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(Pocket-lint) - The rush to sell you headphones pushes on unabated. The thinking seems to be: for the time being people are prepared to spend £200 on headphones, it won't last forever, so let's make some money. And when there's demand, you'd be crazy not to try to satisfy it.
Focal is an audio specialist, although headphones are not the primary focus of what it has done until now. Mostly it sells high-end speakers to home cinema enthusiasts, or studio monitors to recording studios. So while headphones might be new for the company, high-end audio most certainly is not. So has the company cracked it with these, are they worthy of your attention over the dozens of other pairs of over-the-ear cans on the market?
White, or even black
We're testing the white headphones, which were introduced before Christmas, but there's also a black set which are the same and have been about for a bit longer. The white headphones are, dare we say it, a shot at the fashion-conscious headphone user. We don't want to say Beats too much in this review, but let's be honest, there's a lot to be said for that firm's love of white headphones.
READ: Beats Pro review
The Spirits are quite nicely put together. There's a lot of plastic used here, but it's highly polished and it looks good. We love the red inlay on the inside of the headphones too. There's a soft band at the top which keeps them nice and comfortable on your head. The earpads themselves are well-cushioned too, and they compress to fit your head nicely too.
One thing we did notice was that the grip of the headphones against your head is pretty substantial. This keeps the headphones in place when you're listening to music, and doing a Will Smith-style head roll. That's good, but it can make wearing them for a long time quite tiring. We aren't crazy about the adjustment band, it does the job, but we seemed to struggle a lot with it. Most of the time, this is simple to adjust on headphones, but on the Spirit Ones it just seemed harder to find that sweet spot.
The Spirit Ones fold up too, so you get a compact arrangement that fits more easily in to a bag. We like the fact - as always - that the audio cable is removable too. This is easily the part of headphones most likely to fail, so when it can be replaced it means no tedious argument about warranties: just buy a new cable for a few quid.
As with most headphones, there's a soft case included - and a hard one too, for that matter. The old airline adapter is thrown in, as a 3.5mm to 6.5mm "embiginator" - that's a real word, honest.
More exciting though, is the inclusion of the remote control cable. This is like the standard cord, but contains a microphone and controls for the usual functions. This will work on an iPhone for sure, and some of the features will also work on other devices. We usually find that the microphone is fine on phones - and laptops for that matter - but the volume control is usually limited to Apple devices. Still, you get a choice, so you can pick the one that suits your needs best.
Sound quality
First of all that terrific noise isolation really helps with the quality. Blocking out as much external sound as possible means you get to hear your music without any alteration. That's a really important thing, and scores over noise cancellation, because it does not introduce noise into the audio.
Music quality is superb too. There's quite a flat sound here, with the headphones having no easily detectable bias toward either the low, or the high end. If anything, they seem to like the mid-range, but it's nothing too devastating and the overall quality is solid and the range seems impressive.
One of the first tests we give a pair of headphones now is to play a track we know is right on the edge of acceptable when it comes to the high end. For whatever reason, there are some tracks that on some headphones just sound a mess. The Focals, however, manage it well. There's still some obvious shimmering, but that comes down to the source material.
TV and movies too, sound pretty terrific. When it comes to bass, they hide their light under a bushel to some extent, because they're quite conservative. But give them some bass from an action film and they hold up well. This is all good, because no one wants their headphones inventing bass, but everyone does want a faithful reproduction of what the musician or director intended.
We really like the Focal Spirit headphones, they have a sound that is very appealing. If we had to be concise, we'd say they sound "just right". There's no time when we felt one bit of the sound had too much of any one component, or not enough of any part of the frequency range.
In terms of comfort, they lose a tiny bit because they aren't all that easy to adjust, clamp quite hard and have cups that are fractionally too small for our ears. None of these things is a major issue, but it might make listening for extended periods a bit more bothersome.
Overall though, we can't really fault the Focal Spirit Ones. The noise isolation is super, the sound is great and they really look great - although we'd buy in black. The only issue is that they're not as comfortable as some to wear, but if you're out and about, you'll be pleased to have them clamp your head.


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2 friends of accused Boston Marathon bomber charged with obstruction
Two friends of Dzhokhar Tsarnaev, accused of bombing the finish line area of the Boston Marathon, have been indicted by a federal grand jury on charges of hindering the investigation into the attack.
Dias Kadyrbayev and Azamat Tazhayakov, both Kazakhstan nationals, were charged with conspiracy to obstruct justice and obstructing justice, U.S. Atty. Carmen Ortiz in Boston announced on Thursday.
The men were originally charged in a criminal complaint on May 1.
PHOTOS: Manhunt for bombing suspects
If convicted, Kadyrbayev and Tazhayakov, both 19, face up to 20 years in prison on the obstruction of justice count and up to five years in prison on the conspiracy count, as well as a $250,000 fine. Both also face the possibility of being deported, if convicted.
The pair, who are currently in federal custody, went to the University of Massachusetts-Dartmouth in 2011, as did Tsarnaev, 19. Kadyrbayev and Tazhayakov had entered the United States on student visas and were living in New Bedford, Mass., during the bombing on April 15.
Three people were killed and more than 260 were injured when two pressure-cooker bombs exploded along the finish line area on Boylston Street.
On the evening of April 18, the FBI released photographs and surveillance video of the two suspects, Dzhokhar and Tamerlan Tsarnaev, as part of an intense manhunt that shut down the metropolitan Boston area. According to the indictment, Kadyrbayev, after the release of the images, received a text message from Dzhokhar Tsarnaev suggesting that he go to Tsarnaev's college dormitory "room and take what's there."
Kadyrbayev, Tazhayakov, and another person then went to Tsarnaev's dormitory room and removed several items, including Tsarnaev's laptop computer and a backpack containing fireworks. Later that night, Kadyrbayev, with Tazhayakov's "knowledge and agreement," placed Tsarnaev's backpack, which contained several items including fireworks, in a garbage bag, and put it in a trash dumpster outside their New Bedford apartment, according to the indictment.
In the statement announcing the indictment, prosecutors referred to a third person, whom they did not identify.
However, the person is Robel Phillipos, who has been accused of lying to FBI agents investigating the aftermath of the bombing. Phillipos has not been indicted and in court papers filed Thursday indicated that his attorney and the government were in negotiations to deal with his case.
Phillipos is under home confinement and must wear an electronic bracelet, federal officials said. Tamerlan Tsarnaev, 26, was shot and killed by police during the manhunt.
Dzhokhar Tsarnaev was taken into custody after he was found in a boat in the backyard of a house in Watertown, Mass.
Dzhokhar Tsarnaev is currently being held without bail on federal charges that include using a weapon of mass destruction. If convicted on the most severe charges, he could be sentenced to death.
On July 10, Dzhokhar Tsarnaev pleaded not guilty to 30 charges in his first public court appearance, including a murder charge for MIT police officer Sean Collier, who was killed when the brothers tried to flee.
4 killed, 4 wounded in Dallas-area shootings
Hasan trial at Ft. Hood will go forward, judge rules
'Dream 9' members are freed while they pursue asylum
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subset: commoncrawl


text:
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text:
Hi Seth
I take a few days to try your Game engine and I must say that the editor is quite impressive and brilliant !
Aside from one or two ergonomic additions (and better visual assets maybe ) it would be perfect
But when I try to delve a little bit more under the surface to see what type of games you could build thanks to Lua, I missed a few important things.
The most important one was the lack of Box2d functionalities to handle any simulation.
Do you still plan to implement the features of that particular engine ? That would be great.
You also wisely choose Clanlib and I was wondering if you plan to expose a few more things from that great "Toolkit" in a near future ?
By the way, which version of Box2d and Clanlib, Novashell is currently based on ?
Of course, it is still possible to play with C++ to directly use what's missing, but I'm not that good at C++ and Clanlib can be so complex sometimes that I would miss the whole point of using Novashell I think. Probably simple Lua is good enough to handle the whole game.
Finally, is Novashell ultimately designed for RPG/adventure ?
Because with such unique set of features I think that Novashell really doesn't miss a lot to build great others 2D type of games !


