoolmate's mother by offering her one of David's oil paintings. The mother handed it back sniffing "I wouldn't hang that in the house.'ReplyDelete
Dr. Carl and Sheila Puterbough were dear friends of our family too. Carl made the mistake of turning down an offer of a painting for some dental work from David Milne too.
Later Duncan Macpherson moved to town. My dad told me a story about sitting with Duncan and David Milne on the train to Toronto. Somewhere near Stouffville David pointed out the window and remarked what a beautiful green this haystack was.
Duncan said he was crazy that haystack was red.
Dad said he didn't say anything but that haystack sure looked yellow to him
Duncan was a wild man. He was banned for life from the Uxbridge Legion at least 3 times.
One time he took my mother to the Stouffville Sales Barn auction to buy some garden tools. Duncan bid and got a huge box of garden tools for a dollar. There was an axe, a shovel, a rake, and a hoe even. but that came with a dozen or so old cellar window screens. As they carried them to the car Mother asked Duncan what she was going to do with all the screens. Don't you know anything? says Duncan as opened the nearest car door and threw them in the back seat and walked away.
I have four original MacPherson signed pictures never published or printed . Would anyone know what they would be worth ? Two are of Pierre Trudeau one is of Margret Thatcher and the other is of John Diefenbaker.ReplyDelete
I can say that I received a lot of interesting data because your article was very informative for me.ReplyDelete
I really like caricatures. I believe that the people who paint them have a rich inner worldReplyDelete
very nice blogs!!! i have to learning for lot of information for this sites...Sharing for wonderful information. Thanks for sharing this valuable information to our vision. You have posted a trust worthy blog keep sharing download instagram storiesReplyDelete
Shahzainistic is a children's YouTube channel featuring Shahzain.T, who is 5 years old along with his parents he makes interesting fun videos. The channel usually releases a new video regularly. ShahzainisticReplyDelete


text:
The new Department of Heritage minister is James Moore from the BC riding of Port Moody-Westwood-Port Coquitlam.
He first entered Parliament in 2004 and was named Secretary of State for Officials Languages, Pacific Gateway and the Vancouver-Whistler Olympics before he was announced yesterday as the Minister of Canadian Heritage and Official Languages.
The Heritage website is going to be closed tomorrow - presumbly to put Moore in as the minister, and to change some of the script on the website to reflect the new minister.
Josee Verner has been moved from the Heritage Department to Intergovemmental Affairs and is responsible for La Francophonie.
Greg Thompson is still the Minister of Veterans Affairs.


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text:
Getting Started
Styles and Purposes
Price Considerations
A comprehensive guide on what you need to know before choosing the right "interior door".
To separate living areas and spaces, interior doors close off the view and sound from one area into the next. Interior doors often go unnoticed, but the design can enhance the living space. Sound transmission (STC) is an important factor in choosing an interior door. While not considered for closet doors, STC ratings on interior doors sectioning off one room from another should be considered. Theater rooms are designed as sound-proof, with an STC of 60 but most rooms in a home do not require that level of noise blocking and STC 40 will soften or deaden the sounds from most conversations. An STC of 25 permits hearing normal conversations.
Solid Wood: Generally solid wood interior doors are six panel pine, but interior wood doors can be constructed from softwoods and/or hardwoods, such as mahogany, cherry, alder, maple, oak and pine. Solid wood doors must be maintained — stained or painted — on all surfaces as they will shrink and expand with changing humidity levels and temperatures in a building. With an STC of 35 to 40, solid wood doors will block most conversation sound transmission unless designed with glass inserts.
Medium Density Fiberboard: MDF is an engineered product of recycled wood fiber mixed with a resin and formed or molded into products, such as interior doors. The material is extremely stable and will not warp or shrink with changing temperatures or humidity levels. MDF does not have a grain and is easy to paint. Because doors are solid, MDF provides a similar weight to solid wood and STC levels of 32-35 (check with individual manufacturers).
Hollow Core: Constructed with a plywood or molded composite skin, these doors are hollow so sound and temperatures easily pass through. STC ratings vary but register as low as 20.
Solid Core: Constructed with a plywood or molded composite skin, these doors are filled between the skins with a wood fiber blend. STC ratings about 25-26 depending upon the filler blend.
Metal and Glass: In modern and contemporary homes, metal and glass doors are being used to accent the building's style. Glass doors or inserts do not provide privacy, but when closing off heavy traffic areas or closets, they add character to the space. Steel doors, frequently used in commercial or industrial buildings, have high STC ratings of over 50.
Panel Doors are the most commonly used interior doors. Created of solid wood or MDF the basic design has stiles, rails and six panels. Many manufacturers now create panel doors in a variety of designs, from two panels to five and six panels, with clear glass or translucent glass inserts. Solid panel doors are hinged and swing in or out, most frequently closing off bedrooms from the traffic areas of a home or in an office situation. Panel doors with glass panels may be used on closets or in traffic areas where privacy is not an issue.
Flush Doors are made of MDF or plywood as hollow core or solid core with a smooth skin; no stile, rail or panel design and are used in modern architecture.
Sliding Doors, constructed of wood, glass in metal, or mirror over wood or metal, travel along a railing. They do not impede traffic areas as they ride flush against a wall or closet.
Pocket Doors, most frequently found in older homes, slip between the walls of a room and the next room, saving space. When opened, they are not seen.
Folding Doors are usually found in small spaces as the door panels fold against each other. Used for closets, pantries, storage or laundry areas. Folding doors can be less wide panel doors or louver doors, which offer ventilation since the slats of the louver design are angled with air spaces between. Louver doors also can be hinged.
French Doors are named for two hinged panel doors, usually with glass panels, that meet in the center so they swing in or out together. Used in areas where light is to be brought into the room or for a view, French Doors are often seen connecting two rooms or a living area to a balcony, patio or deck.
Barn Doors now are used inside. Providing a design aesthetic, Barn Doors also save space as they hang from a rail and slide against the wall when open, covering the opening when closed. Space saving, they also become a feature of the space.
Hinges, knobs and/or levers come in myriad designs and materials. When choosing an interior door, match the style of doorknob to the door design. Levers should be used for contemporary or modern design, when aging-in-place is an issue, or for French Doors, where a push/pull function is needed.
Material: Solid Wood doors cost more, especially if exotic woods are chosen. Metal and Glass doors also can be more expensive than MDF, hollow core or solid core due to the later three being constructed of less expensive materials.
Style: A flat panel MDF or hollow core door are affordable and appropriate for use in most homes. Panel doors of wood will increase the price while French Doors will be more expensive since two doors are required to create the design.
Glazing: Adding decorative glass panels to an interior door will raise the cost.
Hardware: Simple nickel or brass door knobs and hinges are the least expensive. Nickel or brass lever style door handles also are not costly. If a special metal such as bronze is desired to meet a specific décor, the prices will increase.


text: Hello, I was wondering if it is possible to add a layer (sort of like an iframe) over a certain page.. for example site.com is a wordpress blog, but when people visit it, they only see the the iframe that is in the java code. Like a java layer over a website.. If you need more explanation please let me know. Thank you.


