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News - April 2012 - Portland State University
|April 2012
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Monday, April 2, 2012
»Stanford Economist Gavin Wright, "The Civil Rights Revolution in the South: Who Won, Who Lost?" May 10 at PSU
»Eric Fruits on academic advisory board member for Taking Sides: Clashing Views in Urban Studies textbook
»Evguenia Davidova presents "Health Perceptions, Medical Practices, and Medicine Consumption among Nineteenth-Century Balkan Merchants" at the ACLU Workshop
»Ruth Falco presents "From Universal Design to Universal Design for Learning" to Portland Public Schools committee
»Becki Hunt Ingersoll, Doug Siegler, and James Ofsink present Last Mile project to regional advising association conference
»Jason Jurjevich presents "Where Young People Go to Retire? Amenities, Employment Opportunity and Migration Patterns of the Young and College-Educated" at Association of American Geographers conference
»Mary King presents "The Hidden Experience of Mexican Migrant Women" at University of Oregon Wayne Morse Center for Law and Politics Symposium
»Susan Kirtley present "Through a Glass Darkly: Linda Barry's Images of Girlhood" at Gender Studies Symposium
»Sean Kohles co-authors "Biokinetic Mechanisms Linked With Musculoskeletal Health Disparities: Stochastic Models Applying Tikhonov's Theorem to Biomolecule Homeostasis" published in the Journal of Nanotechnology in Engineering and Medicine
»Masami Nishishiba, Kevin Kecskes present workshop Building Multidisciplinary, Community-Connected Academic Programs for Civic Leadership, at 2012 American Society for Public Administration conference
»Will Parnell and Laure Patrick present "What Role do Recycled Materials Play in Supporting the Creative Capacity of Children?" at The Wonder of Children's Creative Thinking: Inspirations from Reggio Emilia, Italy, symposium
»Gerry Sussman presents "Systemic Propaganda and State Branding in Post-Soviet Eastern Europe" at the Western Political Science Association
»Randall Bluffstone co-authors "Are Soil Conservation Technologies 'Win-Win?' Evidence from the Ethiopian Highlands" in Natural Resources Forum
»Sarah Bunton co-authors "Make the Context Work for You: Faculty in a Changing Academic Medicine Landscape" in Journal of Clinical Psychology
»Chia Yin Hsu, History faculty, authored "Railroad Technocracy, Extraterritoriality, and Imperial Lieux de Mémoire in Russian Émigrés' Manchuria, 1920-1930s" published in Ab Imperio, 4/2011.
»Janet Walker and Celeste Moser author "Does Team-Based Planning Work for Older Adolescents? Findings from Studies of Wraparound" in Psychiatric Rehabilitation Journal
»Erik Bodegom, Ralf Widenhorn, Carl Wamser receive Partners in Science Program grants to bring high school teachers into research labs
»Stefan Talke and Ed Zaron receive Office of Naval Research grant for "Shallow Turbulence in Rivers and Estuaries"
Tuesday, April 3, 2012
Wednesday, April 4, 2012
Thursday, April 5, 2012
»Electrical and Computer Engineering Professor W. Robert Daasch Honored for Length of Service to PSU
Friday, April 6, 2012
»Stefan Talke, CEE Senior Research Associate, Selected by Office of Naval Research for Prestigious Young Investigator Program
Monday, April 9, 2012
»Pat Boas, Art faculty, receives the 21st annual Bonnie Bronson Fellowship Award from Reed College. A public celebration honoring Boas will be held April 18 at the college. The fellowship includes the purchase of six of Boas' works.
»Graduate student Eric Albright and Miguel Figliozzi, Civil and Environmental Engineering faculty, co-author "A Study of the Factors that Influence Transit Signal Priority Effectiveness and Late Bus Recovery at the Signalized Intersection Level" published
»Harrell Fletcher, Art faculty, curates an exhibit, Only Birds Sing the Music of Heaven in this World, at the Museum of Craft and Folk Art, San Francisco, Calif., March 23 - July 7.
»Piman Limpaphayom, Business Administration faculty, presents the keynote talk, "Does Corporate Governance Matter: Evidence from Emerging Markets in Asia" before CFA society of Portland on Feb. 29.
»G.L.A. Harris, Public Administration faculty, presents a paper, "Women and Faculty of Color: Implications for Representation in the Professoriate," as part of the Organizational Culture in the Higher Education Sector: Does the Culture in Higher Education
»Alex Ruzicka and Melinda Hutson, Geology faculty, present "Large, Silica-rich Igneous-Textured Inclusions in the Buzzard Coulee (H4) Chondrite" at the 43rd Lunar and Planetary Science Conference in Houston, March 19-23.
»Christof Teuscher, Electrical and Computer Engineering faculty, presents "From Intrinsic to Designed Computation: Computing Beyond the Boolean and CMOS World" at the Defense Advanced Research Projects Agency/Microsystems Technology Office Unconventional C
»Sarah Bunton, University Studies, co-authors "Research Paradigms in Academic Medicine" published in the Academic Medicine journal, Vol. 87, No. 3, 2012.
»Chia Yin Hsu, History faculty, authors "Railroad Technocracy, Extraterritoriality, and Imperial Lieux de Mémoire in Russian Émigrés' Manchuria, 1920-1930s" published in Ab Imperio, 4/2011.
»Masami Nishishiba, Public Administration faculty, authors "Local Government Diversity Initiatives in Oregon: An Exploratory Study" published in the State and Local Government Review, Vol. 44, No. 1, 2012.
»Dilafruz Williams, Education faculty, authors "4 inches of Soil: Teaching Biodiversity in the Learning Gardens. A Photo-Essay" in the Journal of Sustainability Education, March 2012.
»Kristi Yuthas, Business Administration faculty, co-authors "The Critical Role of Trust in Microfinance Success: Identifying Problems and Solutions" published in the Journal of Developmental Entrepreneurship.
»Kelly Clifton, Civil and Environmental Engineering and Oregon Modeling Collaborative faculty, receives a contract from Parsons Brinckerhoff Americas, Inc., for "Transportation and Land Use Model Integration Program Stage 5 Project."
Tuesday, April 10, 2012
Wednesday, April 11, 2012
Thursday, April 12, 2012
Friday, April 13, 2012
Saturday, April 14, 2012
Monday, April 16, 2012
»Jenny Welnick and Caitlin Anderson elected as state representatives to National Intramural Recreational Sports Association (NIRSA)
»Portland State Campus Rec wins two National Intramural Recreational Sports Association (NIRSA) Creative Excellence awards
»Alex Accetta, Director, of Campus Rec, elected At-Large Director for the National Intramural Recreational Sports Association (NIRSA)
»Deborah Smith Arthur, University Studies faculty, will accept a Multnomah County Volunteer Award for the Juvenile Justice Capstone, which she has taught since 2004, at the Multnomah County Volunteer Awards April 18.
»Jordann Kerns, Student Health and Counseling, is the Oregon Academy of Nutrition and Dietetics 2012 Young Dietitian of the Year. In addition to being a dietitian with Student Health, Kearns does relief work for Providence Hospital and is a Columbia River
»Christof Teuscher, Engineering and Computer Science faculty, has a student, Alireza Goudarzi, whose paper titled "Emergent Criticality through Adaptive Information Processing in Boolean Networks" was published in the prestigious Physical Review Letters jo
»Dacian Daescu, Mathematics and Statistics faculty, presents "Error Covariance Sensitivity and Impact Estimation with Adjoint 4D-Var" to the Society for Industrial and Applied Mathematics Conference on Uncertainty Quantification, April 2-5, in Raleigh, N.C
»Harrell Fletcher, Art faculty, gives lecture for the Visiting Artists Series at Watkins College of Art, Design & Film, in Nashville, Tenn., March 29.
»Juan Manuel Heredia, Architecture faculty, gives keynote titled "Invention of America and its Spatial Manifestations" at an international conference on Architecture and its Geographical Horizons, University of Lincoln, United Kingdom, April 4-5. His lectu
»Karen Haley, Education faculty, presents "Figured Worlds: Connecting Student Affairs and Academic Affairs" at the 2012 annual American College Personnel Association convention in Louisville, Ky.
