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Kids and Cookies -- Appo. Activity Center
Event box
Kids and Cookies -- Appo. Activity Center
Children's Class (ages 2- 5 years) through the Appo. Activity Center. Decorate 2 cookies and engage in activities (story, songs,, simple art) related to the cookie theme. Registration is required (Go to nccde.gov) Fee is $5 per class plus an additional $5 materials fee due to instructor. Caregiver must be present.Instructor is Lina Tichenor, Pastry Chef.
For questions, call 302-378-5599.
- Date:
- Wednesday, October 2, 2019 Show more dates
- Time:
- 10:00am - 10:45am
- Location:
- Multipurpose Room II, Multipurpose Room I
- Audience:
- Babies & Toddlers Children
- Categories:
- Story Time


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The contract between Cynthia Morgan and Jude Okoye's Northside Entertainment which generated a buzz last weekend after the dancehall singer claimed it made her lose her name, Instagram account, royalties, and VEVO account has finally been released.
The contract made available to Tunde Ednut and signed in October 2013, ran for 4 years and had a 2-year option renewal. It also had a 50-50 sharing formula.
Read the contract below;

subset: commoncrawl


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Top latest Five Spring Cleaning Urban news
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Aveline ClarkeSuccess Wizards
Pieter and Peter are the opposite of lazy, and they are not your typical technical gurus. What sets them apart is their ability to break down complex human engagement processes into realistic steps and figure out how to make something more efficient and effective. This is the same with their new course: they've been able to simplify and amplify the steps to get better results as a business owner. Do yourself a favour and cut out years of figuring it out on your own: they've done it for you.
Christian WilesAutomate Today LLC
When I first heard about the "Lazy Entrepreneurs" program, I was intrigued.
Knowing Pieter and Peter for several years now and doing multiple implementation with them in the SaaS world, I can speak from personal experience regarding their integrity, their brilliance, and their work ethic.
I have known these guys to be people of their word. If they tell you something, you can pretty much take it to the bank. They know what it means to give you their word and to keep it. They do "the right thing."
Their approach to problem solving is collaborative and is expressive of their unique and combined skill sets. They each come at problems from a bit of a different vantage point. One is more "artsy and abstract" using the full-capabilities of the creative right-brained thinking, and one is more left-brained "logical and linear" diving in and tearing apart the problem to its core and building a solution that will meet the given set of criteria. I will let you figure out who is who…😊
Together, their unique giftings add to a collective powerhouse whose energy can be harnessed to solve the deepest of issues in and surrounding you and your business.Then there is grit. As uniquely different each is in their own giftings, they share a common bond, the desire to see everything there is about the matter at hand and exhaust every avenue until the matter is solved or completed. That matter can be a unique business problem, whether tech, process or people-related, it doesn't matter. Within their collective genius there is a solution and the desire to just get it done.
I highly recommend working with these guys. They are the "real deal."
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Pieter and Pete bring an irreverence to their work which is fun and refreshing, and I'm sure it also influences their 'out of the box' thinking. Expect to be stretched and challenged if you work with them, but it'll be worth the effort.
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Design for Broadleys, Windermere, for Mr A. C. Briggs
- Object:
Architectural drawing
- Place of origin:
Great Britain (made)
- Date:
1898 (made)
- Artist/Maker:
C. F. A. Voysey, born 1857 - died 1941 (architect)
- Materials and Techniques:
Pencil and watercolour
- Credit Line:
Presented by the artist
- Museum number:
- Gallery location:
Prints & Drawings Study Room, level E, case VV, shelf 2
Physical description
Design for a house, Broadleys, Windermere, showing two elevations, a cross section and a plan.
Place of Origin
Great Britain (made)
1898 (made)
C. F. A. Voysey, born 1857 - died 1941 (architect)
Materials and Techniques
Pencil and watercolour
Marks and inscriptions
1/8th scale, 2nd set
Height: 780 mm, Width: 556 mm
Object history note
Broadleys was built for the Yorkshire colliery owner Arthur Currer Briggs and his wife Helen in 1899. The house overlooks Windermere and is now home to Windermere Motor Boat Racing Club. Other designs and drawings by C. F. A. Voysey relating to Broadleys are held in the RIBA Drawings Collection. Catalogue of the Drawings Collection of the Royal Institute of British Architects: C. F. A. Voysey, Joanna Symonds, Gregg International, London, 1977, p. 45, [138].
Descriptive line
Design by C. F. A. Voysey, 'Broad Leys Windermere for A. Currer Briggs Esq', London, 1894
Bibliographic References (Citation, Note/Abstract, NAL no)
Eisenman, Stephen S., Design in the age of Darwin: from William Morris to Frank Lloyd Wright, Evanston: Northwestern University, 2008
Livingstone, Karen, Donnelly, Max and Parry, Linda 'C. F. A. Voysey: Arts and Crafts Designer', V&A Publishing, London, 2016, p.24 [17]
Subjects depicted
Buildings; Elevations (drawings); Houses; Plans (drawings)
Images Online; Designs; Drawings; Architecture
Prints, Drawings & Paintings Collection


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Join us for an amazing night in support and celebration of Senator Bernard Sanders' run for president! This event is FREE, although we are encouraging donations! We will have a "matching station" for people to match donations. Thank you so much to our artists for donating their time and energy for the cause! Musical acts performing will be:
The Immaculate Beings
Mississippi Hot Club
Willow Waters & the Earth Tones
Scoundrel Spence & GP Jacob
Funk N Spuds
Cold Sweat – MC/DJ
Visual artists will be announced soon! Join us 7pm March 2nd!


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Tobacco policy up in smoke
March 19, 2015
In the past several years, we have sat wondering exactly what the smoking policy was on campus, but up until March 11 it had seemed even SGA couldn't make up its mind.
During one of SGA's most recent meetings, it was made to seem that they, as the student government, knew better then what we do as far as what we do to our bodies.
But as luck would have it, SGA President Alex Dominguez finally listened about redoing the outdated surveys that were from three years ago.
On March 11, SGA Vice-President Jimmy Moran was outside of the campus center passing out the surveys.
With the new surveys, we can hope that it gives SGA a new direction on what the student body is wanting for the campus instead of having a bunch of senators and the dean of Allied Health and Nursing telling us what we can and can't put into our systems.
We would hope that it wouldn't just be a case of SGA basically telling us, "Hey we are the ones who know better, and you don't."
But even during the meeting that was held between the president and senators, they couldn't decide on which would be a better course of action to take.
On the new surveys, students were given three options concerning how the campus would proceed with the smoking policy. The choices were as follows: that we didn't care and smoking didn't bother us, designated areas for the smokers, or a completely tobacco-free campus.
But there seems to be more smokers than non-smokers on campus recently, and for the most part, students are following the federal law, which states that smokers need to be 20 feet from a building.
So instead of enforcing the strict tobacco-free policy on campus, designated areas seems to be the better option and way to go.
Yes, there are inspections that have to be done stating that the college put them in correctly, but it would seem a better idea than forcing students to conform to a tobacco-free policy.
The designated areas would take the smokers away from the non-smokers, and this would give the faculty a place to go as well, and not be a "headache" to the dean of Allied Health and Nursing, as she happened to put it during the meeting.
The concerning factor is that most of the senators that are currently members on the SGA board won't even be here when the roll out for this policy takes place.
So why push an issue if they won't be around to even see it through?
SGA needs to not just take into account of their views, but also ours, which we can hope that with the new surveys, they do.
But you have to wonder if we, as the student body, voice our opinion and it comes out different then what SGA thinks, will they listen to the fact that we would prefer to have the designated areas or still continue to have the policy by which federal law permits.


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Set against the backdrop of mid-west America during the late 1800s, in a small halcyon town that is magically depicted as shadowy and a host to an enumeration of deep rooted secrecy, Albert Band's Face of Fire (1959) is a ...Read More »
The Crystalline Terror of 'The Monolith Monsters' (1957) [Film Review]
Criminally undervalued by many people when discussing science fiction and horror cinema produced by Universal Studios throughout the 1950s, The Monolith Monsters (1957) would have to rate as one of the true eclectic genre gems from that wondrous decade. True, ...Read More »
A Lovecraftian Lost Gem of 1950s Cinema: The Maze (Blu Ray Review)
Older generations really get hot and bothered by millenials. They don't like our modern technology, social media, new trends, progressivism, cannabis, collapsible bicycles and most of all: Netflix. The loudest declaration from what can only be described as #BabyBoomerFilmTwitter is ...Read More »
A Love that Lasts Forever: A Ghost in the Well (1957)
Toei Studios' film output in the 1950s was a vast departure from its well-known Pinky Violence line of the 1970s. Usual Toei fare in the '50s amounted to the most part crime and samurai pictures with occasional forays outside those ...Read More »
Sound and Fury: Impotent Violence in Robert Aldrich's The Big Knife (1955)
While even most casual film noir fans seem to be acquainted with Robert Aldrich's nihilistic late, great entry in the canon, Kiss Me Deadly (1955), a noir-tinged film he made later that year with much of the same creative team, ...Read More »


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Creator of new threads from offtopic posts
Staff member
- Messages
- 398,935
- Location
- Gurugram
Get credit by responding to surveys. Sadly, not available outside USA right now.
Google Opinion Rewards - Android Apps on Google PlayAnswer quick surveys and earn Google Play credits with Google Opinion Rewards, an app created by Google Consumer Surveys.
Getting started is easy. Download the app and answer answer basic questions about yourself. About once a week you'll get a notification on your phone that a short and relevant survey is ready for you. Questions will range from, "Which logo is best?" and "Which promotion is most compelling?" to "When do you plan on traveling next?"
This is currently only available to users located in the US.
Last edited:


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Bag a Marbella night club entry pass for your hen party to skip past the queues into the hottest hangouts!
We've hand picked a selection of the most popular venues on the Costa del Sol. Simply select the club you want to hit on your night out and we'll get you on the guestlist. No wasting time wandering about or wondering where to go or how to get there; we'll make all the arrangements prior to your hen weekend.
Marbs is home to some of the hottest, trendiest and most exclusive clubs in the whole of Europe. We've joined forces with the most popular hotspots in the region and you're invited to the party!
Each venue has been carefully chosen for its style, music policy, exclusivity, drinks and atmosphere. We're talking designer decor, sweeping terraces, signature cocktails, superstar DJs, fabulous theme parties, champagne and celebrity spotting. Enjoy a legendary hen night without spending a single Euro on club entry charges!
Why queue for ages when you can stroll past the long lines, straight past the velvet rope? A must have, a entry pass will impress the girls and make the maid of honours life super simple.
Come on, girls - it's totally FREE and we make all the arrangements for you.
In a nutshell:


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Classes are on Wednesdays from 8-8.45 and are open to all who live or work at PW.... Read more »
Posts tagged as: sport
Ride with #secretcycle (and Enjoy Free Coffee!)Posted by .
It's Cycle to Work Day on Wednesday 15th August. Have a free coffee in the courtyard on beryl to celebrate!... Read more »
Clocking up the miles for charityPosted by .
PW sponsored two marathons in aid of Every Mother Counts and NSPCC. Congratulations runners!... Read more »
Safer City Cycling with LCC & BlazePosted by .
Do you cycle? Would you like to join PW's corporate membership for the London Cycling Campaign?... Read more »
Works Post Goes Bog SnorkellingPosted by .
WP joined global media teams at the World Bog Snorkelling Championships... Read more »


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$34.95 $79.99 You Save 56% ($45.04)
Complete your personal style and overall look and outfit with our Round Crossbody Bag.
When you want to look sweet and classy, our Round Crossbody Bag is perfect for you!
At Tudce, we are extremely grateful for every single customer and go above and beyond to give you the service that you deserve.
If you don't have a positive experience for ANY reason, we will do WHATEVER it takes to make sure you are 100% satisfied with your purchase.
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This is the cutest little purse ever. Perfect for trips when you don't need a big bag to carry but want to look good. Very stylish and beautifully made.
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Love this! Great quality. It can go from lunch to night on the town. It's my perfect go to bag. My LG ThinQ phone is huge and it fits great. Make-up, keys, wallet, phone and incidentals all fit fine.


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A funeral service for Ember M. (Reid) Madsen, 69, of Bettendorf, will be held at 10 a.m. Friday, Jan. 17, in the Runge Mortuary Chapel, Davenport. Burial will be in Davenport Memorial Park Cemetery. Visitation will be Thrusday, Jan. 16, from 5-7 p.m. at the mortuary.
Mrs. Madsen died Saturday, Jan. 11. 2020, at Davenport Lutheran Home.
Memorials may be made to Davenport Lutheran Home.
Online condolences may be made at www.rungemortuary.com.
A full obituary will appear in the Jan. 15 edition of The NSP.


