text:
American Dad: Volume 5 (US - DVD R1)
Gabe tries to convince you that unlike new Family Guy, this is a good show...
In the beginning American Dad was very much 'that other Seth MacFarlane show', but as the quality of Family Guy dipped, leading many fans to realize there wasn't much behind the show to begin with, American Dad surprisingly emerged as the more original, incendiary, and funny show. All shows go throw growing pains, but few shows see a sharp quality increase in their third and fourth seasons. However, I think the reason for American Dad's emergence as the superior MacFarlane show is actually pretty obvious when you look at the release dates of the first good episodes. The show, which was conceived as an excuse for staunch Liberal MacFarlane and his writing buddies to poke more pointed fun at post-9/11 Conservative America, started to click right around the time George W. Bush left office. With their easy target replaced with the relatively unfunny Obama administration (love him or hate him, Obama simply isn't the accidental comedic genius Bush was), the show was forced to adapt or die.
What makes the show better than Family Guy? Well, the lack of cut-away gags certainly doesn't hurt (it's not really a sit-com if it doesn't have any situation comedy, now is it?), but I think it's actually the characters that make the difference. American Dad's characters are no less arch than Family Guy's, but they've been given more room to grow on the whole. Family Guy is basically the Brain and Stewie show these days, and neither character works as a consistent lead. Roger the Alien is an obvious Stewie analogue, but he's kept a B-character more consistently. Roger's major character traits are also more bizarre and original. This volume of American Dad does threaten to over-expose Roger, but most of the Roger-centric episodes feel anomalous among the rest, and the exception rather than the rule. The writers have since widened their canvas to include their entire cast, though Francine is rarely given A-story material to work with minus Stan or Roger. The bigger and on-going problem, even now that the series has official been moved to the 'good' category, is that too many plotlines depend on Stan being generally a horrible person. This approach worked for The Simpsons, Family Guy and longer running Adult Swim favourites like Aqua Teen Hunger Force, but grew old, and is a symptomatic problem for modern sit-coms in general.
This volume five collection features fourteen episodes from the fourth season. There are some genuinely good episodes throughout the other seasons, and some of the developed character traits are lost in context, but overall I'd say this is a pretty solid place for viewers to start their American Dad experience. The overall collection is pretty consistent, but features a handful of standouts. 'Phantom of the Telethon' sets things off right with a healthy dose of darkly tinted political satire (Stan is holding a telethon because the CIA's 'torture budget' has been cut), and a good spot for all the major characters, especially Roger, who sees the whole event as an excuse to play Phantom of the Opera. 'Bar Mitzvah' is a fan, and (according to this collection's extras) writer favourite, and a generally great episode in terms of story structure, which apes Soderberg's Ocean's 11 remake, and all the films that inspired it. It's also the only episode in the collection to brush Stan almost entirely aside, including even a joke to point out the character's incidental presence in the story. 'Delorean Story-an' features a rare genuinely sweet father son story with relatively little subversion, and character elements that are specific to the series, rather than well-made replays of older episodes of The Simpsons. 'Weiner of Our Discontent' is, to date, the ultimate Roger-centric episode, and features one of the more satisfying A to B story wraparounds. 'Daddy Queerest' is the strongest episode overall, featuring poignant remarks on the politics of homosexuality, and a hilariously wrong-headed tirade against teen drinking from Roger. 'Jack's Back' isn't my favourite episode overall, but does feature the best dialogue exchange in the collection, when Haley beats Roger at his own game of dress-up and make believe.
American Dad has begun to air episodes in high definition with a widened 16x9 framing this year, but all previous seasons, including the episodes on this collection, were presented in 480i and 1.33:1 framing. It's quite likely the next volume release will be made available on Blu-ray, but until then fans have this perfectly adequate standard definition release to fill out their collections. Up-scaled by my Blu-ray player every episode features vibrant colours, blacks are solid, and elements are well separated. The show features a very simple visual style, with few shading elements, and basic, flat background elements, so detail really isn't an issue, though sharpness sometimes is. The whole print features minor, thin, white edge-enhancement, especially on the hard black lines. There is minor compression noise and blocking throughout, specifically on brighter background elements, and I caught quite a few interlacing effects. Objects and characters in quick, cross-screen motion are a bit 'fluttery', and there are combing artefacts on speedier mouth changeovers.
Each episode in this collection features a solid Dolby Digital 5.1 sound mix. The sound isn't much more expressive than a Dolby Surround mix in terms of stereo and surround elements, but the centred dialogue and LFE increase makes a real difference (though the throb of simple footstep effects is a bit overwhelming at times). Directional effects are mostly of the left and/or right to centre variety, but there are occasional rear element effects, like crowd noise, or big echo effects (the end of 'Daddy Queerest' features very effective stadium sound). The opening credit song and interlude music are pretty wide in scope, and just as theatrical as major motion picture scores. I should probably note that the dialogue is uncensored, which means there are plenty of naughty words that were cut from the original television airings.
Every episode in the collection features crew commentary. Participants vary from episode to episode and include creator/producers Matt Weitzman and Mike Barker, directors Brent Woods, Pam Cooke, Joe Daniello, Chris Bennet, Albert Colleros, Rodney Clouden, and Josue Cervantes, writers Brian Boyle, Nahnatchka Khan, Erik Sommers, Matt Fusfeld, and Laura McCreary, actress Wendy Schaal, and composer Walter Murphy, among others. Despite the constant cast change-up these tracks remain pretty consistent in tone. Everyone is dry, self-deprecating, and share a fun rapport with one another. Weitzman, being the one unifying element of all the tracks, acts as moderator as best he can. I can't say sitting through all of them didn't turn into a bit of a chore, but considering the sheer quantity of talking I can't say it's the worst I've dealt with. Disc two also features a 'Fact-Up' mode on 'Bar Mitzvah Hustle', which is a basic approximation of similar trivia tracks that appear on Blu-ray releases. The trivia is actually pretty informative, and covers more than the specific episode.
Disc four finishes the extras off with a collection of deleted/extended/alternate scenes, and the 'Power Hour Drinking Game'. There are twelve episodes that featured deleted scenes, and each episode is divided into its own section of brief chapters These are mostly brief dialogue gags, and mostly presented in the form of completed animation, with actual cast performances. The editors cut a lot of Klaus, apparently. The 'Power Hour Drinking Game' is a disappointment. Instead of an actual 'drinking game', one that requires the audience to pay attention to the on-screen information, this is a series of clips from the previous season. Each clip last approximately a minute, and is followed by an image of Roger drinking, with a prompt to take a drink. It's a nice clip collection, running approximately an hour, but a dumb 'game'.
American Dad keeps improving with time, and until it begins the same descent in quality that has brutalized Family Guy (which I fear is inevitable) I'm going to continue championing the show, and demand fans of animated comedy give it a proper shot. This volume five collection is a good place to start, and features some of the best episodes to date. Previous volume releases are not quite as satisfying, but are interesting if viewers are looking to watch an awkward series find its footing. I'm very excited for the next volume, which won't only feature my favourite episodes ('In Country…Club', 'Home Adrone', 'Rapture's Delight', 'May the Best Stan Win' and 'A Bully for Steve'), but should be released on Blu-ray disc. Until that time, this standard definition collection does fine, despite some interlacing artefacts. The commentary tracks are a big plus in the collection's favour, even if they don't match those of the Futurama or Venture Bros releases.
Review by Gabriel Powers
Existing Posts
i LOVE this show. i was so bummed/pissed when Fox took it off for the month(?) or 2 to air that "3 kids and a guy pretending to be their dad" show. i used to love Family Guy but it grates on my nerves SO much and too easily. there's really (IMO) not one NOT annoying character on the show. i DO love Stewie but he can't make up for the rest of the caustic characters. in American Dad, yes, Stan will very often be a total dick as will the awesome Roger, but at least we have Francine and Hayley and Klaus, etc to balance out the show! and what's so great is that this is ACTUALLY FUNNY! i used to love THE SIMPSONS as much but (i hate to say it) the simpsons hasn't made me laugh for a while now.
ahhh... the episode where Stan poops in the neighbors pool during a party... and tries to make it not seem so bad by trying to get Obama to poop in a public pool... holy c**p... so funny.
Erm, yes. It's just slightly lower in definition than 480i, and you need to buy a special TV to view it. It was kind of a waste of money because American Dad is the only show that uses it.
408i <- new format?
I agree with jp orestes. I've seen American Dad now and then, to me Family Guy is funnier. I'm getting sick of political bashing to some degree. The Bush stuff in Family Guy was funny. So was the Clinton c**p. But you can only do it so often. Thats what The Daily Show & Colbert Report are for. I praise both Family Guy & American Dad for being humorous in their own "subject matters". I do think Family Guy has a slight upper hand by having "Two" banned episodes by FOX to their resume. I saw "Partial Terms of Endearment" 2nd banned episode. BBC 3 aired it June 20, 2010, one of the best of Season 8 I thought. At the end of the day I hope both shows have success. I'll stick with Family Guy for the time being. Seth MacFarlane's a genius! keep up the good work. :-)
the episode where Roger joins the police academy has the biggest WTF moment at the end. i had missed its original airing and caught it online that same night. but finally seeing it on my 47inch tv...it was beautiful to see that "elbow move". the funniest part was Roger's reaction, literally the same thing i had said when i first saw it.
anyway yes this show has definately gotten better with time, like someone else said i cant say i prefer it over Family Guy as much as i just enjoy it on a different level.
anyway yes this show has definately gotten better with time, like someone else said i cant say i prefer it over Family Guy as much as i just enjoy it on a different level.
Definitely deserves a bigger fan-base as it is a very funny show. However, I still tend to enjoy Family Guy, although it is more hit and miss than a non-cancelled TV show should be.
I have really liked this show from the beginning but it wasn't until I bought the first DVD volume that I was hooked. I can't say I like it more than Family Guy but I love it for different reasons.
I wish more people I knew were into 'American Dad!' but out of all my friends it's only me and one other person who prefers this over 'Family Guy' by a longshot.
I wish more people I knew were into 'American Dad!' but out of all my friends it's only me and one other person who prefers this over 'Family Guy' by a longshot.
I cannot stand Family Guy so naturally wrote this show off since it seems to be much of the same, but after catching it one night on Foxtel I realised that this is damn fine comedy. I don't tend to rewatch much cartoon comedy, but this and Aqua Teen Hunger Force are a smarter form of comedy than your Family Guy dick joke style comedy.
This product has not been rated
Disc Details
Release Date: 15th June 2010
Discs: 3
Disc Type: Single side, dual layer
RCE: No
Video: NTSC
Aspect: 1.33:1
Anamorphic: No
Colour: Yes
Audio: Dolby Digital 5.1 English
Subtitles: English SDH, French, Spanish, Portuguese
Extras: Cast and Crew Commentaries, Bar Mitzvah Hustle Fact-Up Trivia, Deleted Scenes, The Power Hour Drinking Game
Easter Egg: No
Feature Details
Director: Various
Cast: Seth MacFarlane, Wendy Schaal, Scott Grimes, Rachael MacFarlane, Dee Bradley Baker
Genre: Animation and Comedy
Length: 306 minutes
7Review Guide
Follow our updates
New Editorials
Joe Lynch DVD | HD | BD David Hayter US - DVD R1 | BD RA SXSW Film 2013 - Part 1 US - DVD | HD | BD Will streaming kill physical media? DVD | HD | BD Gabe's 2012 Wrap-Up DVD | BD
Hot Articles
Star Wars: The Changes - Part One DVD | BD Star Wars: The Changes - Part Two DVD The Region 4 Ratings Logo Disaster DVD Star Wars: Top 20 Moments DVD Gabe's 2012 Wrap-Up DVD | BD
Latest Reviews
Perversion Story US - BD RA Fog, The UK - BD RB Batman: The Complete Animated Series US - BD RA Sorry to Bother You US - BD RA Torso US - BD RA
Most Talked About
A Simple Favor US - DVD R1 | BD RA All the Colors of the Dark US - DVD R1 | BD RA Reign of the Supermen US - DVD R1 | BD RA Kino Lorber Studio Classics January US - DVD R1 | BD RA Columbo Season 1 UK - BD RB


