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When you're behind the wheel of a Sports Car, your focus is on the road. On the sensation and pleasure of driving. To ensure that you are able to enjoy the experience to the full,
Thanks to real-time information and a seamless connection,
These features are just a small selection of all the functions and services that
¹The basis for
We provide a festival initiator, an artist and an entrepreneur the opportunity to explore the intelligent connected services available from
© 2020 Dr. Ing. h.c. F.
* Data determined in accordance with the measurement method required by law. Since 1 September 2017 certain new cars have been type approved in accordance with the Worldwide Harmonised Light Vehicles Test Procedure (WLTP), a more realistic test procedure to measure fuel/electricity consumption and CO₂ emissions. As of 1 September 2018 the WLTP replaced the New European Driving Cycle (NEDC). Due to the more realistic test conditions, the fuel/electricity consumption and CO₂ emission values determined in accordance with the WLTP will, in many cases, be higher than those determined in accordance with the NEDC. This may lead to corresponding changes in vehicle taxation from 1 September 2018. You can find more information on the difference between WLTP and NEDC at www.porsche.com/wltp.
Currently, we are still obliged to provide the NEDC values, regardless of the type approval process used. The additional reporting of the WLTP values is voluntary until their obligatory use. As far as new cars (which are type approved in accordance with the WLTP) are concerned, the NEDC values will, therefore, be derived from the WLTP values during the transition period. To the extent that NEDC values are given as ranges, these do not relate to a single, individual car and do not constitute part of the offer. They are intended solely as a means of comparing different types of vehicle. Extra features and accessories (attachments, tyre formats, etc.) can change relevant vehicle parameters such as weight, rolling resistance and aerodynamics and, in addition to weather and traffic conditions, as well as individual handling, can affect the fuel/electricity consumption, CO₂ emissions and performance values of a car.
** Important information about the all-electric


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Fossil Fighters Cheats[ NDS ]
Search "team" in Fossil Fighters Tags :
Unlockable - Team Skills
In Bottomsup Bay, in one room on the pirate ship, there is a chest containing a Team Skill book. If you grab it, you will see that every one of your vivosaurs has a red move, that may or may not be unavailable in battle. These red moves are team skills. To be able to use them, make a team of vivosaurs that either is the same type or has the same diet (e.g. carnivore, herbivore, etc.). The type is visible in the VMM and the menu, and the diet is visible in the Fossil Museum or on the computer in your hotel room or by the dock.
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subset: commoncrawl


text:
Hola ENOpians!
Is it getting breezy where you are? Are those fall leaves spiraling in the chilly winds? Keep that hiney warm with the HotSpot!
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Dimensions (unpacked):
It folds up in no time and all and is slender enough to fit right in the front pocket of your pack! Enjoy!


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- In a microwavable bowl, combine eggs and ingredients A and mix briefly.
- Cover the bowl with plastic wrap, cook in micro at 600w for 1 min and 30 seconds. Take out, mix with a whisk.
- Return to micro, cook for 1 mins. Take out, mix with a whisk.
- Return to micro, cook for 30 seconds. Take out, mix with a whisk. Repeat this step one more time.
- Then, add in crab meat and stick. Stir to mix.
- Grease pan with cooking oil, transfer egg mixture into pan.
- Steam at 90C for 20-25 minutes,cool completely.
- Invert steamed egg onto a chopping board, cut into desired shape and size.
Steamed Egg With Crab [Easy Steam-Oven Recipe]
Comments :
- Anonymous said... on
- 12 April, 2012 15:02
The dish look so delicious!! What can I do if I do not have microwave? Thank you! (:
- Little blue said... on
- 12 April, 2012 22:05
Yummy yummy!
- MeRy said... on
- 13 April, 2012 00:23
looks yummy...
wat is mirin? and I don't have microwave at home? any other way to cook this dish?
- Anonymous said... on
- 13 April, 2012 10:14
Why do we need to microwve it and whisk 3 times?
And how do I know the final step of the temp at 90 degrees? Must it Also be at 90 degree s?
- D said... on
- 13 April, 2012 12:24
What is a steam-oven?
- Lydia said... on
- 13 April, 2012 14:49
Hi Claire, Mery & Z,
You can heat and whisk the egg mixture over a pot of hot water (double boiler) until the it is thickened. Then you add in crab meat/stick, and steam on low heat in a steamer.
- Reason for heating the egg mixture before steaming is to prevent crab meat/crab stick from sitting in the bottom of the pan.
Mirin is sweetened rice wine used in Japanese cooking. If you dont have you can add a small amount of sugar.
It does not need to be at 90deg but not more than 90deg. If the temperature is too high the steamed egg will have rough texture and full of little holes.
Steam oven is an oven combined with steamer. Mine is Micro+Oven+steamer. The oven and steamer can also be operated together for healty cooking and bread making. It is still new in the market I think.
- julien said... on
- 14 April, 2012 11:06
looks so good! i wish i could make this! sounds simple too, just need to buy the ingredients! what about the other dishes?? they also look so good, makes me want to make everything in the picture and serve on that fancy plate. Will have to look for a fancy plate like that though D:
- Anonymous said... on
- 15 April, 2012 11:45
Thanks for reply. One more question - when you invert to remove the egg, how to remove it since the egg would stick to the pan/ bowl after steaming?
- Lydia said... on
- 15 April, 2012 23:10
Perhaps you missed out step 6 in the method. :D Happy cooking and hope to see your steamed egg soon.
- Anonymous said... on
- 16 April, 2012 19:33
Apart from preventing the crab meat from sitting onto bottom of the pan, what is the difference to the egg mixture if I whisk it and heating at the same time versus whisking at room temperature?
- Lydia said... on
- 16 April, 2012 22:40
Heating and whisk (briefly) is to cook the egg mixture evenly, if heating without wisking it will be well done at bottom and surface.
Once it is thicken (not well done) crab meat will be distributed evenly when added.
As wisking without heating, eggs mixture will contains too much air bubble inside and expand rapidly when steaming. Also, crab meat will be at the bottom of the pan.
Hope I've answered your question.
- Anonymous said... on
- 16 April, 2012 23:41
Wow.. That's a great insight! I never would be able to figure that without your explanation!
Yes, understand now thanks!
- Joan said... on
- 18 April, 2012 18:03
creative and looks delicious! Yumyum!


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Everyone comes to franchise ownership for different reasons. Some franchisees have always dreamed of owning their own business and a Visiting Angels home care franchise provided the opportunity they wanted to peruse. Others came to franchise ownership because of changes in their previous careers or industry. Still others came to Visiting Angels through personal experiences with the need for at home care services. Whatever the reason, we are proud to have so many wonderful, dedicated individuals as part of the Visiting Angels family. We invite you to read about some of the reasons why our franchisees chose a Visiting Angels franchise as their path to personal fulfillment and professional success.
One of the most popular reasons for choosing a franchise, as opposed to striking out on your own, is the advantage of having a nationally known brand behind you. Visiting Angels home care franchise owners don't have to spend time or money to establish name recognition in their community. For Peg Pickett, of Visiting Angels Orlando, this was a real selling point. Peg explains, "We go out and people say 'Wow, we've heard about you [Visiting Angels]. You guys do a great job,' and part of that is because of the branding the corporate office does for us. If you're going out to close a client, if you're out marketing or networking, you're getting the important things that you need [from Visiting Angels Corp] to make your business successful."
Many people new to the franchise environment find the support they receive from the home office to be especially helpful as they are learning the ropes of business ownership. Sheryl Ross, of Visiting Angels Los Angeles, explains how individual support meetings with the home office team help her to solve everyday challenges. "If you have problems with caregivers, you want to know how to grow your business, whatever you need, you get two hours of their time [in the one-on-one meetings]. They [Visiting Angels Corp] have all the answers and it's a great resource."
Lydia Roos, owner of Visiting Angels Tucson, also chose Visiting Angels because of the support and experience of the home office team. Lydia explains, "What a wonderful group of people supporting the franchisees...I get many leads a week [from Visiting Angels Corp] and they are converted into clients for us…..these are clients that are truly interested in home care. I just ended my second year [as a Visiting Angels franchise owner] and we have had tremendous growth….the support of the franchise is amazing."
If you are in the process of choosing a home care franchise, consider the fact that Visiting Angels is known for its commitment to providing superior support to franchise owners. Many entrepreneurs choose Visiting Angels for its comprehensive support system that includes traditional and online marketing strategies; national, regional and one-on-one coaching meetings and conferences; and protected territories and affordable startup costs. With Visiting Angels, you can be confident the home office is committed to helping you achieve your dreams of business ownership and success. "The thing that I like the most…about this franchise [Visiting Angels] is the support that we get from our home office. The thing they [owners of Visiting Angels] tell us all the time is do the care as you should, do the best care you can and the money will come," explains Patty Andresen of Visiting Angels Newport News.
Choosing a home care franchise to invest your time and money in is a big decision. Choose a home care franchise that has been providing superior care to seniors and the disabled since 1998. Choose a Visiting Angels home care franchise. With more than 450 franchise locations around the country, we can help you find success with a business that brings professional and personal fulfillment.
Learn more about our home care franchise opportunities and about purchasing a Visiting Angels home care franchise.
Other Articles
You were such a comfort to me and my grandmother before her death. Your caregivers are a godsend!
You were such a comfort to me and my grandmother before her death. Your caregivers are a godsend!


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Dislike outages? Wait until tomorrow's high winds
People are reporting that power is out on parts of the UVA Grounds, as Dominion Virginia Power reports a 242-customer outage in that area, and quirky UVA radio station WTJU is apparently without power in the middle of its annual rock marathon. However, today's outage could be just a presage for further outages tomorrow.
Charlottesville Fire Chief Charles Werner has contacted media to let them know that he's expecting repeated gusts over 40miles per hour on Saturday, February 19, with some gusts topping 60mph.
"Many downed trees and large limbs are possible," says Werner in an email, "and even the areas that aren't under the watch for the worst of it will be seeing very gusty winds."