»Silvia Boero, World Languages and Literatures faculty, presents an essay, "Autobiography and Denunciation in the Post-Unity Polemic: Marchesa Colombi and Anna Franchi," and gives lessons at Laboratoire LLS, Université de Savoie, in Chambery, France, where
»Annabelle Dolidon, World Languages and Literatures faculty, co-authors Tu sais quoi?! Textbook for the French Conversation Class, published by Yale University Press, April 2012.
»Sherril Gelmon, Public Administration faculty, is lead author of "Building Capacity for Community-Engaged Scholarship" in the March 2012 (Volume 16) issue of the Journal of Higher Education Outreach and Engagement. She is a collaborating author on "Facult
»Sean Kohles, Mechanical and Materials Engineering faculty, co-authors an article, "Biokinetic Mechanisms Linked With Musculoskeletal Health Disparities: Stochastic Models Applying Tikhonov's Theorem to Biomolecule Homeostasis," published in the Journal of
»Gerry Sussman, Urban Studies and Planning and International Studies faculty, authors an article, "Branded Versus Organic Democracy," in the March 2012 issue of the European Journal of Communication.
»Peter Veerman, Mathematics and Statistics faculty, co-authors a paper, "Asymptotic Reliability Theory of k-out-of-n Systems," for the Journal of Statistical Planning and Inference. Written with Torrado Robles from Spain, the paper investigates the reliabi
»Miguel Figliozzi and Chris Monsere, Civil and Environmental Engineering faculty, receive a research grant from the Oregon Department of Transportation to work on the "Design and Implementation of Pedestrian and Bicycle-Specific Data Collection Methods in
»Two Students Mentored by ECE Assistant Professor Christof Teuscher Win First Place at 8th Annual Sigma Xi Student Research Symposium
Tuesday, April 17, 2012
Wednesday, April 18, 2012
Thursday, April 19, 2012
»Collaborative project between the Regional Laboratory for the Science of Cultural Heritage Conservation and the Portland Art Museum
Friday, April 20, 2012
Monday, April 23, 2012
»Alex Accetta, Campus Recreation, was elected at-large director for the National Intramural Recreational Sports Association. He will act as a liaison and representative to and for its board of directors, will approve new or revised policies and proposed op
»Jen Armbruster, Jessie Belter, Jenny Welnick, and Tyler Baker, Campus Recreation, present "Balls to Walls: How to Make Your Facilities and Programs Accessible" at the annual National Intramural Recreational Sports Association Conference in Tampa, Florida.
»Jenny Welnick and Caitlin Anderson, Campus Recreation, became the elected state representatives to the National Intramural Recreational Sports Association.
»Christine Cress, Educational Leadership and Policy faculty, and grad student Sarah Drummond Hays present "Assessment for Learning, Action, and Impact: Civic Engagement Data Strategies for Capacity Building" at the Continuums of Service Annual Conference,
»Harrell Fletcher, Art faculty, discusses "The Emergence of Art and Social Practice" at the first Ned Behnke Annual Lecture for the Neddy at Cornish College of the Arts, Seattle, April 18.
»Susan Kirtley, English faculty, presents a paper, "Power, Pedagogy, and Persuasion: Invitational Rhetoric in What It Is," at the joint conference of the American Culture and Popular Culture Associations in Boston.
»Lisa McKinney, Darby Smith, and Errin Beck, Applied Linguistics faculty, present "Orienting New Faculty Adjuncts" and "Customizing Professional Development" at the Teachers of English as a Second or Other Language International Convention, Philadelphia, M
»Janet Walker, Nancy Koroloff, and Celeste Moser, Regional Research Institute and Social Work faculty, present at the 24th Annual Children's Mental Health Research and Policy Conference in Tampa, Fla., March 6. Walker presents an invited plenary session en
»Miguel Figliozzi, Civil and Environmental Engineering faculty, authors "The Time Dependent Vehicle Routing Problem with Time Windows: Benchmark Problems, an Efficient Solution Algorithm, and Solution Characteristics" published in Transportation Research P
»Darrell Grant, Music faculty, performs on piano as a member of The Bridge Quartet to kick off the spring season of PDX Jazz @ The Mission Theater, April 19. The performance was a special tribute to Thelonious Monk titled "Crossing into the Monkasphere."
»Pamela Miller, Social Work faculty, authors a book chapter, "The American Health Care System from a Social (Work) Perspective in Between America and Poland," published in Opole Sociological Studies, Nomos, Krakow, Poland.
»Peter Veerman, Mathematics and Statistics faculty, co-authors a paper, "Asymmetric Decentralized Flocks," for the journal Transactions on Automatic Control. Written with B.D. Stosic from Brazil and F.M. Tangerman from Long Island, the paper discusses a st
»Lawrence Wheeler, University Honors Program faculty, has two original calligraphic works, "Reading Grammatology" and "Mao Speaks Back to Andy," published in the annual international juried issue of Letter Arts Review, Vol. 25, No. 2.
Tuesday, April 24, 2012
Wednesday, April 25, 2012
Thursday, April 26, 2012
Friday, April 27, 2012
»Recent PSU Graduate in Mechanical and Materials Engineering, Joshua Booren, Awarded National Science Foundation Graduate Research Program Fellowship
Monday, April 30, 2012
»Darrell Grant, Music faculty, leads his own jazz music quartet at the Brasserie Montmartre Friday Night Jazz Series in Portland, April 20.
»Ulrich Hardt, Education emeritus faculty, wins a 2012 Oregon Book Award, the Walt Morey Young Readers Literary Legacy Award, for his contributions to the Oregon literary community. As a member and past president of the Oregon Council of Teachers of Englis
»Piman Limpaphayom, Business Administration faculty, gives interview with Willamette Week about issues and considerations in personal finance and investing. The interview was featured in an article entitled "Make the Pie Higher: So You Finally Made Some Mo
»Ken Ruoff, History faculty, wins a 2012 Oregon Book Award, the Frances Fuller Victor Award for General Nonfiction, for his book, Imperial Japan at its Zenith, published by Cornell University Press, explaining how Japan's cult of the emperor fueled support
»Elizabeth Almer, Business Administration faculty, presents a paper entitled "A Model of Individual Faculty Salaries" at the American Accounting Association Western Region Meeting, Vancouver, Wash., April 21.
»Errin Beck, Monika Mulder, and Linnea Spitzer, Applied Linguistics faculty, present "Learner-Centered Classroom Activities for Advanced Academic Writing" at the Teachers of English as a Second or Other Language International Convention, Philadelphia, Marc
»Jill Emery, Library faculty, presents "The Role of the Modern Intermediary and What Constitutes Value in the Library of 2012" at the Association of Subscription Agents & Intermediaries 2012 Conference, London, United Kingdom, Feb. 28.
»Amy Hofer, Library faculty, presents a poster session, "Taking the Library to the LMS: A Collaborative Solution for Online Classrooms," at the 2012 Educause West/Southwest Regional Conference, Portland, Feb. 23.
»Juan Heredia, Architecture faculty, delivers a paper entitled "Chile and Mexico: Antipodal Historiographies, Antipodal Architectures?" at the 65th annual Conference of the Society of Architectural Historians held in Detroit, April 19.
»Anne McClanan, Art faculty, presents an invited lecture, "Horror and the Hunt: Spectacles of Animal Violence in the Late Roman World," at University of Nevada, Reno, in April.
»Anne McClanan, Art faculty, presents an invited lecture, "Horror and the Hunt: Spectacles of Animal Violence in the Late Roman World," at University of Nevada, Reno, in April.
»Gerard Mildner, Business Administration faculty, gives a talk titled "Portland Real Estate Trends" before the Commercial Real Estate Brokers of Metropolitan Portland, April 12.
»Will Parnell, Early Childhood Education faculty, presents a book chapter, "Becoming, Being and Unbecoming an Educator in Early Childhood Education" and signs books at the American Educational Research Association in Vancouver, B.C., April 14.
»Kimberly Pendell and Michael Bowman, Library faculty, present "Usability Testing Library Mobile Websites in a Fragmented Smartphone Market" at the Online Northwest Conference, Corvallis, Feb. 10.
