text:
Parallels Virtuozzo Containers is an operating system virtualization solution that maximizes your investment in server hardware. Parallels Virtuozzo Containers is uniquely suited to Cloud server virtualization, enabling near instant provisioning and on-the-fly modification of hosting and Cloud server plans while delivering maximum density, cost efficiency and application performance.
Leading service providers Go Daddy, 1&1, Host Europe and Media Temple rely on Parallels Virtuozzo Containers to deliver a full range of hosting and Cloud services
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Parallels Virtuozzo Containers delivers three times more virtual servers than hypervisor solutions providing greater utilization of existing infrastructure.
Centralized management enables fast operating system (OS) updates and upgrades. Make changes once and quickly replicate to an entire datacenter.
Parallels Virtuozzo Containers enables near-native server performance, delivering maximum application performance and scalability for a given virtual CPU configuration.
Rapid provisioning means new Servers can be available within minutes of ordering, and servers are "instant on" when provisioned with no OS boot up time. Customer self-service panels enable existing OS containers to be scaled on the fly with real-time adjustments to CPU, memory and disk space allocations.
With Parallels Virtuozzo Containers service providers can deploy a super-efficient Cloud hosting infrastructure and offer a wide range of hosting and Cloud services that appeal to the broadest possible customer base. Parallels Virtuozzo Containers is optimized to work with all Parallels hosting and Cloud enablement solutions including Parallels Plesk Panel, Parallels Automation and Parallels Business Automation Standard. Learn More
Virtualization at the host operating system provides a lean, efficient virtualization layer that enables higher density ratios of virtual servers to physical servers. With Parallels Virtuozzo Containers you can increase the utilization of existing servers by 3x over hypervisor solutions, delivering cost savings not only in maintenance and energy costs but also by reducing new server expenditures.
Parallels Virtuozzo Containers for Linux combines advanced management and high density virtualization to create a flexible and powerful solution for today's demanding Cloud service offerings.
Parallels Virtuozzo Containers for Linux sets the hosting industry standard for profitable, secure and flexible VPS and Cloud server offerings. With Parallels Virtuozzo Containers for Linux you will be able to:
Parallels Virtuozzo Containers for Linux is simply the best server virtualization solution for VPS and Cloud server offerings. New OS containers can be provisioned in seconds. Existing OS containers can be scaled on the fly. Administrators can make changes once and quickly replicate to an entire datacenter. Applications execute at full speed with direct access to the native hardware. Running OS containers can be migrated "live" between different hosts without the need for specialized storage hardware.
Parallels has been a strong participant within the Linux community for more than a decade and was recently recognized by the Linux Foundation as one of the top ten commercial contributors to the kernel. As a participating member of the Linux foundation Parallels is heavily involved in workgroups and events alongside other Linux community leaders. This experience, access to innovators and involvement with the Linux community helps Parallels to continually advance Parallels Virtuozzo Containers and deliver the best solutions for our customers.
Change the cost equation of delivering Windows Cloud Servers and VPSs by maximizing hardware utilization and simplifying day-to-day management.
Hosted Desktop-as-a-Service (DaaS) applications use virtualization technology to create user desktops and can potentially pair with many other technologies as a part of a complete solution. The benefits to the DaaS approach are many, including simplifying patch management and provisioning new applications to users in seconds. Parallels Virtuozzo Containers for Windows provides significant benefits for hosted DaaS deployments including a much smaller footprint (resulting in a higher density of desktops), the ability to quickly customize desktops including permissions levels, and unbelievably fast provisioning and update management. Learn more
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katie. 23. leo.
chi-town love.
ghostly white skin; bubblegum lips; puppy dog eyes; lion's mane.
officer with the grammar police.
elton john & freddie mercury obsessed.
white sox fan.
blackhawks fanatic.
criminal psychology student.
neverland dreamer.
whiskey drinker.
lion lover.
social butterfly.
latte ADDICT.
ED survivor.
simply the best.
Catching Elephant is a theme by Andy Taylor
(via imgTumble)

subset: commoncrawl


text:
21 Hours of TWISmageddon
13 December 2012 2:19 PM | 3 Comments -
Need recording of TWIS from 8/16/2012
21 August 2012 4:20 PM | 1 Comment -
TWIS adopts Google+ Hangouts and YouTube Live!
26 July 2012 11:12 AM | 4 Comments -
Regarding the rumors of Cancellation
19 June 2012 12:00 AM | 82 Comments -
2010 TWIS Science Music Compilation Is Available!
25 January 2012 3:08 PM | 5 Comments
21 Hours of TWISmageddon
TWIS 2010 Science Music CD
Donate to TWIS
Support TWIS
Make A DonationNew T-Shirts!
World Robot DominationTWIS Discussions
- John Moehrke on About
- Kerry on 28 February, 2013 – This Week in Science
- Ross Anderson on About
- Jonny on About
space Archive
02 May, 2013 – This Week in Science
SpaceShipTwo Goes Airborne, Little Movies, Saturnian Hurricanes, Chinese Flu News, Torpor Or Hibernation?, Cannibalistic Maggots, Birds For Boys, Men Vs Women, Island Chihuahuas?, Tunguska Meteorite Samples, HPV For Cancer, Think You're Old?, And Much More... -
25 April, 2013 – This Week in Science
The Mars Draft, Bird Flu News, Hobbitses, Vervet Mimics, Yay God, Near Death Hibernation, No Memory, Being A Genius, Radioactive Bacteria, Origin Of Limbs, And Much More... -
18 April, 2013 – This Week in Science
Life Gets Older, Better Cancer Radiation, Dog Lives, Dog Beds, Electronic Gene Zippers, Flying Insect Robots, Carnivorous Madagascar Dino, Super-Habitable Earth, And Much More... -
28 March, 2013 – This Week in Science
Speed O'Light, My Brain Hurts, Human Cave Man, Healthier Fruit Flies, Fish For Fuel, NASA Sequester!, Men vs. Women, Bacterial Diet Plan, Bacterial Fun Ride, Snakebot, Jellybot, Jurassic Science?, And Much More... -
21 March, 2013 – This Week in Science
Olive Oil Health, Algal Thieves, Dangerous Young Men, Cock-A-Doodle-Do!, King Of The Brain, Sports Science, Old Man Universe, Water Voles, And Much More... -
14 March, 2013 – This Week in Science
Mars Alive, Corona Danger, Bear Lineage, No More Animals!, Economical Cockatoos, Monkey Brains, South Pole View, Higgs Party!, HR8799c, Hole In The Ocean, Olive Oil Goodness, No Cancer E, 4-Winged Dino, And Much More... -
07 March, 2013 – This Week in Science
Return Of The Hobbit, Citizen Science, Vostok Is Alive!, Gateway To The Nucleus, Anti-bacterial Wings, Picky Moms, TWITEOTW, Caffeine Boosting Bees, Pinky And The Brain, Wireless Brain Implants, TWIWRD, And Much More... -
28 February, 2013 – This Week in Science
Is ENCODE All That?, Spinning Supermassive Black Hole!, Bacula Get Smaller, Colonic Antibiotics?, Rat Mind-Meld, Chemotherapy - Better Than Ever, Retire On Mars, And Much More...


