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A.) The body
-- Genetic modification. By the future envisioned in 2312, it seems that the human genome has become more of a suggestion than a hard code. Swan herself has apparently numerous modifications to her brain, and it seems the majority of the body is malleable either through this direct modification, or circumstantial influence like differing gravity in asteroids or on terraformed planets or biospheres.
-- Cybernetics. Swan also has a qube implanted in her head, and it seems this may have been common, if not slightly taboo, as of several years before the beginning of the story. Each qube seems to link directly into one's senses and can perform many various tasks from calculations to movement tracking, coordination, and even recording its human's experiences.
B.) The landscape
-- Terraforming. By 2312, it seems Mars has been completely terraformed and Venus is being eyed as the next candidate. The concept of terraforming is such a lofty dream in most near-future science fiction that actually managing to turn a planet like Mars, currently desolate and totally unlivable, into a reflection of Earth, would be such a monumental triumph that it would redefine the history of the universe.
-- Ascensions. Asteroid habitats designed by those like Swan are used (to questionable ethical effect) to experiment with different combinations of plant and animal life, creating entirely unique biomes which never existed—and never could have existed—on Earth.
C.) Life
-- Ascensions, again. Their existence proves further that humanity has gained unprecedented control over the formation and progression of life. To that note, some asteroid biomes are apparently used only for preservation of what was lost on Earth, doing so only where it was possible to save in the greater Solar System what was ruined there.
-- Genetic modification. Again. It seems that through scientific advancements, humanity has not only learned how to alter itself on a biological level, but to prolong its own life and create extremophile individuals capable of withstanding harsher conditions and greater punishment than we in the present might. For example, those on Mercury who, with the aid of technology, can survive standing in direct sunlight which would prove
D.) The community/collective
-- Terminator. The city that slides upon rails over the surface of Mercury, a tiny biosphere dome community kept vibrant and lively on a molten planet only by the collective effort of its residents. When the city is ultimately doomed by the destruction of its rails, it seems it is evacuated in its entirety within a matter of moments.
-- The Mondragon Accord itself. While it seems Earth and its affiliations in space are still gripped tightly in suffocating capitalist systems, those who have escaped them, like Mars, take more socialistic approaches to maintain their populations.
2. Though it seems we're still a little early in the plot, it's difficult to imagine its raw material concerning anything other than the conflicts of public and private, capitalism and the public interest. Earth when compared to the rest of the Solar System almost acts like a foil character to a group of protagonists, the nightmare origins that the settlers of the planets and moons must try to avoid recreating while having little limitation in doing the very things that led to them. Given that the main secretive plot seems to be something concerning Earth and its affiliations in space causing unsustainability throughout the entire Solar System, particularly the capitalist systems still strangling the planet and its peoples even after decimating its ecosystem, I would struggle to name many possible alternate interpretations sparing major twists in the rest of the book.
A potential alternative, as a few others have pointed out in this forum, might be a direct focus on environmental caretaking and the consequences for failing to do so. Robinson describes on Earth exactly that which is expected in a worst-case climate crisis scenario; high shoreline rise, resulting in the loss of massive swaths of coastal regions including the entirety of Florida and New York City; the loss of Earth's ice caps and sheets in their entirety, and the decimation of its biosphere except for those species fortunate enough to be uniquely qualified for survival in dramatically altered habitats. It seems the best humanity can do is attempt to reproduce Earth elsewhere, such as on Mars or Venus or in asteroid biomes, but the repeated implication seems to be that even their best collective efforts can still only create echoes of our true origins.

subset: commoncrawl


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COVID-19: We are shipping as normal, but occasionally orders may take 2-3 days to complete.
We use Royal Mail first class post, which should arrive next day, however, some orders are taking considerably longer to arrive. Please understand that once a parcel leaves the shop, I have no control over its progress. Please be kind when informing me that your order has not yet arrived. Believe me, I'm as frustrated as you.
Due to a family emergency, the shop will be closed Tuesday to Friday (11/8-14/8) this week. Orders placed after 2pm Monday will ship the following week. Stay safe, everyone <3
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WICT Announces Forum Speakers
Women in Cable & Telecommunications announced the roster of speakers at its upcoming WICT Forum.
The 2006 WICT Forum will be held March 8-10 at the Marriott Marquis in New York as part of the Spring Cable Week created by WICT's partnership with Cable Positive.
WICT said the Forum will kick off Wednesday, March 8, with a discussion of cable visionaries including David Juliano, senior vice president and general manager, Comcast Online; and Dennis Quinn, executive VP, business development at Turner Broadcasting System Inc., moderated by Hallmark Channel senior VP of distribution and service Janice Arouh.
Later that day, keynote addresses will be delivered by: Deborah Blackwell, executive VP and GM, SOAPnet ("Following Your Passion"); Beth Comstock, president, NBC Universal digital media and market development("Introducing New Ideas and Change Into an Organization"); Jenny Evans, performance coach, Human Performance Institute ("Utilizing Energy Management vs. Time Management"); andJim Carroll, international futurist, trends and innovations expert ("Opportunities for the Future").
There will be two panels Wednesday afternoon:
"Broadband: Have You Heard the Latest Word?" will be moderated by David Payne, senior VP and GM, CNN.com (www.cnn.com) and feature Amy Banse, president, Comcast Interactive Media; Tanya Van Court-Cayo, GM, ESPN Broadband and Interactive; and Sue Clark, VP, Scripps Networks Interactive.
And "How Does Technology Impact the Flexibility of Content and What Could Be Headed Our Way?" will include Yvette Gordon-Kanouff, corporate VP, SeaChange International Inc.; Mike Hayashi, senior VP, advanced engineering, Time Warner Cable; Ralph Brown, chief technology officer, Cable Television Laboratories Inc.; Bob Zitter, CTO, Home Box Office; and Ray Sokola, CTO, Motorola Inc. connected-home business.
Finally, Thursday morning will feature a keynote on high-performance teams by Grace Killelea, VP of human resources for Comcast Spotlight.


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Eugene, OR
Organic food manufacturer and distributor, focused on Pacific Northwest-Grown and Farm Direct relationships for beans, grains, nuts, seeds, dried fruits, honey, sweeteners, oils, nut butters (no peanuts), granolas and trail mixes.
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Self-distribution in western Oregon, along I-5 and to the coast, and works with several other distributors to reach Bend and other areas.
Information last updated: Aug. 20, 2019, 4:17 a.m.


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Student expelled from private Halifax college wins court case
March 8, 2010
Last Friday, a Nova Scotia small claims court ruled in favour of a dissatisfied student expelled from the Halifax campus of the Centre for Arts and Technology, a private institution. The student was kicked out last September after he reportedly violated a policy banning students from speaking negatively about the school when he told a pair of prospective students on a campus tour that the centre is a waste of money. The court found the expulsion was unjust because the school did not inform students about such a policy. The school has been ordered to refund the student $15,600 in tuition, and pay $100 in damages. Halifax Chronicle-Herald


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Accent Carpet Cleaning
State: North Dakota
Post: 58103-2236
County: Cass
City: Fargo
Address: 3551 4th Avenue SW
Phone: (701)293-6000
Fax: (701)237-0535
Email: unknown
Contact Owner: Mike Arnold
Web site: www.accentcontracting.com
SIC code: 721704 Industry group: Personal Services, Business category: Carpet & upholstery cleaning, Subcategory: Carpet & rug cleaners
Employees: 75
Gross Annual Sales (Revenue): 4,500,000
Description: Accent Carpet Cleaning is a business categorized under carpet & rug cleaners, which is part of the larger category carpet & upholstery cleaning. Accent Carpet Cleaning is located at the address 3551 4th Avenue SW in Fargo, North Dakota 58103-2236. The Owner is Mike Arnold who can be contacted at (701)293-6000.
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Location & access map for "Accent Carpet Cleaning"
about: Accent Carpet Cleaning (Personal services)


