text:
Once again, University of California pole vaulter Allison Stokke is being hunted by the wandering trolls of the internet, thanks to the emergence of new photos featuring the athletic teenager wearing her required sporting uniform and holding a giant pole .Her dad, the chronically annoyed and litigious Allan Stokke, is most likely taking this latest outbreak with the same degree of fatherly aghast which compelled him to try to figure out some way he could file suit against every single person who used the internet the last time. (It's understandable, but be reasonable, old man.)
For now, according to Busted Coverage, Cal is taking a stand by pulling all visual evidence of Ms. Stokke off of its website to protect its star freshman from the millions of creepy men looking for a photo of her newly muscled physique.
Cal's message: You won't be masturbating to Allison on our bandwidth. Go elsewhere with your unwieldy erection, you pervert.
Allison Stokke Photos Pulled From Cal Track Site [Busted Coverage]
Allison Stokke [Cal Bears]


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It's pretty rare that we invite someone back to speak again at Tamper Tantrum, not because the speakers aren't amazing, but because we want to provide a diverse range of opinions and thoughts from different people across the industry. Every now and then, however, the stars align and we find ourselves with a repeat speaker. In truth, this makes us a little nervous: will they be able to deliver something just as good, if not better, than their original presentation? Will it still be as thought-provoking and inspiring?
James Hoffmann has spoken at Tamper Tantrum Live twice, co-hosted our Asia Tour, and was a massive part of Episode the 19th, announcing the newly formed Euroguild (Barista Guild of Europe). He had already outdone his Dublin 2011 talk with his Birmingham 2014 talk, but could he do it again?
It is with great pleasure that we present to you his unprecedented THIRD talk for Tamper Tantrum, recorded in Taipei, Taiwan on our Asia tour last year. An annoyingly clever presentation, James speaks here about the importance of telling stories in the coffee industry and how we're doing it all wrong. And, of course, in honour of his incredible contribution to Tamper Tantrum over the years, we hereby declare today to be #jimsevenday.
Listen here: http://tampertantrumaudio.podbean.com/e ... 433774902/
Watch here: http://www.tampertantrum.com/?p=893&preview=true

subset: commoncrawl


text:
Gradle / subprojects / language-scala
Change all subprojects to use 'implementation' dependencies
This includes:
- All projects now explicitly declare all dependencies to other
subprojects. This makes issues more visible, guards for accidental
addition of new dependencies, and leaks much less transitive
dependencies on the compile classpathes.
- All usages of 'runtime' to declare dependencies have been replaced
with 'runtimeOnly'
- All projects are now `java-library` (and declare this explicitly)
- Most remaining Groovy scripts are translated to Kotlin
- The old 'compile' and 'runtime' configurations are not
configured/created anymore for the 'testFixture' and 'integTest'
source sets.
- Some obsolete dependencies (see previous commits) are removed
- 'api' is used scarcely on purpose as the current project structure is
not well designed for this. The projects contain code for several
concerns of the build tool and thus putting complete projects on the
API of others exposes too much. They should be split up along
functional concerns first.
Make more subprojects use Java 8 and remove redundant module types (#9447)


text:
Sunday, April 27, 2008
The Book: Finishing My Ultimate Marathon
Where this book took me:
+ To the Giant Sequoias to research their secrets of immortality;
+ To the Hillerich & Bradsby/Louisville Slugger Museum in KY;
+ To the Joshua Tree forest just like U2
+ To the finish line of the New York City Marathon;
+ To the Hershey Chocolate World factory tour;
+ To Route 66 and the history of the greatest teamwork lesson ever
+ To Fenway Park and New England's fabulous fall color show
+ To native lore and love at little Tucumcari, New Mexico
+ To Miami's Fifth Street Gym and an amazing phone call from Muhammad Ali
+ To Central Park and its 26,000 glorious trees in every season
+ To the shores of Lake Erie skipping stones
+ To the original streets of Evansville, Indiana, and its libraries/museum
+ To countless leadership books and on a philosophical journey
+ And, thanks to my special contributors, places all around the globe
During the course of this work, I had to change a sentence about the cost of a postage stamp not once, but twice. It was 37 cents when I first entered the sentence in 2004, then 39, and now 41. Less than one hour into my 2/1/03 drive West that began everything, I heard on the radio as the Space Shuttle Columbia broke apart during re-entry; by the end of the work, I was honored to be friends with a NASA astronaut who spent a long time on the International Space Station. During the course of this work, I went from overweight smoker to whom things happened to a marathoner making things happen.
Stay tuned! Nothing is handed to you. If you believe in yourself and follow your passion, I believe good things will happen. Maybe this will be a seminal work in literary history! Maybe it will be my great white elephant and I have just wasted half a decade! That is the thrill in it all. Just have a goal, enter the race, make things happen, and live it. Start and Finish. I have some more work to do now!
Sunday, April 6, 2008
St. Louis Marathon: Thick Wit It!
6:08 finish at the 2007 ING New York City Marathon last November, my injury-plagued 26.2 mile debut.
5:21 finish today at the 2008 St. Louis Marathon on the hilliest/toughest course I know.
4:?? at the 2008 ING New York City Marathon on Nov. 2.
I am going to hire a research firm to see if they can detect a trend...
Loving every moment right now, have incredible pics of my weekend with my awesome crew including my 20-year-old son Matt and his girlfriend Amanda, my 16-year-old son Ben and his girlfriend Erica, and my 14-year-old son Josh. They were waiting at the finish line for me with cowbells and signs including "HEART OF A CHAMPION". They were my awesome 21.2 Pit Crew!
This was my second marathon, so this is my second marathon post. Here are the pictures and the words.
With my 14-year-old Josh:
After picking up my registration stuff at the Marathon Expo. The Arch says it all...
Ben (16) with Winthorpe (now 11):
Ben and Erica below. He swiped the Sleep Number gift from my Expo bag -- a sleep mask!
The crew:
I am so proud of my boys, and nothing new when Matt opened a letter waiting for him at the house. It was welcoming him to a national scholastic excellence organization after he made the Dean's List this semester at the University of Missouri's School of Finance. I was so proud when he opened it. He came over just for this race and had two tests on Monday and one on Tuesday, so I know it was a big sacrifice for him, and that's how much we all love each other. I also got to see him study for Accounting and Marketing tests and am blown away by how organized he is, with his meticulous notes printed out and put into a binder that he studies, etc. So far beyond what I was doing in college. Love my guys.
Here is my temporary tattoo with splits for a 5 Hour Pace. This was AMAZING. I got it at the expo. Better than a pace bracelet. I repeatedly looked down at my forearm after Mile 20, when I was on my own, to gauge how well I was keeping up with my pace.
My motel room the night before. I decided to go with the orange look:
We had our own Pasta Party at the boys' house. I made fettuccini with alfredo sauce and bowtie pasta with red sauce, and everyone mixed and matched. Josh gave me the lowdown on Hakeem tha Dream and why I had to download THICK WIT IT from iTunes, so it was a powersong now, too. Here it is:
The pasta party was better than the official Pasta Party downtown. I went back to my motel room and got to sleep at 12:40 a.m.
Miles 1-16
I slept 4 hours, waking up at 4:40. I got down to the Union Station area at 6, and the race started at 7. I checked my bag with everyone else inside City Hall, an amazing scene of runners. Then I hit the portapotty and looked for Molly. She had been at the table at the Expo the day before, and I had signed up to be part of the 5 Hour Pace Group that she would be leading.
There were maybe 20 of us in that group. We started out great. It was an indescribably beautiful St. Louis spring day, as Mizzouri Governor Matt Blount -- who was running on a marathon relay team -- pronounced to runners. We ran toward the Arch and the sunrise, just gorgeous. Then we hung a right and proceeded South all the way to the Anheuser-Busch Brewery. If you've ever been to St. Louis, you know what an institution this is. The huge BUDWEISER sign at the top tells you where the King of Beers is based. This is it. The greatest beer by sales and Super Bowl commercials. I will get way ahead of myself here and let you know that 200 meters before the finish, I was handed a beer by volunteers, who said, "Don't worry, you will be fine. Drink it."
We then circled back north toward Market Street, and then came a long trek West. The course went through many iconic St. Louis areas, including the Purina HQ, Barnes Jewish Hospital, Washington University, and more. There were cowbells everywhere, and I had bought two for my crew. They were selling them at the Expo, at a booth called "26.2 Pit Crew." People: You HAVE to get some 26.2 Pit Crew stuff at your next Expo. Everytime I heard a cowbell, I remembered the Saturday Night Live skit and yelled, "More cowbell!" I cheered for other runners. I shouted repeatedly: "I LOVE HILLS!!!!" I was total energy man. That was for the first 15-16 miles, and that even included going through Forest Park, a 3 1/2-mile stretch that I had absolutely feared leading up to this event.
Here is a picture during the first half. That's Molly on the right. You can also get a good view of my pace tattoo! I look like hell, and I had halfway to go! But damn I felt great.
Miles 16-26
Molly said at one point, "I'm not letting you go." Our pace group had winnowed down to a handful halfway through. She was a couple of minutes ahead, and I had visions of a 4:58 or so. I was so psyched. She was doing a great job, and I appreciate pace runners because her PR is like 3:20. I am sorry to say that I lost sight of Molly and the rest of them once we got into Clayton. That is where the bubble burst on my 5 Hour time. That is where I realized that the second half of this marathon was the hilliest one I have heard about anywhere.
Once we were at the extreme edge of Clayton, I was the farthest away from the finish line at any point on the course, and I stared at this LONG and STEADY incline ahead of me on Delmar Boulevard, and my courage was tested right then and there. I tried to run. I got lightheaded. I stopped briefly at a med tent, and they let me sit there for a few minutes, gave me Gatorade, I stood up, lubed with vaseline on chest and thighs, tried to run, then got wicked right calf cramping. That was a hard mile or two of pure survival. I tried to run but it was heavy walk-run-walk. I lost 10 minutes in that area of the course.
It never got a whole lot easier. We ran through University City. I was in a battle of wills at that point. Spectators were few and far between. An occasional band. It was the opposite of the NYC Marathon with its 2 million spectators. After I lost the pace group, it was me against myself. Strike that: It was me supporting myself. I stayed positive.
Others have disagreed with me, but I have now said after both of my first two marathons that I think the term THE WALL is bullshit. The wall has nothing to do with it. I think it is a cop-out, even. It is about training, about building up quads, etc. My arms were getting tired, something I thought of often. I needed to do more arm work. If you are a positive person, there is no such thing as a wall.
The fact that I was battling had nothing to do with a wall. The hills were testing my leg power. I never had any doubt that I would get there, and my goal was seeing my kids at the finish line. I was thinking about that. I was thinking about what dance I should do across the finish line. I listened to my iPod for the back half but not the front half. I passed and was passed by and passed and was passed by various strangers who I gradually got to know and chat with. It was a battle of hills and a battle of wills. Guess what, I made it.
My Achilles tendon was perfect. The last 3 miles were straight uphill, staring at the Arch in the distance the whole way. Forever. I got to Mile 26, and all I could think of was seeing Matt, Ben and Josh. Then I did. First I saw Matt, then Josh, holding up the big white "HEART OF A CHAMPION" sign. Then I saw Amanda, then Ben with Erica. They were making cowbell music. Then I took a slight left turn that led us into a 20-yard run through the Finishing corral.
For that whole stretch, I danced to Nelly's Heart of a Champion. I overdid it big time just because. The announcer said, "And here comes Mark Newman, from New York City!" THAT IMPRESSED ME! What other marathon does that for just some participant, spotting your bib number and looking you up and giving you that personal touch? As they said my name, I am jumping, pumping my fists in the air, dancing, hopping, doing Nelly right since he's a St. Louis guy. I was "S-T-L Derrty." I was a soldja, I thought I toldja. I just ran 26.2 miles. I literally fly across the chip mat, hoping my chip was not too high from the mat to record my time. They put a medal around me, I reunited with my crew, life was great.
There is a funny story about one of the photographers toward the end. He stood in front of me and waited until the last split second to jump out of the way. I thought I was going to run him over, I swear. It was like I was Lance Armstrong and he was the motorcycle-cam right in front of him. Dude, I am not that fast!!! I'll bet you that will be an awesome running photo, though. If you like seeing death warmed over.
Here is what I consumed during the course of my second marathon:
I had a banana and a few bites of bread two hours before the race. I had a bottled water and a bottled clear sport drink. Sipped from each up until the race. Portapotty 15 minutes before start.
At midnight before the race, I bought a bag of pretzels and saran wrap at a Walgreen's. I was going to crunch them up and wrap them and then safety-pin that to the side of my shorts like a woman taught me at the Nike Half last August, but it was too bulky. So I just crushed a bunch and stuffed them into my left pocket. I munched on those throughout the race for SALT.
I also brought five little salt packets with me, the typical kind at a deli. They were in my right pocket. Before the race I broke one open onto my tongue and washed it down with water. I used them all up during the race. So between those and pretzels I was covered.
I was hydrated perfectly, and I had water and Gatorade at each available stop -- in moderation.
I took GU at miles 7, 14, 19 and 23. I might have even snuck one in somewhere else on the back half, as they were distributed at miles 14 and 23.
We took two cars back home, and Matt drove my rental SUV as I stretched out in the back and felt awesome.
I took an ice bath at the motel after dropping off the boys. I would appreciate it if someone can tell me how to really get through an ice bath. This time I lasted a little bit longer but it was quick. The first time I got in, I lasted one complete minute, counting every second to 60. Then I jumped out and the pain seared my legs. After a couple of minutes, I got back in. I lasted 20 seconds that time. So total 80 seconds. How do you last 5-10 minutes like they recommend? All I know is, it worked. It makes the soreness/inflammation less severe in recovery, so the following week is not as miserable. I noticed it right away.
Back at the boys' house, I played basketball with my guys. "How are you running, Dad?" Josh asked me. I didn't even know. I ran after loose balls. I tried to dunk on a goal dropped to 9 feet. I was loving life. We spent another great night together, and then I said goodbye to my dudes as Matt/Amanda headed back to college late that night and I went back to my motel for a Monday flight.
Next up for me, besides being the best I can be and even better at my awesome job in Major League Baseball, is putting together the proposal that is going to make my currently 255-page book manuscript an international best seller in every language and then screenplays and then me sailing around the world and living the largest life a man ever lived and being remembered. You can do anything. Just proved it again! You are whatever you think you are, you will be whatever you think you can be.
There were many times during these 26.2 miles when I looked down at my legs moving, and I thought to myself: How am I doing this? I never knew I could. There was a long and tortuous climb up Delmar Boulevard coming back from Clayton, and not only was the hill killing me, there was that calf cramp. Then the insides of both thighs just started doing something weird, twitching uncontrollably. I thought: What's next? On that long stretch, I kept trying to put one leg in front of the other, walking, running, trying to run more, and eventually you are just continuing to run and you get back into a zone for a while and you aren't really sure how your body keeps answering the call...but it does.
I love running. I am a multiple-marathoner now.


