text:
Pope Benedict XVI's announcement Monday that he would resign on Feb. 28 shocked the world, especially its 1 billion Roman Catholics.
Catholics in the American church, 59 million strong, likely had somewhat more mixed reactions to his stepping down than those in developing countries, where his popularity is much higher.
Benedict, 85, succeeded the immensely popular Pope John Paul II in 2005, but is more of an intellectual theologian than a global pastor. That contrast, as well as his continuation of John Paul's policies, may mean his legacy will rest under John Paul's shadow, several people interviewed said.
While Benedict's trip to the United States in 2008 boosted his popularity in this country among the 23 percent who identify themselves as Roman Catholic, their attitudes toward the Holy Father are based more on individual beliefs about moral issues than on Benedict as leader of the church, according to polls and those who have watched him closely.
John Allen, senior correspondent for the National Catholic Reporter, an independent newspaper, said of Benedict's legacy, "I guess the answer is mixed. There is a liberal wing in the Catholic Church who would see Benedict as someone who steered the church in a conservative direction that is not to their taste."
For women, the pope "doesn't have a particularly good record when it comes to their concerns." Benedict famously denounced religious orders of nuns. Conservative Catholics, meanwhile, see Benedict as "the strong leader the times demanded," Allen said.
"I think in general most Catholics admire what they see as the man's humility and grace and I think that came through in reaction to his (U.S.) trip in '08."
While Benedict was at first seen as stern and aloof, the man who said "no" as head of the Congregation for the Doctrine of the Faith, the image of him interacting with Catholic youth made him seem softer and more pastoral, Allen said.
After that trip, 83 percent in a survey said they had "improved impressions, getting past the stereotype of him as a bull in the china shop," Allen said.
Another source of "Catholic pride" is "the perception … that we had a world-class intellectual at the top of the church," he said.
For many, Benedict has been an inspiration. Alex Dahogren, 20, a member of the University Catholic student group at Vanderbilt University in Nashville, said Benedict inspired her when he visited the United States and "when he decided to make this the Year of Faith. Personally, I think it's changed the way we run our organization … Remembering that we are all called to evangelize."
Benedict's image — and possibly his legacy — will be colored by landmark events that preceded his papacy: the reduced role of the Vatican in Americans' view of their faith, starting in the 1960s, and, more recently, the priest sexual-abuse scandals, according to William D'Antonio, professor of sociology at the Catholic University of America in Washington, D.C.
The importance of the "teaching authority claimed by the Vatican" has declined among U.S. Catholics for years, according to surveys D'Antonio has done since 1987.
"The question of the way the laity look at the authority of the Vatican is not one of the four or five items that's at the top of their list," D'Antonio said. Only three in 10 say it's important to them, far less than Jesus' life, death and resurrection, the sacraments, the Virgin Mary or concern for the poor.
This erosion in respect for church authority goes back to Pope Paul VI's encyclical banning artificial birth control in 1968, which overruled two commissions that would have permitted it, D'Antonio said. "It was rejected by a majority of theologians; it was rejected by the laity," he said. From that point, he said, "What happened was the Catholics had an opportunity to think about this in their own lives."
And Benedict, the former Cardinal Joseph Ratzinger, labors in the shadow of the sexual-abuse scandals that came to light before he was elected pope, but which has further eroded church authority.
"So many cardinals and bishops covered up and protected the priests rather than the victims and Ratzinger himself, the evidence shows, did not act," nor did John Paul, said D'Antonio.
In 2010, Gallup reported that Benedict's favorability rating had dropped to 40 percent because of the sexual-abuse scandals, down from 63 percent in 2008, after his U.S. visit.
American Catholicism is diverse, with attitudes and practices differing largely based on age.
More U.S. Catholics see themselves as having greater authority over their own lives than do their church leaders. According to D'Antonio's survey, 20 percent defer to the pope and bishops on divorce and remarriage, 19 percent on abortion, 16 percent on non-marital sex and on homosexuality, and 10 percent on contraception. All of these are considered unalterable teachings of the pope as head of the church.
The most devout Catholics are those born before the Second Vatican Council, which concluded in 1965 and brought major changes to the church, such as ending regular celebration of the Latin Mass. D'Antonio defines "pre-Vatican II Catholics" as those born before 1941.
There are many Catholics who welcomed the changes after Vatican II, but are concerned that John Paul and Benedict tried to bring the church back to the time before the reforms. D'Antonio defines Catholics born between 1941 and 1960 as Vatican II Catholics, who made up almost half of all Catholics in 1987, according to a 2011 article in National Catholic Reporter, which is an excerpt from an upcoming book.
The most recent generation, born after 1979, tend to set their own moral compass and are more interested in the church's concern for the poor and the environment, D'Antonio writes.
Others see the move back to the days of the Latin Mass and more formal liturgy as a positive.
"Much of the good that's happened in the church, restoring the liturgy to some semblance of sacredness — he's had a role in that," said Jack Fowler, of Milford, Conn., publisher of National Review, who attends church daily and says the rosary "several times a day."
Fowler is pleased that "rock 'n roll on the altar" has had its day.
"I think Benedict brought stability and clarity to the liturgy and that's the most important part of our faith … the Mass; it's critical," Fowler said.
The Rev. Joseph Fessio, founder of Ignatius Press in Florida, goes even further. "The heart of the Catholic Church is the worship of God and the liturgy and (Benedict) was one of the greatest liturgists we've had in 100 years," said Fessio, who called Benedict "a giant" with "a brilliant mind" who is "a good listener" and, like John Paul, an admirer of the arts.
Fessio's definition of a true Catholic is unyielding. "You have to accept those things that are taught by the Catholic Church as part of our faith," he said. And there are plenty of those in this country.
"Every day we ship out a stack of books that's as high as the Empire State Building," Fessio said of his publishing house, whose titles include "Modern Moral Problems" and "Contemplative Provocations."
Others take the opposite view. Sister Jeannine Gramick of Maryland, a member of the Sisters of Loretto and board member of the National Coalition of American Nuns, said, "Our evaluation of his legacy is he has turned the clock back in not affording the laity their rightful place in the church, which is to be active participants in the church."
Starting with Pope John Paul and continuing under Benedict, the Vatican has become "more monarchical and less democratic than the Second Vatican Council envisioned it to be," Gramick said.
Benedict also launched investigations of several sisters' orders that play active roles in society, some of which are outspoken in their dissent.
"Our feelings are of hurt, some are very angry and we just feel affronted that we are underappreciated and undervalued," she said.
While there are those who are unhappy with Benedict's eight-year papacy, 74 percent of American Catholics were satisfied with the leadership of their bishop and the pope, according to a 2012 survey by the Pew Forum on Religion and Public Life. Both, however, fell behind sisters and their parish priest, who were favored by 83 percent and 82 percent, respectively.
"By and large, most Catholics are not thinking about what's going on in Rome … but what's going on in their local congregations," said Jon Nilson, professor of theology at Loyola University Chicago.
The American church is evolving, remaining at about 23 percent of the U.S. population, but becoming more heavily Hispanic. This shift may not change attitudes much, however. While 53 percent of American Catholics favor same-sex marriage, 54 percent of Latino Catholics do, according to the Pew Forum.
"The diversity is sort of the key here," Nilson said. "There would be a certain group that would reflexively applaud and honor his legacy simply because he's the pope." Others "fundamentally agree with his priorities and perspectives," such as having "opened the door to return to the use of Latin and some of the older styles of liturgy," while a third group "would be pretty dissatisfied," because of those decisions and what they see as a lack of action on issues such as same-sex relationships, women's roles and the sexual-abuse scandals.
Besides the liturgical reforms, one of the strong messages of Vatican II was greater involvement by the laity. "Many people would say there's got to be more public conversation in the church. There are major issues facing the church that a lot of thoughtful people have given a lot of time to," Nilson said, including the ordination of women, priestly celibacy and same-sex relationships. But the pope refuses to open a dialogue on these issues.
Benedict "may be the last pope whose fundamental education and perspectives were formed prior to the Second Vatican Council," Nilson said.
"I think that for being such a great intellect that he was, he really had a blind spot when it came to issues of homosexuality with all the wealth of discussion around the world," said Francis DeBernardo, executive director of New Ways Ministries in Mount Rainier, Md., which advocates for LGBT rights. "He seemed content to stay with knowledge that was hundreds of years old."
DeBernardo said that as Cardinal Ratzinger and as pope, Benedict "was the architect of some of the worst anti-gay policies that the church has had. … I'm hoping that the next pope will be more open to discussion of LGBT issues and will listen to the lives and reality of LGBT people and their faith."
The most damaging issue Benedict has had to deal with, however, is the sexual-abuse scandal, which he inherited. While he has met with victims, something John Paul never did, Benedict has not done enough to tend to the victims or to sanction the perpetrators, according to several people interviewed.
"My own sense is that the average Catholic knows that the whole thing was terribly mismanaged in 10,000 different ways," said Nilson.
Fowler, the conservative publisher of the National Review, said "I think he has maybe a B if I were giving a grade. The (abuse) problem persists. I hope and pray that … the molestation has stopped."
"I still think they have a bit of a tone deafness to what's transpired … I do think the church should be more aggressive.
"Our church has a long history of being too obtuse to crimes committed by clergy and I feel in the last 10 years things are better but we still have a long, long way to go," Fowler said.
Barbara Blaine of Chicago, president of the Survivors' Network of Those Abused by Priests, said Benedict should have done much more.
"I think that it's very important that we look at the pope's actions and judge him by his accomplishments, not on his words and not what he said," she said. "Because I believe that while he may have made lofty statements, those statements have really not done anything to protect children. And the way to protect children is to take concrete action."
Among those actions are ordering bishops to post identities of sexual predators on their websites, which about 30 bishops have done, to order bishops if they have "any information or documents or evidence that they have about sex crimes that they should turn that over to the police."
It's impossible to know how much the scandal will damage Benedict's legacy over time. Many Catholics place the blame only on the perpetrators, not on their superiors.
Vanderbilt's Alex Dahogren, who thinks Benedict handled the issue well, doesn't blame the Vatican. "The sex-abuse scandals are more on individuals than on the church," she said. "It's not a reflection on the church."
As a new pope is elected, possibly someone from a younger generation, the National Review's Fowler is looking for someone similar to John Paul and Benedict. "We have to be people of hope," he said. "We've had two very good stewards of the faith in very difficult times in a world that's gone hog wild on materialism and without them the state of the church should have been much worse."