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This weekend the Symphony's soloist is violinist Mikhail Simonyan. In all my years of reading guest artists bios, Simonyan is the only artist that I've ever seen list SKYDIVING as a hobby! He is also helping young musicians in Afghanistan. He raises funds to help pay for music lessons there through a program called "Beethoven Not Bullets."
Still in his early twenties, violinists Mikhail Simonyan is already recognized as one of the most celebrated talents of his generation. The New York Times has praised his, "breadth, lyricism and fleet technique," and reported that "Mr. Simonyan play[s] as if every note counted." The Miami Herald has declared, "Mikhail Simonyan . . . played with the poise, perfection and inner burning fire of a master like David Oistrakh in his prime on a good night."
Mr. Simonyan, who hails from Novosibirsk, began to study the violin at the age of five. In 1999, at 13, Mr. Simonyan made his acclaimed New York debut at Lincoln Center with the American Russian Young Artists Orchestra (ARYO) and his debut in St. Petersburg, Russia at the Mariinsky (Kirov) Theatre.
This weekend's program is:
Friday, May 25 and Saturday, May 26 at 8 p.m. at the Majestic Theatre
Cristian Macelaru, conductor
Mikhail Simonyan, violin
Glinka Overture to Ruslan and Ludmila
Khachaturian Concerto for Violin
Copland Symphony No. 3
Jack Fishman
Email: firstname.lastname@example.com
For more blogs by Jack Fishman visit: www.sasymphony.org/blog