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As part of UK government Open Data, the boundaries of freehold properties can be viewed online for free. Each plot is identified by a number, called the INSPIRE-ID. INSPIRE is so called as it is from an EU directive, the Infrastructure for Spatial Information in the European Community. This gives a cadastral map for the UK, similar to what other European countries have had.
The access to this map is found via the data.gov.uk website and presents a map of the Uk that you have to zoom in to get the area you want.
Click here for Mitcham (opens in a new window or tab).
Select the Backdrop Map Projection as British National Grid to flatten the map:
Zoom in on the map by using the slider or double clicking. The map area may be blank as it takes a while to get all the data.
To get a description of the plot, make a note of the INSPIRE-ID number and do a search on the Land Registry website.
An example is Vestry Hall. On this clip of the map
the INSPIRE-ID 48379202 seems to encircle the fire station. Putting this into an INSPIRE-ID query gives


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I'll start by saying, I will not sugar-coat this review. This book contains some great techniques for dealing with people who aggressively try to manipulate you. That being said, the book is SO incredibly outdated in its voice and approach that I found it difficult to read it without its context being ironic. For me, the voice of the book overshadows its intent and helpfulness, but doesn't change the fact that I did benefit from reading it.
The examples used in the book are lengthy and repetitive. This is good because the redundancy of it programmed my mind to look for examples of those instances in my own life where I could apply the concepts of the book. A light bulb began going off in my mind when I'd experience an opportunity to try out one of the techniques described in the book. Over time, it has helped change my attitude and approach toward aggressive and manipulative people.
The book gives concrete techniques for applying in your everyday conversations: BROKEN RECORD, FOGGING, FREE INFORMATION, NEGATIVE ASSERTION, WORKABLE COMPROMISE, NEGATIVE INQUIRY. I began using them, and they do work! I occasionally go back and re-read chapters because it does take practice... but eventually it becomes more second nature and your confidence level builds as a result.
It is painfully obvious that this book was written in the 70s, with the male author using phraseology and examples that are misogynistic, self-congratulatory, racially charged, patriarchal, and bigoted. In a way, it is good to see how far we have come since the Civil Rights movement, but I really wish someone would publish an updated edition of this text that uses relevant, objective examples that do not detract from the overall purpose of the text. Personally, found it very annoying to waste so much time prodding through excessive ego-driven banter to find the nuggets of useful information. I wouldn't have kept going if the nuggets hadn't been so needed and useful. If you want an example, just look at the so-called Table of Contents. It's more like a glossary or appendix that provides a cluttered description of every chapter rather than just a simple chapter name and page number. I can take my own notes, thank you... and I prefer the appendix to be at the end of the book.
Fun fact: The author mentions sex so much in the book that I actually began playing a game to see if I could read through more than two pages with out seeing a reference to sex. The answer is no.
If you can tolerate the author's voice long enough to get through this book, it is admittedly very useful.
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What could the legends Coppi and Bartali, the world champion Primo Carnera and the skill of Tazio Nuvolari have in common with some of the most famous figures from the history of Italian literature such as De Amicis, Marinetti, Saba, Buzzati, Pratolini, Calvino and Montanelli? Seemingly nothing. But in reality, there is a world of stories, poems and texts which celebrate that special combination of sports and literature.
This is the spirit that encapsulates the theatre piece Ginnastica della letteratura italiana: a historical, literary and sporting journey through the myths, iconography and tales of sport. Luca Scarlini's tale turns sport into a social metaphor; the bicycle as a sign of freedom, boxing as a way of reinventing sad lives. From "the predominance of gymnastics on the book" (F.T. Marinetti, "Il programma politico futurista", 1913) to modern tales. Sport that tells the story of Italy. The 100th edition of the Giro d'Italia further celebrates the role of the bicycle that constitutes a literary and sporting epic. There are numerous authors who, under the aegis of the Gazzetta dello Sport, have travelled long and wide in order to report on the different champions.
Among the books and anecdotes, Scarlini's monologue traces the sporting and literary history of Italy from the end of the nineteenth century to the early 1980s. This is the spirit with which the Palestra Letteraria was created: a space where, walking between blue gymnastic mats, footballs, medals, trophies, climbing ropes and Olympic rings suspended from the ceiling, you can explore the works that best represent the union between sport and literature.
The exhibition space, containing more than 400 titles, is open to everyone and it is supported by a number of multimedia texts made available by the Biblioteca Nazionale Centrale in Florence. Visitors can consult a wide range of titles to further explore the relationship between literature and the world of sport. And it's not just limited to literature: there is a diverse musical playlist which collects some of the most famous works about the famous events in Italian sports. A synthesis between the sporting world and some of the best Italian singer songwriters to create another thought-provoking scenario, conjuring up feats from the history of the Italian sporting imagination.


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Create an Account - Increase your productivity, customize your experience, and engage in information you care about.
Dear Tallmadge Community:
We are outraged and saddened by the tragic death of George Floyd. We are all affected by this and it is long overdue that we take personal and institutional responsibility to help eliminate racism and inequality of any kind. This is a critical time for all of us who care deeply about the future of our country and our community, and we must speak out against systemic racism in the name of justice. We are seeing people around the world come together with the purpose of healing the wounds of division and hate created by racism, injustice and prejudices.
The City of Tallmadge does not tolerate racism, police brutality or discrimination within our Police Department. There are policies in place that do not permit racial profiling or discrimination, and our use of force policy is accredited through the Ohio Collaborative. There are no provisions that permit chokeholds or neck restraints and our officers are trained on de-escalation techniques. We stand behind our officers and depend on their extensive training and judicious performance when force is required to make an arrest. With that being said, we thoroughly investigate each use of force case to make sure it complies with these policies.
Moving forward we want to be even more accountable to all our citizens and we will require the daily use of body-worn cameras to increase transparency, and we will proactively review relevant policies, assess areas to be improved, and upgrade our training program to reflect those needs. We are committed to moving forward with an open mind to reforms or outside review that will increase public safety and improve our service to the community with equality for all. We welcome your input, thoughts and suggestions.
It has always been a priority within our community to be a place of positivity and unity, and to be proud of who we are, our history and our commitment to improve its future for generations. As your Mayor, I challenge each of us to look honestly within our own hearts, pray for the wisdom to change our hearts where needed and to act and speak with love and kindness to affect that change as peacemakers!
The City of Tallmadge pledges to do better – to act fairly, justly and to do our job to respect and protect all citizens of Tallmadge.
David G. KlineMayorCity of Tallmadge
Ronald WilliamsChief of PoliceTallmadge Police Department