text:
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A comprehensive guide is designed to provide readers with a thorough roadmap of the job-search process, from the initial self-assessment and goal-setting stage to the application and interview phase and beyond. The guide offers a wealth of information, insight, and expert advice in a concise, easy-to-digest format designed for both first-time job hunters and experienced professionals who find themselves back in the job market.
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Mike Brown Fired From The Lakers After 1-4 Start!
"Antonio Davis talks about the Lakers firing Mike Brown, potential candidates and what to expect moving forward." - ESPN
Please click the "Report" button below if the video on this page is not working properly.
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Adult Protective Services (APS)investigates reports of abuse, neglect and exploitation of adults aged 60 and over and incapacitated adults over 18 years of age. APS provides services when persons are found to be in need of protective services. APS seeks to achieve:
Minimal disruption of lifestyle and least-restrictive care
For questions on how to report to APS or suspected abuse to the elderly or adults with disability, contact the Department Virginia Department of Social Services 24-hour, toll-free Adult Protective Services hotline at 1-888-832-3858.
Adult Services
The Adult Services Program assists elderly individuals or other adults who have an impairment and need services or support to enhance self-sufficiency and improve their quality of life. Services offered may include:
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These services are provided by
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and are designed to help adults remain as independent as possible, preferably in their own home. The goal is to strengthen appropriate family and social supports and reduce the need for institutional placement.
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text:
Start dynamic personal coaching on your wrist with on-screen guidance for every move and routines that adapt based on your feedback.
Start dynamic personal coaching on your wrist with on-screen guidance for every move and routines that adapt based on your feedback.
Store and play more than 300 songs on your watch – plus download your own or curated playlists from Deezer.**
See pace, distance and other key stats on display, while recording elevation climbed, split times and a map of your route.
Get continuous, automatic, wrist-based heart rate and simplified heart rate zones. Learn more.
Wear your watch in the pool or rain and use it to track swimming workouts with stats like lap counting, duration and calories burned.
Battery life of five days and up to 10 hours when using GPS, so you can track day to night without charging.*
Get instant access to important information like weather or sports updates and popular apps like Strava.
With a built-in NFC chip, you can use your credit and debit cards on the go, in any place that accepts contactless payments.
Track specific workouts in modes like Run, Bike or Weights to see real-time stats on screen and get post-workout summaries.
Automatically record selected exercises like running, biking and more, and see them saved in the Fitbit app.
Track steps, heart rate, distance, calories burned, floors climbed, active minutes, hourly activity and stationary time.
See call, text or calendar notifications on screen and get push notifications from your favourite apps. Available when your phone is nearby.
See your time spent in light, deep and REM sleep stages and get personalised insights to help you improve. Learn more.
Use the quick release button to change your accessory bands to styles in leather and more.
Sync stats wirelessly and automatically to computers and over 200 leading iOS, Android and Windows devices.
*Battery life and charge cycles vary with use, settings and other factors; actual results will vary. Smartphone notifications are unavailable on Windows devices.
**Deezer paid subscription is required.
Fits wrists 140 mm - 170 mm in circumference
Fits wrists 170 mm - 206 mm in circumference
Screen Size 29.23 mm x 21.0 mm
Width 35.99 mm diagonal
Resolution 348 x 250
21.0 mm
29.232 mm
Fitbit Ionic has a battery life of over 4 days with a GPS battery life up to 10 hours. Battery life and charge cycles vary with use, settings and other factors; actual results will vary. We recommend charging Fitbit Ionic every few days to ensure that you are always tracking.
Fitbit Ionic is water resistant to 50 metres. After swimming or getting the band wet, we recommend drying the band because, as with any wearable device, it's best for your skin if the band is clean and dry. We do not recommend wearing Ionic in a hot tub or sauna. See www.fitbit.com/productcare for more details.
If the band gets wet or if you sweat in it, remove and completely dry it before putting it back on. Give your wrist a rest by taking the band off every now and then. Learn more.
The Fitbit Ionic classic band is made of a flexible, durable elastomer material similar to that used in many sports watches, and includes an aluminium watch case and buckle.
Like all heart rate tracking technologies, accuracy is affected by physiology, location of device and different movements. Learn more about wearing during workouts.
Fitbit Ionic syncs automatically and wirelessly to computers and over 200 leading iOS, Android and Windows devices using Bluetooth LE wireless technology.
Syncing requires Bluetooth LE and Internet connection. Windows 10 computers that do not have Bluetooth LE will need a wireless sync dongle in order to sync.