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By I. B. Neer
When scholars of the universe recreate spacemen along logical scientific lines, even those supposed weird little saucerites seem ordinary by comparison Prying eyes of science are probing into space again in the hope of detecting life on other planets. Armed with new facts, previously accepted theories about what lies beyond the Earth are being discarded by scientists every day and the possibility grows more and more distinct that creatures, more fantastic than our most vivid imaginations could conjure up, may inhabit the planets around us. They make those startling stories of weird little men in flying saucers seem tame by com-parison. Dr. Henry Norris Russell of Princeton recently threw a bombshell into scientific circles when he said: "It appears now to be probable that the number of inhabited worlds within the galaxy is considerable. To think of thousands, or even more, now appears far more reasonable than to sup-pose that our planet alone is the abode of life and reason." And H. Spencer Jones, Britain's Astron-omer Royal and one of the world's most noted inter-planetary authorities, de-clares: It is reasonable to suppose that life on any other world will have developed along forms that are entirely different from any with which we are familiar and that are possibly beyond our conception." Just how would those inhabitants look? Could they be men, beasts, plants or a combination of all three? To get the answer, experts in the field were polled. This question Was put to them: "Knowing what we do about conditions on other planets—differences in the constitution of the atmosphere, in the proportion of land and water, the temperatures and other phenomena what kind of people could conceivably inhabit them?"
Some startling answers resulted. However, all the experts pointed out one vital fact: on most planets, life as we know it cannot exist. An earthman would die at once on Mercury, his organs ruptured by the boiling of his blood in the tremendous heat of the sun if he weren't asphyxiated for lack of oxygen and dried up by lack of water. But the experts all agreed it is entirely possible that other planets may have developed their own life forms, en-tirely different from ours, suited to the very, very special conditions existing on their worlds! Let's go planet-hopping and take a look at a portrait gallery painted by the imagi-nations of inter-planetary experts. First to Venus because it is most like the earth in weight and size and, except for the moon, comes closer to us than any other globe. Scientists are convinced that the planet Venus has an atmosphere, but it is composed almost entirely of carbon diox-ide, with no detectable free oxygen. No evidence of water vapor has been observed, hence the surface of the planet must be largely desert, with no rivers, lakes or oceans.. What kind of people can live there?
John W. Campbell, Jr., a profound student of extra-terrestial life who is editor of Astounding Science-Fiction, a magazine which has successfully prophesied many of the most astounding recent scientific discoveries, says: "Life can exist on Venus without oxygen. Here on earth we have micro-organisms which can stay alive in sulphuric acid and kerosene. Undoubtedly there are life forms which can take the oxygen from carbon dioxide, and why can't these be creatures of flesh?" Would a Venus man look vaguely like a human? "Why not?" counters Mr. Camp-bell. "After all, the human form on Earth represents two billion years of experi-mental engineering on the part of nature. It is the best possible form to do the things it has to. There is every reason to suppose that life on Venus, or on any other planet, if it has developed to a high level, has taken human form. But this form would have to conform to the specific conditions of the planet."
Thus, Mr. Campbell points out, the lungs of a Venus inhabitant would have to be designed to perform a special function of extracting oxygen from carbon dioxide and his body cells would have a different chem-ical nature than ours. Now, since carbon dioxide is an extremely poor source of oxygen, a Venus man would have to breathe in considerable amounts to extract oxygen, hence his lungs would be de-veloped to enormous size, giving him a tre-mendous barrel chest. His food, Mr. Campbell says, would con-sist of fats and hydrocarbons. Trying to get life energy from these sources is like trying to burn gasoline under water it can be done, but you need an awful lot of gas. Therefore, a Venus man would have a grossly protuberant belly and heavy, col-umnar legs to support his bulk. Because his energy source is poor, his movements would be lumbering and sluggish. And since he must eat such huge quantities, he would literally eat himself out of house and home, living a nomadic life, constantly on the prowl for food. For this reason, Mr. Campbell thinks that the existence of a high culture on Venus is extremely doubtful since culture develops when people don't have to spend all their time just keeping alive. The Venus man would have no time to think, hence the race would be virtually beast-like. Now let's leap to Mars and observe a Martian as described by Major James R. Randolph, engineer, mathematician and physicist, who taught at Pratt Institute in Brooklyn, N. Y., and Rhode Island State College and lectures extensively on inter-planetary subjects.
This is his conception of a Mars inhabitant: He has slender arms and legs, a large chest, wide, flaring nostrils and a broad mouth. His head would be about a quarter the size of his body; his eyes would be dark-adapted, with wide pupils. His size is problematical—Major Randolph's guess is that he would be about four feet tall but he frankly admits there is no real basis for the assumption. Now, why would a Martian look like this? Gravity on Mars is only 38 per cent of what it is on earth, hence everything would be easier to push, pull, pick up and carry. If everything weighs less, there would be less need for muscle, hence the reed-like limbs. Why the large chest; the wide mouth and nostrils?
There is considerable evidence that Mars has an atmosphere but it is extremely thin and the pressure is very low. Now, says Major Randolph, since air occupies more space if there is less pressure, a Martian would have to take much more air into his lungs than we do and oversize organs would result. The mouth and nostrils would be wide for the same reason — larger air spaces would be required. The head, encompassing a normal brain, would be the size of an earthman's thus disproportionate to the rest of his body. Now come to Jupiter and prepare for a shock. Inhabitants who can conceivably live there are really something to see. The conditions on this planet are such that Jupiter man would have to be short, squat, with tremendous muscular developments and no eyes in his head! Yet despite this, he would be able to see in his own way. Mr. Campbell explains: "The massive muscles would evolve because gravity on Jupiter is two and a half to three times that of earth, requiring the expenditure of considerable energy. The atmosphere is so dense and deep that it is perpetual, unrelieved night, making eyes useless, hence undeveloped. "But why couldn't a Jupiter man see by a built-in sonar system, much like bats?"
Next, we Call on Saturn, Uranus and Nep-tune—the cold, remote wastes of the solar system. The atmospheres of these giant planets are known to contain hydrogen, marsh gas, helium, ammonia (on Saturn) and no oxygen at all. Such an atmosphere is poison-ous to Earth men. However, Fletcher Pratt, famous military and naval analyst and inter-planetary researchist, says: "Knowing what we know about these three giant planets, any life form there must be completely different from ours. It would have to use a nitrogen instead of an oxygen base, with lungs and other internal apparatus designed in such a way as to extract nitrogen from the atmospheric gases." Because of the known difficulty of ex-tracting nitrogen from methane and ammonia, the creatures would have to possess enormous intake surfaces, and since gravity on the three planets is extremely high, they would possess heavy, squat forms. Light would be absent because of the distance of the planets from the sun, hence, like Jupiter men, the inhabitants would not have eyes but "some sort of organ to keep from running into things."
Mercury, the fastest-moving planet in the solar system, has three lands—one of eternal day, one of eternal night and the third (the so-called intermediate zone) a land of light and darkness. The land of night is intensely cold, the land of day burning hot. But the sun alternately rises and sets in the area ,in between, producing temperature variations. Kenneth Heuer, lecturer at the Hayden Planetarium in New York City and author of the book Men of Other Planets, tells how a Mercurian might look. He would follow the shifting sun every moment to stay in the most favorable zone, Mr. Heuer says. This means that he would be on the move practically every Minute, would have no definite home, hence no culture could arise. A Mercurian would probably be four-footed, to make locomotion simpler. His food would consist of lower forms of vegeta-tion, such as lichens on rocks. And again, be-cause of the extremely tenuous atmosphere, the inhabitant would have a deep chest and large breathing orifices. Now, between Mars and Jupiter are more than 50,000 tiny worlds—minor planets called asteroids which have not been able to hold any atmosphere. They are airless, waterless, barren wastes. Hence, Mr. Heuer believes no life such as we are familiar with could pos-sibly exist. No life, that is, except . . . "Why couldn't mineral life exist there?" he asks. Rock men? "Exactly. Mineral life could best withstand the conditions which, as far as we know, are totally devoid of any animal life-sustaining factors." How would they move or talk? 'Whey wouldn't move. They would remain eternally where they are. And why couldn't they communicate with one another by some form of telepathy?" There you have them—the creatures of other worlds as come to life in the scientific imaginations of the experts. Perhaps in cen-turies to come, man will span the vast reaches of the universe and at long last come face to face with his neighbors in space. Until that time, however, we can only sit at our instruments, study the heavens and, based on what we see, let our imagination roam into other worlds.


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The UK's National Consumer Council today asked the Office of Fair Trading to investigate 17 software companies on the grounds that their product license agreements were both confusing and unfair to consumers. The group also issued a larger report designed to shed light on the problems caused by End User License Agreements (EULAs), and it concluded that steps should be taken on both the UK and European level to make the agreements more readable, easier to access, and more fair.
The group purchased 25 separate software programs last year, all of which required the buyer to accept an onscreen EULA before the software would complete its installation. 14 of the 25 programs did not mention anywhere on the packaging that the software required EULA acceptance to install. Of the programs that did provide such notification, only four gave a URL so that users could look up the EULA before purchasing the product. For the rest of the programs, users needed to open the software and begin installation before even seeing the agreement, at which point it can be difficult to return the software.
Another key problem is that software is sold all over the world, but EULAs are often tailored only to specific jurisdictions. Most of the tested software came from Germany, England, Ireland, the US, and Canada, but took little account of the actual laws that exist in other places. For instance, McAfee's Total Protection 2007 was the only product that even asked for information about the country in which the end user lived. While that's certainly a step in the right direction, the National Consumer Council notes that "the text for different countries with the same first language was identical, regardless of any differences in local consumer law."
Finally, some of the license terms seem downright draconian. Cakewalk's Music Creator 3, for example, requires users to click a checkbox that says, "I understand that I can not transfer or sell the software."
The NCC hopes that the Office of Fair Trading will take action by examining the "potentially unfair contract terms" identified by the report and launching a market study on the fairness of such EULAs in general.
This is not the first time that EULAs have been targeted by consumer groups and regulators, of course. Here in the US, the FTC has shown its willingness to crack down on egregiously deceptive EULAs, though it has shown no appetite for requesting significant changes from mainstream software companies. The UK's Ofcom (the country's communications regulator) has also intervened to tweak contracts when the wording was unfair, deceptive, or simply confusing.
Court cases have also tried to rein in EULAs, specifically targeting those agreements which state that software consumers have only purchased a "license" to the code in question and not an actual product.
Further reading:
- The NCC report (PDF)
- The NCC's announcement regarding its complaint to the Office of Fair Trading
- The Register brought the story to our attention