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MLB Betting
Play along with the boys of summer with Sports Interaction! It�s the home for the best in MLB baseball betting action � from Spring Training to the World Series, you�ll be dialed into all the action from the diamond by playing with Sports Interaction�s industry-leading online sportsbook. After a hectic off-season, it�s time for some questions to be answered. Can the Philadelphia Phillies rise again after adding the arm of Cliff Lee? Will new arrivals Carl Crawford and Adrian Gonzalez bring the Boston Red Sox back to the World Series? Can the San Francisco Giants make it back-to-back titles? Or will the New York Yankees reign once more? If you think you know the answers to any of these questions, turn your knowledge into cash by playing at Sports Interaction�s online sportsbook. Don�t delay � get in on MLB baseball betting today!
MLB Betting Rules
General betting rules apply to all MLB betting. In addition, the following rules are specific to betting on MLB Baseball.
- The outcome of 5 Inning betting and 5 Inning over/under betting is determined by the team scores after the first 5 full innings of the game (i.e. after the home team's fifth inning). Should a game be abandoned in the bottom of the fifth inning and the home team is ahead, the final official result will be used to determine the outcome.
- Half-time/Full time is the outcome after 5 full inning of play and the end of the game.
- When betting on total runs (over/under), the run line (+1.5/-1.5), Winning Margin, Half-time/Full-time, most runs scored, or highest scoring innings the game must go 9 innings for 'action' (8 � if the home team is ahead). If a game is called or suspended after that time, the score will be determined after the last full inning of play.
- When betting on the moneyline, team to score first wins, last team to score, odd/even game total or odd/even team totals the game must go to the losing team's 5th inning at least for 'action' to count (or 4 � innings should a game be called in the bottom of the 5th and the home team is ahead).
- Extra innings, if played, will count in the final result for all bets except 9 highest scoring inning.
- Betting on total runs (over/under), the runline (+1.5/-1.5), 5 Innings, Winning Margin, Half-time/Full-time, race to 3 runs, first run scored, most runs scored, highest scoring innings, 1st home run of the game, team to score first wins, first team to score, last team to score, odd/even game total or odd/even team totals is offered on the basis of both listed pitchers starting the game. Both pitchers must start the game and throw at least one pitch for bets to have 'action.' If either listed pitcher fails to start the game for any reason, the bet will be deemed to have 'no action' and the stake will be returned.
- Game must go at least 5 full innings for 5 Innings bets to have action. Should a game be called in the bottom of the 5th inning and the home team is ahead, all bets have action.
- All bets except for certain moneyline bets will be void in the event of a pitching change. You can place a new bet once the new starting pitcher has been determined.
- When betting on the moneyline, there are two options available:
- You may choose 'action' - the bet has action regardless of which pitcher starts.
- You may choose 'no action' - both listed pitchers must start for the bet to have action.
- In the event of a pitching change prior to the game, moneyline bets chosen as 'action' will stand, but the price of the bet may be adjusted to the opening price with the new pitchers. Bets chosen as 'no action' will be void in the event either pitcher listed at the time of the bet does not start.
- All games must start on the scheduled date for bets to have 'action'. If a game has been postponed or cancelled before its due start time, all bets are deemed 'no action'.
- Winning Margin: Winning margin betting is from scratch.
- When betting on the moneyline, the game must go to the losing team's 5th inning at least for 'action' to count. If a game is cancelled or suspended after that time, the winner is determined after the last full inning of play.
- For betting purposes suspended games do not carry over to the following day. All bets settled according to the score on the scheduled day of game, regardless of any play on subsequent day(s).
- Series betting � Bets on series are based on the first three games played of each series. Neither team can play another opponent between scheduled games. If one of the first three games is postponed, all bets stand. If less than three games are played, the team leading the series will be considered the winner of the series. All games must go to the losing team's 5th inning to count toward the series. No listed pitchers. All bets stand regardless of who starts each game. Note: Bets on post-season series are based on the team to win the series, regardless of the number of games involved.
- Grand Salami and 'Home vs Aways total runs scored' bets � All games must go 8.5 innings for action. No listed pitchers. All bets stand regardless of who starts each game.
- Game with highest runs total, team to score the most runs, lowest team score of the night, and largest margin of victory - No listed pitchers. All bets stand regardless of who starts each game however selections involving games or teams that don't go at least 8.5 innings have no action. Winning bets on all remaining selections will have their odds reduced in accordance with Tattersall's rule 4.
- Game must go at least one full inning for first inning over/under, to have 'action.'
- If there is a result in first team to score, 1st home run of the game, first run scored, will there be a run in the first inning, all bets have action regardless of how much of the game is played.
- When betting on race to 3 runs, the game must go 9 innings for action (8 � if the home team is ahead) unless one team has scored at least 3 runs. In the event that one team scores at least 3 runs, all bets have action regardless of how much of the game is played.
MLB Betting Guide
Baseball is the great summer sport of the United States, and the 162 game regular season of Major League Baseball, running from April to September, offers many betting opportunities to the bettor. The most important person in a baseball game is the pitcher, which is why no baseball betting line is posted without naming the starting pitcher. Both starting pitchers much make at least one pitch for the game to be considered �action.� If there is a change of one or other of the starting pitchers, all runline and total bets are voided and the stakes returned, while an odds adjustment takes place on the moneyline prices.
NY Yankees: CC Sabathia | +1.5 | -190 |
Boston: J Beckett | -1.5 | +160 |
In the example above, the New York Yankees, with CC Sabathia as their pitcher, is the underdog, as indicated by the plus (+) sign in the runline. These figures mean that anyone betting on the New York Yankees wins if the New York Yankees either win or don�t lose to Boston by more than 1.5 runs. The second number, -190, is the price � this means that the if the New York Yankees win or don�t lose by more than 1.5 runs the bettor wins $100 for every $190 wagered.
In the second line Boston, with Josh Beckett as its pitcher, must win by more than 1.5 runs for the bet to win. In this event, the bettor wins $160 for every $100 wagered.
Baseball betting offers markets in the moneyline, runline (the same principle as pointspread betting) and totals. The game must go to the losing team�s 5th inning at least for the moneyline to be considered �action.� In runline or totals betting, the game must go to nine innings (or 8.5 if the home team is ahead) to be considered �action.� Extra innings will count in the final result for all bets.
MLB Betting News
Blue Jays out to extend streak vs. Canadian Jeff Francis
The Toronto Blue Jays have won six straight games and are playing their best baseball of the season despite a rash of significant injuries. After going just 10-17 in April with a healthy pitching staff, the Jays have won eight of 10 this month with two starters on the shelf. When you dig a deep [...]
Jays manager John Gibbons has hands full with Brett Lawrie
In many ways, Toronto Blue Jays third baseman Brett Lawrie is the kind of player every baseball manager wants to have in his lineup. Lawrie's young and exciting. He's a five-tool guy that plays the game hard. His potential is through the roof, but the problem is, his antics are might just make John Gibbons [...]
Montreal names street after Hall of Famer, Expos star Gary Carter
The late Gary Carter last wore a Montreal Expos jersey back in 1992, but the impact he made on Montreal baseball fans lives on. The city will honor the Hall of Fame catcher Tuesday by naming a city street after him. Carter died in February after a battle with brain cancer. He played for the [...]
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This article was originally distributed via PRWeb. PRWeb, WorldNow and this Site make no warranties or representations in connection therewith.
SOURCE: MyHotElectronics
My Hot Electronics currently has the Playstation Vita console available for $209.99, while supplies last. The console is a handheld console that plays various games, media and music content.
Detroit, Michigan (PRWEB) October 07, 2012
MyHotElectronics.com announces that the store has marked down the Playstation Vita to $209.99, while supplies last. The console is the wi-fi version.
The console can play various content, including PS One games, music, video and other PSP games downloaded from the Playstation Store. The system comes equipped with 2 digital cameras (front and rear), 5-inch touch screen, as well as dual analog sticks.
The store also has the Madden NFL 13 Playstation Vita Bundle available for $220.00, down from the retail price of $249.99. The bundle comes with the Vita console, as well as the recently released Madden NFL 13 video game. The store is also taking preorders on upcoming Vita bundles for Call of Duty: Black Ops Declassified and Assassin's Creed III.
In terms of accessories, MyHotElectronics.com has deals on the Vita memory cards, with markdowns up to 38% off. The cards are available in 4GB, 8GB, 16GB and 32GB sizes.
For more information, visit MyHotElectronics.com.
About My Hot Electronics -
My Hot Electronics is a leading online e-commerce provider of electronics which range from tablets, PCs and cameras to video games, DVDs, Blu-Ray Discs, appliances, lawn and garden products and more.
The store also carries the top brands in electronics and apparel including, Nike, Adidas, Apple, Sony, Samsung, Microsoft, EA Sports, and many more. The company recently began its initial expansion into clothing and jewelry and will continue to expand over the next several months.
The store recently launched an online grocery store service to further the growth of its brand. The service will allow for food items to be delivered in bulk, such as meats, breads, breakfast items, and more.
Recently, My Hot Electronics' affiliate store, SportsFanPlayground.com, announced deals on various NBA jerseys for the upcoming season. Fans will be able to order top jerseys from players such as LeBron James, Kobe Bryant, Dwight Howard and more. The store has apparel and accessories from the NBA, NFL, NHL, MLB, UFC, WWE, FIFA and many more. The site also features collector's items, autographed pieces and various sporting goods.
For the original version on PRWeb visit: http://www.prweb.com/releases/prwebplaystationvitasale/myhotelectronics/prweb9987596.htm


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Safari Books Online is a digital library providing on-demand subscription access to thousands of learning resources.
1-2 of 2 Items < Prev | 1 | Next >
1. | By: Richard Froom - CCIE No. 5102; Balaji Sivasubramanian; Erum Frahim - CCIE No. 7549 Publisher: Cisco Press Publication Date: 21-JUN-2010 Insert Date: 05-JUL-2010 Slots: 1.0 | Implementing Cisco IP Switched Networks
(SWITCH) Foundation Learning Guide: Foundation learning for SWITCH
Richard Froom, CCIE No. 5102
Balaji Sivasubramanian
Erum Frahim, CCIE No. 7549
Implementing Cisco IP Switched Networks
(SWITCH) Foundation Learning Guide is a Cisco®
authorized learning tool for CCNP® and
CCDP® preparation. As part of the Cisco Press
foundation learning series, this book covers how to plan,
configure, and verify the implementation of complex enterprise
switching solutions using the Cisco Campus Enterprise Architecture.
The Foundation Learning Guide also...
2. | Cisco LAN Switching Configuration Handbook, Second Edition By: Steve McQuerry - CCIE No. 6108; David Jansen - CCIE No. 5952; David Hucaby - CCIE No. 4594 Publisher: Cisco Press Publication Date: 19-JUN-2009 Insert Date: 07-JUN-2009 Slots: 1.0 | Overview: Cisco LAN Switching Configuration Handbook, Second Edition Cisco LAN Switching Configuration
Second Edition
A concise reference for implementing the
most frequently used features of the Cisco Catalyst family of
Steve McQuerry, CCIE® No. 6108
David Jansen, CCIE No. 5952
David Hucaby, CCIE No. 4594
Cisco LAN Switching Configuration
Handbook, Second Edition, is a quick and portable reference
guide to the most commonly used features that can be configured on
Cisco® Catalyst® switches. Written to be used across all
Catalyst IOS platforms, the book covers general use of Cisco
IOS®, followed by a series of chapters that provide...
1-2 of 2 Items < Prev | 1 | Next >


text:
1. | Woosh | ||
Used to denote when a comment has gone over someone's head. Onomatopoetic to the sound of an object moving past you at an accelerated pace.
Made even funnier when saying "woosh" also makes no sense to the person that earned the "woosh", thus making a combo that cannot be countered until combo-broken. Sometimes typed as /woosh in an MMORPG setting, as if something making no sense to someone was an emote of some kind. tofu: "I'd love to see a snuff film star named Gorey Feldman."
dahll: "What are you talking about?" tofu: "Woosh" dahll: "Woosh?" grad-o: "2-hit combo!" |
Woosh images | |||
2. | woosh | ||
This, along with the joke, had gone over your head. You: It's not funny that's a serious issue!
Joker: WOOSH! You: *Looks up woosh on Urban Dictionary* |
3. | Woosh | ||
A way of passing energy and showing spirit, oftentimes in a way that makes newcomers feel uncomfortable. An icebreaker that Jeff brought to the Whitney team on the first day of summer training in 2011. When someone introduces themselves, you must say their name back to them followed by the woosh. There is really no explanation for it, other than the fact that it's awesome and severely under appreciated by those not on the Whitney team. Speaker: "Hi I'm Jeff."
Response: "Hi Jeff!" *clap* *clap* "WOOSH". You have now been wooshed. |
4. | Woosh | ||
To confirm a friends burn or comeback in an argument or battle. As to back him up. WOOSH!
5. | woosh | ||
1.(n) The sound something makes when passing by at moderate speed.
2.(v) To pass by an object at such a speed as to make a "wooshing" sound. 3.(n) The handle of some British idiot with a penchant for various acts of dumbassery and creating some of the most homoerotic sprite comics ever to grace the interweb. 1. The car zipped by with a woosh.
2. The car wooshed by. 3. I ran down woosh with my car. |
6. | woosh | ||
Extremly Fast; anything holding relationship to being fast. Originating from the film "Prefontaine", the term is most often used to reference the speed and ability of a competitive distance runner. Used as a compliment.
"Yeah, I won the cross-country meet. That's how woosh I am."
7. | woosh | ||
Derived from the "wooshers" several years ago in W. Orange, NJ.
"Wooshers" are those who 'wish' or in the v-language, "woosh". What they wish for is just about anything, from getting leud to winning the lotto, they just woosh. The Wooshers wooshed they had a man. They Jewannaman.