text:
Wood is the new black. Maybe. We're not sure how cool wood is to be honest, but we can tell you we're not hating on Balolo's Wooden Cover for the Playstation 4. It's made from a 0.7mm thin layer of actual wood, and you have the option of buying the cover and applying it yourself, or ordering a PS4 from the company with the cover already applied. You have a choice between walnut, bamboo, 'zebra', and cherry wood, and the cover only will set you back a hefty €149, or $205. Adding a PS4 along with that brings the price up to €599, or $826, which means there's a roughly $200 bump for the cover's installation. Maybe you can figure it out yourself?
[ Product Page ] VIA [ DamnGeeky ]


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text:
Fri 01
Ooh, pretty
Yes! It's a site redesign! Now there's a new book (Jennifer Government) coming, I decided it was time to update.
There are also some new Author Notes in Syrup Extras for those of you who like to marvel at how I ever managed to finish a novel with thought processes like these.


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Stem Cell Recipient Developed Mysterious Masses At Injection Sites
July 08, 2017
Following stem cell therapy, an adult patient experienced a new and previously unrecognized complication, which required removal of one of the kidneys, according to a case report appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The report suggests that stem cell therapy may cause patients to develop blood vessel and bone marrow masses, the long term effects of which are unknown.
Stem cell therapy holds great clinical potential for a variety of diseases. Therapy using stem cells from the blood has generally been viewed as safe, and researchers have planned clinical trials to expand this type of therapy to treat different conditions. However, a new report indicates that a previously undescribed complication may result. The case involves an adult patient with severe kidney disease, who was treated at a private clinic, by direct injection of her own stem cells into her kidneys. After a few months, one kidney developed bleeding and required removal.
Duangpen Thirabanjasak, MD, Kavirach Tantiwongse, MD (Chulalongkorn University, in Bangkok, Thailand) in consultation with Paul Scott Thorner, MD, PhD (The Hospital for Sick Children, the University of Toronto, in Canada and Chulalongkorn University) were involved in the removal and analysis of the kidney. They found that the patient had not benefitted from the treatment but, rather, had developed masses called angiomyeloproliferative lesions at the injection sites composed of a mixture of blood vessels and bone marrow cells. The remaining kidney eventually failed, and the patient ultimately died from an infection.
"This type of lesion has never been described before in patients, and we believe that this is either formed directly by the stem cells that were injected or that the stem cells caused these masses to form," said Dr. Thirabanjasak. She noted that because this was a unique occurrence, no one knows how these lesions might have behaved over time.
The authors conclude that their findings should serve as a warning to clinical investigators that the development of blood vessel and bone marrow masses may be a possible complication of stem cell therapy. Further research is needed to determine the circumstances that may cause these masses to form and to determine strategies to avoid this possible complication from occurring in the future.
In reviewing the results of this report in an accompanying editorial, Andras Nagy, PhD and Susan Quaggin, MD (Mount Sinai Hospital and the University of Toronto) noted that it provides a cautionary note and underscores a growing risk associated with the increased number of private clinics offering stem cell therapies to patients with little or no oversight from the scientific stem cell community. "Premature enthusiasm and protocols that are not fully vetted are dangerous and result in negative publicity for the field of stem cell research, and more importantly, may result in disastrous outcomes with no benefit to the patient," they wrote.
Disclosures: The authors of the study and editorial reported no financial disclosures.
The article, entitled "Angiomyeloproliferative Lesions Following Autologous Stem Cell Therapy" (doi 10.1681/ASN.2009111156) and accompanying editorial, "Stem Cell Therapy for the Kidney: A Cautionary Tale" (doi 10.1681/ASN.2010050559) appears online.
Shari Leventhal
American Society of Nephrology


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Game Boy Color
The Game Boy Color, or GBC, is a handheld console made by Nintendo. It is essentially a Game Boy Classic, except with the much needed capability of showing color, it is also slightly smaller in size, and a fair bit lighter than the classic.
Grand Theft Auto games for the GBC
- Grand Theft Auto 1 (1997)
- Grand Theft Auto 2 (1999)


text:
Predominantly open land on the edge of a settlement.
Please note that we will be updating this website in light of the revised National Planning Policy Framework, which was published on 24 July 2018.
Planning Help is a project of the Campaign to Protect Rural England. The Campaign to Protect Rural England exists to promote the beauty, tranquillity and diversity of rural England by encouraging the sustainable use of land and other natural resources in town and country. CPRE is not responsible for the content, services or reliability of links to external websites. All content © CPRE unless otherwise stated.


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Regular visitors will have noticed ever increasing amounts of spam on the Trading Gurus Community Forum. On November 24th 2012 we implemented some changes:
1. New users will be moderated 2. Registered users who have a post count of zero will not be able to view attachments or download code. 3. Registered users who have a post count of zero will not be able to create a new thread
As an additional countermeasure we anticipate introducing a modest paywall in the near future.
If this is your first visit here our apologies for the inconvenience.
Existing users may wish to contribute their ideas to this thread.
The business of making money, excluding investing, trading and gambling!


text:
Export 11 results:
Filters: Author is Castonguay, Annie [Clear All Filters]
Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells. Elife. 2016;5.
Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine. Neuropsychopharmacology. 2016;41(4):949-59.
Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain. J Neurosci. 2015;35(15):6057-67.
Microglia disrupt mesolimbic reward circuitry in chronic pain. J Neurosci. 2015;35(22):8442-50.
Extended two-photon microscopy in live samples with Bessel beams: steadier focus, faster volume scans, and simpler stereoscopic imaging. Front Cell Neurosci. 2014;8:139.
[KCC2: a new therapeutical target for the treatment of neurological diseases]. Med Sci (Paris). 2014;30(5):514-7.
Chloride extrusion enhancers as novel therapeutics for neurological diseases. Nat Med. 2013;19(11):1524-8.
Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis. Nat Neurosci. 2013;16(2):183-92.
QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile. Fundam Clin Pharmacol. 2012;26(5):599-608.
Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis. PLoS Comput Biol. 2011;7(9):e1002149.


