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So much is written about designing; motivation, materials and technique that I wanted to share my experience and the importance of organizing and keeping the workspace clean.
Being creative can be messy and that mess can lead to inactivity, slower creative pace and lack of focus. If you make jewelry (or any art) for money, you want to work efficiently to save yourself time and expenses. I compiled 10 important tips to keeping yourself organized, which will keep your mind clear and flowing and keep your sanity intact. *This post is specific to jewelry design but the basics can be used for any medium.
Besides being the former Director of Merchandising for a Isaac Mizrahi, Ltd which meant having to help organize the relationships between departments as well as product information, I am a professional artist and have been covering my every imaginable surface with materials since I could toddle around. I know how difficult it is to control yourself when you're in the throes of brilliance and your mind should be free to explore, not be worried about how neat your workstation is.
I've spent what seemed like an eternity searching frantically for a particular tool that was moved by Evil Gnomes. "I SWORE I just had it!" "Am I losing my mind?" Then by the time I got back to my project, some of my mojo was gone. I want to SAVE you from losing your mojo and meeting Evil Gnomes.
Ten FABULOUS tips for you:
- Try to set up specific workstations for specific tasks: beading, soldering (obviously for safety issues you will keep this area far removed from anything combustible), metal work. If you don't have the space for three workstations (I have five), get a large box with smaller organizers or a wheeling station and place your tools, materials for each technique inside. Easy access and it's all in one place.
- If an object doesn't belong in your workstation, put it away. You will free up space and you won't focus on a project you're not working on. * Keep all of your solutions, glue and tumbling supplies in a separate area (specifically up high where your young children can't reach). You will be less apt to spill or puncture bags filled with powder.
- When you have completed a project CLEAN UP before you begin the next one. Yes, you may have three projects started but only open the materials to one of them. Keep the other two projects sealed, out of the way and contained. Give your concentration to one-design-at-a-time. You will work smarter and be able to tackle technical problems easier.
- Keep the space BETWEEN your workstations open and clear. Imagine, you're done working your metal but you need to solder a connection – you turn to move to your soldering station and you trip over your stool or tri-pod. Not the best way to keep your "flow", plus you don't want to trip while carrying pointy tools.
- If your space is big enough for a bookshelf or shelves, store what you can up and out of the way. While I'm typing this I'm staring at five small boxes that found their way to the perimeter of my floor. Most are unnecessary and all should be moved.
- Store your materials in separate locations; stones, glass, silver, gold and so on. I don't mean to place them in different rooms but don't throw them all on shelves, haphazardly. I go so far as to categorize my stones by size and color on their own shelf; cools, warms, browns, greens, creams and then exotic (wood, teeth, shells). I use different sized clear containers and label them with stickers; stone name, size, purchase place, how many on strand, price, price-per-bead. Yes, it's an investment and work but when it's time to cost, you have all of your information on the container, plus it's easy to see what's inside when you store them upside-down on the shelf.
- Store your finished jewelry in your carrying pouch. What do you shlep with you to Trunk Shows or festivals? Store them in there. Organize it however you desire but keep them inside. Unless you need a particular piece as a sample to reproduce, don't keep it out. There is a greater chance of it being broken or the silver tarnishing.
- Cork boards, dry erase boards; use them. Course, I use my walls too – I have images and sketches and articles and pictures of my family pinned to every imaginable spot. Keep your design references in one area and your sketches in another. I like them visible to remind me what's next and stimulate my mind.
- Keep your photographic equipment separate. Again, it's best to keep your tri-pod, camera and tools together. If you have a separate room to shoot, kudos. I shoot outdoors so I keep my stuff in a corner, ready to gather up.
- CABLES! We live our days plugged in. I have cables for EVERYTHING; camera, computer, iPad, phone, printer… they were all jumbled in a $1 plastic container and it took me too long to untangle them so I placed them in their own sandwich bag. My goodness, I found that I have FIVE iPod cables! Now, I grab the bag I need; camera or web cam, use it, then roll it up and place it back in the bag. Saves me so much time and stress.
Set aside ten to fifteen minutes a day (or more often if you need) and begin to clear up and stabilize your work area. You will find that you are MUCH more productive and creative when your brain is free to create rather than search for missing items.
Organizing Resources:
The Organizer Store
Organize dot Com
CPS Containers and Packaging (for plastic containers)
*Did this article help you? When was the last time you organized your studio? What tools do you use to help you store your supplies and what other tips can you share with the Open Studio Art Community?Leave your comments below and SHARE this article by clicking the buttons below. Thanks!
You may also like:
Are you an Expert or an Experimenter? Your sales strategy depends on your answer
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Dear Creative – DON'T do-it-yourself!
For more helpful tips and art business information, dive into:
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Avery - Lightweight Flexi-View Presentation Binder 1" - Various Colors
A flexible round ring binder, with a stylish graphic border on cover that helps your work look great. See-through view pocket encourages you to customize both the outside and inside front cover for more professional presentations. Nonstick material prevents ink and toner transfer from printed pages. If your briefcase already weighs too much, choose the binder that's lightweight and easy-to-carry yet amazingly durable. The sky's the limit when you count this binder's potential uses: proposals, manuals, record-keeping, storage, data collection and more. PVC-free.
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Home › Community › About Us ›
About Us
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The Georgetown University Library is an agile organization that respects the heritage of the past while anticipating the requirements of the 21st century. By providing preeminent services, collections and spaces, the Library shapes the creation of knowledge, conserves culture for posterity, and transforms learning and research. Read more...


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More and more jobs deal in the virtual realm, and are done by people sitting down at desks at computers. Desk work can be made interesting in its own ways, but it's always fun to visit a company that's actually making physical stuff.
So for this episode of TechCrunch Cribs, we jetted over to New York City to check out the headquarters of Quirky, a startup founded back in 2009 with the aim of… → Read More
Android home gaming consoles are nearly arriving for the consumer market, but one at least needs a little more time in the oven to bake. It's the GameStick, the super portable USB-stick style device that plugs into an open HDMI port on your TV to turn it into an Android-powered gaming machine, and its release schedule is being pushed back another month until August, with a retail launch to follow… → Read More
The mobile wave has been cresting for several years now, so when a decade-old web company is only now debuting its first ever native mobile app, it's a little late to the game. The folks at TheLadders, which is launching its first iOS app this morning, understand that — but they are angling to make their "mobile last" strategy work in their favor in the long run.
It is indeed a beautiful app… → Read More
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The Erika Brown and Brady Clark rinks caputred the 2013 National Championships presented by Brooms Up Curling Supplies titles in Green Bay, Wis.
The Erika Brown and Brady Clark rinks caputred the 2013 National Championships presented by Brooms Up Curling Supplies titles in Green Bay, Wis.
Limited edition Team USA curling broom, manufactured by Balance Plus, autographed by the gold medal winners of the 2013 USA Curling National Championships -- the Erika Brown & Brady Clark rinks. Proceeds benefit the dual mission of the non-profit U.S. Curling Association to support our country's teams in pursuit of international excellence, and to develop the sport across the nation.
Tickets for the 2014 World Financial Group Continental Cup in Las Vegas are now on sale.
To order: http://www.curling.ca/2014continentalcup/ticket-information/
Want to win tickets? https://www.surveymonkey.com/s/2014Cup
Contest ends April 10.
The Miranda Solem and Korey Dropkin rinks captured the 2013 USA Curling Junior National Championships Feb. 2 at the Broomstones Curling Club in Wayland, Mass.
Women's champions: Miranda Solem, Vicky Persinger, Karlie Koenig, Chelsea Solem
Men's champions: Korey Dropkin, Tom Howell, Mark Fenner, Alex Fenson, Connor Hoge
Curling will be featured on NBC's "The Today Show" on Feb. 5 during the 8:30 a.m. ET time slot (time could change). 2006 Olympic bronze medalists Pete Fenson, Shawn Rojeski, & Joe Polo, along with 2011 national champion Ryan Brunt, will teach the show's four co-hosts the basics of curling during the show's week-long "Countdown to Sochi." Be sure to tune in!
Congratulations to the Margie Smith and Gert Messing rinks on winning the 2013 USA Curling Senior National Championships. They will represent the U.S. at the 2013 World Senior Championships April 13-20 in Fredericton, New Brunswick, Canada.