text:
Congress has become the butt of late-night comedians for waiting until the last minute to do any work, yet its procrastination involves something more than fecklessness: The issue over which it keeps stumbling not only separates its two parties into warring camps, but divides them internally.
WASHINGTON - Congress has become the butt of late-night comedians for waiting until the last minute to do any work, yet its procrastination involves something more than fecklessness: The issue over which it keeps stumbling not only separates its two parties into warring camps, but divides them internally.
At its core, the debate over the size of government and how to pay for it pits the interests of the huge baby boom generation, now mostly in their 50s and 60s, against the needs of the even larger cohort in their teens and 20s. With limited government money to spend, how much should go to paying medical bills for retirees versus subsidizing college loans, job training and health care for young families with children?
As they grapple with that, the party of small government increasingly relies on the votes of people dependent on entitlement spending. And the party that created the massive government programs for retirees has more and more become the political home of the young.
The part of the debate that ended Tuesday night mostly involved how limited the government's resources would be. Congress agreed to add about $620 billion to federal revenue over the next decade. But the vote locked in place the Bush-era tax cuts for everyone with incomes below $400,000 a year, a decision that denied the Treasury about $4 trillion over the same period.
That vote did not end the tax debate, but it did settle the biggest part of it. White House officials say that this spring, when the next budget deadline arrives, President Barack Obama will seek several hundred billion dollars more over the next 10 years. But even if he prevails over Republican opposition, the increment would be relatively small.
Increasingly, therefore, the coming fights over the budget will focus on the topic that both sides have shied away from: spending on retirees.
Both parties prefer to focus voters' attention elsewhere. Democrats like to blame the rise in the national debt on the George W. Bush-era tax cuts - 98 percent of which Congress just voted to renew - and the cost of the wars in Iraq and Afghanistan. Republicans like to point to Obama's economic stimulus efforts.
Each of those policies has contributed to the debt, but only to a limited degree. The real driver behind the government's long-term debt problem comes from the huge number of people entering retirement.
Over the last 40 years, the federal government has spent, on average, about 18.5 percent of the U.S gross domestic product - the overall output of the economy. At the current rate of increase, Social Security and Medicare alone would equal 16 percent of the economy by the time the number of retirees stops growing, about 25 years from now, the Congressional Budget Office projects. Most of the increase would come from the cost of health care.
Obama acknowledged that problem when he spoke Tuesday night.
"The aging population and the rising cost of health care makes Medicare the biggest contributor to our deficit," he said. "I believe we've got to find ways to reform that program without hurting seniors who count on it to survive."
That's a more straightforward acknowledgment of the problem than political figures typically offer. Liberal Democrats typically prefer to talk about taxes, not spending. Republican congressional leaders tend to do what House Speaker John A. Boehner, R-Ohio, did in his statement Tuesday night: avoid naming any specific programs and instead use euphemisms. He said he would push for "significant spending cuts and reforms to the entitlement programs that are driving our country deeper and deeper into debt."
The coy comments from both sides underscored the conflicts between their positions and their most potent supporters.
Democrats have long championed the government's social safety net. Medicare, passed under Lyndon B. Johnson, and Social Security, under Franklin D. Roosevelt, stand as two of the party's proudest policy achievements.
Yet Democrats' strongest support now comes from younger voters. Obama in particular has focused on the needs of that constituency, and he has shown more willingness than many in his party to consider trimming the cost of retirement programs. On Tuesday night, as he talked about the cost of Medicare, he repeated his call for government to spend more on "rebuilding our roads and bridges and providing investments in areas like education and job training" - the spending preferences of the young.
In December, during his negotiations with Boehner, Obama offered a shift in how the government calculates cost-of-living adjustments. That technical-sounding move would reduce the deficit by about $220 billion over a decade, in large part by slowing the growth of Social Security payments.
Even though the White House proposed ways to shield the poorest and oldest from the cut, the idea drew howls of protest from some liberal Democrats, a foretaste of the internal divisions likely to surface this spring.
But for a change, Democrats may be less divided than Republicans. The GOP's ideology of self-sufficiency and suspicion of big government programs has run directly up against the self-interest of its core constituency: voters in their 50s, 60s and 70s.
In November's presidential election, Mitt Romney won 56 percent of voters aged 65 and older. He took only 45 percent of those younger than 45, according to exit polling.
Given the conflict between ideology and the priorities of their key constituents, Republicans, not surprisingly, have had difficulty enunciating a clear policy. In the presidential campaign, the GOP backed the budget plan proposed by vice presidential nominee Rep. Paul D. Ryan, R-Wis., which aimed to reduce Medicare spending. Simultaneously, Romney denounced Obama for trying to trim the program and promised to spend $716 billion more than Obama on it.
Over the last month, the party has been similarly at odds with itself; as a result, Republican negotiators repeatedly declined to put forward a plan for restraining spending.
As the budget debate moves forward, the absence of a clear plan will be a weakness for Republicans that White House officials hope to exploit.
"There's difficulty in figuring out a position within the Republican conference," said Sarah Binder, a political science professor at George Washington University and senior fellow at the Brookings Institution. Party leaders have been willing to vote on general budget guidelines, she noted, but "not actual budget cuts, not actual allocations."

subset: commoncrawl


text:
You are here: Root > By Topic > DatabaseView the dependency graph for this library
cl-store is an asdf-installable portable library for serializing and deserializing Common Lisp objects to and from streams. It currently runs on SBCL, CMUCL, CLISP, ACL, OpenMCL and Lispworks.
|Web site
|Mailing list
|0.6 -
|OS compatibility
|ASDF installable
|Official Download
|Mirrored Download
|Source code repository
CL-STORE is a package written by Sean Ross for serializing and deserializing CL objects from streamsIt has been tested and works on
CL-STORE currently supports serialization of
Example: ;; Store a class and instance cl-user(1): (defclass foo () ((bar :accessor bar :initarg :bar))) cl-user(2): (cl-store:store (list (find-class 'foo) #'bar (make-instance 'foo :bar "bar")) "test.out") ;; Then restore them in a fresh lisp session cl-user(1): (let ((vals (cl-store:restore "test.out"))) (funcall (second vals) (third vals))) => "bar"
ECL | OpenMCL | Allegro Common Lisp | LispWorks | CLISP | CMUCL | SBCL
cl-wdim | The Sewer Massacre | BDB - Berkeley DB CFFI bindings
Database | MIT | Utilities | Object-Oriented | Data structures
You must be logged to add a note
You must be logged to add a comment


text:
|Photo Albums
|Registered Visitors
|Social Groups
|Today's Posts
|Mark Forums Read
|Elsmar Cove Forums FAQ
|Here are a number of 'How To's' (FAQ - Frequently Asked Questions) on how to do things in the Elsmar Cove Forums. There is also a 'How To' forum with more detailed 'How To' threads. See: Instructions --> How To Use the Forum Software - You can ask questions there as well.
|Board FAQ
|Here you can find answers to questions about how the board works. Use the links below or the search box above to find your way around.
|Blog FAQ - Personal Blogs
|The Blog system gives you your own personal Blog space at The Elsmar Cove Business Systems and Standards Discussion Forums. You must have at least 20 posts in the forum before you can have your own personal blog, to be able to create your own entries and to control who may view them.


text:
I disagree with J. Blair Reeves' attack on Ayn Rand's objectivism as "madness," which is an epithet, not an argument [Letters, "I thought Ayn Rand died," April 7]. I also disagree with the statement of Evan Williams, trying to defend her ["Sacrifice is Voluntary," April 14], that sacrifice is voluntary or his idea that Rand should be put in with the libertarians.
I have been reading Rand since 1968, and no one should take anybody else's word about her philosophy. Read her for yourself. I advise starting with the novels instead of the non-fiction, unless you don't like a good story.
Jack CrawfordSilver Spring, MD


text:
Watford - Aston Villa, Live commentary & Livescore!
The live commentary will start soon after the starting whistle
Where to watch the game live?
Sky Sports TV
We've found some websites that broadcast this event on Sky Sports. Click here for watching Watford - Aston Villa on Sky Sports!
FOX Sports Live TV
Fox Sports is broadcasting this event live online in: Australia, Italy and Netherlands. Click here to watch Watford - Aston Villa on FOX Sports TV!