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S- Editor Liu Y L- Editor Kumar M E- Editor Wang HF
Published online May 7, 2007. doi: 10.3748/wjg.v13.i17.2479
Revised: March 5, 2007
Accepted: March 28, 2007
Published online: May 7, 2007
AIM: To explore the capability of a monoclonal antibody (mAb) against murine endoglin to inhibit tumor angiogenesis and suppression of hepatoma growth in murine models.
METHODS: A monoclonal antibody against murine endoglin was purified by affinity chromatography and passively transfused through tail veins in two murine hepatoma models. Tumor volume and survival time were observed at three-day intervals for 48 d. Microvessels in tumor tissues were detected by immunohistochemistry against CD31, and angiogenesis in vivo was determined by alginate encapsulated assay. In addition, tumor cell apoptosis was detected by TUNEL assay.
RESULTS: Passive immunotherapy with anti-endoglin mAb could effectively suppress tumor growth, and prolonged the survival time of hepatoma-bearing mice. Angiogenesis was apparently inhibited within the tumor tissues, and the vascularization of alginate beads was also reduced in the mice passively transfused with anti-endoglin mAb. In addition, increased apoptotic cells were observed within the tumor tissues from the mice passively transfused with anti-endoglin mAb.
CONCLUSION: Passive immunotherapy with anti-endoglin mAb effectively inhibits tumor growth via inhibiting tumor angiogenesis and increasing tumor cell apoptosis, which may be highly correlated with the blockage of endoglin-related signal pathway induced by anti-endoglin mAb.
- Citation: Tan GH, Huang FY, Wang H, Huang YH, Lin YY, Li YN. Immunotherapy of hepatoma with a monoclonal antibody against murine endoglin. World J Gastroenterol 2007; 13(17): 2479-2483
- URL: https://www.wjgnet.com/1007-9327/full/v13/i17/2479.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i17.2479
Liver cancer is the 5th leading cancer type in the world[1,2]. Despite aggressive therapeutic approaches made in the past decades, the prognosis of liver cancer remains poor, 5-year mortality exceeds 95%[1-3]. It is thus necessary to seek other more rational approaches for treatment of liver cancer.
Endoglin is a homodimeric transmembrane glyco-protein, which was initially identified as a human leukemia-associated homodimer cell-membrane antigen[4]. Studies performed in different laboratories using various antibodies to endoglin have revealed endoglin expression and up-regulation in a wide range of tumor endothelia, but seldom found in the endothelia of normal tissues, suggesting that endoglin is highly related to tumor angiogenesis[5,6]. In addition, another study demonstrated that blockage of the endoglin pathway in human umbilical vein endothelial cells resulted in marked a inhibition of in vitro angiogenesis in combination with TGF-®, indicating that endoglin is a pro-angiogenic component in the endothelial cells[7]. Therefore, therapeutic approach targeting endoglin may potentially have the capability of avoiding system side-effects. It is thus conceivable to consider that passive immunotherapy with anti-endoglin mAb may potentially have the capability of inhibiting tumor growth and/or tumor metastasis through interference of the endoglin-related angiogenesis pathway. In our previous study, we have established a hybridoma cell line secreted monoclonal antibody (mAb) against murine endoglin, which has been demonstrated to have the capability of specifically staining with recombinant murine endoglin and tumor microvessel density by Western blot and immunohistochemistry[8]. In the current study, we produced and purified the mAb, and then passively transfused with the mAb in two murine hepatoma models to observe the therapeutic effects against hepatoma.
Hybridoma cell line (mEDG) secreted mAb against murine endoglin was established by us[8]. Nude mice were purchased from the Animal Center of Central South University (Hunan, China). Hepa1-6 and H22 hepatoma cell lines were presented by State Key Laboratory of Biotherapy (Sichuan University, Chengdu, China) and stored by us. BALB/c and C57BL/6 mice were purchased from the Animal Center of Hainan province, China. EMAM and RPMI-1640 culture media were purchased from Gibco (USA). CM Affi-Gel blue gel kit was purchased from Bio-Rad (USA). mAb against CD31 and labeled streptavidin biotin reagents were purchased from Dako (USA). Alginate and FITC–dextran solution were purchased from Sigma (USA). In Situ Cell Death Detection kit (AP) was purchased from Roche (USA).
The production and purification of the mAb against murine endoglin were carried out as previously described[8]. Briefly, the EMAM hybridoma cell line mEDG was cultured in complete EMAM medium supplemented with 100 mL/L fetal calf serum at 37°C in a humidified atmosphere containing 50 mL/L CO2 in air. Hybridoma cells grown at log-phase were collected and 5 × 106 cells (in 2 mL suspension) were intraperitoneally injected into nude mice. About one to two weeks later, the ascetic fluid was harvested, purified by affinity chromatography (CM Affi-Gel blue gel kit) following the manufacturer's instructions. In addition, for control observation, antibodies were also purified from the sera derived from the normal mice at 12 wk of age by affinity chromatography as previously performed by us[9].
For the investigation of the therapeutic efficacy of the anti-endoglin mAb in anti-tumor activity in vivo, mice at 6 to 8 wk of age were firstly inoculated with 2 × 106 live tumor cells into the right flank and left untreated until palpable tumors of distinct size (about 4-6 mm in diameter) appeared in the mice. Then, the mice were randomly divided into three groups of ten mice each. Group 1 (anti-endoglin mAb therapy, anti-mAb) mice were administered intravenously with the purified anti-endoglin mAb (50 mg/kg) via tail vein, and then treated twice per week for 4 consecutive weeks. Group 2 (control therapy with the purified antibodies from normal mice at 12 wk of age, cont-Ab) mice were administered intravenously with the purified antibodies (50 mg/kg) from normal mice at 12 wk of age via tail vein, and then treated twice per week for 4 consecutive weeks, as did in group 1. Group 3 (untreated control, cont-NS) mice were injected with equal volume of normal saline (NS) without containing any antibodies. The Hepa1-6 hepatoma (Hepal-6) model was established in C57BL/6 mice, and the H22 hepatoma (H22) model was in BALB/c mice. All procedures were performed in accordance with protocols approved by the Institutional Animal Care and Use Committee. The tumor size and survival rate were monitored at a three-day interval, and the tumor volume was calculated by the following formula: Tumor volume = 0.52 × length × width2.
To determine microvessel density (MVD), frozen sec-tions of tumor tissues were prepared, and subjected to immunohistochemical staining for CD31 as previously described[9-12]. Briefly, frozen sections were fixed in acetone, incubated, and stained with an antibody reactive to CD31. Sections were then stained with labeled streptavidin biotin reagents. Any endothelial cell or endothelial cluster positive for CD31 (purple staining) was considered to be a single countable microvessel.
Alginate-encapsulated tumor cell assays were performed as previously described[13]. Briefly, Hepal-6 or H22 hepatoma cells were resuspended in a 15 g/L sodium alginate solution and added dropwise into a swirling 37°C solution of 250 mmol/L calcium chloride. Alginate beads were formed containing approximately 1 × 105 tumor cells per bead. Mice were anesthetized, and four beads were subcutaneously implanted into an incision made on the dorsal side. Incisions were closed with surgical clamps. Thereafter, mice were grouped and treated with antibodies or NS as aforementioned. After 14 d, mice were injected intravenously with 100 μL of 100 mg/kg FITC-dextran solution. Beads were surgically removed and FITC-dextran was quantified against a standard curve of FITC-dextran as previously described[9-12].
To detect in situ tumor cell apoptosis, sections of tumor tissues from both Hepal-6 and H22 models were fixed with 10 g/L paraformaldehyde in PBS, and apoptotic cells were detected using TUNEL assay according to the manufacturer's instructions (In Situ Cell Death Detection kit, Roche, USA). Apoptosis rate was quantified in a blind fashion by two independent reviewers by determining the percentage of positively stained cell nuclei in 20 randomly chosen fields/section at 200 × magnification.
For comparison of individual time points, ANOVA and an unpaired Student's t-test were used. Kaplan-Meier method was used to plot survival curves and the statistical significance was determined by the log-rank test. P < 0.05 was considered statistically significant. Error bars represent the SD (standard deviation) unless otherwise indicated.
The tumor volume was monitored at a three-day interval. Tumors in both Hepal-6 (Figure 1A) and H22 (Figure 1B) models grew progressively in two control group mice treated with normal antibodies or NS, but a significant inhibition of tumor growth was observed in the mice passively transfused with anti-endoglin mAb (Figure 1). Compared with the control groups, tumor volume in the mice passively transfused with anti-endoglin mAb significantly decreased (P < 0.05) from d 21 or 24 after tumor cell injection (Figure 1).
The survival rate of the tumor-bearing mice was also monitored at a three-day interval. Compared with the control group mice treated with normal antibodies or NS, the survival rate of the mice passively transfused with anti-endoglin mAb significantly increased in both Hepal-6 (Figure 2A) and H22 (Figure 2B) models (P < 0.01 by log-rank test). Thus, significant increase in survival rate and inhibition of tumor growth in the two hepatoma models suggested that passive immunotherapy with an anti-endoglin mAb has significant therapeutic effects against murine hepatoma.
Significantly more microvessels (purple color staining) were seen in the tumor tissue sections from the control mice (Figures 3B and C), while almost no such stained microvessels were seen in the tumor tissue sections from the mice passively transfused with anti-endoglin mAb (Figure 3A). The average number of microvessels per high-power field in both Hepal-6 and H22 hepatoma models (10.32 ± 3.51 and 12.85 ± 4.27, respectively) in the mice passively transfused with anti-endoglin mAb were significantly lower than those in the mice transfused with control antibodies (89.69 ± 15.06 and 80.56 ± 15.38, respectively) and the mice transfused with NS (89.12 ± 16.31 and 94.35 ± 17.89, respectively) (Figure 3D; P < 0.001).
Inhibition of angiogenesis was further confirmed by using alginate encapsulation assay. Alginate implanted angiogenesis was quantified by measuring the uptake of FITC-dextran into beads. Compared with the two control groups (Figures 4B and C), a significant inhibition of angiogenesis was found on the beads from the mice passively transfused with anti-endoglin mAb (Figure 4A). FITC-dextran uptake (μg) was significantly decreased in both Hepal-6 and H22 hepatoma models (0.42 ± 0.07 and 0.51 ± 0.09, respectively) in the mice passively transfused with anti-endoglin mAb than that in the mice transfused with control antibodies (4.38 ± 0.94 and 4.79 ± 1.28, respectively) and the mice transfused with NS (4.56 ± 1.02 and 4.93 ± 1.15) (Figure 4D; P < 0.001).
To further investigate the anti-tumor mechanism induced by the passive transfusion with anti-endoglin mAb, a TUNEL assay was performed to observe the tumor cell apoptosis in situ. TUNEL assay revealed a marked increase in apoptosis in tumor tissues from both Hepal-6 and H22 hepatoma models (43.68% ± 7.32% and 39.54% ± 5.93%, respectively) in the mice passively transfused with anti-endoglin mAb than that in the mice transfused with control antibodies (8.43% ± 2.37% and 7.18% ± 1.96%, respectively) and the mice transfused with NS (9.02% ± 3.02% and 6.95% ± 2.39%, respectively) (Figure 5; P < 0.001).
The generation of new blood vessels, or angiogenesis, is a complex multi-step process. Evidence suggests that the growth and persistence of solid tumors and their metastases are angiogenesis-dependent[14-17]. To date, a number of molecules that stimulate angiogenesis as well as those that inhibit this process have been elucidated[17,18]. In this regard, as a strategy for cancer therapy, anti-angiogenic therapy, which targets genetically stable endothelial cells, has several advantages over conventional tumor cell targeting in the therapy of solid tumors: (1) This approach may have the potential to circumvent the problem of acquired drug resistance[19,20]. The reasonable explanation is that drug resistant mutants are easily generated from tumor cells due to the genetic instability of tumor cells. On the contrary, genetically stable normal cells, such as vascular endothelial cells, would be far less adept at generating such mutants; (2) anti-angiogenic therapy may have the capability of overcoming the problem of tumor heterogeneity[21]. At present, tumor heterogeneity has become a major problem with the tumor cell-targeting therapy; (3) physiological barriers for the high-molecular weight drugs (such as antibodies and immunoconjugates) to penetrate into solid tumors will be also circumvented by targeting a tumor's vasculature rather than tumor cells themselves[22,23]. The possible reason is that, unlike tumor cells in the solid tumors, the vascular endothelial cells are directly accessible to circulating high-molecular weight drugs; (4) many thousands of dependent tumor cells will die of nutrient and/or oxygen deprivation if a capillary or a sector of the capillary bed fails[24,25]. Therefore, killing of only a minority of vascular endothelial cells of tumors may be sufficient to eradicate most malignant cells in tumor tissues; and (5) a single agent developed for anti-angiogenic therapy could be applied to various types of solid tumors and other angiogenesis-associated diseases.
A few lines of evidence have demonstrated that endoglin is one of the marker molecules of tumor angiogenesis, and is specifically expressed and up-regulated in tumor-associated angiogenic vasculatures, specially in tumor microvessels[1-3]. The level of endoglin in serum and tumor tissues detected by ELISA or immunohistochemistry correlated well with the prognosis of solid tumors[2,3,26]. Thus, a specific mAb against endoglin may be a good tool for diagnosis and treatment of solid tumors, including hepatoma.
In the current study, we used an anti-endoglin mAb established by us in our previous study to observe the anti-tumor activities by passive immunotherapy in two hepatoma models. We found that passive immunotherapy with anti-endoglin mAb could effectively suppress tumor growth, and prolong the survival rate of hepatoma-bearing mice. Angiogenesis was apparently inhibited within the tumor tissues, and the vascularization of alginate beads was also reduced in the mice passively transfused with anti-endoglin mAb. In addition, there were increased apoptotic cells within the tumor tissues from the mice passively transfused with anti-endoglin mAb. Based on the aforementioned findings, we may thus conclude the possibility that the therapeutic activities against hepatoma by passive immunotherapy with anti-endoglin mAb may result from the inhibition of tumor angiogenesis and the increase of tumor cell apoptosis, which may highly correlate with the blockage of endoglin-related signal pathway induced by anti-endoglin mAb.
The endothelium in normal vasculatures is considered the most quiescent because the turnover of the endothelial cells is very low[27-30]. However, the endothelial cells in the tumor tissues can undergo rapid proliferation which promote spurts of tumor angiogenesis due to hypoxia and secretion of various molecules that stimulate angiogenesis by the endothelial cells themselves and tumor cells. Therefore, a proliferation-associated antigen on endothelial cells may be a good candidate for anti-angiogenic therapy. Endoglin has been proven to be a proliferation-associated antigen on endothelial cells[7,31,32]. Previous studies demonstrated that anti-endoglin mAbs showed a highly restricted reactivity to proliferating endothelial cells, immature acute lymphoblastic leukemia (ALL) cells and myeloid/monocytic leukemia cells[4,33,34]. In the current study, we further found that passive immunotherapy with anti-endoglin mAb reached effectively anti-hepatoma activities in murine models. Thus, this study also demonstrated that passive immunotherapy with anti-endoglin mAb may be a potential approach for treatment of hepatoma and other solid tumors.
|Pisani P, Parkin DM, Bray F, Ferlay J. Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer. 1999;83:18-29. [PubMed] [DOI]
|Parkin DM. Global cancer statistics in the year 2000. Lancet Oncol. 2001;2:533-543. [PubMed] [DOI]
|Gougos A, Letarte M. Identification of a human endothelial cell antigen with monoclonal antibody 44G4 produced against a pre-B leukemic cell line. J Immunol. 1988;141:1925-1933. [PubMed]
|Fonsatti E, Sigalotti L, Arslan P, Altomonte M, Maio M. Emerging role of endoglin (CD105) as a marker of angiogenesis with clinical potential in human malignancies. Curr Cancer Drug Targets. 2003;3:427-432. [PubMed] [DOI]
|Duff SE, Li C, Garland JM, Kumar S. CD105 is important for angiogenesis: evidence and potential applications. FASEB J. 2003;17:984-992. [PubMed] [DOI]
|She X, Matsuno F, Harada N, Tsai H, Seon BK. Synergy between anti-endoglin (CD105) monoclonal antibodies and TGF-beta in suppression of growth of human endothelial cells. Int J Cancer. 2004;108:251-257. [PubMed] [DOI]
|Li YN, Tan GH, Jiao JG, Huang FY, Jiang J. Establishment of a monoclonal antibody against extracellular domain of murine endoglin. Zhongguo Xiandai Yixue. 2007;17:1-4.
|Tan GH, Wei YQ, Tian L, Zhao X, Yang L, Li J, He QM, Wu Y, Wen YJ, Yi T. Active immunotherapy of tumors with a recombinant xenogeneic endoglin as a model antigen. Eur J Immunol. 2004;34:2012-2021. [PubMed] [DOI]
|Wei YQ, Huang MJ, Yang L, Zhao X, Tian L, Lu Y, Shu JM, Lu CJ, Niu T, Kang B. Immunogene therapy of tumors with vaccine based on Xenopus homologous vascular endothelial growth factor as a model antigen. Proc Natl Acad Sci USA. 2001;98:11545-11550. [PubMed] [DOI]
|He QM, Wei YQ, Tian L, Zhao X, Su JM, Yang L, Lu Y, Kan B, Lou YY, Huang MJ. Inhibition of tumor growth with a vaccine based on xenogeneic homologous fibroblast growth factor receptor-1 in mice. J Biol Chem. 2003;278:21831-21836. [PubMed] [DOI]
|Jiao JG, Li YN, Wang H, Liu Q, Cao JX, Bai RZ, Huang FY. A plasmid DNA vaccine encoding the extracellular domain of porcine endoglin induces anti-tumour immune response against self-endoglin-related angiogenesis in two liver cancer models. Dig Liver Dis. 2006;38:578-587. [PubMed] [DOI]
|Hoffmann J, Schirner M, Menrad A, Schneider MR. A highly sensitive model for quantification of in vivo tumor angiogenesis induced by alginate-encapsulated tumor cells. Cancer Res. 1997;57:3847-3851. [PubMed]
|Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst. 1990;82:4-6. [PubMed] [DOI]
|Wickham TJ, Haskard D, Segal D, Kovesdi I. Targeting endothelium for gene therapy via receptors up-regulated during angiogenesis and inflammation. Cancer Immunol Immunother. 1997;45:149-151. [PubMed] [DOI]
|Gupta MK, Qin RY. Mechanism and its regulation of tumor-induced angiogenesis. World J Gastroenterol. 2003;9:1144-1155. [PubMed]
|Paleolog EM. Angiogenesis: a critical process in the pathogenesis of RA--a role for VEGF? Br J Rheumatol. 1996;35:917-919. [PubMed] [DOI]
|Kerbel RS. Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents. Bioessays. 1991;13:31-36. [PubMed] [DOI]
|Boehm T, Folkman J, Browder T, O'Reilly MS. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature. 1997;390:404-407. [PubMed] [DOI]
|Matsuno F, Haruta Y, Kondo M, Tsai H, Barcos M, Seon BK. Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodies. Clin Cancer Res. 1999;5:371-382. [PubMed]
|Dvorak HF, Nagy JA, Dvorak AM. Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies. Cancer Cells. 1991;3:77-85. [PubMed]
|Denekamp J. Review article: angiogenesis, neovascular proliferation and vascular pathophysiology as targets for cancer therapy. Br J Radiol. 1993;66:181-196. [PubMed] [DOI]
|Thorpe PE, Burrows FJ. Antibody-directed targeting of the vasculature of solid tumors. Breast Cancer Res Treat. 1995;36:237-251. [PubMed] [DOI]
|Thorpe PE. Vascular targeting agents as cancer therapeutics. Clin Cancer Res. 2004;10:415-427. [PubMed] [DOI]
|Folkman J, Shing Y. Angiogenesis. J Biol Chem. 1992;267:10931-10934. [PubMed]
|Auerbach W, Auerbach R. Angiogenesis inhibition: a review. Pharmacol Ther. 1994;63:265-311. [PubMed] [DOI]
|Engerman RL, Pfaffenbach D, Davis MD. Cell turnover of capillaries. Lab Invest. 1967;17:738-743. [PubMed]
|Risau W. Differentiation of endothelium. FASEB J. 1995;9:926-933. [PubMed]
|Burrows FJ, Derbyshire EJ, Tazzari PL, Amlot P, Gazdar AF, King SW, Letarte M, Vitetta ES, Thorpe PE. Up-regulation of endoglin on vascular endothelial cells in human solid tumors: implications for diagnosis and therapy. Clin Cancer Res. 1995;1:1623-1634. [PubMed]
|Seon BK, Matsuno F, Haruta Y, Kondo M, Barcos M. Long-lasting complete inhibition of human solid tumors in SCID mice by targeting endothelial cells of tumor vasculature with antihuman endoglin immunotoxin. Clin Cancer Res. 1997;3:1031-1044. [PubMed]
|Haruta Y, Seon BK. Distinct human leukemia-associated cell surface glycoprotein GP160 defined by monoclonal antibody SN6. Proc Natl Acad Sci USA. 1986;83:7898-7902. [PubMed] [DOI]
|Rokhlin OW, Cohen MB, Kubagawa H, Letarte M, Cooper MD. Differential expression of endoglin on fetal and adult hematopoietic cells in human bone marrow. J Immunol. 1995;154:4456-4465. [PubMed]