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Polling for 28 seats of NC Hills Autonomous Council underway in Assam
Voting is on for 28 seats of the North Cachar Hills Autonomous Council in Assam today. Over 1,21,000 voters are eligible to seal the political fate of 138 candidates. The Congress has fielded 28 candidates. The BJP has its candidates in ten constituencies. Nineteen former insurgent leaders are also in the poll fray. Meanwhile, security has been intensified across Dima Hasao District to ...
QB Mitchell decides on North Carolina State
FAYETTEVILLE, Ark. -; Former Arkansas quarterback Brandon Mitchell says he is transferring to North Carolina State to play his final ...
80-Year-Old North Carolina Educator Why I Got Arrested
Update: Barbara Parramore was taken into police custody Monday evening. Today I am participating in a non-violent and peaceful protest ...
Tornado slams school in Oklahoma City suburb
OKLAHOMA CITY - A monstrous tornado as much as a mile wide with winds up to 200 mph roared through the Oklahoma City suburbs Monday, flattening entire neighborhoods, setting buildings on fire and landing a direct blow on an elementary school. The weather service's preliminary classification of Monday afternoon's tornado was an EF-4 on the enhanced Fujita scale.There were no ...
Wake manager's budget $982M no tax hike
David Cooke wants to spend $982.8 million next year in a budget with no tax increase that funds growth in some county departments. Cooke gave his plan for fiscal 2014, which begins June 30, to the Wake commissioners on Monday. Under it, total spending would rise by $44 million, or about 4.7 percent, with education and public safety each getting $9 million of the increase. Some $17 million of ...
69.8°F Mostly Cloudy
Winds: Calm
Movie Review
A Fish Called Wanda [DVD]
A Fish Called Wanda is the greatest Ealing Studios comedy never made at Ealing Studios. Bought by the BBC in 1959, after which it shifted entirely to television production, Ealing had its golden age in the 1950s when it produced a string of pitch-perfect pitch-black ... ...
On Facebook
Trimeris buyer Synageva gets FDA nod
in 2011 merged with Lexington, Mass.-based Synageva BioPharma Corp. (Nasdaq: GEVA)? Synageva netted a win today - a "breakthrough therapy" designation from the FDA for the combined company's sebipase alfa, which is a treatment for a deadly pediatric disease. Called LAL, it's an inherited disorder that typically kills infants within the first six months of life. The ...
Warrant Raleigh man admitted involvement in political strategists stabbing death
Raleigh, N.C. - The man accused of fatally stabbing an up-and-coming political strategist and injuring her husband at their Raleigh home nearly a month ago was indicted Monday in the case - the same day a search warrant made public shows that he admitted to police his involvement in the crime.Jonathan Wayne Broyhill, 31, is charged with first-degree murder in the April 22 attack on Jamie Kirk ...
Cary's Ply Gem clears final hurdle
Cary-based Ply Gem Holdings, which wants to raise $345 million in an initial public offering, has received its final registration approval from ...
LexisNexis Cary division upgrades law firm software
The business data company LexisNexis is upgrading its Firm Manager software with a new tool to allow lawyers to share documents with each other and their clients via the Internet, managers said Monday. The new version of Firm Manager includes WatchDox, a file-sharing capability that's similar in concept to the popular Dropbox ...
Senior housing property sells for $31 million
A Georgia senior housing firm has bought the Manor Village at Preston apartment community in Morrisville for $31 million. The 166-unit community has been renamed as Preston Pointe. It was a unit of Rauls Convalescent Home Inc. of Macon, Ga., that purchased the property from Manor Village Life ...
Making headlines
Nothing will ever completely replace playing the game I love, however I feel like I'm starting a new adventure and I'm genuinely excited about what lies ahead. I'm fortunate to have been given many opportunities throughout my career and now I feel it's my time to give back.
David Beckham
The world's best known footballer was speaking after formally announcing his retirement.
Hotel Review
Hotel Galvez, Galveston, Texas
Coming off Highway 45, about an hour's drive and 50 miles south of Houston, and as we approached Galveston my ...
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Raleigh Times
Raleigh Times: Raleigh News Report in online newspaper formatThe Raleigh Times is essentially a local Raleigh newspaper, but with a national and international perspective, designed to provide readers with a one-stop shop for Raleigh, national US, regional, and world news coverage, weather and sports information, with live updates on breaking business stories, and what's happening in the financial markets.
The biggest advantage we have is that we are an online newspaper, which means we are constantly refreshing our stories as more and more information comes to hand. Often when a story breaks the initial details are sketchy.
We and our sources around the world work hard to gather more information, verify facts, and provide a perspective of the major stories. Expert opinion often accompanies our articles to better inform readers, and provide a more complete understanding
of the news we deliver.
Financial markets and business reports are regular features as we pin down what's happening, and constantly refresh stock market indice readings, dollar currency rates, and breaking business news reports. Our world sports coverage is a priority, as is our regional news.
We like to think if you're looking for breaking news out of Raleigh, North Carolina, the United States, or the world, you'll look for it first at the Raleigh Times.
- Voyage to Mars has its sceptics
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Move through Fantasy and Reality while watching Asian Drama!
of 2731
Description: "The story centers around a short 15-year-old boy named Ichimura Tetsunosuke who attempts to join the legendary samurai of Shinsengumi as part of his plan to avenge his murdered parents. However, he learns that he must become a demon to join this group." --Anime News Network


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The management of the Special Operations Unit charged Captain Fatal, the chief of the team, with undertaking an operation to take over the center of an international, weapons smuggling organisation.
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An invaluable artifact is kept behind a very strong security system, what would you do if you were a skilled thief? Sure you couldn't hold the urge to steal it right away. Then lets get started!
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Now you are able to travel along the world of winter fairy-tale! This game excels in it's diversity — from the form and features of the bat through to the large variety of tasks involved: you don't need to destroy all of the blocks, just open a way to the upper part of a screen to pass the level, a ...
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Jump, run and kick your enemies out of your way. Save Ted from enemies and help him to get to his home in this cute game.
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Play this funny game, try to reach the perfect ball control..
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Adventure of Ted is back with new exciting adventure. Evil Domba has captured Ted's kid. You have to help Ted rescue the little kid. Dodge all the creatures sent by Domba to stop Ted & teach Domba a lesson. Like us on Facebook: facebook.com/DreamGamez
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Jack Bauer's back to tackle an all-new threat! Step into his shoes for 24 adrenaline charged episodes of authentic '24' action! Go to the edge of disaster as you defuse bombs, fight helicopters, break codes & more in a suspense-packed 24 hours!
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The Polar bears have landed – for a Southern Invasion! Fend them off by hurtling courageous penguins at them in up to 60 new levels in this wacky sequel to Crazy Penguin Catapult! Complete missions perfectly for all new bonus levels & boss battles!
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Welcome to the new post-apocalyptic world full of mutant hoards and face the everyday survival struggle.
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The threat of global terrorism is at a new high, intelligence has led a group of the renowned Blade squadron of Eurofighters to a remote location with the sole duty of ending this war forever. Your job as squadron leader Blade 1 is to infiltrate the enemy bases and bring down the terrorists a ...
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Rolex Rankings No. 52
Rolex Rankings No. 36
This is the first year for the event.
Can Stacy Lewis defend her title?
This week is all about...Anna Nordqvist
Chella Choi answers 18 fun questions
During the week of the LPGA Championship Presented by Wegmans, Paige Mackenzie, Irene Cho, Mina Harigae, and Jean Bartholomew visited the Wegmans Organic Research farm.


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My girlfriend and I went on a "power walk" after work last night, which just so happened to lead us in the direction of Union Square. And since tax day was also pay day we didn't feel too bad splurging on a few spring items. I really love incorporating exercise with fashion; it's just so satisfying. And carrying shopping bags up hill is equally as tiring as if I had gone to the gym. I literally think I may be sore tomorrow. ;)
Oh PS: I am taking engagement photos for a friend this weekend. eeee!! So excited to see how / if they turn out. Please wish me luck. This is A LOT of pressure.
Happy Weekend!


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Did you know that over 34 million people were living with HIV at the end of 2010? Show your support for WORLD AIDS DAY this Thursday 1 December! Make a donation Virgin Unite is challenging YOU to show your support for World AIDS Day by engaging in a RED activity this Thursday 1 December! From wearing red to work (our cabin crew have a head start here!) to taking part in a red cake bake – the world is your oyster! Post your photos of your red activities to Virgin Unite's Facebook page or via twitter @virginunite to show your support. Take a moment to read all about the impact of the Bhubezi Community Healthcare Centre, an initiative supported by Virgin Unite and Ulusaba, Virgin Limited Edition's private game reserve. The Centre is a one-stop clinic for basic healthcare, TB and HIV/AIDS care, serving the local community in rural South Africa where most of the 500,000 population has limited access to health services and an estimated 20% are HIV positive. Meet the newest member of the Bhubezi Centre team, Richard Ubisi We caught up with Richard the newest member of the Bhubezi Community Healthcare Centre, team, to find out a bit more about him, his thoughts on the importance of World AIDS Day and the impact that Bhubezi is having on the local community… Introducing Richard… "My name is Richard, I am the Senior Manager for Clinical Services at the Bhubezi Clinic. I joined the Bhubezi Clinic on the 1st July 2011 having previously worked for the Matikwana Hospital as a General Manager and Marketing Manager there for the past 20 years. I have spent two decades of my working life in the health Industry, gaining Diplomas in: Human resources Management, Leadership Development, Financial Management as well as Hospital Management with the University Of Witwatersrand. My current role at Bhubezi is managing the staff and finances as well as helping with the smooth running of the clinic and the compliance and standard procedures for the programme." How important do you think World AIDS Day is? "World AIDS Day is on the 1st December every year and is the opportunity for people to unite in the fight against HIV. It is a day that brings together people from around the world to raise awareness about HIV/AIDS. People all over the world gather to remember the dead, pray for the living and draw strength for the journey. Some institutions do candle light memorial, and also encourage people to do a test to 'Know their Status'." What impact is the Bhubezi Clinic having in local community? "Bhubezi Clinic serves the community of approximately 70,0000 people. This is the only Autonomous Treatment Centre in Bushbuckridge providing holistic community health services, with the emphasis on integrated primary healthcare, chronic disease management, reproductive health and support services. Bhubezi also offers Community Health Awareness Mobilisation Prevention Programs (CHAMP), targets HIV/AIDS and TB by providing intervention in the areas where there the epidemic is at its worst. The clinic renders a holistic care i.e. screening of patients, Laboratory Services, X-Ray and Pharmacy. The clinic has uplifted the economy of this rural area by recruiting 51 employees from the local community." 29 Nov 2011 Virgin Unite
Bookmark & Share Help spread the word by sharing this page with others. Read all the news RSS feed Introducing the Virgin Unite Marathon Team 2012 12 December 2011 Richard and Christian Slater open creche. 12 December 2011 The One Brand donates over 100,000 condoms to Virgin Unite on World Aids Day 01 December 2011 'Screw Business as Usual' on bestseller list 30 November 2011 Did you know that over 34 million people were living with HIV at the end of 2010? Show your support for WORLD AIDS DAY this Thursday 1 December! 29 November 2011 9 Grammys, 8 multi-platinum albums ... and a heart of gold! 16 November 2011 Screw Business as Usual 15 November 2011 Campaign for an organ donation 'Opt Out' scheme in the UK 31 October 2011 Natalie Imbruglia on the seven billionth baby 28 October 2011


