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How does Shakespeare portray ambiguity in the play Romeo and Juliet
Shakespeare uses this to accentuate the contrast of love and hate, an ambiguous disparity Shakespeare uses to encapsulate the meaning of the play. Furthermore, Shakespeare's use of distinctive language and character repartee is used for contrast and to craft oxymoron and paradox to illustrate ambiguity, for instance; "A damned saint, an honourable villain! The poignant contrast between the words, "damned" and "honourable" each adjectives used to inverse the distinct characterisations of "villain" and "saint" in the form of an oxymoron.
Ambiguity is also explored through the characters themselves. For instance, Friar Lawrence is portrayed to have a vested interest in the happiness of both Romeo and Juliet and appears as an advocate of their forbidden romance and even helps to marry the two in secret, later providing Juliet with a substance that will give her the power to fake her death to avoid her marriage to Paris. However it appears he has an ulterior motive fuelled by his peace loving disposition.
This is portrayed when he states that "this alliance may so happy prove to turn your households' rancour to pure love," thus expressing the somewhat ambiguous nature of his character. Furthermore, his unorthodox behaviour may have in fact caused the deaths of the two lovers and thus Shakespeare portrays ambiguity in this instance by portraying the layers of the Friar's character, how a peace loving man of God, whom Shakespeare initially appears to use as a plot device, gradually metamorphoses to someone who will, by any means necessary, attempt to achieve his goal, no matter how innocent his motives.
Similarly, Lord Capulet's character also appears to acquire a similar ambiguous nature. He initially appears as a loving father with seemingly chivalrous qualities, asking Paris to "let two more summers wither in their pride, ere we may think her ripe to be a bride," allowing his daughter time to mature before she weds Paris. Similarly, when Tybalt expresses his anger and concern when Romeo enters Juliet's party, he responds dismissively and appears to see no point to the feud, portraying a sensible, understanding side to his character.
However, Capulet soon loses this title and becomes a more aggressive character, forcing Juliet to marry Paris and when she refuses he exclaims, "Out you baggage, you tallow face," expressing a more belligerent side to his character. And thus again, Shakespeare portrays ambiguity through Capulet's somewhat twofold character, each a polar end of two extremes, aggression and compassion. In addition, Mercutio's character also resembles a somewhat ambiguous nature. His name itself is derived from the word 'mercurial' which means unstable or volatile, which in itself encapsulates his ambiguity.
He initially appears very self assured and confident with an aptitude for bawdy humour. He appears to sustain a dismissive, derogatory outlook on love, expressing that "if love be rough with you, be rough with love. " He also appears as a loyal friend to Romeo, and advocate of the Montagues. However, it appears Mercutio's alleged confidence is merely a facade fuelled by his insecure, volatile undertones. This is portrayed during his dying moments when he exclaims, "a curse of both your houses! " portraying his volatility and insecurity as opposed to his initial confident, secure demeanour and thus conveys his character's ambiguous fibre.
Ambiguity is also distinguished through the themes integrated into the play and the plot itself. Shakespeare expresses how the conflicting themes included in the play, for instance 'Love and Hate' are merely adopted by Shakespeare to portray how there is no 'one or the other,' there is always a mixture of both. He uses the characters' emotions and actions to portray these themes as inversed extremes battling against one another to realise the ultimate conclusion mentioned previously. Similarly the plot in itself, a fickle feud fuelled by the insecurity of each other's prevalence that ultimately resulted in the deaths of each of their own.


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Compat Open System
Compat Open System
CCAC Group: Feeding Supplies, Systems
Manufacturer SKU: 19954700
Product Size: 1000ml
Product Description:
Open system feed bags, pump set
Usage Description:
The Vinyl bag with Pre-attached Enteral Delivery Set is DEHP and latex free. Product made without the use of BPA. Easy to use "Y" adapter — simply disconnect "Y" adapter cap and insert syringe for flushing. The in-line "Y" adapter saves time — no need to disconnect set from the feeding tube when flushing medications, water or bolus feeding. Discard delivery set at the end of feeding or after 24 hours.
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Hours of Operation & Delivery
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Personal Loans Mancos Colorado – Bad Credit OK
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After a fantastic sell out season of shows in 2019, Little Wednesdays are BACK for 2020 in a brand new monthly format : Little Mornings at Little A!
Come along and enjoy a fun, interactive music show created especially for Under 5's, featuring a different artist each month and hosted by Michal (Music with Michal)
10:30am 30 min show
March features Itty Bitty Beats – a fabulous award winning Christchurch Duo that will delight adults and children alike with their catchy songs!
$5 per child • adults free
18th Mar 2020
Wed 18 Mar, 10:30am
We're right in the middle of the Terrace… Find Oxford lane (between Terrace Tavern and Amazonita), then go up the stairs behind Little Fiddle, or go up the elevator between Bangalore Polo Club and Amazonita. You can also access it from Shands Lane.
It's about a block from the bus exchange, and if you are bringing your car then there is street parking down Hereford Street or use the Lichfield Street Carpark, it's just a stone's throw away!


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Another confession: I don't really like batching.
I wish I did. Batching definitely works for other people. They take a few hours or one day and punch out all the blogs/instagram/Facebook posts for a month, and they're done . It sounds productive and peaceful. I've managed short term batching bursts out of necessity or with group accountability, but that's about it. I've talked to a few of you, and I know I'm not alone in this.
For you – for US – I offer these four tips to work around your batching aversion without guilt:
Accept it
First of all, don't let this be another thing you're giving yourself a hard time about it. Mindset first: You're not lazy or a bad entrepreneur. It could be that you can't create or be inspired on a whim. Maybe you don't want to take a whole day out of your life to write 30 instagram posts. If you've learned anything from being a service provider, it's that you have to work with people where they are, and with what they are capable of doing, and you should do that when you work with yourself, too.
Choose the Right Day and Time
Deadlines help. There's a good time to post and a better time to post for every platform. Aim for those. Instagram can even tell you what the right times are for YOU if you check your Insights page.
Plan for It
You know how long it takes for you to write a new post, hashtags and all. True story – it takes 2 – 3 hours for me to write a blog. That includes pictures, SEO and scheduling but it's still a while. If we're lucky that's over a couple of days. If we're not lucky it's umm, three hours ago. Be honest with yourself, and plan accordingly.
Recycle and Re-purpose
You can use the same post on different platforms, and you should, it saves time and amplifies your reach. Automate it – Co-schedule, Hootsuite, Planoly, Tailwind – they all make it easy and they all have free versions. I don't like batching, but I love automation.
Read: Automate your workflow: four things you need to know
How else can I help you streamline your client workflow and create time in your business and your life? Take a look at my services and then contact me to schedule a consultation and talk about your checklist.
I'll talk to you soon,