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Κάντε κράτηση online ή τηλεφωνήστε:
00800 4414 1518 ΔΩΡΕΑΝ από σταθερό τηλέφωνο24 ώρες την ημέρα, 7 ημέρες την εβδομάδα (οι κλήσεις απαντώνται στα αγγλικά)
Μπορεί να υπάρχουν χρεώσεις για επιπλέον άτομα, οι οποίες εξαρτώνται από την πολιτική του ξενοδοχείου.
Κατά το check-in απαιτείται να προσκομίσετε μία ταυτότητα κι εγγύηση σε μετρητά ή πιστωτική κάρτα για τυχόν επιπλέον χρεώσεις.
Τα ειδικά αιτήματα εξαρτώνται από τη διαθεσιμότητα κατά το check-in και μπορεί να απαιτούν επιπλέον χρεώσεις. Τα ειδικά αιτήματα δεν είναι εγγυημένα.
Αυτό το ξενοδοχείο δε διαθέτει παροχές προσβασιμότητας για άτομα με αναπηρία. Επιλέξτε ένα άλλο ξενοδοχείο, εάν θέλετε το δωμάτιο να διαθέτει τέτοιες παροχές.
Προσφέρεται δωρεάν πρωινό (σε μπουφέ) στους επισκέπτες.
Το Old Stone Inn Mountain Lodge & Restaurant διαθέτει εστιατόριο στο χώρο των εγκαταστάσεων.
Guests arriving after 8 PM Monday - Saturday or after 5 PM on Sunday can find check-in instructions in the box labeled "Late Arrivals" beside the office door.
Guests can contact the property using the number on the reservation confirmation received after booking.
Μπορεί να υπάρχουν χρεώσεις για επιπλέον άτομα, οι οποίες εξαρτώνται από την πολιτική του ξενοδοχείου.
Κατά το check-in απαιτείται να προσκομίσετε μία ταυτότητα κι εγγύηση σε μετρητά ή πιστωτική κάρτα για τυχόν επιπλέον χρεώσεις.
Τα ειδικά αιτήματα εξαρτώνται από τη διαθεσιμότητα κατά το check-in και μπορεί να απαιτούν επιπλέον χρεώσεις. Τα ειδικά αιτήματα δεν είναι εγγυημένα.
Ο / η επισκέπτης δεν άφησε σχόλιο.Αληθινό σχόλιο πελάτη της Hotels.com
"Hot water is sort of important"
We stayed at Old Stone Inn for one night in the process of moving my son out of college. It was really just a layover, but the pervasive smell of mildew in our room and complete lack of cold water in the morning made for a less than satisfying experience. Do not recommend.Αληθινό σχόλιο πελάτη της Hotels.com
Ο / η επισκέπτης δεν άφησε σχόλιο.Αληθινό σχόλιο πελάτη της Hotels.com
"yes it is a great place"
Very goodΑληθινό σχόλιο πελάτη της Hotels.com
"Cozy, lodge feel"
Rooms were very cozy. Bathrooms were a little small and we had a tiny television in our room. I didn't mind this but my 11year old son did. Very friendly and helpful staff. I would definitely stay here again!!Αληθινό σχόλιο πελάτη της Hotels.com
"Very convenient"
The place was very convenient to downtown and restaurants and the staff was as friendly and accommodating as could be. Everything was comfortable, but even with the fireplace lit and the room warm, with outside temperatures in the low 30s the floor was quite cold and also the bathroom was cold.Αληθινό σχόλιο πελάτη της Hotels.com
Ο / η επισκέπτης δεν άφησε σχόλιο.Αληθινό σχόλιο πελάτη της Hotels.com
"Rustic and loaded with charm - Perfect weekender!"
I can't say enough great things about this awesome discovery that we made by finding this hotel on Expedia! My husband and I needed to get away for a short weekend to celebrate our anniversary and spend some much-needed time without the kids. The Old Stone Inn is a wonderful mix of a bed & breakfast style hotel and an old lodge. It was a great value […] for the weekend and who knew Waynesville had so much to offer? I had never even heard of the town before this weekend. Cute shops and great restaurants all in the Smokey Mountains. We just loved it! The lodge is definitely rustic, but so incredibly charming. The words quaint and cozy describe it perfectly. The owners really should put new pictures up as I think the current ones don't do the lodge justice. We brought our own coffee maker, plenty of our own ice, and a box fan to drown out any possible noise from other rooms. The fan turned out to be a good idea because the heaters in the rooms are the old-fashioned style that will wake you up when they turn on and off throughout the night. We love vacations with our kids dearly, but it was refreshing to take a weekend for just us in a town that seems to be made for couples. We laughed at the fact that we saw more dogs than kids in the town square shopping area of Waynesville! Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Expedia
"Very good for the money"
TV and bathroom was small but not a big deal. Breakfast included in on the price of room and it was delicous!!Αληθινό σχόλιο πελάτη της Hotels.com
"Nice setting."
We really enjoyed the Rustic atmosphere of the Inn. However our gas logs did not work and if you leave in the evening and come back late it's hard to find a parking space as the dinning room is open to the public. The breakfast was great.Αληθινό σχόλιο πελάτη της Expedia
"Old fashioned hospitality"
Very enjoyable. Make dinner reservations early.Αληθινό σχόλιο πελάτη της Hotels.com
"Great room and breakfast"
Great breakfast, small bathroom. The room is beautiful and comfortable. But the signal of WIFI is too weak.Αληθινό σχόλιο πελάτη της Expedia
"Great place"
Great location, friendly staff. Certainly a good choice to stay.Αληθινό σχόλιο πελάτη της Expedia
"Secret Hideaway"
Rooms come with an excellent breakfast. Rustic rooms are clean and comfortable. Main Lodge is beautiful original with exposed beams and fireplaces. The staff is very pleasant and helpful.Αληθινό σχόλιο πελάτη της Hotels.com
"Quiet get-away."
Staff was truly superb and seemed to care about all of us. We were in a large family group, so they had to "tend" to us more at once, but they handled it well and were so very pleasant. The lodge was more rustic than expected, but no phone or computer were kind of nice for relaxing with the family. Food was excellent and everyone worked very hard to […] make the experience a nice one. We would return. Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Expedia
"Old Stone Inn"
I was needing a place to get away from a hectic life. Old Stone Inn was perfect- within a mile of some good restaurants and still 'remote.' It was rustic, yet comfortable and modern. The breakfast was NOT the typical, bland, complimentary breakfast fare. It was a well-cooked, hot meal- served on white tablecloths in front of a fireplace. Reservations […] had to be made for the evening meal, and people came from all over for that 4 star meal. Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Expedia
"Great quiet location surrounded by trees"
Thoroughly enjoyed our stay. Room was very comfortable. A couple of things that would be helpful additions would be a coffee maker in the room, and refrigerator. The shower pressure was great but made an awful high pitched sound.Αληθινό σχόλιο πελάτη της Hotels.com
"Not Rustic, just out dated."
This is supposed to be a mountain lodge with a rustic feal. The restaurant has a nice mountain lodge atmosphere, just overpriced. As for the location, not removed at all. In fact its in a neighborhood, just plenty of trees to hide it. No views at all, and though its quiet at night the day brings all the noises of a suburban neighborhood. The accomodations […] are quite dated, the couch needed to be replaced as did the carpeting and the old CRT TV. And don't look under the cusions of the couch.......they don't clean there. The staff is VERY friendly and the towels and terry robes are great, with plenty of hot water available. I stayed in a "cottage", it wasn't a cottage but rather a suite so not as private as I had thought. Becareful of the entry road, its very easy to miss and in need of extensive repairs. The facility is a stones throw away from the Waynesville downtown area, which is a must see and the place to go to get your meals or enjoy a drink. Overall, its overpriced for what you get. If you get a deal then try it out! Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Hotels.com
"Similar to Camping Cabin"
We found our room to be very similar to the KOA camping cabins we have stayed in with the addition of our own bathroom. It was very musty smelling and the king sized mattress felt like a sofa bed mattress - not high quality at all. The highlight of the stay was the breakfast served Sunday morning - very good food and good service for the lone server/cook/busperson […] that was working the dining room. The accommodations were not worth the price - unfortunately we would not choose to stay there again. Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Hotels.com
The Old Stone Inn was everything I had hoped for and more - rustic, clean, NOT super shiny-new, but had all the amenties and comforts we needed. We stayed in the Mountain Laurel cottage and it was live having our own priovate treehouse. Back porch was relaxing with peaceful views. The restaurant was gorgeous, service attentive. We will definitely r […] eturn! Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Hotels.com
"off the path"
Its a nice place out of the way, off the main roads. Rocking chains on the porches. It was nice for a few days not to have the same old hotel room. I did not make it to the restaurant.Αληθινό σχόλιο πελάτη της Hotels.com
"Perfect Rustic Place"
It was very nice and fit our expectations perfectly. We were there to get away and do some hiking in the mountains enjoy time away from electronics. If you think of it as a "Hotel" or resort spas type place you will be disappointed but that is not it's purpose. Having said that the rooms are dark and decorated appropriate for a log cabin type room. […] Our room had a couple of chairs for sitting in the room, a separate area with a small shower with a toilet in it. The sink was actually in the room which made it easy for the two of us to get ready. We chose a room with no AC and were very comfortable with open windows and fan in July. Did not have dinner but Breakfast was typical of B&B and hardy. Rockers on porches were nice. Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Hotels.com
"OK for the "simple" stay"
The room was nice and clean however the showerhead was junk and the tub/shower drained slower than the water comes in. I have not stayed at any hotel without an icemaker accessible to guests and there are no vending machines either. The staff at the restaraunt were acommodating with ice during their regular hours. The breakfast at the restaurant that […] was included was adaquate. For the traveler who likes TV, beware, it is small and dated. Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Expedia
"Nice rustic place to stay"
Contrary to the negative reviews I read, Old Stone Inn was a nice place to stay. If you want a 4-star experience, look elsewhere. Rustic totally applies to this place. Queen beds were firm and comfortable. Room was clean, except for dirt dragged in on our feet that stayed on the wooden floors until cleaned in the morning. Shower head didn't move much, […] and for shorter people that prevented a problem in that it'll hit you right in the face. We didn't get to sample the restaurant because of time contraints, however, I did go in and it's gorgeous. The dinner menu looked to be 4 star and I've heard the food is excellent. We WILL be staying here again. Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Hotels.com
"The Old Stone Inn"
We enjoyed our stay there, and our room was quaint and comfortable. The breakfast in the dinning hall was excellent. The overall condition of the Inn needs to be improved, and they have it for sale now. Hopefully a new owner will do renovations.Αληθινό σχόλιο πελάτη της Expedia
"Clean but...."
Mosquitoes in the room, no phone, no clock, no coffee maker, no internet TV was on top of a high chest and was so small (9 inch screen?), window AC didn't cool very well. Also, the pictures that are on the travel site are much better than the hotel itself. Our "view" backed up to trees, no distance views of mountain landscape. It was very clean.Αληθινό σχόλιο πελάτη της Hotels.com
"Just what you want for the mountains!"
This Inn was a pleasant surprise---not a cookie cutter motel at all. Service is excellent room is comfortable and the atmosphere is quaint and relaxing. The restaurant is steps away: Don't miss it! Breakfast is included and was fantastic. We brought a guest to Dinner and that was excellent too.Αληθινό σχόλιο πελάτη της Hotels.com
"Quiet, peaceful stay"
Room was small but clean. Bathroom extremely small, but plenty of hot water. Breakfast served hot and food was excellant. Staff was superb and very friendly.Αληθινό σχόλιο πελάτη της Expedia
"Quaint and Cozy!"
Great place and would stay again. Situated in a residential area which was unexpected, but close to the quaint shops of Waynesville. Breakfast in the lodge was nice and the atmosphere is classy but comfortable. We were able to bring the dog with no questions or problems and enjoyed some walks around the neighborhood. Great place to get away to if you […] want some quiet time! Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Expedia
"The Old Stone Inn Mountain Lodge and Restaurant - a warm and welcoming place to stay"
The Old Stone Inn Lodge and Restaurant is a beautiful comfortable old lodge located (you could say "hidden") in the woods within walking distance of the shops and activities of downtown Waynesville, NC. Imagine - pine-paneled rooms, gas fireplaces, very comfortable beds, a covered balcony with rocking chairs and a woodland view, a full breakfast (included […] in the room price) from a menu, and a cozy/romantic dining room with exceptionally excellent food and service. Rooms even have TVs although we never had an occasion to turn ours on. This lodge is only a short drive from the east-side entrance to the Great Smoky Mountains National Park. The helpful staff gladly provided directions to some little-known off-the-beaten-path parts of the National Park where we visited historical homes of early settlers in the area and saw herds of elk while eating a picnic lunch on the edge of an open field. My wife and I would without hesitation recommend "The Old Stone Inn" to everybody and anybody visiting or traveling through this area. It's a wonderful place to stay. Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Expedia
"Cozy, Rustic Accomodations"
This is a great place if you are looking for a cozy, rustic bed and breakfast. Our room was plain and simple, but clean and comfortable. If you are looking for fancy, this is not it. The restaurant and main structure was built in the 1940's, and retains its original charm. The food was excellent, as well as the service. We enjoyed our stay.Αληθινό σχόλιο πελάτη της Expedia
"Wonderful rustic lodge"
Great wooded setting within the town of Waynesville NC. The knotty pine paneled cottage/room was very clean and well prepared. Plenty of windows with screens that allowed cool air to flow through the room. It also had a gas log fireplace for chili evenings in the fall. The Inn/restaurant's food was impressive. We enjoyed the full breakfast (included) […] and the evening meal choices were incredible! Would recommend to any traveler wanting visit the Waynesville(downtown area has a wondeful shopping experience) Maggie Valley (Wheels Through Time MC Museum-Don't Miss It!) and of course anywhere along the Blue Ridge Parkway. This lodge is conveniently located between the Cherokee and Asheville sections of the Parkway. Perfect for splitting the almost 4 hour drive along the Parkway. Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Expedia
"Great Place for a Getaway!"
We stayed at this lodge August 13, 2011 for one night. After reading some of the negative comments, I was reluctant, but reading the latest reviews which were positive, I decided to take a chance. I was extremely pleased! The room was at the end of the building, clean, with three windows and a King bed, with 2 rocking chairs inside and a ceiling fan […] blowing. If you like the rustic look, this is the place for you. We had the windows open all night with perfect temperatures and just using the ceiling fan. The bed was comfortable and enjoyed sitting outside our door in the rocking chairs. So quiet and peaceful. It's tucked back from the road, and although there is a sign off the main road, and when you turn on Dolan its just down the street on your left. Has a high post sign in front of the dirt drive and the Inn is tucked back in to the woods so you have to look up for the sign since not hanging car level. We didn't get a chance to eat dinner, however, many cars came in for the restaurant. Our room rate included breakfast, which was very good and everyone there was very friendly...and definitely can't wait to go back again! If you want a fancy place this isn't it..but if you are wanting a laid back place with southern hospitality...this place is ideal! Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Expedia
Ο / η επισκέπτης δεν άφησε σχόλιο.Αληθινό σχόλιο πελάτη της Hotels.com
"Wechselnde Güte"
Stilvolle Holzhütte, bereits etwas abgewohnt. Viel Brimborium beim Frühstück, das von einer sehr netten Bedienung serviert wurde, aber sicher nicht jeden Geschmack trifft. Buffet mit ähnlicher, aber individueller Auswahlmöglichkeit wäre ansprechender gewesen. Trotzdem, um Längen besseres Frühstück als im Standardmotel, was bei dem Preis auch erwartet […] werden kann. Wirklich nett war die große Veranda, die ausschlaggebend für unsere Buchung war. Eine schlichte Unverschämtheit war die Matraze eines Schlafzimmers, die getrost als durchgelegene Hängematte bezeichnet werden konnte, die Matraze des 2. Bettes war amerikanisch weich, aber ok. Διαβάστε περισσότεραΑληθινό σχόλιο πελάτη της Expedia
Τα σχόλια και οι βαθμολογίες που περιέχονται σε αυτή την ιστοσελίδα αποτελούν υποκειμενικές απόψεις των πελατών και προμηθευτών και δεν εκπροσωπούν ούτε αντικατοπτρίζουν τη θέση της Hotels.com. Η Hotels.com και τα μέρη που εμπλέκονται στην παροχή περιεχομένου σχολίων δε φέρουν ευθύνη για ζημιές οποιουδήποτε είδους προκύπτουν από τη χρήση αυτών των σχολίων
Τώρα παρακολουθούμε αυτό το ξενοδοχείο για τις ημερομηνίες του ταξιδιού σας
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Moments |
Random ImageAbout...I was born in Trieste under the Virgo sign on September 17th, 1971. y first approach to sports was through.... basketball. I used to play in the courtyard behind the Salesians oratory, and I didn't do bad, in fact I reached the Propaganda league with the Don Bosco T-shirt. Of course I was also fond of soccer - at the time I rooted for Triestina- and my dad often took me to see the matches at the legendary Pino Grezar stadium. Continue... |