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Writing Center: Cram Jam Session
Come join the Writing Center in their Cram Jam Session!
The Writing Center tutors will be hosting a study session on Thursday, Dec. 7, from 6-10 p.m. in the Writing Center to help with any last minute assignments or studying. They will have various tutors available on hand.
Snacks, games and fun will also be provided.


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24 April 2017
Netscientific announces that BTG plc has purchased Wanda's shares in OncoVerse for next stage of development
("NetScientific" or the "Company" or the "Group")
London, UK – 24 April 2017 – NetScientific Plc (AIM: NSCI, "NetScientific", "the Group"), the transatlantic healthcare IP commercialisation Group, announces that its portfolio company Wanda has sold its holding in OncoVerse LLC ('OncoVerse' or 'the Company') to BTG plc ('BTG') for an undisclosed amount.
The sale represents a strong return on NetScientific's initial investment and a successful exit from the first downstream application from Wanda, validating Wanda's superior ability to provide support for clinicians.
OncoVerse is a digital health platform designed to allow cancer patients' care teams to collaborate and allow clinicians across all disciplines to work together to determine the most effective treatment plan for their patients.
OncoVerse was initially conceived by a Dignity Health physician and two administrators, who wanted a tool to improve team collaboration, especially when evaluating complex cancer cases and determining the appropriate treatment plans for patients. Dignity Health, one of the nation's largest health care systems, prototyped and tested the platform internally and then partnered with Wanda to further develop the software. Dignity Health has also been a co-investor in the joint venture since the platform's inception and will continue to be a shareholder alongside BTG.
NetScientific's equity in OncoVerse comes from its majority shareholding in Wanda.
"We believe the OncoVerse platform will become a leading tool in the management of cancer patients and we are proud to have been involved in helping bring it to maturity. The sale of the equity to BTG represents a strong return on NetScientific's initial investment, and underscores Wanda's unique expertise in creating tools which can support informed treatment decisions. We are continuing to work with Wanda to support the company in the development of remote health management tools and sophisticated data analysis and to identify other promising opportunities to maximise investment returns from the technology."
François R. MarteletChief Executive Officer of NetScientific and Chairman of Wanda
"I am very proud of the team at Wanda for creating such a valuable product, in collaboration with Dignity Health, which helps improve quality of care for cancer patients. BTG's expertise and partnership will enable a strong path forward for Oncoverse and its mission. We at Wanda will continue focusing on building modern and innovative clinical solutions to enhance management of care for patients."
Foad DabiriCEO of Wanda
For more information, please contact:
François R. Martelet, M.D., CEO Ian Postlethwaite, CFO
Tel: +44 (0)20 3514 1800
Stifel Nicolaus Europe Limited (NOMAD and broker)
Jonathan Senior/ David Arch/ Ben Maddison
Tel: +44 (0)20 7710 7600
Consilium Strategic Communications
Mary-Jane Elliott / Jessica Hodgson / Chris Welsh / Laura Thornton
Tel: +44 (0)20 3709 5700
About NetScientific Plc
NetScientific is a transatlantic healthcare technology group with an investment strategy focused on sourcing, funding and commercialising technologies that significantly improve the health and well-being of people with chronic diseases. For more information, please visit the website at www.netscientific.net
About Wanda
San Francisco-based Wanda is dedicated to advancing the effectiveness and efficiency of medicine by using machine learning in place of conventional technologies and by enabling clinicians to make more informed care decisions. Wanda recognizes that remote monitoring and algorithms cannot save lives or reduce hospitalizations unless the individual and their caregivers are promptly informed and highly engaged. Through the collaboration of data science and applied medical research, Wanda has proven that its inline analytics predict preventable events much better than conventional methods. Wanda serves as a diligent companion, providing encouragement and intelligent visual guidance that simplifies and improves lives, while simultaneously helping organizations reduce their care delivery costs. Wanda is a NetScientific portfolio company. More information about Wanda can be found at www.yourwanda.com.
About BTG
BTG is a global specialist healthcare company bringing to market innovative products in specialist areas of medicine to better serve doctors and their patients. We have a portfolio of Interventional Medicine products to advance the treatment of cancer, severe emphysema, severe blood clots and varicose veins, and Specialty Pharmaceuticals that help patients overexposed to certain medications or toxins. Inspired by patient and physician needs, BTG is investing to expand its portfolio to address some of today's most complex healthcare challenges. To learn more about BTG, please visit: btgplc.com.
About Dignity Health
Dignity Health, one of the nation's largest health care systems, is a 22-state network of more than 9,000 physicians, 62,000 employees, and 400 care centers, including hospitals, urgent and occupational care, imaging centers, home health, and primary care clinics. Headquartered in San Francisco, Dignity Health is dedicated to providing compassionate, high-quality, and affordable patient-centered care with special attention to the poor and underserved. In FY16, Dignity Health provided $2.2 billion in charitable care and services. For more information, please visit www.dignityhealth.org.