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« Communism | Main | The End of Illusion – The danger of intermediaries »
Indictment of Bush Officials May Come in Days
From Pinochet to Bush, the Path to Prosecution
* The imminent indictment in Spanish courts of former officials of the Bush Administration is being applauded by civil and human rights organizations and legal scholars. The popular wave of support for indictment of Bush officials will inevitably lead to Bush himself.
* Newsweek Magazine blew open more shocking news about Bush' system of kidnapping, secret prisons and torture. A secret Red Cross report indicates that many kidnapped and tortured people were turned into "disappeared persons" by the CIA under instructions from Bush and Cheney. A former Bush administration official told Newsweek's Michael Isikoff that the information had been hidden from the Red Cross. "The majority of the people in the CIA program are unaccounted for. We don't know what happened to them," a human rights investigator told Isikoff.
* Like Bush, former Chilean dictator Augusto Pinochet, thought his power would shield him from criminal prosecution when his regime kidnapped and tortured and assassinated individuals who became known as the "disappeared." It was when Spanish courts brought indictments against Pinochet that everything changed. As Michael Ratner, president of the Center for Constitutional Rights said, "the importance of this investigation [in Spain] can not be understated. Contrary to statements by some, the Spanish investigations are not 'symbolic.' Just ask Augusto Pinochet, who was stranded under house arrest in England and who ultimately faced criminal charges in Chile because of the pressure of the Spanish courts. If and when arrest warrants are issued, 24 countries in Europe are obligated to enforce them. The world is getting smaller for the torture conspirators."
Ramsey Clark, former U.S. Attorney General has called for the prosecution of Bush and other high officials in the United States, stating, "The greatest danger arising from impunity for President Bush and his cohorts would be that all subsequent officials will feel secure in committing the same crimes and the people, having failed to compel impeachment for such open, notorious and egregious crimes, will feel even more helpless to prevent them. Ultimately the power and the responsibility to prevent criminal acts by government is with the people."
Now is the time for massive outreach and publicity. This requires newspaper ads, organizing national call-in days to pressure Congressional representatives, intensive media work, teach-ins and educational forums, and providing literature for people of conscience to distribute in cities and towns across the country. Please consider taking a moment right now to make a donation to this new movement for the indictment of Bush. There is no time to spare. The time to act is now and we will.
--All of us at IndictBushNow.org
April 19, 2009 in Current Affairs | Permalink
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One of my desktop system has Radeon 1550 PCI card with 256Mb ram (I'm using Radeon driver from X.org) . I'm looking to upgrade it to ATI Radeon HD 3800 series PCIe card. Now AMD has released the ATI Catalyst Linux Graphics Driver software suite version 8.493.
For further information and driver download visit the ATI website.


text:
- Description
Product HighlightsRegister boots provide a transition from round duct to a rectangular opening for a floor or ceiling register. Available in 45°, 90°, Straight, Center End, and Right and Left Hand End variations.
California residents: see Proposition 65 Warning
- Specifications
Weight 0.10 Pounds Length 10.00 Inches Width 4.00 Inches Height 9.00 Inches Country of Origin USA Brand Southwark R-Value Not Insulated Flanged No Galvanized Yes Diameter 4" Color Silver Composition Galvanized Steel Gauge 30 GA Insulated No Size 4" x 10" x 4"
To see the pricing of the equipment you need to be a licensed provider. Click here to become a licensed provider.


text:
The attached receipt refers to the 1930's as it shows the payment of Rs. 6/- done by Lt. Shri Keshar Singh Rai of Namchi Sikkim as Dhuri Khazana (House Tax) to the Mandal of Namchi, Lt. Chandra Man Rai on 15/09/1930.
Reviewed and posted on 30/4/2010
A blog related to history culture and heritage of the erstwhile Himalayan Kingdom of Sikkim
Sikkim- A Look Back View All Rights Reserved
Blogger Templates by Deluxe Templates • CSS by Free CSS Templates.


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National Geographic Photographer Annie Griffiths to Speak on Campus Nov. 16
Augustana College today announced that Annie Griffiths, one of National Geographic's first female photographers and an artist known around the globe, will share video, photos and reflections on her life, career and experiences in a discussion titled "Connect with Anybody, Anywhere" at 8 p.m. on Wednesday, Nov. 16, in Kresge Recital Hall.
Admission is free for those with an Augustana ID; $5 for the general public.
Griffiths' visit coincides with "International Education Week" at Augustana, a collection of programs, meals and discussions that celebrate global diversity.
Griffiths has photographed in more than 100 countries during her illustrious career. She has worked on dozens of magazine and book projects for the Society, including stories on Lawrence of Arabia, Baja California, Galilee, Petra, Sydney, New Zealand, and Jerusalem.
In addition to her magazine work, Griffiths is deeply committed to photographing people and places in need around the world. She is Founder and Executive Director of Ripple Effect Images a collective of photojournalists who are documenting climate change's effects on people in need, and the programs that help poor women deal with these effects. Griffiths is a Fellow with The International League of Conservation Photographers.
"Connect with Anybody, Anywhere"
Featuring Annie Griffiths,
National Geographic photographer
- 8 p.m. Wednesday, Nov. 16
- Kresge Recital Hall
Free with a valid Augustana ID; $5 for the general public
Griffiths' work has also appeared in LIFE, Geo, Smithsonian, Stern, TIME and many other publications. With author Barbara Kingsolver, Annie produced "Last Stand: America's Virgin Lands," a book celebrating the last pristine wilderness in North America. Proceeds from the book have raised more than a quarter of a million dollars for grassroots land conservation. Last year, Griffiths published "A Camera, Two Kids and a Camel," a photo memoir about balance, and the joy of creating a meaningful life. Her newest book, "Simply Beautiful Photographs" was published in October 2010.
Griffiths has received awards from the National Press Photographers Association, the Associated Press, the National Organization of Women, the University of Minnesota and the White House News Photographers Association. She lives in Great Falls, Virginia, with her two children.
The event is sponsored by AIC, UBG and ASA.


text: Greetings fellow fantasy geeks! Tis I, Tehol Beddict, here yet again to service you in ways you once thought irrealizable. I'm merely perpetuating my own genius by coming week after week with top quality, grade-A knowledge. I got's to drop it on ya'll, for not tot would be a terrible waste as it would die like a fart in the wind. At long last I've reawakened from my Vegas slumber as the elder gods were terribly unkind to me this trip. Of course, that is if you call doing mass quantities of snow with with a pack of bodacious strippers until the birds started chirping unkind. Beyond a doubt the sort of excursion that would make even the great Charlie Sheen jealous. Now let us get to the point of this post. I'm not here to write to you of perfectly formed beauties riding me like a rodeo (or am I), nor am I here to glorify hard core drug usage. What I've come here to do today, is talk about Alex Rodriguez, for I am seemingly his last remaining fan on earth.Please, blog, may I have some more?


text:
Daisy Daisy,
Give me your answer do!
I'm half crazy,
All for the love of you!
It won't be a stylish marriage,
I can't afford a carriage,
But you'll look sweet on the seat
Of a bicycle built for two !
ADDENDUM: The VV would like to add this small but charming post which shows Victorian ladies on bicycles - as stately as any galleons.