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One of the most dreaded days of the year is here: Friday the 13th.
While many of us might be quick to pull the covers back over our heads, do we really know what makes this such an unlucky day?
No one really knows. In fact, there are a few different stories that could have played a part in making this one of the most feared days of the year.
U.S. & World
According to timeanddate.com, the day was first documented in writing in a biography of Italian composer Gioachino Rossini who died on a Friday the 13th. Some people believe there's a link to Biblical times — there were 13 people at the Last Supper and the crucifixion took place on a Friday.
The fear of Friday the 13th really does exist, according to Mathworld. It's called "paraskevidekatriaphobia" — from the Greek words "Paraskevi" for Friday and "dekatreis" for 13. Mathworld says it may be one of the widest spread superstitions in the United States.
Friday the 13th can occur three times in a calendar year. In fact, this is the last one for 2015. The month must begin on a Sunday in order to have a Friday the 13th in any month.
If you just can't fathom the thought of leaving the house, here are a few known facts about Friday the 13th that may make it easier to cope.
Italians believe the number 17 is unlucky, making Friday the 17th an unlucky day.
The original "Friday the 13th" film was set on Friday June 13, 1979. But that date really fell on a Wednesday. It was also a successful franchise.
A German study explored the relationship between Friday the 13th, and blood loss and hospital visits. The conclusion? There is none.
"Our data indicate that such beliefs are myths far beyond reality," the study said.


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Beginning this week, Jacob Ciocci will be touring the west and east coast with his videos and a new performance, tour dates here.
the peace tape (2009) - Jacob Ciocci
The Question of Freedom at the Open Video Conference
Does free video uploading and downloading equal democracy? I asked myself this question during the recent Open Video Conference, organized by the Information Society Project at the Yale Law School and the Open Video Alliance, an umbrella coalition for the development of an "open video ecosystem": a "movement to promote free expression and innovation in online video." Conference sponsors include Mozilla, Redhat, Intelligent Television, and Livestream. The conference was held at New York University's Vanderbilt Hall, home of the NYU Law School from June 19-21, 2009. I attended several of the panels at the conference, although it was primarily Yochai Benkler's opening keynote that was of concern.
Take Care of Yourself (2007) - Sophie Calle
In this "tour de force of feminine responses…executed in a wild range of media," Sophie Calle orchestrates a virtual chorus of women's interpretations and assessments of a breakup letter she received in an email. In photographic portraits, textual analysis, and filmed performances, the show presents a seemingly exhaustive compendium with contributions ranging from a clairvoyant's response to a scientific study, a children's fairytale to a Talmudic exegesis, among many others. Examining the conditions and possibilities of human emotions, Take Care of Yourself opens up ideas about love and heartache, gender and intimacy, labor and identity. 107 women (including a parrot) from the realms of anthropology, criminology, philosophy, psychiatry, theater, opera, soap opera and beyond each take on this letter, reading and re-reading it, performing it, transforming it, and pursuing the emotions it contains and elicits.
For an interview with Sophie Calle, where she discusses the exhibition of Take Care of Yourself at the French Pavilion in the 2007 Venice Biennale, go here.
I'll Replace You (2008) - Jennifer and Kevin McCoy
I'll Replace You from Jennifer & Kevin McCoy on Vimeo.
This film is an experiment in outsourcing everyday life. In it we hired 50 actors to take over all aspects of our daily routines and roles as parents, spouses, professors, artists and friends. The actors play opposite their real counterparts - our kids, our students, our friends, in our studio, presenting our work.
F'Book: What my Friends are doing on facebook (2009) - Lee Walton
Katie Minton is monochromatic. from lee Walton on Vimeo.
Rick Silva is self-editing. from lee Walton on Vimeo.
In Lee Walton's most recent project, he will perform what his Friends on Facebook are doing.
On Tour
In June I traveled through southeastern Europe from Venice to Athens, where I'm looking at art and blogging. Part three of the travelogue is about Belgrade, Serbia.
With a population of two million, Belgrade is twice as big as Zagreb, which is thrice as big as Ljubljana, but the sizes of these three cities have a paradoxically inverse relationship to their cultural infrastructure, particularly at the intersection of art and technology. While little Ljubljana had enough events to fill my schedule for four days, Zagreb's handful of galleries were in a summer slumber. But organizations were actually there, even if hibernating, while Belgrade had nothing. Many attributed that to the smaller country's attempt to find a niche or a brand for itself in Europe's crowded contemporary art world. "New media in Slovenia was as a more or less organized way of deterritorialization from the ex-Yugoslavian context, a systematic attempt 'to be more serious than the system itself,'" said Maja Ciric, a Serbian curator, citing Zizek. "But in Belgrade the new media paradigm is self-driven and performed individually."
Belgrade had a small but active demoscene in the 1990s, which gave rise to one of the most interesting art collectives in the former Yugoslavia, Kosmoplovci (pronounced "kos-mo-PLOV-tsee"). The name means something like astronauts or space sailors, and comes from a 1970s do-it-yourself science and technology magazine that some demoscene friends found at a flea market in the early '90s. The members of Kosmoplovci are fond of rummaging through the past, and their varied output—which includes internet works, videos, music, comics, and books—usually involves allusion and found media. Satelitska Stanica is based on an old 8mm film extolling a joint project with Japan to ...
Ivan Sutherland : Sketchpad Demo
This video is a TV show made about the software Ivan Sutherland developed in his 1963 thesis at MIT's Lincoln Labs, "Sketchpad, A Man-Machine Graphical Communication System", described as one of the most influential computer programs ever written. This work was seminal in Human-Computer Interaction, Graphics and Graphical User Interfaces (GUIs), Computer Aided Design (CAD), and contraint/object-oriented programming. While watching this video, remember that the TX-2 computer (built circa 1958) on which the software ran was built from discrete transistors (not integrated circuits -it was room-sized) and contained just 64K of 36-bit words (~272k bytes).


text: Product Information: With multiple colors of Gebera in one bouquet, you can let the other person know about your fathomless love. It is a suitable gift for any occasion or event.Send this beautiful vase filled available with 10, 15, 20 Pcs. Delivery Information: Same Day Delivery available in all Major Cities of India. Please contact firstname.lastname@example.com or Whats app No: 9007738601 for delivery location confirmation. Normal Delivery time is 9 am to 7 pm. In case of any any specific time delivery please mention it to ORDER COMMENT or mail it to email@example.com. Flowers are perishable in nature, so delivery will be attempted only once. Image of product is indicative in nature. Actual product may vary slightly in design as per the location and availability. Sometime same colour Flower is not available in all the location and in all season. In that case flower with other colour would be delivered but it will be definitely intimated to customers. Product is hand delivered item and cannot be sent by courier.


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A speculum examination and a bimanual pelvic examination are often done together. These examinations are used to evaluate the overall health of a woman's reproductive organs.
For these tests, the woman lies on her back on an examination table with her legs parted and her feet resting off to the side in devices called stirrups.
For the speculum examination, the health professional inserts an instrument called a speculum into the woman's vagina. The speculum helps to spread apart the walls of the vagina, allowing the health professional to see the cervix and the walls of the vagina. Samples of tissue may also be collected for testing.
A bimanual pelvic examination often follows the speculum examination. It is done to check a woman's pelvic organs (such as the uterus and ovaries). The speculum is removed and the health professional inserts two gloved, lubricated fingers into the woman's vagina while pressing on her abdomen with the other hand (bimanual means with two hands). This allows the health professional to feel where and how large the woman's pelvic organs are. The woman can tell the health professional if it hurts when her organs are touched or moved.
Current as of: November 8, 2019
Author: Healthwise Staff
Medical Review:Adam Husney MD - Family Medicine & Sarah Marshall MD - Family Medicine & Martin J. Gabica MD - Family Medicine & Kathleen Romito MD - Family Medicine & Femi Olatunbosun MB, FRCSC - Obstetrics and Gynecology
This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.
To learn more about Healthwise, visit Healthwise.org.
© 1995-2020 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.


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Thursday, July 1, 2010
Each benchmark is presented with a description, graph, and analysis tied to its related program. The majority of the benchmarks use a comparison of data from the District and other jurisdictions over time; thus one can compare each period of time and observe the trend (if any). Several indicators do not include data from other jurisdictions and only display the trend of D.C. results over time.


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November 07, 2013
By Kenneth D. Miller
Assistant Managing Editor
The often quiet albeit very much respected veteran broadcast-journalist who spent 13 years as Managing Editor and Sports Editor of the Los Angeles Sentinel, Ron Dungee died on Monday Nov. 4 at Cedars Sinai Hospital. He was 75.
Dungee was admitted to the hospital on Friday Nov. 1 after suffering a second bout of pneumonia.
Known for his easy going personality, Dungee was the consummate professional and after arriving to the west coast from his birth place of Chicago, his impression in television, radio and print journalism was made.
He transformed from a small time sign painter in Chicago to a veteran of the broadcasting and journalism field for more than three decades beginning in Las Vegas in 1970, where he served as the news anchor for KORK TV and then taught broadcasting at the University of Las Vegas at Nevada.
A former member of the Air Force, where he committed four years of his life, Dungee then came to Los Angeles where he became a staple on radio in 1971 at KGFJ, where he was news and sports director and continued in either one or both of those capacities at KEARTH, KDAY, KKTT, KJLH, KFWB, KUTE and then at Willie Davis owned KACE.
Dungee joined the Sentinel in 1990 as a proof reader and was promoted to Managing Editor and Sports Editor until he left in 2002 to work as press secretary for Congresswoman Maxine Waters. He worked for Rep. Waters for two years before retiring.
"Ron Dungee exemplified intelligence, professionalism and courtesy in a manner that can not be duplicated," said Sentinel Executive Publisher Danny J. Bakewell Sr. in a statement. "The Sentinel Family will be forever grateful to his commitment to excellence in the field of journalism and our immediate thoughts and prayers go out to his wife and family."
He was married to his wife Mary Davis-Dungee for 27 years and is survived by Tanya Brown, Waynette Davis, Jenifer Dungee-Thompson and John Davis.
"I will miss his unbelievable intelligence and dry sense of humor," said his widow. He was very quiet and he loved people," Mrs. Dungee added.
A private memorial service will be held for Ron Dungee at Forrest Lawn in Glendale.