text:
Box Appetit - Lunchbox by Black + Blum
A revolutionary lunch box!
Like, comment or show your love and get 5% discount!
Your discount will be applied.
DescriptionOur friends over at Black + Blum in the UK designed this revolutionary lunch box.
It's more like a ceramic bowl than your standard food container and with better functionality. The 'glass like' lid locks to the body for a water tight seal and has an ingenious sauce dipping area (good for sushi lovers). A sauce pot is ideal for salad dressing (or ketchup), so you can dress your salad just before you eat it. An inner dish allows you to split different foods so you can microwave a hot dish, but keep other foods cold.
The box includes a fork / knife for easy one handed eating.
Material: Polypropylene and Copolyester (BPA free) - microwave and dishwasher safe.
Dimensions: 19x19x5.5 cm and 880ml / 30 fl oz
|Daniel Black & Martin Blum
|Black + Blum
|Great Britain
Comments (0)
No review available for this item.
Was unsere Kunden über dieses Produkt sagen:
you may also like
Register & activate your discount!
Everyday fresh design from Charles & Marie
- Yes please - Keep me in the loop about the latest trend in design and Charles & Marie's special offers.
- Send me the daily 'Soupe du Jour' newsletter so that I'm always ahead of the latest trend and don't miss your daily special offer.
15.00 €*


text:
Wish List (0)
My Account
Shopping Basket
Welcome visitor you can
create an account
Horse Trailer Accessories
Trailer Care
Trailer Care
Trailer Care
Refine Search
Cleansing Tools
Shampoo's & Polish
Sprays & Greases
Tyre Pumps
Product Range
Customer Service
Shopping Help
Horse Trailer Accessories
Towing Vehicle Accessories
Horse & Rider Acessories
Special Offers
About Us
Delivery & Returns
Privacy Policy & Cookies
Terms & Conditions
View Basket
My Account
Contact Us
Website content copyright © 2016 Horse Trailer Shop. All Rights Reserved.
Web Design
Horse Trailer Shop sell a large selection of quality
horse trailer parts
that can be purchased online. Our
horse trailer spare parts
are organised in to categories and sub categories to make it easy to find exactly what you are looking for. We stock a dedicated range of
Ifor Williams horse trailer spare parts
that are designed to fit Ifor Williams trailers. If you have any questions about our
Ifor Williams horse trailer parts
or our collection of
parts for horse trailers
please call us on 01305 269393


text:
Needing more rounds, Rory McIlroy decides to play Texas Open
SAN ANTONIO – Rory McIlroy is going to play another week in Texas to get ready for the Masters.
McIlroy decided Friday to play next week in the Texas Open, wanting one more tournament to try to find his form ahead of the first major of the year. The two-time major champion has only played five tournaments this year, making just two cuts.
He has completed only 10 rounds through Friday of the Houston Open.
McIlroy lost his No. 1 ranking last week to Tiger Woods, who won at Bay Hill. Even so, it gives the Texas Open its biggest name in more than a decade.
It's a big change from last year, when McIlroy took off three weeks before the Masters.


text:
General Store hosts free clothes give-away
The General Store on Witte will hold a clothing giveaway from 10 a.m. to 5 p.m. Friday, May 31, at 104 N. Witte St.Sizes range from children's to adult, according to owner Darleen Seaman.Seaman said she started accepting donations for the giveaway last week and "we got an enormous amount — which is what we wanted." She will accept additional donations beginning Wednesday, she said.Poteau Main Street Matters is providing tables for the event.A similar giveaway in April "was an amazing blessing," Seaman said."We had people say they found clothes to job hunt and wear to church," she said."We started out with nine tables full and had only one little bag left. It's a great way to recycle good, useable things," she said.Refreshments also will be available.For more information or to donate items, call the store at (918) 208-7685.


text:
Wapak cruises to 5-0 win over Lima Senior
From staff reports
The Wapakoneta Redskins did not lose a game Friday in their 5-0 win Friday over the Lima Senior Spartans in a non-league varsity girls tennis match at the Collett Street Courts in Lima.
The win was Wapak's second by a 5-0 score and moved the team's record to 2-0 this season.
Recording wins in singles action Friday were Kaitlin Snider (first), Kiersten Wellons (second) and Chelsea Myers (third).
Appearing in their first matches of the season, Carly Buzzard and Mackenzie Haverman were Wapak's victorious first singles team. The duo was slated to play Tuesday against Bellefontaine but their match was forfeited.
Also making their first appearances this season, Wapak freshmen Madison Watt and Cassidy Hayes earned win at second singles Friday.
The Redskins will visit Kenton in their Western Buckeye League opener at 4:30 p.m. Monday.
Follow high school tennis coverage from the Wapakoneta Daily News on Twitter using the hashtag #wdnTEN


text:
Thanks to werner, that battle bots thing is cool and easy to use and its easy to get at http://robocode.alphaworks.ibm.com/home/home.html
All the news that's fit to assimilate[ Home | Blogs | Events | Robots | Humans | Projects | Podcasts | About | Account ]
Thanks to werner, that battle bots thing is cool and easy to use and its easy to get at http://robocode.alphaworks.ibm.com/home/home.html
Not much new. Untill I get some more money.
Thanks to all that cirtified me. Now that i am an aprentice i can put in my projets (when i finally finish them).
Im waiting for my microcontroller to come in so i can get started on "the hand".
Plese some one cirtify me to an aprentice so I can put my robots on.
Well Ive started on the design of the finger, it's pretty basic: When you bend your finger some parts get closer together and some further apart. So if i were to put two wires apart from eachouther but when the finger part comes together they connect. This will activate a motor witch will move the robot's finger. Later when I lurn Basic I'll make it with sensors and more acurate. Then I will turn it into a hand so I can get something that is far away without moving much. If you have any good informaition or you know were on the net I can lurn Basic plese Email me at: firstname.lastname@example.com Thanks for reading this.
I want to make robot hand that will respond to my movements. But I think I'll start with a finger and then move along to the hand.
I made my first robot. It's a BEAM robot bug thing. Thanks to http://members.tripod.com/robomaniac_2001 for giving me the design. Now i am going to make a more helpful robot to use around the house.
2012 Top 10 Robot Christmas Gift Ideas
DARPA Robotics Challenge Kick Off
2012 ASABE Robot Contest Photos
Interview with David L. Heiserman
David Anderson on Subsumption Robots
Review: Apocalyptic AI by Robert M. Geraci
Raspberry Pi Interview with Eben Upton
2012 VEX Robotics World Championship
Giant Dallas Robot Cited as Best Public Art
There's More Than One Way to Skin a Robot
Day of the Androids at Hanson Robotics


text:
Director of the Center for Economic Freedom at FreedomWorks; Editor of RealClearMarkets; Senior Economic Advisor to Toreador Research & Trading; Author of Popular Economics and Who Needs the Fed?
Bio Info
As the world becomes smaller and the marketplace larger, John Tamny challenges collected, conventional wisdom, making the money people and the rest of us think.
Founding Editor, Fast Company and Best-Selling Author, Mavericks at Work, Practically Radical and Simply Brilliant
Types: Author, Entrepreneur, Futurist, Male, University Professor
Bio Info
Bill Taylor has a passion for the ideas and practices that are reshaping how organizations compete, innovate and win. As co-founder and founding editor of Fast Company, he shook up the business-magazine world and the world of business. His new book shows how to unleash breakthrough creativity and cutting-edge performance in even the most traditional fields.
Advertising Hall of Famer, Branding Expert, Entrepreneur and Best-Selling Author
Types: Author, Entrepreneur, Female, Top Executives
Bio Info
Linda Kaplan Thaler helps audiences around the globe tap into their incredible power of grit, perseverance and determination to succeed at the highest levels in their careers and professions, and in their personal lives. She also speaks extensively about how the "power of nice" is the most powerful leadership tool in business today, as well as how to make any environment a hotbed of creativity and innovation.
One of the World's Most Famous Comedy Troupes
Types: Group / Couple
Bio Info
From the world famous The Second City Theater that gave us such famous comedic actors as Dan Ackroyd, John Belushi, Tina Fey, Amy Poehler, Steve Carel, and Steven Colbert comes a proven and innovative training methodology that builds the skills necessary to make companies successful.
World Champion Quarterback, Broadcaster and Entrepreneur
Types: Athlete, Author, Entrepreneur, Football Player, Male, Sports Broadcaster
Bio Info
Losing his successful football career at 35 to a serious injury, Joe Theismann learned firsthand how to think, analyze and reinvent in the face of adversity and change.
Senior Executive Coach, Successful Business Leader and New York Times Best-Selling Author
Types: Author, Entrepreneur, Male, University Professor
Bio Info
Called one of "America's top investors with the 'Midas' touch" by Forbes, Mark Thompson helps high achievers drive growth, change and engagement to take their organizations to the next level of success.
Founder, Ethos Water, Founder and CEO, Liberty United and Fonderie 47 and Recognized Social Entrepreneur
Types: Entrepreneur, Male
Bio Info
A recognized enterprising pioneer who has used his keen entrepreneurial skills to build several businesses founded on advancing a social mission, Peter Thum is a humanitarian who shows that business can do good while doing well.
Bio Info
The most respected manager in baseball today, Joe Torre shares his individual and organizational secrets of success, sacrifice, communication, trust and dealing with adversity.
National Security Analyst, CBS News; Assistant to the President for Homeland Security and Counterterrorism (2004-2008)
Types: Female
Bio Info
With over 20 years of world crisis experience, Frances Townsend identifies the danger spots around the world and analyzes their potential impact on you and your organization.


text:
If you want to have beautiful skin, then it is very likely that you will do most anything you need to in order to improve the look of your skin. There are many products that are available today to purchase, but one of the most popular ingredients in many of them is AHA or Alpha Hydroxy Acid.
Most people have heard of this ingredient by now because it is often advertised as being good for ones skin and really making a difference in the appearance of the skin as well. It works by exfoliating the dead skin cells and allows the younger more youthful skin to appear underneath which looks much younger and healthier.
AHA has long been used to help the appearance and texture of the skin. It is very popular to help the skin look younger and reduce fine lines as well as other things that cause premature aging.
ZENMED offers this ingredient in our AHA / BHA Complex (Beta Hydroxy Acid) and if you want to find one to give you the most benefits you may want to consider looking at their huge line to allow you to do so. You have many to choose from and you can really make a difference in the way you skin looks and feels when you use AHA.
Many wrinkles can be reduced when an ingredient such as AHA is used on a daily basis. This is a huge part of the allure and popularity of this particular ingredient and it can aid you in having much younger looking skin when you too use it regularly. You may want to check out all of ZENMED skin care products to find the one that will work best for you and you then can get the results you wish to have.