text:
SANFORD — You could be eligible to receive as much as $5,891 back from the IRS.
If you earned at least $1 and less than $50,000 from wages, self-employment, or farming in 2012, you may qualify for a refundable tax credit called the Earned Income Tax Credit, or EITC — but you must file a federal income tax return claiming the credit to get it.
Since 2002, York County CA$H — Creating Assets, Savings & Hope — at York County Community Action (YCCAC) has helped almost 2,300 York County residents collect $5.5 million in federal and state tax refunds at FREE IRS-sponsored VITA (Volunteer Income Tax Assistance) sites throughout York County. Nearly $2.7 million of that refund was in EITC alone. In fact, YC CA$H has the distinction of serving one of the highest rates of EITC-eligible filers (65-percent last year) of the hundreds of VITA programs nationwide.
The EITC has been making the lives of workers a little easier for more than 37 years. Yet it remains little known, possibly because people move into and out of eligibility as their financial, marital, and parental statuses change. IRS estimates four of five eligible workers claim their EITC. That means that up to 20 percent are missing out. According to the IRS, rural and non-traditional families, such as grandparents raising grandchildren, childless workers and non-English speaking taxpayers are among those who most frequently overlook the credit.
EITC can be a boost for working people, their families, and communities. Workers who experienced a drop in their earnings in 2012 may qualify for the first time. Even if not required to file a tax return because of low earnings, those who worked even a part time or temp job for just a couple of weeks in 2012 should check to see if they are eligible for EITC.
"We have seen refunds of more than $800 for folks who had as little as $2,000 in earnings," explained Rhoda Butler, the York County CA$H coordinator. "We can also file tax returns covering tax years '09 to '11, so those who have missed out may still collect. Many of our filers have used their substantial refunds to reduce debt, increase savings and even buy a home. It's very exciting to see the impact of this."
"CA$H Coaches" are available to inform filers about smart ways to grow their refunds, with opportunities like split-refund options, matched savings accounts, education and career information, money-management and credit skill-building, resources for business start-up and much more!
To make an appointment for this valuable service that could save hundreds of dollars in tax preparation fees, York County residents can call the CA$H Tax Prep Line at 324-5762, ext. 2718, or call toll-free in Maine at 1-800-965-5762, ext. 2718. The program's eligibility specialist will screen filers for appointments in Sanford or Biddeford.
York County residents may be eligible for free tax preparation at YC CA$H if they qualify for the EITC or participate in any YCCAC income-based programs. Other filers can call 2-1-1 in Maine to locate an AARP Tax-Aide site near them.
YC CA$H is one of eleven members of CA$H Maine, a statewide coalition that provides opportunities for hardworking Mainers from York to Aroostook county to build assets and get ahead. CA$H Maine and its members are sponsored by an IRS VITA Grant, The Annie E. Casey Foundation/Casey Family Services and KeyBank.
York County CA$H is a program of York County Community Action Corporation, whose mission is to alleviate the effects of poverty, attack its underlying causes and to promote the dignity and self sufficiency of the people of York County.

subset: commoncrawl


text:
Search over 1 million properties and 550 airlines worldwide
Free cancellation on most hotels. Because flexibility matters.
Reviewed on Jul 8, 2020
Reviewed on Jul 9, 2020
Reviewed on Jul 7, 2020
Reviewed on Jul 7, 2020
Reviewed on Jun 10, 2020
Reviewed on Jul 7, 2020
Reviewed on Jul 6, 2020
Reviewed on Jul 4, 2020
Reviewed on Jul 2, 2020
Reviewed on Jun 23, 2020
Explore America's Finest City without exceeding your travel budget.
With so much to see and do in San Diego, spend more on cruises around the harbor and less on the price of your hotel.
Don't blow your entire budget on your room, and instead book a 3-star hotel in San Diego to experience comfort without breaking the bank. These three-star accommodations have all the amenities you need, at prices you can afford. You'll find comfortable and spacious guest rooms and amenities such as on-site dining, gyms, and swimming pools. Forget about staying at an over-the-top hotel outside of your budget, and revel in the little perks.
Here at Expedia, we connect you to the best San Diego three-star hotels. Let us help you save money on your hotel, so you can spend the day taking surf lessons in Pacific Beach or kayaking in La Jolla Cove with cash to spare. Check out San Diego airport hotels for easy access to all of the city's major attractions or accommodations within walking distance of the seaside. Customize your vacation with our vast selection of hotels within your price range today.


text:
Provided by: libpod-pseudopod-perl_0.18-2_all
Pod::PseudoPod::DocBook -- format PseudoPod as DocBook
use Pod::PseudoPod::DocBook; my $parser = Pod::PseudoPod::DocBook->new(); ... $parser->parse_file('path/to/file.pod'); Before sending in your manuscript, check that the formatter produced a well-formed DocBook file with xmllint: $ xmllint --noout --valid book.xml
This class is a formatter that takes PseudoPod and renders it as DocBook 4.4. This is a subclass of Pod::PseudoPod and inherits all its methods.
Pod::PseudoPod, Pod::Simple
Copyright (c) 2003-2006 Allison Randal. All rights reserved. This library is free software; you can redistribute it and/or modify it under the same terms as Perl itself. The full text of the license can be found in the LICENSE file included with this module. This library is distributed in the hope that it will be useful, but without any warranty; without even the implied warranty of merchantability or fitness for a particular purpose.
Allison Randal <firstname.lastname@example.com>