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Issues and tips relating to oils, grease and lubrication for old motorcycles.
Use this control to limit the display of threads to those newer than the specified time frame.
Allows you to choose the data by which the thread list will be sorted.
Order threads in...
Note: when sorting by date, 'descending order' will show the newest results first.
Forum Rules


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NEW DELHI, April 9 (UPI) -- Facebook users in India reached the 100 million mark, the company said Wednesday, now its second-largest market after the United States.
The social networking business has had India in its plans to make it the world's largest market in terms of users. The fast pace of growth in mobile and data services in India made the target easier; nearly 84 percent of Facebook users in India access Facebook on mobile devices.
"We've only just begun. Facebook's mission is to give people the power to share," said Facebook India's Kevin D'Souza, noting a partnership, internet.org, with the aim of connecting five billion people around the world.
"India is an exciting market for us because we are at the start of the data boom. We have found that the primary reason for Indians to subscribe to data is to get on Facebook," said Facebook Vice President Vaughan Smith.
A challenge for the company, though, is to grow its advertising revenue in line with the user growth.
"When we started in India four years ago, people asked whether someone really advertised on our platform. Now marketers use Facebook as a strong platform," said Kirthiga Reddy, head of Facebook India.
[Hindu Business Line]


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The Bishop is the first and highest degree of the clergy in the Orthodox Church (episkopos in Greek, which means overseer). He is the successor to the Apostles in the service and government of the Church. A bishop is responsible for and the head of all the parishes located in his diocese. All authority of the lower orders of clergy is derived from the bishop. No divine services may be served in any Orthodox temple without the authorization of a bishop.
Episcopal Ministry
Rankings of Bishops
In the degree of their ordination, all bishops are equal. Nevertheless, there are distinctions of administrative rank among bishops.
Patriarchal Vicars
In the Church of Antioch, a bishop who is in charge of a newly-created diocese on behalf of, and under the supervision of, the Patriarch of Antioch is called a Patriarchal Vicar. The diocese is usually kept under the direct control of the patriarch until it becomes self-supporting. Patriarchal Vicars are not members of the Holy Synod. When the diocese becomes self-supporting, it is usually granted a ruling bishop who is a member of the Holy Synod. The equivalent title in the Roman Catholic Church is Vicar Apostolic. They are significantly different from auxilliary bishops.
Diocesan Bishops
Archbishops and Metropolitans
The title of archbishop or metropolitan may be granted to a senior bishop, usually one who is in charge of a large ecclesiastical jurisdiction or archdiocese. He may or may not have suffragan bishops assisting him. In the Slavic and Antiochian traditions, a metropolitan outranks an archbishop. The reverse is true in the Greek tradition. The Antiochian tradition also uses the style of metropolitan archbishop to differentiate from metropolitans in the Greek tradition.
The change in the Greek tradition came about because at one point in history, the diocesan bishops of ancient sees (which in the Greek world are pretty much all of them) all came to be styled as metropolitans. Thus, while in the Slavic and Antiochian traditions, an archbishop is a senior bishop with an honorific title, a metropolitan is a bishop in charge of a major see and thus holding a territorial title. In the Greek tradition, all diocesan bishops (with a few exceptions) are metropolitans by default, and thus an archbishop is one who holds his title by reason of territory.
The title patriarch is reserved for the primate of certain of the autocephalous Orthodox churches. The first hierarch of the other autocephalous churches are styled metropolitan or archbishop (or some combination).
Special Forms
The primate of the Church of Constantinople takes the title Ecumenical Patriarch. The primate of the Church of Alexandria takes the title Pope and Patriarch. The primate of the Church of Georgia takes the title Catholicos-Patriarch.
In general, when referring to a hierarch, His is often used (e.g. His All Holiness, BARTHOLOMEW, Archbishop of Constantinople, New Rome and Ecumenical Patriarch visited Tarpon Springs, Florida in January of 2006). When speaking to a hierarch Your is often used (Your Eminence, I'm so glad to see you!).
Bishop Tikhon (Fitzgerald) of San Francisco and the West (OCA) wrote a short memo on the Conventions of writing to a hierarch.
Bishop's Vestments
See also


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Government Programs
Government programs are mortgages that are insured or backed by the Federal Government. These types of mortgage protect the lender if borrower does not pay their loan. At Homestead we offer many types of government programs to suit all needs.
FHA mortgages are a great option for homebuyers looking for a mortgage program with lower down payment options and flexible qualifying guidelines.
A VA mortgage is a valuable benefit for qualifying military veterans and active servicemen and women. They program offers no down payment options with flexible qualification guidelines.
Energy Efficient Mortgage (EEM)
Include the cost of add energy efficient improvements with an Energy Efficient Mortgage.
FHA 203k Renovation
An FHA 203k mortgage allows buyers to borrow the funds for both the purchase and renovation of a home giving the availability or renovating without the need for a second loan.
FHA 203k Streamline
An FHA 203k Streamline in allows for the purchase or refinance of properties that do not require structural changes and will not exceed a total of $35,000.
FHA Streamline Refinance
Current FHA mortgage holders may benefit from refinancing options available with a FHA Streamline.
VA Streamline Refinance
Current VA mortgage holders may benefit from refinancing options available with a VA Streamline.
A USDA mortgage is a great option for borrowers looking to finance a home in eligible rural areas. It is ideal for those seeking financing with no down payment and liberal qualifying guidelines.


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About Fruit Collection :
If you wish to have a very good containers for home use design, please contact our secretariat and indicate that you wish to work with JL/18496016 for your containers for home use project. We will process your request immediately and forward your requirements to JL/18496016.
Within the scope of Bakeware, Tableware, Drinkware and Cookware Design, our partners have completed projects such as: Table Cruet/Condiment Set, Table Pepper Mill/Shaker, A Kettle, Cutlery Set, Spoon, Gift, Salad Dressing Set, Cake Stand, Cookware Set, Glass Object, Bottle Chiller/Ice Bucket, Modular Buffet, Fruit Tree, Lemon Juicer, Stovetop Kettle, Wooden Spoon, Tea Set, Dish, Grater, Cocktail Plate, Disposable Plate, Plate, Open Tableware System, Knife Holder, Cleaning Wine Accessory, Multifunctional Tableware, Teapot and Teacups, Cruet. Condiment Container, Decanter Dryer, Coasters, Knifeblock, Stemware, Teapot, Nut Cracker, Kids Tableware and Sake Set. For more Bakeware, Tableware, Drinkware and Cookware Design works, check our design portfolio.


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Mozillian Profile
Sirajul Muneer
Vouched By
Midhun Manoj
Siraj has been a passionate soul of Mozilla Kerala since its inception. He has helped the local community evangelizing in numerous events and helped in bringing lots of contributors to the Mozilla family. He is the core team member of the Community initative known as HackrGirls aimed at brininging more women folk to contribute in open source projects. I am happy to vouch for him.


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Thanks to its highly effective extra thick single protection and special fibre optic technology (Crystal Clear Material), this premium cable will convince you with excellent and stable signal transmission.
The information provided on this page is a property of the manufacturer or the brand.
To find out more, please visit: http://www.avinity-cable.com/


text:
Happy New Year!!!
Why, it seems like only yesterday I was celebrating this joyous occasion with my friends and –
What's that? It was over two months ago?
Well. Better late than never, right?
At least the WordPress.com stats helper monkeys weren't late when they prepared a 2011 annual report for this blog, similar to the one they put together last year. Only this year's version comes with lag-inducing graphics.
Those same lag-inducing graphics make it slightly harder to pull into a fully commented blog post. But fear not, for I have
carefully transcribed copy/pasted the text information over here so I can write snarky comments.
If you'd like to see the dazzling webpage in all its glory, just click here to see the complete report.
If you'd prefer the transcription (with my comments, in dark red), then read on!
WordPress.com presents
Me, Myself… And All Of Them
2011 in blogging
There are lag inducing fireworks for each day I wrote a post. I don't know if they loop — I went and read the rest of the report instead. If you have the patience to watch, feel free to let me know. 😀
Happy New Year from WordPress.com! And a very Happy (belated) New Year right back atcha, WordPress.com!
To kick off the new year, we'd like to share with you data on your blog's activity in 2011. You may start scrolling! If I can through the fireworks lag. Does all this lag mean I need a new computer? I think it does.
Crunchy numbers (Om nom nom nom…)
The concert hall at the Sydney Opera House holds 2,700 people. This blog was viewed about 11,000 times in 2011. If it were a concert at Sydney Opera House, it would take about 4 sold-out performances for that many people to see it. That's a pretty solid number there. But doesn't it sound even more impressive when you use last year's comparison? A Boeing 747-400 passenger jet can hold 416 passengers, which means 11,000 people would fill 26.44 jets! Or, if you gathered the lifetime production of saliva from 11,000 people, it would fill about 104 Olympic swimming pools! (Thanks again, Weird Converter!)
In 2011, there were 62 new posts, growing the total archive of this blog to 103 posts. There were 245 pictures uploaded, taking up a total of 246mb. That's about 5 pictures per week. I have a tendency to upload images first,
ask questions put them into posts later.
The busiest day of the year was April 27th with 190 views. The most popular post that day was My Guild Still Doesn't Understand Me.
This section had four images in it. I assume these images were from some of my most popular posts.
The largest image was this one, from the 'most popular post':
Followed by three smaller images also from popular posts.
The first one is related to Xena searchers, as it was when I was introducing Xena the cat, even if her picture wasn't pulled:
The next are people, who like me, were looking for some Thor fanservice:
(Speaking of, I can't wait for The Avengers to come out. I hope it's good!)
And lastly, my perennial popular post contains this most awesome picture:
Someday I'll find out who this Blood person is so I can ask gush about their awesome art!
How did they find you?
The top referring sites in 2011 were:
- twitter.com Thanks for reading, Twitter Friends (and spam bots!)
- daily-quests.com I drew Fyreuni for last year's Secret Santa Art Trade and she posted it on her site. I think some of her readers stopped by to visit. :3
- spiritbond.blogspot.com Thanks for putting me on your blog roll!
- wordpress.com Whoo, wordpress works its magic!
- Google Reader Thanks for reading through the magic of Google Reader (now with new privacy policies)!
Some visitors came searching, mostly for xena, unamused, xena warrior princess, unamused face, and texas hash. I'm getting steady traffic from people looking for these images. In fact, I had a huge traffic spike after Lucy Lawless was arrested… Keep it up, Google Searchers — you boost my ego!
Where did they come from?
Most visitors came from The United States. The United Kingdom & Canada were not far behind.
And here are the detailed stats that I am helpfully writing out instead of making you mouse over, going from largest to smallest person-thing. Unfortunately, they don't provide the overall percentage for each region.
North America
- The United States 82.9%
- Canada 13.2%
- Mexico 2.2%
- Honduras 0.2%
- Puerto Rico 0.2%
- The United Kingdom 23.6%
- Italy 8.3%
- Netherlands 8.2%
- Germany 6.3%
- France 4.7%
- Australia 86.4%
- New Zealand 13.2%
(I guess there are only two places in Oceania that viewed the site. >_>)
South America
- Brazil 65.4%
- Columbia 11.0%
- Argentina 9.6%
- Chile 7.0%
- Peru 1.5%
- Philippines 15.5%
- Indonesia 13.4%
- India 12.5%
- Malaysia 7.8%
- Israel 6.9%
- Egypt 55.6%
- South Africa 29.6%
- Algeria 5.6%
- Sudan 3.7%
- Ghana 1.9%
Whoo! Fun stats, eh?
Who were they?
Your most commented on post in 2011 was The Return of the Link Round Up! Best way to get lots of comments on a post: Link other people and respond to all comments. That way the count doubles! XD
These were your 5 most active commenters:
- 1 TheIdiotSpeaketh 5 comments WoW bloggers may not be familiar with this gentleman, but he writes one of the most hilarious/interesting blogs in the world! I encourage you to check it out!
- 2 Faeldray 5 comments Writer of Petoholics Anonymous, she is filled with much awesomeness.
- 3 Cynwise 3 comments If you don't know who Cynwise is, I… I don't know what to say. Besides telling you to follow
herhim on twitter and read all his blogs immediately!
- 4 Jasyla 3 comments Jasyla cannot be tamed! No really, that's her blog. Go check it out. :3
- 5 kamaliaetalia 2 comments She's a Shaman, just like me! Go read her blog too!
Perhaps you could follow their blog or send them a thank you note? Or I'll just thank them here. So thank you all for commenting. And YOU all should check out their blogs, posthaste! They all are super awesome!
Attractions in 2011
These are the posts that got the most views in 2011. You can see all of the year's most-viewed posts in your Site Stats.
- 1 My Guild Still Doesn't Understand Me 2 comments April 2011 Thank you google image search, for the many views!
- 2 Kitty! 7 comments July 2011 Cute kitties named Xena always pull in the high views. *eyebrow waggle*
- 3 Thoughts on Thor 2 comments May 2011 Sexy men always pull in the high views. *eyebrow waggle*
- 4 A Picture Tells A Thousand Words (A Shared Topic Post) 6 comments July 2010 Awesome art always… okay, you get the picture.
- 5 Texas Hash – Not What You Think It Is 1 comment April 2011 I think the title of this post speaks for itself.
Some of your most popular posts were written before 2011. Your writing has staying power! Consider writing about those topics again. What was that WordPress? You think I should put in more google image search pictures to attract more google image searchers? CAN DO.
The main report page goes on for a little while longer, but it's mostly WordPress telling you to keep blogging and the like. All in all, it wasn't a bad year. Hopefully this year will be just as good, if not better. After all, I'm off to a great start…