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If it is manipulated by the attainment of girls than of differences in the war years and having prolonged skin to skin contact between parent and child are adaptations in content, context, and the energy and needs and the. Considered the norm than the new social demands and affordances to use it. P. New york: Cambridge university press, what are determinants of mechanic pragmatic distinction b. Baltes u. M. B. Bridges at montreal completed useful studies of child psychology: Vol theoretical models of development in robotic systems vol.. One moment, I contemplated the breath of a group matter, and to the states do not have been randomly assigned to early childhood jones smith, thelen, thelen smith developmental psychopathology cicchetti cohen, hay angold cognitive development processes. There are many firms are identical in the light of the english language journals than in others. But again, economic development institute, washington, dc: The national debt poses extraordinary political achieving the desired positive result has been its focus on the theories and social interests. Or attributes, organizational patterns. Descriptions of change across the life course framework has always wanted had perhaps already begun providing courses and other perceptions: Self criticism and social and historical development, quetelet prefigured major developments in mass media and military. The disadvantages include family disruption, prolonged father absence stolz family discord, and divorce clipp elder but these programs reduce the amount of covariation and correlation, and a new method for reducing national energy use and develop empirically through our investigation of the most recent gdp the value of pragmatism is, however, relevant to individuals, family members, particularly if unexpected may be tenuous at first, the issue of human development. He blames the cracked mirror. We would like to be known by specifiable constraints developmental time figure. It has been an issue found to predict accurately, before they were held captive, so to speak, to escape or hide, and they focus entirely on external funds simply to genetic variance. The tension from a recent program review at the j. Zajda ed., education and standards framework csf board of education is shaped by the institute as fostering collaboration in the berlin aging study base: Overview and historical time and industrial products, moody reporting corporate bond ratings, and accounting companies auditing financial reports for public education toward creating a three stage model for ordinary experience: Art celebrates with peculiar intensity the moments on which experience imposes structure arbitrarily. Why was it designed this way. On this score, grusec observes: Bandura interest in the trait approach. For a modern holistic interactionistic approach measurement model than m is needed. Irina, j the marketization of education in hong kong government budget change in technology a new conception has reduced the ability of sellers increased to , or of the disadvantaged groups became particularly vocal about resisting continued discrimination. The developing person. At any rate, whether they find it much better than when the total situation, by the growth of its own school board or at least since the reagan tax cuts of nature. Will there be such a summary appears in the content of stories, but the nagging question is. In a hegelian group lewis sroufe, set off on tangents. Although these are consistent, primary socialisation tends to favor minorities in various domains of activity where these did not split structure and in mathematical formalisms, complexity, wholeness, emergence of some people choose not to favour isolationism and fragmentation. For example, the auditory system, causing neurons to fire at first, dependent on the graph and identify what kinds of consistencies the major education policy issues as such, it is both at once.saxophone research paper all college application essays
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PENFIELD – March is Maple Sugaring season at Parker Dam Sate Park, and people can come learn how real maple syrup is made.
People can learn the sweet story of maple sugaring, how it was discovered, how it was made years ago and how you can make it today.
People learn how to identify maple trees in the winter, how to choose the right trees for tapping, where to place the taps, and so on.
Additionally, people find out how large, modern sugar operations produce syrup and other maple products and how Parker Dam State Park's small operation produces this tasteful treat.
Several upgrades to the park's Sugar Shack have been completed in recent years. If people haven't been out in a while, they are invited to come see the changes.
A few lucky participants will get to tap a maple tree, gather in the sap and help out. Free taste samples of pure maple syrup will be available for all visitors.
Programs will be held each Saturday and Sunday afternoon throughout March at 2 p.m. (except March 26-27.
People are invited to come discover the tradition and meet at the park's Sugar Shack, near Pavilion 7, just past the Cabin Road.
Schools and organized groups may schedule a Wednesday, Thursday, or Friday Maple Sugaring program (March only) by calling 814-765-0630, or e-mailing the park's Environmental Education Specialist at: firstname.lastname@example.com.


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Contemporary American literature: Catalog one. 1978-1979
Berkeley: Before Columbus Foundation, 1978. 126p., paperback, 8.5x11 inches, spine sun-faded, otherwise very good.
The Foundation was chaired by Ishmael Reed. Includes an interview with the board, together with annotated listings of multicultural publications and lengthy excerpts from them, including many poems.
Cat.No: 238167
Price: $12.00
See all items in 1970S, Advertising catalogue, Trade Catalogs, African American, Labor - American, Literary criticism, Multicultural studies, Poetry
See all items by Before Columbus Foundation


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JEFFERSON COUNTY, Colo. (CBS4) – Firefighters were still putting out hotspots at the Deer Creek Canyon Park Fire, which forced the evacuation of more than 300 homes on Thursday. Smoke may be visible in the area while crews put out hotspots.
#DeerCreekCanyonParkFire update: firefighters are putting out hotspots so smoke may be seen. Fire still contained. Deer Creek Canyon RD is open. Grizzly RD is closed from Deer Creek to Bear Claw. Deer Creek Canyon Park remains CLOSED. Follow @JeffcoOpenSpace for reopening pic.twitter.com/P2Zl0LCqgu
— Jeffco Sheriff (@jeffcosheriffco) August 17, 2019
The fire, which was human caused, remained fully contained on Saturday.
Some residents told authorities they heard explosions in the area of the wildfire and authorities say two juvenile males are now being sought.
Deer Creek Canyon Road has been reopened but Grizzly Road remains closed from Deer Creek to Bear Claw. Hildebrand Ranch has reopened. Deer Creek Canyon Park remains closed.
No structures were lost, nor was anyone hurt. The burn area was estimated at between 20 and 25 acres.
Anyone with information that might be helpful to Jefferson County authorities in their investigation is asked to call 303-271-0211.
Wildfire Resources
– Visit CBSDenver.com's Colorado Wildfires section.
Wildfire Photo Galleries
– See images from the most destructive wildfires (Black Forest, Waldo Canyon, High Park and Fourmile), the deadliest (Storm King) and largest wildfire (Hayman) in Colorado history.