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You tend to think of Nerdcore rappers as having come out of the world of geek culture and then getting into rap — rather than starting out in hip hop and then starting to rap about nerdy stuff. But Richie Branson (aka Marcus Brown) started out producing rap albums for Def Jam and Sony — and then he decided to get into nerdcore. He's created downloadable mix tapes about Star Wars: The Old Republic (called "The Cold Republic") and Gundam Wing (called "Wing Zero Mixtape") and you can listen to one of his Gundam songs above.
Branson tells My San Antonio that he tried rapping about cars or girls, but it wasn't until he was playing The Old Republic and took a bathroom break while listening to the video game music that he hit on his subject matter. After that, he says, "I finally had found my identity as a musician."


text:
The Toronto Raptors rested Kawhi Leonard, Kyle Lowry, Danny Green and Serge Ibaka in their final game of the preseason.
Their teammates made sure they could enjoy the break with a victory.
Malachi Richardson and Pascal Siakim each scored 21 points, and the Raptors beat the New Orleans Pelicans 134-119 Thursday night to wrap up the preseason with a 4-1 record.
Leonard, Green and Ibaka all played in the Raptors' game in Montreal on Wednesday night, so they were given a game off with the travel to New Orleans.
Anthony Davis had a game-high 36 points and 15 rebounds for the Pelicans, who concluded a winless preseason. The Pelicans had everyone available, even though they didn't get home from a road loss in Miami until after early Thursday morning.
The Raptors led 67-64 at halftime and never trailed in the second half, building their lead to as much as 15 in the fourth quarter.
New Orleans pulled within 111-109 with 7:39 left on a layup by Darius Miller. The Raptors finished the game on a 23-10 run.
Raptors forward Chris Boucher left the game with just more than eight minutes left after a collision with Davis as both players leapt into the paint for a rebound. Boucher landed horizontally and his head appeared to strike the court. He remained down a couple minutes while he received treatment and needed help walking to the locker room.
Raptors spokesman Roven Yau said after the game that Boucher "passed the NBA concussion protocol and will continued to be monitored."
Thursday's games:
Davis scored 23 and grabbed eight rebounds by halftime. Siakam had 20 of his 21 points in the first half, and his two free throws with 50.6 seconds left gave Toronto the lead for good at 65-63. Siakam banked in a hook shot with 2.4 seconds left for a 67-64 halftime lead.
RAPTORS: Siakam also had 11 rebounds and six assists … Kay Felder and OG Anunoby each added 15 points, CJ Miles had 14 and Jordan Loyd and Eric Moreland had 12 apiece. Moreland also had 10 rebounds.
PELICANS: Julius Randle had 13 points by halftime and finished with 20 points. He also had 11 rebounds. … Nikola Mirotic had 15 points and Jrue Holiday had 14. Darius Miller came in 10 of 13 from 3-point range, but he cooled off a bit missing all six shots beyond the arc. … Jahlil Okafor sat out the game with a sprained right ankle, and Alexis Ajinca also was out with a strained right quadriceps.
UP NEXT: Toronto hosts the Cleveland Cavaliers on Wednesday in the Raptors' season opener. New Orleans opens the season Wednesday at Houston.
Rudy Gobert scored 18 points and grabbed seven rebounds in the first half, and Utah cruised to its fifth straight win.
Utah jumped out to a 22-4 lead and extended it to 71-35 by halftime. Gobert was 7-of-8 shooting, Donovan Mitchell scored 13 points in the half and Jae Crowder added 12. It was 101-72 at the end of the third quarter.
Second overall pick Marvin Bagley III led the Kings with 17 points.
JAZZ: Utah shot 64 percent from the field in the first half, including 7 of 16 from 3-point range, and held Sacrament to 25.5 percent shooting. The Jazz also outrebounded the Kings 31-14 before halftime. … Rookie Grayson Allen scored all 14 of his points after halftime.
KINGS: Buddy Hield was 2 of 10 from the field in the first half and Bagley was 3 of 10. … Newcomer Iman Shumpert played his first minutes for Sacramento and scored two points. Fifth overall selection De'Aaron Fox made 1 of 10 shots for four points.
UP NEXT: Utah (5-0) plays at Sacramento to open the season on Wednesday. Sacramento (2-3) plays at Portland on Friday.
Boban Marjanovic had 18 points and 12 rebounds, and the Clippers closed out their undefeated preseason schedule.
Los Angeles led 70-35 at halftime behind Marjanovic's 14 points and eight rebounds, and Montrezl Harrell's 12 points. The duo combined to make 13 of 15 shots in the half.
Roman Sorkin scored 12 points for Maccabi Haifa.
CLIPPERS: Danilo Gallinari was the only Clipper starter to score in double figures with 12 points. … It was 94-42 entering the fourth quarter. … Eleventh overall pick Shai Gilgeous-Alexander had six of his seven assists in the first half.
UP NEXT: Los Angeles (5-0) hosts Denver on Wednesday.
More AP NBA: https://apnews.com/tag/NBAbasketball and https://twitter.com/AP-Sports
25% Bonus via Western Union


text:
Veteran Republican U.S. Rep. Tim Johnson of Urbana, viewed as almost certain to win another term in November, will announce as soon as Thursday he is not seeking re-election, sources familiar with the Republican lawmaker's decision said Wednesday.
The congressman, known for extensively phoning and traveling to visit with constituents, has grown unhappy with the job, according to one source long familiar with Johnson and Republican politics.
In addition, Johnson, who has a fitness regimen, became concerned about his own health after the recent stroke suffered by Republican U.S. Sen. Mark Kirk, the source said.
Another source said Johnson felt comfortable stepping down after David Gill, a Democrat from Bloomington, won the Democratic primary last month. Gill had run and lost against Johnson three times previously.
Latest Politics
Johnson, a former state lawmaker first elected to Congress 12 years ago, has always marched to his own drummer.
He was the lone GOP member of Congress not to join an ultimately unsuccessful federal lawsuit challenging the Democratic redrawing of the state's congressional districts. Johnson also was one of only a handful of members of Congress across the country to back Ron Paul's bid for the GOP presidential nomination.
A list of potential replacements for Johnson on the November ballot rapidly developed.
Names being discussed include state Sen. Bill Bradyof Bloomington, the unsuccessful 2010 nominee for governor, state Rep. Chapin Rose of Mahomet, who won nomination to the state Senate last month, former state Sen. Duane Noland of Blue Mound, Johnson's former chief of staff Jerry Clarke, and Rodney Davis, an aide to U.S. Rep. John Shimkus of Collinsville, who has worked on congressional get-out-the-vote efforts for the state GOP.


text:
For everyone else stay tuned for our next weekly giveaway! WOOF!
Get your Polka Dog Bakery Treats
How to Enter
1. Follow PawLuxury and PolkaDogBakery on Twitter.com
2. Retweet to your friends - Copy and paste this into Twitter:
|www.pawlux.com Giveaway @PawLuxury & @PolkaDogBakery are giving away Holiday Dog Treats http://pawluxury.blogspot.com Comment to enter.
3. Leave a comment at pawluxury.blogspot.com with the following:
* Recommend a new Treat Flavor for Polka Dog Bakery.
Do those three steps to enter. (one comment per person)
There will be 1 winner for 2 cans of treats (2 flavors per can) $30.00 Value
Contest ends 1/9/09 at midnight (You have 1 week to enter)
Winner announced 1/10/09
Winner chosen by random number generator.
About Polka Dog Bakery.
Polka Dog Bakery was rated Best of Boston 2008
If you're in the Boston Area, stop by
Polkadog Bakery
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If you can't get to Boston, you can find healthy Polka Dog treats at www.pawlux.com


text:
DAMASK & FLEUR Stamp
Create your edible delights with Stamp a Cake, the easy way to transfer gorgeous designs with edible ink onto fondant cakes, cookies and cupcakes.
Stamps are made from food grade material, and have been specifically designed for use in cake decorating.
Contains 6 different damask & fleur stamp designs.
Other Stamp a Cake stamp designs available.
NB - Apply stamp designs to your edible treats using Stamp a Cake's inks, specially formulated to work with the stamps (note - regular gel pastes and other colours will not work) and the easy to use Stamp a Cake Edible Ink Roller and Acrylic Stamp Holder.


text:
Actress Melanie Griffith has checked herself into a rehab facility for the third time, the star's representative said Monday.
Griffith, 52, is staying at the Cirque Lodge in Utah, the celebrity rehab enclave that's hosted Hollywood elite like Kirsten Dunst and Lindsay Lohan as they recover from addiction.
Griffith checked into the Cirque Lodge for routine treatment to deal with her past addictions, Griffith's rep told Entertainment Tonight.
U.S. & World
"She is there to reinforce her commitment to stay healthy," Griffith's rep said. "This is part of a routine plan that was designed between her and her doctors years ago."
The mother of three and wife of Antonio Banderas has been to rehab twice before. She visited a facility in 1988 to battle an addiction to alcohol and cocaine and was also treated in 2000 for her addiction to painkillers.
Griffith is known for starring in films like "Working Girl," which earned her a Golden Globe and an Academy Award nomination. She's the daughter of Tippi Hedren, muse of director Alfred Hitchcock and star of "The Birds."