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Your Hotel Direct credit:
with your
% off
RSP prices
It is surely appropriate to experience the lavish historical riches of London while staying in suitably luxurious accommodation. Happily this is a city that does not want for luxury and there's certainly no shortage of five star hotels in London to pick from. Whether you find the historic grandeur of London's palatial grand hotels irresistible or prefer the chic sophistication of its many stylish boutique hotels this is a city that does five star luxury better than anywhere else in the world. Impeccable service and splendid surroundings are the hallmarks of London's five star hotels and you'll find an exceptional selection of accommodation wherever you choose to base yourself. From the glitz and glamour of the West End or the more modish enclaves of the East, London offers an abundance of hotels with world class style and luxury wherever you look.
Crowne Plaza Battersea
Superb 90%
Battersea. Indulgent 5* with Spa and surprisingly affordable rates.
"Perfect hotel for me and my grandson" (20/8/2017)
"excellent value, superb breakfast" (3/5/2017)
Situated on the South bank of the River Thames opposite the scenic Chelsea Harbour Pier, the luxurious 5*... More info
InterContinental The O2
Exceptional 96%
O2 Spectacular hotel with full leisure facilities, close to the O2 and Canary Wharf
"Superb Hotel" (14/11/2018)
"Amazing!!! Service so good and facilities so lu..." (1/1/2017)
Overlooking the River Thames and Canary Wharf, the brand new InterContinental London The O2 is ideally si... More info
Radisson Blu Edwardian Hampshire
Excellent 89%
Leicester Square. Luxury 5* hotel in the most central of locations.
"Staff very friendly and helpful all facilities ..." (12/3/2020)
"Staff Excellent" (25/1/2020)
The Radisson Blu Hampshire is the only London hotel boasting a Leicester Square address. More info
Courthouse Hotel
Very Good 80%
Off Oxford St & Regent St. 5* contemporary hotel with Spa facilities.
"Great place to stay and so convenient for theat..." (23/7/2019)
"Lovely convenient hotel" (10/12/2017)
The Courthouse Hotel is a luxury 5 star hotel ideally located right in the heart of Central London. The c... More info
May Fair Hotel, A Radisson Collection Hotel
Excellent 85%
May Fair Exceptional, luxury hotel in the heart of Mayfair.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
Steeped in history, the magnificent 5* May Fair Hotel is nestled in the heart of affluent Mayfair. More info
Royal Horseguards
Superb 94%
Charing Cross. 5* near Covent Garden/Strand.
"Luxurious" (15/3/2020)
"Hotel perfectly located and excellent staff and..." (2/3/2020)
Built in 1884 this Grade I listed iconic building sits proudly on the banks of the Thames. More info
Courthouse Shoreditch
New hotel
Shoreditch Contemporary 5* hotel located in one of London`s most fashionable areas.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
Located in the heart of fashionable Shoreditch, the 5* Courthouse Hotel Shoreditch is cool and contempora... More info
The Bentley
Superb 92%
Kensington. Luxury 5* with spa facilities.
"Best hotel ever," (16/6/2018)
The Bentley Hotel offers opulent 5 star accommodation in a residential area of the Royal Borough of Kensi... More info
InterContinental London Park Lane
Exceptional 100%
Park Lane. Contemporary 5* hotel close to London`s major attractions.
"A delightful experience" (17/2/2018)
"Excellent service" (17/7/2016)
Located next to Green Park the Intercontinental Park Lane is ideally situated for guests looking to enjoy... More info
11 Cadogan Gardens
Superb 91%
Sloane Square. 5* hotel close to designer shopping.
"Excellent staff" (13/1/2019)
"Comfotable stay" (22/8/2015)
Nestled just minutes away from Sloane Square in the heart Chelsea, 11 Cadogan Gardens offers sumptuous 5*... More info
Langham London
Exceptional 95%
Regent Street. 5 star opulence above Oxford Circus
"Luxury" (30/12/2018)
"Exceptional!!" (2/9/2018)
It would be impossible not to be impressed by this hotel, the Langham epitomises all that is truly `grand... More info
Rathbone Hotel
Superb 92%
Off Oxford Street. Luxurious boutique 4* above Soho
"Friendly, accommodating staff. Spotlessly clean..." (20/3/2020)
"Excellent" (7/3/2020)
The Rathbone is a comfortable, intimate, boutique style hotel centrally located in London`s West End. More info
St. Paul`s Hotel
Superb 92%
Hammersmith. Stylish boutique hotel located 5 minutes from Hammersmith Tube Station.
"Exceptional" (24/11/2017)
"Spot on all round" (24/4/2017)
St. Paul`s Hotel is a stylish boutique hotel conveniently located near Hammersmith Tube Station, Kensingt... More info
Holiday Inn Whitechapel
Exceptional 100%
Whitechapel. Modern and stylish 4* Deluxe hotel in trendy East London.
"friendly helpful staff quality room facilities ..." (28/11/2018)
With easy access to tube stations and the Tower of London, Holiday Inn Whitechapel is conveniently locate... More info
Great Cumberland Place
Excellent 88%
Marble Arch. Fantastic Oxford Street location
"Great" (12/11/2018)
"Cumberland Hotel" (29/5/2018)
Great Cumberland Place provides 4* deluxe comfort within a prime location, ideal for business or leisure ... More info
Crowne Plaza Kings Cross
Excellent 86%
Kings Cross/ Bloomsbury. 4* hotel with pool
"Very happy with our stay." (24/2/2020)
"Crowns Plaza...always good!" (22/2/2020)
The Crowne Plaza London - Kings Cross hotel offers superb 4 star deluxe facilities close to the West End. More info
Pestana Chelsea Bridge
Excellent 89%
Battersea. Luxury 4* deluxe hotel with pool & spa.
"Gorgeous hotel superb location spotless rooms v..." (11/8/2019)
"Great room fantastic bed brilliant breakfast" (18/9/2018)
The Pestana Chelsea Bridge Hotel & Spa is an excellent base for visitors to London wishing to stay in a q... More info
Park Plaza Victoria
Superb 93%
Victoria. 4* deluxe close to Buckingham Palace.
"Park plaza Victoria brilliant" (29/2/2020)
"Brilliant" (10/12/2017)
Park Plaza Victoria is a 4 star luxury design led hotel 30 metres from Victoria station. More info
Park Plaza County Hall
Superb 92%
Park Plaza County Hall. Overlooking the London Eye
"Smart, great value and great location" (20/2/2020)
The Park Plaza County Hall is sumptuous purpose built four-star deluxe hotel, More info
Park Plaza Westminster Bridge
Superb 93%
Park Plaza Westminster Bridge. Opposite the Houses of Parliament
"Fantastic hotel" (4/1/2020)
"Good central location whilst remaining relative..." (23/11/2019)
The Park Plaza Westminster Bridge is one of the most modern and architecturally striking hotels. More info
Amba Marble Arch
Excellent 89%
Marble Arch. 4* near Oxford Street & Selfridges
"Excellent ambassador hotel" (14/5/2018)
"Great hotel" (19/3/2018)
Overlooking Oxford Street the 4 star deluxe Amba Hotel Marble Arch is located in the heart of London`s wo... More info
Radisson Blu Edwardian Bloomsbury Street
Superb 90%
Bloomsbury. 4* close to the British Museum..
"Excellent location, excellent hotel" (29/2/2020)
"A trendy hotel in a great location." (24/2/2020)
Just 100 metres from the British Museum the Radisson Blu Edwardian Bloomsbury Street is centrally located... More info
Holmes Hotel
Excellent 85%
Baker Street. 4* Boutique Hotel Close to Regents Park.
"Excellent hotel." (20/6/2017)
"Excellent hotel" (29/8/2013)
The 4 star deluxe Holmes Hotel, refurbished in 2019, occupies a prime location just momen the world-famou... More info
Crowne Plaza London Docklands
Excellent 85%
City of London. Stylish 4* Deluxe near the ExCel
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
The Crowne Plaza London Docklands is located in East London with the Royal Victoria DLR only 4 minutes` w... More info
Radisson Blu Edwardian Berkshire
Exceptional 97%
Oxford Street 4 star intimate hotel surrounded by some of London`s best shopping.
"Great Hotel" (22/12/2019)
"Radisson Blu Edwardian Berkshire." (24/11/2019)
Situated in the heart of London`s best known shopping area, Oxford Street, the 4* Radisson Blu Edwardian ... More info
Radisson Blu Edwardian Mercer Street
Exceptional 95%
Covent Garden. 4* hotel, perfectly located for Theatreland.
"fab hotel in superb location" (25/2/2020)
"Superb" (27/10/2019)
Ideally located in Covent Garden the 4* Radisson Blu Edwardian Mercer Street occupies an enviable positio... More info
Washington Mayfair
Excellent 86%
Mayfair & Piccadilly. Modern deluxe hotel in the heart of Mayfair.
"Good location and very good hotel" (29/12/2017)
"Beautiful, well positioned hotel where all the ..." (10/12/2017)
The 4* Deluxe Washington Mayfair hotel is located in the very heart of London on an upmarket side street.... More info
Amba Charing Cross
Superb 91%
The Strand. Trafalgar Square - Covent Gdn location
"Some road noise at night" (9/2/2020)
"Outstanding" (9/11/2019)
This landmark Grade 2 Listed hotel, the Amba Hotel Charing Cross, is situated in the very heart of the Ca... More info
Best Western The Boltons Kensington
Excellent 85%
Earls Court. A hotel in the perfect position for those looking to explore London.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
The Best Western Boltons Hotel is a clean and comfortable 4* occupying a prime location in the heart of E... More info
Hotel Shepherds Bush London
Very Good 80%
Shepherd`s Bush. 4* boutique hotel only 5 minutes from Westfield shopping centre.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
Hotel Shepherds Bush London offers luxury 4-star accommodation in the heart of West London. More info
Holiday Inn Kensington Forum
Exceptional 95%
Kensington. Superb 4* hotel close to the Natural History Museum.
"Excellent location" (10/7/2017)
Situated in London`s desirable Kensington, the Holiday Inn - Kensington Forum is a modern 4* hotel. More info
Princes Square
Excellent 85%
Bayswater Stylish converted Victorian townhouse near Notting Hill.
"Good location" (21/2/2018)
"Absolutely no complaints - Exceptional staff an..." (1/11/2017)
The Princes Square Hotel is ideally situated in the prestigious surroundings of Notting Hill and Bayswate... More info
Holiday Inn Brentford Lock
New hotel
Brentford. 4* hotel close to Twickenham Stadium.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
The 4 star Holiday Inn London Brentford Lock has a wonderful location overlooking the picturesque waterwa... More info
Crowne Plaza Heathrow
Exceptional 100%
Heathrow. 4* hotel with fitness centre and swimming pool.
"Very comfortable,clean,luxurious hotel" (5/6/2016)
"Excellent hotel and amenities" (16/4/2015)
Located close to the airport the Crowne Plaza London Heathrow is just a 15 minute ride away on the airpor... More info
The Continental Heathrow
Very Good 82%
Hounslow Central. Modern 4* with pool. Close to Heathrow Airport.
"Great room and good service from all department..." (3/6/2019)
"Fabulous" (4/4/2018)
The 4* Continental Hotel Hounslow is located just a 10 minute tube ride from Heathrow Terminals 1,2 and ... More info
Holiday Inn Heathrow M4
New hotel
Heathrow. 4* hotel with great transport links.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
Located close to the motorway the Holiday Inn London Heathrow M4 Junction 4 is conveniently situated for ... More info
Holiday Inn Kingston South
Superb 90%
Kingston-Upon-Thames. 20 mins. to London Waterloo
"lovely hotel" (9/11/2014)
"Real value for money - Friendly staff" (28/9/2014)
The 4* Holiday Inn Kingston South is set in a leafy area overlooking the River Thames. Guests can take a ... More info
Crowne Plaza Ealing
Exceptional 100%
Ealing. Stylish modern hotel in West London
"Fantastic location for London" (6/3/2016)
A stylish modern hotel in West London has great transport links for leisure and business travellers. More info
Radisson Blu Edwardian Heathrow
Excellent 85%
Heathrow. 4* hotel with gym and spa.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
Located just a short distance from Heathrow Airport the luxurious 4* Radisson Blu Edwardian Heathrow is w... More info
St George`s Wembley
Superb 91%
Wembley. 4* property overlooking the world famous Wembley Stadium
"Most welcome stay" (20/8/2018)
"Don`t be put off by the outside everything else..." (24/11/2016)
The 4 star St George Hotel overlooks Wembley Stadium and the iconic Wembley Arena More info
The Tower Hotel
Superb 92%
Tower Bridge. Opposite the Tower of London
"Highly recommended it" (8/3/2020)
"Wonderful view" (7/3/2020)
The luxurious 4* Tower Hotel Tower (formerly Guoman Tower) is a 2 minute walk from Tower Bridge. More info
Airlink Hotel Heathrow
Exceptional 100%
Hayes. 4* Modern hotel, close to Heathrow Airport
"Amazing staff" (18/4/2016)
The 4* Airlink Hotel is ideally located in Hayes, West London, just 14 minutes from Heathrow Airport. More info
Holiday Inn Wembley
Excellent 85%
Wembley. 4* hotel close to Wembley Stadium and Arena.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
The Holiday Inn London Wembley is situated next to Wembley Stadium and the SSE Arena, easily accessible f... More info
Holiday Inn Commercial Road
Superb 92%
East London. A new modern Hotel in London`s East End.
"Wonderful staff, wonderful hotel." (17/1/2017)
"Excellent" (2/11/2014)
Recently opened, the 4* Holiday Inn Commercial Road occupies a prime position in London`s vibrant East En... More info
Park Plaza Park Royal
Superb 90%
Park Plaza London Park Royal. New 4* hotel in West London.
"It`s a best of best hotel experience!!!" (23/9/2019)
"Great Stay" (23/11/2017)
The 4* Park Plaza London Park Royal is a great location to stay whilst visiting central London. More info
Westbourne Hyde Park
Exceptional 95%
Hyde Park. 4* Luxury Boutique Hotel.
"A very comfortable Hotel within easy walking di..." (17/4/2018)
Opened in 2016 The Westbourne Hyde Park is a contemporary boutique hotel just minutes from Hyde Park. More info
Park International
Excellent 85%
Kensington. 4* hotel ideally placed within walking distance of many attractions.
"The hotel was really ideal.very welcoming and g..." (27/10/2019)
"Excellent location and value for money" (26/6/2019)
Park International is a stylish 4*hotel in the heart of Kensington, an ideal base during a visit to Londo... More info
Holiday Inn Kensington
Very Good 83%
High Street Kensington. With pool and health club
"Good value for money" (2/11/2019)
"Nice hotel and even nicer staff!" (7/4/2019)
The 4* Holiday Inn Kensington is just off Kensington High Street and offers an unusual combination for ce... More info
Holiday Inn Camden Lock
Superb 92%
Camden. 4* hotel in one of London`s trendiest areas.
"Third time we stay in this hotel" (6/7/2017)
"Great location!" (9/4/2016)
Situated in one of London`s most fashionable areas, the Holiday Inn London Camden More info
Hotel Indigo Paddington
New hotel
Paddington. 4* hotel with great transport links.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
The 4* Hotel Indigo London Paddington is centrally located within a 2 minute walk of Paddington Station, ... More info
Radisson Blu Edwardian New Providence Wharf
Exceptional 98%
Canary Wharf. 4* hotel close to the O2 Arena.
"Exceptional service from arrival to departure !..." (29/2/2020)
"e" (16/2/2020)
The Radisson Blu Edwardian New Providence Wharf occupies an enviable position on a peaceful bend on the R... More info
Holiday Inn London Stratford
Exceptional 97%
Westfield Shopping Centre. 4* hotel overlooking the Olympic Park
"Peaceful night and a fab location." (7/12/2014)
"Fantastic hotel in the best possible location" (6/12/2014)
Located in the heart of Westfield Shopping Centre the Holiday Inn London Stratford City boasts an ideal More info
Holiday Inn Regents Park
Superb 93%
Regents Park. 4* hotel close to Madame Tussauds.
"A very comfortable stay" (29/10/2019)
"Great hotel in the West End" (21/8/2019)
Located in a leafy, tranquil area, the 4 star Holiday Inn London Regents Park offers a peaceful haven More info
The Cleveland
Superb 91%
Bayswater. 4* Studios and Suites. Near Hyde Park
"A must" (16/4/2019)
"Clean, comfortable room in an ideal location" (31/5/2018)
The 4* Cleveland Hotel is situated in a garden square just 5 minutes walk from Hyde Park More info
Ambassadors Bloomsbury
Excellent 87%
Bloomsbury. Contemporary hotel nr British Museum
"Reception personell were exseptional" (6/4/2019)
"Anniversary stay at the Ambassador Bloomsbury h..." (12/3/2019)
Ideally located in the literary district of Bloomsbury, the 4* Ambassadors Bloomsbury is just a 5 minute ... More info
Holiday Inn Bloomsbury
Superb 90%
Bloomsbury. 4* very close to the British Museum.
"Ideal location" (21/1/2020)
"Perfect" (13/1/2020)
Located near Russell Square and a few minutes` walk from the British Museum, the Holiday Inn London Bloom... More info
Hotel Indigo Tower Hill
Exceptional 100%
Tower Hill. 4* in London`s famous Square Mile.
"Excellent value" (26/4/2015)
The 4* Hotel Indigo London Tower Hill is ideally located in the Square Mile, London`s famous financial di... More info
Radisson Blu Edwardian Grafton
Superb 92%
Tottenham Court Road. Luxury 4 star hotel in the West End.
"Friendly, helpful staff.Nice,clean hotel.Good l..." (18/3/2020)
"Beautifully clean hotel with friendly staff" (20/2/2020)
Located on Tottenham Court Road in the sophisticated Fitzrovia area of Central London More info
Hotel Indigo Kensington
Exceptional 97%
Kensington. 4* hotel close to museums and designer shopping.