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Hello, Growtopians!
It's time to commence the new cycle! So, we're opening a new thread and a new option to submit your WOTD entries!
What do you get when you win WOTD?
- An awesome trophy magically appears in your inventory
- "WOTD Winner" is shown every time someone enters your world
- Your world is added to the WOTD winner's list in-game: /top
- 10 Growtokens
- And above all! RESPECT!
Cool right?
But there are regulations to follow to be eligible to win the much coveted WOTD Award!
- World name
- Your GrowID (because we can't see them sometimes and just in-case you changed your name. )
- A quick description of your world
- Latest Render of the world
**NEW!** We are now allowing players to submit their entries on INSTAGRAM. Just post your entry with the "Entry Requirements" and include this hashtag:
- For December entries: #growwotddec19
- For January entries: #growwotdjan20
- For February entries: #growwotdfeb20
RULES (December 2019 - February 2020 Cycle)
- Owners should be the ones nominating their worlds. Nobody else is allowed to submit your entry for you.
- A Bulletin board next to the white door giving credit to other players who helped with building/funding the world, music creator, worlds they have inspired/copied design from (If it's from the Web please mention that) and any other information should be mentioned. You can also use alternative boards, such as Guestbook.(You can choose to represent this info in a different creative way if you like but it must be near the start area of the world so we can easily see and check them)
- You must credit pixel art sources and/or music inspiration.
- At least basic Jammers (Punch and Zombie) must be placed within the world, unless the world does not require having one of them. Note: Promising that the jammers will be placed inside the world if it wins will not be considered.
- Vend worlds, Storage and Pixel Art only worlds will not be considered.
- Guild Headquarters (Worlds) are welcome! However, as the world is owned by one person, the prize will only be given to the owner. It's up to the Guild how they will make use of the WOTD prize in case the world wins.
So you want to win eh?
- Plus points are given to in-game event theme worlds which explain old and/or new mechanics of the in-game event to help guide new players
- Plus points are given to worlds with new/creative ideas or unique/original mechanics
- Plus points are given to worlds using recent items/blocks from recent or current events
- Plus points are given to worlds placing doors/portals to worlds they have inspired/copied design, music and anything else from.
- Negative points are given to worlds with doors linking to Vend/Shop worlds or any other worlds that are not related.
- Owners who have been banned for more than 3 days in the last 6 months WILL NOT be considered.
**If the punishment has been cancelled before it expires automatically, the ban is not counted and the player/world will still be eligible for the WOTD.
What are the changes made in this cycle?
- We added INSTAGRAM as an additional venue to submit WOTD entries, provided the post includes the "Entry Requirements" and the #GROWWOTD hashtag. To make it easier for players to submit entries and to give other players who has no access to the forum to submit theirs too.
- We will only look at the world owner's punishment/s. We will no longer consider the admins' ban record.
- We will not consider owners who were banned for more than 3 days in the last 6 months.
- We are now allowing a world entry to be submitted more than once but with a 3 day gap. (PLEASE DO NOT SPAM)
Would I be able to nominate my world in the next cycle and have a chance to be chosen as WOTD?
- Yes, you can nominate your world every cycle but we highly encourage you to try and make improvements in the world rather than just nominating the same world as it is in the next cycle. We also encourage you to create a thread to collect feedback on how to improve your world and we might leave some comments there in some rare cases.
My world was chosen as a WOTD before the 2018 trophy was launched, am I eligible to get the new trophy?
- Yes, you are! Simply make sure you have the Ultra Trophy 3000 in your inventory and contact support, we will replace the Ultra Trophy 3000 with the new 2018 version.
Can I nominate more than one world in the same cycle?
- Yes, you can! You can nominate as many worlds in the same cycle as you like.
Why do copied worlds get plus points? Does this mean I can just copy a world and win?
- Most probably will have nearly ZERO chance of winning a WOTD if you choose to simply copy an old WOTD. The whole point of this rule is simply we don't mind if you end up copying a small part from a previous world (a cool looking tower, house decoration ...etc) as long as you are honest enough to clearly show that in your world (which we also hope that would give credit to the original owner and traffic to his/her world) but that will also mean your world must be different enough!
Alrighty then! That should explain everything. Now go create your world and start submitting!


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Hello Everyone.
I'm HisPurpleness on Deviantart. I'm working on my own Sanguo Adaptation, Sanguo Legends.
I can rework the name if necessary.
Here are some illustrations I've worked on so far
Guan Yu VS Hua Xiong
Shan Fu (Xu Shu) and Pang Tong
Cai Mao
Jiang Wei and Wang Ping
Cao Cao and Xun Yu
Gan Ning
The Sun Family (See if you can guess who's who)
Sima Yi
Please let me know if you're interested in seeing more.
Your feedback is invaluable.


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Sir John Major, KG, CH, ACIB (born 29 March 1943) is a British Conservative politician, who served as Prime Minister of the United Kingdom and Leader of the Conservative Party from 1990–1997. He held the posts of Foreign Secretary and Chancellor of the Exchequer in the cabinet of Margaret Thatcher and was the Member of Parliament (MP) for Huntingdon 1979–2001.
Despite Thatcher's "notorious" assertion that "she expected to continue in control as a backseat driver," Major's mild and consensual style was seen as complete contrast to Thatcher's forceful and confrontational manner. Early in his term, he presided over British participation in the First Gulf War (March 1991) and negotiated "Game, Set and Match for Britain" at the Maastricht Treaty (December 1991). Despite the British economy then being in recession he led the Conservatives to a fourth consecutive election victory, winning the most votes in British electoral history in the 1992 general election, albeit with a much reduced majority in the House of Commons.
Major's premiership saw the world go through a period of political and military transition after the end of the Cold War. This included the growing importance of the European Union, an issue which was already a source of friction within the Conservative Party owing to its importance in the decline and fall of Margaret Thatcher. Major and his government were responsible for the United Kingdom's exit from the Exchange Rate Mechanism (ERM) after Black Wednesday on 16 September 1992, after which the Conservatives never gained a lead in the opinion polls.