text:
Morgification is something I've been thinking about for months. In part, as the involuntary and evil twin of Borgification, and in breadth as a process that derives "morg" from its original word-root as a condition of death. It only so happens that All Hallows Eve is on our doorstep and this haphazard piece turns out to be timely. The inspiration didn't come from philosophy or religion, but from polymer science; specifically, the activities of the (defunct) Polaroid Corporation and the men who were dipping their probes into the mysteries of organic stereochemistry to make "interesting" plastics. And then there's the overall driver which is a psychic hologram of scientific tyranny. Pardon my negativity but there's a problem Houston! We're losing the Race for Space –and I mean losing control of those engineered aliens ( the "race" for space). So, I guess what I want to say is: get jiggy with it science guys or get morgued for a comeback as zombie pumpkins.
"Morg", of course, is taken from Morgellon's, a name on overdrive, standing in for the range of disorders manifesting as recurrent lesions, extruding fibers, films, crystals, technological objects and insects oozing and tearing out of people's skin. Prognosis unknown. Morgellon's suggests these are medical problems. Morgification, I'm suggesting, is conquest.
No one can yet tell me if it's killing people because so far what I've heard is that 'morgs' are killing themselves. I have too little to offer in the face of this tragedy, but recent exposure to advanced cases of morgification support a conviction that the issue needs to be, and must be, defined. It was Edwin ("call me Din") Land, the founder and genius of Polaroid, who was fond of telling people that a problem defined opened the way to its solution.
The following description and accompanying photos (in the link) fits some of the morg specimens I've seen: "In this work, we discovered that.. PVP could self-assemble to form a macroscopic matrix made of a branched hollow polymer nanofibers… The self-assembled fibrous PVP structure formed in the aqueous solution was a jellyfish-like three-dimensional aggregate with a centimeter scale… Based on the..analysis of the early stage during the formation of the jellyfish-like PVP aggregate, the aggregate formation process can be divided into two steps: formation and fusion of PVP microspheres into pearl-necklace-like chains and growth of hollow fibers from the chains… The branched fibers produced in this work may serve as new templates for the synthesis of fibers or tubes of other materials… We discovered that polyvinylpyrrolidone (PVP) could self-assemble into branched hollow fibers in an aqueous solution after aging the PVP solution for about two weeks. Based on this finding, we demonstrated two approaches by which the self-assembly of PVP into branched hollow fibers could be exploited to template the formation of branched hollow inorganic fibers." [i.e. silica and gold nanoparticles] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844465/
PVP powder, sold widely as a food additive, binding and thickening agent for foods, adhesives, pharmaceuticals, cosmetics, medical devices and blood plasma substitute. Mixed with iodine it's called povidone, able to make light-polarizing film — it could have been among the many thousands of polymer compounds prepared by Polaroid.
Edwin Land, c1947
For much of its early existence, Polaroid functioned as a think tank more than a product-wielding corporation. In 1937, Polaroid was officially reorganized "Under the enthusiastic sponsorship of Jimmy [James A.] Warburg, [as] a group came together that included W. Averell Harriman, Lewis Strauss and Strauss's partners at Kuhn Loeb, and several members of Schroder-Rockefeller… and clearly demonstrated what they were investing in by granting Land control of a voting trust of the stock… The board directors [were] Warburg, Harriman, Strauss…" [p55, Land's Polaroid] Din Land had shown them miracles, including a 3-D movie, which they restaged multiple times for scientists, capitalists, and the press. For the 1939 "World of Tomorrow" Fair in New York, Chrysler presented a 3-D Polaroid film of a car self-assembling as the animated parts danced before the audience. Still, Polaroid had little to sell and fewer customers, but 1940, World War II, new premises near M.I.T. and a flow of contracts from the US Navy changed everything. Near the end of the war, Polaroid took on a team of crack chemists and set out to make the products that Edwin Land had dreamed of.
One of the chemists who signed on to Polaroid in 1943 was Elkan Rogers Blout, newly promoted out of Columbia University with a chemical PhD and accommodated as a research fellow at Harvard Medical School. Blout managed to keep his parallel life going between Polaroid and Harvard –Polaroid gave him wealth and Harvard gave him prestige– until 1962 and the fruition of Polaroid's great commercial one-trick-pony: the instant color camera. Blout "led the team of chemists that synthesized more than 5,000 compounds in search of the key ingredients of the Polaroid color process." http://www.hsph.harvard.edu/news/press-releases/2006-releases/press12202006.html By leaving the lab at Polaroid, Blout was to have time to make his mark in medicine. Since 1950, he'd had private lab space at the Children's Hospital in Boston, sponsored by the Children's Cancer Research Foundation under Sidney Farber: "Elkan established a spectroscopy laboratory at Children's..to study biophysics of peptides and proteins… Indicative of his stature in the field of biopolymers, Elkan was a founding editor of the journal Biopolymers…" http://news.harvard.edu/gazette/story/2007/09/elkan-r-blout/ At the top of his Harvard career, Elkan Blout was the Dean of academics at the Harvard School of Public Health, treasurer of the National Academy of Sciences responsible for a five-fold increase in monetary holdings and lastly, in retirement after having won the highest national awards, senior science advisor to the FDA. But, from his first days at Polaroid during WWII, Blout (who was 24 at the time) had joined in the 'classified' culture of military secrets. It may have taught him much about networking and discretion, as doubtlessly as hobnobbing with financiers did with money. Perhaps it suited him as it suited Edwin Land.
When the Korean War kicked into gear and nuclear tests moved to Nevada, Edwin Land joined another small group to study and recommend military development; they called themselves the Beacon Hill group and issued a highly classified report on ideas for aerial reconnaissance and atmospheric monitoring. Land's fellow in these studies, James R. Killian (pres. of M.I.T), was later to pick him as chair for the special intelligence committee. In 1954, Land and Killian, together, went to Eisenhower with the plan for the U-2 spy plane. It was at Land's urging and arrangement that Kelly Johnson of Lockheed was brought into the project, and potentially many other contributors as well. "He knew much of the country's scientific establishment personally. He was a visiting lecturer at M.I.T. and would later persuade Killian to join Polaroid's board… Land quickly assumed a leading role… From the first flight on July 4, 1956, to the day Gary Powers was shot down on May 1, 1960, the U-2 changed the course of history… suddenly a hidden world was totally revealed. It quickly became apparent that the bomber gap and the missile gap [promoted as falling behind the Soviets] were misapprehensions… the Western powers had overestimated Soviet strength… Subsequent flights totally revised American and NATO thinking about Russian capabilities." [pp111-112, Land's Polaroid]
The essential telling of U-2 surveillance and the involvement of Land is in the timing of its early flights a full year before the United States blew off the longest and dirtiest series of nuclear bombs over the heads of its citizens. The Nevada tests known as Operation Plumbob in the summer and fall of 1957 initiated the period of peak atmospheric fallout that, according to epidemiological data, has never really abated due to the growth of nuclear industries, accidents, re-pollution and bioaccumulation. For some time now, even the public knows that the 'testing' excess was militarily unnecessary by any standard. In the field of synthetic and biopolymers, however, fallout is magic.
Got a minute?
"In 1927, prior to the Wall Street Crash and the construction of Rockefeller Center, Standard Oil and I.G. Farben formalized a joint partnnership that created the world's largest chemical consortium. Howard Ambruster published a critical work in 1947 on the interwar history of the Standard-Farben venture: "Treason's Peace, German Dyes and American Dupes". Ambruster wrote, "..it is and must be recognized as a cabalistic organization which..operates a far-flung and highly efficient espionnage machine –the ultimate purpose being world conquest and a world super-state directed by Farben." www.archive.org/stream/treasonspeaceger00ambrrich/…" http://polioforever.wordpress.com/the-rockefeller-institute/
"Under the direction of Walter Reppe (1892 – 1969, chemist and member of the Board of Executive Directors from 1952 to 1957), research begins in 1928 on the catalytic reactions of acetylene under pressure… Carl Bosch and Friedrich Bergius receive the Nobel Prize for the development of high-pressure technology for ammonia synthesis and coal hydrogenation…Researchers in Ludwigshafen develop a groundbreaking new invention – magnetic tape… Ten years of intensive research into synthetic rubber culminate in success… A patent is filed in 1939 for one of the most interesting derivatves of acetylene chemistry: polyvinylpyrrolidone (PVP)… Times of war, 1940…The first 20 tons of caprolactam-based polyamide are produced in Ludwigshafen. This opens up new ways of manufacturing fibers (nylon and Perlon) and engineering plastics… " http://www.basf.com/group/corporate/en/about-basf/history/1925-1944/index
"I.G. Farben had a holding company in the United States… Paul M. Warburg, first director of the Federal Reserve Bank of New York and chairman of the Bank of Manhattan, was a Farben director and in Germany his brother Max Warburg was also a director of I.G, Farben. H. A. Metz of I.G. Farben was also a director of the Warburg's Bank of Manhattan. Finally, Carl Bosch of American I.G. Farben was also a director of Ford Motor Company A-G in Germany… Another elusive case of reported financing to Hitler is that of Fritz Thyssen, the German steel magnate…[whose]..personal banking operation was affiliated with W.A. Harriman interests in New York.." http://reformed-theology.org/html/books/wall_street/chapter_07.htm "Virtually all members of the German Warburg family fled to the United States or Great Britain by 1938." http://en.wikipedia.org/wiki/Warburg_family "The I.G.Farben cartel was created by loans from Wall Street in what has been called the Dawes Plan. Carroll Quigley calls the Dawes Plan 'largely a J.P. Morgan production.' The J.P. Morgan Group set up the loan to I.G. Farben, which created Hitler… Do you see what happened? A Rothschild agent [Morgan & Co.] set up a cartel that was directly involved in the horrible persecution of the Jews. Still the family maintains the illusion of being totally supportive of their race. At first Germany had a significant disadvantage… The nation had a fuel shortage…[but] were able to fight WWII through the use of synthetic fuels that were created by the hydrogenation process (turning coal into gasoline)… Standard Oil..was able to complete the research, facilitating the war…" [from Bloodlines of the Illuminati, by Fritz Springmeier, http://www.whale.to/b/sp/rothschild.html]
"While the processes for producing gaseous and liquid fuels by conventional techniques were being developed, exploratory experiments to investigate the rapid pyrolysis of coal to gaseous products were in progress… The results of these studies show that the rapid pyrolysis of coal produces a gaseous mixture of which acetylene is the principal hydrocarbon constituent…" http://web.anl.gov/PCS/acsfuel/preprint%20archive/Files/13_4_NEW%20YORK_09-69_0321.pdf
The US Government's sample of PVP came to the military in 1943 as captured German medical supplies: "At the 28 July 1943 [Subcommittee on Blood Substitutes] Conference..a bottle of Periston [polyvinylpyrrolidone]..that had been captured in Tunisia..was exhibited and arrangements were made for various studies to be conducted on it… [T]oxicity experiments revealed gross pathologic changes in the spleen..described as the type to be expected in severe bone marrow damage… Autopsy also revealed changes in the liver that were apparently progressive…" http://history.amedd.army.mil/booksdocs/wwii/blood/chapter14.htm Despite this, blood substitute science was unable to find suitable materials and Periston was bypassed because of adequate supplies of donated blood from the Red Cross program. The military dropped its inquiry at the end of the war, but in 1950 the Korean War revived their interest: "Periston was..[next] considered in the Subcommittee on Shock on 14 October 1950. Although it had been widely used in Germany during WWII and about half a million cases had since been followed up, not much was known… Apparently it caused no lasting damage to the tissues… At the 11 December..meeting..it was learned that the Schenley [Distillers] Corp. could then import 5,000 to 10,000 bottles of Periston a month from Germany and by July 1951 expected to import an intermediate form that could be processed further in the United States… A research project had been approved in principle… The Food and Drug Administration was prepared to clear Periston…" http://history.amedd.army.mil/booksdocs/wwii/blood/chapter20.htm [pp788-790] So Schenley Corp. became the government's PVP contractor until late 1953 when Periston was dropped again in favor of another blood substitute called dextran –also provided by Schenley.
"Schenley had been owned by one Danny Weiskopf, formerly the right-hand man of Julius Kessler, the whiskey king of pre-Prohibition America. Weiskopf had sold out to Lew Rosenstiel..[who] managed to build up considerable stocks of 'prescription whiskey'..[p95, The Bronfmans]… Before Repeal Rosenstiel had acquired..the important firm of Schenley with the help of..the totally respectable banking firm of Lehman Brothers… Rosenstiel was a true monster… He was a workaholic, needing only two hours of sleep, working seven days a week, impetuous.. a control freak who treated his employees like dirt, sacking them at a moment's notice..[expecting] them to compromise themselves by talking in his absence, unaware that he had installed bugging devices in his offices… Rosenstiel was married four times and was bisexual…revealed from evidence given in a bitter divorce suit..by his fourth wife. If, as is possible, her evidence is true, it guarantees him a place in history as organizer of the parties at which J. Edgar Hoover could frolic in his favorite frocks, parties that featured boy prostitutes for the enjoyment of..guests like Roy Cohn. According to the fourth Mrs. Rosenstiel, at one party she attended Hoover 'was wearing a fluffy black dress..with..lace stockings and high heels..makeup..and false eyelashes.' Indeed it was the blackmail potential of the conversations recorded on the microphones Rosenstiel had thoughtfully installed throughout the house that allegedly explained Hoover's refusal to pursue the Mafia. For it was at Lew's place that Hoover met some of Rosenstiel's business associates..like Frank Costello, Sam Giancana…Santo Trafficante..Angelo Bruno..and Meyer Lansky…" [p66, The Bronfmans, by Nicholas Faith] Sam Bronfman bought a 20% stake in Schenley. "Mr. Sam..–and above all Edgar– had been introduced to what would now be called 'insider' stock market dealings by the Loebs and the Gunzbergs… In France the Gunzberg connection with the Rothschilds enabled the Bronfmans to get in on the ground floor of..the innovative holiday group Club Mediterranee. In the United States the investments included a highly successful speculation into Polaroid.." [p175, ibid.]
This story, as you might surmise, has more places to go than tunneling nanotubes, and at some point I just have to leave-off and mention that the early medical research on PVP by the government was mixed at best. They sanctioned 'emergency use' of PVP blood substitute and called for more study. The only moderately favorable clinical trial done in 1950 was submitted by Dr. Robert M. Zollinger of Ohio State U, the beloved mentor of Judah Folkman who got him into Harvard Medial School. Polaroid eventually filed a number of PVP-containing patents, some of which appear near the end of Edwin Land's life in 1983. "Paradoxically, a man who spent much of his life developing devices and systems for recording history didn't leave much of his own. He didn't keep a journal and his personal papers were destroyed upon death." http://www.2think.org/land.shtml


text:
The best session of the Lightreading Ethernet Conference covered Wireless Base Station Backhaul. Patrick Donegan of Heavyreading and the panelists presented cohesive data and their take on which way the market would head. I gained a new perspective on the opportunity wireless backhaul presents.
The fundamental problem wireless carriers face is the underlying shift from voice dominated to data dominated traffic. Voice is growing linearly, while data is likely to grow exponentially. If leased copper T1's are used for backhaul, their backhaul costs will scale linearly as capacity is added.