text:
Style # 197656
With a flirty high-low skirt and citrus-hued stripes, this bebe dress is sure to be an effortlessly-chic warm-weather staple. Try it with a pair of wedge sandals and a crossbody bag.
- 100% micromodal
- Center back to hem: 35" (89 cm)
- Machine wash according to care label
- Imported
- Model is 5'9" and is wearing a US size S
High Low Stripe Tank Dress is rated out of 5 by 3.
Rated 5 out of 5 by Lola12 from Love this dress! Very cute summer dress that is also comfortable. Medium was perfect for me
Date published: 2013-08-02
Rated 4 out of 5 by sbrya28 from Lovely striped dress! I purchased this in a size Small; what struck me right away was the mingling of colors and how they all compliment each other. Bebe is making more hi-lo dresses nowadays, which is a bit much, but I do understand that the look is still in style. That means for me, being 5'3", that I will probably have to have the lo part hemmed, like with other hi-lo dresses. But in this case, it is worth it; everything else fits true to size. The chest is not too tight and not see-through, and the material is very comfortable and light. I will wear this with a denim jacket and tan wedges for a casual dressy style!
Date published: 2013-06-11
Rated 5 out of 5 by hot hot hot from I Love it!!! "I have been a loyal customer for years and it's dresses like these that keep me coming back for more. Super cute, super comfy, absolutely great for the summer. I just love your style..THANKS BEBE!!!"
Date published: 2012-05-06


text:
One Pair - Pawnee Universal Black Stalk LED Turn Signals
Amber LED
Universal LED Stalk Turn Signals for OEM indicator replacement. Compact stem size for front or rear mounted sidemarkers. Blinkers offer a narrow oval shaped lens, two unique illuminated amber windows on the back, and rubber flexible stud shafts able to bend up to 90 Degrees and reduce vibrations. Markers require little to no fairing modification, depending on your application, but you may need to splice the wiring.
Dimensions: Multiple, please see photo(s)
Housing: Black High Impact PVC Plastic, 24 Amber LED's on Front, 5 LED's on Back
Stalk: Black High Impact PVC Plastic, Steel Mounting Stud and Nut
Wiring: Two Wire, 12 Volt Systems
Install Motorcycle Turn Signal Instructions
Fitment Information: This is a Universal Turn Signal Light; therefore, it has unlimited uses and mounting possibilities. This includes: Sportbikes, Cruisers, Scooters, ATV, Quad, UTV, MX, Dirt Bike, Enduro, Dual Sport, Golf Carts, and even Snowmobiles.
NOTE 1: This is an LED Turn Signal and can increase the Flash Rate of your turn signals. Flash Controllers (Resistors or LED Relays) are not required, but are recommended if you want to correct the hyper flashing. Resistors and Relays are available separately here.
NOTE 2: These Turn Signals are pictured installed with our Turn Signal Adaptors; the Adapters are an optional purchase and are not included.
LED Relay Flash Controller - Suzuki - 7-Pin
Regular Price: $49.95
Special Price: $22.95
LED Relay Flash Controller - Honda, Kawasaki, Yamaha
Regular Price: $19.95
Special Price: $14.95


text:
Is your 5-year-old ready to know about the birds and the bees? In a move to meet state and national guidelines and to curtail climbing rates of sexually transmitted disease, the Chicago Board of Education voted to expand sex education in public schools, reports ABC News.
As part of the new program, kindergarteners through third graders will learn the basics of anatomy and reproduction, as well as good and bad touch. Fourth graders will be educated on puberty and HIV. In fifth grade, topics will include reproduction, birth control, abstinence and the transmission of STDs. Sexual orientation and gender identity will also be explored.
"From a public-health standpoint, it's an absolute imperative," Dr. Bechara Choucair, the commissioner of the Chicago Department of Public Health, told DNA Info Chicago. "It can no longer be limited to a few minutes over a few grade levels."
Plus: Talking to Kids About Sex
Dr. Stephanie Whyte, the chief health officer for Chicago Public Schools, said that more than half of Chicago public high-school students reported having sex, with12 percent doing it before the age of 13, reports DNA Info Chicago. Over a third said that they had not used a condom the last time they had sex, and cases of HIV among Chicago teens have risen 43 percent since 2000. Whyte added that parents will be informed of everything that their kids are learning. Parents can also opt out of the courses in accordance with state law.
What do pediatricians say is age-appropriate for kindergarteners to know about sex? 5- to 7-years-olds are curious about how adults relate sexually, according to the healthyschildren.org, a web site of the American Academy of Pediatrics, and how that's tied to making babies. What your child learns now will stay with them as adult so it's important to teach them about sexuality in a healthy way to lay a foundation for good relationships.
Plus: Why Dad Should Be Involved in the Sex Talk Too
Do you think that sex education should be mandatory from kindergarten and up? Leave a comment.


text:
September 5, 2013
A French research team reported that follow-up studies conducted in South Africa, Kenya, and Uganda have confirmed the effectiveness of male circumcision in preventing HIV transmission. In 2006, French researcher Bertran Auvert first published research indicating that foreskin removal could reduce HIV risk among men by approximately 50 percent. A subsequent male circumcision campaign ensued in sub-Saharan Africa, where 69 percent of the world's HIV infections have occurred, according to UNAIDS.
Auvert's team returned to South Africa's Orange Farm township, site of the original research, to conduct a follow-up study of more than 3,300 male volunteers. The study collected information about sexual behavior and asked the study participants to take an HIV test. Data collected for the study indicated that multiple partners and condom use were similar among men who were circumcised and those who were not, but circumcised men were 57-61 percent less likely to have HIV. The study estimated that without male circumcision, HIV prevalence would have been 19 percent higher in the community.
Experts theorized that HIV more easily penetrated the inner foreskin of uncircumcised men because it was rich in Langerhans cells, which the virus readily entered. Auvert's research did not address whether women would benefit indirectly from lower HIV incidence among men.
UNAIDS, the World Health Organization, the Gates Foundation, and other donors have endorsed the expansion of adult male circumcision programs, which could reduce HIV transmission in areas like sub-Saharan Africa where most men were not circumcised.
The full report, "Association of the ANRS-12126 Male Circumcision Project with HIV Levels Among Men in a South African Township: Evaluation of Effectiveness Using Cross-sectional Surveys," was published online in the journal PLoS Medicine (2013; doi:10.1371/journal.pmed.1001509).
Adapted from:
France 24
No comments have been made.
The content on this page is free of advertiser influence and was produced by our editorial team. See our content and advertising policies.
|Post-AIDS 2018 Updates on HIV Cure Research
|Video SNiP: PET Scan "Hot Spots" Help Visualize Inflammatory Complication of HIV
|This Week in HIV Research: Many Black MSM on PrEP Are Already Positive
|HIV-Negative Black Gay Men: Two Recent Studies Show Some Factors That Help Them to Remain So
|What's Really Behind the Recent Decline in U.S. Hepatitis C Prevalence?


text:
Top Cars
Top 7 SUVs for City Dwellers
If you live in the city and you're searching for an SUV, our latest list is just for you. That's because we've rounded up seven of our favorite SUVs that include each of the qualities every city dweller will want: small size (for easy parking), nimbleness (for quick lane changes), ground clearance (for nasty potholes) and, of course, practicality (for holding all your gear, or your friends).
Ford Escape
The Ford Escape offers a large interior with generous rear-seat room and more cargo space than nearly all of its rivals. It also boasts a powertrain for all purposes, from the base-level 2.5-liter 4-cylinder to a fuel-saving 1.6-liter turbocharged 4-cylinder and a speedy 2.0-liter that makes a whopping 240 horsepower. Our favorite part, however, is a long list of available features, from a system that lets you swipe your foot under the bumper to open the rear hatch (useful when your arms are full) to rear cross-traffic alert, which helps drivers pull out of parking spaces in tight lots. Base pricing starts from $24,000, which is a little higher than some rivals, but base-level Escape models are also better-equipped than most.
Honda CR-V
Spend a few days with a CR-V and you'll realize the small crossover was engineered with city drivers in mind. One reason is that there's no powerful V6 designed for highway use, just a fuel-efficient 4-cylinder that boasts 23 miles per gallon in the city. There's also an impressive 71 cu ft of cargo space, which is closing in on best-in-class honors. And it all fits in a reasonably-sized wrapper that's no longer than a Honda Civic, which makes parking a breeze. The CR-V's base price of $24,500 is higher than some rivals, but many shoppers believe it's worth the premium.
Jeep Cherokee
The latest Jeep Cherokee has just made its debut for the 2014 model year, and we're already impressed. With a starting price of around $25,000 including destination, the Cherokee is more expensive than many rivals. But it's also more advanced, with a standard 9-speed automatic, an available and highly muscular V6, and optional Jeep off-road capabilities. We also love the available infotainment system, which we consider to be one of the best in the business. Fuel economy is also strong, coming in at 22 mpg in the city.
Kia Sportage
The compact Kia Sportage is an excellent crossover for city-dwelling shoppers looking for the practicality of an SUV with the driving characteristics of a car. One reason is its size: The Sportage is just 175 inches long, making it shorter and easier to park than most compact cars, such as the Ford Focus and Toyota Corolla. We also appreciate its fuel economy rating of 21 mpg in the city and its standard 182-hp engine. Best of all, we like the Sportage's base price of around $23,000 -- an excellent figure for a crossover that comes standard with an automatic transmission.
Mazda CX-5
The Mazda CX-5 is one of our favorite SUVs in general, and it's even better if you're in need of a nimble, fuel-efficient vehicle that's ready for the chores of city life. That's because the CX-5 joins the carlike handling that we've come to expect from Mazda with impressive, efficient engines that return nearly 30 mpg in city driving. We also appreciate the CX-5's long list of available safety features, including Smart City Brake Support, which helps to stop the SUV in the event of an imminent low-speed collision. Pricing is also reasonable, with a starting figure of around $23,000 including destination.
Mini Countryman
The Mini Countryman isn't the most practical small crossover, as its 42.2 cu ft of cargo space is among the lowest figures in its class. It's also not the least expensive, as a base price of $23,500 buys you a sparsely equipped base model with a weak 4-cylinder. But the Countryman does offer some of the most exciting styling in its class, and there's no arguing with the fact that it's the best-handling SUV on the road, making it perfect for avoiding potholes, bumps and other city road hazards. Gas mileage is also excellent, with base models touting 27 mpg in the city.
Find a Mini Countryman for sale
Nissan Juke
With its tiny cargo area and small back seat, the Nissan Juke may not be the most practical crossover on the market, but it's clearly the most entertaining. That becomes true the second you look at it, when you notice its unusual rear fenders, its strange headlights and its outside-the-box shape. The Juke also boasts some crazy features that you wouldn't find in a normal car, such as a G meter that shows you how aggressively you're cornering. Best of all, base pricing starts at an excellent $20,500 with shipping, and fuel economy reaches 27 mpg in the city.
What it means to you: If you live in the city, an SUV can be an excellent choice, considering all the potholes, parking curbs and other obstacles. Our latest list shows that you can combine small-car friendliness with SUV practicality.