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When I was 13 a friend of my mother's told me that black really suited me (I was dressed head to toe in it), much to my mother's chagrin. Being an impressionable age, I took the compliment to heart and have been pretty much obsessed with black ever since. Living in Melbourne, which is the Australian equivalent to New York - it looks like a sea of black and grey in winter, certainly helped.
Shoreditch House, London
A Tom Scheerer interior - it looks quite warm and inviting, don't you think?
Kelly Wearstler's incredibly chic black kitchen, from Domicilium Decoratus
Exterior of Yael Arfallo's house, from Domino magazine
One of my favorite fashion designers, Martin Grant - a Melbourne boy based in Paris. He even went to the same University that I did!
"Black Paintings" Authored by Mark Rothko, Robert Rauschenberg and Ad Reinhardt, this is a collection of black paintings that were creating in America in the 40's.
40's American armchair, covered in jet black patent leather, from 1st Dibs.


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What a line up! Our annual BFA Senior Thesis Exhibition opens this week, followed by First Friday and the Annual Beaux Arts Ball! Join us for these wonderful art related events:
This year's exhibition is split between two galleries, so be sure to visit both and see the amazing work of our graduating seniors. The opening reception for the Gallery of Visual Arts exhibition will take place from 5-7pm on Thursday, May 1st, and the UC Gallery reception will run from 4-6pm the same evening. Both exhibitions will end on May 16th.
Our friends over at Missoula Community Access Television are pleased to host the reception for Valley Christian High School students whose works are on display. Enjoy refreshments and student art from 5-8pm.
Once again, our friends over at The Brink are hosting the "On Deck" exhibition and auction of skateboards customized by artists from Missoula and all over the country. Let's drop some names: This year's show and auction will feature approximately 54 custom skateboard decks created by artists from Montana, such as Larkin Matoon, Trevor Parr, Courtney Blazon, Athena Lonsdale and Jack Metcalf. The auction will also include a unique piece from Japan-based artist Haroshi. The reception and auction will run from 5-10pm.
Clay Studio of Missoula:
Stop by the clay studio to see the latest from Artist in Residence Lilly Zuckerman! This solo exhibition features the work artist in residence Lilly Zuckerman has been developing during her two year residency at the Clay Studio of Missoula.
School of Art 3D Technician Gary Batzloff will be presenting his works in the tiny alternative space run by our grad students. Stop by the alley behind the Old Post Pub to see Gary's works from 6-9pm.
Don't forget to pay a visit to the MAM this First Friday! Local artist Alison Reintjes will speak about her site specific sculptural installations at 7pm. There will be tasty beverages, too!
Beaux Arts Ball:
The Associated Students of the University of Montana's student art club, The Artists' Collective, invites you to experience an evening of magic, wizardry and dragons. How could you possibly turn down such and invitation? There will be dragons! Join the UMAC kids at Stage 112 (the Elks Lodge) for their annual party and fundraiser. Tickets are available prior to the event for $5 and at the door for $7. Costumes are encouraged and prizes will be available from several categories!
This Blog:
If you have an item or event you would like to share with our community, EMAIL us and we'll consider it for publication. Have a safe and happy First Friday, and do be careful of those dragons.


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|Southeast Spotlight
Operation Christmas Child provides hope to children
Published: 11/17/2011 13:40:00
There's a very special project taking place in advance of the holiday season. It's a chance to help a child that may not have a merry Christmas without your help, it's called operation Christmas Child and we spoke with Tom Brice, the Southeast Alaska Area Coordinator, to find out what it's all about.
VIDEO: There's a very special project taking place in advance of the holiday season. It's a chance to help a child that may not have a Merry Christmas without your help. (Image: Operation Christmas Child)
"Operation Christmas Child is a project put on by Samaritan's Purse, which is an international relief organization, meant to go into third world nations, war torn nations, providing food and community assistance. This project, OCC is very focused on children and it's the largest children's focus project through Samaritan's Purse. The idea is to give a kid a little bit of hope in a world where they might not see any. The hope comes through in the form of a shoebox; packed full of candy, toys, toothbrushes, toothpaste; those types of items where the child actually has the ability to recognize that somebody cares for them. Not only that but it's important to put a picture of you and your family, maybe a small letter, something that the child can see that there is a face associated with the gift that they've been given. Another thing people like to pack are plastic Rubbermaid or Tupperware boxes that are roughly the same dimension of a shoebox."
That also provides a container that the child can use, but you don't even have to have a box to contribute.
Tom added, "If you don't have your own shoeboxes, we have extra go boxes available at the drop off location here at Chapel by the Lake."
Operation Christmas Child will be accepting boxes until 4pm next Monday the 21st at Chapel by the Lake.
By: Rik Pruett - firstname.lastname@example.com


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- Inside Athletics
- Tickets
- Fan Zone
- Media Zone
- Social
- Shop
- Donate Now
JOHNSON CITY, Tenn. (Dec. 16, 2013) – Junior guards Jalen Riley (Racine, Wisc.) and Rashawn Rembert (Tampa) posted career highs and combined to score 54 points, as the ETSU men's basketball team outpaced Tusculum 108-87 in a non-conference game highlighted by plenty of offense Monday evening inside the ETSU/MSHA Athletic Center.
Riley finished with a game-high 28 points and Rembert added 26, as the Buccaneers shot 54 percent from the field as a team and improved to 5-6 on the year. Meanwhile, Tusculum dropped to 1-11 on the season.
"We've now won five of our last seven and we're getting better," said ETSU head coach Murry Bartow. "I saw a lot of good things tonight offensively, especially with a few guys that we normally count on to score not really getting it going. We also didn't have Hunter (Harris) due to a family situation, but other guys stepped in and played well."
ETSU also shot 41 percent from 3-point range and 87 percent from the foul line, out-rebounding the Pioneers 41-30 and outscoring Tusculum 42-28 in the paint. The Bucs also enjoyed a 51-31 advantage in points off the bench.
Along with Riley and Rembert's efforts, the Bucs got 13 points and nine rebounds from sophomore forward Lester Wilson (Knoxville), while true freshman post Isaac Banks (New Orleans) came off the bench to pitch in 12 points and nine rebounds.
Tusculum actually trailed by just two in the early going before Banks scored six straight points to make it 24-16 with 10 minutes left in the first half. From there, ETSU would outscore the Pioneers 25-19 to close out the half with a 49-35 advantage.
In the second half, the Bucs methodically built their lead to as many as 29 points at 98-69 with 6:37 left in the game. At that point, the Pioneers managed to cut into the advantage and finish 21 points off the pace.
For Tusculum, Addison Flynn scored a team-high 20 points, while Chase Mounce netted 18, Darius Carter added 13, and Jalen Walker collected 10.
The Bucs will return to action on Saturday afternoon, taking on Austin Peay inside the Dome. Tip for that contest is set for 4 p.m.
For more on ETSU men's basketball throughout the 2013-14 season, visit ETSUBucs.com and click on the men's hoops link.