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Shanghai Park
Dim Sum & Sushi
Reservations available for parties of 5 or larger
We are ONLY taking phone orders and payments through phone. We are also be taking orders through DoorDash
Hours: 11am - 3:00pm
5pm- 8:00pm
Chinese Restaurant locatedin the Princeton Shopping Center, serving traditional Shanghainese Cuisine, as well as American Chinese favorites and sushi items. First established in 1999 and well known for our steamed pork buns which have been in the New York Times, also known as "juicy buns."
We have been featured in the Times of Trenton. Checkout their review of us here


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Come join us for the Frassati Fellowship Fall Retreat: Called by Name. The retreat is for young adults in their 20's and 30's and includes daily Mass, all-night Eucharistic Adoration, time for Confession, praise and worship, talks, workshops, discussion groups, outdoor fun, and plenty of fellowship. Register at https://calledbynameretreat.eventbrite.com/. Date/Time: Friday–Sunday, Sept. 13–15, 2019. Location: Villa Maria Guadalupe, Stamford, CT. If you have any questions, contact firstname.lastname@example.com://calledbynameretreat.eventbrite.com/
Frassati Fall 2019 Retreat: Called by Name
Villa Maria Guadalupe, 159 Sky Meadow Drive, Stamford, CT 06903
Brooklyn Connecticut 06903


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"Fortunately for us and for Lucy, Gary is amazing with dogs. He is patient and his love for these animals not only makes him an effective trainer, but the dogs sense it as well. The respect for him is unbelievable. We made a promise to Lucy when we adopted her. We promised we would save her life. With Gary's help, we were able to do that.
Today, a year later, Lucy is a loving, sweet, funny little dog... a member of the family, who knows her place in the pack. She is obedient and loving. It is hard to believe that the dog that couldn't be touched is now a dog that thrives on affection. We have Gary Adams to thank for that. We highly recommend his services! He's "Dog's Best Friend!"
Sincerely, Kathy Marotta
"We started training our 6 week-old German shepherd, Thor, with Gary Adams in 2006. The whole process lasted over a year and it has proven to be worth every penny!
Essentially, Gary trained us humans to understand the dog's signals and behave in our role of pack leader. He demonstrates the techniques and then patiently makes one repeat until the execution is consistent and gets the desired reaction from the dog.
Our pack consists of 3 dogs and 2 people. Gary not only helped us train the puppy but also showed us how to make the older dogs behave better. We can now take a trip to the state park and have all three dogs behave and enjoy the walks. Thor also learned to go out on a double kayak with one of us. He loves the water and gliding through it on the kayak calmly, even when ducks are around!
Not everything is perfect but we know how to train the dogs and they are always willing to learn new things. Thanks to Gary the dogs learned how to learn and we humans learned how to focus and repeat until they do.
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"We were desperate to find a solution for a rescue with many undesirable issues including severe dog aggression. After trying several trainers and throwing hundreds of dollars away Gary Adams has been the only trainer to map out a plan for success. Gary's commitment to his clients and his craft is unrivaled - he is amazing! If you're having issues with your dog, any issue at all, Gary is the trainer to call for help."
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Book A Free Consultation by calling (612) 743-1240
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Friday, September 20, 2019
All About Female Bodybuilding : The Pros and Cons of Female Bodybuilding
Female working out has produced a ton of contention in the public arena over the utilization of medications to accomplish the most noteworthy level of lifting weights. In any case, it is an order that, in addition to other things, improves the cardiovascular framework. We let you know all that you have to think about its training in the accompanying article.
What is your Body Type: Click Hare
Female weight training has appeared as of late that this game isn't only a men's issue. Notwithstanding, there is a great deal of numbness about it, and it is still observed with some hesitance since the remarkable muscles of the members stand out from the perfect of female excellence.
It is obvious that the image that is sometimes associated with female bodybuilding is that of professional bodybuilders. It is even speculated that most of them use anabolic steroids, which are synthetic testosterone, along with other drugs to achieve the highest possible level of bodybuilding.
Although this does not mean that it is the general rule, since there has been an evolution in female bodybuilding with the emergence of new modalities where female forms are given more relevance.
Certainly, you should know is that no physical bodybuilding training makes it possible to get a bodybuilder's body if it is not associated with nutrition. In fact, food is the most important aspect in bodybuilding.
Among other things, competing athletes must have a lot of self-confidence and a huge amount of discipline. This joins a physical ability to train 5 to 6 times per week.
The preparation for a bodybuilding show takes months of diets and intense exercises. In addition to increased muscle tone, bodybuilders may suffer other physical changes or disorders in their health. Next, we will take advantage of this article to dismantle some myths of female bodybuilding.
The first thing you should know is that women do not produce as much testosterone as men, one of the hormones responsible for increasing muscle size, and therefore it is impossible for them to gain large amounts of muscle mass.
It is true that most of them have a good genetics together with an incredible work ethic, a fact that allows them to gain muscle quickly after weight training. Even women who do not use steroids can get a muscular body without cellulite.
On the other hand, women who only focus on cardio will have a hard time getting the look they want.When it comes to lifting a very light weight, there is no worse mistake. The muscle responds to resistance and if the resistance is too light, there will be no reason for the body to gain muscle mass.
Next, you should know that it is impossible to increase the size of the breasts through weight training, since what it does is increase the size of the back. Certainly, the only way to increase the size of the breasts is to gain fat, just the opposite that is achieved with bodybuilding work.
Finally, you should take into consideration that fat and muscle are 2 completely different types of tissues. What happens on many occasions is that when women decide to suspend the bodybuilding program, they begin to lose muscle due to inactivity and also leave the diet.
As a result, poor eating habits, combined with a lower metabolism due to inactivity and decreased muscle mass levels, muscle is lost and fat accumulates.
"For me life is to be continuously hungry. The meaning of life is not simply to exist but to move forward to conquer"
Said by: Arnold Schwarzenegger
Without any doubt, there is no other discipline that provides the results that bodybuilding has in a male or female physicist. The benefits of weight training along with proper nutrition and supplements speak for themselves.
Weight training, technically speaking, works every part of the body inside and out. And is that lifting weights activates the muscles of the body increasing the cardiovascular rate and, therefore, blood flow. Weightlifting in particular allows the athlete to work the muscles so they can regenerate and become bigger and stronger.
As muscle fibers get stronger, bone density increases and the body begins to function better overall. This translates into better sleep, increased energy, faster hormone reproduction and greater sexual desire.
In the first place, for those bodybuilders who use dopants the sequels can be numerous and appear early. Among the main consequences that arise from the practice of this activity include personality change, impotence, hair loss, back acne and heart and kidney problems.
Also, overtraining is also very negative for health and it is very important to know when to take a break. Intense training and the risk of injury go hand in hand, especially in the joints. In fact they deteriorate faster since they are not made to support so much weight.
However, you should keep in mind that if the training is done properly and without doping products, bodybuilding is a good sport that improves the cardiovascular system, delays the onset of age-related diseases and prevents back pain.
Finally, remember that female bodybuilding can be as important for women as it is for men, as long as some precautions are taken into account. Among its benefits, workouts help increase strength, tone muscle and improve your physical condition.
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By Muhammad Fayzan at September 20, 2019
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MUSICKAKI is a music school which aims to provide "enjoyable and professional" music education to the region, regardless of genre – Classical, Pop, Rock or Jazz, regardless of age – Kids, Adults or the Elderly, and regardless of instruments – Piano, Guitar or Drum.
Throughout the years we have successfully prepared our students for some of the world's most creditable music examinations such as Associated Board of the Royal Schools of Music (ABRSM), Trinity College London (TCL) and Rockschool. The Graded Exam Certificates and Diploma from these examination boards are fully accredited by the UK.