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$ 95.00
From our Red Fleece CollectionCargo shorts, made from a lightweight cotton. Antique zipper. Gingham pocketing. Two-hole fish-eye buttons. Two side-pockets with button closures. Two back pockets with flaps. One coin pocket. 10" inseam. Machine wash. Imported.
Unfortunately, we are unable to fulfill your requested quantity at this time. The remaining items will be shipped as soon as they are available.


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Intense Terahertz Pulses Cause DNA Damage but Also Induce DNA Repair
March 14, 2013 Terahertz radiation, a slice of the electromagnetic spectrum that occupies the middle ground between microwaves and infrared light, is rapidly finding important uses in medical diagnostics, security, ... > full story -
Nervous System
Stem Cells
Amyotrophic Lateral Sclerosis
Parkinson's Research
Disorders and Syndromes
Mutations in VCP Gene Implicated in a Number of Neurodegenerative Diseases
March 13, 2013 New research gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the ... > full story -
Novel Chemical That Controls Cell Behavior: First-in-Class Chemical Compound Might Control Metastases
March 13, 2013 It's the spread of the original cancer tumor that kills most people. That's why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. Scientist have found ... > full story -
Drug Treatment Corrects Autism Symptoms in Mouse Model
March 13, 2013 Autism results from abnormal cell communication. Testing a new theory, researchers have used a newly discovered function of an old drug to restore cell communications in a mouse model of autism, ... > full story -
Sex at Zero Gravity: Changes in Gravity Affect the Reproductive Process in Plants
March 13, 2013 Researchers found that changes in gravity affect the reproductive process in plants. Gravity modulates traffic on the intracellular "highways" that ensure the growth and functionality of ... > full story -
New Monoclonal Antibody Developed That Can Target Proteins Inside Cancer Cells
March 13, 2013 Scientists have created a unique monoclonal antibody that can effectively reach inside a cancer ... > full story -
Mechanism That Regulates Production of Energy-Burning Brown Fat Discovered
March 13, 2013 Scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings may lead to new ... > full story -
Molecule's Structure Reveals New Therapeutic Opportunities for Rare Diabetes
March 13, 2013 Researchers have determined the 3-D structure of a protein called HNF-4±. People with mature onset diabetes of the young (MODY1) have inherited mutations in the HNF-4± protein. This ... > full story -
Tapeworm DNA Contains Drug Weak Spots: Existing Drugs Could Be Effective in Treating This Damaging Parasite, the First Full Tapeworm Genomes Reveal
March 13, 2013 Tapeworms cause devastating disease around the world and new treatments are urgently needed. A new study describes possible targets on which currently licensed drugs could act, identified by genome ... > full story -
Immune Cells Cluster and Communicate 'Like Bees,' Researcher Says
March 13, 2013 The immune system's T cells, while coordinating responses to diseases and vaccines, act like honey bees sharing information about the best honey sources, according to a new ... > full story
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Información sobre riesgo, prevención, detección, síntomas, diagnosis, tratamiento y apoyo para el cáncer.
Información sobre el tratamiento del cáncer incluyendo quirúrgica, quimioterapia, radioterapia, estudios clínicos, terapia con protón, medicina complementaria avanzadas.
OncoLink se complace en ofrecer una amplia lista de lista completa de los agentes quimioterapéuticos más comúnmente usados??. Esta guía de referencia incluye información sobre la forma en que cada fármaco se administra, cómo funcionan, y los pacientes los efectos secundarios comunes pueden experimentar.
Maneras que los pacientes de cáncer y las personas que le cuidan puedan enfrentar el cáncer, los efectos secundarios, nutrición, cuestiones en general sobre el apoyo para el cáncer, duelo/decisiones sobre el termino de vida, y experiencias compartidas por sobrevivientes.
Tipos de Cancer / Cáncer de la Próstata / Recursos de NCI
National Cancer Institute
Ultima Vez Modificado: 29 de marzo del 2012
Note: Separate PDQ® summaries on Prostate Cancer Screening, Prostate Cancer Treatment, and Levels of Evidence for Cancer Screening and Prevention Studies are also available.
Benefits From Finasteride and Dutasteride Chemoprevention
Based on solid evidence, chemoprevention with finasteride and dutasteride reduces the incidence of prostate cancer, but the evidence is inadequate to determine whether chemoprevention with finasteride or dutasteride reduces mortality from prostate cancer.
Magnitude of Effect: Absolute reduction in incidence for more than 7 years with finasteride was 6% (24.4% with placebo and 18.4% with finasteride); relative risk reduction (RRR) for incidence was 24.8% (95% confidence interval [CI], 18.6%30.6%). There was no difference in the number of men dying from prostate cancer in the two groups, though the number of deaths was small.
In the dutasteride trial, using the restricted crude rate absolute risk reduction was 5.1% at 4 years, and RRR was 22.8% (95% CI, 15.2%29.8%, P < .001). There was no difference in prostate cancer or overall mortality, though the number of deaths was small and none were due to prostate cancer. The reduction in prostate cancer incidence occurred primarily in Gleason 5 to 6 cancers. 1 The reduction in incidence primarily in less aggressive cancers (i.e., Gleason 56) and not in more aggressive cancers (i.e., Gleason 710) raises the question of whether this reduction in incidence would lead to any reduction in mortality. This question is presently unanswered.
Harms From Finasteride and Dutasteride Chemoprevention
Men in the finasteride group had statistically significantly more erectile dysfunction, loss of libido, and gynecomastia than men in the placebo group. Men in the finasteride group had a statistically significant incidence of high-grade (Gleason sum 810) cancers during the study. 2 Whether this was a histological artifact or not is uncertain.
Magnitude of Effect: Statistically significant increases in the following outcomes were observed in the finasteride group (a greater fraction of men in the finasteride group [36.8%] temporarily discontinued treatment at some time during the study for reasons other than death or a diagnosis of prostate cancer than in the placebo group [28.9%]):
Overall, 4.3% of men in the dutasteride group compared with 2% of men in the placebo group discontinued the trial because of drug-related adverse events (P < .001).Men in the dutasteride group had a higher incidence of decreased libido, loss of libido, decreased semen volume, erectile dysfunction and gynecomastia than men in the placebo group. 1
Magnitude of Effect: Increases in the following outcomes were observed in the dutasteride group:
Other Prevention Interventions
The Selenium and Vitamin E Cancer Prevention Trial (SELECT [NCT00006392]) was a large randomized placebo-controlled trial of vitamin E and selenium. It showed no reduction in prostate cancer period prevalence, but an increased risk of prostate cancer with vitamin E alone. 3
Magnitude of Effect: Compared with the placebo group in which 529 men developed prostate cancer, there was a statistically significant increase in prostate cancer in the vitamin E group (620 cases) but not in the selenium plus vitamin E group (555 cases) or in the selenium group (575 cases). The magnitude of increase in prostate cancer risk with vitamin E alone was 17%.
Carcinoma of the prostate is the most common tumor in men in the United States, with an estimated 241,740 new cases and 28,170 deaths expected in 2012. 1 A wide range of estimates of the impact of the disease are notable. The disease is histologically evident in as many as 34% of men in their fifth decade and in up to 70% of men aged 80 years and older. 2 3 Prostate cancer will be diagnosed in almost one-fifth of U.S. men compared with about 3% of men who will be expected to die of the disease. 4 The estimated reduction in life expectancy of men who die of prostate cancer is approximately 9 years. 5
The extraordinarily high rate of clinically occult prostate cancer in the general population compared with the 20-fold lower likelihood of death from the disease indicates that many of these cancers have low biologic risk. Concordant with this observation are the many series of patients with lower-risk (i.e., Gleason 6 and some low-volume Gleason 7 tumors) prostate cancer managed by surveillance alone with high survival rates at 5 and 10 years of follow-up. 6 Data demonstrate, however, that with longer follow-up, higher-grade cancers are associated with a greater risk of prostate cancer death. 7 8
Because of marked variability in tumor differentiation from one microscopic field to another, many pathologists will report the range of differentiation among the malignant cells that are present in a biopsy using the Gleason grading system. This grading system includes five histologic patterns distinguished by the glandular architecture of the cancer. The architectural patterns are identified and assigned a grade from 1 to 5 with 1 being the most differentiated and 5 being the least differentiated. The sum of the grades of the predominant and next most prevalent will range from 2 (well-differentiated tumors) to 10 (undifferentiated tumors). 9 10 Systematic changes to the histological interpretation of biopsy specimens by anatomical pathologists have occurred during the prostate-specific antigen (PSA) screening era (i.e., since about 1985) in the United States. 11 This phenomenon, sometimes called grade inflation, is the apparent increase in the distribution of high-grade tumors in the population for a period of time but in the absence of a true biological or clinical change. It is possibly the result of an increasing tendency for pathologists to read tumor grade as more aggressive, resulting in a higher preponderance to treat these cancers aggressively. 12