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My thoughts on Labour's policy review.
Stay Keynseian on economic policy
Keep going Ed-Balls-style. Never abandon John Maynard Keynes. We stand for jobs and growth. If we need to tax, we tax the rich – and if they leave the country, good riddance to parasitic traitorous scum. People first.
Go federal on Europe
Tell it as it is: we need an EU fiscal policy to sort out the Greek mess. Britain should be an enthusiastic supporter of an EU finance ministry and of an EU-wide Keynesian public works programme concentrated on transport and telecommunications infrastructure. Whether we join the euro is another matter, but it shouldn't be ruled out. In the long run, we should be part of a federal Europe. Meanwhile, we need more power for the European Parliament. Its current incumbents are hopeless, but it's the only way to keep the EU bureaucracy under control. People's Europe.
Embrace citizen's income
Abolish pensions and every other benefit – along with income tax allowances – and introduce a flat citizen's income.Means-testing dies. Everyone gets a basic income every week, then pays tax on everything they earn on top of it – end of story. There would have to be some means-tested supplements for the disabled, and dealing with children and immigrants is an issue … but these are minor details. Everyone deserves a living.
Democratise the state
An elected second chamber is the bare minimum. Add PR for the Commons, elected regional assmblies and a federal consttituion for the UK on the German model and we're moving. Restore local authorities' right to set taxation as they choose. Power to the people.
Axe military spending
Abandon nuclear arms and hi-tech fighter aircraft. They are a monumental waste of money. Spend the cash saved on education and encouraging small businesses. Make peace, not war.
Take it easy on health
Play it by ear. What we've got is pretty good and we need to defend it. NHS: keep it free.
Set education free
Abandon the national curriculum and give curriculum control back to local education authorities. Insist they all teach history. Elect local education authorities directly. Set up a libertarian free school in every city. Sack the "quality assurance" bureaucracies in further and higher education and employ more lecturers. Replace student loans with a retrospective graduate tax levied on everyone who has a degree – even those who were at university in the 1950s. Let's learn.
Kick ass on housing
Build council homes and reintroduce rent controls. Set up a private landlord register and nationalise the biggest landlords, then hand over control to democratic housing co-ops. Give mortgage-holders the right to convert their loan into a council tenancy. A home for every household.
Go in hard on transport
Renationalise the railways and introduce serious tax measures to curb the private motor car. Then legislate to make all local bus companies user-controlled co-ops. Move on.
Play it soft on law and order
Keep it under control: there's no solution. String 'em up, it's the only language they understand.
OK, that's it. But of course I've been here before.


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The Tsar's Bride 28 January 2020 - 19:00
Opera The Tsar's Bride will be showing at the Bolshoi Theater on 28.01.2020 19:00.
Bolshoi Theater Stage: Historic Stage
Performed with two intervals. Running time: 3 hours 30 minutes.
When ordering tickets for The Tsar's Bride, you will receive:
- Free delivery in Moscow and Saint Petersburg
- Your own manager to help you with any questions
Payment methods:
- Cash
- Credit/Debit Card
- Western Union
- Wire-transfer
- etc.
You can also call us and order tickets: +7 (495) 150-25-05


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Do you ever get tired of having to chain your wallets to your belt to keep from getting hosed?
My wife and I are off tomorrow for a long deserved vacation at my favorite beach spot, which shall remain nameless, but you will all probably recognize. We live near San Francisco; I have all my life, and have no illusion that there are banditos in every major city and vacation area we have ever been in. I would say that it's global, but there are places that they cut people's hands off for that kind of thing, I just have never been there.
Having been a road warrior and international vacationer for 30+ years, and my wife been in corporate travel management almost as long, it seems like we've been screwed by just about every nationality from Cabo to Rome to Boston and back home.
This trip will be no different, were just getting smarter. Last time we were down, we reserved a car from National, Paid the liability insurance, and arrived at the desk to pick up our car to be informed (again, it happens every year) that we were required to take their collision insurance as well. This raised the price of our "economy" car from $16 a day to $45 a day. $29 a day for insurance? How is it that I can insure two $35,000 + cars in a major metropolitan area for less than $7 a day for two people, but in my favorite not so little resort area it costs $29 to insure a freeking five year old Volkswagen Jetta? Gotcha!
I tried my usual offer to the manager to leave a deposit on my credit card, which has worked for the last 30 years. No dice. They apparently have now unionized. I looked at all the discount offers on the internet and they are all the same. They offer really cheap car rates, then tack on the extra fees much the way airlines have started charging for bags. To add insult to injury, to avoid the bandits at the airport we decided to take a transfer to our time-share, and then get a car a few days later from the concierge. They now have a National Rent-a-Car in the lobby (it is a Sheraton property) and the car that the thieves at the airport wanted $45 a day for, is now being pimped for $65 a day. Being that we have two golf courses, 6 pools, 3 restaurants, two small stores with relatively reasonable prices, and we are bringing enough of our own food for several meals, I think we can whale watch for 3 or 4 days and then rent a car to go through the tourist corridor to have our Cheeseburger in Paradise next to Sammy Hagar's joint. We can get enough snorkeling in before we leave, and return home with the usual stories of the Marlin that got away.
Since we will be returning the car full to avoid their $10 a gallon surcharge, we will have the wonderful experience of the gas station once again. Not only are you not allowed to pump your own gas, got forbid there is ANY action that does not involve at least three layers of tipping; there is always the payment game. It is absolutely imperative to watch the gas pump. Somehow if you don't, your Jetta miraculously needed 30 gallons of gas in a 20 gallon tank. No I am not confusing liters for gallons, I can do the math.
When you pay in the local currency the exchange rate is usually pretty simple, like 10:1. If it is supposed to be 11.5:1, you still get 10. Not a huge problem. In several countries the denominations of bills are suspiciously colored for similar denominations. In this case a 500 is the same color as a 50. Be very very careful when you hand a 500 to someone, you make him acknowledge that you have indeed handed him the 500. I've had this one pulled on me on three continents. They take the red 500, go back to the cash register (always out of eye shot) and come back and hold out a 50 and tell you that indeed, that was what you had given them. Easy 450 for them, and there isn't a damn thing you can do about it.
I've had two camera bags actually cut off of my person, or someone I was with. They come up behind you on a Vespa motorcycle, silent and small, slice the strap, grab, and are gone. They don't even have to slow down much to do it. I've been pick-pocketed by a five year old while stopped to give a supposedly dying old lady a dollar. We've endured the slums of Mumbai and Bangalore and grossly physically deformed beggars in Bahia del Salvador. I've had a knife pulled on me near Haight-Ashbury in my own home town. Has that ever stopped me from travelling? No, I just have become a bit more cautious in my old age.
Enough of my whining. It's time to pack my tequila, salt, and ice chest so I can be sipping from my $18 quart bottle of Hornitos while I watch the bloated turistos from Milwaukee drinking their $10 watered down margaritas by the pool. I fear we have watched far too much Tony Bourdain to not have become somewhat jaded.