»David Sailor, Mechanical and Materials Engineering faculty, presents "Building Energy Effects of Green Roof Design Decisions" at the Building Enclosure Science and Technology conference BEST3 in Atlanta, April 4.
»Jenny Stenseth, Applied Linguistics faculty, presents "Pronunciation on the Web: An Independent Study Project" at the Teachers of English to Speakers of Other Languages International Convention, Philadelphia, March 28-31.
»Jennifer Tappan, History faculty, presents an invited lecture, "A Healthy Child Comes from A Healthy Mother: Malnutrition and Motherhood in Buganda, 1935-1974," for the African Studies Lecture Series at University of Oregon, Eugene, April 19.
»Sue Taylor, Art History faculty, presents a paper on "The Art and Activism of Hollis Sigler, 1948-2001" in a session on Queer Art at the Northwest Women's Studies Association Conference, hosted by Portland State, April 21.
»Lynn Chmelir, Library faculty and Interim University Librarian, authors an article, "Here Today, Gone Tomorrow: Observations of an Interim Academic Library Director," in the Spring 2012 issue of the Oregon Library Association Quarterly.
»Leni Zumas, English faculty, reads from her forthcoming novel, The Listeners, at the Loggernaut Reading Series, Portland, April 11.
»Paul Collins, English faculty, authors "That's Rich: When Did Executive Pay at Universities Get So High?" published in Slate, March 5.
»Charles Deemer, English adjunct faculty, publishes Varmints, an opera libretto in search of music, as a Kindle book. Round Bend Press will publish a paperback in the fall. This tragi-comedy of the Old West, set in the gold fields of eastern Oregon, is bas
»Meredith Farkas, Library faculty, authors an article, "Participatory Technologies, Pedagogy 2.0 and Information Literacy," published in Library Hi Tech, Vol. 30, Issue 1, 2012.
»Harrell Fletcher, Art faculty, has a major work, The American War, included in a yearlong exhibit, "The Shaping of New Visions: Photography, Film, Photobook," at the Museum of Modern Art in New York City.
»Jeff Fletcher, Systems Science and University Studies faculty, co-authors an article, "Hamilton's Rule in Multi-level Selection Models," published in the April 21 issue of the Journal of Theoretical Biology, Vol. 299.
»Emily Ford, Library faculty, authors a blog post, "Consensus Decision-Making and its Possibilities in Libraries," for the group blog In the Library with the Lead Pipe, Jan. 25.
»Michele Glazer, English faculty, authors a poem, "Wilds," published in the Boston Review, April 2012.
»Jeremy Spoon, Anthropology faculty, authors "Tourism, Persistence, and Change: Sherpa Spirituality and Place in Sagarmatha (Mount Everest) National Park and Buffer Zone, Nepal" published in the Journal of Ecological Anthropology, Vol. 15, No. 1, 2011.
»Tracy Prince, Portland Center for Public Humanities, co-authors "Save the Jantzen Beach Carousel!" for the Portland Architecture blog on April 16, and "Last Ride on Historic Jantzen Beach Carousel April 22" for the Carousel News blog on April 12.
»Alex Ruzicka and Rick Hugo, Geology faculty, receive a $132,000 NASA grant for "Acquisition of an Electron Back Scatter Detector for the Zeiss Sigma SEM at Portland State University."


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Home > News & Events > Wayland Press Release Archives > 2005 News Releases > April 2005 > WBU to present opera scenes
WBU to present opera scenes
PLAINVIEW – The Department of Music at Wayland Baptist University is making final preparations for an evening of scenes from opera, operetta and American musical theatre which will be presented at 7:30 p.m. on April 21-22 in the Miller Recital Hall in Harral Memorial Auditorium.
The program will include operatic scenes from Mozart's The Marriage of Figaro, Don Giovanni, The Magic Flute and Cosi fan tutte (They Are All Like That) and duets and solos from My Fair Lady, Sweeney Todd, West Side Story, Oklahoma and Show Boat. The program will close with the famous "Toast to Love" ensemble from Johann Strauss' popular operetta Die Fledermaus. The program will be directed by Gerald Dolter, visiting professor of voice and accompanied at the piano by WBU Associate Professor of Music Jennie Lynn Hodges.
Members of the cast participate in a bi-weekly class in opera performance practice at Wayland. They range in age from freshman to senior and are all music majors. The class helps the students make the performance transition from the printed musical page to the performance stage. They learn many of the current techniques employed by today's stage professionals in opera and on Broadway. Although the current program has been in rehearsal since January, many of the class members participated in an introductory music theatre acting class in the fall semester of 2004.
The class members include sopranos Leslie Delgado, Amy Moss, Ariel Smeaton, Marta Turpin and Lauren Willson; mezzo sopranos Alicia Alford and Labrina Lang; tenor Jeremy Walker and baritones Jamar Jordan and Grayson Smith.
Admission to the performance is free and open to the public. For more information, contact the Department of Music at 806-291-1060.

subset: commoncrawl


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Resistance 2 "Twisted History" [HD PS3 Video Game Behind The Scenes Story]
Remember to click 'watch in high quality' A look at the history behind the Resistance 2 story. Platforms: Playstation 3 Exclusive Release Date: 04/11/2008
Please click the "Report" button below if the video on this page is not working properly.
Comments will only be displayed by verified emails. No Spamming or Racism.


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Thomas Newman's work for this film...
does make the main impression.
It's not necessary to kill me for these words. Just listen to this very soundtrack yourself.
let me put it like this:
there're several points here:
1) the soundtrack
2) the main personage's performance
3) the plot, which is too much for our dreams, too small for our expectations, and contains in itself an endless story futher to tell for those of us


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If you can meet the above requirements, please contact with us at email@example.com. And we'll email you our bank details. Thank you so much for your understanding!
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Orders will be processed in 1 - 2 working days after we get your order details and payment. For the long-time holiday, we'll post the info on our website and reply you automatically vi emails.
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Items are always shipped via Singapore airmail or registered Singapore airmail. And if you'd like to have fast shipping, you would email us for the extra fast shipping fee at firstname.lastname@example.com.
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Summary: Glutaminase
Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.
This is the Wikipedia entry entitled "Glutaminase". More...
The Wikipedia text that you see displayed here is a download from Wikipedia. This means that the information we display is a copy of the information from the Wikipedia database. The button next to the article title ("Edit Wikipedia article") takes you to the edit page for the article directly within Wikipedia. You should be aware you are not editing our local copy of this information. Any changes that you make to the Wikipedia article will not be displayed here until we next download the article from Wikipedia. We currently download new content on a nightly basis.
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Pfam has chosen to link families to Wikipedia articles. In some case we have created or edited these articles but in many other cases we have not made any direct contribution to the content of the article. The Wikipedia community does monitor edits to try to ensure that (a) the quality of article annotation increases, and (b) vandalism is very quickly dealt with. However, we would like to emphasise that Pfam does not curate the Wikipedia entries and we cannot guarantee the accuracy of the information on the Wikipedia page.
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Glutaminase Edit Wikipedia article
Crystallographic structure of dimeric protein-glutaminase from Chryseobacterium proteolyticum.[1]
|EC number
|CAS number
|IntEnz view
|BRENDA entry
|NiceZyme view
|KEGG entry
|metabolic pathway
|PDB structures
|RCSB PDB PDBe PDBsum
|Gene Ontology
|AmiGO / QuickGO
probable glutaminase from bacillus subtilis complexed with 6-diazo-5-oxo-l-norleucine
|Pfam clan
|1mki / SUPFAM
Glutaminase (EC 18.104.22.168, glutaminase I, L-glutaminase, glutamine aminohydrolase) is an amidohydrolase enzyme that generates glutamate from glutamine. Glutaminase has tissue-specific isoenzymes. Glutaminase has an important role in glial cells.
Glutaminase catalyzes the following reaction:
Glutamine + H2O → glutamate + NH3
Tissue distribution
Glutaminase is expressed and active in periportal hepatocytes, where it generates NH3 (ammonia) for urea synthesis, as does glutamate dehydrogenase.[2] Glutaminase is also expressed in the epithelial cells of the renal tubules, where the produced ammonia is excreted as ammonium ions. This excretion of ammonium ions is an important mechanism of renal acid-base regulation. During chronic acidosis, glutaminase is induced in the kidney, which leads to an increase in the amount of ammonium ions excreted. Glutaminase can also be found in the intestines, whereby hepatic portal ammonia can reach as high as 0.26 mM (compared to an arterial blood ammonia of 0.02 mM).