Treatment options available for prostate cancer include radical prostatectomy, external-beam radiation therapy, brachytherapy, cryotherapy, focal ablation, androgen deprivation with luteinizing hormone-releasing hormone analogs and/or antiandrogens, intermittent androgen deprivation, cytotoxic agents, and active surveillance. Of all the means of management, only radical prostatectomy has been tested in a randomized clinical trial to assess survival benefit. In this study, prostatectomy was found to be superior to surveillance in men with localized prostate cancer in terms of reduced rates of metastases (relative hazard [RH] = 0.63; 95% confidence interval [CI], 0.410.96) and disease specific (RH = 0.5; 95% CI, 0.270.91) and overall mortalities. 13 The relative efficacy of radical prostatectomy to the other forms of treatment has not been adequately addressed. 14 Confounding issues in the treatment of prostate cancer include side effects with treatment, inability to predict the natural history of a given cancer, patient comorbidity that may affect an individual's likelihood of surviving long enough to be at risk for disease morbidity and mortality, and an increasing body of evidence suggesting that with careful PSA monitoring following treatment, a substantial fraction of patients may suffer disease recurrence . 15
Because of considerable uncertainty regarding the efficacy of treatment and the difficulty with selecting patients for whom there is a known risk of disease progression, opinion in the medical community is divided regarding screening for carcinoma of the prostate. While both digital rectal examination and PSA screening have demonstrated reasonable performance characteristics (sensitivity, specificity, and positive predictive value) for the early detection of prostate cancer, conflicting outcomes of randomized trials examining the impact of screening on mortality has led to some organizations to recommend for and others to recommend against screening. 16 17
The tremendous impact of prostate cancer on the U.S. population and the financial burden of the disease for both patients and society have led to an increased interest in primary disease prevention.
Risk Factors for Prostate Cancer Development
Back Up
Prostate cancer incidence escalates dramatically with increasing age. Although it is a very unusual disease in men younger than 50 years, rates increase exponentially thereafter. The registration rate by age cohort in England and Wales increased from eight per thousand population in men aged 50 to 56 years to 68 per thousand in men aged 60 to 64 years; 260 per thousand in men aged 70 to 74 years, and peaked at 406 per thousand in men aged 75 to 79 years. 1 In this same population, the death rate per thousand in 1992 in cohorts of men aged 50 to 54 years, 60 to 64 years, and 70 to 74 years was 4, 37, and 166, respectively. 1 At all ages, incidence of prostate cancer in blacks exceeds those of whites. 2
Approximately 15% of men with a diagnosis of prostate cancer will be found to have a first-degree male relative (e.g., brother, father) with prostate cancer, compared with approximately 8% of the U.S. population. 3 Approximately 9% of all prostate cancers may result from heritable susceptibility genes. 4 Several authors have completed segregation analyses, and though a single, rare autosomal gene has been suggested to cause cancer in some of these families, the burden of evidence suggests that the inheritance is considerably more complex. 5 6 7
The development of the prostate is dependent upon the secretion of dihydrotestosterone (DHT) by the fetal testis. Testosterone causes normal virilization of the Wolffian duct structures and internal genitalia and is acted upon by the enzyme 5-alpha-reductase (5AR) to form DHT. DHT has a 4-fold to 50-fold greater affinity for the androgen receptor than testosterone, and it is DHT that leads to normal prostatic development. Children born with abnormal 5AR (due to a change in a single base pair in exon 5 of the normal type II 5AR gene), are born with ambiguous genitalia (variously described as hypospadias with a blind-ending vagina to a small phallus) but masculinize at puberty because of the surge of testosterone production at that time. Clinical, imaging, and histologic studies of kindreds born with 5AR deficiency have demonstrated a small, pancake-appearing prostate with an undetectable prostate-specific antigen (PSA) level and no evidence of prostatic epithelium. 8 Long-term follow-up demonstrates that neither benign prostatic hyperplasia (BPH) nor prostate cancer develop.
Other evidence suggesting that the degree of cumulative exposure of the prostate to androgens is related to an increased risk of prostate cancer includes the following:
Ecological studies have found a correlation between serum levels of testosterone, especially DHT, and overall risk of prostate cancer among African American, white, and Japanese males. 14 15 16 However, evidence from prospective studies of the association between serum concentrations of sex hormones, including androgens and estrogens, does not support a direct link. 17 A collaborative analysis of 18 prospective studies, pooling prediagnostic measures on 3,886 men with incident prostate cancer and 6,438 control subjects, found no association between the risk of prostate cancer and serum concentrations of testosterone, calculated-free testosterone, dihydrotestosterone sulfate, androstenedione, androstanediol glucuronide, estradiol, or calculated-free estradiol. 17 A caution for interpreting the data is the unknown degree of correlation between serum levels and prostate tissue level. Androstanediol glucuronide may most closely reflect intraprostatic androgen activity, and this measure was not associated with the risk of prostate cancer. This lack of association affirms that risk stratification cannot be made on serum hormone concentrations.
The risk of developing and dying from prostate cancer is dramatically higher among blacks, is of intermediate levels among whites, and is lowest among native Japanese. 18 19 Conflicting data have been published regarding the etiology of these outcomes, but some evidence is available that access to health care may play a role in disease outcomes. 20
An interesting observation is that although the incidence of latent (occult, histologically evident) prostate cancer is similar throughout the world, clinical prostate cancer varies from country to country by as much as 20-fold. 21 Previous ecologic studies have demonstrated a direct relationship between a country's prostate cancer-specific mortality rate and average total calories from fat consumed by the country's population. 22 23 Studies of immigrants from Japan have demonstrated that native Japanese have the lowest risk of clinical prostate cancer, first generation Japanese-Americans have an intermediate risk, and subsequent generations have a risk comparable to the U.S. population. 24 25 Animal models of explanted human prostate cancer have demonstrated decreased tumor growth rates in animals who are fed a low-fat diet. 26 27 Evidence from many case-control studies has found an association between dietary fat and prostate cancer risk, 28 29 30 though studies have not uniformly reached this conclusion. 31 32 33 In a review of published studies of the relationship between dietary fat and prostate cancer risk, among descriptive studies, approximately half found an increased risk with increased dietary fat and half found no association. 34 Among case-control studies, about half of the studies found an increased risk with increasing dietary fat, animal fat, and saturated and monounsaturated fat intake while approximately half found no association. Only in studies of polyunsaturated fat intake were three studies reported of a significant negative association between prostate cancer and fat intake. Fat of animal origin seems to be associated with the highest risk. 20 35 In a series of 384 patients with prostate cancer, the risk of cancer progression to an advanced stage was greater in men with a high fat intake. 36 The announcement in 1996 that cancer mortality rates had fallen in the United States prompted the suggestion that this may be caused by decreases in dietary fat intake during the same time period. 37 38
Two studies were conducted within the Prostate Cancer Prevention Trial in which prospective nutritional information was collected and all subjects were recommended to undergo biopsy. Findings included that, among 9,559 subjects there was no association between any supplement or nutrient (including fat) and risk of prostate cancer overall but the risk of high-grade cancer was associated with high intake of polyunsaturated fats. In a subset of 1,658 cases and 1,803 controls, specific fatty acids were examined and docosahexaenoic acid was associated with risk of high-grade disease while trans-fatty acids (TFA) 18:1 and TFA 18:2 were inversely associated with risk of high-grade disease. These large scale studies suggest a complex relationship between nutrients such as fat and risk of prostate cancer. 39 40
The explanation for this possible association between prostate cancer and dietary fat is unknown. Several hypotheses have been advanced, including:
In a meta-analysis of ten cohort studies (eight from the United States and two from Europe), it was concluded that men with the highest intake of dairy products (relative risk [RR] = 1.11; 95% confidence interval [CI], 1.001.22; P = .04) and calcium (RR = 1.39; 95% CI, 1.091.77; P = .18) were more likely to develop prostate cancer than men with the lowest intake. The pooled RRs of advanced prostate cancer were 1.33 (95% CI, 1.001.78; P = .055) for the highest versus lowest intake categories of dairy products and 1.46 (95% CI, 0.653.25; P > .2) for the highest versus lowest intake categories of calcium. High intake of dairy products and calcium may be associated with an increased risk of prostate cancer although the increase may be small. 46
Regular multivitamin use has not been associated with the risk of early or localized prostate cancer. 47 However, in this large (295,344 men) study, there was a statistically significantly increased risk of advanced and fatal prostate cancer among men with excessive use of multivitamins.
The Aspirin/Folate Polyp Prevention Study, a placebo-controlled randomized trial of aspirin and folic acid supplementation for the chemoprevention of colorectal adenomas, was conducted between July 6, 1994, and December 31, 2006. In a secondary analysis, the authors addressed the effect of folic acid supplementation on the risk of prostate cancer. Participants were followed for up to 10.8 (median = 7.0, interquartile range = 6.07.8) years and asked periodically to report all illnesses and hospitalizations. 48 Supplementation with 1 mg of folic acid was associated with an increased risk of prostate cancer. However, dietary and plasma levels among nonmultivitamin users were inversely associated with risk. These findings highlight the potentially complex role of folate in prostate carcinogenesis. 48 49