"Indigo hotel" (10/3/2017)
"Excellent!" (23/2/2015)
Situated in Kensington close to Earls Court, the contemporary 4* Hotel Indigo London Kensington offers fa... More info
Crowne Plaza City
Exceptional 95%
The City. 4* hotel with Champagne bar.
"Great location" (13/10/2019)
"Excellent location near Blackfriars Bridge" (9/8/2019)
Situated in London`s historic Square Mile in the financial heart of the city the Crown Plaza London the C... More info
Thistle London Hyde Park Kensington Gardens
Very Good 83%
Overlooking Kensington Gdns. Swift West End access.
"Ideal location." (26/2/2020)
"Excellent hotel" (27/5/2019)
The 4* Thistle London Hyde Park Kensington Gardens is a purpose built property overlooking Hyde Park More info
Radisson Blu Edwardian Vanderbilt
Excellent 86%
South Kensington. 4* close to Kensington museums.
"Excellent service from start to finish" (27/6/2018)
"Great London Hotel" (19/2/2018)
Located in fashionable South Kensington, the 4* Radisson Blu Edwardian Vanderbilt More info
Holiday Inn Oxford Circus
Excellent 87%
Oxford Street. 4* in fantastic central location.
"Great location" (21/2/2020)
"Welcoming staff and great location" (19/9/2019)
The centrally situated Holiday Inn London Oxford Circus occupies an enviable location in the heart of cen... More info
H10 London Waterloo
Exceptional 95%
Waterloo. Fantastic 4* Hotel close to the London Eye
"Lovely weekend break away" (16/9/2019)
"Superb!!" (31/1/2018)
The newly built H10 Waterloo is located a 15 minute walk from the London Eye and the London Aquarium More info
Thistle London Hyde Park Lancaster Gate
Excellent 87%
Hyde Park. Elegant 4* overlooking Hyde Park.
"Was lovely and the rooms were great and the gir..." (6/2/2020)
"Thoroughly enjoyed our stay at the Thistle Hyde..." (24/11/2019)
The 4* Thistle London Hyde Park Lancaster Gate is conveniently situated overlooking Hyde Park and Kensing... More info
Hilton London Olympia
Good 79%
Kensington. Kensington High Street.
"Lovely visit" (25/4/2017)
"Quick check-in and offered us breakfast as an a..." (12/3/2017)
The Hilton London Olympia is situated on Kensington High Street, one of London`s most prestigious shoppin... More info
Thistle Holborn
Superb 93%
Above Covent Garden. Serving Oxford St. & theatres.
"Nice stay" (10/3/2020)
"Welcoming" (19/2/2020)
The elegant 4* Thistle Holborn occupies a fantastic central London location in the heart of historic Bloo... More info
Danubius Regents Park
Excellent 89%
Regents Park. Opposite Lords cricket ground.
"All Services top class.." (23/8/2017)
"Excellent service. Staff really friendly and we..." (26/6/2017)
The Danubius Hotel Regents Park is superbly located overlooking both Lords cricket ground and Regents Par... More info
The Resident Kensington
Exceptional 96%
Kensington.Luxurious 4* boutique hotel
"Highly recommended" (1/12/2019)
"Lovely room and very helpful and friendly staff" (12/4/2019)
The Resident Kensington is a luxurious 4* boutique hotel located in the Royal Borough of Kensington & C... More info
Radisson Blu Edwardian Kenilworth
Superb 90%
Bloomsbury. Modern 4 star close to the British Museum.
"Amazing Hotel! Highly Recommended" (16/3/2020)
"Clean central and will continue o use subject t..." (15/1/2020)
The Radisson Blu Edwardian Kenilworth is a luxury 4 star hotel in the heart of literary Bloomsbury More info
Radisson Blu Edwardian Sussex
Superb 91%
Oxford Street Elegant, contemporary hotel.
"I love this hotel, it is beautiful and the best..." (18/12/2018)
"Outstanding!" (10/5/2017)
Situated in the heart of the West End, just off Oxford Street and 300 meters from Marble Arch, the elegan... More info
Ashburn Hotel
Exceptional 95%
South Kensington. Victorian house, turned boutique hotel situated on Cromwell Road.
"Comfort and Style." (12/1/2020)
"Very well appointed" (22/12/2019)
This Victorian house, turned deluxe boutique hotel is situated in the enviable position on Cromwell Road ... More info
The Resident Soho
Exceptional 97%
Soho.Affordable 4* luxury boutique hotel.
"Perfect location" (28/4/2019)
"Beautiful and clean" (20/3/2019)
The Resident Soho is nestled in the heart of vibrant Soho. More info
Club Quarters St Pauls
Superb 90%
St Pauls & Fleet St. Close to Millennium Bridge
"Nice room and great staff" (10/11/2019)
"Comfy and value for money" (16/12/2018)
The Club Quarters St Pauls derives its name from the Cathedral, which is adjacent to the hotel. More info
Club Quarters Gracechurch
Excellent 87%
Bank & Liverpool St. Stunning & 4 stops to West End
"Great hotel in a great location" (31/10/2015)
The Club Quarters Gracechurch is an excellent hotel located a short walk from the Tower of London and Tow... More info
Park Plaza Riverbank
Superb 91%
Park Plaza London Riverbank. Fantastic views towards the Houses of Parliament.
"Faultless." (15/3/2020)
"Lovely hotel, helpful staff" (10/3/2020)
This 4* hotel is a great location for sight-seeing. situated on the South-side of the River Thames near ... More info
Thistle Trafalgar, Leicester Square
Superb 90%
Trafalgar Sq. Great location below Leicester Square.
"Excellent location for Only Fools and Horses sh..." (12/2/2020)
"Excellent staff" (10/11/2019)
Just off Trafalgar Square, nestled in a quiet street adjacent to the National Gallery, close to Oxford St... More info
London Bridge
Superb 94%
London Bridge. Lovely 4 star close to Tower of London
"Excellent hotel" (9/3/2020)
"London break" (2/3/2020)
A very fine 4 star hotel, completed in summer 1999 but built behind a Georgian facade. The hotel is super... More info
Crowne Plaza Kensington
Superb 91%
Cromwell Rd. Fantastic 4* near the Museums of Kensington.
"Great hotel" (1/4/2016)
"Staff were fantastic" (18/3/2015)
Just a couple of minutes` walk from Gloucester Road underground station the Crowne Plaza London Kensingto... More info
Park Plaza Waterloo
Superb 94%
Waterloo. Modern, luxury 4* hotel with pool and spa facilities.
"Outstanding service" (8/3/2020)
"Very helpful when I left items in safe" (20/2/2020)
The Park Plaza London Waterloo is a 4* hotel on London`s South Bank. A fantastic base for sightseeing in... More info
The Grand at Trafalgar Square
Excellent 89%
Trafalgar Square. Exquisite building minutes from Covent Gdn
"Friendly helpful staff. Room just right with ex..." (26/8/2018)
"The Grand - Superb Friendly and Professional" (7/5/2017)
Centrally located just off Trafalgar Square the 4* Grand occupies Northumberland House. More info
The Belgrave
Very Good 82%
Victoria. Elegant 4* Hotel.
"Fantastic!!" (14/12/2019)
"Excellent hotel" (25/11/2019)
The Belgrave hotel is a elegant hotel located in the heart of Victoria and Westminster. More info
Thistle Piccadilly
Exceptional 95%
Piccadilly. 4* in the heart of Theatreland.
"Very Good Customer Service" (9/3/2020)
"Amazing" (8/3/2020)
The Thistle Piccadilly`s very central location makes this hotel an ideal base for guests wanting to explo... More info
Club Quarters Trafalgar Square
Superb 90%
Trafalgar Square. Restoration of opulent building
"Great staff" (16/2/2019)
"Within walking distance from the theatre. A lov..." (28/8/2018)
The beautifully restored 4* Club Quarters Trafalgar Square started life as the famous Victoria Hotel, wh... More info
Hotel Indigo Leicester Square
Superb 91%
Leicester Square Glamorous 4* hotel located in the heart of the West End.
"Central for everything" (5/3/2019)
"A hidden away gem of a hotel" (14/1/2019)
The Hotel Indigo - 1 Leicester Square is perfect for those looking to take in the theatrical glamour of L... More info
Holiday Inn Mayfair
Superb 94%
Mayfair. 4* with a great range of services.
"A great Hotel in a superb location." (12/5/2016)
"location !!" (5/2/2016)
Situated in Mayfair the Holiday Inn London Mayfair is in an ideal location to explore the many attraction... More info
The Resident Covent Garden
Exceptional 100%
Covent Garden. Modern 4* hotel in the heart of the West End.
"Good night sleep" (5/1/2020)
"Excellent services, rooms and cleanliness" (14/12/2019)
Opened in February 2019, the 4* The Residen Covent Garden is ideally situated for those wanting to explor... More info
Amba Hotel Grosvenor
Excellent 87%
Victoria Station. Close to Buckingham Palace
"Staff very helpful and friendly great room" (4/3/2020)
"Faultless" (9/2/2020)
Following a multi-million pound refurbishment completed in 2019, The 4* Amba Hotel Grosvenor, a classic r... More info
The Resident Victoria
Exceptional 96%
Victoria. 4* hotel close to Buckingham Palace.
"Very good service and great location" (9/9/2019)
"First class" (5/2/2019)
The Resident Victoria is a luxurious boutique hotel located a short walk from Buckingham Palace. More info
Holiday Inn Express Stratford
Superb 92%
Stratford. Contemporary 3* deluxe hotel, just 10 minutes from the O2.
"Lovely clean, nice large room, happy helpful st..." (4/2/2015)
"Great hotel" (30/8/2014)
Located in Stratford, in the heart of East London, the 3* deluxe Holiday Inn Express London Stratford is ... More info
Crowne Plaza London Albert Embankment
New hotel
Waterloo. 4* Modern Hotel with Views Over River Thames.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
The 4* Crowne Plaza London Albert Embankment is a newly opened, contemporary hotel overlooking the River ... More info
Staybridge Suites London Stratford
Exceptional 95%
Westfield Shopping Centre. 4* suites located in the shopping centre.
"Too hotel in Stratford" (2/1/2017)
Situated inside one of the UK`s largest shopping centres, Westfield Stratford, the 4* Staybridge Suites L... More info
Best Western London Ilford
New hotel
East London 3* Budget Hotel, Close to Railway Station.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
The 3* Best Western London Ilford Hotel is a comfortable property close to the railway station with good ... More info
Best Western Corona
Very Good 83%
Victoria. An elegant Victorian conversion in a great location.
"Lovely Stay" (21/12/2019)
"Great location and lovely staff" (27/7/2019)
Housed in an elegant Victorian conversion, the 3* Corona Hotel brings together the timeless features of y... More info
Best Western Greater London
New hotel
East London 3* Budget Hotel with good transport links.
Cheapest price guaranteed
UK-based customer service with freephone: 0800 633 8000
The 3* Best Western Greater London is conveniently located close to Ilford railway station, just 2 minute... More info
Holiday Inn Heathrow Ariel
Exceptional 100%
Heathrow Airport. 3* hotel close to terminals 1,2 and 3.
"Clean and functional room .Good restaurant .Eas..." (7/7/2017)
"Super single room" (8/6/2015)
The 3* Holiday Inn London Heathrow Ariel is just a 15 minute shuttle bus ride from the airport, making it... More info
Best Western London Highbury
Excellent 87%
London. A hotel which enjoys the luxury of a charming location with views over Finsbury Park.
"Very comfortable stay, excellent location, plea..." (5/3/2020)
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Point A Kings Cross
Excellent 86%
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Excellent 85%
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Exceptional 100%
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"Excellent value for money" (5/3/2020)
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Point A Canary Wharf
Excellent 89%
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"Lovely helpful staff" (20/11/2019)
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Thistle Heathrow T5
Good 77%
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Holiday Inn Express Heathrow T5
Exceptional 100%
Slough. Modern accommodation close to Heathrow Airport.
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Best Western Plus Vauxhall
Superb 90%
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The Bridge Hotel
Good 73%
Southbank. 3* hotel offering comfortable accommodation in the heart of London.
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Point A Liverpool Street
Excellent 85%
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"Little gem" (14/5/2019)
"Great location, great service, great weather!" (16/7/2018)
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Point A Shoreditch
Excellent 89%
Shoreditch. 3* Modern Hotel with Compact Rooms.
"Nice clean hotel. Staff were friendly and helpf..." (1/4/2019)
"Hotel was superb" (19/1/2019)
The Point A London Shoreditch is in the heart of this fashionable part of East London More info
Holiday Inn Express Greenwich
Excellent 89%
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Holiday Inn Express Limehouse
Exceptional 100%
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New hotel
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Holiday Inn Heathrow T5
New hotel
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Holiday Inn Brent Cross
Superb 91%
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"Ten after ten for cleanness" (3/9/2017)
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Holiday Inn Express Ealing
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Point A Westminster
Very Good 80%
Waterloo. 3* Modern Hotel with Compact Rooms close to the Southbank.
"The strangest hotel I`ve ever stayed in." (22/5/2018)
"Thoroughly recommend" (13/4/2018)
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Point A Paddington
Excellent 89%
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"Beautiful room, clean and spacious room. We had..." (15/9/2019)
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Byron Hotel
Very Good 83%
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Holiday Inn Express London City
Very Good 82%
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Holiday Inn Express Vauxhall
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Point A Kensington Olympia
Excellent 85%
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Holiday Inn Slough Windsor
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Thistle Barbican
Excellent 85%
City Of London. Complimentary use of Leisure Club & Pool and FREE Wi-Fi
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Thistle Bloomsbury Park
Excellent 86%
Bloomsbury. Just above Covent Garden and Drury Lane.
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Staybridge Suites Vauxhall
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Oxford Street. Budget price West End hotel.
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text:
It's hard to describe what's going on with the America's Cup Finals taking place this month out on San Francisco Bay—hard because, frankly, it's painful.
Larry's Ellison's Oracle Team USA won its first yacht race on Sunday only to lose its fourth race in the series on Tuesday and then go on to lose two more races on Thursday. The epic losses, some of over 1 minute in length, have made his well-funded team members look both embarrassed and embarrassing.
How Ellison spends his money, of course, is nobody else's business. However, advisors often can (and should) be a moderating influence over the "toys" on which their high-net-worth clients like to spend money.
The America's Cup is showing that Ellison, as well as other fellow-America's Cup investor and Swedish billionaire Torbjorn Tornqvist, could use some moderation.
True, just a few days ago, Oracle Team USA—which boasts mainly non-U.S. leadership and membership—looked like it might be able to stage a comeback. But after its abysmal performance in the fifth race on Tuesday, the team took its one "pass" and declined to participate in the sixth race, which was set for later the same day.
Emirates Team New Zealand is clearly able to race upwind, or nearly into, the wind more quickly, aggressively and capably, leaving Team USA with very few options on how to win a race. Team USA can't out-tack or out-maneuver the Kiwis either, so it played the only card it had left on Tuesday; it's won one race out of seven, but is still in negative territory in terms of points, thanks to cheating and penalties associated with its conduct in previous races.
It's worth noting that, with all his billions, Ellison's turned the America's Cup race into a competition that relies so much on money and technology that it's become a contest between aero-catamarans. The boats are expensive to build and with wing-shaped sails as big as airplane wings and complicated foiling systems they're also incredibly difficult to sail.
Ellison had hoped this year's America's Cup would ignite new interest in the sport of sailing. Unfortunately, the opposite seems to be true. The boat designs and accidents, one of which ended with the death of a British Olympian and Team Artemis leader, have left the general public more alienated from the sport than ever.
What Donald Trump is to the East Coast, Larry Ellison is to the West Coast. The entrepreneur and his billions are now the butt of more jokes than before the competition started.
(In Larry's world, his Miss Universe contestant essentially chose to not walk down the catwalk for fear of falling or stumbling, crumbling under pressure or worse.)
Combine Tuesday's decision to not race in the second contest on the day with the cheating debacle (related to earlier America's Cup races that left Oracle Team USA with two fewer teammates in the current battle) and you have a lot of people thinking, and saying, that all the money in the world can't win you a yacht contest. For that matter, it can't even keep you in it.