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A healer technique into which I stumbled
I am, as I've noted before, not the top heal-person in my guild. And as I've also noted, we're… surprisingly heavy in healers (in a lot of ways, with some peculiar exceptions such as the "heavy" is paladins). Anyway…
Because we're so heavy in paladins, there's an interesting development which has, for lack of a better word, "happened". Basically, Healadins get assigned to Tank Heal – not least because they are unsurprisingly resistant to the consequences of getting too close. (And if they pull aggro, they don't … squish as easily.) We've also got a couple of healing Druids. So here's what happens…
Healadins have The Tanks, plus a bit of watch on others nearby. Druids have the Big Group. And me, the priest? I am – shockingly – the safetynet. I cast almost zero Greater Heals. It's all speedwork to hold the fort till the other guys catch up.
I was in a raid the other night, and almost 3/4 of my casts were renews. One of the biggest reasons for the renew was a lot of damage was DOT damage. I wasn't really healing anyone from the damage of which the DoT was a followon. What I was doing was holding the line till the other healer could fix the rest of it.
Most of the rest? Flash. Plus tossing the occasional frisbee to the main tank. A prayer of mending once or twice.
Now there happens to be two very, very nice benefits to this tactic as well as a couple of frustrations. Benefits first.
a) My aggro level was tiny. I, the squishy healer, only got touched by randoms or AoEs. (When a mob spawns next to you just as your four renews tick, you ARE George. It's something on which I'll have to work, later.)
b) I had a huge manapool remaining later in the battle. Sure, I'd do flurries of spam-renew, but then I'd be dancing the five second waltz. And since I use a lot less mana for renew than GH, the dance didn't need to go as long before I was ready again. Which meant that when one of the frontliners gave a LOM/OOM call, I was able to hold for a bit till they re-upped. Of course, since they were getting these bumps from my renewals they weren't going out as fast, either.
Altogether a very viable technique. As I said, there are frustrations.
a) numbers always matter to some people. Little heals means little numbers means… teaching certain decision makers that Quality of heals is -for healers – more important than Quantity. Which is harder since Renew inevitably has an overheal. Slightly countering this? My overheal rate for renew was under 10%. The AoE and DoT and other spread damage was coming frequently enough to make renew's later ticks used instead of wasted.
b) I really, really want Circle of Healing, even as gimped as it is. It fills a desperately useful supplement for this technique But to do so I would have to give up Improved Divine Spirit, and the casters have come to be really fond of the extra spelldamage. Even more important, giving it up would cut deeply into my mana regen. 23 in Disc and 41 in Holy is 64 is, well, three talent points too many. mutter. mutter.
Anyway, feel free to share techniques you've done, used, or encountered. Or improvements, or…
4 Responses to "A healer technique into which I stumbled"
Do it Kirk! Spec Circle of Healing! 😀 You might like in raids, you never know until you try. Unless you're the only Priest with Imp. DS in which case, fights might go 10% longer then they would otherwise. Oops.
But yeah, isn't it great to just sit there and renew with your mana maximized? The lack of aggro grain is also to die for. You're sitting in there with tank aggro at some obscene high number like 113k while yours is at 40k or something.
While you're right on the fact that our numbers may never surpass a Paladin's in terms of healing, at the end of the day, the boss is dead, right?
Honestly, I would love to have a priest go CoH. Paladins and druids specialize in covering tanks. But there are a lot of fights where many people take splash damage, and having someone good at cleaning up splash damage for multiple people at a time is ideal. Shamans with chain heal or priests with CoH are awesome at this.


text:
Sometimes when you get an itch, it just has to be scratched. Mike Yale works as the parts and service director for Mercedes-Benz of Houston and sees (and experiences) first-hand a lot of fine-handling European cars. After going to a Goodguys show and watching the autocross competition, Mike got the bug to do some cone dodging. An experienced NASCAR late-model racer, Mike was no stranger to turning the wheel, though his new endeavor would involve more than just turning left. For a car he knew it had to be a Camaro, but he didn't want a first-gen like everyone else. That left the swoopy fastback second-gen as his choice to build a Pro Touring machine.
Mike picked up his '70 in the spring of 2008. At first he thought he was getting a fairly decent starting point to build the car he wanted for autocrossing. After tearing it all apart, the ugly truth became apparent. The only parts of the F-body without rust were the floors, trunk, and doors. Undaunted, he enlisted the help of Mike and Jeff Cassidy for installing all new metal. Once the body was ready, Ron Spencer wheeled it into the paint booth for primer and coating with Mercedes Brilliant Silver with clearcoat.
With the body ready, it was time to pick and install the right suspension. There are a lot of options out there for Camaros of this vintage, but after Mike went for a ride with Kyle Tucker in Detroit Speed's '70, he knew then and there what he wanted to install. For the front, a complete DSE front subframe was installed. The subframe utilizes DSE's own suspension geometry design that improves camber and other aspects over the stock system. The subframe features hydroformed framerails with stamped crossmembers, tubular control arms, rack-and-pinion steering, coilovers with Afco adjustable remote-reservoir shocks, splined sway bar, and C6 Corvette steering knuckles and wheel hubs. The last part means that any C6 brake system will work with the DSE front subframe.
In the rear is DSE's QuadraLink suspension system. This design pitches the Camaro's stock leaf springs in favor of a four-link setup with Panhard bar and coilover shocks. It features adjustable upper and lower control arms for a wide array of suspension tuning options, depending on track conditions and car setup. Just like the front, the shocks for the coilovers are Afco adjustable with remote reservoirs. All of this is located around a 9-inch rear with 3.89 gears and Tru-Trac limited-slip system (assembled by Pyle Brothers Performance Differentials in Baytown, Texas).
To make sure the Camaro doesn't lose it under hard deceleration, the brakes at all four corners are Wilwood, 13-inch rotors all around, with six-piston calipers fore and four-piston calipers aft.
With the rolling chassis complete, the rest of the drivetrain needed to be selected and installed. Mike's first two engines were locally built LS3s that didn't live up to expectations. By expectations we mean actually surviving the abuse of autocrossing. When we first photographed Mike's Camaro, it had ungodly death knock coming from the bottom end. Tired of being hobbled by engine troubles, he went to Mast Motorsports for a 416-inch, LS3-based stroker with Mahle pistons, Callies forged crank, and other heavy-duty goodies. On the dyno the engine made 590 hp at 6,300 rpm. The front accessory drive is a Vintage Air Front Runner system, and keeping Mike cool during his fun is a Vintage Air climate unit. Spent hydrocarbons are expelled through Lemons 1-7/8 headers and custom-fabbed 3-inch stainless steel exhaust with Borla mufflers.
To get the car dialed in and rack up some experience, Mike would hit every open track day he could find within reasonable driving distance of his home. Once everything was set, the Camaro was entered in the Fort Worth Goodguys show and won the autocross event, earning him a spot in the 2009 Optima street car invitational. Even though Mike and his "budget" Camaro were surrounded by high-dollar machines, the '70 acquitted itself well, finishing 14th and making Mike very proud to score that high while running against all the "big dogs" in the competition.
Not one to leave things alone, Mike has continued to improve the Camaro and make it an even better machine. When we photographed the car, it had the pictured set of Rushforth Whiplash wheels installed. Since then, they've been swapped in favor of Rushforth Overkills. For extra safety and strength, a Dooley & Sons custom cage has also been installed. Then two months before the '70 showed up at our 2011 Houston Super Chevy Show, Mike scored a pair of NOS fenders that he had installed and sprayed to match.
This Camaro is a superb piece, built and then driven like it was meant to be. When the results from our 2011 AMSOIL Best of the Best national online competition came in, Mike's car was voted the top entry in our Camaro class.
Good looks combined with real performance always equals winning.


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"Roy the Redeemer" was unveiled this week, a massive statue of England manager aping the famous Christ sculpture in Brazil. He stands above the cliffs of Dover, and is supposedly visible from France. (The two nations face each other on Monday.)
The statue is the work of online bookmaker Paddy Power, an Irish company, so this is more about PR than nationalism for them. But it's funny! So here's a link, Paddy Power. Rio Ferdinand will probably just avoid the entire South of England.