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Think of a room, any room. A bedroom, guest room, or open-plan kitchen? In a summerhouse, chic apartment, or family home? Now just add BeoSound 8 to fill up your room with Bang & Olufsen sound and style. If you keep your music on an iPad, iPhone, iPod or computer, you are all set to discover the iconic style and breathtaking sound quality that has made Bang & Olufsen one of the most sought-after names in home audio.
Playing music from your own phone, computer, or media player gives you the advantage of a familiar navigation environment. In addition, you can now download an app version of the sleek and stylish BeoPlayer for your docked iPad, iPhone, or iPod. You can also adjust sound levels and skip tracks quickly and conveniently on BeoSound 8 itself. Music on a docked or USB linked device can be controlled via the dedicated round remote control or of course your existing Beo4 or Beo6 remote controls if you already own other Bang & Olufsen equipment.
To match your personal taste and the room you place it in, BeoSound 8 comes in either black or white with aluminium details and matching power cord. When you feel the need to add a splash of colour to the room, the list of options includes six fabric speaker covers in yellow, orange, red, silver, black and white.
BeoSound 8 offers you a number of additional connection options that give you added flexibility and enjoyment.
Think the only use for BeoSound 8 is as a docking station? Well, think again. Consider it a docking station with flexible connection options designed for how you live.
Need a powerful speaker for your PC or Mac? Simply connect your BeoSound 8, and voilà. You'll hear full, rich sound from your computer as you never have before. And, you'll appreciate the beauty that the attractive BeoSound 8 will add to your setup as well.
Want to hear music on BeoSound 8 without having to dock your iPhone? With Airport Express, it's easy to use your phone without it having to be tied down during docking. You and your phone can relax on the couch, while you continue to enjoy your favourite tunes.
For the best possible sound in any placement, BeoSound 8 is equipped with Bang & Olufsen's unique room adaptation switch
BeoSound 8 offers flexible placement options to fit easily in your living space. You can hang it on a wall using a custom wall bracket or place it on a side table, where the speakers will appear to float millimetres above the surface. The conical speaker backs are excellent if you prefer to place your BeoSound 8 in a corner. But a loudspeaker's performance is strongly influenced by its physical position in the room, and a corner placement can be especially difficult, as the walls will tend to "play along", muddling the bass level in particular. Luckily, Bang & Olufsen has a solution.
BeoSound 8 can be adjusted to its placement by means of a manual position switch, which adjusts the speakers' performance according to whether the system is placed in a corner, against a wall, or standing freely. The three switch positions will change the equalization of primarily the bass channel according to a room response target based on a large number of measurements taken in different positions in different rooms.
This unique Bang & Olufsen feature was introduced to ensure accurate sound reproduction at all times with complete freedom of placement.
BeoSound 8 benefits from advanced acoustical know-how and exclusive technologies to deliver big sound from small speakers. ABL is a Bang & Olufsen patented solution basically to get more bass in small spaces. It is a solution where we make use of the surplus capacity in the built-in amplifiers and driver units at normal listening levels, for a bass extension. With this, we get more bass than the loudspeaker would otherwise be able to produce. However, this solution entails a risk that the driver unit might not be able to handle the extra boosts at higher volume levels. To solve this, we have introduced an electric circuit to monitor the sound level, so when the music peaks in the lower frequency areas and maybe come close to distorting the sound quality or damaging the driver unit, the bass signal is reduced accordingly
Bang & Olufsen developed Adaptive Bass Linearisation for high-end speakers like BeoLab 9, building a reputation for big and authoritative sound from relatively small speaker cabinets.
Download a free customised app to transform the interface on your docked device with matching Bang & Olufsen style.
Now you can go anywhere and take along Bang & Olufsen's exclusive design and superb ease of use on your iPhone, iPad or iPod touch. When you return home, all that changes is the volume and fullness of the sound that surrounds you as you dock your player in BeoSound 8.
The BeoPlayer app available via iTunes puts superior music browsing, thousands of internet radio stations, and an advanced alarm clock right in your pocket. The free version gives you 20 great stations to choose from, with the option to upgrade to more than 13,000 internet radio stations from around the world. Besides advanced scheduling options, the alarm clock gives you a choice between the gentle chime or waking to the sound of music.
Feel at home with Bang & Olufsen – wherever you are.
The BeoPlayer app transforms the look and experience of your iPhone, iPad or iPod touch to match your Bang & Olufsen system. When docked in BeoSound 8, the BeoPlayer application adds internet radio and the elegant and colourful clock design you may know from the BeoCom 5 to your device allowing you to wake up to a gentle chime or your favourite radio station. ou can even customise the colour of the clock to match the front fabric of the speakers. A complete package of design, consistency and convenience.
The docking brace on BeoSound 8 adapts to accommodate a range of devices from a slim iPod touch, iPhone, or iPod to the bulkier iPad. No other docking station on the market supports iPad this elegantly.
"Made for iPod,", "Made for iPhone," and "Made for iPad" means that an electronic accessory has been designed to connect specifically to iPod, iPhone or iPad respectively, and has been certified by the developer to meet Apple Performance Standards. Apple is not responsible for the operation of this device or its compliance with safety and regulatory standards. Please note that the use of this accessory with iPod, iPhone or iPad may affect wireless performance. Made for iPhone®, iPod® and iPad™ iPod Shuffle, iPod nano, iPod classic, iPod touch and iPhone are trademarks of Apple Inc., registered in the U.S. and other countries. iPad is a trademark of Apple Inc.