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Mini Briefcase Business Card Case
Jump in the sack with your business cards!
Victim of my own success.
Will be back
We offer various options for delivery. You can see them all in your shopping cart.
97% of parcels reach our customers on time. We make every effort to ensure a timely delivery.
If ordered before 22:55
Product Description
If you want to come across like a true professional, you won't be able to do without business cards. But where do you put them? In your back pocket or inside pocket is not very comfortable and what's even worse, there's a chance that they'll end up in the washing machine and ruin your clothes. So, what could be handier or more professional than a special case to keep the business cards in? At your next big meeting, conference or congress you can put your flair to use to unlock the 2 locks on this cool case and take out your business cards.
The mini Briefcase Business Card case is an aluminium case to neatly store your business cards in. And you will be ahead of the competition as soon as you open the case up on the table. Made of aluminium, blocks RFID scanners in case you want to keep your bankcards in it.
- Looks like a suitcase with tonnes of cash, only smaller
- Aluminium construction blocks RFID scanning
- Material: Aluminium
- Can hold approximately 20 business cards
Dimensions: 10cm (L) × 6.5cm (W) × 1.6cm (H)


text:
Learning set FAHREN LERNEN MAX
Get your learning set FAHREN LERNEN MAX from our customer care at your Rausch Driving School.
We ensure that the learning package FAHREN LERNEN MAX strictly follows the test requirements.
Success guarantee1
Prepare yourself for the theory test by the learning package FAHREN LERNEN MAX. In case you fail the theory test you will receive a voucher 50,- €.
Content learning package:
- Guaranteed all exam questions including videos for your theoretical exam. Guaranteed!
- Personal Online Trainer available in 12 different languages2
- Success guarantee1
- App for your smartphone
- Examination simulations
- App Drivers Cam! Difficult traffic situations from your exam area
- With the practice packages you can driving lessons prepare and follow up
- Text book for offline moments
- Theory lessons as audio book
- Display your balance from your driving school account
Advantages learning package:
- Guided learning path - achieving your driving license in 4 learning steps
- Always up to date - question changes are automatically inside
- PC, MAC, iPhone, iPad, Android Smartphone and Tablet - the Personal Online Trainer will adapt to your level
- Link to practical lessons by practice packages - and therefore less driving lessons
- Effective Learning - Same questions will not be asked again and again
- Learning aids for different levels are offered for each question
- The Personal Online Trainer identifies your deficiencies and offers individual training
- The system sticks to your level of training
1 If you do not pass the theoretical exam with success, we guarantee you a voucher over 50, - €. The success guarantee is granted only for the first failed theory examination. Prerequisite: learning the learning set max has been released in your driving school Rausch and the status light in your learning program on the day of your theoretical exam is green. The traffic light turns green when you have completed 15 successful test exams in a row in the last 10 days. The additional TÜV fee is not covered. Only in the driving school Barerstr. 49, Schleissheimerstr. 115, Ungererstr. 118a
Each voucher is deducted from the practical test. Cash payment is not possible. The voucher is not transferable. In case of loss of a voucher no replacement possible. Voucher only available and valid in the following driving schools: Barerstr. 49, Schleißheimerstr. 115, Ungererstr. 118a
2 German, English, French, Greek, Italian, Polish, Portuguese, Romanian, Russian, Serbo-Croatian, Spanish, Turkish
Your prerequisites
- Minimum age 17,5
- Documents for application for a driver´s license
- Theoretical and practical training
- Theoretical and practical exam
Your vehicle
For your safety and enjoyment in the training you drive on top equipped vehicles latest models. A professional maintenance and cleanliness of our vehicles is natural for us.
The training must take place on a car with a manual transmission.
After passing the exam, you can also drive cars with automatic transmissions.
At locations you will find following training vehicles that are offered in the respective driving school.
- Drive easy simulator
- BMW 116d
- VW Golf 1.6d
- VW Golf Sportsvan 1.6d
- VW Polo 1.6d
Your duration of training
The training duration depends on the following factors:
- required number of driving lessons
- taken driving lessons per day/ week
- taken theory lessons per week
- license application processing time
Crash course individual
We will arrange your individual practical crash course. As intense as you want. You decide the duration of the crash course and you can even choose your individual timetable for your practical lessons. You can attend our theory lessons 5 days a week. Theory you can start every time.
Before your crash course starts, it is necessary to do an application for a driver´s license at your local driver´s license agency.
Our customer care of your Rausch driving school can tell you what a forerun we currently need for your crash course. They gladly plan your driver´s license with you.
Participating driving schools:
Barerstr. 49
Schleißheimerstr. 115
Ungererstr. 118a
Crash course car 11
Car license in 11 days. This crash course starts at fixed times. More information at Crash Course CAR 11
Your theory
Theory lessons
Number theory lessons with no prepossession a drivers license:
- 12 double lessons (at 90 minutes) of basic knowledge
- 2 double lessons (at 90 minutes) especially for licenses class B
Number theory lessons at a pre-owned drivers license:
- 6 double lessons (at 90 minutes) of basic knowledge
- 2 double lessons (at 90 minutes) especially for licenses class B
Your driving lesson
The driving lessons consist of practice lessons and special lessons.
Our driving instructors provide a pleasant atmosphere in smoke-free cars.
Punctuality is taken for granted in our school.
We see it as our duty to provide everything we can that you enjoy your driving lessons.
The special lessons are made at the end of the training.
Mock exams will prepare you for the real test. They show you what to expect in the test and your instructor whether you are ready for the test.
Training lesson
At the training lessons you practice basic tasks and cityride.
The number of your training lessons is adaptable.
Always according to our motto: "As much as necessary, as little as possible!"
In order to guarantee the ideal number of lessons for you, we will keep an individual training schedule.
DriversCam - Video analysis of difficult traffic situations
So you can be better prepared for your practical exam, we offer you the DriversCam.
With the videos of DriversCam, you will understand the most important and most difficult traffic situations, which can be reactivated in your practical test. Comfortable and stress-free you watch at home or on your Smartphone the videos. You can find situations exclusively from your test area in Munich.
Including app. DriversCam is available in English.
To use DriversCam, you will need the learning set FAHREN LERNEN MAX.
DriversCam currently only in following driving schools available:
Barerstr 49, Schleißheimerstr. 115, Siegfriedstr. 25, Ungererstr. 100


text:
Navy: India expels Chinese research vessel
India has expelled a Chinese research ship for entering the Indian waters without permission, allegedly for research activities.
The Chinese research vessel Shi Yan-1 was in India's exclusive economic zone in September near Andaman islands when Indian surveillance teams spotted it. The officials asked the crew to leave Indian waters immediately.
'Our stand is that if you have to work in our Exclusive Economic Zone, then you have to take our permission,' Navy Chief Admiral Karambir Singh said here on Tuesday, confirming the incident. He was addressing a press conference ahead of the Navy Day.
Singh said Indian Navy kept a close watch on the movement of Chinese ships and submarines in the Indian Ocean as 6-8 Chinese vessels were present in the region at any point of time.
China and Pakistan are scheduled to hold an exercise in the north Arabian Sea next year for which their vessels will have to pass through the Indian Ocean region.
Announcing the joint exercise in Beijing last week, the Chinese Ministry of Defence spokesperson Col Ren Guoqiang said PLA Navy would send five ships including destroyers, frigates and submarine rescue vessels for the exercise.
On why China was not invited for the Milan 2020 exercise in Vishakhapatnam in which 41 nations would participate, Admiral Singh said only those nations were called for drill with whom Indian Navy had exercised in the past and established an interoperability framework.
'With China, we have not done even a PassEx (Passage Exercise),' he said. Asked whether a bilateral exercise between Indian and Chinese PLA Navy would happen in the future, he quipped, 'Its a question above my pay grade.'


text:
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- Nursing Praxis
Clinical Nurse Specialist - Rural Generalist (Kaikoura)on 30 July
Clinical Nurse Specialist - Rural Generalist
- Rare full-time, permanent role with our team at Kaikoura Health Te Ha o Te Ora
- Highly skilled Clinical Nurse Specialist with a diverse background of experience including Acute care
- Diverse role working across both primary and secondary care
Our Purpose: Why we do it
When you work with the Canterbury District Health Board, you're part of something very special. We plan, fund and deliver health services to the almost 600,000 people that live in the Canterbury region. Our primary goal is to put people at the heart of everything we do.
The Team: What we do
This is a rare role within our team at Kaikoura Health Te Ha o Te Ora as a CNS within the specialty of Rural Generalist. This is a diverse and varied role where you will be working across the health system but focusing on aged, primary and secondary care. This would be an ideal role for a skilled CNS who is looking to work within a truly rural generalist role.
The Role: Where you fit in
In this role, you will be responsible for:
- providing expert nursing knowledge across the organisation
- providing clinical nursing leadership to the broad range of health, community and professional groups
- have a passion for further education and upskilling of other nurses.
Your skills will include the following:
- Excellent assessment skills and ability to prescribe advanced nursing therapeutics.
- Ability to guide, support and lead staff across a variety of different areas
- Outstanding interpersonal and relationship building skills
- High level of personal integrity and professionalism
Our Culture: What matters to us
Ko ngā tāngata, te mātua mahi
Putting people at the heart of all we do
Health is ultimately all about people. What's important around here is the way we care for and respect others, the responsibility taken for delivering outcomes, and going about our work with integrity.
Belonging Here: Becoming part of our story
Being part of the Canterbury District Health Board, you will enjoy a fantastic benefits scheme, the opportunity for flexible working arrangements and ongoing focus on your career development.
The Canterbury DHB believes that diversity and inclusion is key to ensure we deliver the best care for our diverse population. The Canterbury DHB is an inclusive and equal opportunity employer that welcomes and respects everyone.
If this role has sparked your interest but does not match your skills then please visit our careers website and have a look at our roles that better suit your expertise.
Please apply online or to discuss further becoming part of our team, please contact: Simon Liddy
Email: email@example.com
Phone: 027 839 5946
Closing Date: 23 August 2020