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amazincc wrote:Oh.
We got the same diagnosis... chances "slim to none". I heard "treatable" and "slim" (which IS something), and so I didn't even have to think about it.
What about the treatment isn't "fair" though??? Faust was on IV fluids and meds (also somewhat sedated, in case of pain)... so, I don't think he suffered MORE because of it???
What does your vet know that mine doesn't?
I dont think my vet knows something yours doesnt - it was a personal choice that I discussed with my vet. The treatment is intense (as you know) and to put him through the stress and pain with him being that sick and only having a marginal chance - I feel it was the right thing to do in the given situation.


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On the final installment of "Sarah Palin's Alaska," which aired Sunday on TLC, the presidential wannabe went panning for gold.
"Does it come down to who works hardest or who's the luckiest?" Palin asked her gold-mining guide.
It's enough to leave you wondering whether the prospecting scenes simply reflect the latest Palin Family outdoorsy fun or serve as a convenient metaphor for her political aspirations (or both). But the images of Palin going for the gold undoubtedly delivered an apt end to an often fascinating show that yielded plenty of pyrite amid gems offering varied (and not always flattering) reflections of the woman who would be president.
U.S. & World
Never before has an American TV audience spent this much time, unfiltered by the press, with a prospective leader of the free world and her family – albeit through the fun-house mirror that is the lens of Reality TV, the fuzzy lingua franca of this strange era in television.
During the eight episodes (plus a one-hour retrospective special with outtakes), viewers got welcome glimpses of the undeniably beautiful Alaskan landscape, which provided a scenic stage for lots of kayaking, camping, hiking fishing and even lessons in logging.
But the series wasn't an infomercial for Alaska as much for Palin, who might not really be able to spot Russia from her window – but you betcha she can see clear all the way to the White House.
The images of an attractive family amid the stunning backdrop proved at times powerful – and entertaining as they sloshed their way through some bumpy white water rafting, spotted battling bears and gutted fish. We can never know what happens when the cameras are off, but there seems to be affection among the family members, who possess an impressive energy.
Nine-year-old daughter Piper, in particular, comes across as an outspoken, independent spirit who's a natural in front of the camera – perhaps because she's spent a larger percentage of her life in front of them than the older members of her family. When Sarah Palin tearfully talks about her hopes for her 2-year-old son, Trig, who has Down syndrome, she genuinely connects with the audience as a caring mom.
But much of the positive impact was blunted by Palin playing her Mama Grizzly character, shooting from the hip, verbally and otherwise. We witnessed her gun down a caribou, fire at a charging wooden bear target on wheels – and take a gratuitous pot shot at Michelle Obama's efforts to fight childhood obesity, painting the First Lady as an elitist enemy of s'mores.
"This is in honor of Michelle Obama, who said the other day we should not have dessert," Palin declared as she collected s'mores ingredients during a family camping trip.
The line, like much of the purportedly unscripted show filled with outdoorsy activities and folksy charm, seemed calculated to build on the scrappy hockey-mom/political maverick persona Palin began cultivating when she was thrust into the nation spotlight in 2008. Palin is determined to present herself as the next Ronald Reagan, and she clearly has used to the program to project bygone Reaganesque notions of rugged individualism, with a God-helps-those-who-help-themselves subtext that was as unrealistic then as now.
In the first episode of "Sarah Palin's Alaska," the former GOP vice presidential candidate told us that she and her family are "normal, average everyday Americans" – which, no matter what you think of her, is, at this point in their lives, untrue.
It's unclear, though, whether the show, a kind of Rorschach test wrought in snow, will change anyone's mind about Palin or just reinforce previously held opinions.
A recent poll by Public Policy Polling found that 58 percent of Alaskans hold an unfavorable view of their former governor. Her debut show drew 5 million viewers, a TLC record, and settled into an average of 3.2 million – hardly "Jersey Shore" numbers (last week's third season premiere attracted 8.45 million viewers), but very respectable.
The ratings probably will turn out to be strong for the "Sarah Palin's Alaska" finale, most likely because of well-timed recent reports the program won't be back for a second season. That may be the strongest signal yet that Palin will run for president. Perhaps she's taking old-school GOPers' criticisms of her as a reality show lightweight to heart, and she'll instead stick largely to her online and Fox News platforms. Or maybe there's another Palin plan in the offing.
She may not have the following of Snooki or even her recent guest star, Kate Gosselin, but Palin's Reality TV gambit already might be inspiring others. Donald Trump revealed last week that this season's "Celebrity Apprentice" finale could include an announcement on whether he's hiring himself as a 2012 presidential candidate.
Time will tell whether we've reached the sad point where having a Reality TV show is a mandatory step along the yellow brick road to the White House – or just another path covered in fool's gold.
Hester is founding director of the award-winning, multi-media NYCity News Service at the City University of New York Graduate School of Journalism. He is the former City Editor of the New York Daily News, where he started as a reporter in 1992. Follow him on Twitter.


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We are pleased to announce that we are now offering our full product range without restrictions. Due to unprecedented demand with our delivery partners, we are advising to allow additional time for delivery.
The Telegraph Team
Land remote sensing: the use of space-based satellite technologies to obtain information on environmental variables such as land-use and land-covering combination with other types of data can provide information on changes in the Earth's surface and atmosphere that are critical for forecasting and responding to human welfare issues, such as disease outbreaks, food shortages, and floods.
This book summarizes a workshop on the potential contributions of remotely sensed data to land-use and land-cover change and ways to use physical, biological, temporal, and social characteristics of particular locations to support decisions about human welfare. The discussions focused on human health and food security, two aspects of human welfare in which remotely-sensed environmental conditions play a key role. Examples illustrating the possibilities for applying remote sensing for societal benefit are included throughout the report. As a result of the workshop, three themes were identified that, if fostered, could help realize the potential for the application of land remote sensing to decisions about human welfare: (1) integration of spatial data on environmental conditions derived from remote sensing with socioeconomic data; (2) communication between remote sensing scientists and decision makers to determine effective use of land remote sensing data for human welfare issues; and (3) acquisition and access to long-term environmental data and development of capacity to interpret these data.


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- Film Note : -movie_rating-
- Release Date of film : 2014-01-10
- Average rate : 5.5
- Vote Count : 63
- Societies of production : Millennium Films
- Status : Released
- Tagline :
- Duration of movie : 99
- Languages spoken : English
- Youtube Id : -youtube_id-
- Original title : The Legend of Hercules
- Movie genre : Action, Adventure,
- Kellan Lutz Character (Hercules)
- Liam McIntyre Character (Sotiris)
- Gaia Weiss Character (Hebe)
- Scott Adkins Character (King Amphitryon)
- Roxanne McKee Character (Queen Alcmene)
- Liam Garrigan Character (Iphicles)
- Jukka Hilden Character (Creon)
- Rade erbedija Character (Chiron)
- Johnathon Schaech Character (Tarak)
- Luke Newberry Character (Agamemnon)
- Kenneth Cranham Character (Lucius)
- Sarai Givaty Character (Saphirra)
The Legend of Hercules Synopsis:
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OEM Style Piston assembly. 84-06 Yamaha 485 twin. Std size
Part #: 09-813P
List Price: $91.50
Regular Price: $59.99
Sale $49.99
All components will interchange with OEM.
High performance, cast pistons closely match original equipment. Engineered for the best possible heat transfer from combustion chamber to cylinder walls.
All pistons are priced with ring(s), wrist pins and circlips
|OEM Replacement This part is aftermarket equipment designed to replace the original manufacturer's part numbers specified here. It is manufactured using high-quality materials, to the same specifications as the original part.
|Yamaha 8V0-11631-00-96, Yamaha 8DJ-11631-00-A0
|Bore (mm)
|Stroke (mm)
|Number of Cylinders
This part fits: (click the plus signs to expand)
- Yamaha (fits 59)
- PZ480A Phazer SS
- PZ480B Phazer SS
- PZ480EA Phazer SS Elec
- PZ480EB Phazer SS Electric
- PZ480EJ Phazer E
- PZ480EK Phazer
- PZ480EL Phazer Deluxe
- PZ480EM Phazer Deluxe
- PZ480EN Phazer Deluxe
- PZ480EP Phazer II LE
- PZ480ER Phazer II LE
- PZ480ES Phazer II LE
- PZ480ET Phazer II LE
- PZ480EU Phazer II LE
- PZ480EV Phazer II LE
- PZ480EW Phazer II LE
- PZ480H Phazer
- PZ480J Phazer
- PZ480K Phazer
- PZ480L Phazer
- PZ480M Phazer
- PZ480N Phazer
- PZ480P Phazer II
- PZ480R Phazer II
- PZ480S Phazer II
- PZ480SEH Phazer SE
- PZ480STA Phazer Mountain Lite
- PZ480STB Phazer Mountain Lite
- PZ480STR Phazer II ST
- PZ480STS Phazer II ST
- PZ480STT Phazer II ST
- PZ480STU Phazer II ST
- PZ480STV Phazer II ST
- PZ480STW Phazer II Mountain Lite
- PZ480T Phazer II
- PZ480U Phazer II
- PZ480V Phazer II
- PZ480W Phazer II
- Phazer 500
- Phazer 500 Deluxe
- Phazer Mountain Lite
- VT480A Venture XL
- VT480GTS Venture GT
- VT480GTT Venture GT
- VT480R Venture XL
- VT480S Venture XL
- VT480T Venture XL
- VT480TRA Venture TR
- VT480TRB Venture TR Elec
- VT480TRW Venture TR
- VT480U Venture XL
- VT480V Venture XL
- VT480W Venture XL
- Venture 500 XL
- Venture XL