text:
coco 1/11/14
hi- I lost my beloved 15/16 Lhasa apso this past Saturday. he had IVDD,heart mumur 5.6.,ccd-(dementia) heavy panting,blind-( a corneal ulcer.) drag his legs on the floor. incontinence etc.
I needed to get a mri/cat scan, or a fluoroscopy which would of shown us a better picture of what really was going on inside him but who has $2000 for an x-ray. I had him on a dexaasone 0.5mg pill 2x a day which is also a human pill used throughtout usa and Canada for asma.ivdd, cancer and other uses. ide effects are voiting loose bloddy stools. I only saw a little blood one night but then it stoped and his stools were solid. I do not know if he was internal bleeding. all I know he is goneever and I cannot astop crying. I 66 yrs old and there will be no ore dogs for me. I walked him in all kinds of weather rain,snow,11 1/2 yrs. I found hi bandoned in a dirt lot 6/28/2002 with a note attached to collar im homeless pls take me hoe with u. I was a animal rescuer I rescued 25 cats and 5 dogs. there was always a lot of cats in the complex . i am in bad shape myself. { edited by mod } any advise on how to deal with this sorrow. thanks lydia
Last edited by hazelrunpack; January 14th, 2014 at 07:24 PM. Reason: No personal email addresses, pls
I'm so sorry for your loss. It's never easy losing a member of our family, and one that has been a constant companion for a good number of years.
I am so sorry to hear of the lost of your beloved friend . I wish I knew what to say about dealing with lost of a beloved pet. I had to put my beloved dog down in 2008 and he was my hearing dog. I try to think of the silly things he did. It took me awhile to able to get to this place. My dog when everywhere with and people still come up to every now and than asking where my dog is. dear Coco . I stayed with my daughter and her family after I my dog dies and I laid on the floor right next to my daughter's dog and cried.
I'm so sorry to hear about Coco, sweetheart1. She had a great home with you--she was such a lucky little soul to have found you when she needed a home. And it sounds like you and she built some lovely memories. My heart aches for you.
"We are--each of us--dying; it's how we live in the meantime that makes the difference."
"It's not what you gather, but what you scatter that tells what kind of life you have lived!"
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Please accept my deep condolences Lydia.
Even though it hurts like crazy 15/16 is a nice life span for a dooger. You did your best within your means and you should be proud of the time you had together
hello to my canadian friends- thank u all for your kind words. surprisingly, im sleeping and eating. I still have his bed out and his toys and I can not seem to part with them. im not ready. many people go out within a month and get another dog, not me. I put off a knees operation for 2 years because I had no one to watch him. im 66 and alone. nobody would of tolerated his behavior. he was a wild and disobiedent dog, but I loved him with wall his flaws. I love him unconditionally.i had him groomed 2xs a year, gave him bubblt shampoos,good food, yearly dog exams. he had a coneal ulcer and I read online that is very painful for a dog. I got him optiume ointnment. I knew something was very wrong hen he did not want to go outside for his walks, he would flop down in the middle of the street when there was cars on both sides of me, I knew I had to take him to a vet. he had a mct gd2 in 2009 and had it removed. I had his teeth done twice in 2005/2009. he never let me put a toothbrush in his mouth, he put his teeth into my fingers and bite. I bought him toys. I took him to dog events, he cared less about it. I always wanted him to have a best friend dog. here in nyc there are hundreds of dog runs, even in prospect park Brooklyn there is this swimming pond just made for dogs. Lhasa are not born swimmers like other breeds-retrivers are natural born swimmers. I took him one time to the Hudson river in cronton on the Hudson,ny and it was after labor day, I took the chance I wanted to see if he would swim. he did, I let go for 5 minutes and he loved it. I was scared but I wanted him to expeience everything in life that was good. my brother yelled at me and said I shall never do that again. I said ok. now, that its over, all I have is his memory. I have empty arms, my arms at the end carried him to his bed he could not take himself to bed no more. he had ccd-dementia. I need u guys to check in on me from time to time just to see that im ok. life is very sad for me now. I have not felt happiness for a long time. I try not to cry because my eyes are swollen and it hurts. I put drops in them. bye. Lydia- forever coco rigsby mom.
Lydia you are such a wonderful caring pet owner. Many pets could only hope to have an owner like you someday.
I completely understand your feelings about how your lonely it is without our beloved pet. My first dog Winston I lost in September of 2011. It devastated me. He was my first pet and I loved him so very much. However he developed a very aggressive cancer and I lost him within 6 weeks of his diagnosis.(he was 2 months shy of his 12th birthday) It broke my heart everyday coming home and seeing his leash, bed, food bowls toys and all of the things that reminded him of me. I have no children so I felt this unbearable loneliness so I talked hubby into getting another pup. It took only a few short months and I rescued another sweet little chocolate lab pup who needed a home. I dont regret it at all and she has helped me broken heart heal.
Always remember that your boy will live on in your heart. Have you ever heard of the Rainbow Bridge? if you have a chance have a look at this website:
Have you used the PM messaging system here on pets? If so I would love to chat any time you might need to.
Have you ever considered volunteering some time to walk dogs in your area? Here is Canada the SPCA's offer a program where you can volunteer to help out by walking their dogs. They also have great needs here in rescue and in the SPCA's for people to foster dogs and cats in their homes.
Feel free to drop by the section here on pets called the TJT which is an area where we just chat about anything and everything!! If you are not sure where to find it just let me know and I can direct you.
Take care
Cindy (Sophie's Mom)
Tabitha April 10, 1995 - August 23, 2013
Bomber April 10, 1995 - July 12, 2010
Winston Nov 15, 1999 - September 15, 2011
Sophie Aug 30, 2011
He is your friend, your partner, your defender, your dog. You are his life, his love, his leader. He will be yours, faithful and true, to the last beat of his heart. You owe it to him to be worthy of such devotion.
I'm so sorry for your loss. What a wonderful life you must have had together! But it sounds like it was time for him to cross the bridge.
Lydia, I'm so sorry for your loss of Coco. Like Winston, most of us here have lost beloved pets, and for every person it is different. Some wait a year to get a new pet, others (like myself) get a new pet right away. I just can't picture life without a dog at my feet - or on my feet! It's obvious you loved your sweet Coco and gave him everything you could.
I love Winston's suggestion that you could volunteer to walk dogs for the SPCA. Can't you just imagine that Coco would be proud of you for sharing your love with those pups who need love as much as you do. If I didn't have three dogs of my own right now, that's what I would want to do.
I hope you come back here to visit us again. We're here for you if you need anything. Let me tell you from my own experience, that Winston's offer of moral support is sincere. She's a lovely person with so much love and support to offer people.
Hi Lydia,
Very sorry for your loss. All of us who have lost a beloved pet feel your same pain. The suggestion of walking dogs for the SPCA helped me when I lost my dog Sparky many years ago. I then went on to fostering for a local rescue which may help you. The time spent helping other animals will benefit you both and you never know, you may just fall in love with a foster and make it your own
I'm very sorry for your loss.
|Thread Tools
|Display Modes
Linear Mode


text: I'm currently quoting a boiler for a community development block grant and the spec calls for a boiler with a tankless coil and a 30 gal. super-stor on the side. Is there a real cost savings or advantage to the home owner by doing this or are they better off going with just the tankless coil or just the super-stor and save money on the installation cost?


text:
Sign Up
New Arrivals
Baby Transport & Safety
4D Flash Cards
Room decor
Newborn Apparels
Kids Bicycle, Trikes
Wedding Attires
Food Supplements
Baby Rompers
Bibs and Jablas
Toys and Games
Boys Daily Casuals
Girls Daily Casuals
Girls Western Wear
Boys Western Wear
Girls Ethnic Wear
Boys Ethnic Wear
Frocks and Dresses
Maternity Care
Skin and Bathing Care
Baby Potty Training
Art & Crafts
School Supplies
Pacifiers and Teethers
Baby Essentials
Shop by Brand
1 to 2 Years
2 to 4 Years
4 to 6 Years
6 to 8 Years
8 to 10 Years
10 to 12 Years
New User? Click to Register
Login as Existing Customer
We @ Nicabo.com spring a shop sensational online store for your kids and toddlers. In your paternal and maternal bliss, Nicabo empathize a strong affiliation between you and your fellow kids, new born babies, children and newmoms. The quite interesting and passionate deal of a mother is to bestow the needs of her new borns, toddlers, infants, her boy / girl. Correspondingly, the lovable father would be very enthusiastic and excited to transact the love of her boy baby / girl baby through their new-moms. In fact, delivering the care and affection on infants, kids and their new-moms are inevitable. This aspiration beyond a boundary fulfils at Nicabo.com, where we extend our hands as the best Kids Online Shopping Store emphasis on both baby care products and mother care products through the renowned retail sellers in India.
We are one of the largest Kids Online Store in India, value your interest, preference and care of your beloved ones. Nicabo engage in delivering a wide range / mass of branded, top-notched goods in the all segments of Baby care products, Kids products, Mom care products & Maternity comforts for our happy customers in India. Exploring Nicabo.com, promises your interest safeguard and astonishing smile of your beloved ones.
At Nicabo, we ease your best-pick by online shopping of baby clothing, kids wear, infant & newborn clothing, footwear, baby gear, baby & kids toys, indoor & outdoor games, kids furniture, kids room decors, diapers, feeding & nursing, baby nutrients, kids nutrients, skin, health care, bath care, beddings, grooming, room furnishing, nursery products, gifts, school wears, kids learning and education, bags & trolleys, kids fashion accessories, books, CDs, rain accessories, party supplies and lot more amenities of kids and babies from leading national and international brands at bigger offers and discounts.
Maternal and paternal care products down the line as maternity wears, maternity accessories, personal care, nursing etc., are offered at one-click shopping in Nicabo online store.
Trend products on a brand hub @ nicabo includes Adore, Avengers, Barbie, Bebe comfort, Disney, Easy Fit, Ecobaby, Funskool, Hasbro, Himalaya, House of Napius, Jaybee, Johnson's, Kingstar, Kittens, Kingstar, Little Darlings, Little Moppet foods, Littleopia, Love Baby, Mamy Poko, Mee Mee, Nestle, Nuby, OK Play, Ole Baby, Oral -B, Pampers, Playskool, Popsicle, Quick Dry, Shree Shubh, Summer Infant, Tiny Baby, Thomas & Friends, Tommy Hilfiger, Tots and Moms, Trendy Girls, Tupperware, Urb-N-Angels, WWE, Warner Bros, Winther, Wonderland, Wow!, Yellow Bee, You Got Plan B, Zeme, Zephyr & many more line of brands.
Favoring to the customer convenience and handiness, can shop on Nicabo.com - Mobile app fit on Android.
Best offers and deals for newborn, toddler and kids products assured in this one roof. Your savings are concerned by us via implausible Nicabo offers & deals on the wide range of quality products. Customer satisfaction to the maximum extent is the motto of Nicabo.com on deal throughs including best offers, greater discounts, seasonal deals, cashbacks, first time user offers, WC15 coupon offers, flats, cyclic flats & many more benefits.
© 2017 Kidzvoo Private Limited. All Rights Reserved.