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NCI/PDQ® Health professionals: Genetics of Breast and Ovarian Cancer (PDQ®) | |||||||||
National Cancer Institute | |||||||||
Last Modified: December 21, 2012 |
[Note: Many of the medical and scientific terms used in this summary are found in the NCI Dictionary of Genetics Terms. When a linked term is clicked, the definition will appear in a separate window.] [Note: Many of the genes and conditions described in this summary are found in the Online Mendelian Inheritance in Man (OMIM) database. When OMIM appears after a gene name or the name of a condition, click on OMIM for a link to more information.] Among women, breast cancer is the most commonly diagnosed cancer after nonmelanoma skin cancer, and it is the second leading cause of cancer deaths after lung cancer. In 2012, an estimated 229,060 new cases will be diagnosed, and 39,920 deaths from breast cancer will occur. 1 The incidence of breast cancer, particularly for estrogen receptorpositive cancers occurring after age 50 years, is declining and has declined at a faster rate since 2003; this may be temporally related to a decrease in hormone replacement therapy (HRT) following early reports from the Women's Health Initiative. 2 Ovarian cancer is the ninth most common cancer, with an estimated 22,280 new cases in 2012, but is the fifth most deadly, with an estimated 15,500 deaths in 2012. 1 (Refer to the PDQ® summaries on Breast Cancer Treatment and Ovarian Epithelial Cancer Treatment for more information on breast cancer and ovarian cancer rates, diagnosis, and management.) A possible genetic contribution to both breast and ovarian cancer risk is indicated by the increased incidence of these cancers among women with a family history (see the Family History as a Risk Factor for Breast Cancer and the Family History as a Risk Factor for Ovarian Cancer sections below), and by the observation of some families in which multiple family members are affected with breast and/or ovarian cancer, in a pattern compatible with an inheritance of autosomal dominant cancer susceptibility. Formal studies of families (linkage analysis) have subsequently proven the existence of autosomal dominant predispositions to breast and ovarian cancer and have led to the identification of several highly penetrant genes as the cause of inherited cancer risk in many families. (Refer to the PDQ® summary Cancer Genetics Overview for more information on linkage analysis.) Mutations in these genes are rare in the general population and are estimated to account for no more than 5% to 10% of breast and ovarian cancer cases overall. It is likely that other genetic factors contribute to the etiology of some of these cancers.
In cross-sectional studies of adult populations, 5% to 10% of women have a mother or sister with breast cancer, and about twice as many have either a first-degree relative (FDR) or a second-degree relative with breast cancer. 3 4 5 6 The risk conferred by a family history of breast cancer has been assessed in both case-control and cohort studies, using volunteer and population-based samples, with generally consistent results. 7 In a pooled analysis of 38 studies, the relative risk (RR) of breast cancer conferred by an FDR with breast cancer was 2.1 (95% confidence interval [CI], 2.02.2). 7 Risk increases with the number of affected relatives, age at diagnosis, and the number of affected male relatives. 4 5 7 8 (Refer to the Penetrance of mutations section of this summary for a discussion of familial risk in women from families with BRCA1/BRCA2 mutations who themselves test negative for the family mutation.)
Although reproductive, demographic, and lifestyle factors affect risk of ovarian cancer, the single greatest ovarian cancer risk factor is a family history of the disease. A large meta-analysis of 15 published studies estimated an odds ratio (OR) of 3.1 for the risk of ovarian cancer associated with at least one FDR with ovarian cancer. 9
Autosomal dominant inheritance of breast/ovarian cancer is characterized by transmission of cancer predisposition from generation to generation, through either the mother's or the father's side of the family, with the following characteristics:
Breast and ovarian cancer are components of several autosomal dominant cancer syndromes. The syndromes most strongly associated with both cancers are the BRCA1 or BRCA2 mutation syndromes. Breast cancer is also a common feature of Li-Fraumeni syndrome due to TP53 mutations and of Cowden syndrome due to PTEN mutations. 10 Other genetic syndromes that may include breast cancer as an associated feature include heterozygous carriers of the ataxia telangiectasia (AT) gene and Peutz-Jeghers syndrome. Ovarian cancer has also been associated with Lynch syndrome, basal cell nevus (Gorlin) syndrome (OMIM), and multiple endocrine neoplasia type 1 (MEN1) (OMIM). 10 Germline mutations in the genes responsible for those syndromes produce different clinical phenotypes of characteristic malignancies and, in some instances, associated nonmalignant abnormalities. The family characteristics that suggest hereditary breast and ovarian cancer predisposition include the following:
There are no pathognomonic features distinguishing breast and ovarian cancers occurring in BRCA1 or BRCA2 mutation carriers from those occurring in noncarriers. Breast cancers occurring in BRCA1 mutation carriers are more likely to be estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2/neu receptor-negative and have a basal phenotype. BRCA1-associated ovarian cancers are more likely to be high grade and of serous histopathology. (Refer to the Pathology of breast cancer and Pathology of ovarian cancer sections of this summary for more information.)
When using family history to assess risk, the accuracy and completeness of family history data must be taken into account. A reported family history may be erroneous, or a person may be unaware of relatives affected with cancer. In addition, small family sizes and premature deaths may limit the information obtained from a family history. Breast or ovarian cancer on the paternal side of the family usually involves more distant relatives than on the maternal side and thus may be more difficult to obtain. When comparing self-reported information with independently verified cases, the sensitivity of a history of breast cancer is relatively high, at 83% to 97%, but lower for ovarian cancer, at 60%. 11 12
Other risk factors for breast cancer include age, reproductive and menstrual history, hormone therapy, radiation exposure, mammographic breast density, alcohol intake, physical activity, anthropometric variables, and a history of benign breast disease. (Refer to the PDQ® summary on Breast Cancer Prevention for more information.) These factors, including their role in the etiology of breast cancer among BRCA1/BRCA2 mutation carriers, are considered in more detail in other reviews. 13 14 15 Brief summaries are given below, highlighting, where possible, the effect of these risk factors in women who are genetically susceptible to breast cancer. (Refer to the Clinical management of BRCA mutation carriers section of this summary for more information about their effects in BRCA1/BRCA2 mutation carriers.) Cumulative risk of breast cancer increases with age, with most breast cancers occurring after age 50 years. 16 In women with a genetic susceptibility, breast cancer, and to a lesser degree, ovarian cancer, tends to occur at an earlier age than in sporadic cases.
In general, breast cancer risk increases with early menarche and late menopause and is reduced by early first full-term pregnancy. In BRCA1 and BRCA2 mutation carriers, results have been conflicting and may be gene dependent. No consistent significant associations have been observed. 15 17 18 19 Evidence suggests that reproductive history may be differentially associated with breast cancer subtype (i.e., triple-negative vs. ER-positive breast cancers). In contrast to ER-positive breast cancers, parity has been positively associated with triple-negative disease, with no association with ages at menarche and menopause. 20 Oral contraceptives (OCs) may produce a slight increase in breast cancer risk among long-term users, but this appears to be a short-term effect. In a meta-analysis of data from 54 studies, the risk of breast cancer associated with OC use did not vary in relationship to a family history of breast cancer. 21 OCs are sometimes recommended for ovarian cancer prevention in BRCA1 and BRCA2 mutation carriers. Although the data are not entirely consistent, a meta-analysis concluded that there was no significant increased risk of breast cancer with OC use in BRCA1/BRCA2 mutation carriers. 22 However, use of OCs formulated before 1975 was associated with an increased risk of breast cancer (summary relative risk [SRR], 1.47; 95% CI, 1.062.04). 22 (Refer to the Reproductive factors section in the Clinical management of BRCA mutation carriers section of this summary for more information.) Data exist from both observational and randomized clinical trials regarding the association between postmenopausal HRT and breast cancer. A meta-analysis of data from 51 observational studies indicated a RR of breast cancer of 1.35 (95% CI, 1.211.49) for women who had used HRT for 5 or more years after menopause. 23 The Women's Health Initiative (WHI), a randomized controlled trial (NCT00000611) of about 160,000 postmenopausal women, investigated the risks and benefits of HRT. The estrogen-plus-progestin arm of the study, in which more than 16,000 women were randomly assigned to receive combined HRT or placebo, was halted early because health risks exceeded benefits. 24 25 Adverse outcomes prompting closure included significant increase in both total (245 vs. 185 cases) and invasive (199 vs. 150 cases) breast cancers (RR, 1.24; 95% CI, 1.021.5, P <. 001) and increased risks of coronary heart disease, stroke, and pulmonary embolism. Similar findings were seen in the estrogen-progestin arm of the prospective observational Million Women's Study in the United Kingdom. 26 The risk of breast cancer was not elevated, however, in women randomly assigned to estrogen-only versus placebo in the WHI study (RR, 0.77; 95% CI, 0.591.01). Eligibility for the estrogen-only arm of this study required hysterectomy, and 40% of these patients also had undergone oophorectomy, which potentially could have impacted breast cancer risk. 27 The association between HRT and breast cancer risk among women with a family history of breast cancer has not been consistent; some studies suggest risk is particularly elevated among women with a family history, while others have not found evidence for an interaction between these factors. 28 29 30 31 32 23 The increased risk of breast cancer associated with HRT use in the large meta-analysis did not differ significantly between subjects with and without a family history. 