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Concrete House
H House by Wiel Arets Architects
By admin • Dec 2, 2011 • Selected Work
Amsterdam-based studio Wiel Arets Architects has completed the H House project in 2009.
This two-story contemporary house all made of glass and concrete is located in Maastricht, The Netherlands.
Oklahoma Case Study House by Fitzsimmons Architects
By admin • Dec 2, 2011
Oklahoma City-based studio Fitzsimmons Architects has completed the Oklahoma Case Study House project in 2010.
This 1,740 square foot two story contemporary home sits on a lot with a view just outside of Oklahoma City's downtown, Oklahoma, USA.
Mont-ràs Residence by Marta Garcia-Orte and Antonio Zamora
By admin • Dec 1, 2011
Spanish architect Marta Garcia-Orte has designed the Mont-ràs Residence project in collaboration with Antonio Zamora, principal of Zamagni Zamora.
Completed in 2009, this contemporary single family home is located in Mont-ràs, a district of Palafrugell, a city in the northeast of Catalonia, Spain.
Outside In House by Takeshi Hosaka Architects
By admin • Nov 30, 2011
Japanese studio Takeshi Hosaka Architects has designed the Outside In House project for a couple and their three children.
This 1,100 square foot single-story contemporary home sits on a 1,878 square foot lot located in Yamanashi, a prefecture of Japan located in the Chūbu region of the island of Honshū.
Contemporary Bauhaus on the Carmel by Pitsou Kedem Architects
By admin • Nov 22, 2011 • Selected Work
Tel Aviv-based studio Pitsou Kedem Architects has sent us photos of the Contemporary Bauhaus on the Carmel project.
Recently completed, this 5,900 square foot two story contemporary home is located in the center of a historic avenue in Haifa's French Carmel neighborhood, Israel.
House R by CHIRST.CHRIST. Associated Architects
By admin • Nov 19, 2011
German studio CHIRST.CHRIST. Associated Architects has completed the House R project in 2010.
This 4,900 square foot contemporary residence is located in Karlsruhe, a city in the southwest of Germany.
VK1 House by Greg Wright Architects
By admin • Nov 14, 2011
South African studio Greg Wright Architects has designed the Vk1 house.
This two-story contemporary home is located in Cape Town, South Africa.
Concrete House by A-cero
By admin • Nov 13, 2011
House in Costa d'en Blanes by SANCHEZ-CANTALEJO+TOMAS
By admin • Nov 7, 2011
Palma de Mallorca-based SANCHEZ-CANTALEJO+TOMAS has completet the House in Costa d'en Blanes project in 2009.
As its name suggests, this two level contemporary home is located in Costa d'en Blanes, Mallorca, Spain.
Anil Kush Residence by Architecture Paradigm
By admin • Nov 4, 2011 • Selected Work
Indian studio Architecture Paradigm has completed the Anil Kush Residence project in 2011.
This contemporary residence sits on a 120 ft x 80 ft lot in a gated community located close to Electronic City, today's largest industrial and technology hub of Bangalore, India.
Symphony Residence by A-cero Architects
By admin • Oct 31, 2011 • Selected Work
Villa In Darvishabad by Pouya Khazaeli Parsa
By admin • Oct 21, 2011
Iranian architect Pouya Khazaeli Parsa has designed the Villa in Darvishabad project for his own wife.
Completed in 2010, this contemporary single family home is located in Darvishabad, a small village in Mazandaran Province, Iran.
1001 Nights House by A-cero
By admin • Oct 20, 2011 • Selected Work
SA Residence by Shatotto Architects
By admin • Oct 20, 2011 • Selected Work
Dhaka-based studio Shatotto Architects has sent us photos of the SA Residence project.
Completed in 2010, this contemporary home is located in Dhaka, Bangladesh.
Roncero House by ALT arquitectura
By admin • Oct 15, 2011
Spanish studio ALT arquitectura has recently completed the Roncero House project.
This two story contemporary residence is located in Madrid, Spain.
Casa La Semilla by T3Arc
By admin • Oct 10, 2011
The Open Box House by A-cero
By admin • Oct 7, 2011 • Selected Work


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EyeQue Team
November 12, 2019
If you have any form of diabetes, you could be at risk of developing eye diseases. Some conditions that can affect you are: diabetic retinopathy, cataracts, and more. In honor of Diabetic Eye Disease Awareness Month, we wanted to highlight some of the eye conditions associated with diabetes and help you find resources to test for these diseases.
Diabetics are at higher risk for developing eye diseases such as:
According to the Centers for Disease Control and Prevention (CDC), 90% of the vision loss caused by diabetic retinopathy can be prevented if it's detected early enough in an eye test. Unfortunately, less than half of people with diabetes get their eyes examined soon enough to effectively treat the disease.
The American Academy of Ophthalmology reports diabetic eye disease often won't cause noticeable symptoms right away. The AAO recommends diabetics visit an eye doctor every year for a comprehensive eye exam; during these exams, your doctor will dilate your eye and be able to spot signs of diabetic eye disease early.
EyeQue's VisionCheckBundle helps you track your vision (including visual acuity, color blindness, and more) from the comfort of your home.
However, if you are at risk for diabetic eye disease, a vision test is not enough to save you from vision loss. Only a licensed eye care professional can safely dilate your eyes and identify signs of damage to your retina, lens, or optic nerve caused by the symptoms of diabetes.
With the EyeQue Vision Monitoring Kit, you can test and track your vision. You can even share your results with your eye doctor!Buy Now


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I have lectured in art and design for many years and now tutor online. I paint the landscape around me on the borders of Wales.
Maggy has not published any blog posts yet.
Artists & Illustrators is Britain's most popular magazine for practising artists, while also being equally relevant to professionals, aspiring amateurs or to those who paint purely for pleasure.


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Clemson in Final Three for 2019 Five-Star Linebacker
**Note: Articles similar this will soon be for Premium Subscribers only: Subscribe now for just ($49.95/year) and get a free Clemson Sports Talk #CHAMP16NS shirt.**
Five-star linebacker Owen Pappoe from Loganville, GA (Grayson) has announced his final three, and Clemson made the cut along with Georgia and Nebraska. Pappoe has been a big deal for a long time and likely will be the only three-time camper at The Opening next summer.
Right now, the 6'0, 207-pound prospect says all three schools have an equal chance to land his services. It would be another considerable steal from the state of Georgia if Clemson can swing him to Tigertown. Here's why Pappoe is such a coveted prospect.
You're going to see this word pop up a lot when discussing Clemson defensive recruits. Clemson got a versatile commitment just a few weeks ago in Joseph Charleston, also from the state of Georgia, and Pappoe is another one Brent Venables would love to have. Simply put, he is a do it all guy. He can stay on the field on any down because he has the ability to drop back into coverage, he can blitz, and he can play against the run. He works well sideline to sideline and can beat quick skill position players to the edge.
As you would expect from a top linebacker prospect, Pappoe is a thumper. He loves to come off the edge and rush the quarterback on a blitz, but he's certainly not afraid by any means of tangling with a running back. He can shoot through gaps as well as he comes off the edge, stuffing the run at the line. He's just a hard-nosed ballplayer who understands the game.
This is what makes a defensive prospect elite. Pappoe diagnoses plays as well as anybody in the country, and his ability to read the offense quickly and make a decision is special. He rarely is fooled on by play-action and picks up on screen passes in a hurry. If the play is within his reach he is going to go blow it up. Sometimes he makes plays like that even when they don't appear to be within his reach.
The Bottom Line:
Pappoe is a freakish athlete, who combines that athleticism with good awareness and instincts. He would fit in perfectly for Brent Venables who loves having linebackers that can stay on the field and do it all, such as Dorian O'Daniel. Landing Pappoe would be a huge steal from the state of Georgia, as well as the rest of the country.


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Flash remake of Bubble Bobble.
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Great gunfight!
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If you like this minigolf, you will like this game.
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You against whole army ...
Lucky Balls
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Relaxing game.
Keep Ups 2
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Variation of classic Arkanoid.
Maxims day out
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Test your skill in tank battle.
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Blending work and life schedules
I used to work through lunch. By the end of the day, I'd be worn out, but I needed that hour to get through all the work that I had ahead of me… Or did I?
Remaining committed to our goals — whether it means walking away from the desk or following through to handle a customer's request — continues to build our reputation and credibility, and thus impacts our success relative to our organization and time management. I started to commit to reserving my lunch time for non-work activity. The actual time may vary each day, but I make sure that I get away.
I typically like to go for a run to clear my head, but the message here is to commit to doing what you want to do. I find that when I come back to the desk, I have a fresh perspective and new energy to drive through the rest of the day productively. Running is just one example of keeping a clear head by balancing my personal and professional needs. The key is to move your focus away from work, even for a short period of time, and to bring back a laser-focused approach upon your return. Today's professional environment and all the technology therein mean that work and life are interlaced. As much as we want to separate the two, it's almost impossible. So instead of fighting it, it's time to embrace it.
You can start by blending your personal and professional schedules together. If it's not permitted at work, then at least counterbalance them, and view them side by side to ensure that you are looking at both worlds together. Your commitment to balancing work and life will bring more control to both. Schedule your lunches, or they will never happen. Block off time for dentist appointments or they will be forgotten. Include time on your calendar needed to pick up your children from school or let the dog out so that you won't schedule one event to inadvertently create a conflict with the other.
Call (207) 594-4401 or join online at knox.villagesoup.com/join.
Donate directly to keeping quality journalism alive at knox.villagesoup.com/donate.