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As President Obama and Mitt Romney campaigned heavily in the battleground state of Ohio on Thursday, new polls show neck-and-neck race in Colorado with both candidates tied at 48 percent; meanwhile in Nevada, the president still holds a slight advantage. NBC's Chuck Todd reports.
The race between President Barack Obama and Republican nominee Mitt Romney is locked in a dead heat in Colorado, while the president maintains a narrow edge in the other Western swing state of Nevada.
Read the full Nevada poll here (.pdf)
Obama and Romney are tied at 48 percent among likely voters in Colorado, according to the new NBC News-Wall Street Journal-Marist polls conducted this week, entirely after the third and final presidential debate. Among the broader sample of registered voters, Obama holds a 48 to 47 percent lead over Romney.
Read the full Colorado poll here (.pdf)
Justin Sullivan / Getty Images
Republican presidential candidate Mitt Romney speaks during a campaign rally at Worthington Industries on Oct. 25, 2012 in Cincinnati, Ohio.
The race for the Centennial State has tightened since mid-September – right after the Democratic convention and before the debates – when Obama led 50 percent to 45 percent.
But the president's lead has held in another important battleground state, Nevada.
Obama leads Romney, 50 to 47 percent, among likely voters in Nevada. That result is within the margin of error, but also mirrors the late September Nevada NBC/WSJ/Marist poll, when Obama was up 49 percent to 47 percent among likely voters.
Among the broader sample of registered voters, Obama's lead in Nevada expands to 51 percent to 45 percent.
"I think we're at a different point than we were in mid-September," said Lee Miringoff, director of the Marist Institute for Public Opinion, which conducted the polls. "Romney's had a better October than any of the other months in the campaign. We do see a change in his favorability. He's no longer upside down. That's leveled off. He's doing better with independent voters, closed the gender gap, and doing better with women. What that means for a place like Colorado -- it is extremely close right now, but it is clearly a state that could go either way."
Romney makes gains in Colorado
In Colorado, Obama is not hitting his mark with white voters, and is now losing suburban Denver voters as well as independents to Romney, who has also closed the gender gap versus the president. Enthusiasm among young voters has also fallen off for the president.
Men and women alike in Denver's suburbs have shifted toward Romney; a month ago, Obama led by 18 points among Denver suburban women, an advantage that closed to 3 percent in the most recent poll. Romney has expanded his lead among Denver's suburban men from 6 points last month to 13 points in this week's poll.
Pablo Martinez Monsivais / AP
President Barack Obama greets supporters on the tarmac upon his arrival on Air Force One at O'Hare International Airport in Chicago, Thursday, Oct. 25, 2012.
A month ago, Obama led with independents 50 to 39 percent, an advantage which has shrunk to a virtual draw, 46 to 45 percent. Among women, the president led in September by a whopping 14 points, 54 to 40 percent, a lead that has been halved to 7 percent (52 to 45 percent).
Obama has been able to stay even with Romney by maintaining big margins in Colorado's more liberal bastions and with strong support from Latinos, who say they support the president 63 to 34 percent. They make up a larger percentage of the electorate than 2008 and are breaking for Obama by a wider margin.
Latinos fuel Obama's Nevada edge
Nevada is slightly friendlier turf for the president; Obama won Colorado by 9 percent in 2008, and won Nevada by 12 points.
Fueling Obama's lead in the Silver State is an even larger margin over Romney among Latinos and robust early voting for the president. Romney, in turn, is aided by stronger enthusiasm by Republicans, who are helping keep the GOP nominee in the race.
Hispanics, who make up 16 percent of respondents, broke for the president, 74 to 23 percent, versus Romney.
Seventy-one percent say they have either already voted or plan to vote early. Obama leads with those who say they have already voted (53 to 45 percent) and by a wider margin with those who have not yet decided if they will vote early or on Election Day (53 to 38 percent).
How crucial is the Latino vote in these two states to Obama?
"In a close race, every group makes a difference," Miringoff said, but this group really makes a difference. It's keeping him in the contest in these states."
The polls were conducted Oct. 23 to 24. The Nevada poll has a margin of error of +/- 3 percent among likely voters. The Colorado poll has a margin of error of +/- 2.9 percent.
Reuters, Getty Images
In the final push in the 2012 presidential election, candidates Mitt Romney and Barack Obama make their last appeals to voters.


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The Weakening of the Safe Water Drinking Act
In The Drink: About the Report
All information presented in this report was based upon information contained in the EPA's Federal Reporting Data System (FRDS), a database maintained by EPA. The Environmental Working Group obtained the FRDS database, which contains over 300,000 records, via the Freedom of Information Act.
EPA maintains the FRDS database as a repository of compliance information on the Safe Drinking Water Act. States are responsible for entering all violation information into the database, and correcting any data errors.
The EPA FRDS data presented here significantly underestimate the number of systems out of compliance with the Act's health standards. First, many water utilities are not performing required testing, and thus are not detecting and reporting drinking water problems. In 1993-94, 52 million people, 20% of the nation's population, were served water by a utility that violated a SDWA monitoring requirement.
Second, many states are failing to report drinking water systems that are in violation of federal health standards. A 1990 GAO investigation found numerous instances where violations of the SDWA known to states were not reported as violations to EPA (GAO 1990). A 1988 investigation by EPA's Inspector General reported similar findings (EPA Inspector General 1988). And in 1992-93, 18 states reported no violations of chemical or radiological MCL standards (NRDC 1994). This is not because there is perfect compliance with standards in these states, but because these states are failing to report violations. The GAO concluded that, although there were a few instances of over reporting in EPA data, in the vast majority of cases many violations went unreported. Because of this rampant under reporting, the fact that a water system does not appear to have any reported violations should not necessarily be taken to mean that the system has not exceeded EPA health standards.
The following information from FRDS was used in this report.
- Inventory information on each of the 185,000 drinking water systems in the United States, including names, locations, and population served.
- Records of 235,000 violations of the Safe Drinking Water Act's Maximum Contaminant Level standards, violations of Surface Water Treatment Rule treatment technique requirements and SDWA monitoring, reporting, and notification requirements (which direct water systems to test the water for chemicals and microorganisms to ensure safety and inform the public of any problems).
- Lead milestone data, containing 12,000 records of water system activity as part of EPA's Lead and Copper Rule. Included in this database is information pertaining to whether water systems have exceeded EPA's Lead Action Level, an indication of increased health risks from lead.


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Song Plantable Favor Tag
Say thank you to your wedding guests with our eco-friendly bridal favor tags. Made from post-consumer waste and embedded with high-grade, pure North American wildflower seed, these seed paper favor tags will give your wedding favors the perfect final touch. When your guests plant the seed paper, it recycles itself into wildflowers.
See our matching plantable wedding invitations, reply cards and our plantable thank you cards.
Ribbon not included.
Size: 2 x 3 1/2 inches
Shipping: This product ships in 3 business days from date proof is approved.
Wildflower Seed Mix: Grows a blend of colorful wildflowers including Bird's Eye, Clarkia, Black Eyed Susan, Sweet Alyssum, Catchfly and Snapdragon.
Tri-Herb Blend (Optional): Basil, Parsley & Oregano.
Planting Instructions
Plant seed paper under 1/8" of soil. Water thoroughly. Place in a sunny corner and keep moist during germination.
There are no reviews for this product.