32 The WHI study has not reported analyses stratified on breast cancer family history, and subjects have not been systematically tested for BRCA1/BRCA2 mutations. 25 Short-term use of hormones for treatment of menopausal symptoms appears to confer little or no breast cancer risk. 23 33 The effect of HRT on breast cancer risk among carriers of BRCA1 or BRCA2 mutations has been studied only in the context of bilateral risk-reducing oophorectomy, in which short-term replacement does not appear to reduce the protective effect of oophorectomy on breast cancer risk. 34 (Refer to the Hormone replacement therapy in BRCA1/BRCA2 mutation carriers section of this summary for more information.) Observations in survivors of the atomic bombings of Hiroshima and Nagasaki and in women who have received therapeutic radiation treatments to the chest and upper body document increased breast cancer risk as a result of radiation exposure. The significance of this risk factor in women with a genetic susceptibility to breast cancer is unclear. Preliminary data suggest that increased sensitivity to radiation could be a cause of cancer susceptibility in carriers of BRCA1 or BRCA2 mutations, 35 36 37 38 and in association with germline ATM and TP53 mutations. 39 40 The possibility that genetic susceptibility to breast cancer occurs via a mechanism of radiation sensitivity raises questions about radiation exposure. It is possible that diagnostic radiation exposure, including mammography, poses more risk in genetically susceptible women than in women of average risk. Therapeutic radiation could also pose carcinogenic risk. A cohort study of BRCA1 and BRCA2 mutation carriers treated with breast-conserving therapy, however, showed no evidence of increased radiation sensitivity or sequelae in the breast, lung, or bone marrow of mutation carriers. 41 Conversely, radiation sensitivity could make tumors in women with genetic susceptibility to breast cancer more responsive to radiation treatment. Studies examining the impact of mammography and chest x-ray exposure in BRCA1 and BRCA2 mutation carriers have had conflicting results. 42 43 (Refer to the Mammography section of this summary for more information about radiation.) The risk of breast cancer increases by approximately 10% for each 10 g of daily alcohol intake (approximately one drink or less) in the general population. 44 45 Prior studies of BRCA1/BRCA2 mutation carriers have found no increased risk associated with alcohol consumption. 46 47
Weight gain and being overweight are commonly recognized risk factors for breast cancer. In general, overweight women are most commonly observed to be at increased risk of postmenopausal breast cancer and at reduced risk of premenopausal breast cancer. Sedentary lifestyle may also be a risk factor. 48 These factors have not been systematically evaluated in women with a positive family history of breast cancer or in carriers of cancer-predisposing mutations, but one study suggested a reduced risk of cancer associated with exercise among BRCA1 and BRCA2 mutation carriers. 49
Benign breast disease (BBD) is a risk factor for breast cancer, independent of the effects of other major risk factors for breast cancer (age, age at menarche, age at first live birth, and family history of breast cancer). 50 There may also be an association between BBD and family history of breast cancer. 51 An increased risk of breast cancer has also been demonstrated for women who have increased density of breast tissue as assessed by mammogram, 50 52 53 and breast density is likely to have a genetic component in its etiology. 54 55 56 Other risk factors, including those that are only weakly associated with breast cancer and those that have been inconsistently associated with the disease in epidemiologic studies (e.g., cigarette smoking), may be important in women who are in specific genotypically defined subgroups. For example, some studies have suggested that certain N-acetyl transferase alleles may influence female smokers' risk of developing breast cancer. 57 One study 58 found a reduced risk of breast cancer among BRCA1/BRCA2 mutation carriers who smoked, but an expanded follow-up study failed to find an association. 59
Factors that increase risk of ovarian cancer include increasing age and nulliparity, while those that decrease risk include surgical history and use of OCs. 60 61 (Refer to the PDQ® summary on Prevention of Ovarian Cancer for more information.) Relatively few studies have addressed the effect of these risk factors in women who are genetically susceptible to ovarian cancer. (Refer to the Reproductive factors section of this summary for more information.) Ovarian cancer incidence rises in a linear fashion from age 30 years to age 50 years and continues to increase, though at a slower rate, thereafter. Before age 30 years, the risk of developing epithelial ovarian cancer is remote, even in hereditary cancer families. 62 Nulliparity is consistently associated with an increased risk of ovarian cancer, including among BRCA1/BRCA2 mutation carriers. 63 Risk may also be increased among women who have used fertility drugs, especially those who remain nulligravid. 60 64 Evidence is growing that the use of menopausal HRT is associated with an increased risk of ovarian cancer, particularly in long-time users and users of sequential estrogen-progesterone schedules. 65 66 67 68 Bilateral tubal ligation and hysterectomy are associated with reduced ovarian cancer risk, 60 69 70 including in BRCA1/BRCA2 mutation carriers. 71 Ovarian cancer risk is reduced more than 90% in women with documented BRCA1 or BRCA2 mutations who chose risk-reducing salpingo-oophorectomy (RRSO). In this same population, prophylactic removal of the ovaries also resulted in a nearly 50% reduction in the risk of subsequent breast cancer. 72 73 (Refer to the Risk-reducing salpingo-oophorectomy section of this summary for more information about these studies.) Use of OCs for 4 or more years is associated with an approximately 50% reduction in ovarian cancer risk in the general population. 60 61 A majority of, but not all, studies also support OCs being protective among BRCA1/ BRCA2 mutation carriers. 63 74 75 76 77 A meta-analysis of 18 studies including 13,627 BRCA mutation carriers reported a significantly reduced risk of ovarian cancer (SRR, 0.50; 95% CI, 0.330.75) associated with OC use. 22 (Refer to the Oral contraceptives section in the Chemoprevention section of this summary for more information.)
Models to predict an individual's lifetime risk of developing breast cancer are available. 78 79 In addition, models exist to predict an individual's likelihood of having a BRCA1 or BRCA2 mutation. (Refer to the Models for prediction of the likelihood of a BRCA1 or BRCA2 mutation section of this summary for more information about these models.) Not all models can be appropriately applied for all patients. Each model is appropriate only when the patient's characteristics and family history are similar to the study population on which the model was based. Different models may provide widely varying risk estimates for the same clinical scenario, and the validation of these estimates has not been performed for many models. 79 80 Table 1 summarizes the salient aspects of two of the common risk assessment models and is designed to aid in choosing the model that best applies to a particular individual. The Claus model 81 82 and the Gail model 83 are widely used in research studies and clinical counseling. Both have limitations, and the risk estimates derived from the two models may differ for an individual patient. Several other models, which include more detailed family history information, are also in use and are discussed below.
The Gail and the Claus models will significantly underestimate breast cancer risk in women from families with hereditary breast cancer susceptibility syndromes. Generally, the Claus or the Gail models should not be the sole model used for families with one or more of the following characteristics:
The Gail model is the basis for the Breast Cancer Risk Assessment Tool, a computer program that is available from the National Cancer Institute by calling the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237 or TTY at 1-800-332-8615). This version of the Gail model estimates only the risk of invasive breast cancer. The Gail model has been found to be reasonably accurate at predicting breast cancer risk in large groups of white women who undergo annual screening mammography; however, reliability varies based on the cohort studied. 88 89 90 91 92 93 Risk can be overestimated in: Risk could be underestimated in the lowest risk strata. 92 Earlier studies 89 90 suggested risk was overestimated in younger women and underestimated in older women. More recent studies 91 92 using the modified Gail model (which is currently used) found it performed well in all age groups. Further studies are needed to establish the validity of the Gail model in minority populations. 93 Recently, modifications have been made to the Breast Cancer Risk Assessment Tool incorporating data from the Women's Contraceptive and Reproductive Experiences (CARE) study. This study of more than 1,600 African American women with invasive breast cancer and more than 1,600 controls was used to develop a breast cancer risk assessment model with improved race-specific calibration. 87 Additional information for seven common low-penetrance breast cancer susceptibility alleles has not been shown to improve model performance significantly. 94 95 A study of 491 women aged 18 to 74 years with a family history of breast cancer compared the most recent Gail model to the Claus model in predicting breast cancer risk. 96 The two models were positively correlated (r = .55). The Gail model estimates were higher than the Claus model estimates for most participants. Presentation and discussion of both the Gail and Claus models risk estimates may be useful in the counseling setting. The Tyrer-Cuzick model incorporates both genetic and nongenetic factors. 97 A three-generation pedigree is used to estimate the likelihood that an individual carries either a BRCA1/BRCA2 mutation or a hypothetical low penetrance gene. In addition, the model incorporates personal risk factors such as parity, body mass index, height, and age at menarche, menopause, HRT use, and first live birth. Both genetic and nongenetic factors are combined to develop a risk estimate. Although powerful, the model at the current time is less accessible to primary care providers than the Gail and Claus models. The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) model examines family history to estimate breast cancer risk and also incorporates both BRCA1/BRCA2 and non-BRCA1/BRCA2 genetic risk factors. 98 Other risk assessment models incorporating breast density have been developed but are not ready for clinical use. 99 100 In the future, additional models may be developed or refined to include such factors as breast density and other biomarkers. References:


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Ohio's elections chief said Thursday a first-of-its-kind statewide review found instances of voter fraud in the battleground state during last year's presidential election but not rampant abuses. More>>
Ohio's Republican U.S. senator is demanding to know if any disciplinary action has been taken against IRS employees at the agency's Cincinnati office for targeting conservative groups. More>>
Ohio officials are warning that federal budget cuts are going to put a dent in public health programs. More>>
A proposed constitutional amendment legalizing medical marijuana and certain uses of hemp has cleared Ohio's ballot board. More>>
Democrats in the Ohio House are proposing a series of reforms they say will make Gov. John Kasich's (KAY'-siks) private nonprofit job-creation office, JobsOhio, more accountable to the public. More>>
The controversial third-grade guarantee has been a heated topic since it passed last July, but new legislation would give teachers more options. More>>
The Franklin County Board of Elections will most likely have to recount votes for the Groveport Madison tax levy. More>>


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Love this shoe...it's easy to put on, goes with everything and can be casual or a little more dressy. No break in time needed!
A breath of fresh air the Lorelei Emme walks the walk with refreshing style and function. Flexible mesh and leather upper and stride specific Merrell QForm® Comfort midsole creates total walking comfort.
• Combination construction delivers stability in the heel and flexibility in the forefoot
• Full grain leather and mesh upper
• Breathable mesh lining treated with Aegis® antimicrobial solution resists odor
• EVA removable footbed
• Molded nylon arch shank
• Compression molded EVA footframe for stability and comfort
• Merrell QForm® Comfort midsole provides women's specific stride-sequenced cushioning
• Merrell air cushion in the heel absorbs shock and adds stability
• 1.0 mm sole lug depth
• Merrell Lorelei Sole / Sticky Rubber
Women's Weight: 14 ozs
Love this shoe...it's easy to put on, goes with everything and can be casual or a little more dressy. No break in time needed!
Awesome to hear you were able to just slip these on right out of the box and go! Thank you so much for your review and we are so glad you find them to go great with everything.
Sized as Expected
casual daily life
An attractive shoe--comfortable, fits well. I bought gray which is a lovely, soft color for spring, goes with everything.
These will be great for spring. We are so happy you love the fit and comfort of these breathable, light weight shoes. Thank you for the feedback.
Sized as Expected
Casual, semi-dressy
I walk very long distances, and the Merrell's Lorelei Emme is the perfect shoe for me. It's mesh fabric means that my feet are well-ventilated. The shoe doesn't have a lot of built-in support, so it is almost like walking barefooted. Since I can no longer find the Merrell Circuit MJ Breeze, this is a great replacement shoe.
Thank you for your great recommendation on a replacement style for the Circuit MJ Breeze. Glad this shoe fits all of your needs for a walking shoe. Thank you for your review.
Sized as Expected
Walking every day.
These shoes are great! Comfy and very light weight. Hardly know they are on your feet.
Thank you for your feedback! It is terrific to know that you find them to be very comfy and light weight on your feet.
Sized as Expected
I bought a pair of black Loreleis last May before my family went on vacation. We were at a theme park for a week and I wore them everywhere. And then I came home and eight months later I'm still wearing them everywhere and they still look good. They are comfortable and supportive enough to walk around in all day and are cute enough for working in an office. I'm trying to convince my husband that I need another pair.
It sounds like you found the perfect shoe for both work and play. Thank you for the fabulous review and we are thrilled they are super comfortable even for all day use.
Sized as Expected


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The newly changed and redone background was customized by a combination of information. We cannot disclose the methods to the madness, but now that the method has been proven to be effective, we will explore and implement other changes later down the road. Digital Blasphemy was the source for the background change.
As Tupac said, "It never stops, when my mama ask me will I change, I tell her yeah, but it's clear I'll always be the same, until the end of time." Change is sometimes inevitable, sometimes it is planned and sometimes it is unexpected. The first black President campaigned on changes. His intentions were good, but it was impossible for him to fix 30 years of downhill chaos in 4 years of endless redtape.
The minute we stop changing is the minute that we fall behind. Adapting is a very important ability to have. Most of us don't like changes. We get comfortable and when we find things has changed, we tend to panic because we have become used to the way things were. Life is short, change is good, until the end of time. Tupac was one who understood that resisting change would eventually cause society to eventually accept change. This sign below is not directed at Barack Obama, but the United States is ranked #24 on the list of LEAST corrupt nations, while Hong Kong and Qatar are higher on the list. Does that not say something about the U.S.? The United States of America has seen better days. Long gone are the peace love and happiness of the 70s. Long gone is the rock and roll musical revolution of the 80s. Long gone is the Technology gold rush of the 90s. After Y2K, everything went downhill in a slippery slope, unstoppable like an avalanche. The problem is that people don't like change, and THIS is what happens, when you don't change, you end up looking like this:
Change can sometimes be a lonely road, but breaking the cycle from everyday life is sometimes critical to emotional well being. Logo designs change, website ownerships change, places change. Make the most of it, accept it, and learn from it!


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Updated CLOSET TOUR & Organization Tips
25 comments:
Oh my gosh, your closet is amazing! I totally agree with what you said in the video about how having too many clothes stresses you out. I feel the exact same way and probably have the same amount of clothes and accessories as you: not an extremely excessive amount, but enough that I can achieve the varied and versatile style I'm after. Thanks for the organization inspiration...from a fellow perfectionist!
- Samantha
http://samlovesmakeup.wordpress.comGreat post Tiffany! I love seeing how other people organize their closets! :) I have been watching you on youtube for years and recently started following your blog. You seem like such a sweet guru! You are kind to your readers/viewers and I really appreciate that! If you don't mind I would LOVE if you check out my blog! Hope you are having a good day!
xx VeronicaHi Tiffany,
I became a follower of your blog not that long ago, but fell in love with it since I am an American ex-pat living in Spain and fellow new beauty and fashion blogger.
I loved your entry on closet organization. The Container Store is definately one of my all time favorite places to get amazing things to sort my life out.
I gave your blog a prize and hope you will stop by my corner and pick it up :) I'd love to have you as a follower if you find any of it interesting!
Take care,
http://lanielovespink.blogspot.com/such a nice post..leant so much about closet tour and Organization Tips..facial masks
ReplyDeleteI love your blog and often find myself emailing my sisters about your reviews, etc. Quick question, have you done or can you do a post on waxing (upper lip hair). Just curious on what you do, if you do anything. Thanks :-)
cheap prom dressesHey, you have a lovely closet and a good collection of clothes, footwear etc.
One thing I usually take care of is that the storage should not be too high that I would have to climb up to reach it. Everything should be easily accessible. It's always good to get our closets done by expert closet organizers .Very nice and helpful information has been given in this post. I like the way you explain the things. Keep posting. Thanks!
Closet Organizer


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NASHVILLE, Tenn. (AP) — Jake Locker believes the best way to be a leader is by doing, not talking.
RENTON, Wash.
RENTON, Wash. (AP) — It shouldn't be a surprise that Jordan Hill and Jesse Williams are roommates during the Seattle Seahawks rookie minicamp.
SEATTLE (AP) — Former Seattle Seahawks linebacker Leroy Hill won't face a felony charge in his January arrest for investigation of domestic
STATE COLLEGE, Pa.
MINNEAPOLIS (AP) — The Vikings released punter Chris Kluwe on Monday, bringing an end to his colorful and outspoken eight-year stay in Minnesota.
JACKSONVILLE, Fla.
ALAMEDA, Calif.
EDEN PRAIRIE, Minn.
ALLEN PARK, Mich.
RENTON, Wash. (AP) — The Seattle Seahawks have used their third pick in the fifth round of the NFL draft on Rice tight end Luke Willson.
RENTON, Wash. (AP) — John Schneider threw in another surprise at a position where the Seattle Seahawks appeared set.
TAMPA, Fla. (AP) — If Josh Freeman isn't Tampa Bay's long-term solution at quarterback, the Buccaneers are hoping they've found an alternative.


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Atlanta had a potential scoring opportunity interrupted by the call, which then developed into a 19-minute delay before play continued.
The Cardinals were leading, 6-3, at the time, and Andrelton Simmons came up with runners on first and second. Simmons lifted a fly ball into short left field, and two St. Louis defenders — shortstop Peter Kozma and left fielder Matt Holliday — converged on the ball.
Kozma wound up pulling up at the last second, and Holliday wasn't in position to make the catch. The ball dropped, but left-field umpire Sam Holbrook immediately signaled for the infield fly rule. Braves manager Fredi Gonzalez protested, and fans in the crowd pelted the playing surface with litter.
"For me, that's uncalled for," said Gonzalez. "I think we, as fans, and I understand. I understand the disappointment. But we can't do that. As Atlanta Braves and people from Georgia, it doesn't look good, and I'm a little disappointed in our fans from that point."
The umpire's ruling meant that the batter was ruled out. Gonzalez filed an official protest with the umpiring crew, and the stadium waited while the situation was sorted out.
The inning ended with a bases-loaded strikeout by Michael Bourn.
Kozma was perhaps 90 feet onto the outfield grass when the ball dropped between he and the charging Holliday, and the umpire's arm didn't go up to indicate the infield fly rule until a moment before the ball hit the ground.
The Major League rulebook clearly states the circumstances of the infield fly rule.
"An infield fly is a fair fly ball (not including a line drive nor an attempted bunt) which can be caught by an infielder with ordinary effort, when first and second, or first, second and third bases are occupied, before two are out," says Rule 2.00 in the definition of terms. "The pitcher, catcher and any outfielder who stations himself in the infield on the play shall be considered infielders for the purpose of this rule."
A further comment on that official rule spells out the complexity of making the call.
"The umpire is to rule whether the ball could ordinarily have been handled by an infielder -- not by some arbitrary limitation such as the grass, or the base lines," it says. "The umpire must rule also that a ball is an infield fly, even if handled by an outfielder, if, in the umpire's judgment, the ball could have been as easily handled by an infielder.
"The infield fly is in no sense to be considered an appeal play. The umpire's judgment must govern, and the decision should be made immediately."
Torre, Major League Baseball's executive vice president of baseball operations, addressed the protest after the game.
"I talked to Jeff Kellogg during the play stoppage because of the unique situation with the one-game playoff," he said. "He just was curious how to handle the protest. In looking at the rule, there's 24 hours you have to make the report. In the circumstances, I think, it just didn't make sense for that to take place. So after the game, I made sure I talked to both Frank Wren and Fredi to let them know that I was disallowing the protest. I wanted to make sure they heard it from me.
"I like the one-game playoff. It's a Game 7. This was an exciting game. I mean, I'm sorry about the controversy. It's certainly not something we ever planned on. But two out of three, a number of different reasons I don't like that. A two out of three, you've got to make an off-day somewhere. You could having a team win the division and [sit still] for five or six days."