One of the most important roles of glutaminase is found in the axonal terminals of neurons in the central nervous system. Glutamate is the most abundantly used excitatory neurotransmitter in the CNS. After being released into the synapse for neurotransmission, glutamate is rapidly taken up by nearby astrocytes, which convert it to glutamine. This glutamine is then supplied to the presynaptic terminals of the neurons, where glutaminases convert it back to glutamate for loading into synaptic vesicles. Although both "kidney-type" (GLS1) and "liver-type" (GLS2) glutaminases are expressed in brain, GLS2 has been reported to exist only in cellular nuclei in CNS neurons.[3]
ADP is the strongest adenine nucleotide activator of glutaminase. Studies have also suggested ADP lowered the Km for glutamine and increased the Vmax. They found that these effects were increased even more when ATP was present.[4]
Phosphate-activated mitochondrial glutaminase (GLS1) is suggested to be linked with elevated metabolism, decreased intracellular reactive oxygen species (ROS) levels, and overall decreased DNA oxidation in both normal and stressed cells. It is suggested that GLS1's control of ROS levels facilitates "the ability of p53 to protect cells from accumulation of genomic damage and allows cells to survive after mild and repairable genotoxic stress.â€[5]
The structure of glutaminase has been determined using X-ray diffraction to a resolution of up to 1.73 Ã…. There are 2 chains containing 305 residues that make up the length of this dimeric protein. On each strand, 23% of the amino acid content, or 71 residues, are found in the 8 helices. Twenty-one percent, or 95 residues, make up the 23 beta sheet strands.[1]
Humans express 4 isoforms of glutaminase. GLS encodes 2 types of kidney-type glutaminase with a high activity and low Km. GLS2 encodes 2 forms of liver-type glutaminase with a low activity and allosteric regulation.[2]
Related proteins
Glutaminases belong to a larger family that includes serine-dependent beta-lactamases and penicillin-binding proteins. Many bacteria have two isozymes. This model is based on selected known glutaminases and their homologs within prokaryotes, with the exclusion of highly derived (long-branch) and architecturally varied homologs, so as to achieve conservative assignments. A sharp drop in scores occurs below 250, and cutoffs are set accordingly. The enzyme converts glutamine to glutamate, with the release of ammonia. Members tend to be described as glutaminase A (glsA), where B (glsB) is unknown and may not be homologous (as in Rhizobium etli; some species have two isozymes that may both be designated A (GlsA1 and GlsA2).
Clinical significance
Many cancers rely on glutaminase thus glutaminase inhibitors have been proposed as a cancer treatment.[6][7] As of July 2018[update] some glutaminase inhibitors are in mid-stage clinical trials.
- ^ a b PDB: 3A56; Hashizume R, Mizutani K, Takahashi N, Matsubara H, Matsunaga A, Yamaguchi S, Mikami B (2010). "Crystal structure of protein-glutaminase". doi:10.2210/pdb3a56/pdb. Cite journal requires
- ^ a b Van Noorden, Botman (August 2014). "Determination of Phosphate-activated Glutaminase Activity and Its Kinetics in Mouse Tissues using Metabolic Mapping (Quantitative Enzyme Histochemistry)" (PDF). Journal of Histochemistry & Cytochemistry. 62 (11): 813–26. doi:10.1369/0022155414551177. PMC 4230542. PMID 25163927. Retrieved 26 September 2014.
- ^ Olalla L, Gutiérrez A, Campos JA, Khan ZU, Alonso FJ, Segura JA, Márquez J, Aledo JC (Aug 2002). "Nuclear localization of L-type glutaminase in mammalian brain". J. Biol. Chem. 277 (41): 38939–38944. doi:10.1074/jbc.C200373200. PMID 12163477.
- ^ Masola B, Ngubane NP (December 2010). "The activity of phosphate-dependent glutaminase from the rat small intestine is modulated by ADP and is dependent on integrity of mitochondria". Arch. Biochem. Biophys. 504 (2): 197–203. doi:10.1016/j.abb.2010.09.002. PMID 20831857.
- ^ Suzuki S, Tanaka T, Poyurovsky MV, Nagano H, Mayama T, Ohkubo S, Lokshin M, Hosokawa H, Nakayama T, Suzuki Y, Sugano S, Sato E, Nagao T, Yokote K, Tatsuno I, Prives C (April 2010). "Phosphate-activated glutaminase (GLS1), a p53-inducible regulator of glutamine metabolism and reactive oxygen species". Proc. Natl. Acad. Sci. U.S.A. 107 (16): 7461–6. doi:10.1073/pnas.1002459107. PMC 2867754. PMID 20351271.
- ^ Chen, L; Cui, H (2015). "Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach". International Journal of Molecular Sciences. 16 (9): 22830–55. doi:10.3390/ijms160922830. PMC 4613338. PMID 26402672.
- ^ Sheikh, T. N; Patwardhan, P. P; Cremers, S; Schwartz, G. K (2017). "Targeted inhibition of glutaminase as a potential new approach for the treatment of NF1 associated soft tissue malignancies". Oncotarget. 8 (55): 94054–94068. doi:10.18632/oncotarget.21573. PMC 5706855. PMID 29212209.
External links
- Glutaminase at the US National Library of Medicine Medical Subject Headings (MeSH)
- Research information on glutaminase (WikiGenes)
This page is based on a Wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.
This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.
Glutaminase Provide feedback
This family of enzymes deaminates glutamine to glutamate EC:188.8.131.52.
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR015868
Glutaminases (EC) deaminate glutamine to glutamate. In Bacillus subtilis, glutaminase is encoded by glnA, which is part of an operon, glnA-glnT (formerly ybgJ-ybgH), where glnT encodes a glutamine transporter. The glnA-glnT operon is regulated by the 2-component system GlnK-GlnL in response to glutamine [PUBMED:15995196]. This entry represents the core structural motif of a family of glutaminases that include GlnA, which are characterised by their beta-lactamase-like topology, containing a cluster of alpha-helices and an alpha/beta sandwich.
This family describes the enzyme glutaminase, from a larger family that includes serine-dependent beta-lactamases and penicillin-binding proteins. Many bacteria have two isozymes. This model is based on selected known glutaminases and their homologues within prokaryotes, with the exclusion of highly-derived (long branch) and architecturally varied homologues, so as to achieve conservative assignments. A sharp drop in scores occurs below 250, and cutoffs are set accordingly. The enzyme converts glutamine to glutamate, with the release of ammonia. Members tend to be described as glutaminase A (glsA), where B (glsB) is unknown and may not be homologous (as in Rhizobium etli. Some species have two isozymes that may both be designated A (GlsA1 and GlsA2).
Gene Ontology
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function
|glutaminase activity (GO:0004359)
|Biological process
|glutamine metabolic process (GO:0006541)
Domain organisation
Below is a listing of the unique domain organisations or architectures in which this domain is found. More...
The graphic that is shown by default represents the longest sequence with a given architecture. Each row contains the following information:
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- a link to the page in the Pfam site showing information about the sequence that the graphic describes
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
Note that you can see the family page for a particular domain by clicking on the graphic. You can also choose to see all sequences which have a given architecture by clicking on the Show link in each row.
Finally, because some families can be found in a very large number of architectures, we load only the first fifty architectures by default. If you want to see more architectures, click the button at the bottom of the page to load the next set.
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Pfam Clan
This family is a member of clan Beta-lactamase (CL0013), which has the following description:
This superfamily contains proteins that have a beta-lactamase fold. This includes beta-lactamases as well as Dala-Dala carboxypeptidases and glutaminases.
The clan contains the following 6 members:Beta-lactamase Beta-lactamase2 Glutaminase Peptidase_S11 Peptidase_S13 Transpeptidase
We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets, the UniProtKB sequence database, the NCBI sequence database, and our metagenomics sequence database. More...