text:
VANCOUVER, BC - In their second home match of the 2012 Major League Soccer season, Vancouver Whitecaps FC (2W-0L-1D) were held to a goalless draw by Eastern Conference club D.C. United (0W-2L-1D) on Saturday evening.
In a game that saw few chances at both ends, Whitecaps FC could not unlock their visitors from the American capital, as United worked hard to earn their first point of the season following two straight defeats to start their 2012 campaign. While the Blue and White will be frustrated not to have claimed a third-straight MLS win in front of a passionate crowd of 19,394 on Bell Pitch at BC Place, they set new club records by registering a third-straight clean sheet as an MLS club and extending their undefeated streak in the league to three games. For a third-straight match, resolute defending and more fine goalkeeping from Joe Cannon meant Vancouver have still to concede a goal in regular season play this year.
"A little bit disappointed that we couldn't take advantage of a few opportunities that we had," said Whitecaps FC head coach Martin Rennie. "But I thought it was quite an exciting game. I thought that D.C. United certainly played well and made it difficult for us. I know they'd had a couple difficult results, they certainly were up for the game, and worked hard for their point."
After claiming their first away win in MLS last weekend, Rennie named an unchanged side from the starting XI that earned the 1-0 victory at Chivas USA. United head coach Ben OIsen, meanwhile, played a potent attack in his 4-3-3 formation. Designated Player Hamdi Salihi, former Toronto FC striker Maicon Santos, and captain Dwayne De Rosario all started up front for the visitors.
A beautiful spring evening saw Whitecaps FC open the BC Place roof for the first time this season, though the open air had little impact on the level of vocal support that 'Caps fans gave their home side during the weekend contest. The first half was a scrappy and competitive affair, illustrated by the bookings to Whitecaps FC striker Eric Hassli and United's Brazilian forward Santos before the break.
Vancouver had two half-chances in the first 45 minutes. Argentine centre back Martin Bonjour, who put in an excellent defensive display, headed Camilo Sanvezzo's free kick over the United crossbar just five minutes in before Hassli struck the D.C. side-netting with a low header from Camilo's pin-point cross on the half-hour mark.
United closest effort to a first-half goal came from Albanian international Salihi, but his header from a Nick DeLeon corner flew over the 'Caps crossbar on 32 minutes. It resulted in a goalless scoreline at halftime.
While the effort was there from both sides, a decisive goal remained elusive in the second half. Whitecaps FC midfielder Matt Watson had two efforts after the restart, with the Englishman's best strike coming on 59 minutes, as he volleyed a powerful shot wide of the United goal.
Credit must go to D.C. for their attempt to claim their first win of the season. The visitors had the best chance of the match on 67 minutes, as United's two Designated Players combined from a D.C. corner. Substitute Branko Boskovic's set-piece found Salihi in the six-yard box. His close-range header was brilliantly saved by Cannon on the goalline before the danger was cleared by Davide Chiumiento and Bonjour. The Vancouver number one will surely be in line for another MLS Save of the Week honour after that reflex stop. United captain De Rosario then threatened with three opportunities, but Cannon and his lack of accuracy to hit the target meant the Canadian international would not be on the scoresheet at BC Place.
Both sides kept battling away to the end, with a further five minutes of time added on played by match referee Kevin Stott. His final whistle, however, confirmed a share of the spoils in this lone regular season meeting between Vancouver and D.C.
Whitecaps FC will now head out on the road for two games, starting next Saturday when they visit Chester, Pennsylvania, for their lone regular season clash with winless Eastern Conference club Philadelphia Union. United, meanwhile, return home to Washington, D.C., for two matches, starting with their lone regular season meeting versus Western Conference side FC Dallas next Friday night.
Budweiser Man of the Match: Jay DeMerit
Scoring Summary:
Match Stats:
Shots: Vancouver 8 - D.C. United 12
Shots on Goal: Vancouver 0 – D.C. United 3
Saves: Vancouver 3 – D.C. United 0
Fouls: Vancouver 11 – D.C. United 15
Offsides: Vancouver 4 – D.C. United 3
Corners: Vancouver 3 – D.C. United 5
33' - VAN - Eric Hassli
35' - DC - Maicon Santos
70' - DC - Chris Pontius
Vancouver Whitecaps FC
1.Joe Cannon; 12.Young-Pyo Lee, 15.Martin Bonjour, 6.Jay DeMerit, 4.Alain Rochat (3.Jordan Harvey 57'); 20.Davide Chiumiento (23.Long Tan 86'), 16.Matt Watson, 27.Jun Marques Davidson, 37.Camilo Sanvezzo; 7.Sebastien Le Toux, 29.Eric Hassli
Substitutes not used: 18.Brad Knighton, 17.Omar Salgado, 19.Carlyle Mitchell, 26.Floyd Franks, 28.Gershon Koffie
D.C. United
31.Joe Willis; 3.Robbie Russell, 4.Brandon McDonald, 19.Emiliano Dudar, 21.Daniel Woolard; 2.Danny Cruz, 11.Marcelo Saragosa, 18.Nick DeLeon (13.Chris Pontius 57'); 7.Dwayne De Rosario, 9.Hamdi Salihi (16.Josh Wolff 80'), 29. Maicon Santos (8.Branko Boskovic 80')
Substitutes not used: 50.Andrew Dykstra, 5.Dejan Jakovic, 20.Stephen King, 22.Chris Korb


text:
Unlike many other famous moms-to-be, Real Housewives of Atlanta star Phaedra Parks doesn't consider her pregnancy as an excuse to overindulge.
"Some people subscribe to the myth, 'I'm eating for two people,' " Parks tells PEOPLE.
"Well, not really. The other person is half of a pound. I wouldn't really count that as an individual. It's obviously a living organism, but something weighing 7 lbs. doesn't really allow you to eat two meals. Doctors say you only need an additional 500 calories."
Parks – who already has a son Ayden, 2, with her husband Apollo Nida – doesn't find it difficult to remain a healthy weight while pregnant.
"I don't count calories," she says. "I just try to eat organic, healthy food. I eat a lot of small meals per day. If I want something, I try to eat it in moderation if it's something that's not good for me. I don't really have any cravings. The only thing I [craved] during my last pregnancy were oranges. I love citrus fruit."
Adds Parks, "I really have little or no time to ponder about food all day. I just eat to live. I don't live to eat. Some people are living to eat, and I try to have a healthy relationship with food."
Nutrition habits aside, Parks – who recently released a new exercise video, Phine Body: Volume 2, on Jan. 31 – stays in shape with a rigorous fitness routine.
"Now I'm really doing a lot of water aerobics and stretching," she explains. "When you're pregnant, everything's moving and shifting and you've got aches and pains that you never even knew of."
The new video, she says, "focuses on arms, chest area, the entire body. It's a little more challenging than the first one, but it's still anaerobic. You're going against your own body weight and you're only using household products – milk jugs, cans of green beans, things that everyone has in the house. We try to make it easy for everyone."
Once baby is born, Parks strongly advises breastfeeding for getting a woman's body back post-pregnancy.
"I tell people to nurse their baby," she says. "It tightens up your uterus. It brings everything back in places very quickly. And it cuts down on buying milk and going to the grocery store. Milk does a body good, and if you can make it yourself, then why not?"


text:
Emma the tiger shark and a bunch of reef sharks and lemon sharks feed on a bit of fish bait (bones, mostly). Bahamas.
3D anaglyph (red/cyan) glasses are required for this video.
A couple more:
3D shark video from the Bahamas
Started by echeng, Sep 19 2010 07:46 AM
1 reply to this topic
Posted 19 September 2010 - 07:46 AM
Posted 19 September 2010 - 11:25 AM
Very very cool. The 3D's working really well for me. Would love to see it projected.
EOS 7D, Nauticam housing, EOS 5D II, Ikelite, Inon z240, Inon D180, Tok 10-17, 15 FE, 17-40, 105 Macro
Sony HC7, Gates Housing
Visit My Website
Sony HC7, Gates Housing
Visit My Website


text:
Am I Seeing Double 2
- $1.99
- Published By: eXtasy Books
- Author: Roland Singleton
- Page: 40
- Word Count: 8561
- Publication Date: January 26, 2013
- Series: Am I seeing Double #2
- Heat Level:
- Available Formats: Adobe Acrobat, Epub, Hiebook, Microsoft Reader, Mobipocket, Mobipocket (.mobi), Palm DOC/iSolo, Rocket, Sony PDF
- Categories: Contemporary,
Qty + -
How do you handle trouble if you can't control it, particularly if it's double trouble.
Writing books and living with twins is getting hectic so he goes to the countryside for a break or is it supposed to be.
To read excerpts, you need to have an account with us. Please log in first.