Cadmium exposure is occupationally associated with nickel-cadmium batteries and cadmium recovery plant smelters and is associated with cigarette smoke. 50 The earliest studies of this agent documented an apparent association, but better-designed studies have failed to note an association. 51 52
Dioxin (2,3,7,8 tetrachlorodibenzo-p-dioxin or TCDD) is a contaminant of an herbicide used in Vietnam. This agent is similar to many components of herbicides used in farming. A review of the linkage between dioxin and prostate cancer risk by the National Academy of Sciences Institute of Medicine Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides, found only two articles on prostate cancer with sufficient numbers of cases and follow-up to allow analysis. 53 54 The analysis of all available data suggests that the association between dioxin exposure and prostate cancer is not conclusive. 55
Opportunities for Prevention
Back Up
The Prostate Cancer Prevention Trial (PCPT), a large randomized placebo-controlled trial of finasteride (an inhibitor of alpha-reductase), was performed in 18,882 men aged 55 years or older. At 7 years, the incidence of prostate cancer was 18.4% in the finasteride group versus 24.4% in the placebo group, a relative risk reduction (RRR) of 24.8% (95% confidence interval [CI], 18.6%30.6%; P < .001). The finasteride group had more patients with Gleason grade 7 to 10, but the clinical significance of Gleason scoring is uncertain in conditions of androgen deprivation. 1 High-grade cancers were noted in 6.4% of finasteride patients, compared with 5.1% of men receiving a placebo. The increase in high-grade tumors was seen within 1 year of finasteride exposure and did not increase during this time period. 2
Finasteride decreases the risk of prostate cancer but may also alter the detection of disease through effects on prostate-specific antigen (PSA), prostate digital rectal examination, and decreased prostate volume (24%), creating a detection bias. 3 Adjustment of PSA in men taking finasteride preserves the performance characteristics for cancer detection. 4
It is possible that finasteride induced the development of high-grade epithelial neoplasia, but this has not been demonstrated. 3 With a finasteride-induced development of high-grade prostate cancer, a gradual and progressive increase in the number of high-grade tumors would have been expected for more than 7 years, compared with placebo; however, this was not the case. The increase in high-grade tumors was seen within 1 year of finasteride exposure and did not increase during this time period. 2 An analysis of the PCPT data adjusted for the sources of detection bias found that finasteride reduced the incidence of Gleason 5 to 7 and Gleason 3 to 4 prostate cancer, but not Gleason 2 to 3 or Gleason 8 to 10. The reduction in the incidence of Gleason 7 (22%) was less than the reduction in the incidence of Gleason 5 (58%) and Gleason 6 (52%). 5 An analysis using different methodologies found an overall reduction of both low-grade (Gleason <6) and high-grade (Gleason >7) cancers. 6
The Reduction by Dutasteride of Prostate Cancer Events trial randomly assigned 8,231 men aged 50 to 75 years at higher risk of prostate cancer (i.e., PSA 2.510.0) with one recent negative prostate biopsy to dutasteride at 0.5 mg daily or to placebo. The primary endpoint was prostate cancer diagnosed by prostate biopsy at 2 years and 4 years after randomization. After 4 years, among the 6,729 men (82% of initial population) who had at least one prostate biopsy, 25.1% of the placebo group and 19.9% of the dutasteride group had been diagnosed with prostate cancer, a statistically significant difference (absolute risk reduction = 5.1% and RRR = 22.8% [95% CI, 15.2%29.8%]). The RRR in years 3 to 4 was similar to the RRR in years 1 to 2. The difference between the groups was entirely due to a reduction in prostate cancers with Gleason score 5 to 7. For years 3 to 4 there was a statistically significant increase in the dutasteride group compared with the placebo group in prostate cancers with Gleason score 8 to 10 (12 cancers in dutasteride group vs. 1 cancer in placebo group). 7
Overall, there was no statistically significant difference of high-grade tumors for Gleason 8 to 10 cancers in years 1 to 4 (29 vs. 19, 0.9 vs. 0.6%; P = .15). However, in a retrospective analysis there was a statistically significant difference between years 3 to 4. Because this is a small retrospective subgroup, the finding of an increase in Gleason 8 to 10 cancers is of uncertain validity. However, the finding of no reduction in these cancers is more significant. 7
There are several plausible explanations for the failure of finasteride or dutasteride to reduce the incidence of Gleason 8 to 10 cancers. Because of this uncertainty, the evidence is currently insufficient to determine the effect of prophylaxis with these drugs on prostate cancer mortality.
Agents that are used for hormonal therapy of existing prostate cancers would be unsuitable for prostate cancer chemoprevention because of the cost and wide variety of side effects including sexual dysfunction, osteoporosis, and vasomotor symptoms (hot flushes). 8 Newer antiandrogens may play a role as preventive agents in the future. 9
A Cochrane systematic review of all published studies of clinical outcome investigations of the prostate preventive effects of 5-alpha-reductase (5AR) inhibitors through 2010 that were at least one year in duration concluded that finasteride and dutasteride reduce the risk of being diagnosed with prostate among men who are screened regularly for prostate cancer. The review also concluded that mortality effects could not be assessed from these studies and that persistent use of these agents increased sexual and erectile dysfunction. The review was based on MEDLINE and Cochrane Collaboration Library computerized searches through June 2010 using Medical Subject Headings terms and text words finasteride,' dutasteride,' neoplasms,' azasteroids,' reductase inhibitors' and enzyme inhibitors' to identify randomized trials. Eight studies met the inclusion criteria. Only the Prostate Cancer Prevention Trial and the Reduction by Dutasteride of Prostate Cancer Events study were designed to assess the impact of 5AR inhibitors on prostate cancer period prevalence. Reviews of all eight studies concluded that compared with placebo, 5AR inhibitors resulted in 25% relative risk (RR) reduction in prostate cancers detected for cause' [RR = 0.75; 95% CI, 0.670.83 and 1.4% absolute risk reduction (3.5% vs. 4.9%)]. Six trials of 5AR inhibitors versus placebo assessed prostate cancers detected overall. Among these there was a 26% RR reduction favoring 5AR inhibitors [RR = 0.74; 95% CI, 0.551.00 and 2.9% absolute risk reduction (6.3% vs. 9.2%)]. There were reductions across age, race, and family history. One placebo-controlled trial of men considered at greater risk for prostate cancer based on age, elevated PSA and previous suspicion of prostate cancer leading to a prostate biopsy reported that dutasteride did not reduce prostate cancers detected for cause based on needle biopsy but did reduce risk of overall incident prostate cancer detected by biopsy by 23% [RR = 0.77; 95% CI, 0.70.85 and absolute risk reduction 16.1% vs. 20.8%]. There were reductions across age, family history of prostate cancer, PSA level, and prostate volume subgroups. The Cochrane review defined for-cause' cancers as:
Dietary Prevention With Fruit, Vegetables, and a Low-fat Diet
Results from studies of the association between dietary intake of fruits and vegetables and risk of prostate cancer are not consistent. A study evaluated 1,619 prostate cancer cases and 1,618 controls in a multicenter, multiethnic population. The study found that intake of legumes and yellow-orange and cruciferous vegetables was associated with a lower risk of prostate cancer. 11
The European Prospective Investigation into Cancer and Nutrition examined the association between fruit and vegetable intake and subsequent prostate cancer. After an average follow-up of 4.8 years, 1,104 men developed prostate cancer among the 130,544 male participants. No statistically significant associations were observed for fruit intake, vegetable intake, cruciferous vegetable intake, or the intake of fruits and vegetables combined. 12
One study of dietary intervention over a 4-year period with reduced fat and increased consumption of fruit, vegetables, and fiber had no impact on serum PSA levels. 13 It is unknown whether dietary modification through the use of a low-fat, plant-based diet will reduce prostate cancer risk. While this outcome is unknown, multiple additional benefits may be gleaned by such a diet, to include a lower risk of hyperlipidemia, better control of blood pressure, and a lower risk of cardiovascular diseaseall of which may merit adoption of such a diet.
While several agents, including alpha-tocopherol, selenium, lycopene, difluoromethylornithine, 14 15 16 17 18 vitamin D, 19 20 21 and isoflavonoids, 22 23 have shown potential in either cli
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If you like your rock n roll with some trash, some punk, some blues, some murder, more blood and a monster or two, then MOMMY S3Z NO! is for you.
"Horror movies and trashy rock 'n' roll - two of my greatest pleasures. So, when the Mommy Sez No album arrived boasting songs written for the movies 'Terror Overload : Tales From Satan's Truckstop', 'Klownboy : Circus Of Gore' and 'Stamgo! (Super Tromette Action Movie Go!)' and citing influences as cool as NYDolls, Thunders, Cooper and Dahl, the Stones, Pistols, I was as close as I could get to heaven.....if that place ever existed...... A terror trio so macabre that one of their members is called Evil, Mommy Sez No play "punk 'n' roll or horror rock or whatever you wanna call it" and 'Hotwaterburnbaby' is their second release since they formed in the Summer of 2007 in St. Paul, Minneapolis If you love Z-grade movie escapism, gutter dirty rock 'n' roll, Rue Morgue magazine and songs sung by drowned mass murderers, then this album is for you. C'mon, there has to be somebody else out there like me?!? Black heartedly recommended. " — Gaz E, UBER ROCK.COM RAZORCAKE.COM