There are various ways to view or download the sequence alignments that we store. We provide several sequence viewers and a plain-text Stockholm-format file for download.
Alignment types
We make a range of alignments for each Pfam-A family:
- seed
- the curated alignment from which the HMM for the family is built
- full
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- UniProt
- alignment generated by searching the UniProtKB sequence database using the family HMM
- alignment generated by searching the NCBI sequence database using the family HMM
- meta
- alignment generated by searching the metagenomics sequence database using the family HMM
You can see the alignments as HTML or in three different sequence viewers:
- jalview
- a Java applet developed at the University of Dundee. You will need Java installed before running jalview
- an HTML page showing the whole alignment.Please note: full Pfam alignments can be very large. These HTML views are extremely large and often cause problems for browsers. Please use either jalview or the Pfam viewer if you have trouble viewing the HTML version
- PP/Heatmap
- an HTML-based representation of the alignment, coloured according to the posterior-probability (PP) values from the HMM. As for the standard HTML view, heatmap alignments can also be very large and slow to render.
You can download (or view in your browser) a text representation of a Pfam alignment in various formats:
- Selex
- Stockholm
You can also change the order in which sequences are listed in the alignment, change how insertions are represented, alter the characters that are used to represent gaps in sequences and, finally, choose whether to download the alignment or to view it in your browser directly.
You may find that large alignments cause problems for the viewers and the reformatting tool, so we also provide all alignments in Stockholm format. You can download either the plain text alignment, or a gzipped version of it.
View options
We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.
|Representative proteomes
1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
Format an alignment
Download options
We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.
|Representative proteomes
|Raw Stockholm
You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.
HMM logo
HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...
If you find these logos useful in your own work, please consider citing the following article:
This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.
Note: You can also download the data file for the tree.
Curation and family details
This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.
|Seed source:
|Previous IDs:
|Sequence Ontology:
|Bateman A
|Number in seed:
|Number in full:
|Average length of the domain:
|268.40 aa
|Average identity of full alignment:
|40 %
|Average coverage of the sequence by the domain:
|68.93 %
HMM information
|HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
|Model details:
|Model length:
|Family (HMM) version:
|download the raw HMM for this family
Species distribution
Sunburst controlsHide
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|Other sequences
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This visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...
This chart is a modified "sunburst" visualisation of the species tree for this family. It shows each node in the tree as a separate arc, arranged radially with the superkingdoms at the centre and the species arrayed around the outermost ring.
How the sunburst is generated
The tree is built by considering the taxonomic lineage of each sequence that has a match to this family. For each node in the resulting tree, we draw an arc in the sunburst. The radius of the arc, its distance from the root node at the centre of the sunburst, shows the taxonomic level ("superkingdom", "kingdom", etc). The length of the arc represents either the number of sequences represented at a given level, or the number of species that are found beneath the node in the tree. The weighting scheme can be changed using the sunburst controls.
In order to reduce the complexity of the representation, we reduce the number of taxonomic levels that we show. We consider only the following eight major taxonomic levels:
- superkingdom
- kingdom
- phylum
- class
- order
- family
- genus
- species
Colouring and labels
Segments of the tree are coloured approximately according to their superkingdom. For example, archeal branches are coloured with shades of orange, eukaryotes in shades of purple, etc. The colour assignments are shown under the sunburst controls. Where space allows, the name of the taxonomic level will be written on the arc itself.
As you move your mouse across the sunburst, the current node will be highlighted. In the top section of the controls panel we show a summary of the lineage of the currently highlighed node. If you pause over an arc, a tooltip will be shown, giving the name of the taxonomic level in the title and a summary of the number of sequences and species below that node in the tree.
Anomalies in the taxonomy tree
There are some situations that the sunburst tree cannot easily handle and for which we have work-arounds in place.
Missing taxonomic levels
Some species in the taxonomic tree may not have one or more of the main eight levels that we display. For example, Bos taurus is not assigned an order in the NCBI taxonomic tree. In such cases we mark the omitted level with, for example, "No order", in both the tooltip and the lineage summary.
Unmapped species names
The tree is built by looking at each sequence in the full alignment for the family. We take the name of the species given by UniProt and try to map that to the full taxonomic tree from NCBI. In some cases, the name chosen by UniProt does not map to any node in the NCBI tree, perhaps because the chosen name is listed as a synonym or a misspelling in the NCBI taxonomy.
So that these nodes are not simply omitted from the sunburst tree, we group them together in a separate branch (or segment of the sunburst tree). Since we cannot determine the lineage for these unmapped species, we show all levels between the superkingdom and the species as "uncategorised".
Since we reduce the species tree to only the eight main taxonomic levels, sequences that are mapped to the sub-species level in the tree would not normally be shown. Rather than leave out these species, we map them instead to their parent species. So, for example, for sequences belonging to one of the Vibrio cholerae sub-species in the NCBI taxonomy, we show them instead as belonging to the species Vibrio cholerae.
Too many species/sequences
For large species trees, you may see blank regions in the outer layers of the sunburst. These occur when there are large numbers of arcs to be drawn in a small space. If an arc is less than approximately one pixel wide, it will not be drawn and the space will be left blank. You may still be able to get some information about the species in that region by moving your mouse across the area, but since each arc will be very small, it will be difficult to accurately locate a particular species.
Tree controlsHide
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Selected sequences
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- graphically
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The tree shows the occurrence of this domain across different species. More...
Species trees
We show the species tree in one of two ways. For smaller trees we try to show an interactive representation, which allows you to select specific nodes in the tree and view them as an alignment or as a set of Pfam domain graphics.
Unfortunately we have found that there are problems viewing the interactive tree when the it becomes larger than a certain limit. Furthermore, we have found that Internet Explorer can become unresponsive when viewing some trees, regardless of their size. We therefore show a text representation of the species tree when the size is above a certain limit or if you are using Internet Explorer to view the site.
If you are using IE you can still load the interactive tree by clicking the "Generate interactive tree" button, but please be aware of the potential problems that the interactive species tree can cause.
Interactive tree
For all of the domain matches in a full alignment, we count the number that are found on all sequences in the alignment. This total is shown in the purple box.
We also count the number of unique sequences on which each domain is found, which is shown in green. Note that a domain may appear multiple times on the same sequence, leading to the difference between these two numbers.
Finally, we group sequences from the same organism according to the NCBI code that is assigned by UniProt, allowing us to count the number of distinct sequences on which the domain is found. This value is shown in the pink boxes.
We use the NCBI species tree to group organisms according to their taxonomy and this forms the structure of the displayed tree. Note that in some cases the trees are too large (have too many nodes) to allow us to build an interactive tree, but in most cases you can still view the tree in a plain text, non-interactive representation. Those species which are represented in the seed alignment for this domain are highlighted.
You can use the tree controls to manipulate how the interactive tree is displayed:
- show/hide the summary boxes
- highlight species that are represented in the seed alignment
- expand/collapse the tree or expand it to a given depth
- select a sub-tree or a set of species within the tree and view them graphically or as an alignment
- save a plain text representation of the tree
Please note: for large trees this can take some time. While the tree is loading, you can safely switch away from this tab but if you browse away from the family page entirely, the tree will not be loaded.
There is 1 interaction for this family. More...
We determine these interactions using iPfam, which considers the interactions between residues in three-dimensional protein structures and maps those interactions back to Pfam families. You can find more information about the iPfam algorithm in the journal article that accompanies the website.
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Glutaminase domain has been found. There are 106 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.
Loading structure mapping...


text:
AMSTUD 121Z: Political Power in American Cities (POLISCI 121, PUBLPOL 133, URBANST 111)
The major actors, institutions, processes, and policies of sub-state government in the U.S., emphasizing city general-purpose governments through a comparative examination of historical and contemporary politics. Issues related to federalism, representation, voting, race, poverty, housing, and finances. Political Science majors taking this course to fulfill the WIM requirement should enroll in POLISCI 121.