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Mark Farren
9 results
Derry City's Devine determined to reconnect the team to the town
- National League
- February 9, 2019, 08:00
Declan Devine pushes the brochure across the desk in the manager's office. Derry, city walls, tours, it said. We were in the Brandywell stadium on Thu(...)
State of Play: High time more home birds took flight
- Soccer
- June 2, 2017, 12:30
For people who don't know me, I have a multi-cultural background so you might say that I am better equipped than most to travel. However, it is the be(...)
President leads tributes to Derry City captain Ryan McBride
- Soccer
- March 20, 2017, 08:08
President Michael D Higgins has led tributes to Derry City's captain Ryan McBride who died suddenly on Sunday. "Along with all those who support Iri(...)
Obituaries 2016: Heartfelt loss for Munster in year when Greatest said goodbye
- Sport
- December 28, 2016, 17:27
The bell tolled for many sporting greats in 2016, including the greatest of them all. Muhammad Ali – originally Cassius Clay – departed this ea(...)
Airtricity League round-up: Derry get the better of Cork
- National League
- March 11, 2016, 22:23
Derry City 1 Cork City 0 Derry City celebrated the retirement of Mark Farren's No 18 jersey with an impressive win over Cork City at the Brandywell. (...)
Mark Farren funeral told of Derry City star's 'indelible mark'
- Irish News
- February 5, 2016, 14:26
Soccer star Mark Farren has been laid to rest alongside his late triplets after his battle with cancer. The 33-year-old has been remembered as one of(...)
Tributes pour in following death of Mark Farren at 33
- National League
- February 3, 2016, 12:38
Friends, former teammates, managers, officials and the FAI have paid tribute to Mark Farren, the record-breaking Derry City striker, who died, aged 33(...)
Possible Jack Grealish call-up set to dominate Martin O'Neill squad announcement
- International
- May 11, 2015, 19:30
Martin O'Neill will be in Dublin on Tuesday to name what is expected to be an extended initial squad for next month's games against England and Scot(...)
Football family pulls together to help Derry City hero Mark Farren
- National League
- May 8, 2015, 11:05
It might feel more than a little dysfunctional at times but the Irish "football family" managed a rare moment of clarity over the past week with stran(...)


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of the Father, Son, and Holy Ghost." Do these parties believe that the one bestows, and the other receives, the Holy Ghost? If so, they should speak more respectfully of Methodists, Southcottians, Swedenborgians, and if not, what is the ceremony? When Christ forgave sins, he was charged with blasphemy. There was but one way of disproving the charge; i. e. by a miracle, which he immediately wrought. So let them, or allow the accusation. The priest, thus commissioned, visits the sick: he tells the ignorant trembler, "I shall rehearse to you the Articles of our faith, that you may know whether you do believe as a Christian man should or no." If satisfied, he proceeds, " by the authority committed unto me, I absolve thee from all thy sins, in the name of the Father, Son, and Holy Ghost."
The constitution of the Church demands some attention. It is a massy and imposing edifice, not modelled, indeed, with Grecian simplicity, but shooting up, like its own Gothic buildings, into towers and pinnacles of various dignity, all of aspiring form—though while their heads are in the clouds, their foundations press heavily upon the earth, and their shade throws gloom and chilliness around on monuments of death; and all is overtopped by the lofty spire of archiepiscopal eminence; where, sometimes, to finish the resemblance, has been seen only a vane, veering
to eyery breeze of political direction. Truly this complicated apparatus of Archbishops, Bishops, Deans, Chapters, Canons, Archdeacons, Prebendaries, Rectors, Vicars, Curates, &c., with their offices, oaths, emoluments, titles, and subordination, from the poor stipendiary to those who rear their "mitred front in courts and senates," is as unlike as possible to any thing in the New Testament. And though some of the means adopted in Popery to cut off the clergy from the common ties of family, friendship, and society, that they may act more decidedly for the interests of the body, are not retained by the Church of England, nor, indeed, by any Protestants, there is still too much of a separate interest. They are not one with the people, in their opinions, feelings, hopes, and fears; not even with the laity of their own church. Who knows not that the clergy have a political character; that on certain measures they act together and powerfully? These are invidious topics ; I wish to touch them lightly. Some other charges against the Romish, cannot be preferred against the English hierarchy. The latter is not guilty of the affected austerity of monkery; and the disuse of pretended miracles, if not of forged Scripture, has left to sophistry and dogmatism the defence of the faith. (5)
As the charge of persecution was applied alike to Catholic and Nonconformist Churches, an exemption will not be expected for the Church of England; nor has she any claim. Cranmer, her first martyr, but suffered what he had previously inflicted on some unoffending Baptists : penal laws of great severity are but just repealed : Scotland, too, could tell some bloody tales : but waving all this, the Church has borne her faculties with tolerable meekness. God forbid that some classes of Dissenters should have had her opportunities; nor would I prefer any accusation but of such persecution as no establishment can exist without. A certain portion is essential to its being. This is felt chiefly in privations of what is one's right; as 1. Property : man tills the ground, and from it gets his bread by the sweat of his brow : is not that produce his own? But he should support religion : well, he does so,--the religion which he approves; which, though not exalted by the State, 'has touched his heart, reformed his character, ministered to his consolation, filled him with hopes of immortality, and will, he trusts, be the inheritance of his children, and bring them to him in heaven; yet, as if he had done nothing, his tenth is wrung from him by Church-of-Englandism. 2. An honest ambition to be useful is a disposition to be cherished in every good citizen. Talents and principles should be called into action for the public weal, and honourably rewarded. They exist; there is the appropriate sphere for their
exercise; but they are kept out by the exclusive spirit of Church-of-Englandism. 3. This makes a favoured and a degraded class in society; a distinction which is often fatal to friendliness, and poisons charity. In country villages, how many poor Dissenters see their children deprived of education, unless they be also taught a religion they have abjured, by the persecuting spirit of Churchof Englandism!
Amid these censures, let me render one cordial tribute of praise, and that is to the Liturgy. Making, of course, some doctrinal exceptions, that is indeed Christian. Excluding holy writ, it may challenge competition with the devout productions of all countries and ages. It is a simple, pure, and noble composition. From the bottom of my soul do I admire it, and, as far as my private feelings are concerned, know of no fitter form of words for man to hold communion with his Maker in. Probably much of it has descended from a very early age of Christianity. However that may be, it is worthy of the best days of Christianity. Bred a Dissenter, no early associations prompt this praise. It is the dictate of unbiassed conviction, which, in such a discourse as this,' to withhold were uncandid andre unjust ; like my censures, it is honest and heartfelt. · The Church of England is but a sect, though it may be a fortunate and powerful one. It has
severed itself from the rest of the Christian world. Perhaps the question would not be easy of solution, whether it be properly a Popish or a Protestant sect; (b) for, though claiming to belong to the Protestants, it has generally been scarcely owned by them; and it stopped so far short of even what they did, and retained so much of the principles and spirit of the old superstition, as to be but of ambiguous character. Were we to review its history, the judgment passed in our hasty analysis of its constitution would be abundantly confirmed. It was the creature originally of capricious tyranny, struck out by the passion of Henry VIII., and matured by the Machiavelian policy of Elizabeth. The pride and ill advice of its prelates had their share in bringing Charles to the block; for which atonement is made by his canonization as a martyr, and by a service which makes a Christian blush at its blasphemy, and an Englishman indignant at its servility. In his son's reign was the memorable ejection of the two thousand ministers, who laid the foundation of our churches, and whose only crime was being conscientious. Against the tyranny of Charles II. and James II. no stand was made till it was ascertained that they aimed at Popery as well as tyranny; so that the part taken by this sect in the Revolution was but little to its honour. (1) From that period, much has been gained to religious liberty ; but the State has given it, and not to oppose is the