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US Toy Western Temporary Tattoos Reviews
US Toy Western Temporary Tattoos Lot of 144 Pieces Size: 1.5″ x 1.5″ Assorted Western/Cowboy Temporary Tattoo Design US Toy Western Temporary TattoosRead more
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Pack of 6 Plastic Red and White Checkered Tablecloths – 6 Pack – Picnic Table Covers by Oojami 6 ~ Plastic Red and White Checkered Tablecloths ~ New in sealed package. 54″ x 108″ Manufactured to the Highest Quality Available A great way to fight off stains, spills and drink rings at a party or picnic. Looking for a pack of 12 ???? Search ASIN: B07K4V2NN4 Pack of 6 ~ Plastic Red and White Checkered Tablecloths ~ […]Read more
Beistle Pin the Tail on the Cow Game | 14-Pcs Game | 1-Pack This game is full of fun for any themed party. Each game pack contains 14-Pcs. Includes: 1 Cow Picture that measures 17.25- Inches by 19-Inches Includes: 1 Blindfold Mask Includes: 12 Numbered Tails This Pin The Tail on The Cow Game a great game to play at your western themed party. You and your guests will have a fun time with this game. Each […]Read more
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About Us - Mission Statement, Community Involvement
& Charitable Donations
Plaza Salon & Spa is committed to keeping Ashland beautiful. Being a full service salon we take pride in our services and making sure you are feeling beautiful and relaxed. From 9:00 to 7:00 seven days a week, it is our goal to make sure you are taking a break from real life and are being pampered. Please feel free to call or book online to make an appointment for some much need "me" time or bring a friend to enjoy the wonderful experiences you will have! Combining our open, spacious salon and our casual atmosphere, we are known as the "friendliest spa in Ashland." We pride ourselves on being an environmentally friendly business through community involvement, green business practices, and every day resource conservation.
Kevin Huggins, owner of both Plaza Salon & Spa and Hair City, has contributed to numerous local organizations including:
Ashland Chamber of Commerce
Ashland High School Global Citizen Corp Club
Ashland High Arts Advocates (AHAA!)
Ashland High School - Senior All Night
The Bellview Benefit
Covering Young Heads to Heal Young Hearts
Friends of the Ashland Public Library
Grace Christian School
Greensprings Fire and Rescue - Volunteer fire and emergency rescue
Havurah Shir Hadash
Hedrick Middle School
Jefferson Public Radio
Kid's First - Rotary Club of Ashland Lithia Springs
Mobility Unlimited - Jazz & Jewels Auction
The Rose Circle - Mentoring for "at risk" and homeless teenagers
SOU French Club
Donations Request
To request a donation from us for your charitable organization, please refer to the contact us page and let us know a little about who you are and what you do. Thanks!


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When someone says i love you more in Sweeden
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It's as close to a Sweedwn as you'll see in Danish, at.
Not Helpful 0 Helpful 3. Hard2 said: Learn how to apologize in Swedish - fast and accurately!
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Yet, a cross-cultural relationship comes with unique challenges. Yes No. January 12, How do you say in Swedish: Or sign up using Facebook. You romantic you…!
Jag is pronounced: More by bab. Say "dig. The experience is likely to expand your world-view, which should motivate you to learn Swedish even faster. Where shall we meet? Set a time, and be sure to arrive early! Or, if you have been a couple for a while, ypu shows that you still feel the romance.
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I love you too,I miss you. It's going to be fine robbie. Rated this article: Show off your Swedish sommeone skills!|Dictionary search: Log in Register. Search titles. Search Advanced search….
Members Current visitors. Interface Language. Log in.
Swedish: I love you too,I miss you Årsta, Kalmar, Linkoping, Kungalv, Sundbyberg, Sandviken, Orebro
How do you say in Swedish: Thank you St Skovde sluts advance. No responses .]Need to translate "I love you so much" to Swedish? Here's how you say it.
mycket, fastmer, nästan, långt, Sweexen · love verb, noun More Swedish Translations.
How do you say in Swedish: "I love you too" and "I miss you"? is it moer same sound as the Icelandic "Ég" (eeg), or is it more like "Ya/eg"?.
How to Say I Love You in Swedish & Other Romantic Phrases with you", but " vara kär" can also mean to have a crush on. "Jag gillar dig" has the same meaning as "jag tycker om dig" but is a bit more colloquial.


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Bezier Segment. Clone Method
Creates a modifiable clone of this PolyBezierSegment, making deep copies of this object's values. When copying dependency properties, this method copies resource references and data bindings (but they might no longer resolve) but not animations or their current values.
System::Windows::Media::PolyBezierSegment ^ Clone();
public System.Windows.Media.PolyBezierSegment Clone ();
override this.Clone : unit -> System.Windows.Media.PolyBezierSegment
Public Function Clone () As PolyBezierSegment
A modifiable clone of the current object. The cloned object's IsFrozen property will be
false even if the source's IsFrozen property was
This method is used to produce modifiable copies of frozen Freezable objects (or any Freezable object). For convenience, this method shadows the inherited version with a strongly typed implementation.
For more information, see Freezable.Clone.