Last offered: Winter 2019 | UG Reqs: GER:DB-SocSci, WAY-SI
AMSTUD 122D: Free Speech and Inclusion on Campus (SOC 122D)
How do we balance norms of inclusion and respect with norms of free speech? This seminar course utilizes readings from sociology, political science, and legal/ethical reasoning to elucidate the larger structures and ideals that are at stake in the debates over what kind of speech is tolerable, or more normatively speaking, desirable, at colleges and universities. The expected learning outcomes are: a greater understanding of the free speech's role in American society and democracy, how America's position on free speech compares to other countries, and how speech restriction and liberties can reveal larger patterns in social structure and agency. Finally, key skills students will develop are learning how to identify common ethical frameworks that academic and popular authors use and how to analyze the origins of and changes in social institutions and social structures.
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AMSTUD 123X: Introduction to American Politics and Policy: The Good, The Bad, and The Ugly (POLISCI 102, PUBLPOL 101, PUBLPOL 201)
This is a course about American politics, which means this is a course about individuals, identities, and institutions. How do Americans come to think andnreason about politics? What is the role that identities play in affecting the political judgments that individuals make? How do our political institutionsnrespond to the demands of a diverse public that disagrees about issues related to race and justice, income and wealth inequality, climate change, gunncontrol, reproductive rights, the power of the executive, and the role that government ought to play in the lives of the governed? And how do we makensense of this seemingly peculiar contemporary moment in American politics? These are not easy questions, but they are ones for which political sciencenprovides a useful foundation to guide our inquiry. The objective of this course is to introduce students to various concepts and theoretical frameworks thatnhelp us understand the messiness and complexity of American politics. In addition to classroom lectures and discussion sections, students will benrequired to apply concepts and theoretical frameworks to contemporary issues in American politics. Undergraduate Public Policy students are required to enroll in this class for 5 units.
Terms: Spr | Units: 4-5 | UG Reqs: GER:DB-SocSci, WAY-SI
Instructors: Jefferson, H. (PI) ; Aldridge, A. (TA) ; Johnson, J. (TA) ; Parker, B. (TA)
2019-2020 Spring
4-5 units |
UG Reqs: GER:DB-SocSci, WAY-SI |
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Grading: Satisfactory/Unsatisfactory Exception |
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AMSTUD 124A: The American West (ARTHIST 152, ENGLISH 124, HISTORY 151, POLISCI 124A)
The American West is characterized by frontier mythology, vast distances, marked aridity, and unique political and economic characteristics. This course integrates several disciplinary perspectives into a comprehensive examination of Western North America: its history, physical geography, climate, literature, art, film, institutions, politics, demography, economy, and continuing policy challenges. Students examine themes fundamental to understanding the region: time, space, water, peoples, and boom and bust cycles.
Terms: Spr | Units: 5 | UG Reqs: GER:DB-Hum, GER:EC-AmerCul, WAY-A-II, WAY-SI
Instructors: Cain, B. (PI) ; Fishkin, S. (PI) ; Freyberg, D. (PI) ... more instructors for AMSTUD 124A »
Instructors: Cain, B. (PI) ; Fishkin, S. (PI) ; Freyberg, D. (PI) ; Kennedy, D. (PI) ; Nemerov, A. (PI) ; Petrov, P. (TA)
2019-2020 Spring
5 units |
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| Students enrolled: 34
03/30/2020 - 06/03/2020 Tue, Thu 10:30 AM - 12:20 PM at 200-002 with Cain, B. (PI); Fishkin, S. (PI); Freyberg, D. (PI); Kennedy, D. (PI); Nemerov, A. (PI); Petrov, P. (TA)
Instructors: Cain, B. (PI); Fishkin, S. (PI); Freyberg, D. (PI); Kennedy, D. (PI); Nemerov, A. (PI); Petrov, P. (TA)
UG Reqs: GER:DB-Hum, GER:EC-AmerCul, WAY-A-II, WAY-SI |
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AMSTUD 125: Perspectives on American Journalism (COMM 125, COMM 225)
An examination of American journalism, focusing on how news is produced, distributed, and financially supported. Emphasis on current media controversies and puzzles, and on designing innovations in discovering and telling stories. (Graduate students register for COMM 225.)
Terms: Aut | Units: 4-5 | UG Reqs: GER:DB-SocSci, WAY-SI
Instructors: Hamilton, J. (PI)
2019-2020 Autumn
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Grading: Letter (ABCD/NP) |
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09/23/2019 - 12/06/2019 Tue 12:00 PM - 1:20 PM at 200-205 with Hamilton, J. (PI)
09/23/2019 - 12/06/2019 Thu 12:00 PM - 1:20 PM at School of Education 206 with Hamilton, J. (PI)
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Axess Enrollment will open for students on August 1st.
AMSTUD 130A: In Sickness and In Health: Medicine and Society in the United States: 1800-Present
Explores the history of medical institutions, ideas and practices in the United States from the early nineteenth century to the present. How are ideas of illness and health historically rooted and socially constructed? How did scientific and medical discoveries lead to the rise of scientific medicine, and how were these innovations adopted within the American cultural landscape? Topics include the transformation of therapeutics and technologies, medicine and the scientific ideal in the U.S., gender and race and medicine, the history of public health, and the professionalization and specialization of American medical practice.
Last offered: Autumn 2017 | UG Reqs: GER:DB-SocSci, WAY-SI
AMSTUD 131: Food and American Culture
This course introduces students to the cultural history, politics, and aesthetics of eating in America, exploring topics that have fueled debates about what Americans should eat over the last hundred years. Discussions of American cuisine will lead directly into larger concepts of American identity, culture, and politics. We will ask questions such as: What role does food play in national identity? Have restaurants shaped American social life? What is modern American cuisine?nnCourse goals include fluency in the key terminology and theoretical frameworks of American Studies and a deep historical understanding of our contemporary food system. Students will actively engage with primary sources, including nutrition manuals, advertisements, cookbooks, restaurant menus, and paintings.
Last offered: Spring 2019 | UG Reqs: WAY-SI
AMSTUD 135: Deliberative Democracy and its Critics (COMM 135, COMM 235, COMM 335, ETHICSOC 135F, POLISCI 234P, POLISCI 334P)
This course examines the theory and practice of deliberative democracy and engages both in a dialogue with critics. Can a democracy which emphasizes people thinking and talking together on the basis of good information be made practical in the modern age? What kinds of distortions arise when people try to discuss politics or policy together? The course draws on ideas of deliberation from Madison and Mill to Rawls and Habermas as well as criticisms from the jury literature, from the psychology of group processes and from the most recent normative and empirical literature on deliberative forums. Deliberative Polling, its applications, defenders and critics, both normative and empirical, will provide a key case for discussion.
Terms: Win | Units: 3-5 | UG Reqs: WAY-ER, WAY-SI
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2019-2020 Winter
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UG Reqs: WAY-ER, WAY-SI |
Class #
Section 01 |
Grading: Letter or Credit/No Credit |
| Students enrolled: 3
01/06/2020 - 03/13/2020 Tue 3:00 PM - 5:50 PM at 120-101 with Fishkin, J. (PI); Chang, S. (TA)
Instructors: Fishkin, J. (PI); Chang, S. (TA)
AMSTUD 137: The Dialogue of Democracy (COMM 137W, COMM 237, POLISCI 232T, POLISCI 332T)
All forms of democracy require some kind of communication so people can be aware of issues and make decisions. This course looks at competing visions of what democracy should be and different notions of the role of dialogue in a democracy. Is it just campaigning or does it include deliberation? Small scale discussions or sound bites on television? Or social media? What is the role of technology in changing our democratic practices, to mobilize, to persuade, to solve public problems? This course will include readings from political theory about democratic ideals - from the American founders to J.S. Mill and the Progressives to Joseph Schumpeter and modern writers skeptical of the public will. It will also include contemporary examinations of the media and the internet to see how those practices are changing and how the ideals can or cannot be realized.