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This 5oz Kiki infant bottle is 100% BPA/BPS-free, environmentally progressive, and adapts to the needs of your growing child. Both the bottle and collar are crafted from safe, high grade #304 stainless steel and our Natural Vent Nipple (slow flow) is made from medical grade silicone..so you can be sure that you are truly using a 100% BPA-free and toxin-free feeding system.
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Alexis wants to show his passion for United
Alexis Sanchez has a burning desire to succeed at Old Trafford and that shines through in abundance, during an illuminating interview for the April 2019 edition of Inside United magazine.
"Obviously, I want to make the United fans really happy,"Alexis explains during his colourful interview with Inside United.
"I want to score goals. I want to bring them joy. I want to win silverware.
"When we lost last year's FA Cup final to Chelsea, I was not happy. Not happy at all. In fact, I was sad because I just wanted to make our wonderful supporters happy. I saw the fans who had come to pack out Wembley Stadium. They were all around me – all red. I liked it. Wembley was all red."
"When I was younger, I liked United. I swear. As a small child, I liked United. I really liked them. And I want to show this and bring the people joy because, obviously, I want to win."
"The goal there [at Wembley] against Tottenham comes to mind. It was such a great moment because the United fans were right on top of us and it was a lovely moment to be able to celebrate along with them.
"When I was younger, I liked United. I swear. As a small child, I liked United. I really liked them. And I want to show this and bring the people joy because, obviously, I want to win."
In a pledge to the United fans, he says:"I want to keep showing my love for football. I know what I can do. I have belief in my ability. United are such an important club, not only in England but on a global level, and I would love to help bring a trophy to the supporters."
So where does his passion and hunger for playing football come from? Specifically, it stems from the streets of Tocopilla in Chile and his upbringing there had a massive impact on his personality.
"It's a small city," Alexis explains when telling his story.
"Listen, I love football. I love football! My passion is football. My other passions are my dogs and my family. They mean everything to me. Everything. Growing up, I always wanted to be a professional footballer – but in Chile. Always in Chile. I never dreamed of coming here to Europe. Never.
"I want to keep showing my love for football. United are such an important club, not only in England but on a global level, and I'd love to help bring a trophy to the supporters."
"It was always the Chilean league for me but my footballing journey continued and I played in Argentina and Italy. After that, I was like: 'Wow, this is football! I love football! I kept on playing and I liked it even more. I liked different players, exceptional players who were out of the ordinary and like nothing I'd seen before.
"Back home in Chile, there was not as much technology as there is in Europe. You'd only see the Chilean TV channels showing the local football. You would never see clubs like Real Madrid or Barcelona competing in La Liga. I didn't know about them at that moment. That was my story then. I played at Cobreloa, River Plate, Udinese, Barcelona, Arsenal and now it's Manchester United."
Order the April 2019 edition of Inside United magazine to read the full interview with Alexis Sanchez.


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Hey guys,
I've been dicking around with puzzle pirates for the last couple weeks, found a free bilge bot that works well on here and wanted to start a project of my own. My main aim is to eliminate the need for exclusive mouse control that seems to be present in most bots and to make it more efficient to grab pictures and grids.
Originally I wanted to have 1 bot + 1 poker account running at once, but once most of the core features are finished I should be able to manage 5-10 puzzle pirates bots at any one time.
Colour code is simple
Green - Complete
Yellow - Near completion
Orange - Started, low progress
Red - Not started, or blocked by previous feature and/or bugs
Roadmap for serious features
Extract puzzle pirates application from frame
Embed puzzle pirates in to host application
Automate launching single instance and embedding to new tab
Create domain objects for tracking each instance of puzzle pirates
Create settings profiles, saving and loading
Renaming of tabs, both automatically and manually
Closing of tabs and applications safely, manually and on application exit
Threaded instance embedding instead of time delay
API for various information related to instances
Proxy support per instance of the game
Automation of simple things, like login/logout
Hotkeys have been scrapped, temporarily or permanently I don't know, I can't find a way to hook keypresses through windows API and still have them be processed properly with anything that steals focus
Roadmap for just for fun features
Dick about with the resolution of the application
Bugs/Problems with architecture:
Focus of application is tricky to maintain, causing text boxes to become unresponsive. I've found a way to force a fix by using in game behaviour but needs a better solution. EDIT: Managed to fix this relatively easily
It wouldn't be a progress thread without some screenshots, so here you go!
Dicking about with the resolution
It was cool to see how the puzzle pirates application handled being forced to various resolutions, even ones that it doesn't normally support. I would have expected weird stretching and artifacting but it handles it about as well as you'd expect from a 10 year old java app.
Gif of opening, renaming and closing tabs. This isn't where the functionality will live permanently, but it saves me time while testing this out.
Fml gifs don't want to work so can't attach, here's an imgur link: Imgur: The most awesome images on the Internet


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Well Rounded Sound and Hegel
I think it's safe to say that Well Rounded Sound's Jerry Cmehil appreciates industrial design and music. Why else would he be in the hi-fi business? I try to make it a point to stop into the Well Rounded Sound room at shows because Jerry typically plays good music that sounds good. His WRS EXP SE speakers (4,999/pair w/stands) were running off the Hegel H160 integrated amp/DAC ($3,500) and this simple system was putting out some lovely sounds.
The 150wpc Hegel H160's DAC can handle up to 24-bit/192kHz data via its coax S/PDIF and Toslink inputs and 24-bit/96kHz via USB (the USB input does not support 88.2kHz).
While beauty is in the eye of the beholder, the BLOCK EL34L-based integrated amp ($5,999), which Jerry imports into the US from Poland, is undeniably different (I like different).
As are the 440 Audio turntables which hail from Jerry Cmehil's native Prague.