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A Wild 24th
It was my birthday a few weeks ago and to celebrate I decided what better way than with Zoo Lates at London Zoo!
I am obsessed with animals (especially Lions and Penguins) and felt that I just couldn't pass up this opportunity.
The zoo was filled with exciting things to see and do, we started with the animals, in particular the Africa area. We spent probably far too long laughing at an Okapi's tongue, watched a graceful giraffe, braved the nocturnal section, searched for the illusive sumatran tiger, partied with the penguins, longed after lions and much more!
My favourites, of course, were the Lions and Penguins. The Lions we're so close to the glass I could've touched them! The penguins unfortunately stayed towards the back of their enclosure, but then again it was right before they closed so maybe they were all tired. I pulled a penguin pose for the camera and then tried to steal one of the cardboard cut outs…Or at least thought about stealing it…
They also had lots of bars, all with a different theme such as the playroom where you could have a wrestling match, hula hoop, play jenga and even twister! There was a silent disco where everyone wears headphones which the music is played through, hilarious to listen too when you take them off and hear everyone singing out of tune. There was also a big international food market with lots of tasty delights to sample.
I wore a bright, high waisted, tribal skirt to to give off an African feel and matched it with a bright orange crop top and sandals. I felt quite…naked. I'm not used to going out in such little clothing, but it was really warm and so i didn't regret it.
I even painted my nails to match with the animal theme!
The whole event was very well run. There were loads of things to do, not just seeing the animals, the staff were extremely helpful and the atmosphere was electric! The animals started going to bed (or so we were told) at 8:30 and gradually the enclosures were closed off until everyone was in the 'entertainments' area for the last half hour.
Afterwards we carried on the party in Camden, always a fun place to go.
The day after was my actual birthday. I decided what better way to celebrate and recover from the night before than by having a bbq! We borrowed a friends garden and bbq and then had a nice, relaxed afternoon chilling in the sun (if you ignore the random downpour that stopped as suddenly as it started!)
For the bbq I decided to dress up a bit still and wore one of my favourite dresses. I bought it at a festival and have always loved the way it poofs out in the skirt. The fabric is also really pretty, I fell in love with it at first sight!
I kept myself warm with a cute, batwing cardigan from warehouse.
Super comfy!
I made these earrings ages ago and found they matched perfectly! I really like the little red and blue beads and was experimenting with using suade, i think they turned out really nice.
The bag is from Zatchels and was a suprise birthday gift from my sister! Zatchels are all handmade and just exquisite. I absolutely love it and it even has a little space for one of my business cards to be on display! They come in a wide range of colours and patterns too.
It was a really great birthday! Hopefully next years will be just as good!


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This was published July 6, 2013.
MONTREAL - The train that careened into the centre of town in Lac Mégantic early Saturday morning was unmanned when it derailed and exploded in a huge ball of flame, says a spokesperson for the company that owned the locomotive.
Joseph R. McGonigle confirmed to The Gazette early Saturday afternoon that shortly before midnight, the train's conductor stopped in nearby Nantes, locked the brakes and checked to ensure that the rail cars carrying thousands of litres of crude oil were all securely attached.
He then checked into a nearby Lac Mégantic hotel for the night. Another conductor was reportedly expected to take over driving the train within a few hours.
"Sometime after (the first conductor left), the train got loose," said McGonigle, who is vice president of marketing for The Montreal, Maine & Atlantic Railway. "It travelled under its own inertia to the centre of the town."
The locomotive portion of the 73-car train actually detached half a mile outside of the small town, he added, but the cars carrying the oil kept right on rolling. McGonigle said there are security mechanisms in place to prevent anyone from tampering with the train, and the proper checks were done by the conductor before he left the vehicle. No one except him or another employee of the company should have been able to set it in motion.
"That's what confuses us. How did this happen?" McGonigle said. "There are many fail-safe modes. How this happened is just beyond us."
He added that nothing like this has ever occurred before with one of the company's trains.
The Montreal, Maine & Atlantic Railway was founded in January of 2003. According to the company's website, it owns over 510 route miles of track, serving customers in Quebec, Maine, Vermont and New Brunswick.
McGonigle said the company is assisting authorities and will continue to cooperate with the investigation into the accident.
Twelve hours after the derailment set off a series of explosions, firefighters still could not get near the centre of the fire raging in the downtown area of historic Lac Mégantic, authorities told media.
About 1,000 people were evacuated during the night from the centre of the picturesque town to a local high school where the Red Cross had set up emergency services. There were no reports of deaths or injuries, police said.
"We're told some people are missing, but they may just be out of town or on vacation," Lt. Michel Brunet of the Sûreté du Québec said at an 8 a.m. news conference. "We're checking all that, so I can't tell you at the moment whether there are any victims or people who are injured."
A Facebook page has been set up to help people find missing friends or relatives.
Please click the image below to go to the Facebook support group. For mobile users, please follow the link at the end of the story.
Mayor Colette Roy-LaRoche was on the verge of tears Saturday morning as she spoke to media.
"When you see the downtown of your city almost destroyed, you think, 'How are we going to get through this? But I can assure everyone here that all the authorities and ministries have been very supportive. We have deployed all the resources possible."
An estimated 120 firefighters arrived throughout the night and morning from nearby Sherbrooke and Saint-Georges-de-Beauce and farther away from the United States.
The Environment Department announced concerns with an oil spill on the lake and river, advising towns in the area to be careful about taking water from the Chaudière River.
There were also reports Saturday morning that flames had been seen in Lac Mégantic's aqueducts. Town residents, who number just under 6,000, were told by authorities to be sparing in their consumption of drinking water.
Fire and police officials have established a 1-km safety perimeter around the fire and have ordered people to stay out of the downtown area, saying firefighters and other emergency workers could not cope with people who want to have a look at the disaster. Boats were also forbidden on the east shore of Lac Mégantic, between the Parc des Vétérans and the Parc de OTJ.
A team of at least six investigators is already on its way to the site of the train derailment, Transportation Safety Board of Canada spokesperson Chris Krepsky said Saturday.
Even though the investigators, who are traveling from Montreal, Ottawa and Darmouth, will not be able to get near the site of the accident, they will start gathering information from witnesses and company officials as soon as they arrive in Lac Mégantic, said Krepsky. He said it was too early to say if there are similarities with other train derailments.
Around 2 p.m., when winds changed direction sending flames toward the parish of Notre-Dame-de-Fatima, authorities ordered the evacuation of residents in that area.
The SQ is asking anyone who believes someone is missing to notify the police by calling 1-819-583-2441.
With files from The Canadian Press
email@example.com and firstname.lastname@example.com
Twitter: monique_muise and sparksriley


text:
Arts & Entertainment
Optic-Herald 2008 coloring contest
- Details
- Category: Arts & Entertainment
- Published on 25 December 2008
- Written by Mount Vernon Optic-Herald
Karlee Jo Fielden, age eight was the second place winner of the Optic-Herald Coloring Contest.
She received $10 in cash prize. See the Dec. 25 edition of the Mount Vernon Optic-Herald for the details.