text:
How much does Thankgiving dinner cost?
The cost for Thanksgiving dinner in the U.S. will fall to the lowest in three years as consumers pay less for turkey, stuffing and rolls, according to the American Farm Bureau Federation.
The average expense of feeding 10 people the 12 items typically served for the holiday feast will be $49.04 this year, down 0.9 percent from 2012, the Washington-based group said today in a statement, after conducting its 28th annual informal survey of supermarkets. The cost of the meal has been around $49 since 2011, federation data show. The U.S. celebrates Thanksgiving this year on Nov. 28.
Related: More Americans than ever started holiday shopping early
Most agricultural commodity prices have dropped this year after farmers boosted output, sending corn and wheat into bear markets. Global food costs tracked by the United Nations are 14 percent below the record set in February 2011. In 2012, U.S. livestock producers and grain growers faced the most-severe drought since the 1930s.
"The cost of this year's meal, at less than $5 per serving, remains an excellent value for consumers," Bob Stallman, the federation's president and a rice and cattle producer from Texas, said in the statement.
Turkey prices fell 2.1 percent, or 47 cents, the biggest single decline, according to the survey. The national average price for a 16-pound bird is $21.76, or $1.36 a pound, according to the federation. That doesn't include store promotions or rebates.
U.S. warehouses held about 325.6 million pounds of frozen whole turkeys at the end of September, up 6.6 percent from a year earlier, the latest government data show.
RELATED: What are busiest days for holiday shopping?
"Most Americans will pay about the same as last year at the grocery store for a turkey and all the trimmings," John Anderson, the federation's deputy chief economist, said in the statement. "Slightly higher turkey production for much of the year, coupled with an increase in birds in cold storage, may be responsible for the moderate price decrease our shoppers reported."
The cost of 12 rolls fell 15 cents, the biggest decline after the turkey, to $2.18. Prices for green peas, fresh cranberries, and pie shells fell.
The cost of 3 pounds of sweet potatoes rose 21 cents, the biggest gain. Prices also increased for pumpkin-pie mix, whole milk, relish made of celery and carrots, and whipping cream. Items including onions, eggs, sugar, flour and butter to prepare the dinner rose 2 cents.
The federation's survey was first conducted in 1986, and the menu for the dinner has been unchanged since then to allow for consistent price comparisons. A total of 167 volunteer shoppers checked prices at stores in 34 states.
Get U-T Business in your inbox on Mondays
Get ready for your week with the week's top business stories from San Diego and California, in your inbox Monday mornings.
You may occasionally receive promotional content from the San Diego Union-Tribune.


text:
Luxury Quartz Wooden Square Watch
Collections: ACCESSORIES
Collections: ACCESSORIES
Shipping method: Standard Shipping. Tracking and secure check out are provided for all orders.
Processing Time: 3 – 5 days* in regular seasons.
Shipping Time: 8 – 20 days* in regular seasons.
(*) might be delayed 2 - 4 days due to the peak season, but we will try our best to fulfill orders as fast as we can. Average transit times are typically received in 3 weeks.


text:
ScreenTech talks to Steven Poster about the cinematographer's place in a new digital landscape.
Steven Poster, ASC is president of the International Cinematographer's Guild (ICG), Local 600 and has shot a wide variety of film and tv, including Donnie Darko, Roswell and Someone To Watch Over Me. He also serves on the Academy of Motion Picture Arts and Sciences Nicholl Fellowships Committee and on the board of Craft in America. He has also been President of the American Society of Cinematographers.
ScreenTech: Has the shift from film to fully digital production made the cinematographer's job more challenging? Has it been difficult to adjust to?
Steven Poster: In a lot of respects, the cinematographer's job hasn't changed at all. First of all, I am not nostalgic for film personally – yes, I do miss my Kodachrome - but a lot of people are. Everybody I know has made the digital transition handily without a problem. But of course, there is a lot of nostalgia for film. Film is a very elegant solution to doing this work. And the idea that it's become easier or cheaper or faster is a complete falsehood. That's something that people on all sides are realising at this point.
It is a more complex system. But it does give us a certain amount of flexibility that didn't exist before. I think there are great advantages and that there is little downside, other than the loss of that romance of film, which was lovely. It was a lovely, simple, relatively easy solution for anybody who had the craft and had the art. We've been doing it for 100 years: you put the film in the camera, you push the button, you take the film out of the camera and you go home.
ST: And no one was trying to get you to upgrade to a new type of film every year.
SP: The image control that we had was the choice of lenses, the choice of film, the choice of filtration and the laboratory techniques. Those four elements could create millions of different looks. The control we had was that we understood the process very thoroughly. It was in our veins, you know. Now, each camera is equivalent to a new emulsion. Filters are still filters and still do the same work, and in fact are more important today than they ever were. Lenses are still a major choice in how we record the images. And the equivalent to laboratory technique is the way we grade the material.
The difference between grading now and in the old days is that grading used to happen in the laboratory, now it's on set. I had an experience just this summer where I was shooting a TV pilot with the Canon C300. Tiffen had made me a combination filter that was quite elegant, with a combination Pro-Mist and Glimmerglass. It had a lovely, glowy, pearlescent look. And I also had a full DaVinci Resolve system on the set, where I would go and colour the master after the first take, or in between the first and second takes, or even in the rehearsal take with the stand-ins, and create the look of that scene. It took no time at all, it was very fast. And the magic did not disappear. The magic was still there. People would come over and see what we were doing and they would get this sense of magic immediately, as opposed to having to wait for dailies from the lab. It was a very exciting way to work.
The Canon cameras were brilliant. One of the great advantages we have now with these cameras is that we can shoot at a much higher exposure index, so there's much more sensitivity with a lot less noise. Except for day exteriors, I was shooting at 3200 ISO, and that gave me a whole new life in lighting. So am I sad that we don't have film any more? To have that onset control of the look that will flow all the way through to the final was very exciting.
ST: How have digital workflows been a challenge to how the set operates?
SP: In America, a number of years ago when digital projection was starting up, a consortium the studios and other organisations put together a group to study what was the best way to deliver motion pictures to theatres and project and create standards and practices. It was called Digital Cinema Initiative. Everybody got together and worked on it and did the best work they could for the industry. Now I'm calling for another consortium to work together to develop processes for getting the files from the set into the editing room and colouring and protecting and cloning.
We don't want to change anyone's workflow. There are millions of workflows and everyone has their own preference. In fact, my friend Leon Silverman, Disney's VP in charge of digital strategy, says "workflows are like snowflakes - no two are alike and the moment they hit the ground, they disappear". But we need to come together as an industry to determine what minimally are the best practices to ensure that the material is going to be handled safely and properly and that we prevent catastrophic data loss and get the material from the set into the editing room properly. And there are a number of studios that are interested in coming together and doing it.
The new digital workflows and changes onset have been a major transition. I feel for these post production companies that are scrambling to find a way to stay alive. Technology developers – the engineers, the scientists, the companies that manufacture – have developed cameras and systems so rapidly that these traditional laboratories and post production facilities almost have nowhere to go to keep their business.
We were at a Hollywood Post Alliance luncheon and the head of the Hollywood Post Alliance said "look around you, next year 40% of the businesses in this room will have disappeared". It's frightening. And that's not for any other reason than that there have been technologies that are developed that have taken over that work and is all now done on the set. So the companies are scrambling to find a way to keep a piece of that business and it's hard. There has been a lot of trying to define what the crew looks like, and who does what where, and the Cinematographer's Guild has been working with this very carefully for a long time.
ST: What has the Guild done to help cinematographers adapt to changing technology?
SP: One of the most important things the Guild has done is training. In fact, the minute file-based recording came around we developed a training programme for our loaders. And we developed our own best safety practices. We trained over 700 people across the country to do this kind of work, all with the intent of training people how to prevent catastrophic data loss. In the early days, producers would try to get some kid out of college with a Mac and they would end up being the ones handling the most important material of the show, and there were so many instances of lost or damaged material, that it became almost a joke. So we developed, and we trained, and we came up with the methodology of handling this digital material early on and it gave our members a leg up in terms of what the industry really needed. I'm very proud of that.
ST: What is the biggest challenge that the industry is facing now? Is it the economy?
SP: Well, of course it's the economy. I think it's a wonderful time for cinematography. I think the choices we have now in terms of technology and processes are just making our jobs that much more exciting. And we're living in a time where there is a voracious appetite for media, so there is a tremendous amount of work out there. It's just not the same work as it was in the old studio system. And that's something that people have to adapt to.
I think we're seeing this new worldwide market afford all the young people coming into this business – and there's a lot of them – the opportunity to find ways of making a living. Maybe the high-end, wonderful, tent pole experience with huge crews and great facilities are fewer and farther between, but if you're willing to work within the constraints of lower budgets, there are some wonderful scripts and stories to be told. I think we're in a very exciting time.