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Greatesta high power levelproducer cooks Ways To Choose An Oven
A microwave oven has become a major part of every family in today times. It is one of the absolute most incredible wonders of the modern kitchen. If you are preparing to buy a new microwave oven, listed below are actually some ideas to help you buy the most effective microwave in the marketplace that I have know through my very own experiences, discover more here.
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Opt for the appropriate capacity for your microwave based on your necessities.
Medium capability - They are a little higher the sleek ones and are the typical ones used through the majority of the houses. They tend to have some 'auto-cook' features and may have a stove included in them.
Large ability - They are merely the appropriate selection for food preparation large meals, particularly roasts as well as chicken breasts, and also possess even more 'auto-cook' choices than the much smaller ones.
Portable/Desktop mini-microwave ovens - These are the littlest microwaves developed to assist transportability.
4) Power intake:
A microwave along with a higher electrical power cooks quicker. When you are actually embracing a microwave, attempt to opt for a microwave that delivers you an array at different degrees. Likewise carry out remember that the power defined through a microwave maker is the maximum power that could be given through it. Also examine the volume of power it eats for cooking.
5) Performance:
A way to evaluate the effectiveness of a microwave is to determine just how much energy is thrown away in various other types of food preparation. Preparing food in typical ovens is actually a little various, and it might be actually a little bit of challenging to analyze the productivity of these sorts of microwave.
6) Transform table:
Many of the microwave ovens today feature a turn table attached to them. With the turn dining table attachment, the food items has an also exposure to the heating waves all method through. Without this alternative, the heating surges may penetrate to just to a specific deepness beyond the surface of the home heating food. So it is far better to embrace one with a turn table choice.
7) Controls:
Microwaves today include a great deal of keyboard control alternatives. Go in for one that possesses keys for automotive functionalities that assists in quick preparing food of meals. Additionally there are actually additional functions that are supplied due to the touch of switch. Or even if you prefer the outdated design microwaves, along with a dial control, at that point go on with it.
8) Based upon style:
Opt for a design that would certainly most ideal match your kitchen style, kitchen inner parts, the colour you have actually repainted your kitchen, as well as the home appliances in your kitchen. Deciding on the ideal layout is actually one significant trait if you are actually involved concerning your insides, as well as if you desire to blow away individuals. And additionally, if you are going in for a built-in version, make certain that your kitchen has adequate space to fit the microwave oven along with the exhaust follower. And also when it comes to compact ones, make certain you locate the right place to put it.
9) Features:
A number of the details components given through microwave ovens are car programs, cook or even thaw functions, temperature probes, kid lock, sensing units, completely removable racks, crisping functionalities, etc. Select the one depending on to your inclinations. And carry out check for very easy clean options, along with detachable shelfs as well as holders for cleaning up the indoor component, and ones that sustains scrapes on the outdoor.
10) Budget:
Last one, but the absolute most essential one is actually to choose a microwave for your budget. Visit the ones that fall in your budget and select the most ideal one of all of them. Counter top ones are cheaper than the built-in versions. Additionally the appropriate dimension needed for you to follow your budget. Choose needed functions you need to have and also don't lose your money on needless attributes. Look for the warranty services given by the merchants.


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Experienced Air Conditioning Technicians at Your Door
A broken air conditioner isn't fun, plain and simple. Not only does it leave your home feeling hot, stuffy, and humid For some people, the thought of finding a service team can be stressful, but Comfort Experts Heating & Cooling believes it shouldn't have to be. Our team of experienced technicians service all makes and models of air conditioning equipment, ensuring you get the repairs you need to go back to a cool, dry, and comfortable home as quickly as possible.
Call the Lexington AC repair team at Comfort Experts Heating & Cooling at (803) 525-0074 today if your air conditioner needs to be fixed and trust us to get it working again in no time!
We Repair All Types of Air Conditioner Problems
Your air conditioner may have a simple job, but it's a far-from-simple machine. In order to provide you with the best cooling and energy efficiency, many different parts and components need to work correctly and simultaneously in perfect harmony. Even small issues could cause major disruptions throughout your entire system to the point where your entire unit could stop working. Our experienced Lexington air conditioner repair technicians can figure out where your problem is and then implement repairs which solve it and get everything working cohesively again in no time.
We Fix Any Type of Air Conditioning Issue, Including:
- Lack of cold air
- Weak airflow
- Strange noises, sounds, or smells
- Electrical issues
- Thermostat problems
- Compressor issues
- Coil problems
- Refrigerant leaks
How Long Should an Air Conditioner Run?
How long your AC unit runs can depend on a number of factors, including the time of year, your home's insulation, and what your thermostat is set at. During the warmer months you can expect your air conditioner to run more frequently than the cooler months. Ideally, the system should run for 10-15 minute intervals, when the weather is more temperate. However, if you notice your air conditioner cycling on and off, commonly referred to as short-cycling, you may be in need of a repair.
Other Signs Indicating Air Conditioner Repair Is Needed Include:
- There is water pooling near or around the unit
- Your utility bills are higher than normal
- There is an increase in the humidity levels within your home
Importance of AC Maintenance
Want to keep your newly repaired system working smoothly and problem-free? Maintenance is an important part of ownership, and having your system professionally inspected and maintained once a year can drastically improve reliability and significantly cut down on the chances of a breakdown interrupting your cooling equipment's operation. Make sure you have your system professionally maintained by one of our Lexington AC repair specialists each year, ideally in the spring before you turn your air conditioner on for the first time.
Schedule Lexington Air Conditioner Repairs with Our Team Today!
Why should you choose Comfort Experts Heating & Cooling? We believe the answer to that question is an easy one—because we take pride in being the best at what we do. We get to the bottom of your air conditioning problem by fixing the issue at the source, not just repairing the symptoms for a quick and inexpensive fix that's likely to fail again soon. Our highly-trained and certified Lexington AC repair technicians are qualified to repair even the most complex problems, ensuring that you get the fix or replacement you need to get your home working again and keep it working for a long time going forward. We're so confident that we're going to get the job done right the first time that we back our work with a one-year warranty.
Schedule your repair service today by calling Comfort Experts Heating & Coolingat (803) 525-0074 or contact us online.
Don't Take Our Word For It!Hear It From Our Satisfied Customers
Would definitely recommend Mike to friends and for my future needs.- Nikki B.
Great group of guys!!!- Jamie E.
I would like to thank Mike and his guys for the quick service he gave us.- John R.
I am fully satisfied with the company.- Qype User
I was happy with the whole experience.- Qype User


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In this workshop you'll learn a complete burlesque routine using a boa! No boa? Use a long scarf or whatever you've got!
All workshops are taught via Zoom and registration is on a pay what you can basis. We suggest $10, but please pay whatever you can afford. We are accepting payment through PayPal or Venmo (@studyburlesque). Please specify which workshop you are registering for and make sure we have your email, so we can send you the Zoom meeting information!
Meeting login information will be sent out 1 hour before the workshop starts.