Last offered: Spring 2019 | UG Reqs: GER:EC-EthicReas, WAY-ER, WAY-SI
AMSTUD 145: Silicon Valley
Silicon Valley. The site and source of vibrant economic growth and technological innovation. A disruptive force in social, economic, and political systems. An interface between technology and academia, with the the quirky influence of the counterculture in the background. A surprisingly agile cultural behemoth that has reshaped human relationships and hierarchies of all sorts. A brotopia built on the preferences and predilections of rich, geeky white guys. A location with perpetually sunny skies and easy access to beaches and mountains. nnThis seminar will unpack the myths surrounding Silicon Valley by exploring the people, places, industries, and ideas that have shaped it from post-WWII to the present. It takes an interdisciplinary approach to the subject and considers region's history and development; the products of Silicon Valley, from computers and circuit boards to search algorithms and social networks; and Silicon Valley's depictions in photography, film, television, and literature.
Terms: Win | Units: 5 | UG Reqs: WAY-A-II, WAY-SI
Instructors: Kessler, E. (PI)
2019-2020 Winter
5 units |
UG Reqs: WAY-A-II, WAY-SI |
Class #
Section 01 |
Grading: Letter or Credit/No Credit |
| Students enrolled: 15 / 16
01/06/2020 - 03/13/2020 Tue, Thu 10:30 AM - 11:50 AM at School of Education 208 with Kessler, E. (PI)
Instructors: Kessler, E. (PI)
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Residency Program
Our residency is a traditional three-year structured program in clinical dermatology. We encourage clinical research. The Department of Dermatology opened in 1977. Since its inception, we have accepted about two residents a year.
Wright State University Boonshoft School of Medicine is a community-based program, i.e., there is no single university hospital. Similarly, our dermatology residents train at multiple sites, with two main patient care settings. Our residents participate in continuity clinics at our practice site at the Wright State Physicians medical office building on the Wright State University campus and at the Dayton VA Medical Center. We have inpatient consults at Miami Valley Hospital.
Residents work with four fellowship-trained dermatopathologists and two fellowship-trained dermotologic surgeons in each year of training. In addition, residents have a didactic schedule that includes weekly dermatopathology lectures, a comprehensive visiting lecturer program, journal clubs, surgical lectures, kodachrome sessions, monthly Grand Rounds and board review sessions.
Primary practice sites
- Wright State Physicians Dermatology
Dayton Office
725 University Blvd.
Dayton, OH 45435
- Dayton Veterans Affairs Medical Center
4100 West Third Street
Dayton, OH 45428
- Wright State Physicians Dermatology
Springboro Office
SureCare Medical Center
360 West Central Ave.
State Route 73
Springboro, OH 45066
- Private Practice Settings
Applicant tips
We are looking for bright, energetic, motivated individuals who love to work hard, work as a team and want to learn. Our intention is to train future leaders in dermatology. We want people who expect nothing but excellence from themselves and those around them.
We will never discriminate against applicants who have performed prior residencies. We also will not discriminate against outstanding candidates who have trained overseas or at osteopathic medical schools.
Applications for 2018
We will accept two residents for a start date of July 1, 2019. To be considered for the 2018 program, applicants must apply through the Electronic Residency Application Service (ERAS). The deadline for completing your application is October 31, 2017. Applications not completed by that date will not be considered. Applicants selected for interview will be offered a choice of two interview dates with one date being in December 2017 and the other in January 2018.
Applicants who have not yet completed an internship are encouraged to consider and apply for the transitional year offered by the Kettering Medical Center (KMC). Matching with KMC is not a requirement for acceptance to our residency. For an overview of that program, visit the Kettering Medical Center Transitional Year Program web site.


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Sun 8 Mar 2015
DOIs, The Winnower, and Open the Echo Chamber
Posted by Ed under Academia, research
[2] Comments
I've been writing here on Open the Echo Chamber since July of 2010. Good lord, that is a long time. I've cranked out well over 250,000 words on the site (plus or minus 30 articles, or about three books, worth of writing). And for all of that effort, I have received exactly no credit at all for this in my academic job. In my annual reviews and promotion packets, I can shove this work under "service", but 1) most of my colleagues probably wouldn't agree with that categorization and 2) nobody in academia gets much of anything for their service contributions unless they are a full-on administrator. I don't blog for my academic career, I blog as a means of getting ideas outside the rigidity of the peer-review publishing world, the ways it gates off knowledge from those that might use it, and the ways it can police away innovative new thought that challenges existing powers. So, when I recently stumbled across The Winnower, I got excited. "Publish my posts with review and a DOI?" I thought. "Make my posts citable in major journals and technical reports?" I chortled. "Further blur the lines between my academic publishing and the stuff I do on this blog?" I fairly giggled. Yeah, I need to give this a try.
Let me explain:
According to the lovely people at Google Analytics, in that time nearly 50,000 users have committed to over 100,000 pageviews. For a blog that is home to some long, wonky posts, that is pretty amazing. Readership comes from all over the world, with the top 10 countries looking like this:
- United States 37,530(52.18%)
- United Kingdom 7,990(11.11%)
- Canada 4,186(5.82%)
- Australia 1,949(2.71%)
- India 1,339(1.86%)
- Germany 1,019(1.42%)
- Netherlands 834(1.16%)
- Kenya 773(1.07%)
- Philippines 722 (1.00%)
- France 695 (.97%)
It is remarkable that Google lists visitors from 192 different countries and territories. And when you drill down to cities, it gets pretty cool as well:
- Washington 5,023(6.98%)
- London 3,419(4.75%)
- New York 2,965(4.12%)
- Columbia 2,326(3.23%)
- Irmo 1,273(1.77%)
- Toronto 769(1.07%)
- Seattle 713(0.99%)
- Fonthill 676(0.94%)
- Melbourne 642(0.89%)
- Nairobi 604(0.84%)
- Sydney 532(0.74%)
- Cambridge MA 517(0.72%)
- Oxford 500(0.70%)
- Ottawa 466(0.65%)
- San Francisco 459(0.64%)
- Arlington 457(0.64%)
- Chicago 429(0.60%)
- Durham 393(0.55%)
- Boston 367(0.51%)
- Montreal 364(0.51%)
I've known who I was reaching for a while – I get informal notes and phone calls from people at various institutions letting me know they liked (mostly) or disliked/had issues with (sometimes) things I have written. Compared to many blogs, I don't get that many readers. But my readers are my target audience – they are the folks who work in development and climate change. Well, that, and my students here at the University of South Carolina (hence the Columbia and Irmo numbers).
The one big problem for me, and this blog, has been the level of effort it requires, and the ways in which it could (and could not) be used in my primary sectors of employment, academia and development consulting. Though the world is changing fast, the fact is most people still will not take a blog post as seriously as an academic article. That is probably a good thing – there is a lot of crap out on blogs. At the same time, there are really good blogs out there, some of which produce better work/scholarship than you find in the peer-reviewed literature. Finding ways to help people sort out what is good and what is crap, and finding ways to make social media/blog posts viable sources for academic and consulting work, is important to me.
So, starting today, I have linked this blog to The Winnower. When I produce a post with enough intellectual content, I will cross-post it to the Winnower, where it will be subject to a review process, after which it will receive a DOI, making it a real publication in the eyes of many journals and other sources (hell, it will fit under "other academic contributions" on my CV, so there). I'm excited about what The Winnower is trying to do (as you might already know I find academic publishing structures deeply frustrating: just look here, here, here, and here), and if my work serves to further their mission, and their efforts serve to further blur the lines between the ways in which I disseminate my work, I'm happy to give it a go.
Here is my author page at The Winnower. I've currently got six old posts up for review – six posts that were viewed by an average of well over a thousand readers each. So I know you all care about these posts and topics. Go ahead and review them, comment on them, help me make them better…and help The Winnower succeed.
Welcome to the future. Maybe.
2 Responses to " DOIs, The Winnower, and Open the Echo Chamber "
Good luck at The Winnower, Ed.
I had a look. Easy to comment on articles. But 1) If you use their search function, your name, Edward Carr, does not come up. They also do not have an user friendly author page. 2) Then, on setting up an account, I discovered I was given a "WOrdpress key" . I though it would be simple to use this to transfer across my own academic blogs. Sadly no – there is no information on the Winnower or on WordPress on how to use this key. On WordPress, it only tells yo uhow to copy to another one of your own blogs. In the absence of using that key, they say you have to upload an .htm file with the images loaded separately. Not a Word file. I suspect for many people like me, with only an Office suite on their computer (Word makes bad html) this will be an impediment. So how did you do it?