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I using a Vector Layer with the HTTP protocol to request GeoJSON from my web server, and am trying to get this GeoJSON to display on my map. The GET request appears to be working correctly, as I can see the example JSON I requested in Firebug. However, I am getting an error telling me that "this.format is null Openlayers.js (line 1186)". Unfortunately, the OpenLayers.js file is essentially unreadable so I am having a hard time figuring out what my problem might be.
I set the format for the Vector Layer to GeoJSON. My code for the layer is below:
var newLayer = new OpenLayers.Layer.Vector("Filtered by Zoom Level", {
strategies: [new OpenLayers.Strategy.BBOX(),
protocol: new OpenLayers.Protocol.HTTP({
url: "http://server:8080/test-webapp/servlet",
filter: filter,
styleMap: styleMap,
format: new OpenLayers.Format.GeoJSON({
externalProjection: new OpenLayers.Projection("EPSG:4326"),
internalProject: new OpenLayers.Projection("EPSG:900913")
Does anybody have any ideas as to what the issue might be?


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Madhavi Kadakia, PhD
Ph.D.: University of Pittsburgh (1995)
Postdoctoral: Pittsburgh Cancer Institute (1995–1998)
The Cancer Institute of New Jersey (1998–1999)
My laboratory is focused on deciphering the signaling pathways regulated by p63 and its role in cancer and development. p63 is a member of the p53 family member and has been shown to play a role in tumorigenesis, maintenance of epithelial stem cells and development. p63 has a complex genomic organization that results from alternate promoter usage and alternative splicing and is a homolog of the tumor suppressor protein p53. Unlike the p53 knockout mice which exhibit a high incidence of spontaneous tumors, the p63 knockout mice displays severe developmental abnormalities including limb truncations and craniofacial abnormalities. p63 mutations are also observed in various human developmental syndromes.
Our laboratory has been involved in understanding the signaling pathways regulated by p63 to better understand the role of p63 in development as well as cancer. We have studied the effects of naturally occurring mutant forms of p63 on the biological activity of p53 and p63 and shown that the mutant p63 differentially regulates known p53 and p63 target genes and could explain the difference in the biology of two members of the p53 family, p53 and p63. We have shown that p63 regulates sonic hedgehog, known to be important in both development and cancer. Recently we demonstrated that ΔNp63α, the most abundant and physiologically relevant p63 isoform, negatively regulates PTEN, a tumor suppressor gene often deregulated in a variety of cancer including the model system we focus on in my laboratory, skin cancer. Our studies on examining the role of p63 in cancer progression demonstrated that vitamin D receptor (VDR) is regulated by p63 and p73, another member of the p53 family and its biological significance. Currently studies in my laboratory are focused on examining the mechanism behind feedback regulation of p63 by VDR and VD3.These studies will address the discrepancy whether VD3 inhibits or promotes cell survival and provide further insight into its use as a chemotherapeutic adjuvant for anti-cancer therapy and fill the gap in the understanding of VD3 mediated regulation of ΔNp63α levels and its role in the development and progression of non melanoma skin cancer.
Recently my laboratory has been involved in examining the differential expression of known microRNAs and unknown small RNAs in tissue and plasma sample of patients with Barrett's esophagus (BE), Esophageal adenocarcinoma (EAC) in order to identify circulating microRNA biomarkers for early detection of EAC using next generation sequencing. My laboratory has recently received funding to obtain next generation sequencer along with the top of the line Real time PCR machine with high throughput capabilities to facilitate these studies.
Kadakia Lab 2015
- Hill NT, Zhang J. Leonard MK, Lee M, Shamma HN, Kadakia MP*. 1a- 25 Dihydroxyvitamin D3 and the vitamin D receptor regulates DNp63a levels and cell proliferation. 2015. Cell Death Dis 6:e1781. doi: 10.1038/cddis.
- Hill NT, Gracia-Maldonado GH, Leonard MK, Harper AR, Tober KL, Oberyszyn TM, Kadakia MP*. Role of Vitamin D3 in Modulation of DNp63a Expression during UVB induced Tumor Formation in SKH-1 mice. 2014. PLoS One. 9(9):e107052.
- Lehman JA, Hauck, PM, Gendron JM, Batuello CN, Eitel JA, Albig A, Kadakia MP, Mayo LD. Serdemetan Antagonizes the Mdm2-HIF1a Axis Leading to Decreased Levels of Glycolytic Enzymes. 2013. PLOS One. 8(9): e74741.
- Leonard MK, Hill NT, Bubulya PA, Kadakia MP*. The PTEN-AKt pathway impacts the integrity and composition of mitotic centrosomes. 2013. Cell Cycle. 12(9): 1406-15.
- Leonard MK, Hill NT, Grant ED, Kadakia MP*. ΔNp63α represses nuclear translocation of PTEN by inhibition of Nedd4-1 in keratinocytes. 2013. Arch Dermatol Res. Apr 16 (Epub ahead of print).
- Singh AP, Arora S, Bhardwaj A, Srivastava SK, Kadakia MP, Wang B, Grizzle WE, Owen LB, Singh S. CXCL12/CXCR4 Protein Signaling Axis Induces Sonic Hedgehog Expression in Pancreatic Cancer Cells via Extracellular Regulated Kinase- and Akt Kinase-mediated Activation of Nuclear Factor κB: Implications for Bidirectional Tumor-Stromal Interactions. 2012. J. Biol. Chem. 287: 39115-24.