text:
Using six 2.6TB Fusion ioMemory™ ioDrive®2 Duo drives, the Universities of Michigan and Victoria are sharing massive volumes of data with the CERN Laboratory and 100 other computing centers. The solution may expedite the potential discovery of new particles and forces that will help explain the nature of the universe.
Through the use of Fusion ioMemory™ PCIe solutions, the University of Michigan and University of Victoria are implementing a multi-site supercomputing project to help them share massive volumes of data among the CERN Laboratory in Geneva, Switzerland and 100 computing centers around the world. The solution has the potential to accelerate access to physics data—allowing teams of physicists to expedite the potential discovery of new particles and forces that will help explain the nature of the Universe.
Randall Sobie,
Institute of Particle Physics Research Scientist and Professor at University of Victoria
Francois Englert and Peter W. Higgs received the Nobel Prize in physics for the theoretical discovery of a mechanism that contributes to our understanding of the origin of mass of subatomic particles. This mechanism was confirmed through the discovery of the predicted fundamental particle by the ATLAS and CMS experiments at CERN's Large Hadron Collider (LHC).
The Large Hadron Collider (LHC) is the world's largest and most powerful particle accelerator. Initiated on September 10, 2008, the LHC consists of a 27-kilometre ring of superconducting magnets that contain a number of accelerating structures to boost the energy of the particles. Inside the accelerator, two high-energy particle beams travel at close to the speed of light before they are made to collide. They are guided around the accelerator ring by a strong magnetic field maintained by thousands of superconducting electromagnets, which are built from coils of special electric cable that operates in a superconducting state, efficiently conducting electricity without resistance or loss of energy.
All of the controls for the accelerator, including its services and technical infrastructure, are housed under one roof at the CERN Control Centre in Geneva, Switzerland. From here, the beams inside the LHC are made to collide at four locations around the accelerator ring, corresponding to the positions of four particle detectors—ATLAS, CMS, ALICE and LHCb. The LHC is a machine built to study the "Big Bang" when the Universe was formed.
ATLAS is one of the particle physics experiments at the LHC that is dealing with both trying to discover the fundamental laws of physics and with searching for new discoveries in the head-on collisions of protons of extraordinarily high energy. At approximately half the size of Paris' Notre Dame Cathedral, ATLAS is about 45 meters long, more than 25 meters high, and weighs about 7,000 tons—the equivalent of one hundred 747 jets.
ATLAS is learning about the basic forces that have both shaped our Universe since the beginning of time and that will determine its fate. As the particles crash together in the center of ATLAS, they produce tiny fireballs of primordial energy, thereby recreating the conditions that existed at the birth of the Universe. Among the possible unknowns that ATLAS is exploring are extra dimensions of space, unification of fundamental forces, and evidence for dark matter candidates in the Universe. Due to the discovery of the last missing pieces of the Higgs boson, further data will allow in-depth investigation of the boson's properties, and thereby, of the origin of mass.
The Challenge
The research at the LHC involves a very large and distributed collaboration among hundreds of organizations and thousands of physicists. The result is a huge amount of data; ten petabytes of data is transmitted each year.
The current challenge is to deploy an infrastructure that can support the data being scanned for new discoveries. The key to enabling these scientific discoveries is getting data from the source to the remote local sites as rapidly as possible. The ATLAS data sample is approximately 170 petabytes and must be transferred from CERN to other centers around the world at 100 gigabits per second (Gbps) to enable scientists to rapidly access and analyze data, and speed up discoveries.
In Spring 2015, the LHC will start colliding elements at the highest energies ever achieved in a particle accelerator. With this in mind, the physicists at the Universities of Michigan and Victoria needed to create a data transfer architecture based upon a single server that is able to transfer data among 100 computing centers around the world at 100 Gbps speeds.
Research sites typically make local copies of data when an interesting data set or anomaly has been identified. As sites begin to upgrade to 100 Gbps network connections, the challenge is to utilize the bandwidth efficiently and deploy a subsystem that can deliver at that level. To date, there has not been a vendor with a 100GB interface card.
Physicists from University of Michigan and University of Victoria are working together to develop a simple grid framework infrastructure that can utilize wide area network 100GB connections to enable data to be scanned by local sites for new physics. Large local sites must have the ability to move data across many servers and therefore need the network cache to source and sync data from many sites to distribute locally, as smaller sites deploy a single server to utilize the data.
"The ATLAS and CMS supercomputing projects are very large international projects, each involving approximately 3,000 researchers and most of the world's countries. These are long term projects—they started 20 years ago and will continue for another 20+ years," said Randall Sobie, Institute of Particle Physics Research Scientist and Professor at University of Victoria.
The Solution
The Caltech, University of Michigan, and University of Victoria teams at Supercomputing 2014 (SC14) had been aware of SanDisk's Fusion ioDrive® solutions for some time. NAND-based and PCIe-based storage solutions were intriguing due to the promise of obtaining better performance than RAID storage systems. The team expected that using the SanDisk drives was the only way to get sufficient performance from a single box.
Working with Fusion ioMemory solutions, the University of Michigan and University of Victoria research teams deployed a single server storage environment to fuel their multi-site supercomputing project. It was necessary that the solution deliver massive data transmissions, while eliminating the need for a multi-server configuration and reducing complexity, cost, and points of failure. The chosen flash memory solution also dramatically reduced the server footprint needed to transmit these enormous datasets. By utilizing Fusion ioMemory PCIe solutions, the universities have accelerated access to data, allowing physicists to expedite the potential discovery of new particles and forces that will help explain the nature of the Universe.
The design tested at SC14 was focused around building a single server with the capability of meeting data transfer needs of a site connected at 100GE. One high performance server resided in the University of Michigan booth at SC2014 and a second high performance server resided at the University of Victoria. High performance networks were provided by CANARIE, BCNET, CenturyLink, and SCinet in collaboration with the Caltech Networking Team.
At the University of Victoria, a dedicated 100G circuit was established using a Brocade MLXe-4 and CFP2 module to connect to the SC14 show floor. High-performance data transfer nodes were architected using a Dell R920 server equipped with six 2.6TB Fusion ioMemory ioDrive2 Duo solid state storage (SSD) drives that were connected to the MLXe-4 with a 100G CFP2 module and three 40GE NICs. An OpenDaylight controller employing custom multipath extensions was implemented on the SC14 show floor to control the MLXe-4 at the University of Victoria.
Regarding the support from SanDisk, Ian Gable, physics computing specialist with University of Victoria, said, "We were extremely impressed with the deep technical expertise of the SanDisk solutions architect. The late nights and hard work provided by SanDisk were contributing factors to our success."
The Result
The researchers were very happy with the initial results and declared the performance of the SanDisk Fusion ioDrive2 Duo cards as nothing short of astonishing. The solution achieved 137 Gbps read-to-disk locally and 113 Gbps write-to-disk locally.
Each Dell server drove the network memory at a flat 99.7 Gbps from the University of Victoria via the Brocade MLXe-4 to the Caltech booth and then to the University of Michigan booth on the SC14 show floor—illustrating a loss-free network path between the two sites. Reading from disk using SanDisk Fusion ioDrive2 Duo drives resulted in 65 millisecond latency between the two sites at 73 Gbps. Writing occurred at 60 Gbps. These results indicate that a single server can handle the needs of a 100G wide area circuit.
"We believe that there is potential to improve on these results with further testing and tuning," commented Shawn McKee, physics researcher at University of Michigan. "However we are quite satisfied with the progress made during the limited time frame of SC14. Using a single 40GE network card we were able to copy data from disk to disk at 37.5 Gbps with just two SanDisk Fusion ioDrive2 Duo cards. This indicates that we should be able to reach our final goal of 100G read and write using this extremely capable hardware."
To take advantage of these results in production, it will be necessary to fully explore the interaction among all of the components of the long latency, high-bandwidth path and with the multiple levels of caching and buffering along the end-to-end system—Application, Drive, Filesystem, and Network.
"My colleagues and I are proud and excited that we have now found a way to accelerate the discoveries made for each of these projects with the help of flash memory solutions from SanDisk," said Sobie.
Each University now has a production 100G WAN network connection and will continue to boost the efficiency of the WAN transfer. They will then deploy this formula at other scientific sites.
"SanDisk is thrilled to be working with the teams at the University of Michigan and University of Victoria to help fuel their success by providing fast, cost-effective, and highly scalable flash solutions to increase data access," said Sumit Sadana, executive vice president and chief strategy officer, SanDisk. "By utilizing flash technology, the researchers can cost-effectively transfer massive amounts of data over long distances, ultimately enabling them to reach new discoveries faster."
The Future
The ATLAS accelerators have been in shutdown since 2013 to undergo upgrades and infrastructure changes. Previously configured for 8 to 13 teraelectronvolts (TeV), ATLAS will be newly configured to run at 14 TeV to accommodate physics data that will be generated beginning in May 2015. Teams are in the process of upgrading equipment, software, and frameworks to implement a proof of concept infrastructure that demonstrates what options are capable of enabling their data needs. Individual sites will then determine what infrastructure will be adopted depending on yearly budgets and available equipment.


text:
RBA's news for banks and currency traders
RBA governor Glenn Stevens and Financial Services Minister Bill Shorten have both thrown "knuckle-balls" into the evolving policy debates on how to prevent banks and non-banks from collapsing.
Stevens also revealed he's taken a directional punt on the Aussie dollar.
In a conversation with Shorten during the week I argued that the way to prevent catastrophes like Banksia from reoccurring is to insist that all non-banks are supervised by the Australian Prudential Regulation Authority.
This draws on a policy idea I've outlined here before: if you want to get into the business of supplying credit in a serious way, you should be subject to some minimum level of prudential oversight.
I told Shorten that Banksia disclosed 18 per cent default rates in its June 2011 accounts – as high as US sub-prime levels – that would never have happened on APRA's watch.
I also suggested that notwithstanding Australian Securities and Investments Commission chairman Greg Medcraft's fine efforts to staunch the Banksia problems, prudential analysis was not ASIC's domain.
Of course, APRA would not like the proposal, because it means more work for it. This is why Shorten's comments about extra resourcing are on the money. Since there are so few non-banks left in Australia, it is hard to imagine that it will be any great burden.
The RBA's governor also had some big news for Australia's $300 billion major banks. These remarks were not in the prepared text of his speech on Wednesday, but in the 30 minutes of off-the-cuff answers to questions that followed it.
Astonishingly, they were completely missed by Australia's media, with the exception of reporters from The Australian Financial Review.
In the past seven days, debate has raged about whether Australia's biggest banks should be forced to comply with the International Monetary Fund's recommendation that they hold more first-loss, tier one capital as "too-big-to-fail" intermediators.
This is, in fact, just the standard prescription for banks that are "systematically important" to local economies under the new global rules called Basel III.
In a report last Friday, the IMF observed that Australia has one of the most concentrated banking systems in the world and that the majors "enjoy a funding cost advantage" deriving from "implicit government support". That is, they can source money more cheaply than their competitors because rating agencies and markets believe they are more likely to be bailed out by government.
The IMF concluded, as I have, that the majors "should bear some of the cost of mitigating systemic risk" via additional tier one capital.
In a column on Monday I said bank bosses and shareholders would resist this idea, while creditors, such as bond holders and depositors, should welcome it. An increase in equity capital by definition reduces leverage and the risk of default, but it also hair-cuts returns to equity investors.
Sure enough, the AFR reported that two major bank chairmen had "ruled out" capital increases (this is actually APRA's decision), and that former Commonwealth Bank chief executive David Murray thought it was a bad idea.
Yet Stevens more or less ended the debate on Wednesday night.
When asked about the impact of the new banking rules, Stevens said that the majors would be captured as "domestically systematically important financial institutions" and, crucially, will have to "hold a little bit more capital, not on the same magnitude as the JPMorgans … but a little bit more".
The Basel Committee has recommended harsher capital levies for banks that have businesses that span global markets. The majors have been exempted from this extra charge for as long as they have a single market focus. This makes ANZ's Asian foray interesting, as the RBA has noted in its financial stability work.
Stevens was unfazed by the challenge, arguing, "these things I don't think are going to be a great drama for us … the capital shortfall that would exist under the new rules is much smaller generally for our banks than it would be for many others".
Just as fascinating was Stevens' defence of the measures. He said that prior to the credit crisis the cost of banking had been too cheap, and taxpayers had been required to provide emergency support that additional capital would mitigate:
"Insisting on more capital to lessen the probability of the state having to step in again – it raises the cost of intermediation to the community, that's correct – but I think the community just has to accept that the price of intermediation appears to have been too low before."
The RBA governor also weighed into the Aussie dollar debate. The central bank is in pro-active "jaw-boning" mode, and Stevens was happy to say the currency "is a bit on the high side given what's happened [and] I'm a bit surprised it hasn't come down".
This sat awkwardly alongside attempts to negate news that the IMF is considering classifying the Aussie dollar as an official reserve currency. According to Stevens, the Aussie had been a reserve currency for 25 years. But he conceded that its behaviour in recent times did not accord with historical patterns (hence the "surprise" at its vaulted level).
As I explained in this column, sovereign and central bank diversification into Aussie dollars over the past two years has been the single most important dynamic influencing our exchange rate.
Stevens disclosed that the RBA has started backing its belief that the currency may be overvalued: "As for the so-called "passive intervention", let's say that was customer business that we decided to keep on the balance sheet because the prices seemed attractive to do that as this time."
Taxpayers will hope he gets his bets right.
The Australian Financial Review