text:
Honestly, it boils down to this: Not Rick Wagoner, Bill Ford, Carlos Ghosn, Bernd Pieschetsrieder, J rgen Schrempp, Sergio Marchionne, Roger Smith, Katsuaki Watanabe, nor even Dieter Zetsche nor Lido will ever be known as "Il Commendatore." And this friends, is why modern culture is sucking right now. We need us some Duces, some F hrers, some Emperors; some His Majesties the Whatevers. And then we need a bunch of anarcho-syndicalists just for fun. Throw in a Papa Hemingway for good measure. Remember back in the Eighties when Goodyear used to run the spot that asked something like, "Why does every new Ferrari ride on Goodyear tires?"
(Cut to red italian supercar stopping after haviing blasted up a mountain road, silver-haired, be-sunglassed European man exiting driver's door.) "Because Mister Ferrari wants it that way." Now try imagining Ghosn, for example, leaving the exact same car in the exact same shot. Ghosn's pen probably isn't stocked with purple ink, either. Face it, you'd go buy a set of Sumitomos or Bridgestones just to not be associated with the guy. We're tired of stock-exchange democracy, ridiculous cost-cutting, needless gadgets and lawsuit diplomacy. Adventures with multiple fists! Onward! Upward! Kill the Corolla! Down with the 612 Sca(nk)g! Viva the Corvair Monza! Viva Cannon Ball Baker! Viva chest hair!
A Bit About Wealth Car-Guy Culture [Internal]


text:
Hey, I really want to get a print of this one in poster-size for my cubicle wall:
Do you guys have a print shop set up?
Alternatively, would you guys give me permission to print one for myself in exchange for an Amazon gift certificate or something? (I'm not a big fan of Paypal)
Thanks, and keep up the great work


text:
Summary and Keywords
Perhaps no other American leader has experienced so precipitous a fall from grace as Andrew Johnson, seventeenth president of the United States (1865–1869). During the Civil War, Johnson was the preeminent symbol of Southern Unionism—and thus, the ideal running mate for Abraham Lincoln in the 1864 election, on the Union Party ticket. Four years later, as president, he was widely viewed as a traitor to his political allies and even to the Union, and barely escaped impeachment. In modern scholarship, the image persists of Johnson as politically inept, and willfully self-destructive—driven by visceral emotions, particularly by implacable racism, and lacking in Lincoln's skill for reading and molding public opinion. But such an image fails to capture fully the scope of his political influence. As President, Johnson staked claims that shaped the course of Reconstruction—that emancipation signified nothing but freedom; that the immediate aftermath of the Civil War was a golden moment of reconciliation, which Radicals squandered by pushing for black suffrage; that the Congressional program of Reconstruction inaugurated a period of so-called "black rule," during which former Confederates were victimized and disfranchised. Such propaganda was designed to deem the Republican experiment in black citizenship a failure before it even began. Johnson's term offers an example as striking as any in U.S. history of the power of presidents to set the terms of political debates—and of the power of their words to do lasting harm.
Keywords: Abraham Lincoln, Andrew Johnson, black rule, Civil War, Confederate, impeachment, Reconstruction, slavery, Southern Unionism, Union Party, Ten Percent Plan, Tenure of Office Act
Access to the complete content on Oxford Research Encyclopedia of American History requires a subscription or purchase. Public users are able to search the site and view the abstracts and keywords for each book and chapter without a subscription. If you are a student or academic complete our librarian recommendation form to recommend the Oxford Research Encyclopedias to your librarians for an institutional free trial.
Please subscribe or login to access full text content.
If you have purchased a print title that contains an access token, please see the token for information about how to register your code.
For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.


text:
Ok so in the past day ive seen 2 top 5 threads up here. So i thought, why not make this one? Its bound to ge a lot of people talking, considering we talk about music alot. So what are your five favorite albums ever, the albums that shaped you?
Of course...
Nothing need be said.
Mos Def- Black On Both Sides. This album is really amazing. hiphop at its finest. The song Brooklyn is pure amazing. Plus you got the relaxing beats in it too (Umi Says)
Love it. 6th Sense is pure Common Sense. I think the best song here is the light. The Light is such an amazing song, and tells a beautiful story. Something 99.9% if rappers nowadays cant do...
avenger sevenfold- city of evil
Yes, i like rock too. I love every song on this album, the guitar solos (M.I.A) (Bat Country) are truly beast. My fav rock album. Recommend it for any rock lover.
Yep. My #5 choice is Nas' underrated 2nd album, It was Written. I dont know why so many people considered this a dissapointment, just because of its predecessor. Sweet beats, nice flow, from the man himself, the illmatic ni**a, Nasty Nas.


text: Advances In 3-D May Mean No Ridiculous Glasses April 1, 2011 Movies, TV shows, video games — it seems 3-D technology is everywhere these days. It's creating a competitive market for companies trying to improve the way we experience the illusion of depth perception. Dr. Marsh and his team hope for a wider release of the procedure in select cities starting April 1, 2012. Advances In 3-D May Mean No Ridiculous Glasses Listen · 1:42 1:42 Toggle more options Download Embed Embed <iframe src="https://www.npr.org/player/embed/135033545/135033536" width="100%" height="290" frameborder="0" scrolling="no" title="NPR embedded audio player"> Transcript


text:
My body – my post-partum, baby-slinging, breast-feeding body – defies metaphor. I look at it and figurative language escapes me. I look at it and I don't want to find just the right words, I don't want to put it into poetry (oh body of mother/life-giving belly/breasts that nourish/what-the-fuck-ever). I look at it and I think, ugh.
I know that I am being hard on myself. I just gave birth seven weeks ago. I'm in my thirties. I can't expect my body to just bounce back. And in any case, bounce back to what? To my pillowy, matronly post-Wonderbaby badonkadonked self. To heavy thighs and pouchy belly. To a body that bore all of the signs of childbirth and cinnamon rolls, and none of the signs of grapefruit and granola and exercise. To the body of a mom who looked in the mirror at some point in her child's babyhood and was all, like, whatever.
I didn't care, for a time. I enjoyed not caring. I enjoyed having finally arrived at a point in my feminine psycho-social development at which I did not care, to any significant degree, what I looked like. It's not that I gave up or let myself go or became slovenly (excepting the early days of new, first-time motherhood, which were an exercise in extreme physical disrepair and unparalleled slovenliness) – it's just that my appearance ceased to be a priority. I had never had an intimate relationship with my perfect, youthful body – I wrote (in an essay for future publication) this past fall – I hadn't needed to. So I didn't really know it. But this body, this stretch-marked, lumpy, heavy-breasted imperfect body – this body I got to know. And love. I came to love my imperfect body. And in loving it, I stopped caring about the imperfections. I embraced the imperfections. Somehow – I wrote – unexpectedly, my big, battered maternal body became beautiful – erotically beautiful – to me in a way that my perfect youthful beauty never could, because of its perfection.
I came to love that body, to not care about its imperfections because the imperfections became beautiful to me. I have, now, fallen out of love. The scales, as they say, have fallen from my eyes and when I look down at myself in the middle of a nursing session or while tending to aching breasts or just standing, stock-still from exhaustion, in the shower (having avoided all mirrors, because, oh my god, are you kidding?) I just see pasty, lumpy flesh. I don't see a miracle of nature, I don't see physical accomplishment, I don't see the hard-won padding of a mother in her (rolling brogue here) prime. I see a body defeated, beaten.
Why? Why have the imperfections ceased to be beautiful? Why do I look down at the vast expanse of soft belly and pendulous boob and cringe?
You should be proud of that body, says my husband. It's done amazing things. And: I love to see you like this.
But still I cringe. And I struggle to find words, to reclaim the poetic embrace of my physical self, the embrace can came so easily before this last pregnancy. I struggle to know this physical self and to feel comfortable claiming it as my own. I long to regain the comfort with my self that I had not so very long ago. I long to not gaze at myself so critically. I long to gaze at myself and summon words like snowy and soft and strong and battle-worn-but-beautiful.
I long to see what my mind's eye knows is there: a beautiful new mother. I long to see this, and hope with all hope that I will see it again. But I just can't right now. And that's hard.


text:
Date(s) - 15/11/2019
All Day
Learning about graphic design concepts and approaches of the past can help inform and inspire your work in the present. This is the premise of Foundations of Graphic Design History, a series aimed at designers, artists, and anyone else who wants to understand the history of design. In this installment, Sean Adams focuses on Arts and Crafts, a movement defined by a reaction against the industrial age and Victorian excess, and a renewed focus on the handmade.
Sean reviews the factors leading to the rise of Arts and Crafts, and the designers and companies who led the charge, including William Morris, Gustav Stickley, and Frank Lloyd Wright. Since Arts and Crafts spanned more than print, Sean reviews its impact on architecture, textile and furniture design, ceramics and glasswork, and bookmaking. He also explains what led to the decline of the Arts and Crafts movement , and how its influence on contemporary design lives on.
Sean Adams
Chair, Undergraduate and Graduate Graphic Design at ArtCenter College of Design at ArtCenter College of Design
Founder of design firm AdamsMorioka, Sean Adams teaches at Art Center and designs for clients such as Adobe.