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westonbrands.com has temporarily stopped taking orders until further notice. We are sorry for any inconvenience. Should you require further assistance, please contact Customer Service.
We are currently upgrading our distribution centers to better serve our customers. Please shop your preferred retailer to purchase Weston products during this time.
To be notified once online ordering is again available, please submit your email address.
Replacement part for Weston 5 and 11 lb. Vertical Sausage Stuffers (73-0501-W & 73-1101-W)


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Ox (Feat. Jim Jones) - Killa Squad / Hold The Bottles Up [Label Submitted][Fixed]
" In studio footage of L-Gang Ent. general Ox & the Capo Jim Jones in the studio laying down a club banger produced by Shatek and NY Knick Wilson Chandler stops by to show support. Check the impromptu Ox L-Gang Killa Squad video shot by Shatek midway thru the session. Follow TWITTER.COM/OXLGANG TWITTER.COM/KINGSMIJ TWITTER.COM/SHATEK"
Please click the "Report" button below if the video on this page is not working properly.
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Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence® Control siRNA (Unconjugated) #6568 (-), SignalSilence® PAK2 siRNA I (+) or SignalSilence® PAK2 siRNA II #6507 (+), using PAK2 (C17A10) Rabbit mAb #2615 and α-Tubulin (11H10) Rabbit mAb #2125. The PAK2 (C17A10) Rabbit mAb confirms silencing of PAK2 expression, while the α-Tubulin (11H10) Rabbit mAb is used as a loading control.
Product Information
CST recommends transfection with 100 nM PAK2 siRNA I 48 to 72 hours prior to cell lysis. For transfection procedure, follow protocol provided by the transfection reagent manufacturer. Please feel free to contact CST with any questions on use.
Each vial contains the equivalent of 100 transfections, which corresponds to a final siRNA concentration of 100 nM per transfection in a 24-well plate with a total volume of 300 μl per well.
SignalSilence® siRNA is supplied in RNAse-free water. Aliquot and store at -20ºC.
SignalSilence® PAK2 siRNA I from Cell Signaling Technology (CST) allows the researcher to specifically inhibit PAK2 expression using RNA interference, a method whereby gene expression can be selectively silenced through the delivery of double stranded RNA molecules into the cell. All SignalSilence® siRNA products from CST are rigorously tested in-house and have been shown to reduce target protein expression by western analysis.
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, control of phagocyte NADPH oxidase, and growth factor-induced neurite outgrowth (1,2). Several mechanisms that induce PAK activity have been reported. Binding of Rac/Cdc42 to the CRIB (or PBD) domain near the amino terminus of PAK causes autophosphorylation and conformational changes in PAK (1). Phosphorylation of PAK1 at Thr423 by PDK induces activation of PAK1 (3). Several autophosphorylation sites have been identified, including Ser199 and Ser204 of PAK1 and Ser192 and Ser197 of PAK2 (4,5). Because the autophosphorylation sites are located in the amino-terminal inhibitory domain, it has been hypothesized that modification in this region prevents the kinase from reverting to an inactive conformation (6). Research indicates that phosphorylation at Ser144 of PAK1 or Ser139 of PAK3 (located in the kinase inhibitory domain) affects kinase activity (7). Phosphorylation at Ser21 of PAK1 or Ser20 of PAK2 regulates binding with the adaptor protein Nck (8). PAK4, PAK5, and PAK6 have lower sequence similarity with PAK1-3 in the amino-terminal regulatory region (9). Phosphorylation at Ser474 of PAK4, a site analogous to Thr423 of PAK1, may play a pivotal role in regulating the activity and function of PAK4 (10).
Explore pathways + proteins related to this product.
UniProt ID: Q13177
Entrez-Gene Id: 5062
|Product #
|300 µl (3 nmol)
|$ 270


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These fabric balls are the perfect handmade baby gift, multicolored, soft and round…..what's not to love! Sewers of all levels will have fun making these toys that will be worthy of passing down from generation to generation.
Enjoy! –Page
We recommend 1/4 yard of each fabric to leave room for error.
These are the fabric I used:
Large Ball
- Nani Iro White Tossed Flowers
- Yuwa Honeycomb in Red
- Kaffe Fassett Shot Cotton in True Cobalt
- Carolina Chambray in Royal
Medium Ball
- Nani Iro Pink Blooms
- Yuwa Honeycomb in Pink
- Yuwa Honeycomb in Aqua
- Net of Jewels in Carnelian
Small Ball
- Nani Iro White Scattered Dots
- Robert Kaufman Kona Cotton in Daffodil
- Kaffe Fassett Shot Cotton in Persimmon
- Yuwa Honeycomb in Blue
Other Materials
- Cotton Stuffing
- Cotton Thread that blends with chosen fabrics – We used #1040, #5910, and #6800
- Fabric scissors
- Applique needle
The Pattern
Finished Measurements
- Small ball: approximately 5-inches diameter
- Medium ball: approximately 7-inches diameter
- Large ball: approximately 9-inches diameter
Download this template for the small and medium balls, and this template for the large ball.
You will need to cut eight fabric pieces total to make each ball. We used two each of four different fabrics for ours.
Fold fabric in half by lining up the selvages so that you can cut two pieces at a time. Lay template on the fabric and trace with a pencil. Cut the fabric on the drawn line. Repeat this process with the remaining fabrics so you have eight pieces total.
Pin the cut pieces in pairs right sides together, carefully aligning the points and edges.
Chain-piece the pairs, sewing past the points at each end using a 1/4-inch seam allowance. You don't need to backstitch because you'll reinforce these seams when sewing the pairs together. Be sure to make smooth curves as you are sewing so that the ball will be nicely rounded. After chain-piecing, carefully cut the threads between each pair. Press the seams to the side of the darker fabric.
Pair the pieces once more, aligning their cut edges with right sides together and pin them together. Sew them together to create two half-sphere shapes with four pieces each. Press seams to the side of the darker fabric.
Turn one half-sphere right side out, and tuck it inside the other half-sphere, with right sides together. Align the points and edges, and pin the two pieces together. You'll want to begin one of your seams 1- inch from the point to leave an opening for you to turn the ball right side out and to stuff it. Take care not to sew over the nice points you've made at the ends when stitching the previous seams. Your top seam should just intersect the point where the previous seams meet.
Turn the ball right side out through the opening, and stuff it firmly, making a spherical ball.
Fold and finger-press the edges of the opening 1/4 inch to the inside to create a clean edge. Using a blindstitch, carefully hand-sew the opening closed, stitching just inside the fold for an invisible seam.
Cut two circles for each ball to sew at each end. We recommend using the darkest solid fabric for this since it is a way to cover the part where all the seams come together which isn't always perfect. We cut a 2 -inch circle for the large ball, a 1 3/4-inch circle for the medium ball, and a 1 1/2-inch circle for the small ball. Fold and iron the edges of the circle approximately 1/8-inch. Hand-sew the circles on each end of the ball using a hand stitch.
If the balls have gotten a bit misshapen while sewing on the circles, manipulate them back into a nice spherical shape and you're good to go!