- Chen J, Yang J, Chen S, Jameson J, Swope VB, Cheng T, Kadakia MP , Abdel-Malek Z, Kadekaro AL.a-Melanocyte Stimulating Hormone Suppresses Oxidative Stress Through a p53-Mediated Signaling Pathway in Human Melanocytes. 2012. Mol. Can. Res. 10: 778-786.
- Kadakia MP*, de-Fromentol CC, and Sabapathy K. The 5th International p63/p73 workshop: much more than just tumor suppression. 2012. Cell Death Differ 19(3): 549-50.
- Leonard MK, Kommagani R, Payal V, Mayo LD, Shamma HN and Kadakia MP*. ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization. 2011. Cell Death Differ 18(12):1924-33.
- Vaiana CA, Leonard MK, Drummy LF, Singh KM, Bubulya A, Vaia RA, Naik RR, Kadakia MP*. Epidermal Growth Factor-Layered Silicate Nanocomposites for Tissue Regeneration. 2011. Biomacromolecules.12(9):3139-46
- Lehman JA, Waning DL, Batuello CN, Cipriano R, Kadakia MP, Mayo LD. Induction of apoptotic genes by a p73-PTEN complex in response to genotoxic stress. 2011. J Bio. Chem. 286(42):36631-40
- Mieszawska AJ, Llamas JG, Vaiana CA, Kadakia MP, Naik RR, Kaplan DL. Clay enriched silk biomaterials for bone formation. 2011. Acta Biomater. Apr 22. 7(8): 3036-41.
- Sharma A, Markey M, Torres-Munoz K, Shah-Varia S, Kadakia MP, Bubulya A, Bubulya PA. Son Maintains Accurate Splicing for a Subset of Human Pre-mRNAs. 2011. J. Cell Sci. 124 (24):4286-98.
- Basu S and Kadakia MP*. The 4th International p63/p73 workshop: p53's (older) sisters take center stage. 2010. Cell Death Differ.17(3): 562-564.
- Kommagani R, Whitlatch A. Leonard MK, Kadakia MP*. p73 is essential for vitamin D mediated osteoblastic differentiation. 2010. Cell Death Differ. 17(3): 398-407.
- Kommagani R, Leonard MK, Lewis S. Romano RA, Sinha S, Kadakia MP*. Regulation of VDR by ΔNp63α is associated with inhibition of cell invasion. 2009. J cell Sci. 122(16): 2828-35.
- Khokhar, SK., Kommagani, R., & Kadakia, MP.* Differential effects of p63 mutants on transactivation of p53 and/or p63 responsive genes. 2008. Cell Res. 18(10):1061-73.
- Kommagani, R., Payal, V., & Kadakia, MP.* Differential regulation of Vitamin D Receptor by the p53 family: p73 Dependent Induction of VDR upon DNA Damage.2007. J. Biol. Chem. 282 (41), 29847-29854.
- Paull, DE, Kelley, K, Moezzi, J, Kadakia, MP, & Berberich, SJ. Gene Expression Profiles from Needle Biopsies of Non-Small Cell Lung Carcinomas Provide Useful Signatures of the Primary Tumor. 2007.Biomarker Insights 2:253-259.
- Gupta MK, Khokhar SK, Phillips DM, Sowards LA, Drummy LF, Kadakia MP*, & Naik RR. Patterned Silk Films Cast from Ionic Liquid Solubilized Fibroin as Scaffolds for Cell Growth 2007. Langmuir 23:1315-9.
- Caserta TM, Kommagani R., Yuan Z., Robbins DJ, Mercer CA, & Kadakia MP*. p63Overexpression induces the expression of Sonic Hedgehog. 2006, Mol. Can. Res. 4:759-68.
- Heminger K., Jain V., Kadakia MP, Dwarakanath B., & Berberich SJ. Altered Gene Expression Induced by Ionizing Radiation and Glycol tic Inhibitor 2-Deoxy-Glucose in a Human Glioma Cell Line: Implications for Radio Sensitization.2006. Cancer Biol Ther.5:815-23.
- Kommagani R., Caserta TM, Kadakia MP.* Identification of vitamin D receptor as a target of p63. 2006. Oncogene25:3745-51.
- Rozenzhak SM, Kadakia MP, Caserta TM, Westbrook TR, Stone MO, & Naik RR. Cellular internalization and targeting of semiconductor quantum dots.2005. Chem Commun. 7:2217-9.
- Kadakia MP, Brown TL, McGorry M, & Berberich SJ. MdmX inhibits Smad transactivation. 2002. Oncogene21:8776-85.
- Kadakia MP, Slader C, & Berberich SJ. Regulation of p63 function of Mdm2 and MdmX. 2000. DNA Cell Biol.20(6):321-330
- Goydos J & Kadakia MP. The Clinical Relevance of the Fas-FasL Interaction. 1999. Cancer Therapeutics.2:107-112.
- Goydos J, Kadakia MP, Tirabassi MV, Perez D, & White E. Rendering Cells Resistant to Fas Ligand-Induced Apoptosis. 1999. Surgical Forum.50: 341-342
- Goydos J, Kadakia MP, Tirabassi MV, Doshi M, Perez D, & White E. Rendering Immune Effector Cells Resistant to Fas Ligand-Induced Apoptosis. 1999. J. Surg. Res. 86:275
- Kadakia MP*. Human Herpesvirus 6 Infection and Associated Pathogenesis Following Bone Marrow Transplantation. 1998. Leukemia and Lymphoma 31: 251-266.
- Kadakia MP*, Rybka WB, Stewart JA, Patton JL, Stamey FR, Elsawy M, Pellett PE, & Armstrong JA. Human Herpesvirus 6: Infection and Disease Following Autologous and Allogeneic Bone Marrow Transplantation. 1996. Blood 87: 5341-5354.
2010 Faculty Mentor Award
Boonshoft School of Medicine, Wright State University
2011 Visiting Research Scholar Fellowship
Nottingham Trent University, United Kingdom
2011 Visiting scientist
Medical Research Council, Leicester, United Kingdom
2011 Organizing committee member
5th International p63/p73 workshop, Lyon, France 2011
2013 Organizing committee member
6th International p63/p73 workshop, Chiba, Japan 2013
Active Research Grant Awards
NIH/NCI, RO1 award, P.I.
4/1/12 – 3/31/17 — "Role of ΔNp63α in vitamin D mediated cell survival in skin cancer"
Department University Research Instrumentation Program (DURIP), P.I.
7/1/2013 – 6/30/2014 — "Genomic Tools for Identification and Characterization of Biorecognition Elements for Human Performance Monitoring"