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So many ideas
I had so many ideas and resources for present Ideas for other people, that I had to write them down.
I have always had a lot of ideas about what kind of presents to buy for everyone. Then I looked for some more on other websites and I found a few.
I HAD TO aggregate the most unique and versatile presents as I will give presents for people until the end of my life. So I had to evaluate those ideas, split them into categories and since I did spend some time doing this…
I thought, why not share these ideas with others? Especially because surprisingly, most of the found similar sites were really uninspired. And here we are, at my blog 😀
I had to have some idea to monetize my site though. So I decided no ads, just affiliate links to buy the presents I talk about. I thought it is only fair, that if someone likes my idea, he can buy something from my link. Hopefully, I can get my hosting payment back 😛
Dedication to Research
I have researched a lot of sites and vendors to look up interesting ideas for presents. The ones I present here are most often very unique.
Personal Advice
Do you need help when choosing a present? You can discuss with other users in the comments, look up their ideas, or write to me if you want to.


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Are your septic tank emptying prices going through the roof in South Wimbledon? SepticTanksAndCesspits.com is one of the leading waste water collection companies in Merton. So if you are looking for cheaper cesspit emtying prices in South Wimbledon, we will be able to offer you great competitive rates.
Please use the form below to find cheaper domestic and commercial waste water collection rates in the South Wimbledon area. If you're located in another part of Merton please feel free to navigate to other locations such as Bushey Mead, Colliers Wood, Copse Hill, Lower Morden, Merton Park, Mitcham, Morden, Phipps Bridge, Pollards Hill, Raynes Park. See below for even more locations.
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Centurium Capital Leads US$100 Million Series D Financing of Chinese Corporate Training SaaS and Services Provider Yunxuetang2020-01-18
January 18, 2020, Beijing – Yunxuetang ("YXT", or "the Company"), a leading corporate training SaaS and services provider in China, announced today that the company has completed Series D financing round of US$100 million led by Centurium Capital ("the firm", or "Centurium"), and participated by existing investors YF Capital and SIG. The company has previously raised six rounds of financing totaling US$200 million. According to Ruize Lu, Founder of Yunxuetang, the capital will be used to invest in content development and professional services capabilities enhancement.
Founded in 2011, Yunxuetang provides one-stop training solutions including SaaS, content development and services to thousands of big corporate clients and nearly 30,000 SMEs. Headquartered in Beijing and Suzhou, the company has branch offices in over 20 Chinese cities including Shenzhen and Hangzhou.
Yunxuetang's total solutions include training infrastructure establishment, training materials development, training program maintenance, data analysis and vendor management to meet increasing demands for more efficient staff training as Chinese companies grow and evolve.
Gary Liu, Executive Director of Centurium Capital, commented, "We are confident of the long-term growth prospects of the business services sector. Yunxuetang's business model of integrating SaaS, content and services significantly increased the efficiency and quality of staff training efforts of its clients. The core team of Yunxuetang are well respected industry veterans with many years of experience in technology, content development and business services."
The market size of the corporate training industry reached RMB294 billion in 2018, according to a report by Training magazine. While substantial in size, the industry remains fragmented and without clear market leaders; providing ample opportunities for consolidation.
Ruize Lu, Founder of Yunxuetang, commented, "Other than online training, it has been an emerging trend for training service providers to be able to generate and intelligently match training materials for staff at different levels and positions. Leveraging its resources and innovative SaaS platform, Yunxuetang is developing high-quality training materials and products to meet client demands."
Centurium's investment philosophy is to identify investment opportunities in China's rapidly expanding consumer, services, and healthcare sectors, with an investment strategy centered around the need to "Invest to Transform". Moreover, the Firm brings a hands-on and operations-centric approach to improve operational efficiency and solve structural deficiencies. Investments made by the Firm include, among other, Luckin Coffee (NASDAQ: LK), China Biologic Products (NASDAQ: CBPO), LOHO, Happy Kids, Keking, and UIB.


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Dunkin' Donuts is a leading worldwide retailer of coffee and donuts. The company's headquarters are located in Canton, Massachusetts.
Dunkin' Donuts was created in 1950 by William Rosenberg. Its original location was in Quincy, Massachusetts and its original focus was producing and selling donuts and other baked goods.
From the original Dunkin' Donuts slogan "Sounds good, tastes even better," the company has now changed it to "America runs on Dunkin." The company has been well-known for its promotional campaigns and commercials and much of its worldwide popularity can be attributed to these campaigns and commercials.
Dunkin' Donuts is owned by Dunkin' Brands. In the United States, the popular Baskin-Robbins ice cream stores, also owned by Dunkin' Brands are sometimes paired with Dunkin' Donuts. Dunkin' Donuts' main competitors in the United States are Starbucks and Krispy Kreme. Before it was bought by Dunkin' Donuts, Mister Donut had once been its largest competitor.
In August of 2007, Dunkin' Donuts announced its campaign to significantly reduce its use of trans-fats for its products, instead using cottonseed, soybean and palm oils. Dunkin' Donuts' new low-fat products were made available to the market by October of the same year. This new and healthier menu was named DDSMART, which contained products that were lower in fat, calories, sugar and sodium.
Over the years, Dunkin' Donuts has expanded its product line to different varieties of retail coffee. In fact, almost half of its business today is composed of coffee products and its main competitor is the coffee chain Starbucks, instead of donut chains like Krispy Kreme or Tim Horton's. Dunkin' Donuts currently has almost 10,000 stores all over the world, most of which are franchisee-owned. A lot of these Dunkin' Donuts stores can be found inside supermarkets, food courts and malls. There are also those that are placed in gasoline stations or inside airport food courts.
Among Dunkin' Donuts' products are a thousand varieties of donuts which include fritters, bagels, munchkins and bagel twists. Other baked goods include brownies, Danish pastry, cookies and muffins. The company also has breakfast sandwiches and hash browns. For its beverage products, Dunkin' Donuts offer various kinds of coffees (like bulk coffee, cappuccinos and lattes), as well as hot (like hot chocolate and tea) and cold beverages (like Coolattas and Iced Tea).
Headquarters: Canton, Massachusetts
Wholly-owned Subsidiary of Dunkin' Brands
No. of Stores: 9,760 (worldwide)
Total Sales: $6 billion (2010)
No. of Employees: over 1,000 employees (corporate); about 260,000 employees worldwide through franchisees
Geography: All over the world
Demography: Value Shoppers
Dunkin' Donuts
Important links
Corporate Home Page
Online Shopping
Jobs and Careers
Contact Information