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Former Hialeah Mayor Julio Robaina and his wife Raiza made their first appearance in court Friday after turning themselves in to federal custody to face tax fraud charges.
During the afternoon hearing at the federal courthouse in Miami, a judge set Julio Robaina's bond at $250,000. Raiza Robaina's bond was set at $100,000. Both will have to surrender their passports and will be arraigned next Friday, the judge ruled.
"Obviously, yesterday was not what we expected. We did not expect the IRS to move forward on this case that soon we will prove has no merits," Robaina said outside the federal courthouse in Miami with his wife by his side. "We're hoping and we will have our day in court soon, and we will prove our innocence."
He added: "Today is not a day to talk about the merits of the case, but there will be a day very soon where we will prove there are no merits to the IRS' case."
He gave this thanks to the supporters and friends who have emailed, called and sent text messages.
The Robainas are accused of conspiring to evade their taxes, creating false returns, making false statements to federal agents and failing to report their true income to the IRS.
A 10-page indictment released Thursday claims the couple, who own a loan company, made six-figure transactions between 2005-2007 but reported small five-figure losses. Over those two years, officials allege the Robainas' taxable personal income was falsely understated, while Mr. Robaina's business tax forms showed inflated losses.
The allegations were uncovered after convicted Ponzi-schemer and Robaina acquaintance, Luis Felipe Perez, helped investigators, his attorney said in a statement to NBC 6. The information provided by Perez linked Robaina to a loan operation that paid him off with interest in cash, the attorney said.
"[Perez] turned over records showing payments to Mayor Robaina as well as others at very high interest rates. The records reflected monthly payments of the interest, half by check and half by cash. Additionally, [Perez] provided testimony and witnesses who would make the cash payments..." said Alvin Entin, Perez's attorney.
Through their attorney, the Robainas have denied the allegations.
"Both Mr. and Mrs. Robaina are disappointed by the turn of events. But, at the same time, they are very confident and look forward to their day in court," said David Garvin, the couple's attorney.
Robaina, 48, served as Hialeah's mayor from 2005-2011 before resigning to run for Mayor of Miami-Dade, an election he lost to Carlos Gimenez.More Local Stories:


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No, not me. Though I am fahbulous.
Mike Rowe from the show Dirty Jobs. Apparently, he's getting a lot of speaking jobs lately talking about "on the "changing face of the proletariat vis-à-vis the modern-day work ethic and the digital divide", according to the New York Times and he has a website called Mike Rowe Works, which helps people find technical and trade jobs and education.
General Link: http://www.mikeroweworks.com/noflash.html
Jobs Link: http://www.mikeroweworks.com/job-site/
It's a well rounded site and like most truly funny people, Mike Rowe is an intelligent and thoughtful spokesperson for the cause of worker education and job seeking. Well, from what I can tell from the article I've been reading.
Librarians help people find work, Mike Rowe helps people find work. Librarians help provide training and tools for people to improve themselves with, so does Mike Rowe. Mike Rowe is hot and really funny. Librarians are…er…we're sometimes hot and usually pretty funny.
Just my suggestion. Please consider it if your state or national library organization needs a speaker. There's potential for great synergy I think.


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Hand Knits in Action
by exercisebeforeknitting
Thank you for all of the sweet comments about my DROPS cardigan! In spite of a few quibbles with it, I am quite pleased with the outcome! And the yarn! Oh, the yarn. You all need some Queensland Kathmandu DK Tweed. Did I mention that it's the same as Jo Sharp Silkroad DK Tweed? I suspected as much but a trip to my LYS confirmed it: the Jo Sharp yarn color numbers are exactly the same as the Queensland color numbers. Coincidence? I doubt it.
I thought I'd distract you this morning with some hand knits in action:
This Bea Ellis hat and Lamb's Pride scarf I made Aaron are the only things I've knit him that see reliable wear. To be fair, they're the only things I've knit him that are very nice. You should see this sweater I made him pre-blog – it's positively hideous. In any case, his gloves aren't very warm and I thought I would make him a pair of thrummed mittens for nighttime dog walking. He's long maintained that mittens are far inferior to gloves in terms of dexterity but then again, dog walking requires little of that. And certainly, there will be very little range of motion in these babies. I got the idea from Jenna and then Pam had to go and cast on for some and, well, here you go.
In a rash of vacation startitis, I also cast on a few more projects. At least the rest of you can blame holiday knitting. I swore off that this year so I have no excuse. Below, a top-down raglan in Beaverslide wool and the second Drunken Bee to match the sock Stella so ably knit for me. I keep casting on for more because none of these are (yet) purse projects. The sweater was ideal until it grew too big to fit in the purse. The sock was great for the ribbing but I haven't yet memorized the pattern and so I can't knit and do anything else. The mitten pattern is easy to memorize and nice and portable but the thrums are decidedly not easily transportable.
I'm not even going to add these to my Ravelry project list until they're done because I don't really want to see my WIP list go up. What denial, eh?


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- This event has passed.
Daytime Drop in Support Group (Wed)
Wednesday 11th Dec, 2019, 10:30 am, 10:30 am - 12:30 pm
|Recurring Event (See all)
An event every week that begins at 10:30 am on Wednesday, repeating until Wednesday 18th Dec, 2019, 12:00 am
Drop in morning support sessions are held in Television House on a Wednesday and Friday from 10.30am till 12.30pm term time only.
Everybody is welcome, with or without a formal diagnosis of ADHD, ASD or Asperger Syndrome.
The session offers a chance to meet other parents in a similar situation. There are family support workers available to discuss any support and help needed in a confidential environment. This could be a good place to start if you're new to ADHD or ASD, want to find out what our centre offers, or if you just want to talk to someone who understands.
Crèche available. The crèche is free, however donations are welcome.


text:
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text:
Beginning PL/SQL: From Novice to Professional
Donald Bales
立即出貨(限量) (庫存=3)
Get started with PL/SQL, the built-in language that every Oracle developer and database administrator must know, in Beginning PL/SQL, a fast-paced and example-filled tutorial. Learn from author Don Bales?extensive experience to discover the most commonly used aspects of PL/SQL without wasting time with obscure and obsolete features.
Author Don Bales takes his 20+ years of experience and a wealth of statistics he's gathered on PL/SQL usage over those years and applies the 80/20 rule ?cover whats most needed and used by PL/SQL professionals and avoid whats not necessary! The result is a book that covers all the key features of PL/SQL without wasting your time discussing esoteric and obsolete parts of the language. Learn what really matters, so that you can get to work feeling confident with what you know about PL/SQL.
- Discover the 20% of PL/SQL that gives you 80% of the bangkey topics covered include variables and datatypes, executing statements, working with cursors, real-world objects, debugging, testing, and more.
- Learn how to write production-level, object-oriented PL/SQLyoull explore relational PL/SQL, but unlike most other books on the subject, Don Bales emphasizes the use of PL/SQLs object-oriented features as well.
- Work through real examples of using of PL/SQLyoull learn PL/SQL by applying it to real-world business problems, not by heavy theory.
How important SQL is in PL/SQL How to use PL/SQL in both a relational and object-relational setting How to create maintainable, modular, and reusable PL/SQL program units The importance of testing as you go, and of building a permanent test plan for each module The importance of building debugging capabilities into your code and building a permanent debug facility for each module The importance of documenting as you go, and in the process building a permanent documentation set for your reusable modules How to apply modular PL/SQL to solve real-world problems


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Oh, my goodness, do I pin!
I have my own little Pumpkinbear Pinterest land right here:
On it you can see my seemingly millions of boards, all neurotically categorized.
I have board for projects organized by theme:
I have holiday boards, with projects and recipes and crafts and homeschool unit studies:
I have recipe boards, some for recipes that I want to make--
--and some for recipes that I make all the time:
I have boards for projects that are imminent to-dos:
I have idea boards:
And those aren't even ALL my boards.
Also, because I'm a big nerd with a library science degree, I curate my boards, which means that I go through them, perfect the links, cross-reference them to relevant boards, and edit the commentary to be descriptive, accurate, and informative.
I can't believe how useful Pinterest has been for me. I use it to brainstorm for homeschool activities within the girls' areas of interest, and for holiday projects and kid crafts. I try new recipes from Pinterest (I've got these cranberry sauce meatballs in the crock pot right now!), and if I like them, then I move them to my Favorite Family Foods pinboard so that I can find them again easily.
Didn't people used to use file cabinets for stuff like that? Geez, wasn't that a fire hazard?


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This Audio CD represents Volume 3 in Gītasaṁskṛtam (AP103) and Geyasaṁskṛtam (AP102) series. A total of 8 songs are rendered by incorporating various musical genres set to contemporary beats and music style. Songs sung by Rajesh Krishnan and Ramya Vasisht
Songs rendered in this album (various composers; music by Kiran Bhat)
Alternatively you can purchase and download the audio directly from google play store by clicking this link: Pathika (पथिक)
(Note: You will be leaving this samskritabharatiusa bookstore site and entering google playstore. You will require a google account to complete your purchase.)
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Copyright © 2017 Samskrita Bharati USA.