text:
Stasie's Galactic Starfighter Guide (Ships, Components, Crew, Tips)
View Single Post
Advice from GSF Veterans:
How to pick an All-Star Team.
Optimizing Crew Passive and Active Abilities
Thanks to Verain, Armonddd, and Stasie for editing and content contributions.
Updated for SWTOR 5.5 (provisional)
KotFE Content Bug Warning
If you participate in KotFE story content you will loose access to class characters for your character's class, and also to HK-51 and Treek as GSF crewmembers. At present the only way to access them again is to spend another 1250 fleet requisition on unlocking each one again. By all means submit a bug report about this, but don't expect action anytime soon (ie, the next 2-3 years).
There is a partial workaround to this, if the class companion is a currently equipped crew member, it will be grayed out as a "locked" cremember, but the passive and active abilities will still work. So if you equip your preferred crewmembers before starting KotFE content, and are ok with never switching them again, then you won't really be affected by the bug.
Kinda sucks if you're a Consular that likes to switch between Bypass and Wingman though.
/ End Bug Warning
Crew are important in GSF. Crew let you access active abilities that can be as powerful as the actives from major component slots. In most cases by picking carefully, you can also get a set of passive bonuses that are similar in magnitude to what's provided by a major component slot.
To optimize crew choices, you'll probably have to spend some fleet requisition to unlock some crew members, but the nice thing is that you don't have to unlock all of them. Half or a bit less should let you get ideal options for every ship in GSF.
If it seems too complicated, don't worry. The default selection is not optimal for all ships, but it is good enough for all ships.
For my convenience, this is all based on Republic crew options, there are a few differences on the Imperial side in terms of arrangement of abilities, but for the most part it's not a problem to pick up the same sets of actives and passives for a ship type on either faction.
As a general disclaimer, I'd like to point out that the documentation for GSF is pretty sparse. In cases where tooltips might have more than one plausible interpretation, there's usually no official information to resolve what they really mean. This guide mostly reflects the conventional wisdom of experienced GSF pilots, just keep in mind that there's always the possibility that we're wrong. If you see inconsistencies in tooltips or between what tooltips say and what seems to happen in game, I encourage you to make a forum thread about it. The developers do read threads about possible bugs, and if the bugs are confirmed they may be fixed at some point.
Passive Abilities
Why start with passives? They're always on, so they never suffer from lack of optimal employment on the player's part, assuming that a good choice was make when picking crew.
Passive abilities are also easier to optimize. Actives can be as much a matter of personal preference and playstyle as anything else, while with passive abilities there are more clearly best matches between sets of passives and particular ship builds or components.
Offensive Crew Passive Abilities
Improved Kill Zone
: Firing Arc Increased by 2 degrees.
This basically makes the firing circle for your weapons larger. For weapons affected by accuracy, meaning all primary weapons, railguns, and rocket pods the amount of benefit this offers depends on how high the weapon's tracking penalty and base accuracy are. For any missile weapon with a range over 5000 m, it's quite good because their firing arcs aren't that big, and a bigger circle makes it easier to acquire missile locks. If you look at the effect on the ship data sheet, you find that the increase is measured from the center, but the total arc is measured from edge to edge. So if the base weapon arc in the tooltip is 24, this passive will increase it to 28, because 2 degrees are added to each side.
Recommended for
: long range missiles. For other weapons figure out accuracy penalties before taking this. If your chance of hitting at the outside of the circle is low, then it's not worth taking. Also provides less relative value for weapons that already have wide firing arcs.
Weapon accuracy increased by 6%.
Does what it says. This helps overcome the target's evasion. It also helps counteract weapon tracking penalties. Works on weapons with an accuracy rating such as blasters, rockets, and railguns. No benefit to mines, missiles and drones.
Recommended for
: Gunships, Strikes, and Scouts all find this to be an almost mandatory pick. It's not bad for Bombers either, but they tend not to get quite as much out of it.
Rapid Reload:
Secondary weapon reload and cooldown times reduced by 8%.
Reduces reload times for missiles, including proton and thermite torpedoes. Miniscule reduction in railgun GCD.
Despite the fact that they are secondary weapons it does not appear to reduce the cooldowns or reload times for mines.
Recommended for:
Spare Ammo:
Ammo capacity increased by 25%.
Increases ammunition of secondary weapons that use ammo: missiles, torpedoes, and rockets.
Recommended for
: Ships that do much of their damage with ammo using weapons AND frequently run out of ammunition for them. Scouts using cluster missiles with double volley upgrade or rocket pods are good examples. Pike/Quell if the pilot runs out of missiles on a regular basis.
Defensive Crew Passive Abilities
Power to Shields:
Shield power pool increased 10%
Pretty good on any ship that uses shields as it's primary defense.
Recommended for:
Ships that have shields.
Quick Recharge:
Shield regeneration increased 15%
Given the regeneration rates of most ships this is not that great. You need long periods out of combat for it to have a significant effect. It's possible I missed some rarely taken component combination that makes it really good, but for the most part seems inferior to other options.
Recommended for:
none at present, could change if regen stacking becomes possible and good at some point in the future.
Response Tuning
: Evasion increased by 5%.
Decreases chance that weapons with an accuracy attribute will hit your ship. Excellent for ships that have multiple components with evasion available, good for all other ships.
Recommended for:
Scouts, type 1 Gunships. Ok for any ship with at least some evasion. One of the best overall defensive options.
Not recommended for
: type 2 gunships, evasion likes company and type 2 gunships have no evasion available except the crew passive, Bombers also typically don't take evasion components and may not want this passive.
Structural Support:
Damage Reduction increased by 9%.
Reduces hull damage taken by 9%. All sources of hull damage reduction are treated as armor based damage reduction. That means that weapons that ignore armor, ignore all damage reduction. While it is possible to stack damage reduction on some ships, armor piercing weapons are so common that it's not a popular choice.
Recommended for:
Flying through minefields. In general this means minelayers and T3 strikes that are intended for use in an anti-bomber role in domination games. There are a few pilots that favor it in other cases, but the widespread occurrence of armor piercing weapons reduces it's value significantly compared to other choices.
Tactical Crew Passive Abilities
Comm Boost:
Communications range increased 5 km.
Improves your ability to share sensor data with teammates, making spotting enemies easier.
Recommended for:
Any ship.
Depth of Field:
Sensor Focus range increased 2.5 km
Sensor focus is a cone in front of your ship where sensors can detect enemies. It extends to a greater distance than sensor radius. This passive extends the cone another 2.5 km. Helps find targets at a longer range.
Recommended for
: Gunships, scouts, strikes can all get some use from this, probably a bit less valuable for bombers.
Peripheral Vision:
Sensor radius increased 2.5 km. Increases detection of enemies in all directions by 2.5 km, but does not extend sensor focus range.
Recommended for
:All ships. A more defense minded option than sensor focus.
Silent Running:
Sensor dampening increased 4 km.
Decreases range that enemy sensors can detect you by up to 4 km, if they can detect you at ranges greater than 15 km. Between comm ability and sensor damping being inactivated at a range of 15km this ability went from a must have to almost never taken. Still potentially quite dangerous in the hands of a skilled pilot with a ship build and flying style designed to maximize the element of surprise this can give. See thread posts 66-68 for details.
Recommended for
:Nostalgic gunship pilots, people who want to hide from opponents more than 15 km away.
Engineering Crew Passive Abilites
Efficient Maneuvers:
Engine component abilities, maneuvers and boosting cost 13% less engine power. Good choice for most ships.
If you don't use boost much and don't use engine abilities much you
not need it.
Recommended for:
All ships.
Efficient Fire:
Cost of using blasters reduced by 13%.
Doesn't work for railguns or other secondary weapons.
Recommended for
: Ships with blasters that draw lots of energy.
Power to Blasters:
Increases blaster power pool 15%.
Recommended for:
Gunships, ships that have high draw blasters.
Power to Engines
: Increases engine power pool 15%.
More energy for boosting. Can help make a ship less likely to be fully drained of engine power by ion weapons.
Recommended for
: Ships that want to boost a longer distance.
"A padawan's master sets their Jedi trial, Rajivari set mine."
- Zhe Lian, Sage.