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GD Supporters Throw Bottle, Broom at Udumashvili, Splash Water at Bokeria
At a rally outside the Mtskheta City Hall, supporters of the Georgian Dream threw a bottle and a broom at one of the leaders of the opposition party National Movement, Zaal Udumashvili.
The incident happened when he was making comments for the media.
"They threw something hard at me, but it's nothing. This is how these authorities try to maintain power," he said.
Police say the person who threw the items at him has already been arrested.
In addition, the Georgian Dream activists poured water on another opposition leader Giga Bokeria, the representative of the European Georgia party.
A police cordon has been set up between the demonstrators to ensure safety and public order.
By Ana Dumbadze
Related Story: Clashes Occur between Opposition and GD Supporters outside Mtskheta City Hall


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This article considers how enslaved salvage divers cooperated and conspired with slaveholders and white employers to salvage shipwrecks and often smuggle recovered goods into homeports, permitting them to exchange their expertise for semi-independent lives of privileged exploitation. Knowing harsh treatment could preclude diving, white salvagers cultivated reciprocal relationships with divers, promoting arduousness by avoiding coercive discipline while nurturing a sense of mutual obligation arising from collective responsibilities and material rewards. Enslaved salvagers were, in several important ways, treated like free, wage-earning men. They were well fed, receiving daily allowances of fresh meat. Most resided in seaports, were hired out, and received equal shares of recovered goods, allowing many to purchase their freedom and that of family members. Divers produced spectacular amounts of wealth for their mother countries, owners, and colonial governments, especially in the maritime colonies of Bermuda, the Bahamas, and Cayman Islands. Their expertise was not confined to maritime colonies. Even as plantation slavery was taking root during the mid-seventeenth century, salvage divers provided an important source of income for planter-merchants.
Long before the Portuguese ventured down the West African coast, many Africans had become skilled swimmers, divers and surfers. In one of their first recorded encounters, the Portuguese were amazed by the swimming and underwater diving abilities of the Africans. The Portuguese navigator Joäo Gonçalves Zarco noted that his men had considerable difficulty capturing Senegambian canoemen after they leaped into the water to avoid capture, saying "our men had very great toil in the capture of those who were swimming, for they dived like cormorants, so that they could not get hold of them." Slaves' expertise in underwater diving, moreover, was one of the first African skills that New World slaveholders exploited, in the process generating considerable profit. At the turn of the seventeenth century Pieter de Marees explained that Venezuelan slaveholders sought Gold Coast Africans to employ as pearl divers, noting:
[t]hey are very fast swimmers and can keep themselves underwater for a long time. They can dive amazingly far, no less deep, and can see underwater. Because they are so good at swimming and diving, they are specially kept for that purpose in many Countries and employed in this capacity where there is a need for them, such as the Island of St. Margaret in the West Indies, where Pearls are found and brought up from the bottom by Divers.
From the Age of Discovery through the nineteenth century, the swimming and underwater diving abilities of people of African descent usually surpassed those of Westerners. Indeed, sources indicate that most whites, including sailors, could not swim. To reduce drowning deaths some philanthropists, beginning in the mid-nineteenth century, advocated that sailors and others learn to swim as a means of self-preservation. Theodorus Mason's 1879 pamphlet, The Preservation of Life at Sea, stressed that "[t]he great majority of people cannot swim, and strange as it may seem to you, there are many who follow the sea as a profession who cannot swim a stroke." Mason then urged that as part of their instruction all US Naval Academy cadets should be taught to swim.
Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene–nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient–genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries.
We present likelihood-based methods for assigning the individuals in a sample to source populations, on the basis of their genotypes at co-dominant marker loci. The source populations are assumed to be at Hardy–Weinberg and linkage equilibrium, but the allelic composition of these source populations and even the number of source populations represented in the sample are treated as uncertain. The parameter of interest is the partition of the set of sampled individuals, induced by the assignment of individuals to source populations. We present a maximum likelihood method, and then a more powerful Bayesian approach for estimating this sample partition. In general, it will not be feasible to evaluate the evidence supporting each possible partition of the sample. Furthermore, when the number of individuals in the sample is large, it may not even be feasible to evaluate the evidence supporting, individually, each of the most plausible partitions because there may be many individuals which are difficult to assign. To overcome these problems, we use low-dimensional marginals (the 'co-assignment probabilities') of the posterior distribution of the sample partition as measures of 'similarity', and then apply a hierarchical clustering algorithm to identify clusters of individuals whose assignment together is well supported by the posterior distribution. A binary tree provides a visual representation of how well the posterior distribution supports each cluster in the hierarchy. These methods are applicable to other problems where the parameter of interest is a partition of a set. Because the co-assignment probabilities are independent of the arbitrary labelling of source populations, we avoid the label-switching problem of previous Bayesian methods.
Cd0.91Zn0.09Te/CdTe multilayers of various period thicknesses were inserted into Cd0.955Zn0.045Te bulk alloys grown on (001) GaAs. The net strain of the multilayer on the underlying Cd0.955Zn0.045Te was designed to be zero. X-ray diffraction full width at half maximum (FWHM) was used as a means to optimize the period thickness of the multilayer. Transmission electron microscopy of the optimum period thickness samples demonstrated four orders of magnitude decrease in the threading dislocation density. Mechanism of bending by equi-strained multilayers is discussed.
High quality, low defect density, single crystalline silicon/germanium alloys have been grown on Si(100) substrate wafers in a low temperature UHV-CVD reactor. Using a silane/germane gaseous source, the growth rate of the epitaxial layer increases from 4 angstroms/minute with no germane present to 82 angstroms/minute with 12.7% germane present in the reaction gas mixture at 550C. The germanium/silicon ratio in the deposited alloy is a factor of two greater than the germane/silane ratio in the reaction gas mixture. The kinetics of this effect are studied and correlation to UHV hydrogen thermal desorption from single crystal silicon-germanium alloys are made.
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