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But it all started in another country - Australia. Malik was there to play the third Test in their series against Australia. And Sania was playing in the Hobart Open. Sources have said that these two were staying in the same hotel, which is where the first sparks ignited, and they decided to keep in touch. The lovebirds then met again in Dubai in February. Sania was there to play the Dubai WTA Tennis Championships and Malik was part of the Pakistan team involved in a two-T20 match series against England. In a month's time, it was confirmed that they'd be getting married in April. The Indo-Pak pair intends to settle down in Dubai after their wedding.
"My wedding is, Inshallah, going to be the biggest day of my life. I've been in constant media glare, I'd appreciate some privacy," Sania said on a TV channel, with her dad, Imran Mirza, adding, "This is a unique case where husband and wife will represent their respective countries in sport." "Thanks for all your support. And the news of me marrying Sania is true. Inshallah, we will get married in April," tweeted Malik.
Mirza family sources confirmed that Malik's mother flew down to Hyderabad three weeks ago and "convinced" Sania's father and mother for the union. Shoaib's mother told the Mirzas that she wouldn't interfere in the life of the son and daughter-in-law, and that Sania could play tennis for as long as she wants. Another reason the parents agreed was that Shoaib and Sania will be living in Dubai post marriage, as Shoaib is a citizen of Dubai.
The wedding will be in India and the reception in Lahore. Sources say Shoaib's family will arrive in Hyderabad from Pakistan on April 7, and Shoaib on April 10 from Dubai, for the engagement. Reports say the engagement would either be on April 10, or the engagement and wedding will take place on April 14, within 24 hours of each other. The couple didn't want to have a long engagement period considering both have had failed engagements in the past. The reception's supposed to take place in the Pearl Continental or Avari Hotel in Lahore.
It may be recalled that Sania cancelled her engagement with childhood friend Mohammed Sohrab Mirza in January this year. Shoaib had gotten engaged to a Hyderabadi girl, Ayesha Siddiqui, in 2002, but snapped ties over the phone later. Her father, Ahmed Siddiqui, had even threatened to sue Malik in court and seek legal divorce. But Malik alleged that the family was trying to fleece him and stated in Karachi that no nikaah had taken place between him and Ayesha.
Malik's friendship with actress Sayali Bhagat had also generated controversy.Imran Zafar Malik, Shoaib's brother-in-law, told DT, "Sab ghar pe bahut khush hain. Aap bataiye, aapke desh mein kaisa reaction hai? We'll all be in India in April to be part of the wedding."
Thursday, April 01, 2010
Salman had re .....more
"My wife made me come because she hadn't been here before. I'd been putting .....more
concept, something that will surely promote better understanding between the neighbours
Imagine. Wasim Ak .....more
All heart. That's the only phrase to describe Brijmohan Lall Munjal's extraordinarily mo .....more
Page 154 of 178
Special Editions
The News on Sunday Special Report: India Pakistan prisoners more editions
We probably didn't need to do this Special Report. Newspaper stories don't matter when it comes to Indians in Pakistani jails and vice versa. In fact, 'vice versa' sums it up. We do to them what they do to us.
Except when the two countries decide to begin talking, yet again! This time a little before the foreign secretary level talks, some Pakistani prisoners were released by India (and vice versa must have happened) and some more were release....read more
For the past 2 years the Jang Group and Geo have been working on a project of great national interest; one that we hope will help usher in an era of peace and prosperity in the country and indeed, in the region. And one that hopefully all Pakistanis can be proud of. more
The Jang Group has entered into an agreement with the Times of India Group, the largest media group of India, to campaign for peace betw
Global Media


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I picked the first of the season today and it is starting to look very promising for the rest of the season. I only picked a little and this will last well in the fridge for as much as a week.
I also picked Sea Purslane, Sea Beet Orache & Sea Blite but I don't have pictures of those!


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Purely4kids is the baby of two mums (we have 6 kids between us) with a passion for kids fashion.
Congratulations you've found the BEST range of Australian designed babies clothes, boys clothes, girls clothes, gifts and accessories! Welcome to purely4kids online childrens boutique!
Have fun shopping at home at a time that suits you! Fall in love with our gorgeous range of baby's, boy's and girl's clothes, which you'll find has a very unique Australian flavour. We're passionate about supporting local designers who are creatively inspiring. Enjoy browsing through our wide selection of high quality, boutique, kids fashion labels.
Purely4kids has got you covered for all designer kids clothing; girls clothes that are oh-so-pretty and boys clothes as tough as them!
Purely4kids named as 2013 Small Business Champion Awards Finalist!
Enjoy Free Shipping Australia Wide on all orders over $65 ..... FREE G...Purely4kids is the baby of two mums (we have 6 kids between us) with a passion for kids fashion.


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Flower Cutout Bag Recycled from Tires
Giving discarded tires and inner tubes a new life, the artisans of Conserve India source and clean the rubber and turn it into a functional stylish bag with bright red floral design cutouts. The slim design and short handles are perfect for tucking the bag under one's arm. The bag is lined with an internal zipper pocket and small open pocket. Sturdy double zipper opening.
- Each bag is unique as tire company logos, scuff marks from use, and stripes and sidewall colors, make each bag one of a kind. These imperfections add to the novelty of the bag.
- As the bag is made from rubber, it will always maintain a slight rubber smell
- The bag can be wiped with tire cleaner but the areas with fabric should be avoided
- A Fair Trade product, all persons involved with its creation make a living wage.
About the Artisan
Born of a desire to reduce India's mountain of waste, improve energy efficiency, and help some of Delhi's poorest out of the city's slums, Conserve India achieves all this by turning plastic bags and rubber into high fashion handbags.
Conserve started as a fledgling recycling project but quickly adapted to confront the biggest challenge it was facing, what to do with the thousands of plastic bags that could not be composted or recycled locally.
After much experimentation, the Conserve team hit upon the idea of not recycling, but upcycling by washing, drying, and pressing the bags into sheets. Handmade Recycled Plastic (HRP) was born and designs for handbags, wallets, shoes and belts quickly came flooding in. The challenge was obvious: Use high fashion to support better lives for the poorest and a cleaner environment for all.


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Allen will retain his post as the commander of U.S. and allied forces in Afghanistan, pending Senate confirmation of a successor, according to the Defense Department. That vote is due Thursday, Senate officials said.
Allen has denied wrongdoing, a senior defense official said.
The investigation into Allen is in its early stages, but authorities are looking into some 20,000 to 30,000 pages of documents, a defense official told CNN. It is not clear how many of those include potentially inappropriate communications.
A U.S. official told CNN on Tuesday that many of the documents could be innocuous, involving routine business that Allen and Kelley were both involved in at the U.S. Central Command.
"In his duties at CENTCOM, Gen. Allen conducted a lot of legitimate business. She (Kelley) did a lot of work with CENTCOM, including Wounded Warriors and such," the official said. "It could be that 29,900 of the documents are legitimate business, and the few remaining raise a few eyebrows."
The potentially inappropriate messages were "flirtatious" in nature, a defense official who has been authorized to speak on the matter told CNN.
Sources familiar with Kelley have said the relationship between the two was not sexual. One said their communications were not of a sexual nature, while another allowed that the e-mails were flirtatious.
That Allen is remaining in command in Afghanistan suggests that there is no criminal issue, another U.S. official told CNN. But the official said the Defense Department's inspector general, an agency watchdog, could still find evidence of criminal conduct.
While the nature of the relationship between Allen and Kelley, if any, is unclear, evidence of an affair could subject the general to military prosecution. Adultery is a violation of military law.
"I think he ought to stay on unless there is some reason put forward that he has done something wrong, and then I think the military leaders will decide then what the actions will be," Sen. Carl Levin, D-Michigan, chairman of the Senate Armed Services Committee, said when asked whether he thought Allen should step down from his Afghanistan job.


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L Space 2013 Blue Fringe Bandeau Bikini
Starting At: $68.00
L Space 2013 Blue Halter Bikini
Starting At: $62.00


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High performance double beam, graphite furnace and dual-atomizer double beam atomic absorption (AA) spectrometers.
Compact, stylish and designed with ease of use as a priority.
Thermo Scientific* iCE* 3300 Atomic Absorption Spectrometer is a compact, easy to use, fully PC controlled flame atomic absorption spectrometerupgradable with furnace and vapour generation options.
Thermo Scientific* iCE 3400 Atomic Absorption Spectrometer features a dedicated furnace with the highest flexibility of Zeeman and Deuterium background correction.
Thermo Scientific* iCE* 3500 Atomic Absorption Spectrometer is a high performance, dual flame/furnace atomizer, double-beam Atomic Absorption Spectrometer.
Thermo Scientific* SOLAARsecurity Software is an optional upgraded software package to assist in compliance with FDA 21CFR Part 11 and GLP.
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I have made a number of purchases over the last several months,and I must say I am extremely well pleased with the quality of both your products and support. Delivery is fast and efficent,prices are excellent,and service/support is beyond first rate. I give you an A++ rating in all catagories. When I need anything electronic related, I will be sure to look here first.
- Carl B. (Shelbyville, TN)Great place to get what you need. Only site I could find what I needed. It was sent very fast and was exactly what I needed. Thanks Tech
- Doug L. (Van Nuys, Ca)Your satisfaction is 100% guaranteed
All products shown are in stock and carry a warranty – so you can buy with confidence! The quantity listed is all we have in stock... so don't delay, buy today! Join the thousands of satisfied customers we've been serving since 2001.
Contact Us
1610 Garden of the Gods Rd.
Colorado Springs, CO 80907
Sales: 1.866.880.1230
Operating Hours
Monday — Friday
Outlet Store:
9:00am to 6:00pm MT
Phone Inquiries:
8:00am to 6:00pm MT
Email Us
Sales/Product Questions
After Sales Support
Customer Service Request Form
Bill M. -
Apr 18th 2013