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Another study has found eating too fast may lead to weight gain and metabolic syndrome.
In a recent study published in BMJ Open, researchers looked at 60,000 patients, analyzing their BMI and waist circumference and found 22,000, or 1/3 gobbled down their food at a fast rate. Those who ate at a normal speed were 29 percent less likely to be obese than the gobblers and those who ate slowly were 42 percent less likely to be overweight. BMI and waist circumference were noted to be higher in the fast eating groups.
One reason for this is fast eaters may be more likely to consume more calories before they feel full. Their food choices may also be those that you can eat quickly (like a cheeseburger) rather than a salad that takes forever to get through.
Last year, researchers from Hiroshima University in Japan also found that those who ate their meals quicker were more likely to suffer from metabolic syndrome.
What is metabolic syndrome?
Metabolic syndrome is comprised of a group of risk factors that puts one at risk for heart disease, diabetes and stroke. Any three of the following classify as one having metabolic syndrome:
- Large waistline or apple shaped habitus
- High blood pressure (over 130/80)
- High fasting blood sugar (over 100)
- High triglyceride level
- Low HDL (good cholesterol)
Researchers looked at 1000 people in 2008 who didn't have metabolic syndrome and rated them as slow eaters, normal eaters and fast eaters. Those who scarfed down their food were more likely to develop metabolic syndrome within 5 years.
Previously I discussed how our eating speed has helped fuel our obesity crisis.
Fast food has become the staple of many American and European diets and we've seen obesity rise. True more people take public or private transportation to work over walking, and many have given up smoking every time they had a hunger itch, but the most popular reason for our waistline increase is fast food. But is it the caloric content of the fast food that's fueling the obesity epidemic, or the speed at which its ingested?
What is Fast Food?
According to the Merriam-Webster dictionary, Fast Food is "food that can be prepared and served quickly". A burger, shake and fries is considered fast food but so is a take away salad or sandwich. It's implied that fast food is a meal that is not made fresh but made previously and preserved such that it can taste fresh when needed to be served.
How Caloric is Fast Food?
According to CalorieKing, a McDonald's Big Mac is 540 calories. A large order of fries is 510 calories. So a meal over 1000 calories is obviously not the healthiest choice.
But let's return back to the sandwich alone. While a Big Mac is 540 calories, CalorieKing finds Chick-Fil-A's Cobb Salad (without dressing) 500 calories. Bob Evans Restaurant's Cobb Salad is 516 calories.
Now on the same site a Tuna Salad Sandwich (5 oz) w. mayo, 3 oz Bread is 679calories.
So are we becoming obese eating cobb salads and tuna salad for lunch just as one would eat a Big Mac? We don't know since people don't study cobb and tuna salad eating consumers. My guess is No.
Are we eating too fast?
Yes, and so fast that I believe it could be messing with our metabolism.
Think back to caveman days. We had to chew. And not on a soft sesame seed bun, but chew our meat. Nuts and vegetables took a chewing as well. Food was more scarce so it was savored and meals weren't on the run while on a subway or at a stop light in one's car.
Previous studies have shown that eating slowly and chewing it multiple times allow the body's signals to trigger the satiety sensation sooner, hence one would eat less.
So gulping down a burger in 5 bites could be accomplished prior to the brain receiving the signal that it should be satisfied.
Now the metabolism issue. Fast food could contain sugars, fats and preservatives that alter metabolism. But eating on the run could cause metabolism issues in and of itself.
When a body senses that the food source is short-lived, unpredictable, and coming at a speed preventing proper absorption of nutrients, it may slow down metabolism to allow the body to make the most of what it has. Eating a meal slow and methodical may be the most successful way to not only feel full but to eat less and lose weight.
I suggest a study be done looking at two groups of people eating the same food with the same caloric content but differing on the speed at which they eat it.
I suggest to you all to take an extra 15 minutes to complete your meal than what you're accustomed to and determine if you see results after a few weeks.
Of course avoiding fast food would be the most beneficial for our weight but if you must eat fast food, eat it slowly.


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Wedding Album is the third and final in a succession of three experimental albums by John Lennon and Yoko Ono. It followed Unfinished Music No. 1: Two Virgins and Unfinished Music No. 2: Life with the Lions. The album was released as by "John and Yoko", without last names mentioned. John & Yoko", the first side, a recording made on 22 and 27 April 1969, is of Lennon and Ono calling out each other's names, through a range of volume, tempos, and emotions, over the sound of their heartbeats
The Wedding Artist added 3 new photos to the album Bridesmaid Gifts. 30 March ·. No bachelorette party is complete without a sash for the bride and her team!
61: No. 9, Wedding March from Artist Unknown's Classical Serenade: Midsummer's Night Dream, Vol. 11 for free, and see the artwork, lyrics and similar artists. 61: No. 9, Wedding March. Set as current obsession. Go to artist profile. Classical Serenade: Midsummer's Night Dream, Vol. 11. Various Artists.
Wedding Night (French: Nuit de noces) is a 2001 Canadian comedy film. After winning a contest Florence and Nicolas set out to get married in Niagara Falls accompanied by their family and friends. No sooner do they arrive than the situation turns sour, and the couple decides to call the whole thing off. Stuck in an unfamiliar town with their respective relatives, Florence and Nicolas have their illusions shattered regarding love and living as a couple
Wedding Band - Making Love Out Of Nothing At All Wedding Band - The Time Of My Life Wedding Band - Hot In Herre (Full HQ Song) HD Wedding Band - I Will Survive (Full HQ Single) HD Wedding ba 1h. Artist Wedding Band №179429. play) (pause) (download) (fb) (vk) (tw). Wedding Band Making Love Out Of Nothing At All. 02:17. Wedding Band The Time Of My Life.
Wedding Song (There is Love), by Peter, Paul & Mary From the album: The Very Best of Peter, Paul & Mary, 2005 Lyrics You'll Love: Well a man shall leave his mother and a woman leave her home/They shall travel on to where the two shall be as one/As it was in the beginning, is now until the end/Woman. draws her life from man and gives it back again/And there's love. The Lord's Prayer, by Andrea Bocelli feat
So much thought goes into the wedding photo album; the venue, the ring, the dress, the wedding party, and so much more. However, there are a few scenes that you may prefer to leave out of the family album. This sexy lists of wedding pictures are great examples of a 'for his eyes only' photo series. What Will I Learn? Sexy Brides Photo With Veil. Grooms Boudoir Sexy Photos. Passionate Couple Photo Ideas. Get Inspired To Create Seductive Photos.
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Lift your heart's center to the stars in our Zodiac Bra! Then turn around to find a secret surprise. The universe granted you a sports bra with a phone pocket! You are SO welcome. Available in sizes XS-3X.
Model info:
This bra does the job to an extent... after my pregnancy my breast grew, I went from 34B to 36C and I needed to size up. It fits around but the straps are TOO LONG. It doesn't provide the support that I need to hold up my breasts. I'm a short woman and in need of more support to hold my breast up.... I wish they were adjustable!
This honestly is the only product I LOVE from this collection! It fits perfectly and it easy to get on and off! The color and shape of the top is flattering for me. I don't use the phone pocket but it's a neat idea. I'd love this style in more colors!
Originally bought a size 8 because it said it's for waist size 31 and up but it was actually too big. Had to trade in for a size 6. I recommend sizing down if you are petite with D or smaller breasts. Other than that this is perfect. I love the design, the feel and it makes me feel ready to take on any workout
I did have to order a size up as my chart size was sold out by the time I ordered however it's cute and SOOOO comfortable. The fabric is buttery smooth to the touch and this sports bra is for low intensity work outs. Im very busty and these cover me quite well. The band is a little loose but again I ordered a size up. If you're on the fence about getting these DO it! You won't be disappointed! Just order according to the chart and you'll be golden :)
I got the bra when Popflex had the combo-sale, with the leggings & the tote bag, otherwise I wouldn't have taken the chance to buy it. I have a rather small waist and large breasts, so classic sport-bras like this usually doesn't fit me, but like I said, it was a combo-sale, might as well roll the dice.
It's a beautiful bra, but just like I suspected it didn't fit. My bra size is EU 75G (I think that's 34DDD/E in US) and I bought the XL.
There's just not enough fabric to cover the girls.. If I had a few cups smaller I do think the fit would be perfect but now, sadly not.
No coverage, no support.
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Wait, is it a sporty mini dress? A workout hoodie? A casual tunic? Umm - it's all of the above! The Hypernova Hoodie Mini Dress...View full product details


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Hundreds pack out showgrounds for Toowoomba food expo
MORE than 700 people heard from 80 of the top names in fresh, chilled and frozen food at the Provincial Distributors Trade Show on Wednesday.
The major food expo, organised by the Toowoomba company at the showgrounds, was the biggest of its kind in Australia held outside of a capital city.
Stallholders included national and international brands like McCain, Mrs Mac's, Kraft Heinz, Bega, KR Castlemaine and Tip Top.
Provincial Distributors director Jackie Elliss said customers and manufacturers were already asking for the date of the next trade show.
"We haven't done one for a number of years. (The trade show) is by request from our customers," she said.
"It's an opportunity for the manufacturers to come along and present their wares.
"The food services industry is always requesting what's new in the market and they came along to see."
Mrs Elliss said the windfall from the show would not just be felt by the food industry, with many Toowoomba hotels and accommodation providers filling up with exhibitors.
"They just about booked up the motel at the City Golf Club," she said.
"Many rooms were taken up in motels, and that should help the local businesses.
"The amount of people We brought people into Toowoomba who stayed here for a couple of nights."
The Toowoomba Chamber of Commerce partnered with the expo, showing off local food suppliers to national brands.
CEO Jo Sheppard said the trade show offered a chance for networking between suppliers and the food industry.
"It was great for our local food producers to discuss supply chain opportunities with big names and also to talk with local cafes and restaurants that came along," she said.
"Many of the manufacturers flew directly into Wellcamp from Melbourne, so it's a good example of what's now possible, now we have that connectivity through Wellcamp."


text:
goodS & ServiCeS
continued from pg 17
choic es
Best place to buy cDs or vinyl recorDs Discology 11 N. Sierra St., 323-2121
It's unlikely anyone bet on David Calkins' success when he opened a CD store on the second floor of a building on California Avenue. Locally owned and chain CD stores had folded in Reno. Discology not only survived but moved downstairs and downtown, next to the Century Riverside movie theaters. Calkins has thrived, even expanding into movies and vinyl. He's a tribute to personal enterprise.
Best gym
Best liquor store
St. Mary'S Center For HealtH & FitneSS
total wine & More
645 N. Arlington Ave., 770-3800
Best hardware store Carter BroS aCe Hardware 1215 S. Virginia St., 337-1200
Best head shop art dogS & graCe 218 Vassar St., 324-2787
Saint Mary'S regional MediCal Center
outletS at legendS 1310 Scheels Drive, 358-3800
Best house cleaning service
Best medical marijuana dispensary
Molly Maid
Mynt CannaBiS diSpenSary
1380 Greg St., 359-1503
132 E. Second St., 686-6968
Best jewelry store
Best mortgage company
3705 Barron Way, 857-4333
Best local place to work
1201 Steamboat Pkwy., 337-4600
Signature landSCapeS
675 Holcomb Ave., 384-1456
rC willey HoMe FurniSHingS
Best landscaping company
tHe glaSS die
235 W. Sixth St., 770-3194
1401 S. Virginia St., 786-5110
Best local Business
Best home furnishings store
MiCHael and SonS Jewelry Co.
6671 S. Virginia St., 853-3669
Best mall
greater nevada Mortgage 6745 Sierra Center Pkwy., 888-6999
Best motorcycle dealer Battle Born Harley-davidSon 2900 Research Way, Carson City, 882-7433
Best of Northern Nevada 2018