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By: Mary N. Wessling, Ph.D. ELS
Cross-Reacting Materials: The Motor Behind Conjugate Vaccines
Vaccines in history
The history and practice of vaccination as protection against viral infection is often thought to begin with Edward Jenner's discovery that cowpox, a viral infection of cows, prevented smallpox in humans. However, it had long been suspected that survivors of smallpox seemed to be immune to further infection. Attempts to induce this immunity, referred to as variolation, had likely been practiced in Africa, Asia, and China, and only introduced to Europe in the 18th century. [1] Jenner, though, can certainly be credited for his scientific, experimental approach; his inoculation of an 8-year-old boy eventually was documented in his 1798 book An Inquiry into the Causes and Effects of the Variolae vaccinae. A disease discovered in the Western Counties of England [2]. The number of lives that have been saved from misery and death is impossible to grasp; estimates of mortality from the disease before Jenner range between 30 and 35%.
What are carrier proteins, and why are they important in immunology?
Vaccines are often less effective in very young children whose immune systems are immature. For the past 35 years, vaccines have been "conjugated"—combined with a carrier protein –a cross-reactive material (CRM)–that enhances the immunogenicity of polysaccharide antigens. [3] The carrier protein CRM197 (Product #149), under consideration here, is a mutant version of Diphtheria toxin, in which the single amino acid exchange of a glycine in position 52 to a glutamic acid renders the protein non-toxic: it is one of the most widely used and highly effective carrier proteins [5]. List Labs' CRM197 has been used in a wide range of medical research, leading to a better understanding of the mechanism behind serious illnesses at all stages of the human life cycle. Most of the studies to date have employed animal models because direct research in humans would be ethically impossible.
Carrier protein CRM 197 could be used to protect premature infants from necrotizing colitis
Starting at the beginnings of life–necrotizing colitis (NEC) destroys the intestinal epithelium and is responsible for 20% to 50% of the mortality in premature infants, as well as causing significant long-term disability among its survivors. In an in vivo experiment using puppies exposed to NEC, Su et al (2013) used List's CRM 197 as an antagonist to the epithelial protective E-cadherin/b-catenin complex. Their results suggest that administration of the heparin-binding epidermal-like growth factor could protect premature babies from developing NEC, and also that it could be used in treatment of diseases resulting in intestinal injury.
List Labs' carrier protein used in Alzheimer's research
A disease that causes misery at the other end of life, Alzheimer's disease, is associated with amyloid plaques, specifically amyloid-beta, the subject of intense investigation. Vingtdeux et al (2016) in a murine study developed a novel vaccine against the pathologically relevant A-beta pE3 using List's CRM197 as a carrier protein for epitope presentation.
CRM197 carrier protein impacts humans over a lifetime
In mid-life, three of the research applications of List Labs' CRM 197 have potential for bringing health to human populations. First, heroin addiction: Jalah et al (2015) sought to develop a vaccine against heroin addiction, one that would block its biological effects by sequestering the drug in the blood, preventing it from crossing the brain barrier. The researchers used List's CRM197 along with a heroin/morphine hapten conjugate of previously established efficacy to improve its antinociceptive effects.
Another life-shortening threat, diabetic nephropathy is, in 40% of all cases, the leading cause of end-stage kidney disease. You et al (2013) injected CRM 197 in mice for 6 weeks to investigate the mechanism whereby the podocytes (cells in the Bowman's capsule that filter the blood, foot-shaped, ergo podo…) are injured. The culprit was identified as the proinflammatory M1 subset of macrophages; finding a way to attenuate the effect of the M1 macrophages on the podocytes suggests a new therapeutic approach.
And a final example: Human disease can be caused by contamination of milk products by aflatoxins—certainly a life-long concern. Researchers immunized Holstein Friesian heifers with an experimental vaccine based on the immunogen anaflatoxin B1 AnAFB1] [10]. They then studied the response to AnAFB1 conjugated with List Labs CRM197 carrier proteins to determine the efficacy of inducing antibodies specific to AFB1.
- Riedel S. Edward Jenner and the history of smallpox and vaccination. Proceedings (Baylor University, Medical Center. 2005 May; 18(1):21-5. PMCID: PMC1200696
- Lakhani S. Early clinical pathologists: Edward Jenner (1749-1823). Journal of Clinical Pathology. 1992 Sep; 45(9): 756–758. PMCID: PMC495097
- Bröker M. Potential protective immunogenicity of tetanus toxoid, diphtheria toxoid and Cross Reacting Material 197 (CRM 197) when used as carrier proteins in glycoconjugates. Human Vaccines & Immunotherapeutics. 2016; 12(3): 664-667. PMCID: PMC4964734
- Murphy K. Janeway's Immunobiology, 8th Ed. London: Garland Science, 2012:718.
- Möwinger S, Resemann A, Martin CE, et al. Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites. Scientific Reports 2016 Feb 4; 66:20488. doi: 10.1038/srep20488. PMID: 26841683
- Su Y, Yang J, Besner GE. HB-EGF promotes intestinal restitution by affecting integrin-extracellular matrix interactions and intercellular adhesions. Growth Factors. 2013 Feb; 31(1):39-55. doi: 10.3109/08977194.2012.755966. PMID: 23305395
- Vingtdeux V, Zhao H, Chandakkar P, et al. A modification-specific peptide-based immunization approach using CRM197 carrier protein: Development of a selective vaccine against pyroglutamate Aβ peptides. Molecular Medicine. 2016 Nov 28;22. doi: 10.2119/molmed.2016.00218. PMCID: PMC5263057
- Jalah R, Torres OB, Mayorov AV, et al. Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriers. Bioconjugate Chemistry. 2015 Jun 17;26(6):1041-53. doi: 10.1021/acs.bioconjchem.5b00085. PMID: 25970207
- You H, Gao T, Cooper TK, et al. Macrophages directly mediate renal injury. Am J Physiol Renal Physiol. 2013 Dec 15;305(12):F1719-27. doi: 10.1152/ajprenal.00141.2013. PMID: 24173355
- Giovati L, Gallo A, Masoero F, et al. Vaccination of heifers with anaflatoxin improves the reduction of aflatoxin B1 carry over in milk of lactating dairy cows. PLoS One. 2014 Apr 8;9(4):e94440. doi: 10.1371/journal.pone.0094440. PMCID: PMC3979841


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$158.40 $198
The Robyn Jacket is a slim jean jacket for women featuring a true vintage medium wash with placement shadows, fitted silhouette throughout, and classic chest pockets with tonal button closures. This women's jacket is designed in a body-hugging 10 oz. Japanese denim with added stretch in a luxurious cotton blend.
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 A fun run to support the LSUSD art programs. This scenic, flat and shady 2-mile race takes place around Lindo Lake's mixed media course.  Medals awarded to first through third place in multiple age groups. Â
Below are some of the highest rated restaurants in Lakeside as well as the highest rated activities in Lakeside. Extend your experience with all Lakeside has to offer.


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The Halki Diabetes Remedy Review
To reduce your chance of developing diabetes, The Halki Diabetes Remedy Review stop smoking. Smoking increases. Exercise and diet is a simple method, although Stopping smoking may result in weight gain, which raises your diabetes danger.
What is The Halki Diabetes Remedy Program?
Handle your blood sugar levels using an extra sense The Halki Diabetes Remedy Reviews of urgency in case you were diagnosed with diabetic eye disease.
Various studies have revealed that glucose The Halki Diabetes Remedy System levels that were tracked may slow worsening and down the development of eye disorder with time.
This can be important in the event that you're diagnosed with diabetes that is mild to moderate. Diabetes is a common concern in modern society, as an increasing number of individuals either have it or are in elevated risk of developing it.
To be able to keep your health up and be a great support for anybody you know who may be diabetic, it's helpful to understand a few things regarding diabetes. Continue reading for some tips.
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Try to add as legumes and lentils that you consume as you can. Cook up and toss them right into all! Herbal tea is a fantastic beverage for diabetics since it includes much terrific nourishment and may taste so good you do not even consider adding sugar or cream.
Make sure you look at the components like sugar or artificial sweeteners will be added by some producers. Supply manufacturers and drug companies have apps that may provide either supplies or a discount to you.
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It's very important to take the hints in this informative article. Ignoring the fact your diabetes is actual will make your life more complex and make it easier for other health issues to develop within your own body.
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- Now you may save 50 cents, however, the price of drugs to manage an ailment will add up to more. To maintain your palms from cracking if you assess your sugar levels, wash them using a bar of antibacterial soap.
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Leeds United: Michael Bridges reveals worrying revelation from players about Marcelo Bielsa's methods
Michael Bridges has revealed a rather worrying revelation that he has been told by some of Leeds United's senior players regarding Marcelo Bielsa's methods.
The former striker has suggested that the current group of players at the club can not quite deal with the intensity demanded from the Argentine for the duration of a season and ran out of steam at the midway point.
Speaking to the English Football Show, Bridges stated: "The other thing Leeds struggled with last year (as well as the injury to Kemar Roofe)… I was speaking to a few of players, (including) Liam Cooper the captain… they just felt after Christmas they'd almost run out of energy, the way they'd been playing football."
Indeed, it is not a difficult remark to understand and it, perhaps, hardly comes as a surprising one either.
When looking back at last season's efforts, it was rather evident that Leeds' quest for promotion was starting to falter as they suffered as they lost nine out of their 21 Championship matches following the turn of the year (Transfermarkt) despite a rather emphatic start to life under Bielsa.
Worryingly, the Whites have appeared to start in the same rich form they found themselves in the previous campaign once again, so there may be a sense of caution about just how well things are going for them at the moment.
Leeds are yet to taste defeat in the Championship after five games, having suffered their first loss in their ninth match last season.
Bielsa has also admitted recently that his side are playing with the same ideas as last season, so burnout will, indeed, have to be monitored and watched carefully – a narrative that appears to have followed the South American everywhere he has managed (iNews).
"We are playing with the same ideas as last year, but losing the ball less," he told the Yorkshire Post. "We are spending more time with the ball than without it and we are not losing the ball very easily. We are suffering less counter-attacks.
"This is the same idea of the team, but maybe with more spontaneous behaviours in the team and more natural behaviours in the team."
With a small squad of 29 players available to him (Transfermarkt) with some areas lacking important depth and his knownness for 'high-octane intensity', it would not be a surprise to see Leeds suffer a little following the festive period once again.
However, history suggests lessons can be learned from the past, so, perhaps, Bielsa will have been able to take a few notes on what went wrong (he does seem to enjoy a PowerPoint – even if he says he is not a teacher) and will be able to guide his players to the Premier League at the second time of asking.
Leeds fans, are you concerned with the remarks that have been made? Do you think the side will handle it better this season? Let us know your thoughts by sharing them in the comments section below!
Click here to comment on this articleor
Give us feedback on your Football Transfer Tavern experience