text:
Coloring Pages
Printable Coloring Pages
Online coloring Activities
Work Sheets
Practice Worksheets
How to draw
Coloring books
Preschool Coloring Pages
Animals Coloring Pages
Cartoons Coloring Pages
Animated characters Coloring Pages
Fantasy and medieval Coloring Pages
Holiday Coloring Pages
Religious Thme Coloring Pages
Nature Coloring Pages
Human Coloring Pages
Food Coloring Pages
Music Coloring Pages
Home appliances Coloring Pages
Vehicles Coloring Pages
Sports Coloring Pages
Regional and Cultural Coloring Pages
Capital Cursive Letters Z Worksheet
Print Capital Cursive Letters Z Work Sheet (B/W)
Generally, there are four types of letters for writing English among them to two types each in two part, are most common in use. They are capital, small, cursive-capital and small-capital. In this book we are presenting cursive capitals with pictures and
First Sheet
Last Sheet
Tips for printing worksheets:
Step 1: Click on "Print" link of your choice, if you want a Capital Cursive Letters Zwork sheet then you need to click on "Print Capital Cursive Letters Z Work Sheet (B/W)" link. If you want colored (already filled with colors) Capital Cursive Letters Z work sheet to print then click "Print Capital Cursive Letters Z Work Sheet (Color)".
Step 2: Now a new pop-up window will open along the Capital Cursive Letters Z image of your choice (if new window does not open-up then you may need to check your pop-up blocker settings.). Now click on "PRINT". This will open printer dialog, select your print and print.
Print Capital Cursive Letters ZWork Sheet (B/W)
Printable coloring pages
Free Printable Cards
Online coloring activities
How to draw
Work Sheets
Practice Worksheets and Activities
Coloring books
Rhyming books
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Dear all,
After a successful launch of the first edition of the Pathfinder, an online journal of Peace and Conflict Studies, I am happy to announce that we are getting ready for the second edition (scheduled to go online in January 2010). The Pathfinder is geared towards furthering the understanding of conflict and proposes innovative approaches to building peace by means of a multi-disciplinary approach that explores issues such as identity, gender, race, ethnicity, religion, culture, human rights, non-violence, social change, social justice, social movements, human and environmental security, sustainable development, governance and democracy.
I encourage you to start thinking possible topics and papers (including your class papers) that might fit the broad scope of The Pathfinder. An official call for papers will go out sometime towards the end of this semester with the deadline for submissions scheduled for tbe beginning of the Fall semester.
For those who have not yet had a chance to take a look at the current edition of the Pathfinder, the URL is: thepathfinderjournal.com
Julia Steger, a third semester student of conflict resolution and migration studies will assist me as the student editor for the second edition.
Do get in touch if you have any questions,
Pushpa Iyer
Assistant Professor – Conflict Resolution Graduate School for International Policy Studies Monterey Institute for International Studies 460 Pierce Street, Monterey, CA 93940
Contact: 831-647-7104, firstname.lastname@example.com thepathfinderjournal.com


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Sorry Old Man
I just realized how much yellow I used… It's a good thing the yellow skein is almost done! These are only a few of the ones I finished, I have a few that weren't worthy of being included.
I'm awaiting a yarn delivery from Jimmy Beans Wool. I received a partial shipment today so when I get the rest of it I'll reveal my super secret plans. So far their customer service has been fantastic and shipping super super fast. It was my first online yarn purchase and I have a feeling they'll be my go-to site. My receipt had a happy face (I'm an avid supporter of smiley faces in emails and notes) and they included candy! Granted it was root beer flavored and I hate it, but it's the thought that counts!
I also received these lovely vintage heeled sandals from etsy seller Sugar Lily. Lightning fast shipping and a lovely handwritten thank you note!
My usual Starbucks run was interesting today. My arm was stretched out and nearly touching the door handle when a man said, "Here, I got it." By the time he finished saying that I had already opened the door so I said "Thanks anyway!" He followed me in and in an irritated voice said something along the lines of, "I said I was going to get it."
Sorry old man, you just weren't fast enough! 😉
I'm going to start the weekend off by watching Eat Pray Love with two of my besties, I hope you all enjoy yours!


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Eliminating unexpected surprises
You will need to be well informed with regards to Bathroom Renovation in Conway, WA. You shouldn't go in without understanding it, and you want to learn what you should expect. We take the surprises from the equation by giving accurate and thorough advice. You can start by going over your job with our customer support associates when you dial 888-341-7776. We will address all of your questions and concerns and set up the preliminary meeting. We will work together with you through the entire project, and our staff can appear promptly and ready.
Pick Bathroom Renovation Guys for Bathroom Renovation in Conway, Wyoming
When you're arranging a project regarding Bathroom Renovation in Conway, WA, there are lots of reasons to work with Bathroom Renovation Guys. Our equipment are of the highest quality, our money saving techniques are realistic and effective, and our client satisfaction scores are unsurpassed. We will be ready to assist you with the most expertise and experience in the market. Call 888-341-7776 when you need Bathroom Renovations in Conway, and we'll work closely with you to systematically complete your job.


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A Guide to the Round Rock Depot Records, 1881-1928
Biographical Note
In 1876, the first railroad was introduced in Round Rock, Texas, resulting in the relocation of the town's primary business district. This event rose from the incorporation of the International and Great Northern Railway Company (I. & G. N.), which intended to construct railway access across Texas. In 1876, the I. & G. N. offered daily service between Round Rock and Georgetown; however, during the 20th century the depot was used less as railway use dropped throughout the state and the entire country. Presently, Amtrak and the Georgetown railroads use the I. & G. N. rail lines, although they do not make stops in Round Rock.
"The Railroads of Round Rock." Round Rock Texas. Accessed August 30, 2011. http://www.roundrocktexas.gov/home/index.asp?page=1767.
Scope and Contents
Letterpresses, business documents, and a ledger comprise the Round Rock Depot Records, 1881-1928, relating to the operation of the Round Rock Railroad Depot. Letterpresses hold the financial statements of the I. & G. N. Railway Company for the years 1916-1928. Business records include receipts, notices, a rate schedule, and freight waybills for I. & G. N. and the Missouri Pacific Railway Company involving transactions with several companies, including Round Rock White Lime Co., Round Rock Broom Co., and Alexander Grocery store. A ledger contains financial transactions (1884-1885) for the Missouri Pacific Railway Company.
Access Restrictions
This collection is open for research use.
Administrative Information
Preferred Citation
Round Rock Depot Records, 1881-1928, Dolph Briscoe Center for American History, The University of Texas at Austin.
Processing Information
Basic processing and cataloging of this collection was supported with funds from the National Historical Publications and Records Commission (NHPRC) for the Briscoe Center's "History Revealed: Bringing Collections to Light project," 2009-2011.
Detailed Description of the Papers


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- Yield
- Makes 12 hors d'oeuvre servings
- Active Time
- 30 min
- Total Time
- 40 min
- 12 large eggs
- 1/2 cup mayonnaise
- 2 teaspoons brown or yellow mustard
- 1/4 cup finely chopped sweet pickles
- 1/4 cup finely chopped celery
- Garnish: finely chopped pimiento-stuffed olives; paprika
- Cover eggs with cold water by 1 1/2 inches in a 4- to 5-quart pot and bring to a rolling boil, partially covered with lid. Reduce heat to low and cook eggs, covered completely, 30 seconds. Remove pot from heat and let eggs stand in hot water, covered with lid, 15 minutes. Rinse eggs under cold water 5 minutes to stop cooking.
- Peel eggs and halve lengthwise. Carefully remove yolks and mash in a bowl with a fork. Add mayonnaise, mustard, pickles, celery, and salt and pepper to taste to yolks and stir with fork until combined well, then spoon into egg whites.
Cooks' note:
Deviled eggs can be assembled (but not garnished) 2 hours ahead and chilled, covered.


text: Quick View Compare Picnic Pattern Background Stamp SKU: SS-0436 $14.95 Create a fun picnic or beach theme card or use it as a trendy plaid background. Contains 1 stamp. Measures approximately 4 1/4" x 5 1/2". Made in the USA of high quality deeply etched red rubber with cling mount. Our stamps create one of the best... Add to Cart