text:
Retirement Home Or Research Lab? Report Weighs Fate Of U.S. Chimpanzees
This morning the Institute of Medicine (IOM) of the National Academies issued a report that opens the door for chimpanzees' continued use in certain biomedical research projects. (Our friends over at Shots also report on this today.) Though the report says that "most current biomedical research use of chimpanzees is not necessary," it sees "notable exceptions" in specific areas.
That the IOM does not endorse an outright ban on pain-causing research using these apes is a disappointment, especially considering the report acknowledges chimpanzees are highly intelligent primates capable of feeling grief and depression.
The IOM says certain forms of monoclonal-antibody and, perhaps, hepatitis-C research (though on the latter the committee split its vote) may require chimpanzees in order to be successful. Further, the report states that it "would not close the door on the possibility that chimpanzees may be needed in future research" concerning diseases or disorders not yet identified.
As I read the IOM report (made available one day early to the media), I felt distress for the 937 chimpanzees currently available for biomedical testing in U.S. facilities. The door that the IOM leaves open may well lead right to pain and distress for some of these chimpanzees.
As the editors of the magazine Scientific American noted when they supported a total ban two months ago, the United States is the only nation besides Gabon that allows its chimpanzees to be used in this way.
I suspect that some people will embrace the report as a step forward on behalf of chimpanzees. Some of the language is welcome, as when the report acknowledges the "moral cost" of using chimpanzees in invasive research. Still, in key passages, the report is weak.
Congressional inquiry led to the IOM's collaboration with the National Research Council in producing this report for the National Institutes of Health (NIH), which funds the majority of federally sponsored biomedical projects using chimpanzees. The IOM report will help determine the fate of 176 chimpanzees currently in New Mexico, whom the NIH hoped to move back to a biomedical arena in Texas. Chimpanzee advocates believe these apes deserve to retire.
Aware that the quality of these chimpanzees' lives hang in the balance, I was powerfully struck by the differences between two sets of guidelines published in the IOM report: those for comparative genomics and behavioral research, on the one hand, and those for biomedical research on the other.
When it comes to genomics and behavioral research, the chimpanzees are, to a degree, in control. The apes must, the report says, be able to choose whether to participate in any given experiment. In the report's language, the chimpanzees must be "acquiescent." In addition, the research must be performed "using techniques that are minimally invasive, and in a manner that minimizes pain and distress."
These two criteria — voluntary participation in combination with minimal pain and distress — are absent from the guidelines for biomedical research. The focus in the biomedical guidelines is on ensuring chimpanzees are the only viable testing method for a line of research critical to human health.
Why would the biomedical guidelines differ? Why do they not speak to the issues of chimpanzee acquiescence or pain and distress? The answer is all too clear: biomedical research would grind to a halt, because no chimpanzees would elect to endure the multiple needles, surgeries, or other invasive procedures involved. The apes would refuse to be "acquiescent" in their own pain and distress.
In the wake of the IOM's report, it comes as an emotional relief to think of apes like Bobby and the others who now live free of laboratory confinement, rescued by the Save the Chimps sanctuary in Florida. Through the outcome for apes like these, we may construct a different door than the IOM's and walk through it. On a reasonable schedule — see the Scientific American editorial on this point — chimpanzees currently available for biomedical research should be retired. Let these magnificent creatures reside where they may be "acquiescent" in their own peaceful lives, free of pain and distress.
You can connect with Barbara on Twitter.


text:
(Please follow me at @MayerSpivack on Twitter for further articles and discussion)
Perhaps I am overreacting to a query at the end of an article discussing the implications of Quantum entanglement in organic environments—Technology Review by K. Birgitta Whaley et al. at the Berkeley Center for Quantum Information and Computation as published in Quantum Physics — but writing from the bottom of my limbic system, here goes —.
If there ever was an organ that might benefit from quantum entanglement it is the brain. If there is a system in the brain that would benefit most from entanglement it will involve associative process. Consider:
Quantum entanglement for information storage at the origin and terminus of nerve fibers in the brain might allow instantaneous signal processing at multiple locations within the brain that have in the past become associatively categorized and connected. This would make the brain operate as a far more energy-efficient organ. It could run cooler, require less sugar-fuel, and have a faster response-time and be free of the time-lag that is a product of transmission speed as a function of nerve fiber length. Cells located a few inches apart could be called upon to fire instantaneously (speed of light? no measurable speed?) and perhaps also to act simultaneously (seizure? migraine? consciousness?).
Pushing the envelope of the possible, credible and the probable:
Were it possible that entangled particles could be found at both ends of nerves, and that this entanglement could be produced not only in entangled pairs, but among great entangled families or multiples (think of: neural web), in other words—that they could be replicated, and their tangled-together potential to interconnect could be maintained over time by some yet unknown and unobserved mechanisms—then—quantum entanglement might yield advantages in associative processing power and speed within the brain.
Assume that associative memory and recall processing, (including processes of attention direction, memory formation, and memory recall) involves a great number of cerebral cortex end-point locations that are discrete and separate cells. The origins (in space, time, and entanglement) of these connections would lie somewhere among sensory systems and within the limbic lumps.
For associative connections to be made among many such end-points, transmission and process speed would benefit from (and perhaps require) multiple simultaneous real-time connections among a plurality of distal end-points that were first entangled when sensory, attention or thought stimuli first originated at a sensory organ or from within somewhere in the limbic system, or within the cerebral cortex itself (as in the case of thought and imagination).
Linear/logical processes (think of: tax accounting) would not require such massive investment in cellular connections or wiring as would associative / syncretic processing (think of: scientific hypothesis-making, art, invention).
Hypothesis: most untrained (unschooled), or 'native', 'spontaneous' thought process is associative, not linear.
A corollary hypothesis: education deals with almost exclusively with teaching and training in linear / logical processing at the expense of associative / syncretic processing.
This emphasis on logic eventually suppresses associative / syncretic processing, causing associative neural connections to devolve or disappear.
If quantum entanglement among a myriad of endpoint memory cells and attention systems or cortical cells were possible, then it might allow the communication structure of the brain to bypass the expensive problem of wiring and wire-maintenance among all these points. This would mean that the actual dissectable structure of the brain would diverge from how information travels within it. The brain is complex enough already and we are still stumped by it all.
This divergent independent network of fast linkages would allow a kind of 'wireless neurological network' with instantaneous interconnections and throughput to create what we call thinking and consciousness (two quite different phenomena, neither of which has been proven to exist, at least for many people).
There is nothing outrageous about a suggestion that quantum entanglement may be operating within the brain, except that I am the clearly unqualified person discussing it with you.
What may be unique about my spin (intentional pun) on the subject is that I emphasize the advantages for the highly interconnected requirements of associative processing and memory as differentiated from logical, cognitive, or other operations.
Mayer Spivack


text:
Language course Portuguese C1 (European or Brazilian)
Language: Portuguese
Level: C1
Certificate: CIPLE DIPLE Daple Duple
Course Structure: Group courses, Private lessons, Semi private lessons, Skype
Course Focus: Conversation, Grammar, Standard
Our Target Audience: Adults, Business, Students
Length of Course: 3,5 months, 4 months, 6 months
Lesson Time: Afternoon course, Evening course, Lunchtime, Morning course, Saturday course
Location: Business Clients, Zurich
Read More
Our language course Portuguese C1 (European or Brazilian) offers students the opportunity to master the Portuguese language. Our experienced teachers are native speakers and will provide you with a supportive and rich learning environment, as well as insights into their own culture. The small class size (3-6 students) and up to date teaching methodologies will give you every opportunity to ask questions. You'll also get the chance to speak and practice the language as much as possible.
At the end of your course, you will be able to talk fluently on a range of complex and abstract topics, including the use of idiomatic expressions. You will also be able to write with confidence, using the correct grammar, spelling, and an extensive vocabulary.
After completing one of our courses you can go on to sit the exam for the DAPLE or CELPE-BRAS C1. However, if you feel you would like more practice, we also offer courses for exam preparation.
It is possible to complete an entire level in one course. Depending on the intensity of the course, this can take between 2.5 and 6 months.
These courses are designed for students who have finished B2 and would like to continue to a more advanced level (C1).
We can offer you the flexibility of studying at our centrally located school, in the comfort of your own home, or at your workplace.
Sample quote for a language course Portuguese C1 (European or Brazilian):
Course time: morning/lunch/evening
Number of lessons: 48 lessons of 60 min.
Course fees: 1680 CHF (monthly instalments possible)
Please contact us for a detailed quote and to arrange a free trial lesson!
We pride ourselves on offering quality teaching as well as being flexible in terms of student needs and availability. Let us know your preferences, and we will find the course and time to best suit your schedule.
Our prices are based on certain criteria depending on the course.
A complete price overview can be found here:


text:
Saturday, June 30, 2018
A 5-week Interactive Course
Joy In Everyday Life (Lion) follows Contentment in Everyday Life in the Way of Shambhala class series. If you are also taking the Shambhala Training weekends, it expands the meditation experience of Shambhala Training Level III: Warrior in the World.
As meditation practice expands and we develop trust in basic goodness, we can begin to discover the confidence and personal energy to go forward on the journey. Joining gentleness with discipline leads to a sense of joy. The mahayana teachings on compassion can become the inspiration for a life of bravery and freedom from doubt.
About the Teacher
Shastri Holly Gayley teaches courses on Buddhism in the Religious Studies department at the University of Colorado, Boulder. She has been a practitioner of meditation in the Shambhala community since 1992 and regularly leads meditation workshops. Holly enjoys traveling to nomadic areas of Tibet for her research on contemporary Buddhist movements and trekking in the Himalayas and Rocky Mountains with her dogs, Buster and Poky.
Reading List for this course
Ruling Your World, Ancient Strategies for Modern Life, Sakyong Mipham, Harmony, 2006
The Places That Scare You, Pema Chodron, Element, 2013
About Our Courses
The Way of Shambhala courses are designed for those who don't live near a Shambhala Center, or who need a particular course in order to continue on the path. Each course in the series features a senior Shambhala teacher, an online community of participants, and facilitation by an experienced course leader. Over 6 to 8 weeks, course participants view recorded teachings, then gather in the online learning environment to discuss, contemplate and engage in exercises aimed at deepening their understanding.
When Does the Class Meet?
The course is asynchronous. You may view the recorded talks at your convenience. The recommended schedule is to view one talk each week and complete the associated readings and exercises in the module. There are 5 talks; the course is open for 8 weeks.
Please note that an important aspect of the course involves meeting with another course participant for dialogue. You can arrange live meetings via telephone, an online meeting forum such as Skype, or in person.
How Much Time Does it Take?
Most participants spend 2 to 3 hours per week on the course. The talks average 45 minutes in length. Allow yourself time to do the readings, meditation practices and other assignments. It's a good idea to schedule the time on your calendar as you would for a face-to-face class.
Registration Options
1) Early Bird Discount. The Early Bird course rate of $99 is available until 2 weeks before the course begins. To take the discount at registration, enter the following coupon code: SM3FPZ.
2) Regular Amount. The regular course rate of $125 applies 2 weeks prior to the start date.
3) Patron. The Patron rate of $150 supports our efforts to connect teachers and learners through online programs. In particular, it helps us offer the generosity policy to those in need.
4) Generosity Policy. We want to make the teachings available to all and will work with you to ensure your participation. Click on the Request a Discount link before clicking on the Register Now button, to receive a coupon code to use at checkout.
Centers and Groups, register here. Shambhala teachers, meditation instructors and guides, please write to [email protected] to request a discount.