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Because body image is sooo hot right now! But let's get down to nitty gritty….We are frequently asked to talk, lecture or exhibit, but just can't meet the demand. It seems everyone wants to chat about personal identity these days.
Who Are All Walks?
Fashion industry support
"It's very important that we question the parameters that define beauty. I'm thrilled to support the All Walks initiative." – Nick Knight
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The designers and the models we chose were crucial to the success of this project. "Individuality, uniqueness and character are all things that inspire me as a designer, All Walks celebrates this in an incredibly positive manner." Giles Deacon
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All Walks Beyond the Catwalk co-produced these awards for MP Jo Swinson. The night was a heady mix fun and serious commitment to change. Our thanks to Jo Swinson, Bare minerals and film maker Lee Jones who was there to record the excitement.


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Even a stopped clock is right twice a day, and once in a great while, conservatives must face the harrowing prospect of siding with liberals—even Barack Obama. Fortunately, the source of Obama's latest criticism, Bill Maher, makes the idea a little easier to swallow.
You may recall Frances Gallo, the Rhode Island superintendent who fired the [...]
Maher's Anti-Accountability Stance Is Too Much for Even Some Liberals to Stomach
March 16, 2010 By Calvin Freiburger 54780Leave a Commenthttp%3A%2F%2Ffrontpagemag.com%2F2010%2Fcalvin-freiburger%2Fmaher%25e2%2580%2599s-anti-accountability-stance-is-too-much-for-even-some-liberals-to-stomach%2FMaher%E2%80%99s+Anti-Accountability+Stance+Is+Too+Much+for+Even+Some+Liberals+to+Stomach2010-03-16+19%3A34%3A05Calvin+Freiburgerhttp%3A%2F%2Fwww.newsrealblog.com%2F%3Fp%3D41769
Filed Under: NewsReal Blog Tagged With: absolute authority, America, Barack Obama, Bill Maher, Central Falls, chewing gum, day, didn, doesn, Don, Education, education line, failure rate, Frances Gallo, John Legend, L.A. Times, local high school, Mrs. Crabtree, New York, parenting parents, President Obama, revenge fantasy, Rhode Island, Rhonda Robinson, school, siding, something fishy, staff, superintendent, system, Teacher


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We rarely go out to movies, but my husband really wanted to see see War Horse on Christmas Day. I had some trepidation, but read some reviews as I found the times at the theater in Harvard Square where he wanted to go.
I can recommend it, with a word of caution for those like me. I found it emotionally excruciating to watch and physically exhausting (from my sobbing thru much of the film). If you plan to see it and feel you might have a similar reaction, read several reviews first so you know what is going on and can be prepared. I suggest you go on a day when you have not been so busy that you are too tired, and that you leave time free afterwards to be quiet - such as just go home or go out for a quiet meal. We went out for dinner in a nearly empty restaurant (Jade on Mass Ave in Arlington - excellent!) and had a two hour drive to get home, so that helped. The movie will haunt you. But I must say, it has given me much to ponder and may change me in some positive ways.
I also found myself taking the movie personally on two fronts: first, my great uncle Cecil who did not make it home from WW1, and my grandfather a gentle soul who had to teach bayonet technique to his men. He alone survived a grenade to their fox hole. As a result he suffered "shell shock" (aka PTSD) and it really crushed him - my grandmother become the bread winner for the family as Grandpa slipped into alcoholism and resulting diabetes (he recovered from drinking and was an excellent grandfather to us kids, and taught us about Jesus). Second, my dad, a radio man in the US Army, stateside, went north from NC looking for my Uncle John (his younger brother and only sibling) the night before John's company shipped out for Normandy. He found him among hundreds of other GI's sleeping on the docks near their ship. Uncle John survived D Day. There is a scene with two German brothers that brought this to my mind. So maybe I had some extra emotional factors at play here that you won't have to deal with.
The ending is the only ending it could have and not make me a basket case.


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SEE NEXT PAGE: The Cobalt Craze: 6 Products We Love
SEE NEXT PAGE: The Cobalt Craze: 6 Products We Love
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(based on 8 reviews)
of respondents would recommend this to a friend.
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Reviewed by 8 customers
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Works great!
By djohns
from Canton, OH
Comments about 3M� Privacy Filters for LCD Monitors & Notebooks; Frameless 17:
Keeps patients from rubbernecking to see computer screen.
By LISA
from BRUNSWICK GA
About Me Quality Oriented
Good Deal; A Bit
By Mother Lynch
from Concord House
I got this for a good price. It gets very "staticy" so it attracts dust and pet-hair, which then sticks to it, resulting in it having to be cleaned more often than desired.But overall, it meets my satisfaction norms both price- and privacy-wise.Thanks Staples for a great buy!
(2 of 2 customers found this review helpful)
3M™ 17" LCD Privacy Filter by 3M
By Patti
from New Jersey
It is very easy to use, and I appreciate the privacy
(2 of 4 customers found this review helpful)
By Karen
from Perrysburg, OH
This worked great from the sides - the screen appeared to be off. However, with someone sitting behind you or walking up behind you it was as if there was no filter.
Effective, but expensive privacy guard
By ptk50
from NY/NY
About Me Value Oriented
no additional comments
(6 of 6 customers found this review helpful)
Good screen... that falls off.
By KKlosterman
from Columbus, Ohio
This screen is good, but it uses plastic adhesive strips to attach to the monitor. While this means the screen has a small "footprint", these strips eventually will fall off- leaving with either a useless privacy screen or using scotch tape.
(3 of 9 customers found this review helpful)
None of your business
By Fox
from Del Rey, CA
This product helps keep personnel personal information private.
Can't find what you need? Contact Us
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This Web site is intended only for use by U.S. residents.


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By: YNN Sports
The Lazers have made a laughingstock of the junior college lacrosse scene this season with their closest result being an 11-goal win over No. 2 Nassau, which is hosting this year's national tournament. Onondaga plays Genesee in the semifinals Saturday and the winner will play either Nassau or Essex in the championship game Sunday.


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Hey bud, yea, I remember you. You got ripped up by one of the stakes. ouch!! Yea, we are going back this year too. Have a situation though. bought (2) RV 50 amp spaces in ED1 but freinds backed out. Now I am on the edge of lossing both. ha ha ha. Thats why i hate flakes. If you know anyone who wants to buy a space or chip in to stay in our rv let me know. Thanks..oh, RV is going to be the biggest I can fit in 1 the space, and the other space is for the beer pong table and chairs to relax. Thanks for the pics too. later Nick
Junior Member


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Great points Dave! And, I'm a racist too... so tell me how it is after all the trillions we've sent to Africa and third-world countries around the world... they're still called third-world? Government can't fix social problems. It only makes them worse. When are we gonna learn?
So heres the thing, when someone tosses some name or derogatoory comment at you, bring it here to this forum, lets all work on it and find a way to turn it around to our advantage, then we can toss it right back into their faces.
(Can anyone else see the beauty and innocence in this?)
"What's little missy's name?" said Tom, at last, when he thought matters were ripe to push such an inquiry.
"Evangeline St. Clare," said the little one, "though papa and everybody else call me Eva. Now, what's your name?"
"My name's Tom; the little chil'en used to call me Uncle Tom, way back thar in Kentuck."
"Then I mean to call you Uncle Tom, because, you see, I like you," said Eva. "So, Uncle Tom, where are you going?"
"I don't know, Miss Eva." "Don't know?" said Eva.
"No, I am going to be sold to somebody. I don't know who."
"My papa can buy you," said Eva, quickly; "and if he buys you, you will have good times. I mean to ask him, this very day."
"Thank you, my little lady," said Tom.
I have a friend who is an experienced protester, actually hes a member of the other forum I frequent. Anyway, he said something that made a good deal of sense.
He said one of the things that get to people is to take what they throw at you, turn it around to your advantage and then throw it back at them.
That is where the idea for taking the word Racist and making it an acronym for something theyd be aghast about. We did the same thing when we were called A Mob.
So heres the thing, when someone tosses some name or derogatoory comment at you, bring it here to this forum, lets all work on it and find a way to turn it around to our advantage, then we can toss it right back into their faces. The other plus to that is once you turn it around to mean something that supports you and your stand, then it no longer has the power to hurt you because you dont think of it in the way they mean it, you think of it in the way you have changed it to mean.
like the police did with.... Pride Integrety and Guts...works every time!
I heard us called a Mobacracy last night...I kinda like it.
Not sure what one could do with that, but then.... it kinda stands on its own doesnt it?
There are a couple that are either too long to really work with (Like Astroturf) or are just too ingrained in bad vibes that it iws best to just flat out ignore the charge (like Nazi), but for the most part, most of what they throw at us we can turn to our advantage.