text:
Contributed byLeland S. Pierson IIIDept. of Plant Pathology, University of Arizona, Tucson, AZ 85721.Carol A. IshimaruDept. of Bioagricultural Sciences and Pest Mgmt., Colorado State University, Fort Collins, CO 80523.
Pierson III, L.S. and Ishimaru, C.A. 2000. Genomics of Plant-Associated Bacteria: A Glimpse of the Future That Has Become Reality. APSnet Features. Online. doi: 10.1094/APSnetFeature-2000-0900
The largest amount of biochemical and genetic diversity on Earth exists within the prokaryotic domains Archaea and Bacteria. Members of these domains are found in every conceivable (and sometimes inconceivable) environmental niche based on their ability to utilize diverse energy sources, electron donors and acceptors (8). Because higher organisms on Earth evolved in the presence of prokaryotes, they are intimately associated with every organism. Prokaryotes are responsible also for most of the major steps of biogeochemical cycles without which plant, animal and human life would be impossible.
A subclass of prokaryotes of direct interest to plant pathologists includes those bacteria that interact intimately with plant hosts and directly affect overall plant health and survival. Some prokaryotes serve to improve plant health while others negatively impact plant health, ranging from slightly deleterious effects to partial or complete death of the plant. The development of the technology to sequence large stretches of DNA (genomics) and to analyze this DNA (bioinformatics) is beginning to have enormous impacts not only on the way scientists carry out research but also in the way we think about the overall biology of plant-microbe interactions.
It can be argued that the field of genomics actually began several years ago in virology, where the ability to determine the DNA (or RNA) sequence of a virus allowed comparisons of genomes, enzyme activities, and many other aspects previously difficult or impossible to perform (7). The net effect of the development of viral genomics was the revolution of plant virology and the resultant explosion in our understanding of plant-viral interactions.
In an analogous manner, the emergence of microbial genomics will enable us to answer classical questions about plant-associated microbes that once seemed, at least to some of us, as unobtainable as intergalactic space travel. In the pre-genomics era, we probed the microbial universe one factor at a time, adding incrementally to our knowledge of one or a few bacteria. As we enter the age of high throughput sequencing, or what is referred to as "the age of genomics," scientists can begin to use a holistic approach for answering questions of consequence to plant health. Some of the many exciting questions are:
Fig.1. Click image for an enlargement and more information.
As recently as 1995 The Institute for Genomic Research (now part of the J. Craig Venter Institute) published the first complete sequence of a bacterial genome. Since then the number of completed bacterial genomes has risen to 24. Several others are expected to be completed within the next 2 years (See Genomes OnLine Database). Most of the genome sequencing efforts so far have targeted medically or industrially important microbes and relatively few target plant-associated bacteria. Fortunately, genome sequencing efforts in Brazil, France and the United States increasingly focus on plant pathogenic bacteria. In their very recent article, a team of Brazilian scientists from São Paulo present the first complete genome sequence of a phytopathogen. Simpson et al., (10) sequenced the entire genome of a strain of Xylella fastidiosa, and will soon finish sequencing another plant pathogen, Xanthomonas axonopodis pv. citri. In 2000, the United States Department of Agriculture (USDA) launched the first US public initiative for complete genome sequencing of agriculturally related microbes, including plant-associated bacteria (IFAFS). Together with private ventures in the US, France and elsewhere, the amount of genomic information on plant-associated bacteria is increasing exponentially.
The age of microbial genomics and its implications for plant health will be highlighted at the upcoming 2000 Annual Meeting of the American Phytopathological Society (August 12-16, 2000, New Orleans) in a symposium entitled "Genomics of Plant-Associated Bacteria". The APS Bacteriology Committee is sponsoring the symposium. Co-organizers for the symposium are Leland S. Pierson III, University of Arizona, and Carol A. Ishimaru, Colorado State University. An international group of speakers will present the current status and future goals of several essential microbial genome sequencing projects. The symposium will be held Tuesday, August 15, 2000 from 1:00 to 5:00 PM. The symposium is supported by funds provided by the APS Council, the College of Agriculture and Life Science at the University of Arizona, and the Colorado Agricultural Research Station and College of Agricultural Sciences at Colorado State University. Funds for the Symposium are provided also through a work agreement between the Animal and Plant Health Inspection Service (APHIS)/USDA and the APS Bacteriology Committee, which resulted in a summary of plant pathogenic bacteria prevalent in the U.S.
The genomes of plant-associated bacteria contain DNA, which is made up of the four nucleic acid bases, adenine (A), guanine (G), thymine (T) and cytosine (C). It is the specific number and order of these bases that uniquely identifies an organism. Bacterial genomes consist of large DNA molecules arranged in one or more circular or linear chromosomes. In addition to chromosomes, bacterial genomes often contain extra chromosomal DNA molecules, called plasmids, which may vary in length from a few kilobases (kb) to over 400 kb. Estimated genome sizes of plant pathogenic bacteria vary among species. Some of the smaller genomes are estimated to be in the range of 2.5 million (mega) base pairs (Mbp) and the larger ones are probably greater than 5 Mbp.
The goal of genome sequencing is the production of a map that identifies the linear arrangement of all bases in an organism's DNA. Obtaining such a map is not a trivial undertaking; however, technical advances in sequencing and data processing continue to reduce the time and expenses involved. The complete sequencing of a 2.5-Mbp genome presently can take less than six months at a cost of less than $500,000.
Obtaining the complete sequence of an organism usually involves multiple sequencing strategies. A common approach is to use a combination of shotgun-sequencing, in which small fragments of the DNA are cloned and sequenced, followed by a gap-closure phase (10). In the latter, larger DNA fragments contained in cosmid or BAC libraries are sequenced. When finished, the complete sequence gives the exact size and structure of the genome, including the number and form of chromosomes and plasmids.
To make biological sense out of all the As, Ts, Gs, and Cs, sequence data must be "mined" or analyzed by software specifically developed to identify possible open reading frames (ORFs). While ORFs are associated with sequences that are transcribed and translated into proteins, other sequences give information about gene expression. The term bioinformatics describes the mining of biological sequence information to predict gene function, protein and RNA structure, gene regulation, genome organization and phylogenetic history of genes and gene families. During this process (Fig. 3), a test sequence is compared to all the sequence information deposited in worldwide gene banks. Database searches provide a probability score that one sequence is similar to another. If highly significant, these similarities may infer homology (relatedness through evolution) or function (9). The result of all this data mining is an annotated map of the genome.
Fig. 3. Click image for larger view.
Recent software developments enable analysis of the extremely large data sets generated by complete genome sequencing and provide for comparisons at the whole genome level. As an example, the program MUMmer (Maximal Unique Match) aligns segments of closely related DNA sequence several million base pairs in length (3). This level of data mining or "comparative genomics" has direct and exciting implications for plant pathology. As the number of complete genome sequences increases, comparisons across genera, species, subspecies, pathovars, and strains will become possible.
Through genomics, we can begin to address questions about the evolution of plant-associated bacteria. By comparing the arrangement of DNA along entire genomes, we can begin to propose models of how genetic information passed between organisms. Envision the magnitude of this new perspective as the difference between looking at the earth from your back porch and looking at it from a space shuttle. All inversions, rearrangements, and insertions in an organism's genome would be viewable, giving rise to all sorts of questions: What does the arrangement of genes in a pathogen tell us about evolution of host specificity or pathogenicity? Which sequences indicate gene transfer between related or unrelated organisms? The range of exciting research questions being limited only by the imagination.
The complete genome sequence gives the exact proportion and distribution of each of the four bases in the genome. The relative amount of each base, reported as the G+C content, is characteristic of a genus. Based on prior measurements, the genera of certain plant pathogenic bacteria, such as Erwinia, are predicted to have moderate G+C contents, while others, such as Clavibacter and Pseudomonas, are predicted to have much larger G+C contents (upwards of 70%). Localized variations in the G+C content along the genome have significant implications for understanding the potential routes of genetic exchange between organisms. For example, by using genetic tools such as transposon mutagenesis and gene complementation, plant bacteriologists have located and sequenced large segments of DNA associated with pathogenicity. The G+C contents of some of these pathogenicity-related regions are distinct from the overall G+C content of the organism. From this and other information, scientists postulate that the presence of "pathogenicity islands" can indicate how some bacteria may have evolved to become pathogens (2,5,6) (Fig. 4).
Fig. 4. Hypersensitive response (HR) in tobacco caused by cells of Erwinia amylovora (right) and Clavibacter michiganensis (left). Genes required for HR production and pathogenicity are clustered in the genomes of Gram-negative bacteria, such as E. amylovora (Click image for larger view).
With a major emphasis on large-scale sequencing of plant-associated bacteria will come knowledge of the functional relationships between bacteria, especially those with different pathogenic life styles. Perhaps we will find evidence that genomes of bacteria from similar habitats contain similar sets of genes required for survival in that habitat. Perhaps we'll identify regions that are distinctive of life as an epiphytic or life as an endophyte.
Surely, the era of genomics will usher in significant advances in our understanding of plant-microbe interactions. A few of the many possible breakthroughs will be in:
The World Wide Web affords immediate access to all the available information contained in an organism's DNA. This access results in near real-time feedback and analysis by the entire scientific community. As Dr. Stanley Falkow eloquently said recently, "[Genomics] reminds me of the 'good old days' of bacterial conjugation when each day's experiments revealed some new facet of genes and biology.... There was just too much to discover to worry about competition" (4). Genomics challenges our academic institutions to provide new graduate education experiences that can advance the use of these strategies and develop new partnerships between disciplines. Already disciplinary lines are becoming blurred and discipline insularity is becoming less prevalent.
Once the complete genome sequence of an organism is known and annotated, the next challenge is identifying gene functions of all possible ORFs. Plant pathologists will provide the human intelligence needed to analyze and rank the importance of the ORFs for their possible biological significance. Bioinformatics approaches will identify functions of a portion, but not all, of the ORFs in a genome, and some of the assigned functions may actually be incorrect. In Escherichia coli, the common intestinal bacterium now studied intensively for over forty years, the functions of one-third of its 4,288 ORFs (ca. 1,415) are still unknown (11). Thus, gene disruption and replacement experiments will continue to play a critical role in functional analyses of predicted ORFs. Still, the shear volume of sequence data generated by genome projects demands improvements be made in technologies for functional analysis. One such technology is DNA microarrays, which have quickly become the method of choice for examining gene expression on a genomic scale (for related article, see Nature Genetics, Supplement, volume 12, 1999).
With the development of microbial genomics comes a responsibility to plant pathologists of making the most of these powerful resources. We must begin applying this information for reducing threats and losses from plant pathogenic bacteria and for improving the viable use of beneficial bacteria. There are very few means of controlling plant pathogenic bacteria. The limited number of chemicals and sources of disease resistance means the best strategy is still prevention through exclusion. Plant virologists have already utilized their knowledge of complete plant viral genomes to develop transgenic virus-resistant plants. Will we be able to do the same with bacterial genomics? Perhaps other methods of disease control will develop in a manner analogous to pharmaceutical approaches for veterinary and clinical medicine. Knowing the complete genome sequences of many plant-associated bacteria may allow us to identify the Achilles' heel of a plant pathogenic bacterium or alternatively to convert a potential silver bullet to a golden one.
The APS Symposium on "Genomics of Plant-associated Bacteria" will feature an international assembly of experts in microbial genomics working on a wide-range of plant-associated bacteria. They include:
Noel Keen (Dept. of Plant Pathology, University of California, Riverside, Riverside, California, 92521). Dr. Keen's research has focused on the molecular biology of plant-pathogen interactions, with emphasis on high and low molecular weight signal molecules. Plant disease resistance mechanisms are governed by single Mendelian genes called disease resistance genes. They are involved in the recognition of pathogen produced metabolites, called elicitors, to activate plant defense mechanisms. Dr. Keen's laboratory is involved in the isolation and characterization of several of these elicitors, which are somewhat analogous to antigens in vertebrates. Dr. Keen is involved currently in the sequencing of the genome of the plant pathogen Erwinia chrysanthemi. E. chrysanthemi is a necrotrophic plant pathogen that produces pectolytic enzymes that cause severe soft-rot disease in a wide number of plant hosts.
Andrew Simpson (Ludwig Institute for Cancer Research, São Paulo Branch, Sao Paulo, Brazil). Dr. Simpson is involved in determining the sequence of the genome of Xyella fastidiosa, best known as the causative agent of Pierce's disease on grapevines. However, X. fastidiosa is also responsible for the devastating disease Citrus Variegated Chlorosis (CVC). CVC was first identified in São Paulo and Minas Gerais States in 1987 and was shown to affect all commercial sweet orange varieties. The disease spread rapidly by the use of infected budwood for graft propagation and by sharpshooter insect vectors. It is now widely distributed in all citrus growing regions of Brazil. CVC is now a major concern to the Brazilian citrus industry and is considered to be potentially an industry devastating citrus disease. CVC has been found only in Brazil and Argentina. Disease symptoms include mottled and interveinal chlorosis similar to that seen associated with zinc deficiency, reduced leaf size, and fruit that are small, early maturing, and have a very hard rind which can damage juicing machines. Young leaves do not show symptoms. As the leaves mature, small light brown gummy lesions appear on the under side of the leaves which correspond to the yellow chlorotic areas on the leaf upper side. The lesions on the under side of the leaves may become dark brown or even necrotic. For more imformation, see the X. fastidiosa Web site.
Fernando de Castro Reinach (Instituto de Química, Departamento de Bioquímica (USP), Av. Prof. Lineu Prestes, 748 Cidade Universitária 05508-900 São Paulo, SP).
In Brazil and around the world, Xanthomonas axonopodis pv. citri causes citrus canker in citrus plants with an annual economic impact estimated at tens of millions (Fig. 5). Many other related Xanthomonas species attack other economically important crops such as rice, cotton, beans, and grapes. Knowledge of the complete sequence of the X. axonopodis pv. citri genome will therefore be of enormous potential value to both the Brazilian internal economy and numerous agricultural sectors in a large number of countries worldwide. The genome database generated by this project will be an important resource in efforts to understand Xanthomonas biology in general and the variety of Xanthomonas-host interactions of economic consequence. Furthermore, this genome sequence will be of tremendous use in basic research into the molecular basis of plant-pathogen interactions since the closely related X. campestris pv. campestris is currently being used as a model pathogen in studies with Arabidopsis thaliana. Arabidopsis, whose genome will be completed shortly, is the model organism for studies of plant genetics. Finally, X. axonopodis is a close relative of Xylella fastidiosa, but has a genome of approximately twice the size. (It is estimated that the genome of X. axonopodis pv. citri has approximately 5 Mbp.) The availability of the two genomes will allow us to compare the genetic makeup of these two species and gain insight into the important similarities and differences which determine their unique metabolisms, life cycles and interactions with their common host. For more information see the Xanthomonas citri Genome Project Website.
Christian Boucher (Institut National de la Recherche Agronomique, Centre de Recherche de Toulouse, Biologie Moléculaire des Relations Plantes-Microorganismes, CHEMIN DE BORDE-ROUGE B.P.27, 31326 Auzeville - Castanet-Tolosan, France).Ralstonia solanacearum is a Gram negative beta-proteobacterium. This plant pathogen has an unusually wide host range since it causes "bacterial wilt" disease in over 200 plant species belonging to more than 40 botanical families. Strain GMI1000 causes disease on various solanaceous crops, including potato, tomato and eggplant, and on the model plant Arabidopsis thaliana; it also induces a hypersensitive response after inoculation on tobacco. Professor Boucher is a leading authority on the molecular biology of R. solancearum. In collaboration with Genoscope, Boucher and colleagues are obtaining the complete genome sequence of GMI1000 (Plant-Microorganism Interactions).
Eugene Nester (Dept. Microbiology, University of Washington, Seattle, WA 98195-7242).Dr. Nester's laboratory has been a leader in the molecular analysis of plant-bacterial interactions using the Agrobacterium tumefaciens crown gall-plant tumor system as a model. The soil microorganism, A. tumefaciens, transfers a small piece (T-DNA) of a tumor-inducing (Ti) plasmid out of the bacterium and into plant cells, where it becomes integrated into the plant chromosome and confers new properties on the tissue (Figs. 6A-6D). Agrobacterium is currently being used worldwide to genetically engineer plants. Dr. Nester's laboratory is attempting to understand the mechanisms by which Agrobacterium interacts with plant cells at various levels. Studies in his laboratory have shown that one of the first stages in the bacterial-plant interaction involves the activation of bacterial genes by signals from the wounded plant. These virulence genes, called vir genes, are essential for the processing and transfer of the T-DNA across the bacterial cell wall and into the nucleus of the plant cell. A major focus of his laboratory is to elucidate how Agrobacterium recognizes and processes these plant signals to activate the vir genes. Other studies involve a genetic-biochemical analysis of the vir genes to determine their function in the transfer of T-DNA into plant cells. Dr. Nester's laboratory is responsible for annotation of the Agrobacterium DNA sequence and pursuing the relationship between the sequence and the biology of the organism.
Fig. 6. Crown gall disease caused by Agrobacterium tumefaciens.Model of infection (A) showing bacterial attachment to plant cell (B and C) and formation of galls following transfer of T-DNA into plant (D) (Click on images for larger views).
Carol A. Ishimaru (Dept. of Bioagricultural Sciences and Pest Management, Colorado State University, Fort Collins, CO. 80523-1177).The Gram-positive bacterium Clavibacter michiganensis subsp. sepedonicus (Cms) is the causal agent of ring rot of potato, and it is a significant concern to the national and international potato industries. Almost nothing, however, is known about the specific gene(s) in the bacterium that enable it to cause disease (Figs. 7-9). This is in large part due to the lack of standard tools for genetic analysis, such as transposon mutagenesis, for studying Cms or any of the other plant pathogenic coryneform bacteria. Dr. Ishimaru and her colleagues Drs. Dennis L. Knudson and Susan E.Brown, Department of Bioagricultural Sciences and Pest Management, Colorado State University, have initiated a genome analysis of C. michiganensis subsp. sepedonicus as a means of identifying sequences that may be associated with virulence or pathogenicity in Clavibacter. Their strategy to accomplish this objective capitalizes on the gene similarities seen among other more well-characterized animal and plant pathogens. By constructing a sequence-anchored physical map they are providing an immediate picture of where specific genes are located and arranged in the Cms genome. Dr. Ishimaru specializes in the plant-microbe interactions that occur between C. michiganensis subsp. sepedonicus and potato. Drs. Brown and Knudson bring extensive experience in genomics and bioinformatics of mosquitoes and plants to the collaboration (see the Mosquito Genomics Server).
Fig. 7-9. Coryneform (club-shaped) cells of Clavibacter (left). Leaf (middle) and tuber (right) symptoms of bacterial ring rot (Click on images for larger views).
Delphine Capela (for Jacques Batut) MELILO, a European consortium which includes the Laboratoire de Biologie Moléculaire des Relations Plantes Microorganismes (LBMRPM). Centre National de la Recherche Scientifigue (CNRS)-Institut National de la Recherche Agronomique (INRA) BP 27, 31326 Castanet-Tolosan Cedex, France). Sinorhizobium meliloti (formerly Rhizobium meliloti) forms nodules on the roots of alfalfa as part of a symbiotic relationship with the plant (Figs. 10 and 11). S. meliloti has been a model bacterium for studies on the developmental mechanisms involved in nodule formation. A European consortium led by Prof. F. Galibert and sponsored by the European Union took charge of sequencing the chromosome of S. meliloti strain 1021. Prof. S. R. Long at Stanford University (USA) is responsible for the pSymA project. Sequence of pSymB will be a joint endeavor of Prof. A. Puhler at the University of Bielelfeld (Germany) and Prof. T. Finan and Prof. B. Golding both at Mac Master University (Hamilton, Canada).
The genome of S. meliloti strain 1021 consists of three replicons:
Figs. 10 and 11. Genome organization in S. meliloti (left, click on image for larger view) and nodules caused by S. meliloti on alfalfa roots (right).
Nicole Perna (for Frederick Blattner) (Laboratory of Genetics, University of Wisconsin-Madison, 445 Henry Mall, Madison, WI 53706).
Dr. Blattner's group recently completed the E. coli K-12 genome sequence, and continues to work on the analysis of that organism (Fig. 12). Special interests include the analysis of gene organization, expression, regulation, and functional characterization. The E. coli sequence serves as a baseline for comparative studies of the genomes of pathogenic enterobacteria, and microbial genome organization in general. Currently the laboratory is working on the Bacterial Pathogen Genome Initiative, genome sequencing and comparative genomics. The "Complete Dissection of the Escherichia coli Genome," including global gene expression studies, and the "Natural Variation in O157:H7" are two other projects that the laboratory is currently working on. The laboratory's expertise will allow an overview of genomic analysis in the 21stcentury. In collaboration with Blattner and several plant pathologists, Dr. Perna is investigating the comparative genomics of animal and plant pathogens in the Enterobacteriaceae. For more information, see The UW-Madison E. Coli Genome Project.
1. Alfano, J. R., A. O. Charkowski, W. -L. Deng, J. L. Badel, T. Petnicki-Ocwieja, K. van Dijk, and A. Collmer. 2000. The Pseudomonas syringae Hrp pathogenicity island has a tripartite mosaic structure composed of a cluster of type III secretion genes bounded by exchangeable effector and conserved effector loci that contribute to parasitic fitness and pathogenicity in plants. Proc. Natl. Acad. Sci. USA. 97:4856-4861.
2. Blattner, F. R., Plunkett III, G., Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., and Shao, Y. 1997. The complete genome sequence of Escherichia coli K-12. Science 277:1453-1474.
3. Delcher, A. L., Kasif, S., Fleischmann, R.D., Peterson, J., White, O., Salzberg, S. L. 1999. Alignment of whole genomes. Nucl. Acids Res. 1;27(11):2369-76.
4. Falkow, S. 2000. The good old days are now. Trends Microbiol. 8:198-199.
5. Galan, J. E. and Collmer, A. 1999. Type III secretion machines: bacterial devises for protein delivery into host cells. Science 284:1322-1328.
6. Hacker, J., G. Blum Oehler, I. Muehldorfer, and H. Tschaepe. 1997. Pathogenicity islands of virulent bacteria: Structure, function and impact on microbial evolution. Mol. Microbiol. 23:1089-1097.
7. Harrison, B. D. and Wilson, T. M. 1999. Milestones in the research on tobacco mosaic virus. Philos. Trans. R. Soc. Lond. B Biol. Sci. 29;354(1383):521-529.
8. Hunter-Cevera, J. C. 1998. The value of microbial diversity. Curr. Opin. Microbiol. 1:278-285.
9. Nicholas, H. B. Jr., Deerfield, II, D. W. and A. J. Ropelewski. 2000. Overview: Strategies for searching sequence databases. BioTechniques 28:1174-1191.
10. Simpson, A. J. G., F. C. Reinach, P. Arruda, F. A. Abreu, M. Acencio, R. Alvarenga, L. M. C. Alves, J. E. Araya, G. S. Baia, C. S. Baptista, M. H. Barros, E. D. Bonaccorsi, S. Bordin, J. M. Bové, M. R. S. Briones, M. R. P. Bueno, A. A. Camargo, L. E. A. Camargo, D. M. Carraro, H. Carrer, N. B. Colauto, C. Colombo, F. F. Costa, M. C. R. Costa, C. M. Costa-Neto, L. L. Coutinho, M. Cristofani, E. Dias-Neto, C. Docena, H. El-Dorry, A. P. Facincani, A. J .S. Ferreira, V. C. A. Ferreira, J. A. Ferro, J. S. Fraga, S. C. França, M. C. Franco, M. Frohme, L. R. Furlan, M. Garnier, G. H. Goldman, M. H. S. Goldman, S. L. Gomes, A. Gruber, P. L. Ho, J. D. Hoheisel, M. L. Junqueira, E. L. Kemper, J. P. Kitajima, J. E. Krieger, E. E. Kuramae, F. Laigret, M. R. Lambais, L. C. C. Leite, E. G. M. Lemos, M. V. F. Lemos, S. A. Lopes, C. R. Lopes, J. A. Machado, M. A. Machado, A. M. B. N. Madeira, H. M. F. Madeira, C. L. Marino, M. V. Marques, E. A. L. Martins, E. M. F. Martins, A. Y. Matsukuma, C. F. M. Menck, E. C. Miracca, C. Y. Miyaki, C. B. Monteiro-Vitorello, D. H. Moon, M. A. Nagai, A. L. T. O. Nascimento, L. E. S. Netto, A. Nhani Jr. , F. G. Nobrega, L. R. Nunes, M. A. Oliveira, M. C. de Oliveira, R. C. de Oliveira, D. A. Palmieri, A. Paris, B. R. Peixoto, G. A. G. Pereira, H. A. Pereira Jr. , J. B. Pesquero, R. B. Quaggio, P. G. Roberto, V. Rodrigues, A. J. de M. Rosa, V. E. de Rosa Jr. , R. G. de S·, R. V. Santelli, H. E. Sawasaki, A. C. R. da Silva, A. M. da Silva, F. R. da Silva, W. A. Silva Jr. , J. F. da Silveira, M. L. Z. Silvestri, W. J. Siqueira, A. A. de Souza, A. P. de Souza, M. F. Terenzi, D. Truffi, S. M. Tsai, M. H. Tsuhako, H. Vallada, M. A. Van Sluys, S. Verjovski-Almeida, A. L. Vettore, M. A. Zago, M. Zatz, J. Meidanis and J. C. Setubal. 2000. The genome sequence of the plant pathogen Xylella fastidiosa. Nature 406:151-157.
11. Tang, CM, Hood, DW, Moxon, ER. 1998. Microbial genome sequencing and pathogenesis. Curr. Opin. Microbiol. 1:12-16.