text:
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Overhead Fans: Employees Love 'em, Birds Don'tMay 1, 2012
Metal service center Coilplus Ohio (Springfield) recently sought a solution to uncomfortable heat and unwelcome birds during the summer, as well as a to avoid product loss from rust due to shifting spring and fall temperatures, and cold spots during winter. Its goal, according to slitter supervisor Toby Schofield: "To make the guys on the production line more comfortable. And because we're a steel service center, it's best to have some air movement during humid days or you get a lot of rust."
Schofield tried using pedestal fans, but found the small, noisy units created a hazard on the shop floor. Ultimately, the solution was installation of five 24-ft.-dia. Powerfoil X fans from Big Ass Fan Co., Lexington, KY. The key to the effectiveness of Powerfoil X (and other large-diameter low-speed fans) is the volume of air generated by the fans' 10 hollow-core airfoils with winglets, which generates a perceived cooling effect of as much as 10 deg.
"The fans generate a nice, constant flow of air," says Schofield, "which the employees seem to really appreciate. Also, beginning each spring, we used to have a lot of birds in the building, and tried all kinds of device to get rid of them. With the fans, we no longer have that issue." Schofield also reports that rust has been completely eliminated since the fans were installed.
The benefits of Big Ass Fans aren't limited to the spring, summer and fall months. During colder weather, the fans help destratify the company's warehouse. Stratification occurs due to a significant temperature difference (10 to 30 deg.) from floor to ceiling. The use of large-diameter low-speed ceiling fans solves the problem by moving large volumes of air without creating a draft.
At Coilplus, the fans work hand-in-hand with the warehouse's radiant heaters to keep warm air at the employees' level.
"Our radiant heaters are 25 ft. in the air," says Schofield, "so you know it's not really reaching the guys on the floor. The fans push the heat down."Big Ass Fans: 877/244-3267; www.bigassfans.com
View Glossary of Metalforming Terms
See also: Big Ass Fans
Technologies: Safety
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text:
Alley of Roses
The Alley of Roses was a street in Gondolin, the northern entrance to the Square of the Palace. During the Fall of Gondolin it was burned and destroyed by Fire-drakes. It is mentioned in the Fall that it was once a fair place to walk in, and it can be assumed from its name that it was a sort of garden-street bordered by roses.[1]
- ↑ J.R.R. Tolkien, Christopher Tolkien (ed.), The Book of Lost Tales Part Two, "III. The Fall of Gondolin", p. 183