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Big 12
Big 12 Football: Who Was Impressive at the 2013 Senior Bowl
The 2013 Senior Bowl is in the books and some Big 12 players made some big impacts. So who impressed the scouts the most? Texas defensive end Alex Okafor had a very good showing, ...
Categories: Big 12


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Kohler K-4662-NY Dune Lustra Q2 Round Closed-Front Toilet Seat with Quick-Release and Quick Attach Hinges
Item #:
Compare Our Prices
Technical Specs
Installation Guide | |
Specification Sheet | |
Approved for Commercial Use | Yes |
Bowl Shape | Round |
Collection | Lustra, Q2 |
Country Of Origin | USA |
Length | 15.88 |
Material | Plastic |
Soft Close | No |
Theme | Commercial, Traditional / Classic |
Width | 14.19 |
Width (Inside) | 8.44 |
Product Features:
- Round-front toilet seat with lid - designed to complement a wide variety of round-front toilet designs
- This Lustra toilet seat blends with any bathroom décor
- The Q2 advantage seats feature innovative technology that makes it easy to install and clean
- Made of solid polypropylene and is resistant to staining, fading, chipping and peeling
- Seat is ergonomically contoured to provide maximum comfort to the user
- Complete with color-matched plastic hinges
Product Technologies / Benefits:
- Quick Attach: To get you fast on your way to enjoying your new toilet seat, the Quick-Attach Hardware from Kohler makes for fast and secure installation. Simply set the seat with the screws in pre-drilled installation holes, slip a wing-nut underneath and tighten from the top with a screw driver, it's that easy.
- Quick Release: This simple yet innovative technology from Kohler allows the seat to be unlatched from the toilet for easy removal and convenient cleaning with no tools required. Simply pop open the caps and gently pull the seat forward and you are ready for that detailed cleaning job that has been so difficult in the past.
- Height: 1" (measured from rim of toilet fixture to the highest point on the seat)
- Overall Length: 16-5/8" (measured from the back of the hinges to the front most part of the seat)
- Overall Width: 14-3/16" (measured from left most point to the right most point of the seat)
- Inside Length: 10-1/8" (measured from the back to the front of the inner opening of the seat)
- Inside Width: 8-7/16" (measured from the left edge to the right edge of the inner opening of the seat)
- Distance Required Between Installation Holes: 5-1/2"
- Toilet Seat Material: Sturdy plastic
- Secure mounting assembly while maintaining ease of installation
Additional Kohler Links
- View Manufacturer Warranty
- Shop All Kohler Products
- Shop All Kohler Lustra Collection Products
Our SKU: K-4662
This product is listed under the following manufacturer number(s):
Almond - K-4662-42*
Aspen Green - K-4662-96
Biscuit - K-4662-7
Black - K-4662-K4*
Cashmere - 4662-0
Chamois - 4662-0-Country Grey*
Country Grey - 4662-0-Desert Bloom*
Desert Bloom - K-4662-NY*
Dune - K-4662-W2*
Earthen White - 4662-0-French Vanilla*
French Vanilla - 4662-0-Harvest Gold*
Harvest Gold - 4662-0-Heron Blue*
Heron Blue - K-4662-95
Ice Grey - K-4662-55
Innocent Blush - 4662-0-Jersey Cream*
Jersey Cream - 4662-0-Merlot*
Merlot - K-4662-33
Mexican Sand - K-4662-52
Navy - 4662-0-Parchment*
Parchment - K-4662-53*
Raspberry Puree - K-4662-G9
Sandbar - K-4662-71
Seafoam Green - K-4662-6*
Skylight - K-4662-Y2
Sunlight - 4662-0*
Swiss Chocolate - K-4662-54*
Taupe - K-4662-NG*
Tea Green - 4662-0*
Swiss Chocolate - K-4662-56
Tender Grey - K-4662-58
Thunder Grey - K-4662-97
Timberline - K-4662-0
White - K-4662-45*
Wild Rose
*Denotes a finish or option that has been discontinued
4 Questions from the Community
Can I use a lid cover on this model?
Is this a replacement seat for the Rialto toilet?
Is this a replacement seat set for the Rialto toilet?
K-4662 ( White ), is it available, my seat came with the toilet and it is plain white, also does it come with plastic mounting screws or reuse the old screws
Product Reviews
Modern Round Closed Front Toilet Seat from Lustra Collection
Toilet seat comes up short
My "yes" answer to recommending it to a friend is only because there is no other choice at the moment for the Kohler toilet I have. The original toilet seat has been discontinued and this one is the current replacement. It is slightly too short for the toilet bowl shape.
November 7, 2010
Kohler K-4662 - Toilet Seats
Faucet Direct's product shipped 2 days earlier than originally scheduled. Items arrived intact without any damage or missing parts. Great service and overall a very simple and easy shopping experience. I would not hesitate to use them again and would recommend them to anyone looking for plumbing accessories, etc. Thanks again guys...
November 4, 2010
Sit On This!
Ten years ago we remodeled our guest bathroom and let our very young daughters pick out the theme of the bathroom. They chose Ariel the Little Mermaid. The entire bathroom and shower were decorated in that theme, including a cheap cushioned toilet seat with ocean life featured on the cover. My daughters loved that seat; my wife and I bit our lips. Last month we redid our bathroom and brought it into the new millennium. I didn't want to buy another cheap toilet seat from the "Big Box" stores so I talked my wife into spending a little extra money and bought this Kohler model. My wife and daughters are so glad I spent the extra amount on this seat. They love it. All of our guests think we purchased an entire new toilet--which we didn't--when they see the new seat. Very classy. Great purchase. I will definitely install an identical seat when I redo our Master Bathroom.
October 21, 2010
Great Replacement Seat
We replaced our original toilet seat with this one and it is a perfect fit. Instructions on how to remove the old seat and how to install this new one were user-friendly. It was easy to replace. We are very satisfied.
September 18, 2010
Solid, well-made product. Simple installation.
November 20, 2009
Nice and sturdy
I had purchased a similar seat at Home Depot and there is no comparison. The Home Depot Kohler seat looks similar but this one does not wobble and creek and it feels very sturdy. Everyone in the family loves it.
March 9, 2009
I cannot believe that I am writing a review of a toilet seat! What I am pleased with however is that I needed three replacement seats for Kohler toilets in my home. I got the replacement catalog numbers from the Kohler website. Kohler wanted $75. for each seat. Faucetdirect however charged $40. for each seat and it is a genuine Kohler, not an off-brand. The seats arrived when promised and installation was quaite simple.
July 29, 2008
1-8 of 8
The Bold Look of Kohler is more than a slogan, it is a testament to the sight and focus of the Kohler company since the late 1800's. Kohler designs its plumbing fixtures and accessories for longevity and with a focus on pleasing your senses. Kohler's attributes make its plumbing and accessories a clear choice of quality for generations to come.
Kohler Lustra Collection
With an ability to blend with any décor, the Kohler Lustra collection of toilet seats are east to install, as well as easy to clean.
Other Products In The Kohler Lustra Collection
Kohler K-4650
Lustra Elongated Open-Front Toilet Seat
$106.90$80.18(2) -
Kohler K-4652
Lustra Q2 Elongated Closed-Front Toilet Seat with Quick-Release and Quick-Attach Hinges
$106.90$80.18(8) -
Kohler K-4670-C
Lustra Elongated Open-Front Toilet Seat with Check Hinge
$39.05$29.29(1) -
Kohler K-4679-CA
Lustra Elongated Open-Front Toilet Seat with Anti-Microbial Agent and 1" Bumpers
$90.60$67.95 -
Kohler K-4660
Lustra Round Open-Front Toilet Seat
Warranty Info
Please call or use homepage to find the service center closest to your customer for all product warranty issues. "Power Equipment can not be returned to the vendor once it has been fueled or operated."