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Hospice care can be discussed at any time. Often, the discussion about hospice services takes place when the patient and his or her loved ones learn that:
- The cancer is no longer treatable and that additional therapies will not provide any benefit
- Life expectancy may be six months or less
- A physical decline and exhaustion are likely to be permanent
- Treatment is no longer desired by the patient
Many physicians hesitate to bring up the subject of hospice because they do not want patients to think that they have given up. There may come a time when you think that hospice care should be considered, but are not sure how to start this conversation. If this is the case, a member of the healthcare team can help you define what options are available.
Sometimes the patient is ready to consider hospice care before his or her loved ones are. In other cases, the family may want to start services. Often, the decision is made together by the patient and his or her loved ones. If you are struggling with the decision about hospice care, talk to a healthcare provider, oncology social worker, licensed counselor, or member of a faith-based organization about your feelings and concerns.
It is generally the patient's right to make this decision unless he or she is unable to communicate. However, if a patient cannot communicate his or her wishes, a spouse or other family member may be asked to decide. The healthcare team or an oncology social worker can help you find out what hospice care is available in your community and how to arrange for it.
In order to start hospice services, a physician must sign a "referring order" that certifies that the patient's life expectancy is six months or less if the advanced cancer runs its expected course. If a person in hospice care lives longer than six months, hospice benefits can be continued if a physician states that the person's life expectancy is still less than six months.