text:
Galvanic Skin Response(redirected from electrodermal response)
Also found in: Dictionary, Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to electrodermal response: Psychogalvanic Reflex, galvanic skin responses
Galvanic Skin Response
A physical response in the skin due to some stimulus. For example, turning red when one is nervous is a galvanic skin response. Some marketers measure galvanic skin responses on test subjects of advertisements. Proponents believe this is an objective way to determine a test subject's response to an advertisement, though critics contend that this practice does not sufficiently account for outside stimuli that may affect measurements.


text:
The B.C. government hardened its stance in the debate over the controversial Northern Gateway Pipeline on Wednesday, using a late-afternoon news release to fire a direct shot at Enbridge.
"The responses from Enbridge/Northern Gateway to cross-examination by our legal counsel are too often incomplete and lacking in commitment," said the statement from Environment Minister Terry Lake after a day of pipeline hearings in Prince George.
"Their answers suggest that the company is not taking the very real concerns of British Columbians seriously."
Wednesday's hearings focused on leak detection along the planned pipeline, with a lawyer from the province noting that the ability to detect leaks won't be known until the pipeline is built and pumping oil through the remote wilderness of northern British Columbia.
Premier Christy Clark's government, which originally avoided taking sides in the pipeline debate, has become increasingly involved in the last few months.
Over the summer, Clark laid out five elements her government says it needs before it will consider a heavy oil pipeline, and Clark has met with Alberta Premier Alison Redford over getting a greater share of the economic benefits.
But until now, she has not waded directly into the details of the debate, and has refused to meet with officials from Enbridge over the project, saying it would be inappropriate to do so until the review is complete.
In his statement Wednesday, on the second day of environmental assessment hearings in Prince George, Lake took aim at Enbridge for not committing to key elements, such as enhanced leak detection systems or an automatic shutdown.
"One thing that is crystal clear after the last two days is that Enbridge/Northern Gateway is putting off making commitments about including these systems in the pipeline design until after they get approval to proceed," Lake said.
"We believe that the only way to protect British Columbia's interests is to ensure that these commitments are made up front, so that everyone will understand how they intend to run this project."
New Democratic Party leader Adrian Dix, who opposes the Northern Gateway pipeline, said he believes Wednesday's comments are all about politics.
"What we've had now for really a couple of years is a government that hasn't been serious about its approach, and B.C. has paid the price for that," he said in an interview after the government statement was released.
"Now, late in the day, having finally heard what British Columbians had to say, the government is playing catch-up," he said, adding he thinks the tactic will not play well.
"I think what people in B.C. want are serious, well-considered positions, not positions that change every day based on the Liberal party's latest polling," he said. "What we've had from the Liberal party, sadly, is principally theatrics," he added.
"They want to be on all sides of this question. I appreciate their political desire to do that, but I think what people want is a government that is clear and straight with them about important issues."
The government news release comes a day after former B.C. energy minister, and now Conservative senator, Richard Neufeld, questioned whether the project will ever go ahead.
In an interview, Neufeld said Enbridge has so badly mismanaged the $6-billion project that he questions whether the Calgary company has the public credibility to proceed even if the National Energy Board approves the application next year.
"I just think Enbridge has left such a sour taste in most peoples' mouths."
During Wednesday's hearing, lawyer Chris Jones, acting for the B.C. government, focused on the company's ability to detect leaks along the pipeline.
"So is what you're telling me that the actual sensitivity of a pipeline — perhaps this pipeline, along with other ones — can only be determined when it's actually been constructed and you're able to test that actual pipeline in operation?" he asked.
Responded Barry Callele, director of pipeline control systems and leak detection for Enbridge Pipelines Inc.: "We have a quite an operating history.... It's not an issue of trust us, wait 'til construction."
Testing is and has been underway, Callele said, and test results show the estimates provided in the project proposal are conservative.
Said Jones: "But I guess the answer to my question is still: 'We don't know until it's been built.' Isn't that right?"
Callele responded: "I think we know what we know today. We'll know more at every phase along the pipeline construction project and we'll know emphatically or empirically at the time that fluid withdrawal tests are done at different sections of the pipeline."
Callele said there would be five overlapping leak detection systems on the twin pipelines that would carry diluted bitumen to the tanker port in Kitimat and condensate from Kitimat back to Bruderheim, Alta., including aerial surveillance, foot patrols, and 132 monitored pressure valves along the route.
"We will have one of the best instrumented pipeline systems not only in North America, but probably the world," Callele told the panel.
Jones noted that U.S. data indicate there were 31 leaks from Enbridge pipelines in that country since 2002, and six of the 10 largest spills by volume in that time were from Enbridge pipelines. Of those six, none were detected by Enbridge leak detection systems, Jones said.
Specifically, Jones raised questions about the pipeline's design and about spills along Enbridge pipelines in the Northwest Territories and one in the Kalamazoo River in Michigan — a massive spill that took two years and almost $800 million to clean up.
"Enbridge has admitted that procedural violations occurred during the Marshall incident," Callele said, referring to the Michigan spill. He said procedural and "cultural" changes have been implemented since then.
John Carruthers, president of Enbridge Northern Gateway Pipelines, said outside the hearings that people have concerns about whether the pipeline can be built and operated safely, and the questions being raised in the hearing room are "very legitimate." But Northern Gateway is a state-of-the-art system, he said. "Whatever industrial activity you have, it has some element of risk."
"The real key is to try to get that as low as possible. In our case, we're trying to get that to zero. So that's the direction you're going and you try to do the best you can with processes, with people and with technology."
His sentiments were echoed 800 kilometres away at a conference on pipeline safety organized by the B.C. Chamber of Commerce in Vancouver.
Ziad Saad, a vice-president of the Canadian Energy Pipeline Association, said data collected from members show there have been about three spills annually for the past decade.
"Clearly 2009 and 2011 have not been our best years, but overall the decade is much better (than) the decade prior, so overall pipelines are getting safer," he told attendees.
"We know the public has high expectations and we have high expectations of ourselves, so our goal is zero incidents," he added. "We don't pretend that we are here today at zero incidents and we don't pretend that we're going to be there next year.
"But that remains the goal. Period."
Janet Holder, an executive vice-president at Enbridge, told the Vancouver meeting the technology to detect leaks has continued to evolve, especially over the last five years.
"There's new technologies we're testing actually as we speak that will find a tiny pinhole leak in a pipeline that cannot be possibly found before," she said.
"We work very closely with companies like GE to develop new technologies and new ways to ensure the health of the pipelines."
The conference also heard that tanker traffic off British Columbia's coast will increase dramatically if Northern Gateway and a proposed Kinder Morgan pipeline expansion go ahead.
The number of tankers plying the coast would rise from 100 at present to 550, said Jonathan Whitworth, CEO of Seaspan and a representative of Canadian companies involved in coastal marine transportation, ship escorts and ship repair.
"I understand, that's a significant jump," he said.
But he noted some 600 commercial vessels move each day through the Strait of Dover, in the English Channel, and about 22,000 tankers traverse the Singapore Strait.
"That's a super highway and those super highways today are extremely safe," he said, noting the picture has much improved since the 1970s.
"I do believe tankers can safely navigate the world, we've seen it right here in Vancouver and I know that it can be done for many years to come."
Saad said oil companies in Canada abide by the best codes and standards for pipeline design, construction and operation in the world, but the industry has fallen down on transparency.