text:
Twitter's View of the Boston Marathon Bombings
On stage at D: Dive Into Mobile Tuesday afternoon, Twitter's VP of product Michael Sippey talked about the spike in Boston-related tweets following the tragedy and how Twitter's community parses good information from bad.
This transcript has been automatically generated and may not be 100% accurate.
... the ... the ... were response on top of mobile and Noble for spot at the center of the ... more talked about what happiest in Boston um I was was the painters who was acting on the stage ... and does other come in or close the door ... thanks ... um ... I think a lot of people I was on Twitter's I didn't think to look in the other place for information ... um superstore nastiest of how you think yesterday went as a service provider ... before my answer that before answer that aam ... so ... I'm a runner ... and ... aam Avici the short distance runner in on a long distance runner ... aam ... but I've done a few head of community runs ... and there's something about that transition from the ... individual activity of running to a communal activity running that is ... really special when you're out there with a crowd ... and he felt like an especially with Boston such it that such a moment of civic pride for them ... that when that happen yesterday it's devastating ... it's devastating to me like ... the kids that were hurt I have two young daughters I can imagine them ... being at the finish line like waiting for one of their reluctance to cross the finish line and have that happen and so ... the first thing is that like ... my heart goes out to everybody in the city of Boston and cassette was this awful HSAs awful ... aam ... our CEO to costs low said a whole bunch of times when events happen in the world they also happen on Twitter ... and that was the case yesterday on a whole bunch of people came ... to Twitter to talk about what happened and we saw the listing things ... happen yesterday the first is that ... we saw a aam ... two hundred x increase and the use of the word Boston ... and tweets yesterday and weighed expand yet awaiting you'd expect ... aam ... but we also saw ... a peak in the use of the word help ... over the last hundred Navy days was the height of the last hundred years ... aam and that was from people if you're following any vast eggs are doing a search queries on last year Boston Marathon ... was people offering help ... um people are ... responding to the base of the prison the first responders to be the people that were never going into hell ... an essentially for us ... it's ... that were ... obviously but proud to offer that service to be a place where people can talk about things and and actually experience of its so it's important for people like me inexorably autism are the treasures of personalized service to my Twitter experience is different than yours no one else is here ... um ... that said I I stayed seated serve repeated this a deer hit allots starting early yesterday afternoon from last time this morning where ... it ... did Boston these shows Twitter is best ... says immediate source of information and it's it's ... it's awesome and all this information included in the worlds and in really quickly ... and also in the works right ... immediately there's that information is people say stupid Stoppers people telling notable for saying stupid stuff ... um ... you guys done anymore thinking about what their ways were weak in ... certain ... sort the content or at least point people in different directions in on the Power user friendly thousand plus people but a lot of people that are trying to reach right ... this is all pretty knew that he thought about ways to Sir to ... sift through the content on the New Year user's behalf so all all come into custody for two decks into question ... the first is the ... um so Twitter as an open platform for communication ... he'll have ... a lot of people spreading like real-time term information also have people like that about actor Sobel spread false information ... I think you saw in love stories coming out of yesterday is that ... Twitter is also ... really good for journalists and for citizens to essentially route out the bad information an expose of his back ... almost as fast as is being spread so ... and actually happen yesterday as I was all ... things with Boston ... aam it didn't use the current that's the max that mechanism exists it's certain to someone ... John Herman but that self cleaning up what he think ... that's built we like the way it is it's good ... so I like that that though the best with this that that that thing here's to the second part of your question I think it's ... really about ... how to we actually starts the Cunniff filter into the user to user experience based on your pants quarter ... here's how we think about that first of all it's a ... it's a pretty simple service right so ... you have bought the fall people ... their sweet show up in real time in reverse chronological order ... and if there's too much noise or people that you know one in your home time on ... you want follow them ... so that's one is that putting the user putting the user in control of what their own timeline experiences is ... a fundamental part of the product ... and it's really important how we think about the service ... the second piece is ... when we spent the last couple of years made a big investment in our search irrelevance infrastructure ... aam and real time search ... has done incredibly powerful on Twitter ... in addition to archive search and set to be able to go back in time ... aam you can now search over the entire history of ... the corpus of tweets ... the the the thing that we're doing is using the signal that we have ... about the people there creating content about being gay spent with those tweets ... and about on your individual history interaction with Twitter ... in order to present you a better search experience in a better Discover timeline or so Nasser insertion discovered a second but that is that basic mechanism is running into the in the beginning of that answer that it's all we want to feel ... that by air and turn them on or ... off its been that way since they watched back in two thousand suspects ... um then again I'm a power user in mind ... so to provide a good idea what I wanted to anyone I'd get stock a lot of ... Kyle these guys are ... I have no interest in the BMA is that suddenly brought people my feeder really talk about that the images I wish they would stop ... or I can send them offer friendship and Dow ... of more whatever is some eleven version ... to the complains about sports or whether days and I'm sure sleep who are calling a thousand people also have some more questions ... do you think about averages and again it's reverse chronological it's all in order givers think there are ways we could ... change this doesn't have to be the way was building was built for really basic phones six years that when we think about we think about that all the time aam and look into ways to tweak a present ... at present time I experienced ... on that the Discover Tavern the product of time ... on mobile and others on the web ... is ... is some experiments were trying their two cents would present you ... relevant content ... that is from some deeply fallen from a lot of people's overnight that your answer disagreed that the star answer to Twitter where basic enters the arena section and were were always doing experiments and looking at ... ways we can


text:
First Look: Southeast Asian Cocktails at The Union Bar in Vancouver BC
The Union Bar is named after its location on Union Street in Vancouver, BC. Ask a Vancouverite where Union Street is, and you may receive a dumbfounded look in response. Explain that it's where the Jimi Hendrix's shrine is, and you may get a few acknowledging "aahs." If you elaborate that it's "that sketchy street in Chinatown next to the Georgia Viaduct", most locals will be able to pinpoint it.
Until recently, Union Street was known for little more than where not to park when it gets dark out. But now there's The Union Bar.
Executive chef Lisa Henderson also owns Latitude on Main Street, which focuses on South American fare and has an impressive tequila selection. Her new spot, the Union Bar, serves casual Southeast Asian specialties such as Malaysian satays, Vietnamese banh mi, and Indonesian nasi goreng to snack on alongside an inventive cocktail list.
Head barman Arthur Wynne was an award-winning coffee barista before switching gear to become a bartender. Wynne, who's originally from the Phillipines, brings warm, tropical flavors into his creations, relying on the distinct scents of fresh herbs such as Thai basil and roots such as lemongrass and galangal to set his cocktails apart.
The Pandan Fashioned Cocktail hits the tongue with familiar bourbon and bitters, followed by the nutty pandan flavor that lingers. This simple drink is made with only 3 ingredients, including a pandan-infused simple syrup, but it's surprisingly complex.
The other cocktails on the menu are lighter and less liquor-forward. The Khe Sanh Sour, a rum cocktail shaken with ginger, lime, chili water, and eggwhite for body, is easy-sipping and smooth. The subtle heat from the chili creeps up slowly as the glass empties. The lime leaf placed at nose level provides a citrusy and floral aroma.
Arthur only uses fresh fruit—these aren't the syrupy, artificially-flavored drinks that one might associate with "tropical cocktails". Take the banga (which means "jar" in Filipino)—these are literally drinks made with a jar and a stick, inspired by the fresh fruit drinks served in plastic bags in Asia. The bartender combines liquor with a variety of fruit and herbs in a jar, muddles it up, twists on the lid and shakes it hard, then serves it with crushed ice and a straw.
Going along the line of lighter cocktails, the Oolong Island Iced Bubble Tea is a rum iced tea shaken with calamansi vinegar for tang and savoriness. Barely sweetened, the cold brewed tea stands its ground. The tiny coconut bubbles (made from the spherification method) gives the drink an amusing texture without screaming "molecular mixology".
Check out the slideshow for a closer look at Union Bar's drinks, plus a few easy recipes to make at home.
The Union Bar
219 Union Street, Vancouver, British Columbia (map) 604-568-3230; theunionbar.ca
All products linked here have been independently selected by our editors. We may earn a commission on purchases, as described in our affiliate policy.


text:
Good morning. It is time for me to make my bi Annual Motorcycle purchase.
My Past 7 years of bikes:
2006 Honda CBR 600RR
2009 Yamaha R1
2009 Triumph Speed Triple
Prior to the CBR, I have nothing amazing to report, dirt bikes, some very old BMW's etc.
Of the bikes listed above, the R1 was the worst, and I liked the others equally. Speed Triple was a lot of fun, but lacked things the K1200R had, K1200R was a little too heavy, CBR was amazing all around, but just didnt quite have the low end that I wanted.
This time around I am looking for a bike that I could ride on the occasional road trip, but would be ridden primarily to work (60 mile round trip) 3-4 days a week, and weekends. Probably will rarely see the track. I have ridden a modified s1000rr, and really enjoyed it, but only road a few miles, nothing major. I have a few questions for you owners and maybe that will help me decide.
1. Why are they not holding value well? I have seen a few 2010's with low miles and all of the add ons for just over $10k
2. Rumors for refresh soon? I dug and dug, but nothing really solid supports a refresh. It seems like BMW likes to keep body styles for years as well.
3.Do any of you travel at all on your bike? I read the guy's story that went from texas to Baja and back, but maybe he was just a trooper. How comfortable are these for more than a few miles?
4.Riding 2 up? My wife hates riding on motorcycles, so I don't know that this is a huge issue, but I am curious if many or any of you ride with a passenger from time to time?
5. Issues?
The other bikes I am considering are completely unrelated. If I get a super sport bike, this is the bike I want.
The other considerations are:
1.2012 Triumph Speed Triple R
3.Ducati Hypermotard
4.Ducati Streetfighter
Thanks for reading my wall of text. I appreciate any input.