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We are now well into the era in which multicore processors are commonplace, not just in servers, but also in mobile devices, laptops, and PCs. Intel processors are, increasingly, multicore in nature, offering users benefits such as improved application performance, usability, power reduction, and more. To help developers write code for these systems, Intel has worked to develop standards such as OpenMP and MPI. At the same time, Intel is offering new products for parallel programming, based on the new programming model called Intel Parallel Building Blocks (Intel PBB). Intel PBB currently consists of the following three components:
- Cilk Plus: This is a language extension that provides both task and data parallelism constructs. It is currently implemented and supported in Intel C++ Compiler. This article provides an introduction to Cilk Plus.
- Intel Threading Building Blocks (Intel TBB): Intel TBB provides both low-level tasking primitives and high-level parallel algorithms. Intel TBB is implemented as a compiler-independent template library for C++. It is available as a supported product and as open source.
- Intel Array Building Blocks (Intel ArBB): Intel ArBB is a C++ library that provides a generalized vector parallel programming solution that frees application developers from dependencies on particular low-level parallelism mechanisms or hardware architectures. It is currently available in beta-test form.
Programmer Focus
The processor architecture provides multiple parallel resources, including multiple cores, vectors, hyper-threading, and caches. Different programmers have different levels of interest in writing code to take advantage of these resources. Intel PBB, and in particular Cilk Plus, support two approaches. First, programmers may choose to explicitly describe the parallel work at the core level, using tasks, and within each task write explicit vector-level parallelism. Or programmers can let their compiler and system software figure out how processing should be done. This second approach assumes that the work to be done in parallel is clearly defined and that the data on which the work will be done is clearly identified.
In addition to utilization of HW resources, a central part of value added by Intel PBB in general, and by Cilk Plus in particular, has to do with "composability." Many applications are composed of independently written components, which can be homegrown or come from third parties (such as libraries). Typically, the components (and their designers) communicate with each other through higher-level interfaces rather than at a lower, implementation-oriented level. To allow that level of collaboration in a parallel program, the task scheduler has to allow composability (that is, when modules are combined to form the application, they continue to work and perform well).
How does Cilk Plus support composability? The Cilk Plus language, as well as the other components of Intel PBB, utilize work-stealing task schedulers. Work stealing is a task-scheduling technique that is characterized by a mechanism in which units of work can migrate from the worker that generates them to another worker that will execute them if the second worker has no work of its own to process. A worker that runs out of work steals work from a victim that has a queue of work items. In contrast, there is no mechanism by which a worker that encounters opportunities for parallel work can delegate that work to other workers. The precise details of the scheduling mechanism are out of the scope of this article, which focuses on the language aspects. However, the work-stealing technique is at the heart of the composability property, which allows for modular implementation of parallel programs.
Task Parallelism with Cilk Plus
The Cilk Plus language provides two constructs for task level parallelism. The first includes two keywords:
_Cilk_spawn and
_Cilk_ sync. Listings One and Two compare an implementation of the recursive implementation of the well-known Fibonacci code in serial C against a parallel implementation, which was derived from the serial code by adding the new keywords:
Listing One: Serial implementation of Fibonacci code.
int fib (int n) { if (n <= 2) return n; else { int x, y; x = fib(n-1); y = fib(n-2); return x+y; } }
Listing Two: The same code made parallel using Cilk Plus keywords. )Note that no code was changed. Only the Cilk Plus keywords were inserted.)
int fib (int n) { if (N <= 2) return n; else { int x, y; x = _Cilk_spawn fib(n-1); y = fib(n-2); _Cilk_sync; return x+y; } }
Notice that the addition of the keywords is nonintrusive. Changing the serial program to a parallel program only requires insertion of the keywords as appropriate. It does not require changes to the underlying program. The insertion also does not impact the readability and maintainability of the program. The original serial code is easy to see and the program logic is as evident as in the original. This observation highlights one of the main design principles of Cilk Plus: It is designed for parallelizing existing serial C/C++ code. Thus, a benefit of Cilk Plus is the ability it gives developers to easily add parallelism to code by making minimal changes, while providing strong guarantees for serial equivalence.
_Cilk_spawn Keyword
Let us now take a closer look at the
_Cilk_spawn keyword, which applies to a function call, such as
fib(n-1) in Listing Twp. It means that the spawned function can execute concurrently with the remainder of the enclosing function (
fib(n) in this example). The enclosing function is termed a "spawning function" or the parent, and the function being spawned is the child. The
_Cilk_sync keyword means that the parent has to wait until all child tasks return control to the parent.
Note that this mechanism reuses the concept of a function, which is a well-understood concept in C/C++ programming, both as a parallel region (on the parent side) and as the unit that can be spawned (on the child side). Both of these serve the purpose of bringing parallelism to existing programs with minimal effort. The reuse as a parallel region alleviates the need to introduce a new syntactic construct that would serve as a parallel region. The reuse of a function as the unit defining what can be spawned may be viewed as a limitation. In parallelizing an existing program, the programmer may want to indicate that a smaller lexical scope, such as a statement or a loop, can execute concurrently with another statement.
However, by using functions as a spawn unit, the data model remains well understood to the programmer and the language extensions do not have to introduce new rules, which have the potential to introduce programming errors. In the current model, it is clear to the programmer which variables are in the scope of the spawning functions, which variables belong to the child function, and how arguments are being passed. Indeed, argument passing is very much conformant to the way it is done in the underlying language. The values of the arguments are being evaluated by the parent task before detaching the child and enabling concurrency. In the
fib(n-1) example in Listing Two, the value of
n-1 is computed by the parent before the child is spawned. A less trivial example can be observed in Listing Three, where the computation of the arguments is more involved.
Listing Three: A less trivial example of
Val = _Cilk_spawn f(g(x),h(y));
The arguments to the function
f() in Listing Three are themselves function calls. If the operation of
_Cilk_spawn applied to the whole expression, then
g() and
h() might have been allowed to execute concurrently with respect to each other, as well as with respect to the spawning function.
In a case of a data race between the code within the function
g() and
h(), there is no place to insert a synchronization directive.
Arguably, the most important attribute in the behavior of
_Cilk_spawn, in support of equivalence to serial execution, relates to the asymmetry between the two parts of the parent at a
_Cilk_spawn point. A
_Cilk_spawn does not enforce parallel execution, but instead provides an opportunity for parallel execution. The worker whose execution reached the
_Cilk_spawn keyword will continue processing one of the two branches identified by the keyword, while the remaining branch is detached and put in a queue for later execution. As described earlier, the work item in the queue may or may not be picked up for execution by another worker executing on another core.


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'Sharknado' could really happen along Gulf coast – here's how
Think the premise of "Sharknado" and it's new NYC-based sequel sounds a little far-fetched?
Well, get your chainsaw ready and think again.
Earlier this summer, scientists studying the Gulf of Mexico found that sharks were drawn to the warm waters and low pressures often linked to hurricanes. In fact, their swarming around such conditions is so commonplace, the behavior can be used to predict and track hurricanes. In the "Sharknado" movie, an array of shark species are brought ashore by an intense hurricane and flung at the innocent masses by the tornadoes spun from the storm.
Maybe. If a summer filled with shark activity in the Gulf is any indication, these fishy fiends could just be waiting for the right opportunity to make a tornadic attack.
But probably not.


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Hi, I'm a third year student at the University of Exeter and my chosen dissertation topic looks into the future of vehicle technology, how renewable fuels and attitudes shape the current electric vehicle market and how existing electric owners feel and perceive their cars to be representative of themselves.
I have so far been lucky enough to have interviewed a Tesla Roadster owner as a result of a post to this forum. This was most engaging and really very useful for my project.
To achieve a representative data set for my project, I am required to present a number of separate interviews to support my hypothesis. If you feel that you might like to get involved in a project which aims to positively represent electric vehicles and indeed use such a representation to appeal to those 'non-believers' then please get in touch, your participation would be hugely appreciated.
An interview would typically last for no more than an hour and aims to allow you to tell your story in your purchase of an electric vehicle.
For queries or any interest, please send an email to email@example.com
Many Thanks, Lowell
UK, research, electric cars, Tesla