text:
If you are an autism type like me, and of course you are or you wouldn't be reading this, get your calendar out.
The UC Davis MIND Institute's Distinguished Lecturer Series begins its ninth season of public lectures by nationally and internationally-recognized researchers in neurodevelopmental disorders on Wednesday, October 13, 2010 beginning at 4:30 p.m.
These monthly presentations (October 2010 – June 2011) are intended for both specialists and community members. All lectures are free and open to the public and no reservations are necessary.
There is so much new and exciting research in the field of autism, and you owe it to yourself and your child to be up to speed! Plus, it is fun to go to the MIND Institute. If you live near an Amtrak Station, try the Capitol Corridor, (fun, quick,relaxing, no traffic)
Wednesday, October 13, 2010, 4:30 p.m. – 6 p.m.
Kevin A. Pelphrey, Ph.D.
Yale University
Neural Signatures of Atypical Brain Development in Autism
A little about Dr. Pelphrey:
Dr. Pelphrey has received a Scientist Career Development Award from the National Institutes of Health, a John Merck Scholars Award for his work on the biology of developmental disorders, and the American Psychological Association's Boyd McCandless Award for distinguished early career theoretical contributions to Developmental Psychology. His research program is funded by the National Institutes of Health, the Simons Foundation, Autism Speaks, and the National Science Foundation.
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Unveiling the Veil in Contemporary Iranian Art and Literature
In 1979, Ayatollah Khomeini mandated that all Iranian women must observe an Islamic dress code, which included wearing the veil, under the threat of death for those who refused to abide by these laws. This happened at about the same time that the totalitarian leader of my own country, Nicolae Ceausescu, was starting to impose draconian measures on Romanian women. Between the years 1979 and 1989, Ceausescu instituted a series of laws that controlled women's sexuality and reproduction by banning birth control and abortion. This was part of his narcissistic fantasy of doubling the population of the country, so that he could have more power. Eventually, as I described in my novel Velvet Totalitarianism, such measures lead to tens of thousands of unwanted children, many of which were placed in unimaginably bad conditions in the infamous Romanian orphanages. To my mind, both measures—in Iran and in Romania–represented a way of establishing power over women rather than being a reflection of religious or ideological (communist) values.
Having been sensitized early in life to these displays of totalitarian power, many years later, when I read Azar Nafisi's memoir, Reading Lolita in Tehran (2003), I was especially moved by the author's critique of the uses of the veil to control Iranian women's bodies. I was also very impressed by her creative allusions to Anglo-American literary history—the book is divided into four sections–Lolita, Gatsby, James and Austen–to launch her compelling cultural critiques. Many of you have probably already read this book, but if you haven't, I highly recommend it. Vladimir Nabokov's classic novel, Lolita, about a sociopathic sexual predator whose fetish is prepubescent girls functions as Nafisi's main metaphor for Iranian laws, which, she states, imposed "a dream upon our reality, turning us into figments of imagination." These female figments are objects of simultaneous control and temptation: temptation through prohibition by hiding the female body.
Recently, I ran across the images of an artist who, I believe, launches an equally powerful and creative critique of the veil by unveiling women. Majeed Benteeha is an Iranian-born photographer, poet and aspiring film producer. Moving back and forth between Tehran and New York City, he simultaneously combines and clashes both worlds, in a spectacular mix that challenges cultural assumptions on both fronts. His images often feature veiled women posing nude in an iconic fashion that seems more sacred than profane. Benteenha's strikingly original photography violates religious orthodoxies–about feminine modesty, about the religious and social connotations of the veil–only to show us another way to respect women and all that they represent: love, maternity, sensuality, desire, intelligence.
His images are simple, beautiful, erotic and dramatic. They include symbols associated with the Muslim faith, but also seem very European in many respects. Perhaps unwittingly, Beenteha's photography alludes to works like L'Erotisme, by the French anthropologist and philosopher Georges Bataille, which presents the sacred as inextricably related to the profane: not just for Muslim societies, but for all cultures in general. Bataille famously states: "The essence of morality is a questioning about morality and the decisive move of human life is to use ceaselessly all light to look for the origin of the opposition between good and evil." It seems that is precisely what Beenteha's artistic short film below underscores, in its mirroring and contrast between a universal modernity and Muslim tradition; between light and dark; between masculine and feminine; between tenderness and predation; between desire and contempt. You can view his photography and artistic films on the links below.
Claudia Moscovici, postromanticism.com