text:
Roboexotica Vienna
Roboexotica, the festival for cocktail robotics, takes place in Vienna, Austria.
Labels: connectivity, event, Vienna
A weblog for dropouts, ex-patriats and dreamers.
No need to load my complete blog everytime you visit here. Just take a look at http://feedly.com and get your personalized RSS reader from any browser or mobile device.
Quote from Lore Sjöberg: Creating your own blog is about as easy as creating your own urine, and you're about as likely to find someone else interested in it ;-)
Labels: connectivity, event, Vienna


text:
9th Annual Goodguys Lone Star Nationals - Texas Two-Step
Trucks took center stage at the 9th Annual Goodguys Lone Star Nationals
No doubt about it--Texas is truck country. Take a cruise down any Lone Star highway and you'll quickly see that pick-'em-up trucks are the preferred mode of transportation for real ranch-hands and urban cowboys alike. So it's only fitting that one of the most prestigious classic truck awards of the year is handed out at an event in Texas.
The award is the Goodguys Truck of the Year, and the event is the Lone Star Nationals, which was held October 27-28 (rescheduled from October 6-7) at Texas Motor Speedway in Fort Worth. And even though 2001 marked only the second year for Truck of the Year honors, it still drew a host of heavy hitters to vie for the title (actually two titles--one for pre-'53 trucks and another for '53-and-newer trucks). One of the ten finalist trucks (five for each category) came all the way from Canada by way of California. Another made the trek from Arizona. A third came from Las Vegas, Nevada. All ten pickups were great rides, but only two could return home with the trophies, the bragging rights, and the $1,000 cash prize.
Truck of the Year judging took a little twist at the 2001 event, as the folks at Goodguys decided to get the participants involved. First, a panel of judges including Goodguys representatives and a CLASSIC TRUCKS staffer narrowed the field down to five trucks in each group. Then the finalists themselves were asked to participate in the final judging, with "Early" finalists voting on the "Late" trucks, and "Late" finalists voting on the "Early" trucks. Competition was close, but in the end the honors went to Steve Sandlin's '48 Chevy pickup and Dave Kimmerle's '56 F-100.
Even if you weren't a contender for Truck of the Year, the Lone Star Nationals held plenty of appeal. With around 1,500 vehicles on hand from at least half a dozen states, there was a lot of old iron to see. There was also a sizeable swap meet at the event, as well as a bunch of commercial vendors selling aftermarket parts to help keep that on-going project progressing. You could even rent a ride in a NASCAR machine, with a professional driver taking you for a 140 mph spin. But the coolest part of all had to be the track cruise Saturday evening, where participants were allowed to test out their rides on the banked turns of Texas Motor Speedway.
Trick trucks, cool cars, and big-time fun. It's all standard fare for a Goodguys event in the Lone Star State. See y'all next year!


text: Dog collars: most dogs have them, but not every dog gets our unique dog collars and unique dog leashes. Our designer dog collars are the epitome of fancy dog collars. Many dog collars we offer are Swarovsky crystal dog collars. We also carry dog collars and leashes that are fashion dog collars, training dog collars, leather dog collars, jeweled dog collars, pewter dog collars and more!


text:
I Want One of Those: Take-a-Breather
When asthma strikes, people can regain their breath by using an effective but inconvenient electric nebulizer, a small but inefficient metered dose inhaler (MDI), or an MDI that has a long spacer attached to it to ensure that the medication reaches the lungs. Take-a-Breather improves on the MDI by adding a collapsible spacer and dual-flow mouthpiece. The telescoping spacer keeps the MDI pocket-size. The mouthpiece allows users to breath naturally, like using a nebulizer. Zakieh Bigio '10, Betsy Dain-Owens '10, Catherine Emil '10, Sarah Feldmann '11, and Sarah Rocio '10 developed Take-a-Breather for ENGS 21: Introduction to Engineering. Their teaching assistant was Ashley Heist '08 Th'09.
Categories: The Great Hall, I Want One of Thosecomments powered by Disqus


text:
Current drugs used to treat heart failure and arrhythmias (irregular heartbeat) have limited effectiveness and have side effects. New basic science findings from a University of Iowa study suggest a way that treatments could potentially be refined so that they work better and target only key heart-related mechanisms.
The team, which included researchers from Vanderbilt University, showed in theory that it might be possible to use drugs that maintain the positive effects on heart function of a known enzyme called calmodulin kinase II (CaM kinase) while reducing its negative effects. The findings were published the week of March 1 in the Early Online Edition of the Proceedings of the National Academy of Sciences.
anderson"CaM kinase helps regulate calcium, which is essential to heart function, but CaM kinase's calcium connection also can play a role in electrical problems that lead to irregular heart beats and cell death. This new finding suggests a specific way to keep the wanted CaM kinase effects but at the same time eliminate the bad effects," said Mark E. Anderson, M.D., Ph.D., professor and head of internal medicine at the University of Iowa Roy J. and Lucille A. Carver College of Medicine.
Anderson said that heart failure is among the most common discharge diagnoses for patients leaving hospital. "Most patients with heart failure are at risk of sudden death. Figuring out how and why heart failure happens is a major goal for academic medicine," Anderson said.
CaM kinase adds phosphate groups to other proteins — a process known as phosphorylation. This process can activate proteins and set in motion or sustain cell activity.
"The study showed, surprisingly, the importance of CaM kinase's effect on two particular amino acid targets among the thousands of amino acids that make up protein targets for phosphorylation by CaM kinase. Controlling these targets might prevent the 'ripple effect' of other molecular events that result in arrhythmia and cell death," said Anderson, who also is a member of the University of Iowa Heart and Vascular Center and holds the Francois Abboud Chair in Internal Medicine.
Using rabbit heart cells, which behave much like human heart cells, the team showed that if CaM kinase is prevented from interacting with a protein that regulates calcium channels, negative effects, including cell death, do not occur. Specifically, they showed it was possible to either block the specific site on the protein where CaM kinase binds or block the ability of CaM kinase to perform phosphorylation on the protein.
In both cases, blocking the action of CaM kinase prevented too much calcium activity, which can be harmful.
"CaM kinase is needed to maintain calcium channel function, which allows the heart to contract. But too much CaM kinase, and consequently too much calcium entry into heart cells, causes electrical instability and other downstream molecular problems that can lead to cell overload and cell death, which causes heart failure," Anderson said.
Anderson said a next step is to try to develop drugs to prevent the unwanted CaM kinase effects.
The study's primary author was Olha Koval, Ph.D., UI postdoctoral research scholar in internal medicine. Other major UI contributors included Thomas Hund, Ph.D., associate in cardiology, and Peter Mohler, Ph.D., associate professor of internal medicine.
Anderson is a named inventor on a patent owned by Stanford University claiming to treat arrhythmias by CaM kinase inhibition.
NOTE TO EDITORS: "Fondation" in the name "Fondation Leducq" is spelled without a "u."


text:
I love the Psalms because they are both prayers and songs. As I've been reading one each morning during my prayer time, I find that a Psalm of my own – a Psalm of both lamentation and praise – is forming in my mind. So I thought I'd write it down and post it here for Thankful Thursday.
A Psalm of Lament and Thanksgiving
Oh Lord, my God, how long
will You stand by as cancer
strikes those I love,
as pain and sadness
are all around me
How long must we endure
this broken world
sometimes wondering
where You are,
where is Your promised refuge
Tears fall upon my pillow
as I long for salvation,
for healing and no pain
in the lives of my loved ones
my friends, my family
Your children
Still I praise You, Oh Lord
I trust in Your promises
clinging to faith and hope
found only in You
I lift to Your throne
Your children in need
Your faithfulness endures
beyond what I can see
with eyes blinded by pain
Still I know, I believe
Your grace and mercy
are more than this world needs
May Your name be exalted
Your grace be embraced
Your love be never-ending
Your peace from me radiate
So that those in need
will know You and praise You
forever and ever


text: Deprecated: mysql_connect(): The mysql extension is deprecated and will be removed in the future: use mysqli or PDO instead in /nfs/c02/h07/mnt/45830/domains/shop.sushigoi.com.au/html/includes/functions/database.php on line 19 Warning: session_start(): Cannot send session cache limiter - headers already sent (output started at /nfs/c02/h07/mnt/45830/domains/shop.sushigoi.com.au/html/includes/functions/database.php:19) in /nfs/c02/h07/mnt/45830/domains/shop.sushigoi.com.au/html/includes/functions/sessions.php on line 102 - SUSHIGOI - Languages: Home Page What's New? Specials Reviews Contacts Shoping Cart:Now in your cart 2 items Welcome to - SUSHIGOI - Welcome Guest! Would you like to log yourself in? Or would you prefer to create an account? New Products For July seafood salad1 "Salmon, prawn, cuttle fi... Our Price: 0 DetailsAdd to Cart salmon salad1 "Salmon, mix salad and se... Our Price: 0 DetailsAdd to Cart chuka shimeji1 "Mushroon salad (60 gr)&q... Our Price: 0 DetailsAdd to Cart green tea1 "Japanese green tea (no s... Our Price: 0 DetailsAdd to Cart Main Menu Home What's New? Specials Reviews Advanced Search Log in Create an Account Shipping & Returns Contacts Copyright © 2020 - SUSHIGOI - Privacy Notice | Conditions of Use.