text:
September 18, 2012
The newly approved four-in-one HIV drug Stribild (elvitegravir/cobicistat/FTC/tenofovir), also known as the "Quad," has gotten a tentative nod from the panel of experts that revises the official U.S. HIV treatment guidelines for adults and adolescents. The panel recommended the drug as an "alternative" first-line antiretroviral treatment regimen, placing it below the four existing "preferred" regimens.
The decision to initially list Stribild as an alternative medication is mostly based on our relative lack of information about the drug's long-term effects. The panel cited study data that only extend 48 weeks from the time people began taking Stribild, potential concerns regarding creatinine clearance and kidney damage, and a lack of data on women and on people with advanced HIV disease. The panel also noted that the drug carries a large number of drug-to-drug interaction risks and must be taken with food, which can make adherence more difficult.
The full announcement from the U.S. Department of Health and Human Services HIV treatment guidelines panel is below.
Elvitegravir (EVG) is a new HIV-1 integrase strand transfer inhibitor (INSTI). It was recently approved by the U.S. Food and Drug Administration as a part of a co-formulated product in combination with cobicistat (COBI), tenofovir (TDF), and emtricitabine (FTC), as a single-tablet (EVG/COBI/TDF/FTC), once-daily regimen for antiretroviral treatment (ART)-naive HIV-infected patients with estimated creatinine clearance (CrCl) of >70 mL/min.1
The Panel recommends:
See Tables 5a and 5b in the current guidelines for a list of the Panel's preferred and alternative regimens for treatment-naive patients.
In two Phase 3 randomized clinical studies of 1,408 treatment-naive patients (89% male), co-formulated EVG/COBI/TDF/FTC was non-inferior to co-formulated efavirenz/tenofovir/emtricitabine (EFV/TDF/FTC)2 and ritonavir-boosted atazanavir plus tenofovir/emtricitabine (ATV/r + TDF/FTC),3 with similar proportion of participants achieving HIV RNA <50 copies/mL at Week 48. Rates of virologic failure were low and comparable across study arms. INSTI-associated mutations were identified in 11 of 26 subjects in the EVG/COBI/TDF/FTC arms who failed therapy and had genotype data available.2,3 These mutations conferred varying degrees of cross-resistance to raltegravir and high rates of co-existing nucleoside analog resistance.1 The most common clinical adverse events reported with EVG/COBI/TDF/FTC were diarrhea, nausea, and headache.
EVG is metabolized through CYP3A enzymes. CYP3A inhibitors or inducers can significantly affect its metabolism. COBI is a potent CYP3A inhibitor with no activity against HIV. It serves as a pharmacokinetic enhancer of EVG, with resultant increase in EVG's systemic exposure and prolongation of its elimination half-life, which allows for once-daily dosing.4 As a potent CYP3A inhibitor, COBI can inhibit the metabolism of other CYP3A substrates, including other antiretroviral (ARV) drugs such as HIV protease inhibitors, non-nucleoside reverse transcriptase inhibitors, and maraviroc. Currently, co-administration of EVG/COBI/TDF/FTC with other ARV drugs is not recommended. It should be used with caution with many other CYP3A substrates as noted in the product label.1
COBI inhibits active tubular secretion of creatinine, resulting in increases in serum creatinine and a reduction in estimated CrCl without reducing glomerular function.5 In the Phase 3 trials, more subjects discontinued study drugs because of renal adverse events in the EVG/COBI/TDF/FTC arms (eight subjects) than in the comparator arms (one subject in the ATV/r + TDF/FTC arm; none in the EFV/TDF/FTC arm). Four of the eight subjects in the EVG/COBI/TDF/FTC arms who discontinued study drug had evidence of proximal tubular dysfunction. Patients on EVG/COBI/TDF/FTC should be switched to an alternative ART regimen if estimated CrCl decreases to less than 50 mL/min. Concomitant use of nephrotoxic drugs should be avoided.
EVG/COBI/TDF/FTC is an effective INSTI-based regimen in HIV-infected, ART-naive patients. The coformulation and long half-life allows for one tablet, once-daily dosing. Limitations include a significant potential for drug-drug interactions, the availability of only 48 weeks of safety data, usage limited to individuals with pre-treatment CrCl >70 mL/min, a possible increased risk of proximal renal tubulopathy, limited data in patients with advanced HIV disease and in women, and the need for the drug to be taken with food. Based on these factors, the Panel recommends EVG/COBI/FTC/TDF as an alternative regimen for ART-naive patients (BI).
aRating of Recommendations: A = Strong; B = Moderate; C = Optional
Rating of Evidence: I = data from randomized controlled trials; II = data from well-designed nonrandomized trials or observational cohort studies with long-term clinical outcomes; III = expert opinion
No comments have been made.
The content on this page is free of advertiser influence and was produced by our editorial team. See our content and advertising policies.


text:
Busta Rhymes, Debbie Harry, Puff Daddy, Jay Z and several others stole the show last weekend during the Coachella Valley Music & Arts Festival in Indio, surprising fans who braved the wind and setting social media in a frenzy all over the world. While those performances can't be replicated, the final weekend of the festival is expected to host another wave of stunning performances starting today.
The desert's mega music festival kicks off its last run of the year with headliners OutKast, Muse and Arcade Fire, but if there's anything first weekend festivalgoers learned, it's to pay attention to the smaller type on the festival's lineup. Acts such as Chance the Rapper, who brought out Justin Bieber; Solange who brought out sister Beyoncé; and Jhené Aiko, who brought out Childish Gambino and Drake, all did their part in making the festival special for their fans and there's no telling what's in store this weekend.
For all the Coachella buzz and live updates from the festival field, be sure to go to www.dailybulletin.com/coachella.


text:
Shop our Holiday Gift Guide! Discover now
Sign up for text alerts & get 3x points on your order!
Everyone else: Complimentary shipping on $49 or more
You have no items in your shopping cart.
Availability: Out of stock
PLUS, receive updates on SPECIAL EVENTS and OFFERS at your nearest Cos Bar!
Complimentary shipping for B. Cos members, no minimum required. Not a B. Cos member? JOIN NOW


text:
The Space Shuttle Atlantis lifted off at 11:20 a.m. Eastern time July 8, marking the beginning of the end for the shuttle program.
But although Atlantis' 12-day mission will bring the shuttle era to a close, a lot of the technology developed for the program will live on in terrestrial surroundings.
From its inception in 1958, NASA has developed or contracted for technology that eventually turned up in people's homes and cars, from better water filters and freeze-dried food to wireless devices and Dustbusters. (But not Tang, as an entire generation of Americans grew up believing. It turns out that Tang was around before astronauts started drinking it in space. The inventions of Teflon and Velcro are apparently other common myths about the space program.)
In fact, NASA puts out an annual publication, Spinoff, devoted to its commercialized technology, which has continued through the shuttle program's 30 years.
So as Atlantis orbits the globe on the final shuttle flight, we pay tribute to just a few of the technologies that have grown out of the program.
Artificial heart. NASA didn't invent the artificial heart, of course, but the technology used in space shuttle fuel pumps led to the development of a miniaturized ventricular assist pump by NASA and renowned heart surgeon Dr. Michael DeBakey. The pump is 2 inches long by 1 inch in diameter and weighs less than 4 ounces. It is undergoing European clinical trials where it has been successfully implanted into more than 20 people.
Running cool. Materials from the shuttle's thermal protection system are used on NASCAR racing cars to protect drivers from the extreme heat generated by the engines.
Cancer treatment. Experiments with growing plants in space led to the development of a lighting technology, using light-emitting diodes, that is now being tested as a way to treat brain tumors in children. The method, called photodynamic therapy, is being studied at the Medical College of Wisconsin in Milwaukee.
Balance evaluation systems. Astronauts returning from space tend to be a bit wobbly at first, so NASA built devices to measure their equilibrium that are now used to diagnose and treat patients suffering head injury, stroke, chronic dizziness or central nervous system disorders.
Liquid metal. It might not be the shape-shifting stuff in "Terminator 2," but efforts to develop strong, light, synthetic material for shuttle flights led to the development of "liquid metal," an alloy more than twice as strong as titanium. It's used in metal baseball bats, jewelry, military armor and medical instruments.
Safer jewelers. The heat shields used on the shuttle give jewelers a safer soldering base than the old-style blocks that contained asbestos fibers.
Land mine removal. The high-octane fuel left over from shuttle flights is used disable land mines. The fuel is put into a flare device, placed next to a mine and ignited via a remote-controlled match. The fuel burns away the mine's explosives, rendering it harmless.
Better prosthetics. The light, strong, foam insulation used on the shuttle's external tank has replaced the plaster used in master molds for prosthetics.
Video stabilization software. The image processing NASA uses to evaluate and analyze shuttle launch videos and meteorological images is used by law enforcement to enhance grainy videos in search of clues or information such as a license plate number. It also can be used for medical imaging or other scientific applications.
About the Author
Kevin McCaney is a former editor of Defense Systems and GCN.
E-Mail this page
Printable Format
Challenger - Jan 1986 and Columbia - Feb 2003
I believe the author is making a reference to mana falling from heaven, not a shuttle falling from the sky. Mana being the essence of magic/creation, inspiration, etc. (you can look it up for more) Columbia fell about 20 yrs ago, you need to move on with your life. Interesting article, by the way.
Actually, James from Wisconsin, you're being too sensitive. It's a takeoff on the 1976 movie title, and incidently, "falling" is popularly used to describe the shuttle leaving its earth orbit for return to earth. Thank God for gravity.
Your name for this article is gratuitous and unnecessary. Fell to Earth and Space Shuttle should not be in the same sentence, especially since Columbia. Unnecessary flaw in an otherwise well-intentioned and informative article.
Actually it lifed off at 11:28 EDT but..
Advanced Search
8251 Greensboro Drive, Suite 510
McLean, VA 22102
© 2018 1105 Media, Inc.
8251 Greensboro Drive, Suite 510
McLean, VA 22102703-876-5100 © 1996-2017 1105 Media, Inc. All Rights Reserved.


text:
Casio XJ-A255 LED projector (demo unit) The Casio Signature Model Projectors have increased I/O connectivity, are DLP 3D Ready and have auto brightness adjustment to save power and reduce eye fatigue.
The USB models allow Wi-Fi connectivity so users can display wireless presentations from a laptop or by using MobiShow, a smart phone application, where presentations can be made using a mobile device.
3 years parts and labor warranty