text:
Do VCs like short pitch decks or detailed ones?
February 24, 2020 at 10:00 PMI am monitoring my server logs to catch broken links now that I am taking years of Shopify links down (it is like playing tennis against a ball throwing machine). One of the URLs that produced a 404 error was this one: Do-interested-VCs-like-short-pitch-decks-that-stimulate-discussion-or-detailed-pitch-decks-that-demonstrate-thought-thoroughnessSomeone must have typed this question in somewhere. Let's try to answer it:I think the different types of documents are needed in different stages of the...
Tags: Google, Shopify, Peugeot, Speaking, Joris Molenaar
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The Perfect Way To Cook Fried Rice, According To Science
February 24, 2020 at 10:30 PM
Tags: Tech, KO, Georgia Tech, Royal Society Interface, Georgia Institute of Technology, Hu, Food Wine magazine, David Hu
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Bloomberg May Be Taking Hits in the Polls, But He's Crushing the Social Media Cringe Finals
February 24, 2020 at 10:35 PM
Tags: Facebook, Twitter, Elections, Science, Technology, Instagram, New York City, Social Media, Bloomberg, Nevada, 2016 Election, Michael Bloomberg, Mike Bloomberg, Pobodys Nerfect This Mess Is A Place
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Apple might launch an ARM-based Mac with its own chipset in 2021
February 24, 2020 at 11:55 PM
Tags: Apple, Startups, Mac, Intel, Ming Chi Kuo, Kuo, Plugged, Renowned Apple
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18 Easy Steps for Planning Your Next Trip
February 24, 2020 at 8:38 PM
Tags: Travel, Google, Facebook, Asia, Europe, UK, Travel Planning, Greece, Berlin, Southeast Asia, US, Colombia, Thailand, Travel Inspiration, Hawaii, Paris
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Google Penalties Can Reoccur - Your Site Is Not Immune
February 24, 2020 at 8:48 PMJohn Mueller from Google said just because a web site was once penalized, it does not mean it cannot be penalized again for the same issue. It is not like when you get a specific virus, that if you survive it, you become immune to getting that specific virus again. You can be penalized by Google for the same issue more than once.
Tags: Google, Seo, Google Search Engine Optimization, John Mueller
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How China Is Hunting Down Coronavirus Critics
February 24, 2020 at 9:02 PM
Tags: China, San Francisco, Tech, Beijing, Shanghai, WeChat, Wuhan, Ministry, Ministry of State Security, Communist Party of China, Wuhan China, Left, Joshua Left, VICE News Left
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Google Search Console Sending Email Alerts for Spikes in Search Traffic via @MattGSouthern
February 24, 2020 at 9:25 PMGoogle is sending email notifications via Search Console to alert site owners about spikes in search traffic for specific pages.The post Google Search Console Sending Email Alerts for Spikes in Search Traffic via @MattGSouthern appeared first on Search Engine Journal.
Tags: Google, Tools, News, Seo, Search Console
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Great Free Business Tools To Help Grow Your Online Business
February 24, 2020 at 9:45 PM
Tags: Google, Startups, Resources, Analytics, Business Tools, WordPress org WordPress, Google My Business Google Analytics
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Supreme Court Rejects Apple Appeal In Patent Fight With VirnetX
February 24, 2020 at 8:25 PM
Tags: Apple, Supreme Court, Washington, Tech, Vpn, Nevada, Facetime, Reuters, U S Supreme Court, Eastern District of Texas, U S Court of Appeals for the Federal Circuit, Cupertino California, John Trumpian
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Forensic Architecture redeploys surveillance-state tech to combat state-sponsored violence
February 24, 2020 at 6:38 PM
Tags: Social, TC, Gadgets, Facebook, UK, Media, Greece, Privacy, Government, Israel, US, Tech, Chicago, Pakistan, Cameroon, Amnesty International
238 people like this. Like
Revolut raises $500 million at $5.5 billion valuation
February 24, 2020 at 7:00 PM
Tags: Fundings & Exits, Startups, TC, Europe, Japan, Australia, Tech, Fintech, Revolut, Challenger Bank, TCV, Europe SINGAPORE, Revolut Metal, Nik Storonsky, Neobank, DST Global Index Ventures Balderton Capital
149 people like this. Like
Petnet's Smart Pet Feeder Goes Offline For a Week, Can't Answer Customers At All
February 24, 2020 at 7:02 PM
Tags: Tech, Customers, Ars, Petnet
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Revolut raises $500 million at a $5.5 billion valuation
February 24, 2020 at 7:00 PM
Tags: Fundings & Exits, Startups, TC, Europe, Japan, Australia, Tech, Fintech, Revolut, TCV, Europe SINGAPORE, Recent Funding, Revolut Metal, Nik Storonsky, Neobank, DST Global Index Ventures Balderton Capital
125 people like this. Like
r/NoSleep, One of the Largest Subreddits On Reddit, Goes Dark In IP-Theft Protest
February 24, 2020 at 7:45 PM
Tags: Tech, Mit, Reddit, NoSleep
136 people like this. Like
What happens when the internet vanishes?
February 24, 2020 at 7:54 PMDuring a troublesome protest or tricky election, some countries just cut the online cord.
Tags: Tech
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Google Detects Edge Users Visiting Its Sites, Urges Them to Switch to Chrome (slashdot)
February 24, 2020 at 7:21 PMIn Microsoft's Chromium-based Edge browser, Chrome's extensions "work as good as they work on Chrome browsers," argues the MS Power User blog. But guess what happens when you use Edge to visit Chrome's "Web Store" for downloading extensions? According to Google, internet users should use Google Chrome instead of Microsoft Edge if they want to use browser extensions securely. On visiting the Chrome web store on Microsoft Edge, you'll be displayed a banner with a yellow background color saying "G...
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Supreme Court denies Apple's bid to avoid paying $440 million damages in patent fight
February 24, 2020 at 7:11 PMThe United States Supreme Court on Monday dealt a blow to Apple in a decade-long legal battle over whether the iPhone maker infringed on another company's patents.
Tags: Apple, News, Supreme Court, Stories, United States Supreme Court
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US Supreme Court denies Apple's bid to avoid paying $440 million damages in patent fight
February 24, 2020 at 7:11 PMThe United States Supreme Court on Monday dealt a blow to Apple in a decade-long legal battle over whether the iPhone maker infringed on another company's patents.
Tags: Apple, Cnn, US supreme court, United States Supreme Court
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Supreme Court denies Apple's bid to avoid paying $440 million in damages
February 24, 2020 at 7:11 PMThe United States Supreme Court on Monday dealt a blow to Apple in a decade-long legal battle over whether the iPhone maker infringed on another company's patents.
Tags: Apple, News, Supreme Court, Stories, United States Supreme Court
33 people like this. Like
Intuit To Buy Credit Karma For $7.1 Billion, Creating Financial Data Giant
February 24, 2020 at 6:20 PM
Tags: Tech, Intuit, Credit Karma, Kenneth Lin, Ryan Graciano, Nichole Mustard, QuickBooks TurboTax, Sasan Goodarzi Intuit
87 people like this. Like
Would you eat a 'steak' printed by robots?
February 24, 2020 at 7:06 PM3D printing is meeting some of the ambitions touted when the technology emerged 20 years ago.
Tags: Tech
34 people like this. Like
ZX Spectrum Next, An Advanced Version of the Original 8-Bit Home Computer, Has Been Released
February 24, 2020 at 6:40 PM
Tags: Tech, Kickstarter, FPGA, Rick Dickinson, Sinclair Research They
123 people like this. Like
VC firm Oxx says SaaS startups should avoid high-risk growth models
February 24, 2020 at 6:47 PMOxx, a European venture capital firm co-founded by Richard Anton and Mikael Johnsson, this month announced the closing of its debut fund of $133 million to back "Europe's most promising SaaS companies" at Series A and beyond. Launched in 2017 and headquartered in London and Stockholm, Oxx pitches itself as one of only a few European funds focused solely on SaaS, and says it will invest broadly across software applications and infrastructure, highlighting five key themes: "data convergence & refi...
Tags: Startups, TC, Europe, London, Cloud Computing, Tech, United Kingdom, SaaS, Machine Learning, Silicon Valley, Cloud Services, Enterprise Software, Software As A Service, USP, Oxx, Richard Anton
49 people like this. Like
Major Arizona indie brokerage joins eXp
February 24, 2020 at 6:39 PMRevelation Real Estate has nearly 900 agents based out of an office in a Phoenix suburb, and had previously made investments in its brick-and-mortar operations.
Tags: Technology, Radio, Arizona, Industry News, Phoenix, Chandler, EXP, Brokerage, News Brief, Chuck Fazio, Exp Realty, Glenn Sanford, Angela Fazio, Dave Conord, Revelation Real Estate
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Mirantis co-founder launches FreedomFi to bring private LTE networks to enterprises
February 24, 2020 at 6:22 PMBoris Renski, the co-founder of Mirantis, one of the earliest and best-funded players in the OpenStack space a few years ago (which then mostly pivoted to Kubernetes and DevOps), has left his role as CMO to focus his efforts on a new startup: FreedomFi. The new company brings together open-source hardware and software to give enterprises a new way to leverage the newly opened 3.5 GHz band for private LTE and — later — 5G IoT deployments. "There is a very broad opportunity for any enterpris...
Tags: Startups, TC, Facebook, Internet Of Things, Technology, Tech, CMO, Computing, Openstack, Devops, Lte, 5g, Mobile Technology, Mirantis, Kubernetes, Open Source Hardware
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How to convert your Google Sheets files into Excel files, and edit them in Microsoft Excel
February 24, 2020 at 5:13 PM
Tags: Google, Microsoft, Trends, Lenovo, Google Photos, Google Sheets
80 people like this. Like
5 Big Marketing Lessons | What I've Learned in 23 Years of Marketing
February 24, 2020 at 5:25 PMI moved into marketing in May 1997 to become a product marketing manager at Microsoft. I didn't have any formal marketing training, but I did have in-depth knowledge of the product, having been a pre-sales consultant at Microsoft. I was fortunate to have a manager who saw my potential and was willing to invest in training me. Since then my career has followed a marketing path; even when I've managed multi-disciplinary teams, marketing has been a major part. Doubtless, the first months and years ...
Tags: Google, Budget, Microsoft, Marketing, Digital, Brand Marketing, B2b, Continental, Digital Marketing, Modern Marketing, Martech, B2B Branding, Marketing Lessons, Marketing Creativity
43 people like this. Like
Dow Drops More Than 1,000 as COVID-19 Outbreak Threatens Economy
February 24, 2020 at 5:14 PMThe Dow Jones Industrial Average slumped more than 1,000 points Monday in the worst day for the stock market in two years as investors worry that the spread of a viral outbreak that began in China will weaken global economic growth. Traders sought safety in U.S. government bonds, gold and high-dividend stocks like utilities and real estate. The yield on the 10-year Treasury fell to the lowest level in more than three years. Technology stocks accounted for much of the broad market slide, whi...
Tags: Apple, Asia, South Korea, Europe, News, Microsoft, China, Germany, Uncategorized, Markets, Nike, Bank Of America, Italy, Middle East, Treasury, Stocks
41 people like this. Like
Hydro-Quebec To Commercialize Glass Battery Co-Developed By John Goodenough
February 24, 2020 at 5:40 PM
Tags: Tech, Portugal, Daimler, Braga, University of Porto, University of Texas at Austin, John Goodenough, John B Goodenough, Hydro Quebec, Goodenough, Maria Helena Braga, Hydro Quebec To Commercialize Glass Battery Co, Karim Zaghib, Zaghib, Goodenough Braga
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AA de Majorda down CAC Cansaulim
VELSAO: AA de Majorda registered a narrow 1-0 win over CAC Cansaulim in the GFA U-14 Second Division League match at Velsao ground, on Wednesday. Ashwell Gonsalves scored the lone goal of the match. At Chicalim ground, Benfica Youth Club scored a resounding 9-0 win over Baina Sports Club. At Agassaim ground, Ponda Footballers beat Piedade Youth Association 2-1. Ponda Footballers scored through Aditya Satarkar and Johniton Mascarenhas while Tejas Nagvekar reduced the deficit for the losing side.
Maina SC edge SJD Areal, enter semis
MANDOPA: Maina Sports Club defeated Sao Jose de Areal by a solitary goal to enter the semifinals of 28th Mandopa Cup football tournament, at Mandopa grounds on Wednesday. Aleeward Mascarenhas scored the match-winning goal for Maina SC.
Goa Professional League: Velsao SCC V Guardian Angel SC, Navelim ground, 3.45 pm.
GFA U-4 League (Bardez Zone Play off Knockout): Anjuna Gymkhana V Eagles SC, Assonora ground, 4 pm.
28th Mandopa Cup (quarters): Mandopa SC V Ugem Rising Club, Mandopa grounds, 4.30 pm.