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I am doing R&S 2 Grammar: about 2/3 orally and 1/3 written. I like R&S, but I feel like I am missing out on narration, picture study and copywork. I am also doing MCP phonics (my dd has Teflon brain when it come to remembering phonograms), Cheerful Cursive, Apples & Pears Spelling and R&S 2nd readers (no workbooks).
I feel like our LA is very full, so I don't want to add CW Primer, but knowing that it has a phonics review, I was thinking that maybe I could do CW Primer instead of R&S and MCP Phonics. If I did this, would I be loosing out by dropping R&S Grammar? Is the grammar in CW comparable to R&S?
Is there any poetry or memory work in CW Primer?
If I did order Primer, should I order Fall or Winter. I would probably start the beginning of November.


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with video: Solar panel installation on University of Michigan property off Plymouth Road irks nearby residents
Joseph Tobianski | AnnArbor.com
Ward 2 Ann Arbor City Council member Jane Lumm sent a memo to U-M's director of community relations complaining about the lack of notice or community engagement prior to the installation.
Joseph Tobianski | AnnArbor.com
"This project is devoid of that very essential Ann Arbor 'ethos'," Lumm said in the December letter.
"The installation came as a complete surprise to me and to the many residents in [northeast] Ann Arbor who are now writing to express their shock and dismay at the... industrialization of Plymouth Road," Lumm wrote. "How can such a large project... suddenly take shape with zero heads-up or regard for community input?"
The panels are operated by DTE Energy on land owned by U-M. DTE began installing the solar array in the fall. DTE offered U-M an initial payment of $12,000 and will pay the school $12,000 a year to use the land, according to a university official.
The university receives $12,000 per year, which is dedicated toward landscape maintenance of the area. There was also a one time payment of $12,000 for the construction.
The assortment includes 1,800 panels and will generate enough energy to power about 100 homes, according to DTE estimates.
The panels span 2.4 acres of North Campus Research Complex land along Plymouth Road, near Nixon Road and Huron Parkway, acquired by U-M when it purchased the old Pfizer property in 2009.
"I happen to be a supporter of this type of project, but it looks hideous," said David Bizot, a northeast Ann Arbor resident and member of the Orchard Hills-Maplewood Homeowners Association. "Why didn't the university reach out and engage us? Looking longer term that's the bigger issue."
U-M President Mary Sue Coleman first announced U-M's plans to install solar panels during a sustainability address in September 2011. The panels are part of a $14 million initiative to enhance sustainability on the Ann Arbor campus.
Ryan J. Stanton | AnnArbor.com
In an interview, Jim Kosteva, the college's community relations director, said the solar panel array "is consistent with city goals and objectives on sustainability."
In a written response to Lumm, Kosteva — the college's community relations director — said that the panels didn't violate the northeast area planning vision, which highlighted the 2.4 acres for industrial and research use. When the planning report was first composed, the property was owned by Pfizer, a pharmaceutical company that operated in Ann Arbor.
The panels may be a head turner, but that's a good thing, Kosteva offered.
"As U-M continues to promote sustainability through various programs and initiatives, we also seek strategic opportunities to demonstrate our leadership," he wrote. "Choosing a prominent site for the solar panels and exposing the public to its location, especially within a research setting, reinforces the importance of embracing versus hiding."
Joseph Tobianski | AnnArbor.com
Later, he added: "There is no noise, no emissions, and no functional negative impact from solar arrays — they are simply new and different, and therefore may create an uncomfortable feeling for some as we collectively adjust to what may become a new future use of our landscape over time."
Kosteva said the project was considered an infrastructure improvement, not new construction, and thus wasn't announced to the nearby community, outside of media reports.
"What I will concede is that a specific location [of the panels] were not as clear as some would have preferred," he wrote.
To address aesthetic concerns, Kosteva said the university plans to add landscaping into the site. Kosteva plans to meet with Lumm and other concerned residents about the solar panels. Lumm said she will ask the university to remove some of the panels that are close to the road.
For affected residents, the panel field has the visual impact of a new building.
Kellie Woodhouse | AnnArbor.com
"U of M is sending the message that solar is industrial, in-your-face, and ugly and we had just better get used to it. I don't think that's going to win many converts," offered Bizot.
Yet more jarring than the aesthetic change, some residents say, is the university's lack of communication with residents.
"It's a structure. It's definitely a capital investment," said Sally Petersen, a Ward 2 council member. "I am up there almost evey day and, personally, I am not offended by them. But I would have liked to have known that they were coming and not to have been surprised by it. Visually, it would be good if there were some trees or something to block the view."
Petersen, first elected in November, said the solar panels "appeared overnight," frustrating residents, some of whom already have a list of grievances against the university, she said.
"I've been trying to build bridges between the university and the residents of Ann Arbor and this is making that more difficult," she said.
Peter Mooney, a northeast Ann Arbor resident and president of the Orchard Hills-Maplewood Homeowners Association, said he's hopeful the university will be more communicative in the future.
On Tuesday evening, the homeowner's association approved a resolution opposing the university's decision to go forward with the solar panel project in its current location without greater public input.
"In the future we'd like to be notified and have the chance to express our views," he said. "We would support getting some more input on any changes out there concerning the neighborhood and the major thoroughfare coming in."
Northeast Ann Arbor resident Greg Jagst puts it more bluntly: "I would like to see the university soften its approach with the community."
A view of the panels driving down Plymouth Road:


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[Solved] hex vs rgb
I was just wondering, is there any advantage in one over the other or it doesn't really matter cause both get rendered the same?I wrote an article on that very topic! http://joshnh.com/2011/09/29/hsla-are-you-using-it-here-is-why-i-think-you-should-be/Thanx JoshGot two questions.
How do I convert hex to hsl?
What those percentages attributes do?Here is the converter that I use: http://serennu.com/colour/hsltorgb.php
The percentage components of HSL are the Saturation and Lightness. 0% Saturation is no colour and 100% is full colour. 0% Lightness is black and 100% is white. So if you wanted red you would use hsl(0,50%,50%).


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7 bedroom detached house for sale The Poplars, 101 Hook Road, East Riding Yorkshire, DN14 5JT
A Unique Opportunity to purchase this truly elegant and beautifully designed early 20th century detached house, set within just over half an acre on the outskirts of the town with fine views to the front. This truly individual property boasts many fine and appealing features including a beautiful...
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6 bedroom detached house for sale Swinefleet Road, Goole, North Humberside
Spacious 6 bedroom detached famiy residence, standing in over one acre of grounds adjoining the River Ouse and erected in the early part of the 20th century, this fine residence enjoys a wealth of period features together with the ability to accommodate modern family living. The accommodation br...
5 bedroom mill for sale Shuffleton Mill Hook Road, Goole, DN14 5JB
SHUFFLETON MILL recently decorated throughout enjoys PANORAMIC VIEWS over the River Ouse to front and offers extensive living accommodation divided between the converted Period Mill and adjoining attached Dwelling. A VIEWING IS HIGHLY RECOMMENDED to appreciate the extent of this UNIQUE PROPERTY.
Marketed by Neville E. Townend, Goole.Telephone: 01405 468005 Local call rate
4 bedroom detached house for sale Russell Road, Goole, DN14
SIMPLY STUNNING!! A wonderful opportunity to acquire this UNIQUE INDIVIDUALLY DESIGNED and BEAUTIFULLY PRESENTED spacious four bedroom detached house which has been built by the current owners and is worthy of an internal inspection to appreciate the accommodation on offer. The property includes...
4 bedroom detached house for sale Haxby, 4 Airmyn Road, Goole
A period detached residence built in 1907 for ship owner and broker Herbert William Ezard. The four bedroom property retains a wealth of period features including original stained glass windows, decorative plaster mouldings and ornate tiled floors. Viewing is a must of this fine property.
Offers in Region of £295,000
4 bedroom detached house for sale 47 Westparkside, Goole
***MUST BE VIEWED*** Superb four bed detached residence in a highly regarded location. Double garage and generous private gardens. A viewing is highly recommended to appreciate the accommodation on offer together with the grounds and location.
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6 bedroom detached house for sale Danthorpe House, 31 Hook Road, Goole
*PART EXCHANGE CONSIDERED* An opportunity to acquire this individually designed, spacious, six bedroom family home standing in generously proportioned gardens and is situated in a prominent position of Hook Road, offering delightful riverside views.
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5 bedroom detached house for sale Stone View Carr Lane, Goole, DN14
A superb individual five bedroom detached house occupying a prominent corner plot location in a much favoured area of Goole. There are many highly commendable features including a double garage, an en-suite facility to the master bedroom, a family room, a maple effect fitted kitchen with built in...
6 bedroom detached house for sale Hudscroft Drive
HOOK The Landings is a small development of just nineteen stylish homes located off the High Street in Hook, on the west bank on the River Ouse. The small village has a pub, local store and sub post office, plus an excellent primary school. No chain
Marketed by haart, Doncaster.Telephone: 01302 484014 Local call rate
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3 bedroom detached house for sale 123 Hook Road, Goole
**STAMP DUTY PAID** This generously proportioned and well appointed home is located within gardens of approximately 1/4 acre, conveniently placed for all local amenities and access to the M62 at Junction 36.The property briefly comprises a large lounge, kichen, utility, dining room, conservatory,...