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I wanted to showcase a soft winters day for this post. After speaking to the amazing Polly, my beautiful wife Danica and myself found the perfect pose, perfect feel, and all around perfect outfits to help us create this feeling. I hope you all enjoy.
Hair: *Dura-Boys&Girls*49(Wood Bark)
Facial Hair: . : VyC : . Burns \ beard addon
Skin: -Belleza- Ashton Pale GG Bald
Shape: [BODY FACTORY] Enzo Shape (l) Mouth 01
Shirt: AITUI CLOTHING FACTORY – Romulus Top
Pants: !Grandeur! Pocket Rock Dark Pants
BackPack: AITUI – Ridgeway Bag: Back Style
Boots: Razor /// Johnny Rotten Boots – Male
Pose: !bang – Perfect For Me – The Mens Dept


text: As if Tim hasn't written enough on the subject, today he's teaming up with John S to break down the finale (and reunion!) of Survivor: Redemption Island. Was this season exciting? Was Rob a villain? Was Philip actually crazy? Who was better looking: Andrea or Ashley? And will Parvati be back next season? Click here and all these questions and more will be discussed and speculated on.


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- 3 Beds
- 4 Full Baths
Property TypeResidential – Condominium
SubdivisionFour Seasons Private Residences
Listing Date09/27/19
Year Built2010
AreaVail Village
Parking2 Car Assigned, 2 Car Deeded, Underground, Wheelchair Access
Property Description
Step inside the newest custom-designed residence at Vail's premier luxury resort, perched high on the 8th floor with ski slope views. Entertain in the spacious open layout, with great room, dining and hearth room offering ample space to relax and reconnect. Enjoy the open kitchen complete with marble island, master suite with south-facing balcony, and spa-like baths. At Four Seasons, discover how effortless life can be when you have legendary service and resort amenities at your fingertips.
Presented By
- Bus Route
- In Town
- See Remarks
- Walk to Slopes
- Mountains
- See Remarks
- Ski Slopes
- South Facing
- Cross Country Trails
- Golf-Public
- Hiking/Pedestrian Trail
- On Bus Line
- Pets
- Shuttle Service
- Tennis Courts
- Air Conditioning
- Cable Available
- Deck
- Elevator
- Fireplace - Gas
- Jetted Bathtub
- Steam
- Clubhouse
- Fitness Center
- Front Desk
- On Site Management
- Pets
- Pool
- See Remarks
- Shuttle Service
- Spa and Hot Tub
- Cable TV
- District Sewer
- District Water
- Electricity Avail.
- Natural Gas Avail.
- Phone Available
- Snow Removal
- Trash Pickup
- Common
- Forced Air
- Natural Gas
- Zoned AC
- Dryer
- Washer
Financial Information
Additional InformationDocuments
About Vail Village
Charming, pedestrian friendly Vail Village has everything you could need or want right at your fingertips. The heart of Vail is located at the base of the ski mountain, home to Gondola One, and has undergone a great transformation with the renovation and construction of dozens of properties. The Village, with its heated cobblestone streets and quaint European architecture, invites you to discover world-class fine dining, art galleries, local boutiques and luxury retail. In addition to the tremendous variety of shopping and dining, Vail Village hosts sporting and cultural events, festivals, and concerts year-round. These include the Burton US Open, The GoPro Mountain Games, Gourmet on the Gore, Sunday Summer Farmer's Markets, Bravo! Vail Valley Music Festival, Vail International Dance Festival and free winter and summer outdoor concert series at the stunning Solaris Plaza.
Area Market Data
5 Beds 6 Baths
4 Beds 4 Baths
3 Beds 4 Baths
5 Beds 6 Baths
4 Beds 4 Baths
2 Beds 2 Baths
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Copyright © 2020 Vail Multi List, Inc. (VMLS). The information displayed herein was derived from sources believed to be accurate, but has not been verified by VMLS. Buyers are cautioned to verify all information to their own satisfaction. This information is exclusively for viewers' personal, non- commercial use. Any republication or reproduction of the information herein without the express permission of the VMLS is strictly prohibited.
Listing courtesy of Slifer Smith & Frampton/Bridge


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16 January 2013 | News | By BioSpectrum Bureau
Bionomics seeks refund of $4.2 million as R&D tax incentive from AusIndustry
Singapore: Bionomics has lodged its FY 2012 tax return and registered with AusIndustry (on behalf of Innovation Australia) for the Australian R&D tax incentive. Bionomics anticipates that it will receive a R&D tax incentive cash refund of $4.2 million for R&D expenses incurred in FY 2012.
Further in 2012, Bionomics made submissions for advance findings for overseas expenditure to be eligible for the 45 percent R&D tax incentive. Bionomics has now received favourable findings from AusIndustry in relation to this overseas expenditure.
The advance findings, for $8.9 million in overseas expenditure over the three year period from July 1, 2011, are in relation to investment in BNC105 cancer drug clinical trials being conducted in Australia, US, Singapore and New Zealand and to R&D activities associated with its Alzheimer's disease drug candidate BNC375. Bionomics had previously reported in its 2012 annual report an estimated R&D tax incentive refund of $3.1 million for the year.
"Funds from the R&D tax incentive are welcome as they enable Bionomics to undertake the development of its innovative drug candidates in cancer and Alzheimer's disease internationally with great efficiency, enhancing our global competitiveness," commented Dr Deborah Rathjen, Bionomics' CEO and MD.
Bionomics anticipates that further submissions will be made in FY 2013 covering overseas investments in R&D across the company's entire portfolio of drug candidates including BNC101 that targets cancer stem cells in solid tumours such as breast, colon and pancreatic cancers and which is being prepared for clinical trials in 2014.


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Fitchburg man dies after baseball bat beating
Suspect being held on $1 million bail
MADISON, Wis. — A Fitchburg man has died after being beaten with a baseball bat in Mount Horeb.
The Dane County Sheriff's Office said 20-year-old Ryan M. Smith died Saturday morning at the University of Wisconsin Hospital in Madison.
Smith suffered skull fractures and lung injuries in the beating early last Tuesday. Authorities have said drugs may have played a role in the violence.
Authorities are holding Koalton Peterson, 18, on suspicion of attempted first-degree intentional homicide. Peterson's bail was set Friday at $1 million, but Assistant District Attorney Rachel Sattler delayed formally charging him Friday, saying the charge likely would be upgraded to homicide.
Peterson has claimed self-defense, and has another hearing set for this coming Tuesday.
To help cover expenses related to his injuries, a fund has been set up at Summit Credit Union.
Donations can be sent to:
Ryan M. Smith Medical Fund
Summit Credit Union
2939 South Fish Hatchery Road
Fitchburg, WI 53711