text:
|Site Notice
Marvel Ultimate Alliance 3: The Black Order
|Marvel Ultimate Alliance 3: The Black Order
Marvel Ultimate Alliance 3: The Black Order is an action role-playing game and the third title in the Marvel Ultimate Alliance series. The game was developed by Team Ninja, and was released exclusively on Nintendo Switch on July 19, 2019.
The MARVEL ULTIMATE ALLIANCE series returns for the first time in 10 years—with a new action RPG—exclusively on the Nintendo Switch™ system!
Assemble your ultimate team of Marvel Super Heroes from a huge cast including the Avengers, the Guardians of the Galaxy, the X-Men, and more! Team up with friends to prevent galactic devastation at the hands of the mad cosmic tyrant Thanos and his ruthless warmasters, The Black Order.
In this new storyline, heroes and villains unite in a race across the Marvel Universe to find the Infinity Stones before Thanos and The Black Order use them to unleash cosmic chaos. From Avengers Tower to the X-Mansion and beyond, every stop on the dangerous quest to thwart Thanos results in unexpected collisions of fan-favorite characters and iconic locations. Get closer to the action by shifting the view to an over-the-shoulder "Heroic Camera" perspective—a series first that offers a more immersive way to play single-player or multiplayer on up to four systems. Play online*, offline via local wireless, or simply pass a Joy-Con controller to a friend, so they can join your team. With another pair of Joy-Con™ controllers (sold separately), four players can team up on one system! The drop-in/drop-out co-op possibilities let players create their own "Ultimate Alliance" at will.
- Marvel Dream Teams – Assemble your dream team of Super Heroes from the Marvel Universe, each with their unique superpowers
- New Heroes – The Guardians of the Galaxy, Falcon, Scarlet Witch and more join the "Ultimate Alliance" for the first time
- Original Story – Super Heroes and Super Villains battle Thanos and The Black Order across the Marvel Universe in this new original story
- Local and Online Multiplayer – The game can be played offline or online* with up to 4 players** on a single screen or using multiple systems
- Heroic Camera – In addition to the series' traditional perspective, players can also select a dynamic, zoomed-in view, allowing for a more immersive play style for single-player or multiplayer when using multiple systems
- Multiple ways to play – Play with the Joy-Con™ controllers or the Nintendo Switch Pro Controller (sold separately)
The game features a variety of heroes teaming up to stop Thanos and his Black Order from obtaining the Infinity Stones.
Marvel Ultimate Alliance 3 is an action game that allows players to battle enemies as a variety of Marvel heroes. As characters level up, they will gain the ability to use new skills in combat. In addition to basic moves, each character also has their own "Alliance Extreme" attack.
The game features up to four player co-operative multiplayer, either local or online. Players can combine their attacks to create more powerful moves.
Technical details[edit]


text: Ron Stone, a long time resident of Seven Lakes and an avid golfer for many years realized a dream come true on Monday, October 7th. A high arcing and expertly placed 8 iron on the 126 yard, 7th hole at Seven Lakes Golf Club resulted in a HOLE IN ONE ! In the picture you can see the divot about a foot from the hole. The perfect shot was witnessed by Ed Clarke, Jim Krieder and Rheo Brouillard. Ironically, Rheo commented as the men stood on the tee box, "Someone have a hole in one so they can buy me a beer". Ron obliged.


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SAN FRANCISCO, Sept. 5 The Russians and the Communist allies made a major bid to destroy the Japanese peace treaty today and failed. View Full Article in Timesmachine »


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Social Security Disability SSI and ADHD Attention Deficit Hyperactivity Disorder. ADHD disorder can be a very debilitating disorder for both adults and children. The symptomology of ADHD is sometimes similar to those of other conditions such as borderline personality disorder, antisocial disorder,, schizoaffective disorder, and. Mar 15, 2011 · SSDI Benefits for Adults with ADHD. In addition, for an adult to qualify, if the disability began after the age of 22, he or she must have previously worked long enough and paid Social Security taxes. This definition of disability is very restrictive and allows for only those with severe limitations to qualify for SSDI.Author: Eileen Bailey.
Attention-Deficit Hyperactivity Disorder (ADHD), also known as Attention Deficit Disorder (ADD), is a chronic neuropsychiatric disorder that can affect both children and adults. The condition can range from moderate to extreme, which can interfere with an individual's ability to complete educational goals, retain a job and sustain interpersonal relationships.


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Session Information
Date: Monday, October 22, 2018
Session Title: Muscle Biology, Myositis and Myopathies Poster II: Basic and Translational Science
Session Type: ACR Poster Session B
Session Time: 9:00AM-11:00AM
Background/Purpose: Idiopathic Inflammatory Myopathy (IIM) is a group of autoimmune diseases characterized by immune-mediated injury to skeletal muscle, including polymyositis (PM) and dermatomyositis (DM). Recent studies have shown that IIM patients exhibit a type I interferon (IFN) signature, which is also present in systemic lupus erythematosus (SLE) (1). Low density granulocytes (LDG) have been identified as an important source of IFN production in SLE patients (2). Given the importance of IFN in the pathogenesis of SLE, DM, and PM, we hypothesized that LDG numbers would be increased in patients with IIM.
Methods: Healthy donors (HD) and patients with undifferentiated connective tissue disease (UCTD) were enrolled in the Hospital for Special Surgery UCTD Registry. SLE patients were enrolled in the FLARE lupus registry, and all met at least 4 of 11 ACR classification criteria for SLE. Myositis subjects in the present study were enrolled in the Hospital for Special Surgery Myositis Registry. All patients with IIM either 1) met Bohan and Peter criteria for probable or definite PM or DM, or 2) met Bohan and Peter criteria for possible PM/DM and were positive for a myositis-specific or myositis-associated antibody. PBMC were isolated from whole blood using Ficoll density centrifugation, then stained and fixed with paraformaldehyde until analyzed by flow cytometry. Cells were stained with antibodies against CD16, CD15, CD14, CD64, and CD56. LDGs were identified as cells in the PBMC fraction staining CD15hi/CD14lo. Differences between groups were analyzed using 2-tailed Student's T tests. No correction for multiple comparisons was made in this exploratory analysis.
Results: 18 patients with IIM (10 DM/8 PM), 14 healthy donors, 3 SLE patients, and 4 patients with UCTD were evaluated. The mean proportion of LDGs in IIM was numerically greater than HD, but the difference did not reach statistical significance (all presented as mean +/- standard error: 4.13% +/- 1.61 vs 0.91% +/- 0.27, p=0.104). However, when PM and DM patients were compared to HD in a subgroup analysis, DM patients had a significant elevation of LDGs (4.22% +/- 1.75, p=0.045). There was no significant correlation between strength as assessed by manual muscle testing (MMT8), or with creatine kinase levels. In accordance w/ prior studies, LDGs in SLE were elevated relative to HD (14.48% +/- 11.67, p=0.015), while the level in UCTD was closer to HD (0.61% +/- 0.14, p=0.558).
Conclusion: We did not find an increase in LDGs in PBMC of patients with IIM relative to HD, though a subgroup analysis showed DM patients exhibit a significant elevation of LDGs. Our study may not have had sufficient power to distinguish a difference in IIM patients relative to HD in the aggregate, possibly due to the heterogeneity and complexity of IIM patients. LDGs may be of importance in subgroups of IIM patients.
- Higgs BW, et al. Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis, and scleroderma share activation of a common type I interferon pathway. Ann Rheum Dis. 70, 11 (2011).
- Smith CK, Kaplan MJ. The role of neutrophils in the pathogenesis of systemic lupus erythematosus. Curr Opin Rheumatol. 27, 5, (2015).
To cite this abstract in AMA style:Fernandez D, Jia L, Olferiev M, Fernandez AM, Vega J, Merritt K, Lockshin M, Crow P. Low Density Granulocytes in Idiopathic Inflammatory Myopathy [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). https://acrabstracts.org/abstract/low-density-granulocytes-in-idiopathic-inflammatory-myopathy/. Accessed August 13, 2020.
« Back to 2018 ACR/ARHP Annual Meeting
ACR Meeting Abstracts - https://acrabstracts.org/abstract/low-density-granulocytes-in-idiopathic-inflammatory-myopathy/