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North Chickamauga Creek Conservancy
North Chickamauga Creek begins with the union of two small streams, Standifer and Brimer Creeks, near the western rim of Walden's Ridge in Sequatchie County, approximately 15 miles from the city of Chattanooga. As the creek flows eastward into Hamilton County, it collects flow from Mossy, Cain, and Cooper Creeks and their upland tributaries before beginning a rapid descent toward the valley floor.
North Chickamauga Creek cuts a spectacularly scenic, deep central gorge through the sandstone of the Cumberland Plateau. Past Hogskin Branch, the creek curves southward, rounding the wall of the escarpment. As it enters the valley, the waters of the creek spill into several caves and fissures eroded into the porous limestone of the valley floor, causing the stream to disappear during much of the year to leave an exposed bed of dry white cobbles. A short distance downstream, the creek reemerges to wind its way through the Soddy Daisy, Middle Valley, and Hixson communities before emptying into the Tennessee River just below Chickamauga Dam. In its 32-mile course from ridge top to river, the creek drains some 120 square miles of upland and valley land.
The first segment of the North Chickamauga Creek Greenway was dedicated on May 19, 1990. This 1.25 mile section on 40 acres of TVA's Chickamauga Dam Reservation includes a paved multi-use trail, a picnic pavilion, restroom facilities, and an improved canoe access point. TVA designated the remaining 200 acres of the parcel as a Small Wild Area; the area has also been designated as an Urban Wildlife Sanctuary by the National Institute for Urban Wildlife and as a State Natural Area by the Tennessee Department of Environment and Conservation. At the time of the dedication, TVA donated an easement to manage and maintain the 40-acre greenway tract to the City of Chattanooga.
Days after the dedication of the TVA Small Wild Area, the Chattanooga City Council authorized the purchase of what is now known as the Greenway Farm, a 180-acre farm that adjoins the northern boundary of the initial greenway segment with 2.5 miles of creek frontage. The greenway trail now extends through this park and features additional canoe access points. NCCC in conjunction with the City of Chattanooga, the Trust for Public Land, and other project partners released an updated greenway plan in 2004. The Chattanooga City Council voted to partially fund the next section of greenway trail construction in July 2009. NCCC continues to assist the City of Chattanooga in the land acquisition process for further development of the greenway and protection of the creek.


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Many of you will know that as part of our conservation management work on our heathland sites we run a small herd of Belted Galloway Cattle. The time of year has come for some of our steers to go to the abbatoir, therefore we are now able to offer for sale to the public some of the finest beef you are likely to be able to buy (of course I am biased, and proud of it!).
These rare breed cattle have spent their life grazing outdoors on conservation managed heathlands and wild flower rich grasslands around Haslemere. We like to think they have about the best life it is possible for cattle to lead. They help us to manage the habitats, and through the action of their grazing encourage the conditions in which numerous rare and fascinating species of wildlife flourish. We have started a system whereby we are breed our own replacement animals and later on in the winter our cows will be heading off to holiday with a Belted Galloway bull. Selling beef in this way provides the funds to enable us to purchase breeding animals so that we can keep a dynamic and healthy herd.
The beef will have been traditionally butchered and hung for three weeks to provide the kind of flavour your average supermarket steak will simply never be able to match. It will be ready to collect in early December, just in time for Christmas.
Collection will be in person on 8th or 9th December from Swan Barn Farm in Haslemere, giving you the opportunity to call in and have a look at the Speckled Wood Building while you are here. We are selling 5kg boxes for £50 and 10kg Boxes for £95. Each box will contain a mix of high quality cuts of beef including everything from roasting joints to steaks and mince. To place an order call 01273 857712 or email firstname.lastname@example.com
We anticipate demand to be high so I would suggest getting your order in early to avoid dissapointment. I really hope people like it, we are very proud of our little herd and what they accomplish for us, I think this is a really positive way of supporting the management of the countryside around the town and have already put my name down on the list.


text: Section: Cars Title: 1990 Coupe quattro Price: 399.00 Location: ri Date: December 07, 2008 Contact: Paul Email: buycash at yahoo.com Phone: Description: NO PICTURES. Shell more or less...complete interior. Missing fenders,bumper,window regulators,cluster. Still Complete drivetrain with 160k...bent valves. Clean title..good for a race/rally project URL: http://www.audifans.com/marketplace/show.php?table=pm_audifans_Cars&id=4649 -- [ This is an automated message ] [ You are receiving this message ] [ because you signed up for the ] [ Marketplace email notification. ]


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Original Soundtrack - Amy [Original Soundtrack] album mp3
- Performer:Original Soundtrack
- Title:Amy [Original Soundtrack]
- Genre:
- Size FLAC version1288 megabytes
- Size MP3 version1114 megabytes
- Size WMA version1959 megabytes
- Rating:4.6
- Votes:132
- Formats:AAC DXD VOC WAV WMA RA
Amy is an original motion picture soundtrack to the 2015 film of the same name. It was released by Island Records on 30 October 2015. It is also the second posthumous compilation album by English singer and songwriter Amy Winehouse (the subject of the film). It features unreleased songs and demos that were included in the documentary and also features music by Brazilian composer Antônio Pinto. The soundtrack peaked at number 19 on the UK Albums Chart.
Antonio Pinto, Amy Winehouse. Mark Ronson, Amy Winehouse. Antonio Pinto, Amy Winehouse.
AMY (Original Soundtrack) Tracklist. 1. Opening by Antônio Pinto Lyrics. Back To Black Lyrics. 14. Cynthia by Antônio Pinto Lyrics. Body and Soul by Tony Bennett (Ft. Amy Winehouse) Lyrics. 22. Amy Forever by Antônio Pinto Lyrics.
But in the AMY: The Original Soundtrack, Amy Winehouse is actually outnumbered: her 11 B-sides are broken up evenly by 11 snippets of film score, with the balance tipped by one exceedingly unnecessary trip-hop track, originally released in 1995. This is not for lack of material. Winehouse began her public singing career at age 16 with the National Youth Jazz Orchestra, performing and recording regularly for the next decade until her death. The rest of the soundtrack is a mix of album cuts and live recordings, compiled primarily as signposts for the documentary's plot. There is no raw audio on the soundtrack whatsoever; it's much glossier than the film itself, which heavily relies on rough footage and successfully illuminates Winehouse outside her press narrative as a result.
Back to Black (Acapella, Album Medley) (03:50) 14. Cynthia (01:16) 15. Rehab (Live on Jools Holland) (03:42) 16. In the Studio (01:06) 17. We're Still Friends (Live At The Union Chapel) (02:57) 18. Amy Lives (02:16) 19. Love Is a Losing Game (Live At Mercury Music Awards) (02:33) 20. Arrested (01:05) 21. Body and Soul (03:24) 22. Amy Forever (02:50) 23. Valerie (BBC Radio 1 Live Lounge) (03:53). Лейбл Island Records издал саундтрек фильма AMY: альбом вышел 30 октября . You can download the torrent file on the top of the page. Look for more music Amy Winehouse, Antonio Pinto.
A soundtrack album is any album that incorporates music directly recorded from the soundtrack of a particular feature film or television show. The first such album to be commercially released was Walt Disney's Snow White and the Seven Dwarfs, the soundtrack to the film of the same name, in 1938. The first soundtrack album of a film's orchestral score was that for Alexander Korda's 1942 film Jungle Book, composed by Miklós Rózsa.
Features Song Lyrics for Amy Winehouse's AMY (Original Motion Picture Soundtrack) album. Amy Winehouse - AMY (Original Motion Picture Soundtrack) Album. Artist: Amy Winehouse. Send "Amy Winehouse" Ringtones to your Cell. Album: AMY (Original Motion Picture Soundtrack).


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Port Authority
Panorama | Contemporary World Cinema
Danielle Lessovitz's romance features Fionn Whitehead (Dunkirk) as Paul, a macho but vulnerable young man drawn into New York City's drag scene by his attraction to the beautiful Wye (Leyna Bloom). Arriving in the city from Pittsburgh via the bus terminal that gives the movie its name, Paul is struck by the sight of Wye and her friends voguing it up on the steps outside. When the two later meet at a drag ball rehearsal, the attraction is cemented - though it will be tested when Paul learns that the object of his affections is trans…
Vividly shot and pleasingly authentic, Port Authority is the type of NYC-set movie one savours for the sociological detail; Lessovitz portrays the "Kiki" subculture of drag performance with verve and creativity, and also opens a window onto the world of homeless young adults in the city. First-time actress Bloom, herself a trans woman, has a proud, feline beauty to her, and Whitehead exudes a tender naïveté in his role.
"A heartfelt and sensual trans love story… made with storytelling gusto." - Peter Bradshaw, Guardian


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Crown BoxesFurnished content.(from Lumberjocks.com)Here are some crown boxes I made at a John Wilson workshop. They are cherry bands with a maple rim. The rim is held on with brass pins. The name crown boxes came from Scott Phillips when he and John were having lunch at least that story. Read more here
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Band saw boxeFurnished content.(from Lumberjocks.com)Just completed what I call the twins, walnut and maple, finished with water based poly. The flocking really does reduce the sanding time as it hides saw cuts. Read more here
Ridgid R4512 Folding Outfeed TableFurnished content.(from Lumberjocks.com)Here is yet another folding outfeed table. I got a lot of good ideas on how to make this from other LumberJocks, so thanks! I can't believe I waited 3 years to add this to my table saw. This should have been my second project, right after a couple push sticks and feather boards.Pretty simple materials, mostly scraps or leftovers from other projects. Add in some bolts and a couple of door hinges and voila! Read more here